The Human Upgrade: Biohacking for Longevity & Performance

IN THIS EPISODE OF THE HUMAN UPGRADE™... Dave talks with Mandy Pennington, a longtime Upgrade Collective member and dedicated hacker who has used biohacking techniques successfully to upgrade her body and mind.Mandy is a sharp and curious person who wants to learn more about how to apply the topics in Smarter Not Harder to her spirituality, quantum energy, spirit guides, and leading a purpose-driven life that feels right for her soul.An important aspect of this episode is focussed on how Mandy can refine her current spirituality practices, and increase her spiritual resilience to align with the next steps on her biohacking journey. Which is something that will likely resonate with you. Watch this episode on YouTube!Note: The “Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / AmazonKnowing Labs: Test Your Own Biology: https://knowinglabs.com/dave, use code dave to save 20% off any test kitCapture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™... I am honored and grateful to bring you a conversation that I recorded in person with Gurudev Sri Sri Ravi Shankar at the Art of Living Center in Los Angeles. Gurudev Sri Sri Ravi Shankar is a leader of an international movement with more than 50 million followers who do breathwork every single morning. He has worked for 40 years as a global ambassador for peace at the highest levels. I did his breathwork exercises every morning without fail for five years while fixing my mind, body and nervous system, and I have a huge amount of respect for his work in the world. It was a joy to chat with him in person and his childlike curiosity, enthusiasm for teaching, and deep understanding of the world are echoed in every word of this episode. Gurudev is a true visionary, so I am grateful that he set aside time to talk with me so I could share his wisdom with you. Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Solutions for High Performance: https://sleepbreakthrough.com/dave, use code DAVE10 to get an extra 10% offComfort Options for Hot & Cold Sleepers: https://sleep.me/daveasprey, use code ASPREY for 25% off your purchaseDave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / AmazonSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™...I do something different. Over the past 1000+ episodes, I have spent a lot of time talking and learning from my guests, but I have heard over and over that you would like to hear more from me about what I am doing, trying and thinking. Well, that can be awkward to do sitting alone in front of a microphone. A while ago, Danica Patrick interviewed me and it is one of my favorite podcast interviews ever. Danica did a great job of digging into why I do what I do, why I think the way I think, and best of all she allowed me to talk about parts of my life that I have never talked about anywhere else. So, Danica has kindly allowed me to drop that episode from her podcast, Pretty Intense, right here on the Human Upgrade.You are going to learn a lot from the episode. We hit on a lot of pretty next-level stuff - our conversation even allowed me to dig into the concept of old souls (or reincarnation), and how that affects our current life.Danica is a fascinating person and an excellent interviewer. You are going to enjoy this feed drop. Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Kickstart Autophagy: https://timelinenutrition.com/DAVE, use the code ASPREY10 to get 10% off any planNature’s Nootropic: https://trukava.com, use code DAVE15 to get 15% offDave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / AmazonSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

H.V.M.N. sponsored this episode.IN THIS “UPGRADE SPOTLIGHT” EPISODE OF THE HUMAN UPGRADE™…Metabolic biochemist Latt Mansor, Ph.D., joins the show from H.V.M.N. (Health Via Modern Nutrition), where he leads research for the company. He’s an expert in metabolism who consults with elite sport, military, clinical and research organizations. As a key biomarker of metabolic health, ketones are a source of fuel for your brain and body. They’re different from glucose and fat—and more efficient. Learning about the different kinds of ketones and how they work can help you both understand and harness their power. This discussion explains exogenous ketones, BDO-specific ketones BHB and ketone esters. You’ll also find out how to measure your ketones and why it’s important.Ketones have been shown to be anti-inflammatory. Another benefit happens during exercise. The increase in your ketone levels directly increases BDNF (brain-derived nootropic factor). When you raise ketones, you have a more flexible brain.Latt gets into the research behind H.V.M.N.’s development of drinkable ketones to improve performance. Ketone-IQ™ give you advantages like:Mental clarity and cognitive benefitsOxygen efficiencySustained energyPerformance, endurance and recoveryWeight management and improved metabolic healthSPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://hvmn.com/DAVE, use code Dave to get 20% off.Watch this episode on YouTube!NEW IN 2023!Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / Amazon9th Annual Biohacking Conference: Come join like-minded people for three days of awesome biohacking, learning and connecting! June 22-24, 2023, in Orlando, Florida. https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… Dr. Kelly Brogan shares why her views often go against conventional thinking—on topics from pharmaceuticals to sex to pole dancing to relationship compatibility. She's a psychiatrist who specializes in psychosomatic medicine and integrative holistic medicine. Her root-cause resolution approach to psychiatric syndromes and symptoms coupled with other support techniques helps women reclaim their divine feminine power.I previously talked with Dr. Kelly on episode #635 about her book, "Own Your Self: The Surprising Path Beyond Depression, Anxiety, and Fatigue to Reclaiming Your Authenticity, Vitality, and Freedom.” This romp of a discussion tackles women’s power and what it means to claim or reclaim it. And how women themselves can be harmful critics of other women’s choices. Dr. Kelly went through profound personal changes over the past few years that led to changes in her business, too. Changes that rattled some people and brought out the worst kind of social media attention. She talks about how she’s stayed firmly in her choices and offers tips for you to do the same. She also gets into why the differences in feminine and masculine power matter now more than ever. It starts with your relationship with yourself.This fun, informative interview gets a little wild and shares profound insights you can apply to your next life move.Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! A Probiotic to Ease Stress: https://www.omnibioticlife.com/DAVE, use code DAVE20 to get 20% offCustomized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave, use code DAVE10 to get 10% offDave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. IndieBound / Barnes & Noble / Apple Books / Amazon9th Annual Biohacking Conference: https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™…you’re going to learn how to work with your own biology, adapt to adversity, and get resilient AF. Doctor, educator and entrepreneur Dr. Molly Maloof joins the show in person in Austin, Texas, to talk about her debut book, “The Spark Factor: The Secret to Supercharging Energy, Becoming Resilient, and Feeling Better Than Ever.” For women biohackers, it’s all about energy—and hormones. “Cycles are exactly why the way guys biohack doesn’t always work for us [women]; we have hormonal and physiological differences, and importantly, different biological imperatives, from an evolutionary standpoint,” she says in her new book.She last appeared on episode #706 and talked about how blood sugar powers your energy. This time, she explains why mitochondrial dysfunction is at the root of the collective human energy crisis and what you can do about it. Dr. Molly says four culprits reduce your energy capacity: inactivity, overeating and poor nutrition, too much stress and social disconnection."Spark Factor" outlines clear and actionable steps for women on how to make, charge, use, tune, and plug in your own batteries. New to biohacking? Start where you are. More advanced biohacker? You’ll learn tips and tweaks to get you to another level. Molly offers low-tech and tech-free guidance, too. It’s up to you where to start and how far you want to take it.Her unique view of human performance incorporates technology and psychedelics. In this broad conversation, she covers sex and relationships, too.Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Support Your Neck & Fight Aging: www.envypillow.com and use DAVE15 to get 15% off any pillowDave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / Amazon9th Annual Biohacking Conference: https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… board-certified OB/GYN and “menopause warrior” Mary Claire Haver, M.D., joins the show to give women a toolkit to manage what comes before, during and after menopause.She explains the science of women’s hormones, physiology and brain during the menopausal transition.She breaks down the studies, risks, and age timing of Hormone Replacement Therapy.She gives you information you can use to both help yourself and ask for help from medical professionals.She arms you with actions that work based on what is happening to your biology and brain chemistry during the years leading up to and after menopause.“When I talk about the menopausal toolkit, HRT is just one small part of what I counsel patients about,” Dr. Haver says. “We talk about nutrition, we talk about exercise, we talk about stress reduction, we talk about sleep, we talk about possible other pharmaceuticals. And of course, we talk about supplementation. It's like a tackle box and everything is important.”Although Dr. Haver’s career included taking care of women at all life stages, she didn’t expect to experience the shocks of her own menopause. So, she went looking for answers and took action along the way. She changed the entire focus of her medical practice to menopause. She also channeled the power of social media to provide menopause education and reaches more than 2 million on her TikTok channel alone.Her new book, “The Galveston Diet: The Doctor-Developed, Patient-Proven Plan to Burn Fat and Tame Your Hormonal Symptoms," lays out three specific action areas: intermittent fasting, anti-inflammatory nutrition, and fuel refocus.Menopause is having a moment. (As Lizzo would say, “It’s About Damn Time.”) From investor-backed start-ups in a $6B market to celebrity-led wellness brands to demands for more science—women, and women medical professionals, are changing mid-life menopause dynamics.Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Liquid Ketones for Better Energy, Focus and Endurance. https://hvmn.com, use code DAVE to get 20% offDave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. Pre-order yours today: IndieBound / Barnes & Noble / Apple Books / Amazon9th Annual Biohacking Conference: https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™…Susanna Soeberg, Ph.D., a Danish researcher, international scientist and expert in cold and heat therapy for health and performance, explains how you can harness the massive benefits of cold water immersion (winter swimming), sauna, breathing, and your metabolism.When it comes to biohacking, a few things rise to the top and make a pretty big difference in your body and brain. Through her research, Susanna discovered the minimum threshold of cold and heat exposure for health benefits. We get right into that on the show. She also works with functional breathing during cold environmental conditions and cold water immersion, especially winter swimming. Have you been considering this biohack for awhile? Baby steps won’t get you there—prepare to go all-in with the cold. “You could take cold showers, for sure,” Susanna says, “but it's not going to activate your parasympathetic nervous system in the same way as submerging yourself into cold water.”Earning a Ph.D. in metabolism at the University of Copenhagen set her on course to focus her expertise on ways metabolism works for and against you—and what you can do to improve your metabolic profile. She researches obesity, Type 2 diabetes and insulin management, as well as how brown and white adipose tissue (fat) function differently within the human body.In Susanna’s new book, “Winter Swimming: The Nordic Way Towards a Healthier and Happier Life,” she describes the benefits of winter swimming and cold water immersion on your physiology, mental health, and capacity for resilience.Watch this episode on YouTube!SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.soeberginstitute.com and use code DAVE for a special discount on Susanna Soeberg’s 3-week course, The Thermalist CureTM.Opportunity: Breath, Cold, Stress & Resilience Conference, Feb. 18, 2023. Presentations by Susanna Soeberg, James Nestor and other experts. Register here.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Capture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount9th Annual Biohacking Conference: https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Leela Quantum Tech sponsored this episode.IN THIS EPISODE OF THE HUMAN UPGRADE™…you’ll learn why energy frequencies have such a powerful influence on human physiology. Skeptics take note: science backs this up.Philipp Samor Von Holtzendorff-Fehling introduced quantum energy on episode #809 and its benefits on body function, cellular voltage and chakra energy. He returns to the show with exciting new research that further validates the power of this energy and its frequencies on human physiology.“Energy and frequency—that’s where the real truth is.” Philipp says. “And that's where the real life also is.”Leela Quantum Tech creates blocs (Infinity, Quantum, Travel), frequency cards, H.E.A.L. capsules, and other products charged with quantum energy. The products have been through single- and double-blind, randomized studies and tests. This research has measured mental and physical energy, organ function, neutralization of radioactive particles, protection against pesticides and herbicides, and much more. Studies also explored how quantum energy affects ATP production, HRV (heart rate variability) and food allergies. You can feel and measure the effects. And dark field microscopy studies (placebo-controlled and double-blind) performed by Dr. Beverly Rubik in the U.S. and the BESA institute in Austria looked at the physical effectiveness of Leela Bloc technology.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://leelaq.com and use code DAVE10 to get 10% off.Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Protein Bars with All the Good Stuff and None of the Crap: https://rowdybars.com, use code DAVE to get 10% off9th Annual Biohacking Conference: https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™…Harvard psychiatrist, researcher and assistant professor Christopher Palmer, M.D., introduces a bold new premise about the root cause of mental illness based on decades of research.Dr. Palmer integrated existing theories and research into one unifying theory—the brain energy theory of mental illness that’s rooted in your metabolism. Through his research, he initially pioneered using a medical ketogenic diet to treat psychiatric disorders. In this conversation, you’ll learn how he went even further to uncover the connection between mental health and metabolic disorders of the brain. That connection lies in mitochondrial dysfunction or dysregulation.His new book, “Brain Energy: A Revolutionary Breakthrough in Understanding Mental Health and Improving Treatment for Anxiety, Depression, OCD, PTSD, and More,” also explains the increased risk for mental disorders in all metabolic conditions, including diabetes, heart attacks, strokes, pain disorders, obesity, Alzheimer’s disease, and epilepsy. “Once you see the big picture of metabolism and all of the things that influence metabolism, you actually can see novel ways to intervene,” Dr. Palmer says. “And you can also raise some red flags about some of our current treatments.” Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Mineral-rich Salt—Unrefined & Unprocessed: https://oryxdesertsalt.com, use code DAVE10 to get 10% offSleep Solutions for High Performance: https://sleepbreakthrough.com/dave, use code DAVE10 to get an extra 10% off9th Annual Biohacking Conference: https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™…you’ll meet Gloria Mark, Ph.D., who studies how digital media impacts people's lives. Her research specifically covers how attention is affected by, and has changed, with the rise of the digital age. She’s found that attention span now averages 47 seconds on a screen—and even that’s shrinking.As a Chancellor’s Professor of Informatics at the University of California-Irvine researching human-computer interaction, Gloria examines how people handle multitasking, task-switching, interruptions, and emotions. Her new book “Attention Span: A Groundbreaking Way to Restore Balance, Happiness and Productivity” looks at human technology use from a psychological perspective.“In the thousands of hours that I have studied people in the course of their daily work, I have heard a common sentiment,” Gloria says in her book. “People report that they are overworked and exhausted because they have to deal with too much information and too many messages.”This conversation gets into the science of attention, the stress it’s causing, plus real solutions for how you can regain focus with your personal technologies. You’ll learn:How to recognize the four main types of attention;What consequences of constant interruption do to your stress levels and productivity;How to achieve focus, rhythm and balance in a day filled with attention-switching; How to structure a flow state within your day; and What four things you can do to gain agency in the digital world.  Watch this episode on YouTube!Shield Yourself from EMFs: https://quantumupgrade.io, use code DAVE to get a two-week free trialKnowing Labs: Test Your Own Biology: https://knowinglabs.com/dave, use code dave to save 20% off any test kit9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll meet Robert Waldinger, M.D., who leads an extraordinary scientific study on happiness that’s still going strong after eight decades. The study set out to understand human health by what made people thrive.Since 1938, the Harvard Study of Adult Development has tracked two groups of men and their families with the goal of discovering what really makes for a good life. Along the way, thousands of questions were asked, and hundreds of measurements were taken—from brain scans to blood work. Three strong themes emerged from the study: Social connections are really good for you. Loneliness kills.It’s the quality of your close relationships that matters.Good close relationships don’t just protect your body, they protect your brain.Dr. Waldinger combined those lifelong case studies with modern psychological research in his new book, co-authored with Marc Schulz, Ph.D., “The Good Life: Lessons from the World's Longest Scientific Study of Happiness." This discussion gives you real-life tools to hack your happiness. You’ll learn things like:how relationships improve your physical, mental and emotional health. (More than you know!)how to evaluate the effect of your relationships on your well-being. (Don’t be dragged down.)what social fitness is and how to practice it. (Yes, it’s a flex.)ways to enliven and energize your relationships. (Energy totally matters.)why casual and work relationships matter more than you think. (A surprisingly big contribution.)Watch this episode on YouTube!Don’t Miss This! Dr. Waldinger’s TEDtalk about the study is one of TED’s Top 10 episodes and viewed more than 43 million times.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Energize Your Brain & Body: https://nootopia.com/davegenius, use code DAVE10 to get an extra 10% offClear Out Zombie Cells with Senolytics: https://neurohacker.com/dave, code ASPREY to get an additional 15% off9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life.https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Neurohacker Collective sponsored this episode.IN THIS "UPGRADE SPOTLIGHT" EPISODE OF THE HUMAN UPGRADE™… you’re going to learn about the zombie cells taking up valuable space in your body and how you can clear them out with senolytics.When these zombie cells accumulate (formally called senescent cells), they negatively impact how you age. You may experience symptoms like joint discomfort, low mental and physical energy, poor metabolic health, and diminished muscular response when you work out.Naturopathic physician Greg Kelly joins the show from Neurohacker Collective, where he’s director of Product Development. His expertise includes nootropics, anti-aging and regenerative medicine, weight management, sleep, and the chronobiology of performance and health.The hallmarks of aging include nine characteristics that organisms all the way up to humans share as we age, Dr. Kelly explains. One of those characteristics is senescent cells.This discussion gets into the reasons why senescence happens, the science of senolytics, exciting new research, and new product developments that help bodies naturally eliminate senescent cells. This means a better aging process for you!SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://neurohacker.com/dave and code ASPREY to get an additional 15% off. You can trial Qualia Senolytic for up to 100 days with a full 100% money-back guarantee. Watch this episode on YouTube!9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™... the new year starts off with a Legacy Upgrade conversation between Dave Asprey and Dr. Andrew Weil recorded live at True Food Kitchen in Phoenix, Arizona. Dr. Weil’s an internationally known pioneer and leader in integrative medicine. He’s also a Harvard-trained botanist and medical doctor recognized worldwide for his views on living a healthy lifestyle, his philosophy of healthy aging, and his critique of the future of medicine and health care. This broad discussion both hits the high points and goes deep into nutrition, aging, energy, lifestyle, and, of course, tea. Specifically, vibrant green matcha. (Or as Dave says, “It looks like green paint.”) There’s a lot of knowledge and humor shared, as well as hard-hitting truths: “One of the most toxic cultural messages here is that the value of life diminishes with aging,” Dr. Weil says.His five pillars of good health touch on foundational elements that contribute to your core vitality and life force. Eat right! Learn the principles of nutrition and apply them to your lifeGet regular physical activityLearn and practice methods to neutralize the harmful effects of stressMaintain emotional and intellectual connectivity as you go through lifeAttend to your spiritual well-beingMore about Dr. Andrew Weil: He founded the Andrew Weil Center for Integrative Medicine at the University of Arizona. He champions the use of medicinal plants and alternative medicine, as well as the reform of medical education. He’s a clinical professor of medicine and a professor of Public Health at the University of Arizona and the author of more than a dozen books on health, wellness and optimal living. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to www.matcha.com and use code Bulletproof15 to save 15% off sitewide.Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!A Probiotic to Ease Stress: https://www.omnibioticlife.com/DAVE, use code DAVE20 to get 20% off. 9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… Humble The Poet joins the show to talk about a unique perspective on love. You’ll learn:what “real” love means (hint: it’s not found or earned) and how to recognize it in your life. how to shift away from a mindset of earning more, achieving more, and gaining more attention so you can clear pathways for love to enter and flourish in your lifehow to ditch restrictive “resolutions” (that fail more often than they succeed) and instead set intentions that allow you more freedom to love yourself and others.This Canadian-born rapper, spoken-word artist, poet and international bestselling author began reciting spoken word poetry in coffee shops more than a decade ago. That creative outlet turned into an adventure that crossed genres, mediums and oceans. His style stimulates audiences with ideas that challenge conventional wisdom. His first two books, “Unlearn” & “Things Nobody Can Teach Us” became international bestsellers. His newest book focuses on self love, love for others, defining love in a different way, and how to ease up on expectations that may be holding you back: “How to Be Love(d): Simple Truths for Going Easier on Yourself, Embracing Imperfection & Loving Your Way to a Better Life.” “I’m writing this because I’m desperate,” he says in the book. “Desperate to realize love, accept love, and learn how I keep f**king it up.”Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Comfort Options for Hot & Cold Sleepers: https://sleep.me/daveasprey, use code ASPREY for 25% off your purchaseMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount.  Kickstart Autophagy: https://timelinenutrition.com/DAVE, use the code ASPREY10 to get 10% off any planSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™…… Ari Whitten, Ph.D. (Cand.), CES, PES, explains how to double your energy through improved resilience, cell defense, nutrition and supplementation.  In his newest book, “EAT FOR ENERGY: How to Beat Fatigue, Supercharge Your Mitochondria, and Unlock All-Day Energy,” Ari explains that 5.4 million adults in the U.S. have been diagnosed with chronic fatigue syndrome (the most severe case of fatigue). However, the true fatigue epidemic affects 50 to 100 times more people with many experiencing some level of being flat-out tired as hell.This conversation gets right into the role of mitochondria in human energy. The cause of fatigue is mitochondrial dysfunction, Ari says. The biggest factors that affect your mitochondria include:Circadian rhythm dysregulation and poor sleep Carrying too much body fat and too little muscle mass Poor gut and microbiome health Blood sugar dysregulation Nutritional toxicities and deficiencies Neurotransmitter and hormone imbalances Ari recommends science-backed ways that you can get your mitochondria moving, dial in your nutrition and upgrade your brain, gut and hormones. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Mattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProA Cleaner Nicotine Alternative: https://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozenges9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™…… Steven Gundry, M.D., explains that ketones aren’t the fat-burning molecules you think they are. Ketones actually work to enhance health, weight loss, and longevity by acting as signaling molecules that stimulate your mitochondria. A cellular process known as “mitochondrial uncoupling” happens. He debunks common myths about keto in his newest book, “Unlocking the Keto Code: The Revolutionary New Science of Keto That Offers More Benefits Without Deprivation,” and shares eight “keys” that unlock the keto code: Intermittent fasting or time-controlled eating PolyphenolsDietary fiber Fermented foods PolyaminesCold temperaturesHot temperaturesRed light therapyUpgrading your nutrition with keto gets even simpler in this conversation that gives you real food examples of how to ignite your mitochondrial uncoupling process without a monotonous, limiting, high-fat diet.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Get 30% off products at https://gundrymd.com. Use code DAVE30 at checkout.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Clean up Zombie Cells with Senolytics: https://neurohacker.com/dave, use code Asprey15 to save 15%Cooler Temps for Deeper Sleep: https://www.chilisleep.com/, use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep System. Learn more: Upgrade Spotlight: Improve Your Sleep With a Cooler Body Temp – ChiliSleep – #923Business Growth With SEO: https://www.stephanspencer.com, get a FREE consultationSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… natural vision expert Claudia Muehlenweg explains how you can take better care of your eyes and improve your vision. Her work is based in the Bates Method. She focuses on finding the root cause of blurry vision instead of using symptomatic treatments like glasses, contacts or surgery that actually can make eyesight worse in the long term.For nearly 15 years, Claudia’s taught eyesight improvement for presbyopia, myopia, astigmatism, hyperopia, strabismus, convergence insufficiency, and eye diseases such as cataracts, macular degeneration and glaucoma. She also helps people restore clarity after corrective surgeries like LASIK have worn off. Claudia starts with root causes in your body, including nervous system regulation. She then brings in bodywork, breathwork, rest, light and movement healing methods. Listen on to get practical solutions and essential Dos and Don’ts for good eyesight.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!A Pre-Alcohol Probiotic to Offset a Rough Morning After: https://zbiotics.com/dave, use code DAVE to save 15% off your first order. Learn more: The Bacteria That Lets You Drink Alcohol Again – Zack Abbott, Ph.D. – #1000Biostack for High Performance: https://vatellia.com, use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale BusterSleep Better on Natural Memory Foam: https://myessentia.com/daveasprey, use code DAVE to get an extra $100 off an Essentia mattress purchase on top of Essentia’s Holiday 25% off sale. Through Dec. 31, 2022, only. Learn more: Mattress Smarts 101 for High-Performance Sleep – Jack Dell’Accio – #875See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this Episode of The Human Upgrade™… Dave talks with Rachelle Copeland about putting her energy into healing facial injuries and building new tissues—starting with the central nervous system. Rachelle experienced an accident that injured her face, teeth, nerves and jaw. She wants to heal quickly and avoid scarring and long-term damage while also managing the accompanying emotional trauma.This intervention looks at ways to heal and recover both internally and externally, covering suggestions such as: EMDR, Tapping, EFT for physical and emotional trauma (What Is EMDR and How Does It Work?, Nick Ortner: The Tapping Solution for Pain Relief – #219, Tap into Tapping: The EFT Episode – Dawson Church # 474)Jaw misalignment (Dr. Dwight Jennings: TMJ, Jaw Pain, & Substance P – #179)Vagal nerve (Stephen Porges: The Polyvagal Theory & The Vagal Nerve – #264, The Nervous System Circuitry of Safety, Sound & Gratitude – Stephen Porges #573)Hyperbaric therapyCraniosacral workInflammationOral and topical cayenneRed and infrared, LED or laser light therapy Ozone therapySupplements to support healingEnzymesIf you’re recovering from injury, take a listen to this episode for tips and resources on how to heal.Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Vascular System Protection https://calroy.com/dave, save on a 3-pack to protect your blood vessels from vulnerable plaqueGet Fit in Five Minutes: https://www.carolbike.com, use code HumanUpgrade to get 2 years of free membership (a total savings of $360) on the CAROL Bike 2.0 and a 100-day home trial. 9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life.https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Viome sponsored this episode.IN THIS EPISODE OF THE HUMAN UPGRADE™… entrepreneur and philanthropist Naveen Jain joins the show in person at the Beverly Hilton to talk about new developments in the human biome—particularly the oral microbiome. Turns out, there may be more density in your gut microbiome, but there’s more diversity in your oral microbiome.Naveen’s company, Viome, built an AI-driven platform that analyzes the interaction between food, your body’s biomes, and your cells from at-home tests. Your results are used to develop precise ways of eating and taking supplements that prevent and can even help reverse chronic disease. They’ve so far collected 425,000 samples showing 600 trillion data points.The newest Viome test kit takes a look at your oral health. Viome prepares custom supplements, probiotics and prebiotics with the exact ingredients in the exact dosages you need based on your personal test results. This customization is important because supplements are not universally healthy, more isn’t better, and consuming nutrients and biotics you don’t need can actually do more harm than good. Custom formulations work with and for your own physiology.Viome testing also helps you see your personal health trends over time. Your tests could show different results at six months or a year. Then, your supplements would be adjusted to your changing physiology. Check out Viome’s at-home test kits:Oral Health Intelligence: coming soon!Full Body Intelligence (gut, cellular, oral health)Health Intelligence (gut, cellular health)Gut Intelligence (gut health)Cancer Detect (oral & throat)SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://viome.com/dave and use code DAVE10 to get 10% off tests and 10% off a 12-month subscriptionWatch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Nature’s Nootropic: https://trukava.com, use code DAVE15 to get 15% offUpgrade Your Air Quality: https://hypoair.com/Dave/Mattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Pendulum sponsored this episode.IN THIS EPISODE OF THE HUMAN UPGRADE™…molecular biologist and biochemist Colleen Cutcliffe, Ph.D., returns to the show with brand new science about your gut. She’s a regular guest because she and her team at Pendulum continue to uncover innovative ways to improve your gut health, your metabolism, your immune system, how your brain works and how long you live. This time, Akkermansia’s back in the spotlight, with more than 300 new studies showing connections to weight, metabolism and immunity. A unique and novel probiotic strain (species of bacteria) naturally found in your gastrointestinal tract, Akkermansia muciniphila, directly interacts with your gut lining and helps regulate the mucus lining in your gut. Now, there’s growing evidence showing Akkermansia to be a keystone bacterial strain.This conversation dives into the latest research and what it means for you. You’ll learn how to apply this new knowledge and how to boost Akkermansia in your gut.SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://pendulumlife.com and use promo code DAVEVIP to get 20% off your first month of membership.                                                                                                      