The Dr. Hyman Show

This episode is brought to you by Eight Sleep and Athletic Greens. Sugar is the number-one thing we can all use less of in our lives—in fact, just thinking about it releases insulin! Sugar turns on many mechanisms of disease and death, including inflammation. It fuels cancer and heart disease, it drives hormonal changes, it slows metabolism, and it literally shuts down the body’s ability to burn fat. On top of all that, sugar is highly addictive: the more we eat, the more we want. In this episode of my Masterclass series, I am interviewed by my good friend and podcast host Dhru Purohit about why sugar is so harmful to our health, why the type of sugar really doesn’t matter, and much more. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top-50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Eight Sleep and Athletic Greens. Eight Sleep’s Pod Pro mattress is so smart that it adjusts your temperature and also gives you individualized recommendations on how to sleep better the next night. To get yours, go to eightsleep.com/mark to check out the Pod Pro mattress or mattress cover and save $150 at checkout. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. In this episode, we discuss (audio version / Apple Subscriber version): Why sugar is so detrimental to your health (4:39 / 1:04) Sugar dosage and how it compounds throughout the day (11:45 / 8:20) Are healthier sugar options really any better? (15:53 /11:23) The many different types of sugar (19:43 / 16:02) What to look for to see how your body responds to sugar, including labs (28:21 / 24:35) Questions from our community, including the impact of sugar on the microbiome, fungal overgrowth, natural food-based sugars, and more (37:20 / 33:46)

This episode is brought to you by ButcherBox, Athletic Greens, and Rupa Health. Eliminating starch and sugar could be the most powerful food choice you make to improve your health and increase your longevity. Why? Because it can reduce or eliminate insulin resistance, which is behind so many chronic diseases. Add to that reducing stress and sleeping better, and you're on the way to a healthier lifestyle that benefits both your body and your mind. In five clips from my Masterclass series, Dhru Purohit and I discuss the basics of Functional Medicine, including diet, inflammation, stress, and sleep, and why it's important to start reducing chronic disease right now to live a longer, healthier, vitality-filled life. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top-50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by ButcherBox, Athletic Greens, and Rupa Health. For a limited time, new subscribers to ButcherBox will receive free ground beef for life. When you sign up today, ButcherBox will send you 2lbs of 100% grass-fed, grass-finished beef free in every box for the life of your subscription. To receive this offer, go to ButcherBox.com/farmacy. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.

This episode is brought to you by Rupa Health, Eight Sleep, and Cozy Earth. Just five years ago, the concept of age reversal was considered crazy. Now, it’s the hottest topic in research, as we continuously discover exciting interventions that can actually reverse our biological age. I’ve experienced these amazing advances firsthand—chronologically I’m 62, but my biological, or “inner” age, is only 39. And I’m not the only one who’s become fascinated by the science of age reversal and reaped the benefits. Today on The Doctor’s Farmacy, I talk to Tony Robbins and Peter Diamandis about their research and personal journeys in aging backwards using a range of simple, accessible interventions and the latest health-tech. Tony Robbins is an entrepreneur, #1 New York Times bestselling author, and philanthropist honored by Accenture as one of the top 50 business intellectuals in the world. Through his philanthropy and partnership with Feeding America, he has provided more than 800 million meals and is on track to provide 1 billion meals by 2025. Peter Diamandis is the founder and executive chairman of the XPRIZE Foundation, which leads the world in designing and operating large-scale incentive competitions. He was recently named by Fortune as one of the “World’s 50 Greatest Leaders.” He is also the executive founder of Singularity University, a graduate-level Silicon Valley institution that counsels the world's leaders on exponentially growing technologies This episode is brought to you by Rupa Health, Eight Sleep, and Cozy Earth. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. Check out a free, live demo with a Q&A or create an account here. Check out Eight Sleep’s Pod Pro mattress or mattress cover and save $150 at checkout here. Right now, get 40% off your Cozy Earth sheets with the code MARK40 here. Here are more details from our interview (audio version / Apple Subscriber version): The physical injury that inspired Tony to write this book (5:45 / 3:12) Redefining our concept of aging (19:10 / 16:00) Understanding how to modify genes to reverse aging (21:10 / 17:52) New diagnostic testing to inform us about our health (36:36 / 31:54) Simple ways to enhance your longevity and health (45:01 / 41:19) Sleeping, eating, and fasting for longevity (48:05 / 43:14) Exercising for longevity (54:08 / 49:33) How mindset affects aging and longevity (1:00:20 / 55:35) Three things that lead to emotional mastery (1:06:31 / 1:03:38) Nutraceuticals, supplements, medicines, and other new therapies to enhance health and longevity (1:13:06 / 1:08:21) Get a copy of Life Force: How New Breakthroughs in Precision Medicine Can Transform the Quality of Your Life & Those You Love at https://www.tonyrobbinslifeforce.com/. Sign up for the Longevity Insider Newsletter at https://longevityinsider.org/.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content. Show Notes: Dr. Hyman’s COVID Blog

This episode is brought to you by Rupa Health and Paleovalley. Belly fat, or visceral fat around the organs, is the number-one cause of aging. It drives inflammation, increases the risk of blood clots, changes your hormones and brain chemistry, and more. It’s a recipe for disaster in the body. Not only does belly fat surround the organs, but it’s an organ of its own that produces dangerous inflammatory cytokines that may lead to a cytokine storm. In short, we want to do everything we can to avoid belly fat. In this episode of my Masterclass series, I am interviewed by my good friend and podcast host Dhru Purohit about belly fat, or visceral adipose tissue. We discuss how this form of fat is the most dangerous and why it’s so important to take steps to reduce it. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top-50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and Paleovalley. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. In this episode, we discuss (audio version / Apple Subscriber version): Top foods that lead to belly fat (4:13 / 1:08) Why belly fat is so bad for us (7:01 / 4:06) The effects of liquid sugar and calories (13:03 / 9:44) The connection between belly fat and heart disease (15:21 / 11:57) How belly fat affects your brain and could lead to Alzheimer’s and dementia (18:43 / 15:16) Why it’s not your fault you have belly fat (20:37 / 17:16) Case study of a 65-year-old woman (28:01 / 24:55) Questions from our community, including belly fat after menopause, late-night eating, the impact of stress, and more (31:16 / 28:18) Mentioned in this episode: Janice’s Story

This episode is brought to you by Eight Sleep, Athletic Greens, and BiOptimizers. You can start to heal your body right now simply with the food you put in your mouth—it's really that simple. Food has the power to heal the body from many ailments and can even help prevent cancer. There are many powerful medicinal compounds in foods: curcumin, catechins, lycopene, resveratrol, and quercetin, just to name a few. That’s why I call the grocery store the drug store; we can literally eat our medicine at every meal. In this compilation episode, I am joined by Dr. William Li to discuss how to use food as medicine, the importance of nitric oxide for our blood vessels, the role of the microbiome, and why it's necessary to support the immune system. William Li, MD, is a world-renowned physician, scientist, speaker, and author of Eat to Beat Disease: The New Science of How Your Body Can Heal Itself. He is best known for leading the Angiogenesis Foundation. His groundbreaking work has impacted more than 70 diseases including cancer, diabetes, blindness, heart disease, and obesity. His TED Talk, “Can We Eat to Starve Cancer?” has garnered more than 11 million views. An author of over 100 scientific publications in leading journals such as Science, the New England Journal of Medicine, The Lancet, and more, Dr. Li has served on the faculties of Harvard, Tufts, and Dartmouth Medical School. This episode is brought to you by Eight Sleep, Athletic Greens, and BiOptimizers. Eight Sleep’s Pod Pro mattress is so smart that it adjusts your temperature and also gives you individualized recommendations on how to sleep better the next night. Go to eightsleep.com/mark for exclusive President’s Day savings through February 22, 2022. Now shipping to the U.S., Canada, and the UK. ​ AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. BiOptimizers Magnesium Breakthrough formula contains seven different forms of magnesium, all of which have different functions in the body. There is truly nothing like it on the market. Go to magbreakthrough.com/hyman and use code hyman10 at checkout for 10% off your next order. You can find my full-length conversations with Dr. William Li here: Eat This to Starve Cancer and Prevent Disease Today Eat This To Heal The Body & Never Get Sick Again

This episode is brought to you by Rupa Health, Thrive Market, and Cozy Earth. Uric acid is a central player in metabolic mayhem. Despite its long association with gout and kidney stones, it’s involved in so much more—especially our metabolic disease epidemic. There are three things that raise our levels of uric acid: purines, alcohol, and fructose. The latter is the biggest challenge, due to its overwhelming presence in our Standard American Diet. That doesn’t mean all fruit is bad or even that all alcohol and purine-rich foods have the same effect. Like all parts of health and nutrition, there are nuances we need to consider to create optimal health. That’s why I’m so excited to take a deep dive into the topic of uric acid with my friend and colleague Dr. David Perlmutter. Dr.Perlmutter is a Board-Certified Neurologist and five-time New York Times bestselling author. He serves on the Board of Directors and is a Fellow of the American College of Nutrition. He is the author of Grain Brain among others, and his new book, Drop Acid was just released. Dr. Perlmutter received his M.D. degree from the University of Miami School of Medicine where he was awarded the Leonard G. Rowntree Research Award. He serves as a member of the Editorial Board for the Journal of Alzheimer’s Disease and has published extensively in peer-reviewed scientific journals including Archives of Neurology, Neurosurgery, and The Journal of Applied Nutrition. This episode is brought to you by Rupa Health, Thrive Market, and Cozy Earth. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account here. Thrive Market is an online membership-based grocery store that makes eating well convenient and more affordable. Join today to receive an extra 40% off your first order and a free gift worth over $50 here. Cozy Earth makes the most comfortable, temperature-regulating, and nontoxic sheets on the market. Right now, use code MARK40 to get 40% off your Cozy Earth sheets here. Here are more details from our interview (audio version / Apple Subscriber version): What is uric acid and how does it affect our health? (5:30 / 2:00) The impact of fructose consumption on our physiology (11:45 / 8:10) The differences between fructose and glucose (19:20 / 16:29) Why high fructose corn syrup is used in so many foods (21:13 / 17:40) The three sources of uric acid (22:57 / 19:23) Fructose consumption, uric acid, and gut health (28:19 / 23:43) How to eat to reduce uric acid (33:54 / 28:52) Medications that increase uric acid (47:07 / 42:04) Uric acid and Alzheimer’s (50:28 / 45:28) Heavy metals, supplements, sleep, exercise, and uric acid (54:12 / 49:14) Get Dr. Perlmutter’s new book, Drop Acid: The Surprising New Science of Uric Acid—The Key to Losing Weight, Controlling Blood Sugar and Achieving Extraordinary Health here.

