
The Human Upgrade: Biohacking for Longevity & Performance
1,548 episodes — Page 13 of 31

Ep 910Happiness Starts with Your Brain Type – Dr. Daniel Amen : 910
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Hydrate with Electrolytes: https://DrinkLMNT.com/DAVE, get a free LMNT Sample Pack with 8 single-serving packets for the cost of shipping ($5 for U.S. customers) Strengthen Your Back, Align Your Spine: https://bodyaline.com, use code DAVE100 to save $100Fix Your Feet: https://www.vivobarefoot.com/us/daveasprey, use code ASPREY20 to get 20% off your first order and access to the VHealth Barefoot Movement online coursesIN THIS EPISODE OF THE HUMAN UPGRADE™...“Americans are the unhappiest they have been since the Great Depression,” says Dr. Daniel Amen. But he’s determined to change that. He’s a physician and double board-certified psychiatrist who looks at happiness as a brain function. After studying more than 200,000 brain scans of people from 155 countries, Dr. Daniel Amen discovered five primary brain types and seven neuroscience secrets that influence happiness.“I wanted to spend my time and energy and research on happiness because, ultimately... happiness is a moral obligation because of how you impact other people,” Dr. Amen says. “The big central point [is] the brain is the organ of happiness, and if your brain is not healthy, you are not likely to be happy.”What makes you happy? The answer lies in knowing your specific brain type and how it’s being influenced by seven specific chemicals.Happiness originates in distinct brain regions: pleasure in the orbitofrontal cortex; motivation and habit formation in the basal ganglia; and mood and cognitive flexibility in the brain stem.You may be one or a combination of these five primary brain types: (take this brain assessment to find out yours)Balanced: you have a very healthy brainSpontaneous: you have low dopaminePersistent: you’re often worried, rigid, and inflexibleSensitive: you need other people and isolation is hardCautious: your GABA levels are lowLearn more about brain types and what actually boosts your happiness according to neuroscience in Dr. Amen’s book, "You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type.”“Happiness comes from moving your life forward toward your life goals with meaning and purpose, based on your values, despite whatever obstacles are in your way,” Dr. Amen says. “A happy life doesn’t focus on the past with regret or look to the future with fear.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 909New Developments in Stem Cell Treatments – Dr. Harry Adelson & Dr. Amy B. Killen : 909
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Non-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesTasty Keto Bread & Chips: https://www.uprisingfood.com/DAVE, use code DAVE to get $10 off the starter bundleApple Cider Vinegar Benefits: https://paleovalley.com/DAVE, use code DAVE to get 15% off your first orderSPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Call the phone number listed on the Docere Clinics website: (435) 604-0438. Mention you heard about stem cell treatments on the Dave Asprey podcast and get half off a consultation.IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’re going to find out about Dave’s recent stem cell procedure and the newest technology stem cell medicine happening at Docere Clinics in Park City, Utah.Dr. Harry Adelson was one of the earliest adopters of the use of stem cells for the treatment of chronic musculoskeletal pain. His practice has offered 100% Regenerative Injection Therapy since 2002 and 100% stem cell therapy since 2010. He’s performed more than 6,000 stem cell procedures and invented the Full Body Stem Cell Makeover®, the most comprehensive stem cell upgrade currently available. His colleague, Dr. Amy B. Killen performs anti-aging and regenerative medical treatments. She’s fellowship trained in Anti-Aging and Regenerative Medicine through the American Academy of Anti-Aging Medicine. She’s also done extensive additional training in aesthetics, platelet rich plasma and stem cells, hair restoration, bio-identical hormones, nutrition, fitness and sexual health.Drs. Adelson and Killen performed Dave’s original Full Body Stem Cell Makeover®, which used Dave's own stem cells from his fat and bone marrow, as well as extracellular vesicles. This episode gets into new developments in stem cell treatments, like the advent of VSEL (very small embryonic-like stem cells) technology. Stem cells therapy may be right for you if you’re interested in:Better skinIncreased sexual performanceDecreased painImproved functional body movementPreventive aging treatmentSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 908Hacking the Gut Microbiome – Interventions With Dave – Tim Waters : 908
IN THIS EPISODE OF THE HUMAN UPGRADE™...… Dave talks with Tim Waters about ways to improve the health of his gut microbiome. A former wrestler, Tim spent years cutting weight. He experienced gall stones and eventually had his gall bladder removed 20 years ago. That led to long-term use of proton pump inhibitor pharmaceutical. Now over 50, Tim wants to wean off the pharmaceutical and heal his gut. He’s made some progress on his own but has some complicating factors at play.Here are a few things you'll learn in this “Interventions with Dave” episode:What causes low stomach acidThe difference between a proton pump inhibitor and an H2 blockerHow certain foods influence gastric refluxHow to manipulate your gut pH (acid and heat)The role enzymes play in digestionThe importance of bileThe benefits of butyric acidHow to get your good gut bacteria workingHow to check your methylationWhy tracking your blood pressure regularly is a great ideaThis conversation covers a lot of gut ground! Don’t miss Dave’s intervention recommendations in the “Links & Resources” section of the episode webpage: https://daveasprey.com/intervention-tim-waters-908/Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 907Form, Function & How to Fix Your Feet – Peter Francis, Ph.D. : 907
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Probiotic Eases Stress: https://www.omnibioticlife.com/DAVE/, use code DAVE20 to get 20% offCapture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideCARBON60 for Brain & Body: https://wizardsciences.com, use code DAVE for an exclusive discount on C60 productsSPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERSVivobarefoot is offering 100-day free trial on their footwear. Visit https://www.vivobarefoot.com/us/daveasprey and use code ASPREY20 for adult and kids’ shoes. You’ll get 20% off your first order.IN THIS EPISODE OF THE HUMAN UPGRADE™...…whether you’re hiking, climbing, working or playing, your feet ground you. Except when they don’t. Shoes don’t always match up to the function of your life. You can end up with pain and misalignment throughout your body when your feet are encased in shoes that don’t support your body’s natural biomechanics.Feet, for all their variety in shape and size, get the award for amazing. Your feet literally form the center of your body’s whole system of movement. Did you know these facts about the human foot?26 bones, nearly 30 muscles and thousands of nerve endings33 articulations (each with six degrees of freedom of motion) Humans began running about 2 million years ago to be able to hunt“If the foot moves normally, then the muscles start to work and so on and so on,” says Peter Francis, Ph.D. “It’s really just about allowing your foot to move as nature intended.”Peter joins the show from the Carlow Institute of Technology in Carlow, Ireland. There, he lectures in sport and health science and researches how modern environments effect human health and performance. With degrees in Sport and Exercise Science and Physical Therapy, and a PhD in Exercise Science, he’s written more than two dozen peer-reviewed journal articles and led numerous research projects. He’s also worked with teams and individuals at amateur, European and Olympic level. He knows feet! And, he’s got a lot to share about how feet influence the way your body moves. A runner himself, Peter studies the role of foot development with and without shoes. He then figures out what that means for movement skills and injury risk.Your feet are by their form and function incredibly sensory. When you block sensory information from your feet, you have trouble maintaining stability and balance.You may think that your shoes help support your feet, but the opposite proves true. Shoes strip your natural movement and make your feet weak.Your shoes, not your feet, are the problem.In this conversation, you’ll learn what footwear works best for you and your kids and the importance of variability and fun in your movements. Start with Vivobarefoot barefoot-style shoes to reap the benefits of living life barefoot (or close to it).See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 906How Uric Acid Disrupts Your Metabolic Heath – Dr. David Perlmutter : 906
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Structured PH-Balanced Alkaline Water: https://www.ameolife.com or call 1-8-0-0-4-2-2-8-1-4-8, use code DAVE20 to get 20% offMattress Temperature Tech: https://www.eightsleep.com/dave, use code DAVE to save $250 on the Pod ProIN THIS EPISODE OF THE HUMAN UPGRADE™...… guest Dr. David Perlmutter explains how he’s an expert in dropping acid, but not in the way you might think. A regular contributor to groundbreaking science, he’s back on the show to talk about why you should be paying attention to your uric acid levels. Dr. Perlmutter is a neurologist and five-time New York Times bestselling author. His books include “Brain Wash,” “Grain Brain” and “Brain Maker.” He’s recognized internationally as a leader in the field of nutritional influences in neurological disorders. Now, he’s turning his attention to how uric acid threatens your metabolic health.Uric acid is a waste product of metabolism, and its levels are a key health marker and indicator of chronic degenerative diseases. When uric acid levels rise, they tell your body to store fat, which messes with your metabolism and poses a danger to your health.Alcohol, purines (breakdown product of DNA and RNA in foods) and fructose (the kind of sugar found in processed foods) are the three main sources of uric acid. Since the days of our primate ancestors, we’ve lost the ability to break down uricase, so what we choose to consume makes a big difference.“If we can emulate those signals to our DNA and our physiology that have evolved to keep us healthy,” Dr. Perlmutter says, “we're going a long way to offsetting these incredibly powerful metabolic disruptions that are paving the way for the biggest cause of disease on our planet.”His newest book, “Drop Acid: The Surprising New Science of Uric Acid—The Key to Losing Weight, Controlling Blood Sugar, and Achieving Extraordinary Health,” includes ways to measure, control and track your uric acid levels and key strategies to manage them. You’ll find out the top five foods that raise uric acid (hint: fructose earns the No. 1 spot). You’ll also find out the five important supplements to take to lower your uric acid levels back into a healthy range.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 905Longevity Strategies To Use Right Now – Tony Robbins & Peter Diamandis, M.D. : 905
Organically & Biodynamically Grown: https://www.dryfarmwines.com/dave, get an extra bottle in your first box for just a penny. (Free shipping except Hawaii & Alaska.)TruKava Nature's Nootropic: https://trukava.com, use code DAVE15 to get 15% off8th Annual Biohacking Conference: https://biohackingconference.comIN THIS EPISODE OF THE HUMAN UPGRADE™...…Tony Robbins and Peter Diamandis, M.D., distill the knowledge, expertise and life’s work of more than 100 doctors, scientists, and Nobel Laureates. The world’s top experts in medicine, technology, and science show you what’s available right now. This means you can gain access to the tools that turn back your biological clock.Tony is an entrepreneur, best-selling author, philanthropist, and the nation’s No. 1 life and business strategist.Peter accelerates breakthroughs in products, companies, and industries to solve some of the world's greatest challenges. He’s a Harvard Medical School-trained doctor; founder and executive chairman of the XPRIZE Foundation; and executive founder of Singularity University.I wanted to have them on the show together to talk about what’s new and next level in biohacking and the incredible advances happening in health technology. They teamed up to write the new book: “Life Force: How New Breakthroughs in Precision Medicine Can Transform the Quality of Your Life & Those You Love.”The book lays out advancements in precision and regenerative medicine so you can increase your energy, improve your immune system, and extend the length and quality of your life.Tony’s own personal health issues and use of stem cells led him into the topics in this book. In less than a year using many of the advances he writes about, Tony reduced his biological age from 62 to 51.Coming in at nearly 700 pages, “Life Force” guides you through sections of easy-to-digest information and practical tips.The Life Force Revolution (how to make yourself the CEO of your own health)Heroes of the Regenerative Medicine Revolution (technologies changing every concept we think we understand about medicine)What You Can Do Now (ways to expand your physical and emotional energy)Tackling The Top 6 Killers (heart disease, stroke, cancer, inflammation and autoimmune disease, diabetes and obesity, Alzheimer’s disease)Longevity, Mindset & Fulfillment (exponential technologies driving longevity like genome sequencing, storage, computation and communications) Through this compilation by Tony, Peter and Robert Hariri, M.D., Ph.D., you’ll find out about powerful resources for healing, transformation and regeneration of the human body. You’ll accelerate your learning, dial up your performance and put into motion innovative ways you can live a longer life.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 904Hacking Menopausal Weight Gain – Interventions With Dave – Cheryl Fraser, Ph.D. : 904
IN THIS EPISODE OF THE HUMAN UPGRADE™... … Dave talks with Cheryl Fraser, Ph.D., about menopausal weight gain and ways to manage changing hormones and metabolic mayhem. As a Buddhist psychologist, sex therapist, author and speaker, Cheryl’s sharp, frank, and fearless. She’s also deeply frustrated about gaining weight during menopause that just won’t budge. She’s put on 15 pounds in the past five years. Despite doing various eating programs and being physically active, she continues to struggle with weight loss and metabolic stability.In this “Interventions with Dave” episode, you’ll learn about:Learned helplessnessLow DHEA Testosterone’s role in female healthAdrenal hormonesManaging cortisolKeto cyclingThyroid function influences energyThyroid supplements Meats high in Omega-6 Biohacks for lymphatic drainage & detoxUpgraded fitness hacksRed and infrared light effects on blood flow and nitric oxideRecovery benefits Keto Tracking: Get Your Mojo On With All Things Keto – Dorian Greenow – #824CAROL AI Bike Fitness: Shorten Your Cardio Time Even More with REHIT – Ulrich Dempfle – #834Lighting for Your Biology and Environment: https://truedark.com, use code DAVE to get 15% off “Fast This Way: Burn Fat, Heal Inflammation and Eat Like the High Performing Human You Were Meant To Be” Fasting Challenge“Super Human: The Bulletproof Plan to Age Backward and Maybe Even Live Forever”Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 902High Performance Requires Radical Adaptability – Keith Ferrazzi : 902