Watch this episode on YouTube!A Pre-Alcohol Probiotic to Offset a Rough Morning After: https://zbiotics.com/dave, use code DAVE to save 15% off your first order. Sleep Better on Natural Memory Foam: https://myessentia.com/daveasprey, use code DAVE to get an extra $100 off an Essentia mattress purchase on top of Essentia’s Holiday 25% off sale. Through Dec. 31, 2022, only. Go Deep on Relaxation & Sleep: https://balooliving.com/dave, use code DAVE for a special discount. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll find out that kids are killing themselves more often and at younger ages. Suicide prevention expert Dr. Mark Goulston joins the show to discuss the very real and very urgent topics of youth mental health and suicide—from pre-teens to teens to young adults. These issues concern everyone, not only families, educators or professionals who connect with young people. Here’s why:Suicide shows up in the top three causes of death in young people between the ages of 10-24, according to 2020 stats from the Centers for Disease Control and Prevention (CDC) WISQARS Leading Causes of Death Reports.Young people are hurting. The National Alliance on Mental Illness reports that nearly 20% of high school students say they’ve had serious thoughts of suicide and 9% have made an attempt to take their lives. Dr. Mark explains that many young people struggling mentally and emotionally feel like they're a burden to everyone. And they don’t have confidence that parents can help them feel better. You’ll learn a lot during this conversation, such as:factors driving teen mental health issues and teen suicide.what’s going on in the teen brain from a developmental perspective that leads them to think that death is a preferable alternative to working through life situations.signs or red flags that a teen is struggling. how parents and adults often can diminish or dismiss teens’ emotions, situations with friends or love relationships.what emotional intelligence skills are most useful for parents/adults to better understand teens.how to talk to teens—whether you’re a parent or a caring adult in a teen’s life.how to improve listening in a culture dominated by tech.how to listen to teens and help them realize and understand their emotions—without cutting them off, interrupting them, or jumping to advice and solutions.when to seek professional intervention.More about Dr. Mark Goulston: He's a retired psychiatrist, former UCLA professor of psychiatry and former FBI and police hostage negotiation trainer. He recently received the “Shine the Light Media Award” from the Los Angeles County Medical Association for bringing attention to teen mental health and suicide. He’s the author or co-author of nine books: “Just Listen: Discover the Secret to Getting Through to Absolutely Anyone,” ranks in the 15 Best Communication Skills Books of All Time.Watch this episode on YouTube!Biostack for High Performance: https://vatellia.com, use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale BusterGet Fit in Five Minutes: https://www.carolbike.com, use code HumanUpgrade to get 2 years of free membership (a total savings of $360) on the CAROL Bike 2.0 and a 100-day home trial.Business Growth With SEO: https://www.stephanspencer.com, get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn about a new holistic framework for self-healing and how to heal yourself with prompts, tools and actionable tips.Using the tenants of holistic psychology, Nicole LePera, Ph.D., created a different way to reach people and equip them with the tools necessary to heal themselves. Holistic psychology focuses on the mind, body, and soul in the service of rebalancing the body and nervous system and healing unresolved emotional wounds.  It’s all about a daily practice of creating your own wellness by:seeing yourself from a new perspective,breaking negative patterns, healing from your past, andcreating your conscious self.Nicole, the author of the New York Times Bestselling Book “How to Do the Work: Recognize Your Patterns, Heal from Your Past, and Create Your Self,” builds on that theme and goes even deeper with her newly published “How to Meet Your Self: The Workbook for Self-Discovery” workbook.In this conversation, you’ll find out how to:objectively and compassionately observe the physical, mental, and emotional patterns that keep you stuck.deep dive into your ego, trauma and emotions so you can safely do the inner work that can transform your outer world.change ingrained beliefs and habits so you can move toward realizing your authentic self. Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! A Cleaner Nicotine Alternative: https://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozengesMattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProTest Your Own Biology: https://knowinglabs.com/dave, use code dave to save 20% off any test kitSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… Dan Buettner joins the show to talk about the origins and food foundations of Blue Zones. He discusses how they were discovered, what makes them different, and what’s changed for people living there over the past few decades. And the big question—is it still possible to live to 100?Dan, an explorer, National Geographic Fellow, award-winning journalist and producer, and photographer, has studied and written extensively about the five places in the world—dubbed Blue Zones—where people live the longest, healthiest, and often happiest lives. He’s partnered with epidemiologists, anthropologists, medical researchers, demographers, and statisticians to take a data-based approach to everything from genetics to census data.Combining this intensive research with cultural immersion, Dan’s brought out aspects of Blue Zones lifestyles—like food and social connection—that form a foundation for human life quality and longevity. He’s the bestselling author of a series of Blue Zone books.In Dan’s latest Blue Zones adventure, he took a road trip across the United States to explore food and communities. He found that pockets of Blue Zones do exist throughout the U.S. He talked to heritage cooks passing on recipes to younger generations. He uncovered the traditional roots of plant-forward cuisine in the United States and presents both traditional and revolutionary ideas in vegetarian food in his newest book, “The Blue Zones American Kitchen: 100 Recipes to Live to 100.” Stunning photography and recipes show the vitality of both food and people from five distinct areas: Indigenous, Native & Early American, African American, Latin American, Asian American and Regional and Contemporary American.Dan also dug deep into the country’s food history and brings to light the dramatic changes in food processing, regulation, government intervention, and leadership choices that have influenced food supply. He combed through 60 oral histories, scientific reports and academic papers to reconstruct traditional American diets. In “The Blue Zones American Kitchen,” you’ll find out why the 1970s were the worst decade for America’s food environment. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Upgrade Your Air Quality: https://hypoair.com/Dave/Nature’s Nootropic: https://trukava.com, use code DAVE15 to get 15% offMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount. Learn more: Magnesium: The Master Mineral That Conquers Stress – BiOptimizers – #669See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

(ZBiotics sponsored this episode.)IN THIS EPISODE OF THE HUMAN UPGRADE™… you'll find out how to counter the sometimes rough morning after you have alcohol. The key is a new genetically engineered pre-alcohol probiotic drink. Great timing as you head into the holiday season of celebrations.Zack Abbott, CEO & co-founder of ZBiotics, joins this 1,000th episode of the podcast to talk about new discoveries in alcohol metabolism, genetic engineering and GMOs (used in a good way!), and the power of microbes.Ever wondered why you feel like crap the morning after drinking alcohol? The cause is a byproduct called acetaldehyde that forms in your gut when you drink alcohol. The ZBiotics Pre-Alcohol Probiotic Drink breaks down acetaldehyde while you drink so you can feel better the morning after.Prior to starting ZBiotics, Zack, who has a Ph.D. in microbiology and immunology, worked in clinical trial design, researched HIV vaccines, and pursued novel antibiotics in both academia and industry.He invented the ZBiotics proprietary technology using genetic engineering to develop new probiotics—ones with specific, unique abilities to improve your daily life. He’s proving through science that incredible things can be done with GMOs and genetically engineered microbes.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://zbiotics.com/dave and use code "dave" to save 15%.Watch this episode on YouTube! Biostack for High Performance: https://vatellia.com, use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale BusterHarness Cold to Improve Health & Performance: https://www.cryobuilt.comBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this Episode of The Human Upgrade™...​Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.Sperm that swim together increase their chances of fertilizationLate-night eating is worse than you thoughtMetabolic markers can be measured through your sweatEye movements during REM sleep could delete unwanted memoriesEPISODE SPONSOR: Humic & fulvic minerals provide critical cellular support. Go to https://www.beamminerals.com and use code DAVE20 to get 20% off. Learn more: How Minerals Combat Glyphosate’s Harm – Caroline Alan – #948.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Timeline Nutrition sponsored this podcast.IN THIS EPISODE OF THE HUMAN UPGRADE™… immunologist Anurag Singh, M.D., Ph.D., MBA, Chief Medical Officer at Amazentis, joins the show to talk about urolithin A’s connection between inflammation, aging and your mitochondria. Urolithin A activates mitophagy and renews your mitochondria.  “It takes all the cellular garbage that has been accumulating over the aging process,” Dr. Singh explains. “It revs it up, so it recharges. And so now, you're cleaning your metabolic waste products much more efficiently and they become the building blocks. This is mitochondrial biogenesis, and that means newer, healthy mitochondria coming in.”This new conversation takes an exciting turn into immunity and your immune system’s two lines of defense: innate and adaptive. You’ll learn:how inflammation plus aging (AKA inflammaging) contributes to a weakened immune system and a growing incidence of cancer as you age;how inflammaging and cancer are connected to mitochondrial dysfunction specifically during the aging process; andhow to approach your immune health differently with this new knowledge.A new study recently published in Immunity looks at how immune cells fight cancer better with a focus on immune modulation, immune cell exhaustion and immune responses. “A lot of urolithin A is anti-inflammatory, but a lot of it is immune modulation," Dr. Singh says. "So, it takes a rewiring of the immune system and makes it more conducive to stopping harmful immune responses.”Watch this episode on YouTube!SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: To learn more about the benefits of urolithin A, go to https://www.timelinenutrition.com and use code UPGRADE10 to get 10% off the plan of your choice. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Go Deep on Relaxation & Sleep: https://balooliving.com/dave, use code DAVE for a special discount. Must-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount. Isometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona Plus. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… Robynne Chutkan, M.D., joins the show to talk about a topic that’s foundational to biohacking—resilience. More specifically, resilience that starts in the gut. You’ll learn:how your microbiome continually evolves and why that matters to the state of your gut and body functions.how to strengthen the antiviral defenses located in your gut.why your body’s own ability “to resist, heal, and recover from viruses is vastly superior” to pharmaceuticals.what to do before taking antibiotics to protect your gut, as well as what you can do to rehab your microbiome after antibiotic use.“Being on the winning team when battling viruses isn’t because of good luck, or coincidence, or variations in viral virulence,” Dr. Chutkan explains in her newest book, “The Anti-Viral Gut: Tackling Pathogens from the Inside Out.” "It’s due to differences in us, the hosts, and our defenses, and those differences are what determine your outcome. Put another way: it’s less about the potency of the pathogen and more about the health of the host.”Dr. Chutkan is a Yale- and Columbia-educated integrative gastroenterologist who’s been advancing knowledge and education about gut health for decades. Nearly 20 years ago she founded the Digestive Center for Wellness to help people get to the root issue of their digestive issues and improve their gut health. Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Brain Training with Sound & Vibration: Change unwanted behaviors, reduce negative self-talk, and enhance motivation and performance. Go to www.braintap.com/dave to get 30% offMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount.Get Fit in Five Minutes: https://www.carolbike.com, use code HumanUpgrade to get 2 years of free membership (a total savings of $360) on the CAROL Bike 2.0 and a 100-day home trial.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Eight Sleep sponsored this podcast.IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn about the intimate relationship between performance and sleep and how you can hack both with a combination of tech and lifestyle. Matteo Franceschetti joins the show to talk about high performance—something he experienced in athletics, business and life. He was a competitive athlete in his native Italy and a race car driver across Europe. He started two clean-tech companies on two continents. He also worked at the top tier of the international legal worldThe one thing he didn’t excel at was sleep. So, he co-founded Eight Sleep nearly a decade ago to hack sleep in all the ways that fuel human potential, performance and energy.Eight Sleep mattress and mattress pad technology redesign sleep with AI and machine learning models to track your nighttime biosignals. It’s a technology that’s catching the attention of professional athletes in sports like snowboarding, CrossFit, Formula One, and many more.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.eightsleep.com/dave/ to get up to $450 off a Sleep Fit Holiday Bundle that includes the Pod 3 Cover. This is a limited-time offer. Eight Sleep currently ships within the USA, Canada, the UK, Australia and select countries in the EU.Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Mattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProA Cleaner Nicotine Alternative: https://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozengesShield Yourself from EMFs: https://quantumupgrade.io, use code DAVE to get a two-week free trialSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

BiOptimizers sponsored this podcast.IN THIS EPISODE OF THE HUMAN UPGRADE™… you're going to get into bed with the topic of sleep. Pretty much everyone’s favorite. In this conversation, veteran biohacker and BiOptimers co-founder Matt Gallant returns to the show with some straight talk about how to get more and better sleep. He’s spent the big bucks—about $50K he estimates—exploring, experimenting and upgrading his own sleep. He's sharing what he now knows so you can create a sleep stack that supercharges your own energy.You’ll learn about the most common sleep disruptors and what to do about them. You’ll also learn to recognize sleep stages and how to improve your sleep pathways.This fun show uncovers the practical sleep devices, wearables, supplements and lifestyle hacks that will lull you to sleep. So many times, you’re tired and you know you want to go to sleep—and yet—your body and mind just don’t connect. The new Sleep Breakthrough makes that connection for you. And when cortisol runs amok and falsely perks you up with a second wind, you’ll know what to do. More and better sleep means you’ll be a higher-performing human. So, get some tonight!SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://sleepbreakthrough.com/dave and use code DAVE10 to get an extra 10% off. Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Better on Natural Memory Foam: https://myessentia.com/daveasprey, use code DAVE to get an extra $100 off an Essentia mattress purchase on top of Essentia’s Black Friday 25% off sale plus get two FREE organic pillows ($330 value) with mattress purchase. Through Nov. 27, 2022, only. Cooler Temps for Deeper Sleep: https://www.chilisleep.com/, use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep SystemMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discountSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Alitura Naturals sponsored this podcast.IN THIS EPISODE OF THE HUMAN UPGRADE™…… you’ll learn about skincare ingredients that can either nourish or harm your skin. You’ll find out about standards in skin care products, what “clean beauty” means, and what to look for on product labels.Andy Hnilo, founder of Alitura Naturals, joins the show to talk about skin fitness from the inside out and why using skincare products with ingredients found in nature is the way to go. That means things like pearls, meteorites, clay, CoQ10, enzymes and more.This conversation gets into ways you can get better skin by:choosing the right nutrient-rich specialty products you can apply topically; pairing natural skin products with other biohacks, like red light;making nutrition and fitness upgrades; andexploring supplements, peptides and other wellness options.Improving skin health also means avoiding fillers and chemicals. Toxins both in skin care products and the environment tremendously impact your skin. Acne no longer drives only teenage angst. Adult acne continues to rise, with women affected more than men. Acne affects more than 50% of women between the ages of 20 and 29 and more than 25% of women between the ages of 40 and 49. (American Academy of Dermatology 2012.) Andy himself struggled with acne—so he knows the toll it takes from outside appearance to inner emotional roil. So, he searched for answers: “It was the products that I was using and then also what I was ingesting,” Andy says. “What I was putting into and onto my body.”This get-smart guide to product ingredients, environmental awareness and lifestyle tips can help you find your own skin solutions. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://alitura.com and use code humanupgrade to save 20% sitewide.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Upgrade Your Air Quality: https://hypoair.com/Dave/Capture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideKickstart Autophagy: https://timelinenutrition.com/DAVE, use code ASPREY10 to get 10% off any planSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Analemma sponsored this episode.IN THIS EPISODE OF THE HUMAN UPGRADE™… you’re listening to a new Upgrade Spotlight series. Once a month, these shorter episodes feature guests who get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. Introducing Analemma! During this Upgrade Spotlight with Mario Brainovic, CEO of Analemma, you’re going to find out about a tool that transforms regular water into a supercharged, full-spectrum, coherent state. The kind of water you drink absolutely influences the quality of your life. You’ll learn the science behind Analemma and what it can do for your health and energy.Why water? You think you know the basics: stay hydrated daily, avoid plastic bottles and use a filtration system at home. Well, Analemma says water goes way beyond the basics—all the way down to your cellular level. You’re 70% water in body mass, but 99% water on a molecular level. You’re basically very clever water. The Analemma device—similar in looks and function to a magic wand—radically changes the state of drinking water. Environmental forces cause H2O molecules in drinking water to behave chaotically. At an atomic level, water molecules crash into each other constantly. Your body’s susceptible to that influence.“We found a way to bring order to this chaos,” Mario says. “When you swirl an Analemma through the water, what happens is that those same H2O molecules start forming a liquid crystalline structure. They start behaving harmonically. They, colloquially speaking, join hands.”Analemma water is not exclusion zone water. It's something different. “It also is structured water, but we came to it in a very different way,” Mario says. “The key element to it is its stability.”This conversation gets right into the science of Analemma and several studies. You’ll find out how:a new study is measuring the rise in ATP levels (in mitochondrial energy) when people drink this water.this water affects the human microbiome this water reduces your biological age by one to 12 years by regenerating your cellular system, according to GlycanAge.you get an instant balancing effect between the left and the right brain hemispherehow a cooling affect happens on your brainwaves almost instantly when drinking this waterthis water restores the biodiversity of infertile soilSPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://analemma-water.com and use code dave10 to save 10%.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… You’ll learn about the ways using a sauna can charge your energy, help you heal physical and mental health conditions—and science that backs that up. Sunlighten sponsored this episode.Connie Zack joins the show to talk about the far-reaching benefits of sauna use and what’s new in the field of infrared light. For more than 22 years, Connie and her husband, Aaron, have introduced infrared light therapy to 13 countries through Sunlighten. They’re leading innovations in infrared light therapy and infrared sauna manufacturing. This conversation covers a range of good things you’ll experience from using a sauna:how infrared light affects the body and triggers a biochemical cascade of benefits;how near infrared penetrates the body to interact with mitochondria;why the real magic of infrared combines both light and heat;what evidence connects infrared and detoxification—and why sweating wins;why you sleep better—without feeling exhausted—when you do a sauna session before bed;how infrared shows promising relief for those who experience depression; and practical ways to incorporate sauna into your own stack for better sleep and higher performance.Big takeaways for you:Sauna for Detox: Results from a blood-urine-sweat study support infrared for detoxification, and it’s more than just thermoregulation as traditional medicine often argues.Sauna for Depression: Chronic inflammation is associated with depression and may be a protective, inflammatory response involving thermoregulatory pathways, the immune system, serotonin system, heat shock proteins and more. Studies show that raising core body temperature can improve major symptoms of depression. Connie’s been on the show before, so check out Saunas Use Infrared to Power Detox, Immunity & Renewal – #823 to find out how infrared sauna helps you with immunity and recovery.