This episode is brought to you by Rupa Health and Mitopure. Between 20 and 30 percent of all doctor visits are initiated due to lack of energy, or chronic fatigue. It is a common problem that plagues so many of us. Often we don’t realize that the last thing we want to do—exercise—could be an easy solution to increasing our energy levels. When we create stress in the body from exercise or other stressors, also called hormesis, we can actually build back stronger as the body heals and repairs. In this episode of my new Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about all the things we can do to improve our energy levels. We also talk about how caffeine and sugar in your diet impact energy, as well as answer questions from our community about the value of napping, if MCT oil increases energy, and why fruit juice is not a great choice. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and Mitopure. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Mitopure is the first and only clinically tested, pure form of a natural gut metabolite called urolithin A that clears damaged mitochondria away from our cells and supports the growth of new, healthy mitochondria. Get 10% off at timelinenutrition.com/drhyman with code DRHYMAN10. In this episode, we discuss (audio version / Apple Subscriber version): Three things we can do to improve our energy levels (4:37 / 00:50) Three things that zap your energy (8:17 / 4:29) Steps to evaluate chronic fatigue (12:34 / 7:02) How to reduce fatigue and increase energy (15:37 /11:43) Evaluating caffeine consumption and if it works for you (18:24 / 14:17) Why blood sugar management is important for optimal energy (20:42 / 16:49) What I do to support my energy level (27:22 / 23:25) Questions from our community (39:26 / 35:37) Mentioned in this episode: Try This: Why You Need a Coffee Break and How to Do It New Barn Organics Almond Milk OmegaQuant Levels

This episode is brought to you by Rupa Health, ButcherBox, and Athletic Greens. Our thoughts have a profound physiological effect on the body and can either help or hinder the healing process. Even just thinking about a negative experience can set off a cascade of physiological events in the body just as if it’s happening right now—the mind-body connection is truly that powerful. In today’s episode, I talk with Dr. Joe Dispenza, Emily Fletcher, and Dr. Leonard Calabrese about why our thoughts influence our physiology and what we can do to improve our health, even when we feel we are stuck. Once we are aware of our thoughts and learn to retrain our brains, using such techniques as meditation to break the conditioning process, we see substantial changes in health. Dr. Joe Dispenza’s passion can be found at the intersection of the latest findings from the fields of neuroscience, epigenetics, and quantum physics, where he explores the science behind spontaneous remissions. He uses that knowledge to teach people how to heal their bodies of health conditions, make significant changes in their lives, and evolve their consciousness. Since 2010, he has partnered with scientists and universities to perform extensive research on the effects that meditation has on the brain and body. He and his team have also studied gene expression, protein regulation, immune response, neurotransmitter changes, telomere length, and variations in bioactive cellular metabolic particles in novice and advanced meditators. Emily Fletcher is the founder of Ziva, the creator of the Ziva Technique, and regarded as a leading expert in meditation for high performers. She is also the author of Stress Less, Accomplish More: Meditation for Extraordinary Performance. Dr. Leonard Calabrese is a professor of medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and vice chair of the Department of Rheumatic and Immunologic Diseases. He is the director of the RJ Fasenmyer Center for Clinical Immunology at the Cleveland Clinic and holds joint appointments in the Department of Infectious Diseases and the Wellness Institute. He has received numerous awards and honors for his contributions to the advancements of immunology and wellness. This episode is brought to you by Rupa Health, ButcherBox, and Athletic Greens. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. For a limited time, new subscribers to ButcherBox will receive ground beef FOR LIFE. When you sign up today, ButcherBox will send you 2 lbs of 100% grass-fed, grass-finished beef free in every box for the life of your subscription. To receive this offer, go to ButcherBox.com/farmacy. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman.

This episode is brought to you by Rupa Health, BiOptimizers, and Vuori. Food and racism are heavily tied, and the history of fast food franchises in America is one of many examples. In order to continue the fight for civil rights and name ongoing social and racial disparities, it’s important to learn how we got here. I’m excited to dig into all this with Marcia Chatelain. Marcia Chatelain is a Professor of History and African American Studies at Georgetown University. The author of South Side Girls: Growing up in the Great Migration, she teaches about women’s and girls’ history, as well as black capitalism. Her latest book, Franchise: The Golden Arches in Black America examines the intricate relationship among African American politicians, civil rights organizations, communities, and the fast food industry. In 2021, Marcia received the Pulitzer Prize in History, the Hagley Prize in Business History, and the Organization of American Historians Lawrence W. Levine Award for Franchise. Marcia has received awards and honors from the Ford Foundation, the American Association of University Women, and the German Marshall Fund of the United States. In 2016, the Chronicle of Higher Education named her a Top Influencer in academia in recognition of her social media campaign #FergusonSyllabus, which implored educators to facilitate discussions about the crisis in Ferguson, Missouri in 2014. This episode is brought to you by Rupa Health, BiOptimizers, and Vuori. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. Check out a free, live demo with Q&A or create an account here. BiOptimizers Magnesium Breakthrough formula contains 7 different forms of magnesium. There is truly nothing like it on the market. Use the code hyman10 at checkout for 10% off your next order here. It’s the perfect time to upgrade your wardrobe! Vuori is offering my community 20% off your first purchase here. Here are more details from our interview (audio version / Apple Subscriber version): The history of African American owned fast food franchises (6:01 / 3:00) African American food culture, access, health, and economics (11:24 / 6:30) The food industry targets marginalized communities toward junk food consumption (16:44 / 9:30) Making the healthy choice the easy choice (18:19 / 15:20) Social determinants of health and necessary policy change (24:55 / 20:50) The true cost of the food we eat (34:22 / 29:00) The dark side of corporate social responsibility spending (36:49 / 31:25) Overcoming the power of corporate lobbying (39:07 / 33:46) Food sovereignty and traditional foods (47:16 / 41:30) Improving societal systems and institutions (54:37 / 49:20) Learn more about Marcia Chatelain here and get a copy of her book, Franchise: The Golden Arches in Black America, here.

This episode is brought to you by Athletic Greens and Eight Sleep. An astonishing seventy percent of cancer is diet-related. When it comes to treating cancer, conventional medicine is good at cutting it, burning it, and poisoning it, but many doctors fail to treat the root cause. Functional Medicine empowers patients and practitioners to optimize health by addressing the root causes of disease. In this episode of my new Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about the cancer epidemic, including the biggest cancer risks. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30+ million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Athletic Greens and Eight Sleep. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 free travel packs with your first purchase here. Eight Sleep’s Pod Pro mattress is so smart that it adjusts your temperature and also gives you individualized recommendations on how to sleep better the next night. Save $150 at checkout and get yours here. In this episode, we discuss (audio version / Apple Subscriber version): Five things we can do to reduce our cancer risk (4:08 / 00:56) The link between sugar and cancer (10:39 / 6:44) Emerging diagnostic tests and treatment options (12:56 / 9:24) My approach to handling a cancer diagnosis (15:35 / 12:10) Case study of a prostate cancer patient (18:10 / 14:56) Questions from our community on reducing risk, cancer education resources, foods to fight cancer, and more (24:20 / 19:25) Recap of how to reduce your cancer risk (32:06 / 27:34) Mentioned in this episode: Environmental Working Group Dr. Ralph Moss (Cancer Decisions) The Cancer Code Eat to Beat Disease Anticancer: A New Way of Life The Longevity Diet

This episode is brought to you by Athletic Greens, Paleovalley, and Rupa Health. Sugar lights up the addiction center in our brains, just like heroin and cocaine. Yet many of us consume more sugar than we are aware of because it’s lurking in so many foods that we would never expect. The average person consumes 152 pounds of it per year! Sugar is not just responsible for an increased waistline but also impacts our metabolic health, immune systems, mental health, and more. In today’s episode, I talk with Keegan Allen and Tom Hopper, Dr. Shebani Sethi Dalai, and Dr. Casey Means about why sugar addiction is so detrimental to our health and what we can do about it. Keegan Allen is an American actor, musician, photographer, and author. He’s known for his main role as Toby Cavanaugh on the Freeform series Pretty Little Liars. Allen’s passion in his younger years tended towards photography, cinematography, and other roles behind the camera. Tom Hopper is an English actor. He has appeared as Sir Percival in Merlin, Billy Bones in Black Sails, Dickon Tarly in Game of Thrones, and Luther Hargreeves in Netflix’s new show The Umbrella Academy. Dr. Shebani Sethi Dalai is a double board-certified physician in Obesity Medicine and Psychiatry. She is the Founding Director of Stanford University’s Metabolic Psychiatry program and Silicon Valley Metabolic Psychiatry, a new center in the San Francisco Bay Area focused on optimizing brain health by integrating low carb nutrition, comprehensive psychiatric care, and treatment of obesity with associated metabolic disease. Dr. Casey Means is a Stanford-trained physician, Chief Medical Officer and Co-founder of metabolic health company Levels, an Associate Editor of the International Journal of Disease Reversal and Prevention, and a Guest Lecturer at Stanford University. Dr. Means’ perspective has been recently featured in the New York Times, Wall Street Journal, Men's Health, Forbes, Business Insider, Techcrunch, Entrepreneur Magazine, Metabolism, Endocrine Today, and more. This episode is brought to you by Athletic Greens, Paleovalley, and Rupa Health. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. You can check out a free live demo with a Q&A or create an account at RupaHealth.com.