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!NAD+ for Brain Health: https://innovativemedicine.com/DAVE and save 20%Track Blood Glucose: https://www.levelshealth.com/DAVE, sign up for the Beta groupFranchise Opportunity: https://ownanupgradelabs.com, to check out the fitness center of the futureIN THIS EPISODE OF THE HUMAN UPGRADE™... …entrepreneur, biohacker and leadership expert Keith Ferrazzi says going with the flow of change, or even leaning into it, isn’t nearly enough. You’ve got to go for radical adaptability. He’s here to explain what it means and how you can use it for yourself and your business. “The essence of radical adaptability is that it is predictive, proactive, and progressive, very unlike the typical response to change, which is inherently reactive and conformist,” he says.Keith, an expert in relational and collaborative sciences, founded Ferrazzi Greenlight, a research institute that focuses on the impacts of behavioral science on business. He coaches Fortune 100 company leaders and executive teams. In that coaching, he teaches people how they can change their organizational behaviors to increase growth and value.“If you're in business, if you work in an organization or you're a leader of an organization, what you're going to hear from us today is, well, how do you need to reboot yourself so that you don't crawl out of the rubble and go back to old work ways, but you, what I call, don't go back to work, you go forward to work,” Keith says. “How do you leap forward 10 years out of the pandemic?”He addresses those questions in his new book, “Competing in the New World of Work: How Radical Adaptability Separates the Best from the Rest.” With equal parts vulnerability, authenticity and honesty, Keith walks you through how to become the best version of your career self. For example, he’ll talk about the importance of collaborating with your colleagues to focus on growth and learning, challenging your assumptions to build empathy and why without resilience you won’t make it far. You’ll also get a look into specific tools and apps that can help you build resilience from a distance, with trust.Keith talks about a “Go Forward to Work” project he led during the pandemic that documented best practices and innovations happening in the workplace. Here’s what he found: “The pandemic gave people courage to shoot through the shit and state the truth, because there was an emergency going on and we rose to an occasion, and we didn't give a shit about silos.”In a post-pandemic world, it’s absolutely necessary to master radical adaptability. If you’re looking for ways to catapult your career or organizations forward, and not get lost in the chaos of change, you don’t want to miss the knowledge and practical tips shared in this episode. Get Keith's Exclusive FREE Video CourseSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 901How Big Pharma Corrupts Medical Knowledge – Dr. John Abramson : 901
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Apple Cider Vinegar Benefits: https://paleovalley.com/DAVE, use code DAVE to get 15% off your first orderMattress Temperature Tech: https://www.eightsleep.com/dave, use code DAVE to save $250 on the Pod ProNon-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesIN THIS EPISODE OF THE HUMAN UPGRADE™...… you’ll learn about the harm of Big Pharma and the reasons why pharmaceutical drugs are becoming much more widely used than science or good health care justifies. Corporate interests and public good in America are often at battle, and the world of medical research and care is no different. Dr. John Abramson joins the show to explain what that means for your health and what you can do about it.Dr. Abramson is an expert on health care policy, inside and out. He’s taught at Harvard Medical School for 20 years and spent more than 20 years as a family physician. He’s researched, written about, and had unique access to the inner workings of the pharmaceutical industry for decades. He’s served as an unpaid consultant to the FBI and Department of Justice, and as an expert in national drug litigation. He’s also written a new book, “Sickening: How Big Pharma Broke American Health Care and How We Can Repair It.” He joins the show to talk about how big pharma controls research, withholds data and shapes information that medical professionals rely on to make important care decisions. He shares the stories behind four of the biggest failures in the pharmaceutical world that include deception, illegal practices, exploitation and lies. He’ll discuss how the job of pharmaceutical companies–no matter how effective a project may be–is to make a profit. It’s important to never forget that, Dr. Abramson says.Dr. Abramson offers ways you can put your trust back in science and take your health into your own hands in a world of corporate giants. Opening scientific data for independent analysis is a good start. This episode offers information so you're aware and you can make better decisions for yourself.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 900Sex Life Upgrade: Find a Style That Connects Your Body & Mind – Layla Martin & Mistress Natalie : 900
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Month of Love Gift: Give the sensation of a hug, deep relaxation and better sleep: https://balooliving.com/dave, use code DAVE for a special discountIsometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona PlusMust-Have Magnesium: https://magbreakthrough.com/DAVE, use code DAVE10 to get a 10 percent discountIN THIS EPISODE OF THE HUMAN UPGRADE™...… two experts with very different approaches to sex illustrate exactly how one size does not fit all. Sex is a uniquely personal choice. From the mystical to the unconventional, this podcast doesn’t shy away from candid conversations about sex. There’s a lot to learn. No matter what your life stage or circumstance, understanding how sex benefits your body and mind can dramatically improve your life. Layla Martin studied human sexuality and human biology at Stanford and then spent a decade learning from Tantric masters in the jungles of Asia. She combines modern science with the effective practices of Tantra to inspire people to heal trauma or shame and fully awaken their sexuality. As the founder of the Tantric Institute of Integrated Sexuality, Layla teaches people how to experience more epic sex and legendary love through her trademarked VITA™ Method.Mistress Natalie lives at the intersection of BDSM and biohacking, a unique (and pretty cool!) place to be. She’s spent more than two decades doing BDSM with her clients, specializing in kinky coaching, luxury domination and BDSM therapy. Along the way, she’s continued to evolve and research her field. She also earned certifications in life coaching, personal training and yoga. More recently, she’s explored the idea that practicing your kinks can lead to some serious performance upgrades. There’s more! If you liked this special episode with Layla and Mistress Natalie, listen to their full podcasts about sex. And check the “Links & Resources” section below for other info to upgrade the many aspects of your sexual wellness.Altered States of Sex – Layla Martin – #651Learn about Layla’s approach to epic sex and legendary love: https://laylamartin.comRead her special Dave Asprey blog article: Two Effective Practices for Sharing Your Sexual Desires With Your Partner50 Shades of Dave with Mistress Natalie – #341Learn about how Mistress Natalie’s uses sex as a biohacking tool (suitable for over 21): https://www.mistressnatalie.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 899How to Control, Reframe and Change the Chatter in Your Head – Ethan Kross, Ph.D. : 899
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Air Purification Solutions: https://hypoair.com/DAVE/, get 10% offCapture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideKickstart Autophagy: https://timelinenutrition.com/DAVE, use the code ASPREY10 to get 10% off any planIN THIS EPISODE OF THE HUMAN UPGRADE™... … you’ll find out how to harness the power of your inner voice to ease anxiety, improve physical and mental health, and deepen your relationship with others. “The mind is flexible, if we know how to bend it,” says psychologist and award-winning professor Ethan Kross, Ph.D., founder of the Emotion & Self Control Laboratory at the University of Michigan.He’s one of the world’s leading experts in controlling the conscious mind. He studies the ways in which your inner voice impacts your health, performance, decisions and relationships. He explores how people manage their emotions in order to better understand self-control. In particular, the conversations you have with yourself directly impact every part of your health and life.He explain that your inner voice functions to do things like this:Keep information active in your mindCoach you through problemsSimulate and plan aheadTell you storiesThat inner voice can be a powerful tool, giving you creativity, connection and definition. However, when the voice turns to negative and disorienting self-talk (chatter), it can create chaos and overwhelm by zooming into our problems, making you lose perspective.Ethan’s pioneering research mixes behavioral and brain research to get at the “why” behind human nature. He uses insights from his research to give people science-based tools they can use to change their behavior, be used in relationships, support a career move, improve physical performance, decrease stress, increase productivity and be used to reach life goals. You’ll use new tools like mental time travel, tough love and introspection.In this conversation about his new book, “CHATTER: The Voice in Our Head, Why It Matters, and How to Harness It,” you’ll learn: How social media plays a part in our chatterHow to zoom out with a flexible mind, changing thoughts and distancing ourselvesHow to use tough loveHow to teach your kids about chatter from a young ageHow to help your friends with their own chatter (and what makes it worse)With Ethan’s experience studying the conscious mind for 20 years, you can learn how to turn negativity into an awesome tool that helps you master your own self-talk.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 898When WTF Means Your Freedom’s At Stake – Dave Asprey : 898
bonusIN THIS *BONUS* EPISODE OF THE HUMAN UPGRADE™...Dave goes live – and solo – on Telegram to talk about the state of the world according to one of his four Fs: Freedom. (The others are fear, food and fertility). From your biology to your right to protest, freedom means you get to decide what’s right for you.“The need to be free is so you can perform your role in the greater organism, Dave says. "And this is why whenever we have central authority and central control, we end up with overreach. And when there is overreach, there is, universally, throughout all of human history, you push and you push and you push as a government until people lose it, and then they inevitably change things.”Website: https://daveasprey.comTelegram: https://t.me/aspreyofficialYouTube: https://www.youtube.com/c/daveaspreybprMembership: https://www.ourupgradecollective.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Mini-Episode: Cool Facts Friday #19
bonusCool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.3 things indicate whether you’ll look for information or remain ignorant Deadly anthrax toxin could be a new pain relieverMultiple break-ups and solitary living linked to inflammation in menInsects may be the next big thing in animal protein alternativesNerve cells in the brain suppress reproductive hormones when cortisol is too highStress before and during pregnancy alters infants' cellular agingSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 897Stay Sick or Eat Meat? Facing a Vegan Crisis – Monica Hershaft : 897
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Weighted Blanket Benefits: https://balooliving.com/pages/dave, use code DAVE to get a special discountBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultationSPECIAL OFFERS FOR THE HUMAN UPGRADE LISTENERS Virtual Event: Treat the Source®️: The Premiere Wellness Event for People with Chronic Symptoms. March 26, 2022, Register hereNew Patient Exam and Body Analysis Consult: https://monicahershaft.com/patients, use code DAVE75 at checkout to get $75 off IN THIS EPISODE OF THE HUMAN UPGRADE™...… Monica Hershaft brings an interesting perspective to the choices of living your life vegan, vegetarian or animal-centric.She grew up in a vegetarian, then fully vegan family. Her father, Holocaust survivor Dr. Alex Hershaft, co-founded the modern animal rights movement in the U.S. more than 40 years ago. She speaks to the ethical, moral and deeply traumatic reasons people choose veganism. Those points cannot be dismissed. Nor can the implications of a completely plant-based diet without animal protein on human health.Monica shares her story of being an active, athletic teen and continuing veganism into adulthood. It was a trendy detox program at age 34 that triggered her rocky, decade-long health journey from debilitating sickness to finding health solutions. “It didn't even occur to me as a child to think anything different because that's just how I was raised and that's how we ate,” she explains. “Eventually, when I did grow up and get sick, it took a while for me to even consider that it could be my diet. So, it was a very big pivot mentally to make that leap.”She also wrestled with coming out as Paleo to her father and what discarding veganism meant for her family relationships. “I had to be willing to lose the relationship, to stand up for what my truth was,” she says. Healing her physical and mental health led the hard discussions: “I'm going to be eating animal protein at every single meal, because I believe that that's how I can keep my life and my health,” she recalls saying. Monica’s now a bestselling author, motivational speaker, holistic health practitioner and nutritional consultant. She founded a top-rated holistic wellness center in Los Angeles and recently relocated to Scottsdale, AZ where she works 1:1 with patients to get their health back. She helps people heal from illness that other medical professionals often label a “mystery.” You’ll gain valuable information from this conversation, such as:how to assess your symptoms, how to understand nervous system switching and blocking,the important relationship between the vagus nerve and an allergic state,food checklists to follow, how to recognize harmful food propaganda,why fungus and metals are the big thing (in vegetarians/vegans),why animal welfare and good soil matters,educational videos to watch, programs to attend, and,how to find help from functional, alternative and holistic professionals.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 896Hype or Hope? Semaglutide Changes the Weight Game – Dr. Robert Kushner : 896
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!NAD+ for Brain Health: https://innovativemedicine.com/DAVE and save 20%Apple Cider Vinegar Benefits: https://paleovalley.com/DAVE, use code DAVE to get 15% off your first orderNon-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesIN THIS EPISODE OF THE HUMAN UPGRADE™...…you’ll learn about semaglutide, a new weight loss drug that’s been getting a lot of attention. Highly respected obesity expert Dr. Robert F. Kushner joins the show to talk about new research findings. He was part of a team that published semaglutide study results in the New England Journal of Medicine this past year. Looking into semaglutide, typically used for Type 2 Diabetes, showed that it also reduced body weight.We talk about how you might use semaglutide, both from an aging perspective and from a weight loss perspective. You look at risk reward for everything you can do, and then you decide what's going to work best for you. There's some interesting knowledge to be gained from the research on semaglutide.Here’s the short version of how it works: “Semaglutide mimics our naturally occurring hormone called GLP-1,” explains Dr. Kushner. “When you give it back to a person in pharmacologic doses or high doses, but it mimics what we normally have, it augments or highlights this feeling of, "You know what, I am really not as hungry as I was before. I'm more full than I was before, so I don't need as much food." It's actually the change in appetite that causes a weight loss that we see with this kind of a drug.”A clinician, educator and researcher, Dr. Kushner has spent his decades-long career on adult weight management for adults. Board certified in both internal medicine and nutrition, he maintains a medical practice, teaches students and medical professionals, and presents around the world. He’s written more than 250 original articles, as well as reviews, books and medical book chapters.He’s Medical Director of the Center for Lifestyle Medicine at Northwestern Medicine in Chicago; a professor of Medicine in the Division of Endocrinology and a professor of Medical Education at Northwestern University Feinberg School of Medicine.This episode’s conversation includes the role of lifestyle in weight management. It’s shortsighted to view semaglutide as a wonder drug isolated from diet, exercise and even mental health. It’s all related. And new understanding of obesity as a disease and its biological drivers helps the search for lasting solutions, including training for healthcare professionals.Listen on to find out more about semaglutide and six factors that might be causing your weight gain or making it difficult for you to lose weight.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 895Hacking Eyesight – Interventions with Dave – Mark Bell : 895