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.sunlighten.com/dave to save up to $600 on your sauna purchase.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Brain Training with Sound & Vibration: https://specials.braintap.com/dave to get 30% offA Cleaner Nicotine Alternative: https://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozengesMattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™…Joe Polish, considered “the most connected person on the planet,” shares networking strategies that help you get what you want by giving people what they want.Dave Asprey recently connected with Joe in person to talk about Joe’s new book so you can use nine genius principles to turn your business—and your personal relationships—around. If you’re not asking “what’s in it for them?” when it comes to the people in your life—clients, colleagues, family and friends—you’re missing some important opportunities. Here are a few things you’ll learn from Joe’s new book, “What's in It for Them?: 9 Genius Networking Principles to Get What You Want by Helping Others Get What They Want,” as a how-to guide:Deepen rapport and connect with others by identifying and reducing their sufferingUpdate Dale Carnegie’s insights to win the right friends and influence the right peopleOvercome others’ intimidation tactics to find true appreciation in relationshipsBuild character for better results than capabilities can ever give on their ownUse basic marketing principles to find true loveProtect your efforts from the “takers” of the worldJoe did the hard work to heal from trauma and overcome addiction. He then spent years developing a genuine and generous approach to networking and building rapport. This approach propelled his business and led him to develop the Genius Network, one of the world’s most impactful networking groups for high-achieving entrepreneurs.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Harness Cold to Improve Health & Performance: https://www.cryobuilt.comCustomized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave, use code DAVE10 to get 10% off. Learn more on The Human Upgrade podcast: Hack Your Neurochemistry with Customized Nootropics – Mr. Noots & Matt Gallant – #861Business Growth With SEO: https://www.stephanspencer.com, get a FREE consultationSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this Episode of The Human Upgrade™...​ Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.• How (and why) brain cells transfer mitochondria to one another• How a newly discovered molecule stimulates hair growth• How a tired brain drives poor decision-makingEPISODE SPONSOR: The Eng3 NanoVi device helps repair oxidative stress damage and support the body’s natural repair mechanisms.https://eng3corp.com/DAVE/. Learn more: The Anti-Aging Science Behind the NanoVi Device – Rowena Gates & Hans Eng – #416.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn how a yoga practice can be a vehicle for inner transformation. This conversation looks past the popularity of yoga as a fitness trend and into its deeper potential for human development. You’ll also learn how yoga can be a way for you to explore your whole being—from physicality to emotions to thinking.“A yoga practice often can be the missing ingredient for people,” says renowned yoga master Baron Baptiste. “Often I hear, ‘I added yoga practice to my routine and regimen, and it just shifted everything for me.’ It's a very different way of working your body, mind and breath integration.”Baron devotes his own life to the study and practices of human development. For more than 30 years, he’s facilitated education through yoga principles and teachings.His power vinyasa yoga— The Baptiste Methodology—includes the physical (asana), meditation (dhyana) and inquiry (niyama). “Iyengar was one of my primary teachers,” Baron says. “One thing I borrowed from him is the rigor to a body alignment—a True North Alignment.”Baptiste Yoga is a systematic approach made up of 53 poses, or asanas, that are linked together by connective momentum and consist of five classical pillars: Drishti (gaze), ujjayi (breath), bandhas (foundation), tapas (heat) and vinyasa (flow).More about Baron Baptiste: Baron began to seriously study yoga at age 12. As the son of two of America's yoga pioneers, he’s got a great life story that highlights the transformative power of yoga. He trained extensively in all the major traditions before beginning to teach yoga in Los Angeles in the late 80s and creating Baptiste Power Vinyasa Yoga in the mid-90s. He’s worked with celebrities, Olympians and professional athletes. He founded the Baptiste Power Yoga Institute that reaches people around the world. Baron’s also a New York Times bestselling author of multiple books, Emmy-award film maker and public speaker.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Hydrate with Electrolytes: https://DrinkLMNT.com/DAVE, get a FREE LMNT Sample Pack with 8 single-serving packets for the cost of shipping ($5 for U.S. customers) A Cleaner Nicotine Alternative: https://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozengesCustomized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave, use code DAVE10 to get 10% off.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… biohacking goes in a different direction. This frank discussion looks at the dying process and how people and those close to them (family and friends) experience death. You’ll learn about the existence of angels and the power of psychic abilities—even if you may be a skeptic. The conversation also explains what a “medical intuitive” does and how a medical intuitive facilitates energetic healings.Cool show today! And not what you might expect.Avid biohacker Julie Ryan checks a lot of success boxes: businesswoman, serial entrepreneur, author, radio show host and podcaster. She also invents surgical devices that sell globally; some have been on the market for three decades. She’s founded nine companies in five different industries. She checks a lot of unconventional boxes, too. She’s a psychic and medical intuitive. This means she can sense medical conditions and illnesses in people—like a human MRI machine. Then she facilitates energetic healings and says she does a lot of work with stem cell energy.Julie scans animals, accesses people’s past lives and senses how close to death someone is. She communicates with spirits both alive and dead. Even cooler—Julie’s psychic and medical intuitive skills are learned and she teaches those skills to others.Julie talks about the “glorious” side of dying, a process that she says involves angels, multitudes of deceased family and friends, the spirits of deceased pets, and countless serendipitous (and miraculous) moments that are all part of a prescribed series of events. She calls this the “12 Phases of Transition™” and broadly outlines this in today’s episode.SPECIAL OFFERS FOR THE HUMAN UPGRADE LISTENERS: Julie’s giving a digital or audio copy of her books to every listener who wants one. Go to https://askjulieryan.com/ask-julie/. Mention you heard Julie on this podcast and would like a copy.“Angelic Attendants: What Really Happens As We Transition From This Life Into The Next” or “Angel Messages For Kids” or “Angel Messages For Dogs” or “Angel Messages For Cats”WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Shield Yourself from EMFs: https://quantumupgrade.io, use code DAVE to get a two-week free trialMattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProProbiotic Eases Stress: https://www.omnibioticlife.com/DAVE, use code DAVE20 to get 20% off. Learn more:: Upgrade Spotlight: Probiotics to Power the Gut-Brain Axis – Keri Glassman, MS, RD, CDN / Omni-Biotic – #974See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Prenuvo sponsored this episode.IN THIS EPISODE OF THE HUMAN UPGRADE™... you’ll find out about a new healthcare model that’s putting you fully in control of your health with whole-body MRI scans. Dr. Raj Attariwala, Prenuvo’s founding radiologist, joins the show to explain how Prenuvo gives you early insight into what’s going on under your skin. His Ph.D. in Biomedical Engineering and medical degree in Nuclear Medicine and Radiology informed how he created Prenuvo’s whole-body MRI device software. Here’s what Prenuvo’s scans can do:detect nine of the 10 top cancers in stage one detect nearly 500 other medical conditions look at degeneration of the spine and body compositionlook at the blood in the brain and the blood vessels in the center of the brainDave visited Prenuvo’s new Los Angeles facility right before the start of the 8th Annual Biohacking Conference in Beverly Hills to talk with Dr. Raj about Prenuvo’s innovative take on the MRI scan. With AI, Prenuvo’s bringing in quantitative reproducibility, which means you can start to see subtle changes throughout your body over time.In this conversation, you’ll learnWhy it’s so important to know your health baseline instead of waiting for symptoms to present and disease to progress. The reactive medical system in the U.S. focuses on disease management after it occurs. What types of medical issues show up that may be overlooked or dismissed by your primary care doctor or other medical professionals. Existing annual checkups are relatively useless.How Prenuvo’s whole-body MRI scans can give you an “age score” for your physiology that you can track over time. This means you can make proactive, informed decisions about your own health.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Get a $300 discount off Prenuvo’s Whole Body Scan ($2,199 instead of $2,499). You’ll get your scan images and radiologic analysis via your smartphone app or the web. Book online: https://prenuvo.com/DAVE or book via phone: 1-833-PRE-NUVO (1-833-773-6886); mention code “DAVE." This discount is valid through March 10, 2023, in all Prenuvo clinics throughout the U.S. and Canada.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Business Growth With SEO: https://www.stephanspencer.com, get a FREE consultationCustomized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave, use code DAVE10 to get 10% offControl Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipment. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… menopause and the perimenopausal years leading up to it take the spotlight as a topic frequently requested by listeners. Great timing! It’s World Menopause Awareness Day Oct. 18 and World Menopause Awareness Month in October.More than 1 million women in the United States experience menopause each year. Still, little is known, researched or taught in medical schools about the health effects of this natural biological occurrence.Guys who love the women in their lives and younger women will get a lot of benefit out of the show, too, and come away armed with information. Note that some women go through menopause at ages earlier than 40 for various medical reasons and will want to keep listening.