This episode is brought to you by Rupa Health, Thrive Market, and InsideTracker. What if you had a tool that helped you not only make better health decisions but also gave you real-time feedback on how your body uniquely reacts to any kind of food? Thanks to continuous glucose monitors this is something we’ll all be able to take advantage of in the near future. Levels is one company that’s been spearheading the field of wearable technology, providing an incredible amount of information on blood sugar responses and metabolic individuality. I talk to Dr. Casey Means about what we can learn from the 51 million data points Levels has already gathered on blood glucose reactions. Dr. Casey Means is a Stanford-trained physician, Chief Medical Officer and Co-founder of metabolic health company Levels, an Associate Editor of the International Journal of Disease Reversal and Prevention, and a Guest Lecturer at Stanford University. Dr. Means’ perspective has been recently featured in the New York Times, Wall Street Journal, Men's Health, Forbes, Business Insider, Techcrunch, Entrepreneur Magazine, Metabolism, Endocrine Today, and more. This episode is brought to you by Rupa Health, Thrive Market, and InsideTracker. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. You can check out a free live demo with a Q&A or create an account at RupaHealth.com. Thrive Market is an online membership-based grocery store that makes eating well convenient and more affordable. Join today at thrivemarket.com/hyman to receive an extra 40% off your first order and a free gift. If you’re curious about getting your own health program dialed-in to your unique needs, check out InsideTracker. Right now they’re offering my listeners 25% off at insidetracker.com/drhyman. Here are more of the details from our interview (audio version / Apple Subscriber version): The leading driver of mortality in the Western world (5:52 / 3:46) The type of foods that are driving cardio and metabolic disease (8:38 / 5:03) Learnings from 51 million continuous glucose monitor readings (12:28 / 8:53) Foods commonly believed to be healthy that actually spike blood sugar (20:39 / 17:04) How various food combinations affect blood sugar (21:16 / 17:44) Walking after eating can lower glucose levels (23:32 / 20:00) Foods we should never eat and surprising foods that spike glucose levels (27:27 / 22:07) Foods that don’t spike blood sugar but should still be avoided (44:22/ 38:52) How food combinations, sequencing, and when we eat influence glucose levels (51:33 / 46:03) What are normal and optimal blood sugar levels? (1:06:34 / 1:01:01) Learn more about Dr. Means’ work at https://www.levelshealth.com/. Levels is currently running a closed beta program. To skip the line and participate in their early access program today, visit levels.link/HYMAN.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on thyroid and Hashimotos with Dr. Natasha Fallahi. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health and Athletic Greens. Sleep is medicine, just like food is medicine, and may even be more important than diet. Sleep regulates your brain function, helps stabilize your mood, and is a time when the body heals. It’s absolutely critical for a healthy body. Sadly, over 70 million Americans don’t sleep well. This lack of sleep is degrading our health. We feel it in our energy level, it’s hard to focus, and it can even contribute to chronic illness. In this episode of my new Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, all about sleep and why it’s essential for a healthy body. We discuss why sleep is so important, how we can get better sleep including tips to create your own sleep ritual, and answer a variety of questions from our community. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30+ million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. You can check out a free live demo with a Q&A or create an account at RupaHealth.com. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. In this episode, we discuss (audio version / Apple Subscriber version): The importance of sleep (3:54 / 1:00) Three things that can improve quality of sleep (6:27 / 3:34) The risks of chronic sleep deprivation (10:31 / 7:34) Ideal hours of sleep (11:36 / 8:46) Conventional versus Functional Medicine approach to sleep problems (16:28 / 13:26) Case studies (19:34 / 16:40) Creating a sleep ritual before bed (22:25 / 19:26) My morning routine to ensure good sleep (24:24 / 21:26) Questions from our community including circadian rhythm, frequent wake ups, sleep trackers, and more (25:23 / 22:20) Mentioned in this episode: Sweet Dreams: How to Sleep Better, Lose Weight, and Live Longer Lights Out Dr. Hyman’s Sleep Master Class

This episode is brought to you by Rupa Health, Athletic Greens, and Eight Sleep. Aging doesn’t have to be a one-way street. Our diet and lifestyle patterns are fundamental to the quality of our health, and the way we age. In this episode, my guests and I explain how to support our health to help us live longer, and more vibrantly. Dr. David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study longevity, aging, and how to slow its effects. Their focus is on studying sirtuins as well as metabolism, neurodegeneration, cancer, cellular reprogramming, and more. Mark Sisson is the founder of the popular daily health blog, Mark’s Daily Apple, godfather to the Primal food and lifestyle movement, and New York Times bestselling author of The Keto Reset Diet and The Primal Blueprint. Mark launched Primal Kitchen, a real-food company that creates Primal/Paleo, keto, and Whole30-friendly kitchen staples. Dr. Gerald Lemole is a board-certified cardiothoracic surgeon and integrative physician. In 1968, he was a member of the surgical team that performed the first successful heart transplant in the United States. His books include After Cancer Care, The Healing Diet, An Integrative Approach to Cardiac Care, Facing Facial Pain, and Lymph & Longevity: The Untapped Secret to Health. Dr. Mehmet Oz has won ten Daytime Emmy® Awards for The Dr. Oz Show and is an Attending Physician at NY Presbyterian-Columbia Medical Center. Dr. Oz received his undergraduate degree from Harvard University and obtained a joint MD and MBA from the University of Pennsylvania School of Medicine and Wharton Business School. Dr. Oz is the proud author of eight New York Times bestsellers including his most recent, Food Can Fix It. Dr. Cindy Geyer received her bachelor of science and her doctor of medicine degrees, with honors, from the Ohio State University. She completed residency in internal medicine at Strong Memorial Hospital in Rochester, N.Y. and is triple board certified in internal medicine, integrative medicine and lifestyle medicine. Dr. Richard Isaacson serves as Director of the Center for Brain Health and Director of the Alzheimer’s Prevention Clinic (APC) at Florida Atlantic University’s Schmidt College of Medicine. He previously served as Director of the APC at the Weill Cornell Memory Disorders Program, Assistant Dean of Faculty Development, and Associate Professor of Neurology at Weill Cornell Medicine & NewYork-Presbyterian. This episode is brought to you by Rupa Health, Athletic Greens, and Eight Sleep. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs. You can check out a free live demo with a Q&A or create an account here. Right now when you purchase AG1 from Athletic Greens, you will receive 10 free travel packs with your first purchase here. Eight Sleep’s Pod Pro mattress is so smart that it adjusts your temperature and also gives you individualized recommendations on how to sleep better the next night. Save $150 at checkout and get yours here.

This episode is brought to you by Rupa Health, Eight Sleep, and ButcherBox. You might have heard the word “epigenetics” and wondered what the heck it means. Well to sum it up shorthand, epigenetics is how everything you’re exposed to throughout your life—your environment, your social relationships, your diet, etc.—impacts how your genes are expressed. Think of it like this: genes are our hardware and epigenetics are like software. Our software is something that can be changed and upgraded, it doesn’t have to be static. If you want to learn more about understanding, demystifying, and harnessing epigenetics, then this is the podcast episode for you. Today’s guest on The Doctor’s Farmacy is my good friend and mentor, Dr. Jeffrey Bland. We talk all about epigenetics and unpack what can be a complicated topic in terms you can actually understand. Dr. Bland’s career in health spans more than 40 years. A lifelong educator, Jeff has traveled the world many times over in his role as the “father of Functional Medicine.” In 1991, he and his wife, Susan, founded The Institute for Functional Medicine. In 2012, Jeff founded another educational nonprofit called the Personalized Lifestyle Medicine Institute. He is the author of The Disease Delusion: Conquering the Causes of Chronic Illness for a Healthier, Longer, and Happier Life, as well as countless additional books and research papers. This episode is brought to you by Rupa Health, Eight Sleep, and ButcherBox. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. You can check out a free live demo with a Q&A or create an account here. Eight Sleep’s Pod Pro mattress is so smart that it adjusts your temperature and also gives you individualized recommendations on how to sleep better the next night. Save $150 at checkout and get yours here. When you sign up today, ButcherBox will send you 2 lbs of 100% grass-fed, grass-finished beef free in every box for the life of your subscription. Just click here. Here are more of the details from our interview (audio version / Apple Subscriber version): The paradigm shift away from siloed medicine towards systems biology (7:42 / 4:26) New understandings about how our genes can be modified to reverse disease and aging (10:02 / 7:24) Early research that led to our understanding of how epigenetics works (12:02 / 10:00) Genes that can be imprinted and modified even into adulthood (19:27 / 16:02) Reversing our biological age (21:35 / 18:18) The influence of our external environment and experiences over our genes (27:03 / 24:10) How what we eat, how we love, how much stress we’re under, and more impacts our genes, our health, and the process of aging (35:08 / 30:32) The amazing benefits of phytochemicals in plants for human health (38:38 / 34:29) Trauma, PTSD, and our genes (51:05 / 45:45) Our ability to control the operating system of our biology (56:13 / 48:17) Learn more about Dr. Bland’s work with Big Bold Health here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health and Mitopure. The average American consumes 133 pounds of flour per year. Let that sink in. What we may not realize is that every time we eat white flour, we are harming ourselves. The starch in common wheat, typically known as modern dwarf wheat, raises your blood sugar more than table sugar! Eating a diet high in carbohydrates may affect not just your waistline, but also your brain function, energy, immune system, healthspan, and more. In this episode of my new Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about how and why to consider giving up bread for 30 days. We discuss why our modern wheat is not a good food choice on a daily basis, how to pause on eating bread for a month or more, why certain kinds of bread may be a better choice than others, questions from our community, and so much more. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30+ million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and Mitopure. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. You can check out a free live demo with a Q&A or create an account at RupaHealth.com. Mitopure is the first and only clinically tested pure form of a natural gut metabolite called Urolithin A that clears damaged mitochondria away from our cells and supports the growth of new healthy mitochondria. Get 10% off at timelinenutrition.com/drhyman and use code DRHYMAN10. In this episode, we discuss (audio version / Apple Subscriber version): Three reasons to stop eating bread for 30 days (1:04 / 00:54) Bread’s effect on insulin and blood sugar (5:40 / 5:28) Can bread and/or flour cause leaky gut? (10:13 / 7:50) What to expect when stopping bread for 30 days (13:55 / 13:31) Different kinds of bread and how they impact the body (16:13 / 16:05) Case study of a woman with multiple conditions who healed on an elimination diet (20:27 / 20:18) Questions from our community including eating gluten in other countries, Roundup in wheat, hunger when not eating carbs, and more (23:29 / 23:22) What kinds of bread I eat (28:35 / 28:26) Steps to take now to go bread-free (33:24 / 33:13) Mentioned in this episode: Lynn’s Life Breads

This episode is brought to you by Rupa Health, Athletic Greens, and Eight Sleep. Feeling tired during the day may not just be due to a poor night’s sleep. Most of us can relate to feeling run-down and tired, even when we’re getting enough sleep. There are many reasons why your body might not be functioning well during the day. In this compilation episode, I talk to Dr. Steven Gundry and Dr. Elizabeth Boham about the many factors that can impact energy production such as diet, circadian rhythm, movement, gut health, and more. We also get into dietary recommendations, fixing nutritional deficiencies and hormonal imbalances, and much more. Dr. Steven Gundry is one of the world’s top cardiothoracic surgeons and a pioneer in nutrition, as well as medical director at The International Heart and Lung Institute Center for Restorative Medicine. He has spent the last two decades studying the microbiome and now helps patients use diet and nutrition as a key form of treatment. He is author of many New York Times bestselling books including The Plant Paradox, and The Plant Paradox Cookbook, and The Longevity Paradox: How to Die Young at a Ripe Old Age, and just released The Energy Paradox: What to Do When Your Get-Up-and-Go Has Got Up and Gone. He also is the founder of GundryMD, a line of wellness products and supplements, and host of The Dr. Gundry Podcast. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women’s Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. This episode is brought to you by Rupa Health, Athletic Greens, and Eight Sleep. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. You can check out a free live demo with a Q&A or create an account at RupaHealth.com. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Eight Sleep’s Pod Pro mattress is so smart that it adjusts your temperature and also gives you individualized recommendations on how to sleep better the next night. To get yours, go to eightsleep.com/mark to check out the Pod Pro mattress or mattress cover and save $150 at checkout.