bonusEIN THIS EPISODE OF THE HUMAN UPGRADE™... … Dave talks with Mark Bell about eyesight and ways to approach vision problems. Mark is a world record-breaking powerlifter, the owner of Super Training Gym, The Strongest Gym in the West, and the inventor of the Sling Shot, a bench press accessory tool to help lifters add pounds to their bench press, help lift through injuries, and reinforce proper technique.He’s built a life and business based on high performance. So when he began experiencing worsening vision over the past several years, he wanted to know how he could improve it.“There's strength and there's flexibility,” Dave says. “And as you age, your eyes, the muscles lose strength. The tissues lose flexibility and this has to do with collagen types and cross linking of collagen. You're actually seeing yellowing of parts of the lens in your eye. And then, there's also a neurological thing where the brain may not actually be connecting.”In this “Interventions with Dave” episode, you’ll learn about:Effective supplements for eye health How mitochondrial health affects visionThe importance of morning sunlightEye exercises to restore ability to focus based on the Bates Method and Meier Schneider’s "Yoga For Your Eyes"Gabor patches to stress your brain's visual perception areaEye training using an app, like GlassesOff.Palming IV stem cellsMore about Mark BellWebsites: Mark Bell and Sling ShotPreviously on Bulletproof Radio: Bigger, Stronger, Faster: Powerlifter Mark Bell & HBO Filmmaker Chris Bell – #432Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 894Free to Choose: Your Guide to Personalized Longevity Medicine – Liv Health : 894
ESPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERSGet your first month of either the LIV Core or LIV Complete membership FREE and save 50% off initial lab work panel. No contracts! Details at https://livhealth.com/dave/ (Be sure to use .com not .org.) Liv Health telemedicine care currently is available across the U.S. Liv Canada will be operational in the coming months and international is in the works.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Air Purification Solutions: https://hypoair.com/DAVE/, get 10% offPEMF Therapy: https://www.haelo.com/dave, get more info and a free copy of “Fast This Way” by Dave AspreyBarefoot Footwear: https://www.vivobarefoot.com/us/daveasprey, use code ASPREY20 to get 20% off your first order and access to the VHealth Barefoot Movement online coursesIN THIS EPISODE OF THE HUMAN UPGRADE™...… you’ll learn about a new model of healthcare focused on personalized longevity medicine. This custom telemedicine solution uses your own data to reach goals you have for the quality and length of your life.Andrew Wax, an Integrative Health Specialist and Director of Clinical Care at Liv Health, joins the show to walk you through the Liv Health model that’s putting people in control of their own medical care.Do any of these statements apply to you?You consider yourself a biohackerYou’re looking for a greater degree of medical freedomYou want more customized care than you’re getting from your primary care doctorYou’ve been on a medical protocol and have stopped making progress or seeing results If you’re age 18 to 85 (and older) and want to target sleep, cognition, body composition, nutrition, fitness, hormones, immunity, or gut health – Liv Health’s precision medicine approach may be right for you.Andrew’s extensive experience includes working with patients and physicians to develop anti-aging and regenerative protocols. He’s earned multiple degrees in the areas of physiology, biochemistry, psychology, and a certificate of neuroscience. He’s certified in peptide therapies and is the former director of the Medically Managed Peptide Program at the Boulder Longevity Institute.He and the entire Liv Health team bring related education and experience to Liv Health, where care includes hormones, peptides, novel small molecule drugs, supplements, fitness, nutrition, and other lifestyle interventions. In short, Liv Health is goal-based medicine. You come in with a goal, and your Liv Personal Performance Team (PPT) creates the path to get you there. You get a step-by-step guide to custom-curated protocols and treatments based on your individual data. Your PPT includes a patient support coordinator, health concierge and doctor. It’s important to note that Liv Health services don’t replace general medical care from your primary care doctor. Consider Liv a supplemental service that helps you target particular longevity goals.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 893Ways to Build a Resilient Family – Joe De Sena : 893
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Isometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona PlusCapture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideIN THIS EPISODE OF THE HUMAN UPGRADE™...… One “Tough Mudder” Joe De Sena shares tips on how you can build mental toughness and resilience within your entire family.Over more than a decade of work, Joe De Sena built Spartan into the world’s leading endurance sports and wellness brand. He also created one of the most popular obstacle-race series in the world, Spartan Race. He’s convinced a community of more than 10 million people to voluntarily embrace the experience of “tough fitness.”“I want you to give me the worst stuff you got,” Joe says. “The turmoil, the pain, the suffering, and [then] give me the strength I need to deal with it. Just keep it coming. And so that became the Spartan prayer, like give me the shitty days, give me the failure, because I know I'm going to become better at dealing with that.”It’s not until you reach the edge and get through it that you realize how much you’re capable of. But does tough mean resilient? And does that level of influence translate to family dynamics? That’s the conversation we dig into specifically for parents and kids. Joe’s always had a passion for endurance and activities that push his mental and physical limits. During the pandemic, he looked closer to home and found ways he could be a better parent. He believes how you react to challenging situations defines you and your family.His latest book, “10 Rules for Resilience: Mental Toughness for Families,” talks about defining and creating resilience. “This book was born in 2020, while I watched as families all over the globe faced the discomforts thrust at them and realized how insanely unprepared most people are for difficulty.”During this time in our history, the pressure, stress and unpredictability in bigger amounts than ever made clear that it was essential to develop more resilience. Joe’s term, “True Resilience” describes a body and mind carved out of hard work, challenge, and failure. He says it takes True Resilience to approach overwhelming situations with calm and confidence, to not get rattled, anxious, or angry, and even to embrace failure, setbacks, and redirections.It also means listening and responding with intention: “Much of your success will depend on your ability to discern what sparks enthusiasm and motivation in your child,” Joe says. “Find your kid’s flow.”Here’s some of what you’ll find in “10 Rules for Resilience: Mental Toughness for Families:”Proven techniques from clinical research and experience to set the whole family up for better, more effective coping skills.Family activities that supplement each rule of resilience and help you put the reading material into real-life action.A values exercise to help your family create a solid vision statement.A five-step model to increase your fear IQ.Listen on as Joe shares the benefits of training your kids in hard work, traveling as a family, and pushing yourself to the limit as a parent. Note: Joe co-wrote “10 Rules” with Dr. Lara Pence, a clinical psychologist and Chief Mind Doc at Spartan.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 892Why Lying to Yourself Could be a Good Thing – Marisa Peer : 892
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Structured PH-Balanced Alkaline Water: https://www.ameolife.com or call 1-8-0-0-4-2-2-8-1-4-8, use code DAVE20 to get 20% offNon-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesMinerals for Cell Function: https://www.beamminerals.com, use code DAVE20 to get 20% offIN THIS EPISODE OF THE HUMAN UPGRADE™...…you’ll learn about a therapy method that gets to the root of your problem and solves it within one to three sessions. “The main reason it works, I believe, is that it overcomes the high level of resistance that most people have to changing fundamental beliefs about themselves by getting to the deepest core of their belief very quickly,” says Marisa Peer. Marisa is a clinical psychologist and expert in human behavior who developed a new way to approach your mental health — Rapid Transformational Therapy® (RTT®). RTT offers the same benefits of traditional therapy, but on a much quicker timeline.“I didn't understand why therapy, which is also dealing with pain, had to be so long. I never got that ‘turn up with your pain every week,’” she says. “We'll keep reopening the wound. And one day, you might get better.”She’s also an international best-selling author of multiple books, motivational speaker, personal development expert and leading celebrity therapist. She’s worked with people around the world and most of them have a story they tell themselves about not being “enough.” Her newest book puts the focus squarely on the personal narrative you’re clinging to: “Tell Yourself A Better Lie: Use The Power Of Rapid Transformational Therapy To Edit Your Story And Rewrite Your Life.” “After 30 years of private practice, I created Rapid Transformational Therapy (RTT) because it was clear to me that so much of the pain and suffering we see in the world comes down to the fundamental stories we tell ourselves and how often those stories are untrue or outright lies,” she explains. RTT has roots in hypnosis.Marisa helps people pinpoint the reasons behind why people want what they want, so they can actualize a meaningful life for themselves. She uses a solution-oriented technique that can make you mentally stronger, more confident and even more loving towards yourself. “He who hesitates is lost,” she says. “While you're waiting to write your book or start your company, someone else is going to come along and write that book and start that company. So, time is the one thing we don't have access of. And so, I think they'll always be people who like that long method [of traditional talk therapy] and a lot of people who don't like it. And I think we can definitely accommodate both.”It’s time to start telling yourself the truth about who you are. “Our greatest pain is caused by the lies we tell ourselves,” Marisa says. She offers candid advice on how to help you recognize the harmful story you tell yourself and how to change it to a better one.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 891Get Moving! Align Your Body, Align Your Life – Aaron Alexander : 891
IN THIS EPISODE OF THE HUMAN UPGRADE... … Body movement expert Aaron Alexander joins the show to talk about how to integrate healthy movement practices into your daily life.You’ve likely heard that sitting is the new smoking – well, good news: It’s not the sitting itself, but how you sit, that affects your well-being. In fact, all the ways you hold your body and move your body matters. Body language and how you move through space tells others how comfortable you are, how truthful and trustworthy you are, and more.Most of you have built up body movement around a collapse state, which can lead to physical and emotional pain. Aaron spent years traveling the world, discovering how other cultures defined and measured health and studying movement behaviors. He found that the healthiest cultures incorporate aligned movement and sitting styles into their day-to-day activity. Take walking for example. “When you're out taking a walk, it's like you are literally playing symphony of your physiology,” he says. “Walking is one of the healthiest things that a person can do–just going out and getting yourself into that contralateral motion, contralateral being just like walking pattern. As you're doing that, you're stimulating your brain function, you're also stimulating things like peristalsis and digestion and organ function.”Aaron is a manual therapist, using movement techniques inspired by yoga, martial arts, chiropractic skills and more. He also hosts the popular Align Podcast, and wrote “The Align Method: A Modern Movement Guide for a Stronger Body, Sharper Mind, and Stress-Proof Life,” which shares the tools you need to reshape your environment for enhanced creativity and longevity.Healthy movement incorporating play and adaptability enhances creativity, resilience and creates a healthy nervous system. During the show, Aaron goes over the five daily movements to integrate into your life and how to get started in a productive, gentle and playful way.“Your body is so darn adaptable that if it's just a matter of you need to give it a baseline of the raw components to be healthy,” says Aaron. “If for a moment you're slouching over a chair, I love that. There's no problem with that, it's the repetition of that. If for a movement you're looking into a wall or into a blue light or whatever, you're not going to just explode.”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 890Recalibrate Yourself with Quantum Energy – Philipp Samor von Holtzendorff-Fehling : 890
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Weighted Blanket Relaxation: https://balooliving.com/DAVE, use code DAVE for a special discountApple Cider Vinegar Benefits: https://paleovalley.com/DAVE, use code DAVE to get 15% off your first orderKickstart Autophagy: https://timelinenutrition.com/DAVE, use the code ASPREY10 to get 10% off any planSPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERShttps://leelaq.com, use code DAVE10 to save 10%IN THIS EPISODE OF THE HUMAN UPGRADE...… you’re going to learn about quantum energy and the science behind how and why it works.Philipp Samor von Holtzendorff-Fehling founded Leela Quantum Tech to further develop and share the power of quantum energy. Quantum energy fields are different from harmful EMFs you’re told to avoid. Here are a few of the benefits of quantum energy, also known as “frequency medicine.”Improves your blood and cellular healthIncreases your fitness level and speeds up recovery Intensifies the taste of your food and extends its shelf lifeEases pain and activates your own inner healerImprove the quality of your water at home and on the road.Helps you become more resistant to stress and more efficient in your daily tasksPrevents exhaustion so you’re able to focus betterAllows you to worry less and enjoy the momentBut how can quantum energy and specific frequencies have such a powerful effect on humans, animals and even plants? Philipp looked to science for the answers. Leela submits its products to be scientifically studied by third party institutes and doctor’s offices. Leela concentrates pure quantum energy in specific plates and aligns them to create a highly concentrated field and quantum energy space. Examples are the Leela Quantum Bloc and Infinity Bloc. They’ve also developed frequency cards, capsules and clothing.“There's so many people that may want to enjoy support like that, and they don't understand it,” Philipp says. “And for them, you need to provide something for the brain to read through it, and that's what we've done.” So far, the research studies found quantum energy frequencies:Block, neutralize and bring EMFs into harmony Positively impact the autonomic nervous system and heart rate variabilityPositively impact organ function, cellular health and blood healthNeutralize harmful frequencies like herbicides, pesticides and cesium 137Boost body and energy function in 100% of cases Some of that testing includes measuring EMFs or using dark-field microscopy to measure voltage in the cells. Leela’s other research projects are studying the benefits of quantum energy frequencies for autistic kids, athletes, and people experiencing chronic Lyme disease.This fascinating topic gets into other frequencies, too, like molecular, etheric, and sound. Listen on to find out how you can use the power of energy frequencies to upgrade yourself.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 889How Neuroinflammation Disrupts Your Immune System – Gary Kaplan, D.O. : 889