“I want people to stop being afraid to say menopause,” says Dr. Suzanne Gilberg-Lenz. “I think there's a lot to be said for just saying the word out loud. If we can deweaponize the term and just be talking about it like we would any other life phase, then we can be there for each other and we can also learn from each other.”Dr. Suzanne, an OBGYN board certified in integrative and holistic medicine, brings her expertise to the show to tackle this complex topic. Her “endless curiosity about the human experience” propelled her to uncover ways to ease women through menopause stages with effective tools. She looks at the science and also brings in holistic elements, including Ayurveda.  For more than two decades, she’s led women through life transitions. Her new book “Menopause Bootcamp: Optimize Your Health, Empower Your Self and Flourish as You Age” offers practical steps and solutions that can help women navigate the many menopausal changes they may experience. Some of what you’ll learn in this extensive conversation:Ways to de-pathologize menopause—which contributes to healing ageism.What’s actually going on with your hormones during the transition to menopause and beyond.Why hormone testing isn’t all that useful.Why Menopausal Hormone Therapy (MHT and what used to be called hormone replacement therapy, or HRT)—continues to be misunderstood and controversial.How to craft specific questions to better advocate for yourself with doctors.How to recognize symptoms that can range from moderate to severe to even debilitating.How to manage symptoms that disrupt the activities of daily living and long-term health.How physical changes can drive mental health issues during this time of your life.How to take control of your symptoms and find real solutions.Dr. Suzanne’s “Menopause Bootcamp” touches on prejudice in medicine and how to break free from the societal bullshit surrounding menopause so you can get appropriate help and treatments.Calm Your Nervous System with a Weighted Blanket:: https://balooliving.com/dave, use code DAVE for a special discountIsometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona PlusBrain Training with Sound & Vibration:  www.braintap.com/dave to get 30% offSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™... kava expert and founder of TRU KAVA, Cameron George, joins the show to share new information about the many body/mind benefits you can get from kava.TRU KAVA sets the industry standard for kava quality, safety and education. On episodes #731 and #859, we talked about kava’s historical origins and uses, how it can be safely consumed, and how it’s extracted and processed today.You can use kava for both energy and sleep. It’s also a natural alternative to recreational alcohol and drug use. “It's like a calm, enhanced state of natural sobriety,” Cameron says.If you struggle with social anxiety, kava’s roots in community and social connection can improve your relationships, too.Today’s conversation further expands the kava discussion.“Kava is a stress-relieving nootropic,” Cameron says. “It's a natural elixir that's prepared from the roots of a plant that grows in the South Pacific. Indigenous people have used it for thousands of years and prepared this food-grade drink kind of like coffee. On the stress-relieving side, on the nootropic side, they've prepared it and used it in almost every context imaginable, weddings, funerals, spiritual ceremonies, social gatherings. It helps to open up the opportunity for human connection, but it also helps to get people focused yet relaxed and calm and in a very safe space neurologically.”Kava studies show promise for people who may be experiencing mental health issues. You’ll learn about kava’s potential to transform mental health care and its therapeutic applications for mental/trauma-related illnesses. Kava works on a psychological, emotional and physiologic level.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: http://www.trukava.com/, use code DAVE15 to get 15% off all productsWE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Science-backed, Music-driven Breathwork: Go to https://www.othership.us/dave, sign up for the app and get two weeks FREE.Isometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona PlusCustomized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave, use code DAVE10 to get 10% off. Learn more on The Human Upgrade podcast: Hack Your Neurochemistry with Customized Nootropics – Mr. Noots & Matt Gallant – #861See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn how botanical remedies treat infectious and inflammatory diseases. You’ll get a fascinating look at how plants and microbes interact and how antibiotic resistance evolves. And you’ll meet a leader in the field of medical botany who travels to remote locations and communities around the globe seeking out modern medicines from plants. Medicinal plants make up the primary form of medicine for 70–95 percent of people living in most developing countries. At least 4 billion people are dependent on plants for medicine.Ethnobotanist Cassandra Quave, Ph.D., is an herbarium curator and associate professor of dermatology and human health at Emory University. (She’s also a writer, speaker and podcast creator/host.) She teaches courses on medicinal plants, food, and health and her Quave Research Group leads anti-infective drug discovery research initiatives. Dr. Quave’s also the co-founder and CEO/CSO of PhytoTEK LLC. This drug-discovery company works to develop solutions from botanicals. In particular, they look at treatments of antibiotic-resistant infections like MRSA.Her battle with MRSA is personal. She was born with congenital skeletal deformities and had her leg amputated at age 3. She nearly died from a staph infection that infection required more amputation. Her early life and disability experiences shaped her life’s work with medicinal plants.She chronicles her extraordinary life, field work and scientific discovery in her book, “The Plant Hunter: A Scientist’s Quest for Nature’s Next Medicines.” Plants are incredibly complex, and science has barely scratched the surface, Cassandra says. “Some of our best drugs for infection, cancer and pain were originally found in plants,” she says in her book. “Even though they may be produced in a factory setting now, the original chemical blueprints came from plants.”Cassandra studied pre-med in college with a double major in biology and anthropology. She couldn’t find a connection between the two fields until she journeyed to the Amazon where she studied with a local shaman/healer who relied on plants as medicine. She realized instead of going into the practice of medicine, her true path was the discovery of new medicines from nature.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Cooler Temps for Deeper Sleep: https://www.chilisleep.com/, use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep SystemKickstart Autophagy: https://timelinenutrition.com/DAVE, use the code ASPREY10 to get 10% off any planCapture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Othership sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™…you’re listening to a new Upgrade Spotlight series. Once a month, these shorter episodes feature guests who get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. Introducing Othership! During this Upgrade Spotlight, you’ll find out how Othership’s breathwork app teaches you ways to manage your most prevalent stressors. Things like tension, anxiety, overwhelm, processing emotions, irritability, trouble sleeping, low energy, nervous system dysregulation or mental health issues. When you begin to regularly incorporate breathwork into your life, you notice and feel the emotional, mental and physical differences right away. Breathwork is a visceral, physiological shift that you can reach in under five minutes. It’s the perfect primer to bring you into a meditative state, with even more physical benefits. BONUS! You can experience this shift by following along with the live demo in this episode led by Othership co-founder, Robbie Bent. (Make sure you’re not driving!)Robbie joins the show to talk about the power of adding a breathwork practice to your everyday routine. If you’ve tried meditation and it wasn’t your thing, or you struggle with consistent mindfulness, the Othership app gives you lots of options to find what fits.You can access more than 500 guided breathwork sessions within three styles: up, down and explorer. Othership combines breathing techniques and guided meditations created by psychotherapists, wellness practitioners, hypnotherapists, artists and DJ’s, spiritual teachers and life coaches. The sessions are music-driven, science-backed and curated by expert facilitators. The Othership app helps you build and sustain a new mindfulness routine – all through the power of your breath. Whether you have time to practice for one minute, or 60, you’ll be able to shift your state in a session style that works best for you, such as:Deep breathing + breathworkGuided meditationAffirmations + visualizations Sound healingHypnosisSomatic release therapyVocal toningIntention settingSelf-massage + stretchingMovement + danceMind-body connectionMindful walking + working SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Visit https://www.othership.us/partnerships/dave-asprey and get a two-week FREE app trial.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

(BrainTap® sponsored this episode.)IN THIS EPISODE OF THE HUMAN UPGRADE™… brain expert Patrick Porter, Ph.D., joins Dave at the 8th Annual Biohacking Conference in Beverly Hills to talk about training your brain. Dr. Porter pioneered the use of brainwave entrainment with a technology-enhanced meditation device called BrainTap.Whether you’re a newbie, a hard-core devotee or somewhere in the middle of your biohacking journey, you already focus on body exercise and nutrition. You probably manage your stress and mental health, too. It’s all training of some sort, which is where BrainTap comes in. It’s a specific kind of training for your brain.New discoveries in science reveal that you can form new neurons in your brain, called neurogenesis. Your brain state isn’t fixed! And then there’s neuroplasticity, a process of adaptive structural and functional changes to the brain that involves connections to your nervous system.BrainTap’s unique technology uses light, sound and vibration to train and regulate your brain for relaxation, sleep, performance, weight loss, aging and more. To get to a higher personal frequency on the regular, you want to achieve coherence.Since Dr. Porter specializes in the science of calming the brain, you’ll find out how you can manage your physiological and mental health in today’s super stressed-out world. You’ll also learn how impact remote work, remote learning and pandemic isolation impacted brain health and memory.This conversation gets into some of BrainTap’s exciting research with aging populations and elite athletes. too.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://braintap.com/daveWE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Isometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona PlusMattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProA Cleaner Nicotine Alternative: https://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozengesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn how you can make smarter food choices to support your metabolic energy and upgrade your brain. You’ll also find out some new things about body fat. For example, did you know that it’s a complex organ that communicates throughout your entire body system? You’ll get tips on fat loss essentials and how to use them to your advantage. Today’s guest, Shawn Stevenson, hosts a popular podcast called The Model Health Show. He’s a nutritionist, researcher and bestselling author with education and experience in business, biology, and nutritional science.Shawn’s been in the health and wellness space and doing clinical work as a nutritionist for nearly two decades. He’s known for his ability to keep learning and evolving his approach with deep research into the science of human health.He’s all about improving human performance and energy with science-backed basics like food in his “Eat Smarter” book and sleep in his “Sleep Smarter“ book. This episode gets right into food choices you can make—and why they work—to stoke your metabolic energy. Topics like:How people can better understand the process of fat loss.How the misconstrued science of calories contributes to how much people struggle with their diets.What metabolic switches are, what do they do, and why it’s important for you to know how to turn them on and off.