This episode is brought to you by Rupa Health, BiOptimizers, and Thrive Market. What if I told you it was possible to reverse your age by three years, in just eight weeks? Well, it is, and today you can learn how. Perhaps the greatest part of this exciting news is that the changes we can make to reverse biological aging are pretty simple and very accessible. The amazing doctor behind this groundbreaking research is my good friend, colleague, and long-time collaborator Dr. Kara Fitzgerald. Dr. Fitzgerald is on the faculty of the Institute for Functional Medicine, is an IFM Certified Practitioner, and lectures globally on Functional Medicine. She runs a Functional Medicine Clinic Immersion program for professionals and hosts a podcast series, New Frontiers in Functional Medicine, and an active blog on her website. Her clinical practice is in Sandy Hook, Connecticut. With the Helfgott Research Institute, Dr. Fitzgerald is actively engaged in clinical research on the DNA methylome using a diet and lifestyle intervention developed in her practice. The first publication from the study focuses on the reversal of biological aging and was published this past April in the journal Aging. Her new book, Younger You, as well as her 3 Years Younger Program, have just been released. This episode is brought to you by Rupa Health, BiOptimizers, and Thrive Market. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs. You can check out a free live demo with a Q&A or create an account here. Bioptimizers Magnesium Breakthrough formula contains 7 different forms which all have different functions in the body. For 10% off, use code HYMAN10 at checkout here. Join Thrive Market today to receive an extra 40% off your first order and a free gift here. Here are more of the details from our interview (audio version / Apple Subscriber version): Reversing your biological age through epigenetics (6:36 / 3:08) Initial scientific studies that have shown biological age reversal (9:22 / 5:25) Dr. Fitzgerald’s 8-week age reversal study design (11:14 / 7:46) Seminal research around influencing and regulating gene expression through nutritional interventions (25:41 / 20:39) Using food as medicine (30:35 / 27:19) How exercise, sleep, and meditation were factored into Dr. Fitzgerald’s study (40:40 / 35:16) Primary findings from Dr. Fitzgerald’s research (47:12 / 41:57) Practical ways to reverse your biological age (1:01:43 / 56:32) Influencing gene expression before conception and during pregnancy and infancy (1:04:29 / 59:48) Aging without declining in health (1:08:06 / 1:04:25) Get a copy of Dr. Fitzgerald's book Younger You: Reverse Your Bio Age―and Live Longer here. Learn more about Dr. Kara Fitzgerald at www.drkarafitzgerald.com and take her Biological Age Self-Assessment here.

This episode is brought to you by Rupa Health and Paleovalley. Protecting your brain and cognitive function is not just for the elderly. It’s never too early to start protecting your brain, which is something we should all think more about as Alzheimer’s and dementia rates continue to rise. We can start with healthy lifestyle choices that affect diet, sleep, stress management, and more. The bonus of brain-healthy lifestyle choices like these is that they protect the health of your entire body as well. In this episode of my new Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about Alzheimer’s and dementia. We talk about early detection, contributors to cognitive dysfunction, foods that fuel the brain, and so much more. We also discuss how other factors, such as toxicity, sleep apnea, and even lack of community, affect brain health. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30+ million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and Paleovalley. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. You can check out a free live demo with a Q&A or create an account at RupaHealth.com. Right now, Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. In this episode, we discuss (audio version / Apple Subscriber version): Things to do in your 20s, 30s, and 40s to reduce your risk of cognitive decline (4:23 / 1:15) Using brain scans to detect Alzheimer’s and dementia (10:37 / 7:26) Contributors to cognitive dysfunction (13:30 / 10:00) Fueling your brain with a healthy diet (18:16 / 15:07) The importance of movement to reduce your risk of cognitive decline (28:34 / 25:10) Ineffective pharmaceutical interventions for Alzheimer’s (31:51 / 28:08) Why sleep apnea increases your risk of cognitive decline (38:24 / 34:48) The effects of chronic toxicity on the brain (49:34 / 46:14) 5 things everyone can do to improve brain health (54:01 / 50:24) Significant signs of cognitive decline (1:05:57 / 1:02:49)

This episode is brought to you by Rupa Health, Athletic Greens, and InsideTracker. Wellness is more than just eating right and exercising; it’s also much more than just feeling “okay.” Feeling well means feeling whole, balanced, vibrant, and alive. And there are many moving pieces that we can tap into to feel empowered in our own wellness journey. Functional Medicine looks at the body with a systems-based approach, understanding how all our different parts work together and looking at a symptom as a sign of dysfunction that we need to get to the root cause of, not just tame. I sat down with Dr. Elizabeth Boham to discuss what it means to get to the root cause of disease and how the principles we practice do exactly that. We talk about the many different parts of healing the whole body, like enhancing detoxification pathways, correcting nutrient deficiencies, supporting the microbiome, and so much more. Dr. Boham is a physician and nutritionist who practices Functional Medicine as part of my team at The UltraWellness Center in Lenox, MA. Through her practice and lecturing, she has helped thousands of people achieve their wellness goals. She is part of the faculty of the Institute for Functional Medicine and has been featured on the Dr. Oz show and in a variety of publications and media including Huffington Post, The Chalkboard Magazine, and Experience Life. Her DVD Breast Wellness: Tools to Prevent and Heal from Breast Cancer explores the Functional Medicine approach to keeping your breasts and whole body well, a topic she is passionate about as a breast cancer survivor. This episode is brought to you by Rupa Health, Athletic Greens, and InsideTracker. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. You can check out a free live demo with a Q&A or create an account at RupaHealth.com. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 free travel packs with your first purchase. All you have to do is visit athleticgreens.com/hyman. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 25% off at insidetracker.com/drhyman.

This episode is brought to you by Eight Sleep, Athletic Greens, and Mitopure. I recently spent time in Sardinia, Italy, which is known for having one of the world’s longest-lived populations. It simply blew me away. After getting to know the people, their day-to-day activities, their diets, and their sense of community I can totally see why they live such long and happy lives. So, how can we embrace these same aspects of Sardinian life in our own busy Western world? Blue Zones pioneer Dan Buettner joins me on this episode to talk about that and so much more. Dan Buettner is an explorer, National Geographic Fellow, award-winning journalist and producer, and New York Times bestselling author. He discovered the five places in the world— dubbed Blue Zones hotspots—where people live the longest, healthiest lives. Dan now works in partnership with municipal governments, large employers, and health insurance companies to implement Blue Zones Projects in communities, workplaces, and universities. Blue Zones Projects are well-being initiatives that apply lessons from the Blue Zones to entire communities by focusing on changes to the local environment, public policy, and social networks. The program has dramatically improved the health of more than 5 million Americans to date. His new book, The Blue Zones Challenge: A 4-Week Plan for a Longer Better Life is a four-week guide and year-long sustainability program to jump-start your longevity journey. This episode is brought to you by Eight Sleep, Athletic Greens, and Mitopure. Head over to eightsleep.com/mark to check out the Pod Pro and save $150 at checkout. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase athleticgreens.com/hyman. Timeline Nutrition is offering my community 10% off MitoPure, which you can get in a capsule, powder, or protein blend, at timelinenutrition.com/drhyman. Here are more of the details from our interview (audio version / Apple Subscriber version): Challenging our preconceived notions of aging (6:49 / 3:38) 9 lifestyle habits of the world’s healthiest, longest-lived people (10:32 / 7:24) How our built environment influences our health (17:31 / 14:23) Teachings on happiness from the Blue Zones (26:30 / 21:39) Community, relationships, loneliness, and longevity (29:17 / 25:56) What’s driving our decreasing life expectancy? (40:34 / 36:20) Obesity rates in neighborhoods that allow billboard advertising and other environmental influences on health (45:49 / 40:53) Foods to never have in your kitchen, and foods to always have on hand (54:06 / 49:16) Is bread healthy, and if so, what kind? (58:32 / 53:50) Get a copy of Dan’s book The Blue Zones Challenge: A 4-Week Plan for a Longer Better Life here. Learn more about Dan’s work at https://www.bluezones.com/.