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Mattress Temperature Tech: https://www.eightsleep.com/dave, use code DAVE to save $250 on the Pod ProMust-Have Magnesium: https://magbreakthrough.com/DAVE, use code DAVE10 to get a 10 percent discountProbiotic Eases Stress: https://www.omnibioticlife.com/DAVE/, use code DAVE20 to get 20% offIN THIS EPISODE OF THE HUMAN UPGRADE...… you’ll learn about neuroinflammation and its connection to the immune system from integrative medicine pioneer Gary Kaplan, D.O. The conversation gets into many topics like the immune system, infections, chronic disease and why your brain may be on fire. It’s all connected!Dr. Kaplan is a pro at alleviating chronic pain and illness in the field of integrative medicine, by combining integrative and alternative strategies. Conventional thinking about chronic pain and depression is flawed, he says, as more research shows often those symptoms are rooted in inflammation in the brain. Three major causes of inflammation include environmental factors, childhood trauma, and epigenetics and genetics.Inflamed brains, specifically, cause mental, emotional and physical pain like depression, anxiety, chronic fatigue syndrome, chronic fibromyalgia, pediatric neuropsychiatric disorders and more, he says.Dr. Kaplan’s treats patients at the Kaplan Center for Integrative Medicine he founded in 1985. He’s board-certified in Family Medicine, Pain Medicine, and Medical Acupuncture. He’s also studied and practiced Osteopathic Manipulative Medicine, Emergency Medicine, Herbal Medicine and is certified in Chelation Therapy.Virtual Conference Zeros in on Neuroinflammation Dr. Kaplan’s drawn on his interest in brain inflammation, the immune system and chronic disease to assemble experts from around the world. This group will share new developments and research about chronic illness at a virtual conference in February 2022.The conference topics will cover brain inflammation due to immune dysregulation. You’ll also hear about new breakthrough data on diagnosis and treatment of long-hauler Covid. It’s open to the public and healthcare professionals.“Symposium on Autoimmune Encephalopathy Secondary to Infectious Disease: A New Perspective on the Pathogenetic Interaction of the Immune system, Infection and Chronic Disease”Feb. 9, 10, 11, 2022Early bird pricing = $69 before Jan. 10. Regular pricing = $99 after Jan. 10Webpage: www.hopehealingknowledge.comLanding Page (with agenda & speakers)RegistrationSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Upgrade Your Metabolic System with the Right Foods – Dr. Robert Lustig – Best of 2021
bonusWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Vascular System Protection: https://arterosil.com/DAVE/, get 30% off and protect your blood vessels from vulnerable plaquePowerhouse Mushrooms: https://lifecykel.com/, use code ASPREY25 to save 25%Upgrade Digestive Health: https://globalhealing.com/dave, use code DAVE15 to get 15% offIN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… … Dr. Robert Lustig’s knowledge about the metabolic system landed with listeners in a big way.He’s a New York Times bestselling author of several books about the problems caused by sugar, processed food and the health conditions of obesity. In his latest book “Metabolical: The Lure and the Lies of Processed Food, Nutrition, and Modern Medicine,” he focuses on how real food can reverse chronic disease and promote longevity. He also challenges the current healthcare paradigm and the influence of Big Food, Big Pharma, and Big Government. “I wrote Metabolical to basically explain what is healthy,” Dr. Lustig says. “And based on the empiric data, based on the science, based on the pathologies that I describe in the book that belie chronic disease, I distilled all of the information down to six words – two precepts, six words: ‘Protect the liver, feed the gut.’”These are the eight cell pathologies that underlie all chronic disease, according to Dr. Lustig:glycationoxidative stressmitochondrial dysfunctioninsulin resistancemembrane instabilityinflammationepigeneticsautophagy"[When] you look at the entire molecular mechanism of every single one of those eight subcellular pathologies, none of them have a medicine," he says. "None of them are druggable. They're all foodable." His book also documents how processed food has impacted human health, the economy, and the environment over the past 50 years. “It’s not about obesity, it never was,” Dr. Lustig says. “The key to the kingdom is that it is not about obesity, it is about metabolic dysfunction and anyone can get it, and that’s what makes it a public health crisis, because obesity is a result of the problem, not the cause.”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Upgrade Your Energy with a Hormone-Gut-Immune Trifecta – Dr. Amy Shah – Best of 2021
bonusWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Nature’s Nootropic: https://trukava.com, use code DAVE15 to get 15% offStop Junk Light: https://truedark.com and use code DAVE to get 15% off glasses for adults & kidsImprove Your Home Biome: https://homebiotic.com/dave/ to get 15% offIN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™…… Dr. Amy Shah’s approach to managing energy struck a chord with listeners.Dr. Shah, a double board-certified physician, searched for a complete mental, hormonal, and inflammatory reset after she experienced a car accident and personal energy crisis.And while she uses an integrative and holistic approach to wellness in her medical practice, what she learned about energy and fatigue connected a lot of dots.Regulating the “energy trifecta,” made up of balanced hormones, a well-functioning gut, and a healthy immune system, makes all the difference. (She’s also an expert in circadian rhythm fasting.) “These three areas communicate, and they talk to the brain constantly,” says Dr. Shah, who studied and trained at Cornell, Columbia, and Harvard Universities. “And if any of those are broken, then you're going to be tired. And so things like short fasting, circadian fasting, sinking with nature and circadian rhythms, which is our internal clock and eating the right foods really can make a difference. And of course, there's this whole component of mind, body health, which we sorely miss in Western culture.” What you eat, when you eat and mind-body health rule your energy patterns and likely could be the root cause of your fatigue. She lays out solutions in her book, "I'M SO EFFING TIRED: A Proven Plan to Beat Burnout, Boost Your Energy, and Reclaim Your Life."See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 888Kindness: The Win-Win Superpower – Jamil Zaki, Ph.D. & Leon Logothetis : 888
bonusWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Kratom for Energy, Focus & Pain Relief: https://superspeciosa.com, use code DAVE to get 20% offUpgrade Digestive Health: https://globalhealing.com/dave; use code DAVE15 to get 15% offMore Meditation in Less Time: https://40yearsofzen.comIN THIS EPISODE OF THE HUMAN UPGRADE...… the conversation centers on what kindness is, how to practice it, and why it matters. Kindness is a powerful tool – it helps people feel less alone and truly makes the world a more joyful and tolerant place. The two insightful guests you’ll hear from in this episode – Jamil Zaki, Ph.D., and Leon Logothetis – will leave you feeling lighter, more optimistic and, well, kinder!Jamil Zaki, Ph.D., uses tools from psychology and neuroscience to help you understand how empathy works. As a professor of Psychology at Stanford University and the director of the Stanford Social Neuroscience Lab, he explains how kindness is a learnable skill. You can use it in your life more often.Jamil’s kindness research includes empathy and compassion to form a triad. “Kindness is a behavior that benefits another person,” he explains. Scientists view empathy like a big umbrella term for emotional connection and then compassion as one of the components of emotional connectedness to others.You can dive into more of his research in his book, “The War for Kindness: Building Empathy in a Fractured World.”Leon Logothetis invites you to join the kindness rebellion. He’s certain you’ll find wealth in health and happiness, success in inner peace and a definite cool factor in being kind. Leon’s a motivational speaker, adventurer and philanthropist known as the “The Kindness Guy.” His travels take him all over the world looking for and spreading kindness (binge watch both seasons of “The Kindness Diaries”). He speaks to children and adults at schools and companies about the importance of being kind in the world. Empathy and compassion have a lot to do with that.Check out his latest book: “Go Be Kind-A Life-Changing Little Journal: 28½ Adventures Guaranteed to Make You Happier,” to find out how you can get in on the kindness movement.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 887How to Build Your Emotional Agility and Resilience – Susan David, Ph.D. & Joan Rosenberg, Ph.D. : 887
bonusWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Powerhouse Mushrooms: https://lifecykel.com, use code ASPREY25 to save 25%Track Your Health: https://info.insidetracker.com/dave, sign up to get your promo code for 25% off storewideSupplement Bioavailability: https://www.quicksilverscientific.com, use code DAVE15 to save 15% on your first order IN THIS EPISODE OF BULLLETPROOF RADIO...…you’ll learn that being adaptive to change is a skill you can cultivate. One of the most sustainable ways to keep going with the flow is knowing how to build emotional awareness. These two guests give tips on managing your emotional states so you can be more resilient in all areas of your life.Expert psychologist, trainer and speaker Joan Rosenberg, Ph.D., guides yoou to achieve your highest potential by teaching you how to be in control of your own emotions. Award-winning Harvard Medical School psychologist Susan David, Ph.D., describes all the psychological skills necessary for you to thrive in uncertain times. She challenges the common attitude that you have to “fix” your difficult emotions through positive thinking. “Emotional agility is about the capacity to be with ourselves,” Susan says. “That includes our difficult thoughts and emotions and stories and past experiences in a way that's compassionate and curious and that doesn't hold us back from being the people that we most want to be.”Since you can’t get away from emotions, there’s power in knowing how to deal with them. “We've got to be able to reconnect with ourselves so that we can move forward in the world,” Susan says.Get ready to learn some foundational skills that will make you an emotional agility pro.About Joan: The author of “90 Seconds to a Life You Love: How to Master Your Difficult Feelings to Cultivate Lasting Confidence, Resilience, and Authenticity,” teaches you how to be in control of your own emotions.Joan guides you through eight unpleasant feelings she’s pinpointed: sadness, shame, helplessness, anger, vulnerability, embarrassment, disappointment and frustration. She says the best way to approach these feelings is with confrontation and empathy.“The single most important thing I can do is to recognize someone’s pain, and just in essence, hold a mirror up to it, even if it sounds like you’re saying the things that are so obvious,” Joan says. “It has a huge impact of calming someone else’s nervous system down.”About Susan: She’s the author of “Emotional Agility: Get Unstuck, Embrace Change, and Thrive in Work and Life,” based on 20 years of research of how to get through uncertainty “For people to be healthy with themselves, with the inner worlds, these are not soft skills,” Susan says. “These are the most fundamental skills that we can have as human beings.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Mini-Episode: Cool Facts Friday #18
bonusEIn this Episode of The Human Upgrade™...Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.Beer & blue cheese found in ancient fecesBlood marker detects dementia earlyTeam flow shows up as a unique brain stateTrauma-focused psychotherapy works for PTSDMDMA improves PTSD symptoms EPISODE SPONSOR: All your cells require minerals to function. Fulvic and humic complexes provide cellular nutrition to support detoxification. Go to https://www.beamminerals.com and use code DAVE20 to get 20% offLISTEN: "Follow" or "subscribe" to The Human Upgrade™ with Dave Asprey on your favorite podcast platform.REVIEW: Go to Apple Podcasts at daveasprey.com/apple and leave a (hopefully) 5-star rating and a creative review.FEEDBACK: Got a comment, idea or question for the podcast? Submit via this form!SOCIAL: Follow @thehumanupgradepodcast on Instagram and Facebook.JOIN: Learn directly from Dave Asprey alongside others in a membership group: ourupgradecollective.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 886Erectile Dysfunction: Causes, Solutions and Why It’s Normal – Dr. Paul Thompson : 886
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Sleep Better on Natural Memory Foam: https://myessentia.com, use code DAVEVIP to get an exclusive discountControl Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentSubscription Box for Biohackers: Each season (and limited editions, too!) discover and enjoy innovative wellness products, hand-curated by Dave Asprey, that you may not find anywhere else. https://daveaspreybox.comSPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERSVisit https://getmyphoenix.com/dave and use code DAVE100 to save $100.IN THIS EPISODE OF THE HUMAN UPGRADE™… …urologist, surgeon and age medicine specialist Dr. Paul Thompson discusses the challenges men can experience with their sexual health, energy and performance. Erectile dysfunction happens to men at all ages and is actually quite normal. Causes can be physical, and hormones play a role. Nutrition or exercise habits may be culprits. And state of mind factors in.Dr. Thompson shares his clinical expertise on how getting to the root of what’s going on with men's sexual functioning will not only improve erectile dysfunction but also support other critical areas of men’s health. The conversation looks at the pros and cons of eating meat, what your cholesterol numbers really mean, and why cardiovascular health matters at every age.Guys, listening to this, if your doctor isn't asking you for Lp-PLA2, which is an enzyme that's expressed when there's damage to your arteries, then you have a problem. If they aren't looking at C-reactive protein, you have a problem; and if they're not looking at homocysteine, you have a problem. So, you could ask your doctor for them or you could ask your doctor, “Hey, what do you know about these?”You’ll also find out why oral health is so important and why you have to pay attention to your nitric oxide production.Dr. Thompson talks about the at-home device he helped develop at Launch Medical (he’s chief medical officer there) that's pioneering a solution for erectile dysfunction. It’s based on clinical acoustic wave therapy treatment. “Acoustic wave is really simple and it works, and it has to do with the growth of blood vessels,” he explains. The Phoenix device helps men improve and/or restore their sexual functioning.Guys and women who love guys or guys who love guys, this thing is real technology. It does work, it is not too good to be true, and it's worth talking about.This conversation takes any embarrassment or shame out of the ED equation and gets into the details of plaque, blood flow and how you can find a fix and reclaim your sexual health.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 885The Stress-Sleep Connection That’s Keeping You Up at Night – Dr. Dave Rabin : 885
