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The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

1,548 episodesEN

Show overview

The Human Upgrade: Biohacking for Longevity & Performance has been publishing since 2011, and across the 15 years since has built a catalogue of 1,548 episodes, alongside 67 trailers or bonus episodes. That works out to over 1400 hours of audio in total. Releases follow a several-times-a-week cadence.

Episodes typically run thirty-five to sixty minutes — most land between 48 min and 1h 6m — and the run-time is fairly consistent across the catalogue. It is catalogued as a EN-language Health & Fitness show.

The show is actively publishing — the most recent episode landed yesterday, with 103 episodes already out so far this year. The busiest year was 2025, with 152 episodes published. Published by Dave Asprey.

Episodes
1,548
Running
2011–2026 · 15y
Median length
58 min
Cadence
Several per week

From the publisher

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

BONUS: The Anti-Aging Molecule Backed by Nobel Prize Research : 1492

Jun 28, 202612 min

Fish Oil Doesn’t Work? Anti-Aging Butterflies, the Ancient Brain Focus Switch, and the Best Brain Diet : 1491

Jun 26, 202613 min

The 'Secret Sauce' To A 10/10 Morning Routine : 1490

Jun 25, 202638 min

The Biohacking Secrets of Dubai | Dr. Elie Abirached : 1489

Jun 23, 202625 min

It's Weird, But It Turns On Your Body's Anti-Aging Switch Fast : 1487

Jun 21, 202615 min

Sugar-Free Backlash, Taurine Fail, Copper Brain Therapy, Childhood Biohacking, Strength Training : 1488

Jun 19, 202611 min

BDNF Superpowers Through MDMA and Ketamine | Dr. Dave Rabin : 1486

Jun 18, 20261h 1m

The Skin Mistakes That Age You Fast and Kill You Slow | Dr. Michael Christopher : 1485

Jun 16, 202644 min

Just 1 Gram Activates Your Deep Focus Switch (Take THIS) : 1484

Jun 14, 202611 min

World Cup, Sunscreen, Hair Regrowth, Caffeine Chewing Gum, and more... : 1483

Jun 12, 202611 min

Brain Fog, Memory Loss, and Alzheimer's Prevention | Dr. Majid Fotuhi : 1482

Jun 11, 20261h 19m

The Foods That Starve Cancer | William Li : 1481

Jun 9, 20261h 3m

I Drink Fat To Look Shredded (Lost 100lbs) : 1480

Jun 7, 20267 min

Putin Longevity, Pancreatic Cancer Cure, AI Therapy, GLP-1 Breast Cancer... : 1479

Jun 5, 202610 min

How to Get Microplastics Out of Your Body | Mara Labs : 1478

Jun 4, 20261h 1m

Peptide Power Without Needles: Smarter Dosing for Longevity | Justin Kirkland : 1477

Jun 2, 202654 min

Brain Fog Starts in Your Feet (Scientifically Proven) : 1476

May 31, 20268 min

NASCAR Death, Steroid Olympics, Genetic Age Truth, and Gut Depression... : 1475

May 29, 20268 min

Combine Creatine With THIS To Fight The Root Cause of Aging | Andrew Salzman : 1474

May 28, 20261h 23m

The Doctor With Answers To Your Mystery Symptoms | Jessica Peatross : 1473

May 26, 20261h 16m
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