This episode is brought to you by Rupa Health and ButcherBox. Fasting is a great way to optimize your health, and it’s more approachable than you might think. It is a free tool that activates all the systems in your body to protect you, heal you, and help you live longer. Fasting can help to reduce inflammation, brain fog, and insulin resistance. It can also increase energy and bone density and activate autophagy, which is the process of cleaning out damaged cells. In this episode of my new Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about the many benefits of fasting. We also talk about the different types of fasting so you can determine if one is right for you. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, Dhru Purohit Podcast, is a top 50 global health podcast with over 30+ million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and ButcherBox. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. You can check out a free live demo with a Q&A or create an account at RupaHealth.com. Right now, when you sign up to Butcher Box today, you’ll get 2 lbs of wild-caught Alaskan salmon free in your first box plus $10 off by going to butcherbox.com/farmacy. In this episode, we discuss (audio version / Apple Subscriber version): The top benefits of fasting (4:07 / 1:08) Zombie cells and their effect on aging and inflammation (7:54 / 4:44) Four different types of fasting (11:46 / 8:44) My personal experiences with fasting (19:06 / 15:58) Fasting’s impact on sleep (24:12 / 21:08) Fasting for female bodies (27:38 / 24:31) Questions from our community on high blood pressure, getting adequate calories, fasting during pregnancy, and more (29:32 / 26:19) The impact of fasting on metabolism (43:26 / 40:35) The role of continuous glucose monitors in personalizing diet (53:25 / 50:20) Mentioned in this episode: Enhancing Your “Healthspan” to Live Well for 100+ Years with Dr. Peter Attia How to Use Intermittent Fasting to Lose Weight, Live Longer, and Feel Better with Dr. Jason Fung Is Cancer Caused by Sugar? with Dr. Jason Fung

This episode is sponsored by Thrive Market, Athletic Greens, and Rupa Health. The school of thought around cancer used to be focused only on the genetic component. But we now know that our environment—the air we breathe, the food we eat, even our relationships—has an enormous cellular impact on our ability to prevent and treat cancer. In this episode, my guests and I discuss the Functional Medicine approach to cancer, which empowers patients and practitioners to achieve the highest expression of health by working collaboratively to address the root causes of disease. Drew Ramsey is a psychiatrist, author, farmer, and founder of the Brain Food Clinic in New York City, offering treatment and consultation for depression, anxiety, and emotional wellness concerns. He is the author of multiple books, including the award-winning cookbook Eat Complete: The 21 Nutrients that Fuel Brain Power, Boost Weight Loss and Transform Your Health. Dr. Todd LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medicine, and is an Institute for Functional Medicine Certified Practitioner. He has been practicing Functional Medicine for over 15 years focusing on Optimal Aging, Bio-Detoxification, Gastrointestinal Health, Systemic Inflammation, Autoimmune disorders and the Neurobiology of mood and cognitive disorders. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including women’s health and breast cancer prevention, insulin resistance, heart health, weight control and allergies. Peter Attia is the founder of Attia Medical, PC, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity. His approach focuses on increasing lifespan by delaying the onset of chronic disease, while simultaneously improving “healthspan,” or quality of life. Tom Hopper is an English actor. He has appeared as Sir Percival in Merlin, Billy Bones in Black Sails, Dickon Tarly in Game of Thrones, and Luther Hargreeves in Netflix’s new show The Umbrella Academy. Keegan Allen is an American actor, musician, photographer, and author. He’s known for his main role as Toby Cavanaugh on the Freeform series Pretty Little Liars. Allen’s passion in his younger years tended towards photography, cinematography, and other roles behind the camera. This episode is brought to you by Thrive Market, Athletic Greens, and Rupa Health. When you join Thrive Market today, you can get an extra 40% off your first order and a free gift by going to thrivemarket.com/hyman. Right now, Athletic Greens is offering my community 10 free travel packs of AG1 with your first purchase at athleticgreens.com/hyman. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on the role of brain inflammation in chronic fatigue and depression with Dr. Datis Kharrazian. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is sponsored by Rupa Health, BiOptimizers, and HigherDOSE. We’re up against an epidemic of chronic metabolic diseases. One thing they all have in common is a component of insulin dysregulation. Take that into account with the fact that 90% of people who have insulin resistance are going to the doctor and remaining undiagnosed. Why then, are we testing everything but insulin? Today, I take a deep dive into the topic of insulin resistance and metabolic health with Dr. Ben Bikman. Dr. Bikman is a renowned metabolic research scientist and a popular speaker on human metabolism and nutrition. Backed by years of research, Dr. Bikman’s mission is to help the world appreciate the prevalence and relevance of insulin resistance. He is the author of the book, Why We Get Sick, which offers a thought-provoking yet real solution to insulin resistance and reversing pre-diabetes, improving brain function, shedding fat, and preventing diabetes. Dr. Bikman has a Doctor of Philosophy in Bioenergetics from East Carolina University, and completed a postdoctoral fellowship in metabolic disorders with the Duke-National University of Singapore Medical School. This episode is brought to you by Rupa Health, BiOptimizers, and HigherDOSE. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here. Right now, you can try Bioptimizers Magnesium Breakthrough for 10% off at magbreakthrough.com/hyman and use code hyman10 at checkout. Get your own Infrared Sauna Blanket or Infrared PEMF Mat and save 15% at HigherDOSE.com/hyman or use the code FARMACY15 at checkout. Here are more of the details from our interview (audio version / Apple Subscriber version): The common driver of metabolic syndrome and chronic disease (5:10 / 1:30) What is insulin resistance and why is it so underdiagnosed? (7:57 / 5:08) How insulin resistance affects the liver, sex hormones, weight gain, aging, and the brain (15:36 / 12:45) Differences in how high-carb and low-carb diets affect metabolism (30:11 / 24:55) Three primary causes of insulin resistance (47:52 / 42:39) Fat, saturated fats, and insulin resistance (50:58 / 45:46) How to know if insulin resistance is a problem for you (1:02:32 / 56:50) Ethnic disparities in metabolic predisposition (1:09:18 / 57:11) Top things you can do to prevent and reverse the effects of insulin resistance (1:13:07 / 1:03:54) Insulin’s role in mTOR, a regulator of aging (1:31:17 / 1:26:05) Get a copy of Dr. Bikman’s book, Why We Get Sick here and check out his new company HLTH Code here. Mentioned in this episode: How To Work With Your Doctor To Get What You Need

This episode is brought to you by Rupa Health and Paleovalley. We’ve been told over and over again that dairy is a great source of calcium; that milk makes healthy bones and we should drink it daily. I’m here to tell you that this is not true. Cow’s milk from conventionally raised cattle contains dozens of reproductive hormones, allergenic proteins, antibiotics, chemicals, inflammatory compounds, and growth factors, some of which are known to promote cancer. While humans are the only species that continue to drink milk after weaning, we have no biological requirement for this food. Moreover, the milk we drink today is not what our grandparents drank. In this episode of my new Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about why we should avoid almost all dairy. We also discuss some of the popular myths about dairy, the types of dairy that are okay to eat, and much more. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, Dhru Purohit Podcast, is a top 50 global health podcast with over 30+ million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and Paleovalley. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here. Paleovalley is offering 15% off your entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. In this episode, we discuss (audio version / Apple Subscriber version): The dangers of industrial dairy (3:55 / 1:00) Why Functional Medicine practitioners include dairy in the elimination diet (12:05 / 9:09) Why I cut out most dairy from my diet (14:53 / 11:57) Milk isn’t a necessary source of calcium or vitamin D (17:46 / 14:48) The types of dairy I will eat (22:00 / 19:04) Is raw milk safe? (23:29 / 20:34) Giving up dairy: patient success stories (25:26 / 22:31) Why the combination of dairy and sugar is particularly harmful (27:41 / 24:51) Considerations for selecting dairy alternatives (30:22 / 27:26) How to minimize the effects of lactose, casein, and hormones in dairy (34:19 / 31:14) Mentioned in this episode Milk and Health Is Butter Back? A Systematic Review and Meta-Analysis of Butter Consumption and Risk of Cardiovascular Disease, Diabetes, and Total Mortality The Elimination Diet

This episode is sponsored by Rupa Health and Athletic Greens. We’ve all been there—changing an old habit or creating a new one can be challenging. But when we use science to understand the secrets to lasting behavior change, it’s clear there are ways to overcome the struggle and get the results we want. Today, I talk to Dr. BJ Fogg about the science of lasting behavior change and the success he’s seen in those who’ve used his system. Dr. Fogg is a behavior scientist with deep experience in innovation and teaching. For the past 20 years at Stanford University, he has directed a research lab and he also teaches his models and methods in graduate seminars. His New York Times bestselling book, Tiny Habits: The Small Changes that Change Everything, was published in early 2020 and is contracted to be published in over 25 languages. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here. Athletic Greens is offering my listeners 10 free travel packs of AG1 when you make your first purchase here. Here are more of the details from our interview (audio version / Apple Subscriber version): How BJ’s Mormon upbringing, homosexuality, and perfectionism set the groundwork for his work on behavior change (7:35 / 4:07) Why feeling successful is the key to building new habits and behavior change (16:06 / 12:19) The Fogg Behavior Model and the convergence of motivation, ability, and prompt (17:25 / 14:19) Why specificity and simplicity are key to behavior change (22:43 / 19:05) The pervasive myth that eating less and exercise more is the secret to weight loss (24:54 / 21:27) Why behavior change is not about discipline and willpower (26:27 / 23:36) Repetition does not create habits, emotion does (32:53 / 29:42) Three ways to make lasting change (45:02 / 41:49) Two overarching maxims for creating behavior change—help people do what they already want to do and help people feel successful (50:52 / 47:29 Untangling vs. breaking habits (56:54 / 52:08) Learn more about BJ’s work at tinyhabits.com and follow him on Facebook @TinyHabits, on Instagram @bjfogg, and on Twitter @bjfogg. Join the Free 5-Day Program to Build Habits at https://www.tinyhabits.com/join and learn more about the Tiny Habits Certification Program at https://www.tinyhabits.com/certify.

Modern love comes with an unprecedented list of expectations. Relationships can of course be a source of amazing connection and joy, but they can also be really hard. We want our partner to be our best friend, lover, confidant, coworker, therapist, and so much more. We want from one person what an entire village used to provide. To take it a step further, we want a soul mate; we want in another human what we used to look for in the realm of the divine. We want that person to help us become the best version of ourselves. I’ve been extremely lucky in my life with my career and friendships, but romantic relationships haven’t come easy for me. I was thrilled to take a deeper look at this part of my life in this episode with my dear friend Esther Perel. Psychotherapist and New York Times bestselling author Esther Perel is recognized as one of today’s most insightful and original voices on modern relationships. Fluent in nine languages, she helms a therapy practice in New York City and serves as an organizational consultant for Fortune 500 companies around the world. Her celebrated TED Talks have garnered more than 30 million views and her bestselling books, Mating in Captivity and The State of Affairs, are global phenomena translated into nearly 30 languages. Esther is also an executive producer and host of the popular podcasts Where Should We Begin? and How’s Work? Her latest project is Where Should We Begin - A Game of Stories with Esther Perel. Here are more of the details from our interview: Our expectations of romantic relationships have drastically changed over time (4:08) Our childhood sets us up for difficulty in romantic relationships (7:08) Why we choose partners who activate our own specific issues (11:19) What drives couples to divorce and why the end of a relationship does not necessarily equate to failure (15:02) What brings couples to couples therapy today vs. in past decades (19:40) Four relationship killers (27:10) What makes a relationship successful? (28:32) The card game that Esther created during the pandemic to incorporate lightness and play into our relationships (35:06) How our relationship to giving and receiving impacts our relationships (45:55) Esther’s main nuggets of wisdom from her work with couples (54:24) Learn more about Esther Perel at https://www.estherperel.com/ and her new card game, Where Should We Begin - A Game of Stories at https://www.estherperel.com/where-should-we-begin-the-game. Follow Esther on Facebook @Esther.Perel, on Instagram @EstherPerelOfficial, and on Twitter @EstherPerel.