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Custom Silver for Health & Healing: https://tru47.com/dave, use code DAVE20 to get 20% off for a limited timeCustomized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave, use code DAVE10 to get 10% offBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultationSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this Episode of The Human Upgrade™...​Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.• Saving your poop may save your microbiome• Insults trigger a mini slap in the face• Young cerebral spinal fluid supports memory in aging brains• The distinct role your nose plays in your friendshipsEPISODE SPONSOR: Get Fit in Five Minutes: Go to https://www.carolbike.com. Use code HumanUpgrade to get 2 years of free membership (a total savings of $360). CAROL Bike also offers a 100-day home trial of the CAROL Bike 2.0. Learn more: How to Hack Your Cardio Workout – Ulrich Dempfle– #978.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

BodyBio sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn how butyrate and phospholipids keep your gut, cells and brain performing at their best. You’ll find out how your mucosal barrier defends against pathogens in your gut microbiome. You’ll also learn about discoveries in the field of cell membrane medicine. This focus determines how your body functions now and also how you age.Jessica Kane Berman joins the show to share new information and interesting science about cellular health from the perspective of BodyBio, the company founded by her grandfather, Ed Kane, an inventor, health explorer and early biohacker. He went looking for answers to his own health issues in the 1980s and got deep into the science of fatty acid research and cell membrane medicine through blood testing.BodyBio sticks to a very specific group of products, most notably butyrate and a phospholipid complex of phosphatidylcholine. Jess explains how true liposomal phosphatidylcholine and phospholipids get through to the cells to help rebuild that membrane. Here’s a few good things butyrate does in your gut:Helps maintain the thickness of the mucosal barrier—keeps the good in and the bad outHelps the expression of tight junctions and strengthens the gut wallExpresses MUC2: this produces mucus, which thickens your mucous liningRegulates T-Cells and helps lower cytokine releaseIncreases microbiome diversityAnti-inflammatory properties help improve intestinal barrier function and mucosal immunityButyrate goes way beyond the gut to influence bone mass and density, asthma and allergies, histamine intolerance, body detoxification, inflammatory brain pathways, and mitochondrial function. Butyrate also can alter gene expression, protect against cancer, and regulate the body’s immune system.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://bodybio.com/dave, use code DAVE25 to get 25% offWE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Cooler Temps for Deeper Sleep: https://www.chilisleep.com/, use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep SystemIsometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona PlusShield Yourself from EMFs: https://quantumupgrade.io, use code DAVE to get a two-week free trialSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this Episode of The Human Upgrade™...​ Dave talks about what could be causing brain fog with a podcast guest in this impromptu intervention. Keri Glassman, MS, RD, CDN, recently spoke about gut health as the expert for Omni-Biotic probiotics. During the interview, she was searching for a word and got frustrated she couldn’t grasp it quickly. This intervention looks at the potential culprits responsible for Keri’s brain fog and memory hiccups: ThyroidHormones, such as testosterone and DHEAPerimenopauseMast cell-mediated inflammationCortisol & stressADHDMold toxinsMercury & leadKeri is a registered dietitian, certified nutritionist, healthy cooking expert and author of four books. She also founded Nutritious Life, a lifestyle and media company and Nutritious Life Studio, an online education platform focused on nutrition, coaching, and business.Find tips and resources on the episode webpage.Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.WE APPRECIATE OUR PARTNERS, CHECK THEM OUT!Nature’s Nootropic: https://trukava.com, use code DAVE15 to get 15% offBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultationMattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™…a legacy upgrade conversation with Dr. Joe Dispenza explores how you can change from the inside out through a combination of neuroscience, epigenetics, quantum physics—and even a divine source. “I teach people the science of changing their mind and what it is to truly transform,” he says.He shows people how to rewire their brains and recondition their bodies to make lasting changes by way of science, energy and mysticism. His background and expertise include training in neuroscience, neurology, cellular biology, brain function and chemistry, memory formation, and aging and longevity.From healing illness to evolving consciousness, Dr. Dispenza examines how to connect with the divine and bridges the mystical with science. “It's really important to have science demystify that process,” he says. Why? Because science is a contemporary language that offers you explanations, helps you understand the how and why, and assigns clear meaning. “Here's what I know,” Dr. Dispenza says. “We have evidence that you can make your brain work better. As you can prove also, we have evidence that you can make your heart work better. We have evidence, you can strengthen your immune system. We have evidence, you can change your gene expression in four days. We have evidence, you can lengthen your life from meditation, just by lengthening your telomeres and changing your state. We have evidence in the scientific world that people actually can transform.”Listen on to learn about the power of inner work, elevated emotions and human connection.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!A Cleaner Nicotine Alternative: https://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozengesCustomized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave, use code DAVE10 to get 10% off. Learn more on The Human Upgrade podcast: Hack Your Neurochemistry with Customized Nootropics – Mr. Noots & Matt Gallant – #861Probiotic Eases Stress: https://www.omnibioticlife.com/DAVE, use code DAVE20 to get 20% off. Learn more on The Human Upgrade podcast: Upgrade Spotlight: Probiotics to Power the Gut-Brain Axis – Keri Glassman, MS, RD, CDN / Omni-Biotic – #974See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn about a “6 Phase Meditation” approach that absolutely everyone can do—and benefit from!—no exceptions. This custom-designed meditation sequence gets you into a peak state in just a few minutes. No boredom, special breathing, or clearing your mind required. You’ll find out how to make meditation work for you and how you can use intuition as one of your greatest strengths.Episode guest Vishen Lakhiani took up meditation at age 26 as a way to cope with the stress of working for a startup in Silicon Valley. That decision changed his life so dramatically that within two years he quit to pursue meditation, other tools of personal development, and then spread awareness and education to people around the world. He’s taught his signature 6-phase meditation style to world-class athletes, professional entertainers and high-performers in all types of business. He also founded Mindvalley, an international learning platform.Vishen’s newest book, “THE 6 PHASE MEDITATION METHOD: The Proven Technique to Supercharge Your Mind, Manifest Your Goals and Make Magic in Minutes a Day,” outlines a series of science-backed mental exercises for accomplishing your goals. It condenses the wisdom of nearly 1,000 neuroscientists, monks, yogis, and meditation experts into a hyper-efficient programming script that you can run through your mind any time of day.Unlike traditional meditation that encourages a calm and serene environment, the 6 Phase Meditation Method can be done from anywhere—your bed, your office or even on your next flight. “It's six different practices that you layer on that put you in a hyper-optimized state,” Vishen says. You’ll get a lot out of this fascinating conversation that gets into realms of spirituality, psilocybin, perceptual diversity, physics, brain waves, and altered states. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Mindvalley.com/books/6phaseWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Shield Yourself from EMFs: https://quantumupgrade.io, use code DAVE to get a two-week free trialStructure Water Molecules; Achieve Body/Brain Coherence: https://analemma-water.com, use code DAVE10 for 10% offIsometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona PlusSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

CAROL Bike sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll learn about new research that’s pinpointing the most effective cardio workouts. You’ll find out that you can do a cardio workout in just 15 minutes a week and still increase your cardiovascular fitness. You’ll also get an introduction to the new CAROL Bike 2.0 and its upgraded great features.Ulrich Dempfle, MBA, Chief Product Officer, CEO and co-founder of CAROL Bike, returns to the podcast with exciting new research results. CAROL’s REHIT (Reduced Exertion HIIT) workout retained all its effectiveness yet cut its time nearly in half—from 8 minutes and 40 seconds to five minutes.CAROL Bike continues to innovate fitness and prove that more or longer sprints aren’t better. “What matters is that you sprint at your personalized maximum intensity, switching from zero to max in a fraction of a second,” Ulrich explains.  An investment of only 5 minutes, 3 times a week means you can reap powerful cardiovascular benefits, even gain strength, and get on with your other biohacks.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.carolbike.com. Use code HumanUpgrade to get 2 years of free membership (a total savings of $360). CAROL Bike also offers a 100-day home trial of the CAROL Bike 2.0.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Harness Cold to Improve Health & Performance: https://www.cryobuilt.comSleep Better on Natural Memory Foam: https://myessentia.com, use code DAVEVIP to get an exclusive discount. Learn more on The Human Upgrade podcast: Mattress Smarts 101 for High-Performance Sleep – Jack Dell’Accio – #875Customized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave, use code DAVE10 to get 10% off. Learn more on The Human Upgrade podcast: Hack Your Neurochemistry with Customized Nootropics – Mr. Noots & Matt Gallant – #861See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.