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!High-Performance Leadership: https://www.humanpotentialinstitute.com/coach-training/Track Your Health: https://info.insidetracker.com/dave, sign up to get your promo code for 25% off storewideSupplement Bioavailability: https://www.quicksilverscientific.com, use code DAVE15 to save 15% on your first order SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERSVisit https://apolloneuro.com/DAVE10 to get 10% off an Apollo Neuro device.IN THIS EPISODE OF THE HUMAN UPGRADE™…...you'll learn about the impact of chronic stress in humans, how it wrecks your sleep and what you can do about it.For more than a decade, neuroscientist, board-certified psychiatrist, health tech entrepreneur and inventor David Rabin (an M.D. and Ph.D.) has been immersed in the science of stress. He’s been researching causes and ways to manage it. He’s also been helping people deal with the consequences of both acute and chronic stress.He’s back on the show (don’t miss episodes #729 and #730) to talk about how stress disturbs systems of your body and mind, which, of course, affects your sleep.Stress is not inherently bad because we require it to grow, Dr. Rabin says. “We require the stress to help us learn how to overcome the challenges that are signaled by the stress to become better, stronger, fuller versions of ourselves.” … “There are the situations where we start to see acute stress that can be healthy and very helpful to growth turn into chronic stress,” he continues. “And that chronic stress increases inflammation on a daily basis. It’s that chronic stress that increases likelihood of disease.”Dr. Rabin co-founded Apollo Neuroscience, a company that developed the first scientifically validated wearable technology that actively improves energy, focus and relaxation. This tech uses a novel touch therapy that signals safety to the brain. In new studies, it’s had a terrific impact on stress and sleep.“Health means the restoration and maintenance of balance for all of us,” Dr. Rabin says. “Critically important is managing our sleep and our circadian rhythms, and our sleep and wake cycles. Maintaining sleep and making sure we do things to have a healthy sleep rhythm is going to maximize our performance and energy availability during the day and psychedelic medicines and wearables can play as important to role in that for us as the day-to-day practices of breathwork and meditation, yoga, exercise and nutrition.”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 884Hacking Longevity Starts with Detoxification – Chris Shade, Ph.D. : 884
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Get Salty AF: https://drinklmnt.com/dave, get the LMNT sample pack for the cost of shipping, $5. (If you like it, try the new limited edition Mint Chocolate flavor for the holidays!)Unlock Your Brain with Customized Nootropics: https://nootopia.com/dave, use code DAVE10 to save 10% on your first order Track Blood Glucose: https://www.levelshealth.com/DAVE, sign up for the Beta groupSPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERSGo to https://www.quicksilverscientific.com and use code DAVE15 to save 15% all products.IN THIS EPISODE OF THE HUMAN UPGRADE™… … Christopher Shade, Ph.D., joins the show to take you through a new six-spoke “longevity wheel.” You’ll find out what you can do to live longer by managing toxins and hormones that influences aging.With expertise in environmental sciences, chemistry and biology, he founded the Colorado-based company Quicksilver Scientific. It’s a group of “chemists, biohackers and age rebels.”He specializes in the biological, environmental, and analytical chemistry of mercury in all its forms. He presents and teaches in the U.S. and nationally about mercury, environmental toxicities, neuroinflammation, immune dysregulation, and the human detoxification system.He's designed detoxification protocols, unique supplement delivery systems, and a patented mercury speciation test. As CEO, he continually drives development and innovation. Right now, the focus is longevity with a foundation in detoxification.Everyone has a meaningful amount of metals, plastics, molds or other toxins in their body and is pretty much operating with low-grade toxicity. And even though everyone has the same basic detoxification system, people react to and process toxins very differently. There’s a general universe of toxins: You have exogenous toxins from outside the body (metals, chemicals, mycotoxins or food-borne toxins). Then you have endotoxins, which are made on board usually by gut bacteria and lipopolysaccharide.That’s why cellular level detoxification matters so much. Bile flow, and knowing what blocks it and what opens it, plays a huge role in your body’s detoxification process.If you learn to think like a computer or especially a network engineer, there's a whole bunch of interrelated systems. If one of them is broken, it'll have an effect on the other. But when you look at detox pathways, you look at aging, it's a very similar mindset, way more so than you would think.Hormones, too, get in on the aging action. DHEA and pregnenolone are the mother hormones. All the other hormones are made out of those two things. “Hormones are necessary for all the detox reactions,” Chris says. “Having the right levels of all the hormones just powers everything up.”The six-spoke “Longevity Wheel” framework that Chris developed biohacks conventional aging assumptions. This wheel is a collection of biochemical pathways, mechanisms, and molecules that impact aging. Each spoke builds on another and all work together. Nrf2 and AMPKNADSirtuinsTelomeresSenolyticsNeuroendocrineListen on to find out more about how detox, hormones and the spokes of this new Longevity Wheel can impact how you age.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 883Toss the Candles! Biological Age Is Your New Birthday – Ryan Smith : 883
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Nature’s Nootropic: https://trukava.com, use code DAVE15 for 15% offSupport Immune & Digestive Health: https://justthrivehealth.com, use code ASPREY to get 15% offEat Good Keto Bread: https://www.uprisingfood.com/DAVE, use code DAVE to get $10 off the starter bundle. That includes two superfood cubes and a four pack of freedom chips!SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERSYou can order TRUAGE at https://trudiagnostic.com/dave-asprey and enter code ASPREY at checkout for $50 off.IN THIS EPISODE OF THE HUMAN UPGRADE™… …you’re going to discover how old you really are by taking a dive into the science of epigenetic methylation and biological aging. You’re going to find out about gene function, gene expression and what it has to do with how you age—and why it matters.Biochemist Ryan Smith co-founded TruDiagnostic, a company focused on methylation array-based diagnostics for life extension and preventive healthcare. TruDiagnostic, a CLIA certified lab and health data company, developed the TRUAGE anti-aging test. From a small blood test, TruDiagnostic can tell you your biological age—how old your body acts, based on how it’s functioning (as opposed to your chronological age, which is the number of years you’ve been on Earth). Biological age is one of the most impactful pieces of data you can have about yourself. Age is the number one predictor of death, and your biological age matters more than the number of times you’ve been around the sun. For example, you could be 42, and if you take great care of yourself, your biological age may be 30… Or, if you take poor care of yourself, your biological age may be 60. Either way, TruDiagnostic will tell you how old you really are. And their test goes further than that. After you discover your biological age, TruDiagnostic also gives you a list of strategies to reverse aging based on your unique genetics. In other words, you get personalized anti-aging biohacks—and you can test your age over time to see if you’re getting younger, so you know whether or not your anti-aging hacks are working.If you can turn back the clock on your biological age, you unlock the door to a longer, better life. It feels like the cusp of a big change in longevity research with science and data now more fully supporting this work. TruDiagnostic currently has over 30 approved clinical research studies underway investigating how epigenetic methylation changes impact how long you live and how well you age.In this episode, you’ll also learn:Why men age worse than women, and what you can do about itThe best ways to predict your biological age (hint: grip strength is one of them)How getting COVID changes the speed at which you ageWhy small amounts of stress are amazing for anti-aging (and the right ways to stress your body and brain so you age in reverse)See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 881A Bacteria That Guards Your Gut Lining – Colleen Cutcliffe, Ph.D. : 881
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Cardiovascular Health: https://arterosil.com/dave20/, get a 3-pack and save up to 30% plus free shippingHealth Upgrades with Custom Lab Testing and Your Data: https://get-base.com/DAVE, use code DAVE to get 20% off your first month of membershipTrack Blood Glucose: https://www.levelshealth.com/Dave, sign up for the Beta groupSPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERSGo to https://pendulumlife.com and use promo code DAVEVIP to get an exclusive discount. IN THIS EPISODE OF THE HUMAN UPGRADE™… …we get into the gut. If you’ve listened to my podcast before you probably know how much the gut is a culprit in disease. I’ve invited experts on the show to explain how without the right balance of good bacteria in your gut, you can have inflammation, poor immune response, GI distress and much more. Your gut lining is like a fence, explains Colleen Cutcliffe, Ph.D. It needs maintenance and attention, because that “fence” is what guards your gut from bad bacteria and toxins. Without it, you lose a strong defense system.That’s where Akkermansia comes in. This bacterial strain naturally found in the gastrointestinal tract helps regulate the mucus lining of the gut, while also fine-tuning immune responses. Only in recent years have people understood (and acted on) the gut microbiome’s role in wellness or disease. Dr. Cutcliffe shares the research behind Akkermansia and why this probiotic is changing the gut health game.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Mini-Episode: Cool Facts Friday #17
bonusIn this Episode of The Human Upgrade™...Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.Migraines diminish the quality of your deep and REM sleep.Microbiome bacteria can either help or harm people with Type 2 Diabetes.A safer contraception option for men means no testicle injections.Kids learn to manage big emotions by playing specially designed video games..New studies show 6.5 hours of sleep could be surprisingly good for you.EPISODE SPONSOR: Control Blood Glucose with Pendulum. Visit https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment.LISTEN: "Follow" or "subscribe" to The Human Upgrade™ with Dave Asprey on your favorite podcast platform.REVIEW: Go to Apple Podcasts at daveasprey.com/apple and leave a (hopefully) 5-star rating and a creative review.FEEDBACK: Got a comment, idea or question for the podcast? Submit via this form!SOCIAL: Follow @thehumanupgradepodcast on Instagram and Facebook.JOIN: Learn directly from Dave Asprey alongside others in a membership group: https://ourupgradecollective.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 880Alzheimer’s Targets Women’s Brains Decades Before Symptoms Show – Maria Shriver & Dr. Lisa Mosconi : 880
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Cut Your Cardio: https://carolbike.com, use code DAVE to get $100 off your orderNervous System Recovery: https://apolloneuro.com/dave10 to get 10% off an Apollo Neuro deviceUpgrade Your Magnesium: https://magbreakthrough.com/DAVE, use code DAVE20 to get 20% off. You’ll also get FREE bottles of BiOptimizers’ best-selling products with select purchases. Exclusive discount through November 30, 2021.IN THIS EPISODE OF THE HUMAN UPGRADE™…… you’ll find out how Alzheimer’s impacts women more often than men and how symptoms begin decades before you think they do. Six million people in America are experiencing Alzheimer’s. Two-thirds of them are women. My guests, Maria Shriver and Dr. Lisa Mosconi, are championing an increase in research, raising awareness and providing resources about this topic to find out why. The Alzheimer’s spotlight falls twice yearly because it’s just that important: November for National Alzheimer’s Disease Awareness Month and National Family Caregivers Month, and June for Alzheimer’s and Brain Awareness Month. A lot of the research happening to understand Alzheimer’s can benefit everyone. It can teach you how to lessen inflammation in your brain and get a handle on or prevent immune and metabolic brain disease. When you learn how to do that, you unlock cognitive performance and longevity. Maria and Dr. Mosconi offer some great insight and practical tips.Maria Shriver is a champion of Alzheimer’s awareness. For two decades she’s been reporting, writing and fundraising for it, specifically relating to how it impacts women. She founded the The Women’s Alzheimer’s Movement, a nonprofit that brings together doctors, researchers and brain experts to support Alzheimer’s research, clinical trials, and information sharing. It also provides public education, prevention tips and tools for brain health.“I think what happens is that there are small moments along the way that we all disregard,” Maria says. I think the challenge to be present in our own lives is a challenge, really, for all of us. The challenge to take note of our health is a challenge for all of us.”Dr. Mosconi is a neuroscientist and neuro-nutritionist focused on brain science, the microbiome and nutritional genomics, specifically the early detection of Alzheimer’s. Her research on women’s neurological health has changed the way science approaches the female brain. She speaks to the more than 10 years of research that shows Alzheimer’s starts with negative changes in the brain years – if not decades – before any clinical symptoms emerge.“It’s really important to take care of ourselves, and our brains are really one of our most important assets,” Dr. Mosconi says. “And the best way to engage in prevention is now. It's never too late to start, but the sooner we start doing it, the better.”Learn even more about how Alzheimer’s affects women and what to do about it:Maria Shriver On Why Alzheimer’s Is A Woman’s Problem – #497The Women’s Alzheimer’s MovementThe Shriver Report: A Woman’s Nation Takes on Alzheimer’sWomen, Menopause and Alzheimer’s: XX Brain Connections with Lisa Mosconi, Ph.D. – #675lisamosconi.com“The XX Brain: The Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer’s Disease”“Brain Food: The Surprising Science of Eating for Cognitive Power”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 879Temperature Hacking for Better Deep and REM Sleep – Matteo Franceschetti : 879