This episode is sponsored by Essentia, Thrive Market, and Rupa Health. If you stop to look at the real reasons you’re eating certain foods, it’s not a lack of self-control like the stigma suggests. It is a lack of other things in your life, though. Today on The Doctor’s Farmacy, Dr. Rangan Chatterjee and I break down the factors that contribute to overeating and eating nutrient-poor foods and look at the best methods for healthy and lasting weight loss. Dr. Chatterjee is regarded as one of the most influential medical doctors in the UK and wants to change how medicine will be practiced for years to come. He hosts the most listened to health podcast in the UK and Europe, Feel Better, Live More—which regularly tops the Apple Podcast charts and is listened to by over 2 million people every single month. This episode is brought to you by Essentia, Thrive Market, and Rupa Health. Essentia is having its last big sale of the year now. Get 25% off plus an additional exclusive $100 off with a purchase of a Queen, King, or California King mattress here. Thrive Market is offering all Doctor's Farmacy listeners an extra 25% off your first purchase and a free gift when you sign up for Thrive Market here. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. You can check out a free live demo with a Q&A or create an account here. Here are more of the details from our interview (audio version / Apple Subscriber version): A personalized and compassionate approach to weight loss (7:13 / 3:24) Why do we eat? (14:55 / 11:07) Eliminating blame and shame around weight gain and weight loss (18:50 / 15:00) Examining what we are hungry for (26:25 / 21:05) Making your environment and home a “safe zone” (33:16 / 28:24) Planning your nutritional week (40:25 / 35:03) The cost, time, and skills needed to cook for yourself (42:11 / 36:53) How close are you to feeling great? (54:31 / 49:55) The role of exercise in weight loss (58:06 / 52:46) The 3 daily habits that Dr. Chatterjee recommends (1:07:06 / 1:01:50) Learn more about Dr. Chatterjee at https://drchatterjee.com/ and get Dr. Chatterjee’s book, Feel Great, Lose Weight: Simple Habits for Lasting and Sustainable Weight Loss at https://drchatterjee.com/feel-great-lose-weight.

I was lucky enough to learn at a young age that we can write our own stories. We can become the authors of our own lives instead of the victims—living authentically is a cornerstone of that process. Throughout life we’re posed with obstacles, successes, and everything in between. My guest on today’s episode of The Doctor’s Farmacy, the one and only Matthew McConaughey, shares how challenging events (redlights) can provide us with the opportunity for growth and success (greenlights), which is the focus of his new book Greenlights. Academy Award–winning actor Matthew McConaughey is a husband, father of three children, and a loyal son and brother. He considers himself a storyteller by occupation, believes it’s okay to have a beer on the way to the temple, feels better with a day’s sweat on him, and is an aspiring orchestral conductor. In 2009, Matthew and his wife, Camila, founded the just keep livin Foundation, which helps at-risk high school students make healthier mind, body, and spirit choices. In 2019, McConaughey became a professor of practice at the University of Texas at Austin, as well as Minister of Culture/M.O.C. for the University of Texas and the City of Austin. McConaughey is also brand ambassador for Lincoln Motor Company, an owner of the Major League Soccer Club Austin FC, and co-creator of his favorite bourbon on the planet, Wild Turkey Longbranch. Here are more of the details from our interview: What Matthew found when he looked back on the journals he kept over 30 years (4:49) The science of satisfaction (8:01) Being an author vs. victim of your life (10:55) Reframing selfishness (13:05) Matthew’s recurring dream and what he did to follow it (17:39) The transformative wrestling match that Matthew inadvertently found himself participating in (23:55) Prioritizing what matters most to you (36:30) How relinquishing need can bring in more (42:32) The power of journaling and writing down your thoughts (43:28) Get a copy of Matthew’s book, Green Lights at https://greenlights.com/. Follow Matthew on Facebook @MatthewMcConaughey, on Instagram @officiallymcconaughey, and on Twitter @McConaughey.

This episode is sponsored by Rupa Health and ButcherBox. I’ve always been fascinated by the concept of human potential and the mind-body connection. Time and time again, I’ve seen that mindset is a defining factor in how successful my patients are on their healing journey. The mind-body connection is a powerful one, so much so that there are numerous reports of spontaneous remission of chronic pain and diseases when people change their headspace. Digging into our subconscious thoughts and beliefs and redefining how we see our future can have real, long-lasting impacts on our physical health. I was so excited to sit down with Dr. Joe Dispenza to talk about his work in mind-body medicine, helping people overcome their biggest obstacles and form new, healthy, limitless lives. Dr. Joe’s passion can be found at the intersection of the latest findings from the fields of neuroscience, epigenetics, and quantum physics to explore the science behind spontaneous remissions. He uses that knowledge to teach people how to heal their bodies of health conditions, make significant changes in their lives, and evolve their consciousness. This episode is brought to you by Rupa Health and ButcherBox. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here. This holiday, ButcherBox is proud to give new members 2 pounds of ground beef in your first box plus $10 off. To receive this offer, go to ButcherBox.com/farmacy. Here are more of the details from our interview (audio version / Apple Subscriber version): How Dr. Joe first became interested in studying spontaneous remissions (8:10 / 5:09) Changing your reality requires changing yourself (10:42 / 7:39) How your past can control your present and keep you unwell, and how to break free from it (14:08 / 11:07) Moving out of stress to an elevated state of bliss, love, and ecstasy (23:15 / 20:07) Rewiring your brain to break habitual thought and emotional patterns (28:44 / 25:18) The power of using mental rehearsal to create our present and future reality (32:49 / 27:36) The four necessary elements of healing your body with your mind (40:58 / 37:47) Why practicing gratitude is a gateway to improving our health and wellbeing (43:27 / 40:18) How our thoughts can change our gene expression (51:57 / 48:22) Remarkable stories of healing and spontaneous remissions (1:01:18 / 58:20) Learn more about Dr. Joe Dispenza, his online course, Dr. Joe Live, live events, and more at www.drjoedispenza.com and follow him on Facebook @DrJoeDispenzaOfficialNewsFanPage, on Instagram @drjoedispenza, and Twitter @drjoedispenza.

This episode is sponsored by Rupa Health and Athletic Greens. Millions of individuals worldwide are affected by autoimmune diseases including rheumatoid arthritis, lupus, multiple sclerosis, inflammatory bowel disease, type-1 diabetes, hypothyroidism, psoriasis, and many others. Simply put, autoimmune diseases are conditions where the body’s immune system attacks its own tissues rather than a foreign molecule like bacteria. This happens when something confuses the immune system. In this compilation episode, I talk to Dr. Cynthia Li, Dr. George Papanicolaou, Dr. Todd LePine, Dr. Steven Phillips, and Dana Parish about out-of-the-box ways to treat autoimmune disease. We also discuss the importance of healing your gut and optimizing your diet, treating hidden infections, and more. Dr. Cynthia Li received her medical degree from the University of Texas Southwestern Medical Center in Dallas. She currently has a private practice in Berkeley, CA and is the author of Brave New Medicine: A Doctor’s Unconventional Path to Healing Her Autoimmune Illness. Dr. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is Board Certified in Family Medicine from Abington Memorial Hospital. In 2015, he established Cornerstone Personal Health—a practice dedicated entirely to Functional Medicine. He joined The UltraWellness Center in 2017. Dr. Todd LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medicine. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. Dr. Steven Phillips is a renowned Yale-trained physician, international lecturer, and media go-to expert. Well-published in the medical literature, he has treated over 20,000 patients with complex, chronic illness from nearly 20 countries. Dr. Phillips experienced firsthand the nightmare of an undiagnosed, serious infection after nearly dying from his own mystery illness. He figured out how to save his own life when 25 doctors could not. Dana Parish developed Lyme-induced heart failure as a result of being improperly diagnosed by some of the “top” doctors in the country—and had her life saved by Dr. Steven Phillips. A chart-topping Sony/ATV singer/songwriter who has written songs for artists like Celine Dion and Idina Menzel, she has become a major voice in the world of chronic illness. Her popular column on Huffington Post has been read by more than one million people globally. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here. Athletic Greens is offering my listeners 10 free travel packs of AG1 when you make your first purchase here.

This episode is brought to you by BiOptimizers, Athletic Greens, and Rupa Health. What if I told you we’ll reach a point in time where scientific breakthroughs will extend our lives by more than a year, for every year we are alive? This is called longevity escape velocity, and some experts think it’s only 12 to 15 years away. Of course, getting to that point is multidimensional. It means addressing health from all angles, with personal lifestyle choices, technology, and more. On today’s episode, I’m excited to talk to Peter Diamandis about the future of longevity interventions and why we won’t always have the same idea of aging that we do today. Peter Diamandis is the founder and executive chairman of the XPRIZE Foundation, which leads the world in designing and operating large-scale incentive competitions. He was recently named by Fortune as one of the “World’s 50 Greatest Leaders.” He is also the executive founder of Singularity University, a graduate-level Silicon Valley institution that counsels the world's leaders on exponentially growing technologies. This episode is brought to you by BiOptimizers, Athletic Greens, and Rupa Health. Try BiOptimizers Magnesium Breakthrough for 10% off by going to magbreakthrough.com/hyman and using the code HYMAN10. Athletic Greens is offering my listeners 10 free travel packs of AG1 when you make your first purchase at athleticgreens.com/hyman. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. You can check out a free live demo with a Q&A or create an account at RupaHealth.com. Here are more of the details from our interview (audio version / Apple Subscriber version): What is longevity? (6:30 / 2:19) Our view of aging may really be one of abnormal aging (10:28 / 7:26) Why we age and why we don't have to (14:26 / 10:45) Scientific evidence of age reversal in animals (28:28 / 22:46) The fundamentals of improving health and living longer, better (31:25 / 26:09) Using diagnostics and early detection for longevity (40:11 / 32:57) Promising, out-of-the-box therapies on the horizon to enhance longevity (46:55 / 42:22) Metformin vs. diet and lifestyle for blood glucose level reversal (57:36 / 52:20) Total plasma exchange therapy (1:03:06 /1:00) How additional life expectancy of humanity will contribute to the global economy (1:10:15 / 1:05:18) Pre-order your copy of Lifeforce here and sign up for Peter's Longevity Insider here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content. Mentioned in this episode: How To Work With Your Doctor To Get What You Need

This episode is brought to you by Rupa Health and Paleovalley. While the term “superfood” carries a certain hype, some foods do earn that status. Food is medicine. And some foods are more powerful medicines than others! Food is the most powerful tool to create optimal health. In this episode of my new Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about the power of using food as medicine. I also share five superfoods I frequently enjoy that you should also incorporate into your eating plan. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, the Dhru Purohit Podcast, is a top 50 global health podcast with over 30+ million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and Paleovalley. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here. Paleovalley is offering 15% off your entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. In this episode, we discuss (audio version / Apple Subscriber version): Food is information that drives all of your body’s biochemistry (5:09 / 1:30) Superfood #1: konjac root (6:47 / 3:25) Superfood #2: Himalayan Tartary buckwheat (7:52 / 4:40) Superfood #3: cruciferous vegetables (10:08 / 6:47) Superfood #4: mushrooms (12:44 / 9:21) Superfood #5: green tea (14:04 / 10:39) Why the quality of what you eat matters (14:48 / 11:43) Feeding the 7 systems of the body (25:35 / 22:12) Janice’s story: a case study of using food as medicine (32:23 /29:00) What I eat every day and foods I’ll never eat (39:36 / 36:12) Mentioned in this episode: Chai Pancake Recipe Try This: A Deep Dive Into The Healing Power Of Polyphenols Shake Recipes *My Masterclass on dairy will air Jan. 2022

This episode is sponsored by Rupa Health and Athletic Greens. We are in an epidemic of chronic illness. Despite the advances in conventional medical care over the last decades, this system of medicine is governed by a persistent myth that if you know the name of your disease, you know what’s wrong with you. Once you have a label, you are put in the group of people who have the same label, and it is assumed you carry the attributes of this group. Unfortunately, this approach or method of thinking is outdated, increasingly useless, and often dangerous. Functional Medicine, on the other hand, looks at the body with a systems-based approach, understanding how all our different parts work together and looking at a symptom as a sign of dysfunction that we need to get to the root cause of, not just tame. In this compilation episode, I take you through eight things you can do to reset your body and reduce chronic illness. I also talk about the risks of a fatty liver, how inflammation impacts the body, and the importance of good sleep. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here. Athletic Greens is offering my listeners 10 free travel packs of AG1 when you make your first purchase here.

This episode is brought to you by Beekeeper’s Naturals, BiOptimizers, and Cozy Earth. Despite what the conventional medical model has taught us about cognitive decline and Alzheimer’s, these disorders are actually within our power to stop, slow, and reverse. There’s no better person to talk to about reducing the risk of cognitive deficits and supporting optimal brain health than today’s guest on The Doctor’s Farmacy, Dale Bredesen. Dr. Bredesen is internationally recognized as an expert in the mechanisms of neurodegenerative diseases such as Alzheimer's disease, and the author of the New York Times bestsellers The End of Alzheimer's, The End of Alzheimer's Program, and his latest book The First Survivors of Alzheimer's: How Patients Recovered Life and Hope in Their Own Words. He has held faculty positions at UC San Francisco, UCLA, and the University of California San Diego. He has directed the Program on Aging at the Burnham Institute before coming to the Buck Institute for Research on Aging in 1998 as its founding president and CEO. He is currently a professor at UCLA. This episode is brought to you by Beekeeper’s Naturals, BiOptimizers, and Cozy Earth. Beekeeper’s Naturals is giving my community an exclusive offer of 25% off your first order. Just go to beekeepersnaturals.com/HYMAN and enter the code HYMAN. Try BiOptimizers Magnesium Breakthrough for 10% off by going to magbreakthrough.com/hyman and using the code HYMAN10. Right now, you can try out Cozy Earth’s bamboo pajamas and loungewear for 40% off—their highest discount ever offered. Just go to cozyearth.com and use the code HYMANPODCAST Here are more of the details from our interview (audio version / Apple Subscriber version): Why Alzheimer’s is a systems biology disorder that needs to be treated from a Functional Medicine perspective (7:13 / 4:01) Four main drivers of cognitive decline (12:01 / 8:10) The ineffectiveness of seeking just one cause of Alzheimer’s (13:05 / 9:08) Personalizing Alzheimer's treatment and prevention (19:42 / 15:08) The 4 stages of Alzheimer's (21:19 / 17:30) Eating and fasting to prevent, slow, and reverse cognitive decline (27:51 / 21:44) The importance of exercise, sleep, and stress reduction in relation to brain health (32:31 / 26:41) Reversing Alzheimer’s and pre-Alzheimer’s disease (39:38 / 33:49) Patient stories of cognitive improvement after Alzheimer’s diagnosis (47:04 / 41:25) Breaking through the conventional perspective and approach to Alzheimer’s disease (54:01 / 48:33) Learn more about Dr. Bredesen’s work at https://www.apollohealthco.com/ Get a copy of Dr. Bredesen’s book, The First Survivors of Alzheimer’s: How Patients Recovered Life and Hope in Their Own Words here.

This episode is brought to you by Rupa Health and Athletic Greens. If you have a chronic illness, you’ve got inflammation. Inflammation is often hidden or silent, something that we can’t see or feel, but manifests itself as heart disease, cancer, diabetes, depression, and more. Typically, inflammation has been raging inside for a while before you even notice there’s anything wrong. The three biggest drivers of inflammation are all lifestyle factors—gut health, diet, and chronic stress. In this episode of my new Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about inflammation, what’s causing it, and how to reduce it. We discuss the critical component of gut health and how 60-70% of our immune system is in our gut, as well as tests to identify inflammation in the body, foods to avoid, and the importance of restful sleep. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, Dhru Purohit Podcast, is a top 50 global health podcast with over 30+ million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here. Right now, Athletic Greens is offering my listeners 10 free travel packs of AG1 when you make your first purchase. Just go to athleticgreens.com/hyman to take advantage of this great offer. In this episode, we discuss (audio version / Apple Subscriber version): What is inflammation? (4:40 / 1:10) Three biggest drivers of inflammation (6:00 / 2:46) Detecting inflammation in patients (25:02 / 21:31) Conventional medicine approach to treating inflammation (28:16 / 24:50) Foods that are inflammatory (30:43 / 27:11) Sleep apnea’s association with inflammation (34:55 / 31:21) My personal experience with gut dysfunction and its connection to inflammation (44:25 / 41:02) Testing for inflammation (50:30 / 46:59) Supplements to reduce inflammation (53:50 / 50:28) Your questions on addressing grains, hormones, genetics, and more (59:25 / 55:50)

This episode is brought to you by Rupa Health and Cozy Earth. Most of us can relate to feeling tired, moody, or just overall depleted. It’s not a lack of willpower or motivation that leads to low-energy. It's because we’re up against energy thieves that are hiding everywhere from our immune system to the food we eat, and even our microbiome. In this compilation episode, I talk to Dave Asprey about using the principles of Functional Medicine and the biology of biohacking to boost energy, promote weight loss, and feel good at any age. We discuss the numerous benefits of fasting, such as reducing insulin, improving brain function, and supporting mitochondria (these are our tiny but powerful cellular energy factories)​​. Fasting doesn’t have to mean feeling stressed, tired, or even hungry—Dave tells us how to remove the fear and pain some people feel about fasting to make the process easier. Dave Asprey is the founder and Chairman of Bulletproof 360, a high-performance coffee and food company, and creator of the widely-popular Bulletproof Coffee. He is a three-time New York Times bestselling author, host of the Webby award-winning podcast Bulletproof Radio, and has been featured on the Today show, Fox News, Nightline, CNN, and dozens more. Over the last two decades Dave, the “Father of Biohacking,” has worked with world-renowned doctors, researchers, scientists, and global mavericks to uncover the latest, most innovative methods, techniques, and products for enhancing mental and physical performance. This episode is brought to you by Rupa Health and Cozy Earth. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here. Right now, you can try out Cozy Earth’s bamboo pajamas and loungewear for 40% off—their highest discount ever offered. Just go to cozyearth.com and use the code HYMANPODCAST.

This episode is brought to you by Paleovalley, Athletic Greens, and Tushy. I don’t like to look at what I do as treating disease. I’d rather look at it as creating health. And we have a lot of power to do that ourselves, each and every day. This is something I especially like to remind people of as we continue through the pandemic—the right choices and habits can help us stay more resilient and healthy during what feels like an uncontrollable world health crisis. Today on The Doctor’s Farmacy, I talk to my good friend Ken Cook, as part of EWG’s CleanCon Conference. In this conversation, Ken interviews me about establishing better habits for human and planetary health. Ken Cook is widely recognized as one of the environmental community’s most prominent and influential critics of industrial agriculture and the nation’s broken approach to protecting families and children from toxic substances. Under Cook’s leadership, EWG has pioneered the use of digital technologies to empower American families with easy-to-use, science-driven tools to help reduce their exposure to potentially harmful ingredients in food, drinking water, cosmetics, and other household products. This episode is brought to you by Paleovalley, Athletic Greens, and Tushy. Paleovalley is offering 15% off your entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Athletic Greens is offering my listeners 10 free travel packs of AG1 when you make your first purchase at athleticgreens.com/hyman. Visit hellotushy.com and enter code HYMAN to save 10% off any Hello TUSHY purchase site-wide, including the new TUSHY Ace. Here are more of the details from our interview (audio version / Apple Subscriber version): The connection between poor diet and Covid-19 outcomes (4:53 / 1:48) Environmental toxins and the immune system (7:05 / 3:19) My journey into understanding the power of nutrition and health (8:15 / 4:13) My approach to working with patients to promote behavior change (12:29 / 8:46) Improving your diet to improve your health (18:12 / 14:11) Creating structure to support healthy habits and behavior change (20:30 / 16:50) Understanding your body as one interconnected ecosystem (25:12 / 21:04) Becoming Covid-resistant (29:18 / 24:04) Learn more about the Environmental Working Group at ewg.org and follow EWG on Facebook @ewg.org, on Instagram @environmentalworkinggroup, and on Twitter @ewg.