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Support Immune & Digestive Health: https://justthrivehealth.com, use code ASPREY to get 15% offTrack Your Health: https://info.insidetracker.com/dave, sign up to get your promo code for 25% OFF storewideMeasure Brain Function: Learn more and get a special discounted package at https://wavimed.com/, use code DAVESPECIAL OFFER FOR THE HUMAN UPGRADE™ LISTENERSGet Your Sleep Temperature Right: Go to https://www.eightsleep.com/dave to save $250 on the Pod Pro mattress padIN THIS EPISODE OF THE HUMAN UPGRADE™……you’re going to learn a bunch of brand new sleep hacks, taken from over a million nights of sleep data. Those hacks will come from my guest Matteo Franceschetti. Matteo defines high performance—having been a professional skier, high-level tennis player, competitive race car driver and practicing lawyer. He didn’t get much sleep doing all those things, so he co-founded Eight Sleep and set out to create and advanced sleep improvement device so he, and everyone else, could sleep better and perform better.We can all agree: “Sleep is a pillar, a fundamental pillar for your health,” Matteo says.Eight Sleep tracks biomarkers that measure your sleep quality. Then it uses machine learning to make automatic adjustments to your sleep environment. This helps you optimize your sleep, get the reset and recovery your body needs, and well, wake up feeling better than you have in years. Best of all, you don’t actually have to do anything. You just go to sleep, exactly like you did last night, and the technology does all the sleep hacking for you. TIME Magazine named Eight Sleep one of its “Best Inventions” of both 2018 and 2019, and Fast Company listed it as one of the most innovative companies of 2018. They’re a sleep hacking company making big inroads into understanding and regulating your body’s temperatures while sleeping. This affects your REM sleep the most.“While you are in REM your brain deactivates all the temperature controls in the body,” Matteo explains. “It doesn't let you fall into REM if it's too hot or too cold because you could potentially die. Changing the temperature based on your sleep stages and the different stages of the night is fundamental to maximize your deep and REM stages.”And Eight Sleep has a fix for that.“Based on your sleep stages and based on your biometrics, we adjust your body temperature during the night,” Matteo says. “It's not that we are inventing the wheel. Your body is already changing temperature during the night. It's part of your physiological process. We just enhanced that process to maximize your sleep performance.”And then I wanted to know, “How many hours of sleep per night do you think you can save people, by just changing temperature?” The point isn't necessarily to get less sleep, but it's to live more. Right? If you just got everything you needed and it was as good as what you have today, but you had enough time to do two hours of reading or learning every day or meditating or parenting or whatever else, it's not about working more necessarily. It's just about living more. It’s exciting to talk to Matteo because he brings a whole bunch of new biohacking ideas to the table, er bed. He and I get into a bunch of sleep topics during this conversation, including:How you can instantly increase your deep sleep by 40%, starting tonightHow you can reset your energy levels in the morning just by regulating your sleep temperature at nightHow you can compress sleep down to 5-6 hours a night, while actually getting more rest and recoveryWhy sleep consistency matters (and is still the hardest thing for people to do, well, consistently}Why machine learning is the future of personalized healthIf your sleep could use an upgrade, check out this episode for hacks you can implement right away and learn about what’s next in sleep technology. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 878How to Deal with Toxic People (Including Yourself) – Robert Greene : 878
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Supplement Bioavailability: https://www.quicksilverscientific.com, use code DAVE15 to save 15% on your first order Find Out Your Biological Age: https://glycanage.com, use code DAVE to get 20% off testing packagesNature’s Nootropic: https://trukava.com, use code DAVE15 for 15% offIN THIS EPISODE OF THE HUMAN UPGRADE™…… my guest fits right into the podcast transition to The Human Upgrade because he gets into the grittiness of what humans can do to level themselves up. No. 1 New York Times bestselling author Robert Greene shares science-backed knowledge about human nature.You know you want to be more powerful, more in control and excellent at what you do.Robert’s insights help you do just that. He gives you actionable tips that help you unlock limitations you may be putting on yourself so you can move your life upward and forward. (Similar to something I like to tell my team is great momentum: “up and to the right.”) World leaders, military generals, business executives, philosophers, and hip-hop moguls alike revere Robert’s books.After writing about mastery and power for more than two decades, he’s now become a TikTok sensation and the universal truth for a new generation. He’s one of my favorite authors who’s profoundly influenced my own life and been on the podcast twice before. Both episodes are must listens: The 48 Laws of Power – #380 and The Laws of Human Nature – #575. I asked him back to talk about his latest book: “The Daily Laws: 366 Meditations on Power, Seduction, Mastery, Strategy, and Human Nature.” “In “The 48 Laws of Power,” I talk about deception and con artists,” Robert says. “But in The Laws of Human Nature, it's almost about self-deception, how we're con artists with ourselves, how we create an image of ourselves as being morally right, being a good person, being intelligent, being rational, being empathetic. Whereas in fact, we're usually quite far below that ideal. … Because your default position is to always look externally and blame other people.”In “The Daily Laws,” he distills the best of his previous books and never-before-published material in to one amazing life guide for you. He lays out themes for each month of the year: Power, seduction, persuasion, strategy, human nature, toxic people, self-control, mastery, psychology, leadership, adversity and creativity. Within these themes he features a “daily law” for you to follow.“By not looking at ourselves in an honest way, and glossing over our own flaws and weaknesses, we become trapped in patterns of behavior that we cannot control,” Robert says in his new book. “As the years go by, and the misreadings, missteps, and unrealistic decisions pile up, we can become bitter confused, and damaged.”“The Daily Laws” is designed to reverse [these] toxic patterns and reconnect you to reality,” Robert says. “It takes aim at the various delusions we have all absorbed and seeks to attune your mind instead to the most entrenched traits of human nature and how our brains actually operate.”Listen on for the truth bombs.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 877How Postbiotics Upgrade Your Mitochondria – Dr. Anurag Singh : 877
SPECIAL OFFER FOR THE HUMAN UPGRADE™ LISTENERSGo to https://timelinenutrition.com and use code UPGRADE10 to get 10% off the Urolithin A subscription plan of your choice.IN THIS EPISODE OF THE HUMAN UPGRADE™……I’m going down a rabbit hole of exciting scientific research and clinical studies supporting Urolithin A’s influence on your mitochondrial health. The short version? Urolithin A stimulates mitophagy and renews your mitochondria. Specific big things to know? It upgrades your cells, your strength levels and offers pretty powerful anti-aging benefits.And a fun thing to know? The origin story of Urolithin A has to do with beavers. (!)To find out the basis of Urolithin A and its relationship to pomegranates, check out my previous podcast featuring two experts on the subject: How to Get Fitter Cells, Stronger Muscles and a Longer Life – Timeline Nutrition with Dave Asprey – #772.This time, I’ve invited Dr. Anurag Singh to the show. His expertise lies in clinical development and translational research. That means he translates new discoveries in science into real-world stuff you can actually use. He’s worked for several consumer health and biotech companies; authored more than 30 articles for top science journals; and designed and led more than 40 clinical trials over the last 15 years. As Chief Medical Officer of Amazentis, the parent company of Timeline Nutrition and the maker of Mitopure, a Urolithin A product. “A lot of times in the nutrition world, people put extracts and blends of probiotics together and they just give it to healthy people and expect magic to happen,” says Dr Singh. “Here, we've actually done the deep dive of the signs and how this molecule hits mitophagy and mitochondrial health. Then, bringing it to human translation and commercialization. This is really the holy grail for real world evidence.”He’s spent seven years focused on Urolithin A research and clinical trials. His initial round of research with Urolithin A showed that it could increase aerobic endurance and increase grip strength. Urolithin A also is the first postbiotic shown to repair mitochondrial health via mitophagy. Mitophagy is the process of renewing your mitochondrial growth as you age. As healthy mitochondria get older they accumulate free radicals and reactive oxygen species. They lose shape and stop communicating with one another, too. These faulty mitochondria have need to be replaced. Urolithin A revs up the mitochondrial recycling.Dr. Singh explains how you can get the benefits of Urolithin A and how to take it to achieve results.“Our gut microbiome is very complex ecosystem with hundreds of millions of different species interacting with each other,” explains Dr. Singh. “They need to be interacting in perfect harmony to release these postbiotics, which is the way I look at it is the perfect gut health relationship within the microbiome. So it's not one bacteria. It's not one strain that you can isolate and give. It's really got to be multi-species. I think you can probably conceptually find that strain or probiotic that could do it, but the process will be so inefficient that the best way is to short circuit it and provide the postbiotic, which is Urolithin A, directly in a pill or in a food product.” Another direction for Urolithin A is sports performance. Amazentis teamed up with renowned researcher Dr. Louise Burke in Australia to look into how Urolithin A affects mitochondrial health in athletes. Those results will be available in 2022.The future of Urolithin research keeps going in exciting new directions, including brain health. “So, there's a lot of research going on around this molecule,” Dr. Singh says. “[The] Buck Institute of Aging in California just got a multimillion grant from the National Institute of Health to study the effects of Urolithin A on the cognitive aging and how it can reverse some of the neuronal circuitry to look youthful. So we are actively looking at it and keeping our eyes and ears open for exactly feedback like this because brain cells also after muscle cells have the highest number of mitochondria that decline with aging.”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 876The Best and Worst Foods for Your Metabolic System – Dr. Casey Means : 876
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Control Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentSupport Immune & Digestive Health: https://justthrivehealth.com, use code ASPREY to get 15% offNervous System Recovery: https://apolloneuro.com/dave10 to get 10% off an Apollo Neuro deviceA SPECIAL OFFER FOR THE HUMAN UPGRADE™ LISTENERSThe Levels closed beta program includes a waitlist of more than 140,000 people. Skip that line and participate in the early access program with this link: levels.link/dave. Levels is available only in the U.S.IN THIS EPISODE OF THE HUMAN UPGRADE™…… you’re going to learn how to upgrade your metabolism and optimize your diet for your unique biology. Dr. Casey Means started her career as a surgeon, where she saw firsthand, day after day, the devastating long-term consequences of poor metabolism, from cardiovascular issues to cancer. She decided to refocus her career on helping people prevent metabolic disease in the first place, instead of treating the results. So, she began researching the causes of metabolic disorders. She quickly discovered a bigger and more subtle problem existed than she’d even realized. “A recent UNC study estimated that 88% of American adults have at least one biomarker of poor metabolism,” she says. “And this is likely part of the reason why nine out of 10 of the leading causes of death in the U.S. are related to, or worsened by, dysregulated blood sugar levels.” What does this lead to? “Healthcare costs are going up each year...and we’re getting sicker, fatter, and more depressed,” Dr. Casey says. That’s why she co-founded Levels Health. Levels created a wearable device that continuously monitors your blood sugar levels, then gives you a personalized nutrition dashboard based on the results. Blood sugar imbalances are a strong predictor of inflammation and long-term metabolic disease. Keeping your blood sugar on an even keel is a powerful way to gain stable energy all day, keep your metabolism running strong, and even lose weight. Everyone’s metabolism is different, which is why Levels uses your personal data to make food recommendations. It can tell you which foods to eat, which ones to avoid, the best times to eat, and even whether you’re eating too much or not enough. I’m a big believer in quantifying your health. When you have objective numbers about your biology, you can start to tweak things and make them better.Levels gives you the power to measure your blood sugar throughout the day—and Dr. Casey hopes that this kind of insight will help you eat better, lower your inflammation, supercharge your metabolism, and become a stronger, more capable version of yourself. In this episode, you’ll also learn about:The worst foods for your blood sugar (quick preview: Chick-Fil-A and Coca Cola are at the top of the list)How your metabolism affects everything from Alzheimer’s to acne to erectile dysfunctionWhy the calories-in-calories-out model of nutrition is flawedSimple changes you can make to build a stronger metabolismAnd much more!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 875Mattress Smarts 101 for High-Performance Sleep – Jack Dell’Accio : 875
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!High-Performance Leadership: https://www.humanpotentialinstitute.com/coach-training/Ozone for Healing, Cognition & Performance: http://www.drsozone.com/asprey, use code UPGRADED10 to save 10% on Dave’s Bulletproof BundleEat Good Keto Bread: https://www.uprisingfood.com/DAVE, use code DAVE to get $10 off the starter bundle. That includes two superfood cubes and a four pack of freedom chips!A SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE™Go to www.myessentia.com/daveasprey. Use promo code DAVEVIP for a special discount. IN THIS EPISODE OF THE HUMAN UPGRADE™……you’re going to learn how to revamp your sleeping environment and get awesome sleep. If you aren’t hacking, tracking, and prioritizing your sleep, it’s time to start. Sleep is a pillar of high performance that affects pretty much everything you do. If you want to perform at your best, you have to get deep, restorative sleep. You know that, but are you doing it?I’ve interviewed many sleep experts on my podcast. (Psst… I even created a 14-Day Sleep Challenge that teaches you how to hack your sleep.) This interview, however, is a bit different. I’ve invited a new kind of sleep expert on the show.Jack Dell’Accio spent the past 16 years studying mattresses. He set out to hack every aspect of mattresses, from pressure relief to posture support to toxin-free materials. You know that plastic, chemical smell that fills your bedroom when you get a new mattress? That’s caused by off-gassing—a combination of volatile chemicals that turn into gas and fill the air in your bedroom as you break in your mattress. Research has found that many off-gassing chemicals are respiratory irritants and can cause you to develop chemical sensitivities[*][*]. They’re nasty compounds and you don’t want to spend eight hours a night breathing them in. That’s where Jack comes in. After years of research, Jack created a new type of memory foam – a natural rubber latex-based foam – that provides support and pressure relief, without the off-gassing irritants that you find in old school memory foam. Jack founded Essentia, the first mattress company that uses materials that are good for your body, your health, and your environment. It’s a major upgrade over memory foam, both in terms of sleeping experience and chemical content. Essentia manufactures its mattresses and sleep products in its own GOLS (Global Organic Latex Standard) and GOTS (Global Organic Textile Standard) certified organic factory. These are the two most important certifications when it comes to organic mattresses and organic mattress manufacturing. They’ve also had their mattresses tested by experts at Johns Hopkins.In today’s episode, you’re going to learn the science behind building a better mattress, and why upgrading your mattress will improve almost every aspect of your body and brain. Jack and I also cover:The many chemicals hiding in cheap mattresses Why, thanks to a backwards California law, most mattresses contain several pounds of flame retardant chemicals (and how Essentia makes their mattresses without those chemicals.)Why 25% of NHL players use Essentia mattressesThe connection between cheap mattresses and chemical sensitivitiesHow Essentia created a proprietary EMF barrier foam formulaHow a high-quality mattress makes your brain work betterA sleep surface has to have six key elements to establish a sleep environment that regenerates the body during sleep. Essentia mattresses score at the top of all six. Here’s what to look for:Temperature Control (natural thermoregulation/ active cooling)Allergy Friendly (allergen-friendly materials)Accelerated Recovery (support and pressure redistribution)Optimized Sleep (adaptive accelerated response to reduce movement interruptions)Organically Clean (clean, non-toxic materials & an organic mineral formula that drives EMF patterns)Proper Posture (eliminates negative space to properly support the back)The mattress you sleep on matters just as much as all the other high-performance lifestyle choices you make. In this episode, you’re going to learn the science behind building a better mattress and why so many professional athletes choose Essentia.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 874Finding Joy, Building Community and Raising Your Own Pork – Radha Agrawal : 874
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Grounding Gear for Your Feet: https://harmony783.com/pages/dave, use code DAVE20 at checkout to get 20% off all grounding footwear and socks.Non-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesGet Salty AF: https://drinklmnt.com/dave, from unflavored to flavor-burst watermelon to classy combos like mango chili.IN THIS EPISODE OF THE HUMAN UPGRADE™️... …you’re going to learn how to biohack joy—and why it’s simpler, and more necessary, than you might think.Radha Agrawal is an author and successful entrepreneur with a singular purpose: to bring people together through joy and genuine human connection.She’s the founder and CEO of Daybreaker, a morning dance, music, and wellness movement that spans five continents. Through Daybreaker, Radha has built a community of more than 500,000 people across the globe who wake up early to dance together.She’s also co-founded, sold, and invested in multiple nine-figure businesses in the wellness space. MTV named her “one of eight women who will change the world,” and she recently toured with Oprah, bringing live music and dance to more than 150,000 people.One of the things Radha has learned over the years is that, for all the superficial connection available in the Digital Age, people are starving for true community—and real human connection seems to be harder to come by now, not easier.Radha thinks one of the biggest things we’re missing is vulnerability.“Every single person listening right now has a backpack full of their own history,” she says. “So, we all carry around this invisible backpack with all of our history in it. [With real community], you start pulling out, ‘My father died in an accident,’ or, ‘this happened,’ or, ‘I got betrayed by this person.’ All of a sudden, there's a depth of tenderness...that’s where community starts.”She goes deeper into the importance of human connection in her book, “Belong: Find Your People, Create Community, and Live a More Connected Life.”This conversation meandered through several unexpected topics, too. Listen on to learn:How to hack your brain for more joy (and how to quantify the joy in your life) – all backed by scienceWhy drugs are a poor substitute for human connection How to build true community in the Digital Age Why dance and music are the future of medicine How Radha went from a small idea to an enormous, successful company—without a single investor The bittersweet reality of being a pig farmer How pain and tragedy can make you stronger, not weaker The importance of forgiveness (and why we have to stop cancelling people) By the end of this podcast, you’ll have practical tools to become a more joyful person. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 873You Control Your Own Karma – Sadhguru : 873
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Nervous System Recovery: https://apolloneuro.com/pages/dave10, sign up to get 10% off an Apollo Neuro deviceSupplement Bioavailability: https://www.quicksilverscientific.com, use code DAVE15 to save 15% on your first order Upgrade Your Magnesium: https://magbreakthrough.com/DAVE, use code DAVE20 to get 20% off. You’ll also get FREE bottles of BiOptimizers’ best-selling products with select purchases. Exclusive discount through November 30, 2021.IN THIS EPISODE OF THE HUMAN UPGRADE™️... Sadhguru, a yogi, mystic, visionary and spiritual master who spreads wisdom around the world, clarifies the meaning of karma (no, it’s not a checklist of good and bad deeds) and explains how much you’re in charge of your own karma. His most recent book, “Karma: A Yogi’s Guide to Crafting Your Destiny,” breaks down the ways in which karma frames our lives.“It’s time to unpack the most overused, abused and yet indispensable world in the spiritual vocabulary of the world,” says Sadhguru in his book. “It is time to examine how karma is connected to some of the most vital areas of human inquiry: the meaning of life and above all, how to live it.”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Mini-Episode: Cool Facts Friday #16
bonusIn this Episode of The Human Upgrade™...Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.Examining the relationship between autoimmunity and pain.Plants up regulate their own autophagy to bring nutrients back in balance.How autophagy supports stressed-out cells.New genes found! Nearly three times more cause obesity than prevent it.EPISODE SPONSOR: Trigger autophagy with Spermidine. Visit https://spermidinelife.us/dave and use code DAVE25 to get 25% off your first month’s order.LISTEN: "Follow" or "subscribe" to The Human Upgrade™ with Dave Asprey on your favorite podcast platform.REVIEW: Go to Apple Podcasts at daveasprey.com/apple and leave a (hopefully) 5-star rating and a creative review.FEEDBACK: Got a comment, idea or question for the podcast? Submit via this form!SOCIAL: Follow @thehumanupgradepodcast on Instagram and Facebook.JOIN: Learn directly from Dave Asprey alongside others in a membership group: https://ourupgradecollective.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 872Discover Your ‘Sparketype’ and Meet Your True Self – Jonathan Fields : 872
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Mattress Temperature Tech: https://www.eightsleep.com/dave, use code DAVE to save $250 on the Pod ProControl Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentHealth Upgrades with Custom Lab Testing and Your Data: https://get-base.com/, use code DAVE to get 20% off your first month of membership.Support Immune & Digestive Health: https://justthrivehealth.com, use code ASPREY to get 15% offIN THIS EPISODE OF THE HUMAN UPGRADE... If you find yourself deeply questioning parts of your life that you haven’t before, you’re not alone. People are asking more existential questions about their lives than they were two years ago, and Jonathan Fields joins the show to guide you through some answers.Jonathan maximizes human potential, especially in the realm of meaningful work. He’s the bestselling author of four books on self-development, most recently “Sparked: Discover Your Unique Imprint for Work that Makes You Come Alive.” He also hosts the popular Good Life Project podcast.“I started into this topic two decades ago,” Jonathan says. “The fact that the last two years have dropped literally the entire world into the biggest existential questioning in generations is not something that I saw coming. But we are in that place, as we sit here depending on the research that you look at, anywhere from 25 to 50 percent of people either have quit their jobs or are in the process of quitting or seriously considering it.”He aims to help people realign the work they’re paid to do, with the actual work that nourishes them through something called Sparketypes. They’re the 10 different archetypes that are sparked by different kinds of work. You may be a maven, maker, scientist, essentialist, performer, sage, warrior, advisor, advocate or nurturer.https://sparketype.com/sparketest/.Get started with the Sparketype quiz at Once you determine your particular Sparketype, it can be easier to find work that lights you up. Knowing your Sparketype also can lessen the fear of a career pivot and show you how to take your enthusiasm for one passion into a different line of work. You then can confidently build a career with a sense of purpose and direction.“[People] may not know what the bargain is that they want to step into,” Jonathan explains. “But what they're getting clear on is the fact that the way that work has made them feel has satisfied certain needs, for sure, security, safety. The more existential needs, which tend to really become more important when we get a little bit further in life, those have generally been set aside. Part of that bargain was maybe later. Later is here.”Enjoy the show!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 871Moving Through Fear’s Allure to Find Inner Peace – Akshay Nanavati : 871
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Measure Brain Function: Learn more and get a special discounted package at https://wavimed.com/, use code DAVESleep Better on Natural Memory Foam: https://myessentia.com, use code DAVE25 to get 25% off any mattressNon-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesIN THIS EPISODE OF THE HUMAN UPGRADE...Akshay Nanavati’s story of perseverance includes overcoming drug addiction, alcoholism that pushed him to the brink of suicide, depression and PTSD from fighting in Iraq with the U.S. Marines.“That's when I fell in love with the experience of adversity and the struggle because boot camp was terrifying,” Akshay says. “Everything about [it] was terrifying but it was so alluring that I started to look for other ways to confront myself—ultimately to go to war with myself.” He believes that the path to inner peace is the pursuit of a worthy inner war. He went on to build a global business, run ultramarathons, conduct humanitarian work in post-conflict zones, and explore some of the most hostile environments on the planet—from mountains to caves to polar icecaps. “Nature became my playground to explore my fears and ultimately, systematically push through them one inch at a time.”“I craved a high I believed I could only get by living on the edge of life and death,” he says in his book, “Fearvana: The Revolutionary Science of How to Turn Fear Into Health, Wealth and Happiness.” He’s also spent years extensively researching neuroscience, psychology and spirituality. He combined his life experience with that research to write “Fearvana” and infused it with ways to transform fear, and its counterparts stress and anxiety, into something much more positive. His Holiness the Dalai Lama wrote in the book’s foreword, “Fearvana inspires us to look beyond our own agonizing experiences and find the positive side of our lives.” Akshay now teaches people how to overcome their own fears and how to tap into their brain’s superpower—neuroplasticity.Sounds good, but how do you really move through stress and attain growth? First, you have to learn to disidentify with fear and suffering by remembering you are not your thoughts, feelings or experiences, Akshay explains. “You are simply the one who experiences them. Through this process it becomes so much easier to create a life of fulfillment, It’s a lifelong practice and a great pathway to growth.”You can even learn to "suffer well" in the day-to-day context of your human experience.“I couldn't care less when fear shows up,” he says. “What matters to me is what I do with it once it does. I can let go of the construct I have around the fear and accept it for what it is and then choose what I want to do outside of it.”Take a listen for more tips on how to become fearless. Akshay heads to Antarctica in early November 2021. Learn more about his South Pole journey and how to follow along here. Enjoy!Got a comment, idea or question for the podcast? Submit via this form.Be sure to follow or subscribe to The Human Upgrade with Dave Asprey on your favorite podcast platform so you don’t miss an episode!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 870It's Time for an Evolution: The Human Upgrade with Dave Asprey : 870
Across 10 years and nearly 1,000 episodes, this podcast elevated what you knew about the capabilities of your mind and body.Now, I’m evolving it even further in my plan to upgrade humanity.I invite you to Expand Knowledge, Explore Performance and Embrace Possibility with The Human Upgrade.You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable.People from around the world who elevate what it means to be human. People who choose danger when it's worth it. Just like you. What are you going to learn from these people in the domains of your biology, your body? What are you going to learn about your mind, your thoughts, your habits, the way you show up in the world, and what are you going to learn about the spiritual side of things? The personal development side, that weird space where you wake up and there's a dream in your mind. What does it mean?You can't just focus on one if you want to be an upgraded human. You upgrade all of them. You start with your hardware. Because when your body works right, you have enough electricity. When you have enough electricity, then you can handle the things in your life that need handling. And you can say, "Well, I have some energy left over. What will I do with it?"Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.Join me on this next evolution to upgrade your mind, body and life. Enjoy! Got a comment, idea or question for the podcast? Submit via this form.Be sure to subscribe to follow or subscribe to The Human Upgrade with Dave Asprey on your favorite podcast platform so you don’t miss an episode!Web: daveasprey.com/Instagram: instagram.com/dave.asprey/Facebook: facebook.com/Daveaspreyofficial/YouTube: youtube.com/c/DaveAspreyBPR/featuredSubscription Box: Dave Asprey BoxMembership Group: The Upgrade CollectiveBlog: Dave Asprey BlogPodcast: The Human Upgrade with Dave AspreySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 869Tap Into Your Brain’s Full Potential – Patrick Porter, Ph.D., with Dave Asprey : 869
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Track Your Health: https://info.insidetracker.com/dave, save 25%Nervous System Recovery: https://apolloneuro.com/dave10 to get 10% off an Apollo Neuro deviceOzone for Healing, Cognition & Performance: http://www.drsozone.com/asprey. Use code UPGRADED10 to save 10% on Dave’s BundleSPECIAL OFFER FOR BULLETPROOF RADIO LISTENERSDiscover how to upgrade your brain fitness: https://braintap.com/daveIN THIS EPISODE OF BULLETPROOF RADIO... You’ll find out how award-winning speaker and author Dr. Patrick Porter developed tools that help your brain access its optimum state through brainwave entrainment. Brainwave entrainment means that different sounds, like Binaural Beats and Isochronic Tones, are pulsed into each of your ears to stimulate your brain into an altered state of consciousness. In a good way! This can improve your focus, energy, relaxation and deep sleep.Using guided meditation, Dr. Porter’s BrainTap device uses a neuro-algorithm to synchronize your brainwaves to a specialized sound. That results in full-spectrum brainwave activity. Each session ensures the brain’s ability to reorganize itself by forming new neural connections, also known as neuroplasticity.Dr. Porter has been a leader in brainwave entertainment tech for more than three decades years. He previously developed the world's first personal sound and light brain-training machine, the mc2, and created a Behavior Repatterning device. He’s written several books about the brain, including: Awaken the Genius: Mind Technology for the 21st Century; Discover the Language of the Mind; Thrive in Overdrive: How to Navigate Your Overloaded Lifestyle; and Awaken Your Flourishing Brain.Dr. Porter continues to widen the scope of what we know about brain capabilities and performance. He says,” We've got this globally world-class brain that can do incredible things for us,” but people often aren’t listening to it.“Once we started being able to measure the brain, we could track how the brain changes,” he says. “We know that every three to five seconds, we need to make a change or interrupt the pattern. If not, the brain will go “bye-bye,” – it's like advertising. The brain only has so much.”BrainTap increases your production of neurotransmitters, leading to a more balanced brainwave state. Even if you can’t stay in that balanced brain state, the feeling of that optimal mode will stick with you and will be within reach at all times. It’s like a flow-state from meditation if you’ve experienced that. But you don’t have to be a meditation expert to experience benefits. BrainTap allows even complete beginners to see immediate progressYou can do the BrainTap sessions at different times of the day when you naturally lose energy, helping you with things like sleep, focus, concentration, mindfulness, memory, stress and anxiety. The sessions also have been shown to increase athletic performance and recovery, and even help with addictions.In this episode, Dr. Porter explains the four elements of BrainTap, including Binaural Beats, Guided Visualization, 0-Cycle Holographic Music and Isochronic Tones. You’ll get to geek out on all the ways your brain affects your body (and vice-versa) and learn what you can do to reach your full brainiac potential. “Our brain actually is always syncing to its environment,” Patrick says. “That's why if it's chaotic {that it’s] causing some disruption. You have to filter it out. You have to learn how to do that.” Don’t miss Dr. Porter’s IG Live! Hacking Your Brain with Light and Sound.Enjoy! Got a comment, idea or question for the podcast? Submit via this form.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 868Be Your Own Hero: Take Risks, Face Your Fears and Choose Courage – Ryan Holiday with Dave Asprey : 868
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Solve Sitting: https://us.harmonidesk.com/, use code DAVE20 and get $20 off any standing deskInfrared Sauna Benefits: https://www.sunlighten.com/DAVE. Call the number on the website and mention “Dave Asprey” to get $200 off a cabin sauna, $100 off a Solo system, and free shippingNon-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesIN THIS EPISODE OF BULLETPROOF RADIO... you’ll discover what it takes to be courageous and heroic in your own life.The Spartans used to build temples to fear. They did so to keep fear close, see its power and ward it off. Modern-day philosopher Ryan Holiday is here to tell you how to do that in your own modern life by using courage to overcome fear.“You can have that reaction [to fear], but then you also realize, if you don't act on it, if you push through, there's often something on the other side of it,” Ryan says. “Or you realize that the more you expose yourself to it, the less scary it is each time and the less perhaps even that you feel that thing.”Everyone experiences fear, but those who can learn to go beyond it will find room for courage. His most recent book, Fear is Calling: Fortune Favors the Brave is compelling and empowering. It breaks down what it means to confront fear, courage and heroism in order to discover your own grace and wisdom. We talk about how to transform fear into courage and the power of choosing the relationship you have with fear.“Man, people get really uncomfortable when something that they were told by their parents, or their church, or their society, or their social media, and all of a sudden, they face profound evidence that it's not true,” Ryan says.Pulling stories from some of the greatest humans in history he talks about how heroism can change the world, and how history can help guide you through contemporary phenomena rooted in fear, like cancel culture and government mandates. This is the first book in Ryan’s new series on the four virtues of the ancient world: courage, temperance, justice, and wisdom. Don’t miss Ryan’s previous visit to Bulletproof Radio and the discussion about stoicism and ego: Modern Stoicism & Crushing your Ego: Ryan Holiday #527Enjoy! Got a comment, idea or question for the podcast? Submit via this form.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 867How Measuring Brain Function Leads to Performance Upgrades – David Oakley, Ph.D., with Dave Asprey : 867
SPECIAL OFFERS FOR BULLETPROOF RADIO LISTENERSMeasure Brain Function: Learn more and get a special discounted package at https://wavimed.com/, use code DAVEWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Non-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesRevitalize Your Mitochondria: https://www.timelinenutrition.com, use code ASPREY10 to get 10% off the plan of your choiceEat Good Keto Bread: https://www.uprisingfood.com/DAVE, use code DAVE to get $10 off the starter bundle. That includes two superfood cubes and a four pack of freedom chips!IN THIS EPISODE OF BULLETPROOF RADIO... I talked to the co-founder of WAVi at the 7th Annual Biohacking Conference in Orlando, Florida. Physicist David Oakley created a device that’s used to directly measure brain function and gives you a 360-degree assessment of your brain performance.WAVi is an all-in-one measurement platform. Users get objective information about brain function through EEG, visual ERP, auditory ERP, heart rate variability (HRV), Trail Making, standard assessments and more. This full FDA-regulated Class II device measures biomarkers of your brain with detail and precision in under 15 minutes.“People measure their weight every day, right?” David says. “Step on the scale, “Where am I at today?” So, we should be measuring our brains regularly. Someday there will be WAVi in doctors’ offices and you’ll check your brain like you check your weight.”For an introduction to WAVi, listen to Bulletproof Radio episode #619: Your Brain Voltage: Measure It, Raise It, Control It. In this interview, David and I go really deep into the science behind WAVi’s development. We get into physics, neuroscience, brain data, scientific inquiry and what’s exciting about the future of brain performance research. David comes from a long family line of inventors and creators. His own career as a physicist includes research and teaching at universities. He was also a researcher at the Los Alamos National Laboratory and has analyzed data within neutrino astrophysics, a branch of astronomy that observes astronomical objects with neutrino detectors in special observatories.He has published research and articles in the areas of physics, medicine, and art. At mid-life he turned to brain data and created WAVi: a mix of art, science, commerce, and public service.He made the move to study the brain when he met a fellow scientist David Joffee. “He started showing all the [brain] patterns, and I thought, “This is beautiful,” David says. “It's beautiful waves. You can do a lot with it. You can help people. It's about the same as physics, though. It's the same, just voltage versus time series data.”David’s now exploring multiple brain topics, including concussions, Alzheimer's, Dementia, and mental health.You’ll also find out why P300 continues to be an important signature of cognitive processes. It’s a 300 millisecond time frame that measures brain activity. This includes attention, working memory and dysfunction in neurologic and mental disorders. Ongoing research sees it as a potential genetic marker of mental disorders.“As you age this performance drops and the speed drops,” David explains.And then there’s voltage activity that’s happening in the brain. And if you can assess and measure what’s going on in your brain, you can do something about it.So, this is a really big thing. And I want you guys to think about this. Right now you might be saying, "I'm not a brain scientist, I'm just listening to this." But there's, how fast does the brain respond? And how strongly does the brain respond? Because those are different things. And the reason my brain does what it does, I would say is clearly nutrition and mitochondrial enhancement and supplements and all that kind of stuff.It's a fascinating time to be upgrading your brain! “So, 10 years from now, the happy path is that with the brain scan, the artificial intelligence will know you and know what you need to optimize your brain,” David says. “There won't be a question of, in the ideal world, it's not a question of your brain is slowing down. It will know you on day one and say, “This is what you need to do. As long as you stay with this program, you're going to have an optimized brain. It's not going to slow.” That's my 10-year future.”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 866Clean Up Your Mouth! Saliva, Gums & Kissing Bad Bacteria Goodbye – Trina Felber with Dave Asprey : 866
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Kratom for Energy & Pain Relief: https://superspeciosa.com, use code DAVE to get 20% off High-Performance Leadership: https://www.humanpotentialinstitute.com/coach-training/ Support Immune & Digestive Health: https://justthrivehealth.com, use code ASPREY to get 15% offSPECIAL OFFERS FOR BULLETPROOF RADIO #866 LISTENERSDental Detox Kit: davesdentalkit.comLED Teeth Whitener: naturalteethwhiteners.com/daveIN THIS EPISODE OF BULLETPROOF RADIO... you’re going to find out how your oral health and gut microbiome are connected.My guest today is Trina Felber, RN, BSN, MSN, CRNA, the creator and CEO of Primal Life Organics, an all-natural health product company that specializes in oral health and skin care.After more than 25 years as a registered nurse and nurse anesthetist, Trina turned her attention to the mouth microbiome and how it influences all your body systems--whether you know it or not.She focuses on oral health as the gateway to internal health, so discuss topics that could give you clues about your own biology:Saliva is the “lifeblood” of the mouth; Red light (and blue!) can improve gum tissue; andWhat you must stop doing when brushing your teeth and why it matters so much to your oral health.Your Saliva: “Saliva is a secretion no one's talking about,” Trina says. “And it's one of, if not the most important secretion in your body, because it does so many things, including nitric oxide production. If you have an imbalance in the microbiome inside your mouth and inside your gut, nitric oxide declines and your body can't produce nitric oxide. … Nitric oxide is a vasodilator, it's related to internal health, it's anti-inflammatory, it creates better sleep and better brain function.”Your Gums: “Red light therapy is going to help with the condition of your gums, it's going to improve the overall environment inside your mouth, and it's going to help with the right environment to grow the right bacteria that in the long-term is going to help with nitric oxide production,” Trina says. “Red light therapy actually penetrates your gum tissue and will increase blood flow and reduce inflammation of the gum tissue.”Your Brushing Habits: “Brushing too hard, we don't think about it, but it's common sense, but we still do it because you feel like you need to scrub to get your teeth clean and your gums,” Trina says. “But a lot of people just brush way too hard. It's really a soft motion. The softer you brush, the more you actually stimulate detoxification and increase blood flow. It's like a massage. Sometimes when you massage too hard, you create inflammation, you create more problems. And the softer that you massage, like lymphatic massages, are extremely, there's no depth to them. It's very light touch.” (Even with a sonic toothbrush!)Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ep 865Mimetic Desire Shatters the Myth of Why You Want – Luke Burgis with Dave Asprey : 865
EWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Find Out Your Biological Age: https://glycanage.com, use code DAVE to get 20% off testing packages Get Salty AF: https://drinklmnt.com/dave, from unflavored to classy combos like mango chili to the new watermelonControl Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentIN THIS EPISODE OF BULLETPROOF RADIO...Do you know why you make choices that are bad for you? Or why you end up with burnout, bad diets and other things that cause you harm, when you know you’d be better off choosing something else? This episode cuts through the noise, everything you’re sold and told to want, and helps you answer those very questions.Luke Burgis researched and studied the theory that underlies your tendency to follow other peoples’ wants, called mimetic desire. Explored by prominent French thinker René Girard, mimetic theory of desire says humans don’t want anything autonomously and independently. “Girard discovered that we come to desire certain things not through biological drives or pure reason, nor as the longing of our deepest, most authentic selves, but through imitation,” Luke says in his book, “Wanting: The Power of Mimetic Desire in Everyday Life.” Desire, as Girard used the word, does not mean the drive for food or sex or shelter or security. But after meeting those needs, we enter the domain of desire. And knowing what to want is much harder than knowing what to need.”In studying the work of Gerard, Luke realized that his goals and dreams were a product of other people’s expectations of him and he was actually following the desire of what he was seeing in others (that’s why he was miserable, burnt out, in poor physical health and felt horrible). “The truth is that desires are derivative, contagious, and therefore competitive, and that’s why they often lead to conflict,” Luke explains. “The lie is that I want things entirely on my own, uninfluenced by others. By rejecting the truth, I deny the consequences of my desires on other people, and theirs on me.”Luke and I dive into how to get past the innate desires of success and wealth that most of us are taught to value and really move into your own individual dreams and self-desires. “Mimetic desire exists on a spectrum,” he says. “And that there are some things that can't be explained medically at all. Something beautiful like a sunset, or like a beautiful woman that I'm attracted to. There are very clear scientific sort of physiological things going on there. So, let's make a distinction. Mimetic desire exists on a spectrum where those hardwired physiological things like thirst and hunger, those have been met, right? And we're sort of now in a more abstract world.”Armed with this knowledge, you can make better choices about who you trust and build self-awareness around your choices to empower your own life. You can find holistic models that work for you in all areas of your life (not just at your job), and why those models are important to find sooner rather than later.“The constant looking to what other people are doing or saying or wanting, or achieving, is just the fastest way to be miserable for one thing, but also the fastest way to miss opportunities, because we're just constantly looking to our right and our left rather than forward or up,” Luke says.Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.