This episode is brought to you by Rupa Health and ButcherBox. As the science of longevity has exploded in recent years, we have more access to innovative therapies, techniques, knowledge, and technology than ever before. Traditionally, we view aging as an inevitable consequence that happens to our bodies as we get older. We think that as we gain more years of life, it is a given that we begin to slow down, become less agile, lose our memories, and gain more chronic diseases. We define these things as “aging” when they’re actually signs of dis-ease that can be prevented and often even reversed. In this episode of my new MasterClass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about creating vibrant, optimal health, to feel younger at any age. We discuss the latest science on whole-body health and longevity and share simple, accessible tips that you can use right now to start feeling younger at any age. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, Dhru Purohit Podcast, is a top 50 global health podcast with over 30+ million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and ButcherBox. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here. This holiday, ButcherBox is proud to give new members 2 pounds of ground beef in your first box plus $10 off. To receive this offer, go to ButcherBox.com/farmacy. In this episode, we discuss (audio version / Apple Subscriber version): Reversing your biological age (4:48 / 1:29) The difference between healthspan and lifespan (10:22 / 6:45) Threats to aging well, including insulin resistance, sarcopenia, inflammation, and more (12:55 / 9:30) Addressing the root cause of disease using Functional Medicine (18:42 / 15:27) Learnings about longevity from the Blue Zones (23:16 / 20:00) Eating well for a longer life (28:02 / 24:08) Why prioritizing your sleep is vital (35:35 / 32:13) Using supplements to optimize all the systems of your body (40:32 / 36:57) The importance of relationships and community (45:03 / 41:28) Your questions on addressing early aging, exercise, stress, and more (59:24 / 55:55) Mentioned in this episode: Dr. Hyman at 40 yrs vs. 60 yrs https://www.instagram.com/p/CVAp0fqFhX1/ EMF Bed Canopies https://safelivingtechnologies.com/products/bed-canopies/ Dr. Hyman+ (which includes access to the Longevity Roadmap docuseries) https://drhyman.com/plus/

This episode is sponsored by Rupa Health and Athletic Greens. While inflammation is a natural part of life that can serve a beneficial role, we start to see disease when inflammatory pathways are constantly activated. That’s why many brain symptoms—like brain fog, anxiety, memory loss, and more—can actually be caused by systemic inflammation. The foods we eat, the toxins we’re exposed to, our stress levels, and our genetics are just some of the many aspects that can impact the body—and the brain’s—propensity towards inflammation. In this episode, I discuss inflammation in the brain with Dr. Todd LePine. We dive into the many factors that can drive neuroinflammation, the range of conditions that are linked to brain inflammation, and how we work with patients to cool this inflammation. I also talk with Max Lugavere about how nutritional deficiencies affect the brain. Dr. Todd LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medicine, and is an Institute for Functional Medicine Certified Practitioner. He has been practicing Functional Medicine for over 15 years focusing on Optimal Aging, Bio-Detoxification, Gastrointestinal Health, Systemic Inflammation, Autoimmune disorders and the Neurobiology of mood and cognitive disorders. Max Lugavere is a filmmaker, health, and science journalist and the author of the New York Times bestselling book Genius Foods: Become Smarter, Happier, and More Productive While Protecting Your Brain for Life. He is also the host of the #1 iTunes health podcast The Genius Life. Max’s sophomore book is The Genius Life: Heal Your Mind, Strengthen Your Body, and Become Extraordinary, a lifestyle guide to living happily and healthily with proven, research-based lifestyle tactics, which we dig into more throughout this episode. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here. Athletic Greens is offering my listeners 10 free travel packs of AG1 when you make your first purchase here.

This episode is brought to you by Joovv, BiOptimizers, and Cozy Earth. Meat is always a hot topic in the nutrition and wellness space. To eat it, or not to eat it? That is the oversimplified question of what is a much more complex topic. You see, we can’t lump all meat into one category. And we can’t think about meat as all or nothing—there’s much more to the story. Today on The Doctor’s Farmacy, Scott Lively and I talk all about conscious meat-eating, and more specifically beef, as well as the nuances that come with it. Scott shares some helpful tips for improving the quality of the meat you eat. Scott Lively is the co-founder of Raise American, which provides 100 percent grass-fed, organic, American, planet-friendly beef. He is an organic food entrepreneur and an absolute beef freak. Scott left a successful career in the IT industry to co-found what is now the largest organic beef company in the United States. Today, he oversees a broad portfolio of companies, private labels, and brands. Scott is an advocate of local economic development and regenerative farming practices applied to large agriculture. He is the author of For The Love of Beef: the Good, the Bad and the Future of America’s Favorite Meat. This episode is brought to you by Joovv, BiOptimizers, and Cozy Earth. For a limited time, Joovv is offering $50 off your first order with the code FARMACY at Joovv.com/FARMACY. Some exclusions apply. Try BiOptimizers Magnesium Breakthrough for 10% off by going to magbreakthrough.com/hyman and using the code HYMAN10. Right now, you can try out Cozy Earth’s bamboo pajamas and loungewear for 40% off—their highest discount ever offered. Just go to cozyearth.com and use the code HYMANPODCAST. Here are more of the details from our interview (audio version / Apple Subscriber version): How “Big Beef” gained its negative reputation (5:46 / 1:38) Issues and challenges with the current beef industry (10:43 / 6:39) Consumer driven change in the beef industry (12:13 / 8:40) Health attributes of grass-fed beef (14:21 / 10:34) Meat consumption and planetary health (21:09 / 17:22) Improving beef quality and agricultural practices through academic and governmental programming (29:36 / 25:12) Are lab-based meat alternatives good for us? (34:39 / 30:42) Tips to determine meat quality (43:31 / 37:47) Scott’s journey into the beef industry (48:15 / 42:31) The difference between organic and grass-fed beef (52:13 / 46:27) Is regenerative agriculture scalable? (55:01 / 49:16) Get a copy of Scott’s book, For The Love of Beef: the Good, the Bad and the Future of America’s Favorite Meat here https://www.fortheloveofbeef.com. Learn more about The Conservation Reserve Enhancement Program (CREP) here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on leaky gut with Dr. Cindy Geyer. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health and InsideTracker. At every meal, we make choices of what to feed our bodies—and our brains. Too much sugar and refined carbs, not enough good fats, inadequate intake of the right nutrients, and exposure to toxins can have a negative effect on our brains and even contribute to disorders ranging from brain fog to depression to Alzheimer’s. Nutrients are the fertilizer for the brain. When we get the right kinds, our brain can flourish and grow, even generating new cells in older age, long after science previously thought was possible. In this episode of my new MasterClass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about using diet and lifestyle to support brain health. We also talk about why it’s important to treat the body when it comes to treating brain issues, and I share my own experience using Functional Medicine to heal my own brain. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, Dhru Purohit Podcast, is a top 50 global health podcast with over 30+ million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and InsideTracker. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here. Save $200 on InsideTracker’s Ultimate Plan + Free InnerAge and enjoy 25% off as part of their Black Friday Sale here. In this episode, we discuss (audio version / Apple Subscriber version): What to eat, and not to eat, for brain health (4:10 / 00:56) How and why inflammation affects the brain (10:30 / 7:19) Fixing the body to fix the brain (12:59 / 9:45) The importance of exercise, sleep, and stress management (14:46 / 11:21) Dr. Hyman’s personal brain health story (19:37 / 16:23) The dangers of environmental toxins (26:08 / 22:32) Sugar’s effect on the brain (35:58 / 32:42) Case studies (39:01 / 35:48) Supplements to support brain health (50:09 / 46:56) Your questions on foods, energy, caffeine, and more (51:51 / 48:41)

This episode is brought to you by Rupa Health and Paleovalley. If I had one “medicine” to take with me anywhere in the world to heal people it would be food. Real food contains thousands of molecules, each designed to regulate and optimize the functions of your body—your gene expression, hormones, brain chemistry, immune system, gut microbiome, and more. In this episode, I talk to Tom Bilyeu, Lewis Howes, Dr. Elizabeth Boham, Dr. Shebani Sethi Dalai, and Fred Provenza about the power of using food as medicine. Tom Bilyeu is a filmmaker and serial entrepreneur who chased money hard for nearly a decade and came up emotionally bankrupt. To that end, he and his partners sold their technology company and founded Quest Nutrition—a company predicated not on money, but rather on creating value for people with the mission to end metabolic disease, something impacting Tom’s own family. Bilyeu then turned his attention to the other pandemic facing society, the poverty of poor mindset and co-founded the media studio, Impact Theory with his business partner and wife, Lisa Bilyeu. Lewis Howes is a New York Times Bestselling author of the hit book, The School of Greatness. He is a lifestyle entrepreneur, high-performance business coach, and keynote speaker. A former professional football player and two-sport All-American, he is a current USA Men’s National Handball Team athlete. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women’s Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. Dr. Shebani Sethi Dalai is a double board-certified physician in Obesity Medicine and Psychiatry. She is the Founding Director of Stanford University's Metabolic Psychiatry program and Silicon Valley Metabolic Psychiatry, a new center in the San Francisco Bay Area focused on optimizing brain health by integrating low-carb nutrition, comprehensive psychiatric care, and treatment of obesity with associated metabolic disease. Fred Provenza is professor emeritus of Behavioral Ecology in the Department of Wildland Resources at Utah State University where he worked for 35 years, directing an award-winning research group that pioneered an understanding of how learning influences foraging behavior and how behavior links soil, plants, herbivores, and humans. He is the author of three books, including Nourishment: What Animals Can Teach Us about Rediscovering Our Nutritional Wisdom; Foraging Behavior: Managing to Survive in a World of Change; and The Art & Science of Shepherding: Tapping the Wisdom of French Herders (co-written with Michel Meuret). This episode is brought to you by Rupa Health and Paleovalley. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. Check out a free live demo with a Q&A or create an account here. Paleovalley is offering 15% off your entire first order at paleovalley.com/hyman.

This episode is brought to you by BiOptimizers, Athletic Greens, and TUSHY. If you’ve experienced any of the symptoms of hormonal imbalance, you’d probably agree that they have a lot of power over how well we feel. But unfortunately, especially for women, the signs of hormonal imbalances are constantly being written off as “normal.” I’m here to tell you that they’re not! Today, I’m talking with Dr. Sara Gottfried about why our hormones get out of whack and how to get them back in balance. Dr. Sara Gottfried is a board-certified physician who graduated from Harvard and MIT. She practices evidence-based integrative, precision, and Functional Medicine. She is a Clinical Assistant Professor in the Department of Integrative Medicine and Nutritional Sciences at Thomas Jefferson University, and Director of Precision Medicine at the Marcus Institute of Integrative Health. Her three New York Times bestselling books include: The Hormone Cure, The Hormone Reset Diet, and Younger. Her latest book is called Women, Food, and Hormones. Here are more of the details from our interview (audio version / Apple Subscriber version): We need to stop normalizing women’s hormonal issues (4:24 / 1:58) Weight gain and hormonal issues (8:40 / 4:50) Symptoms of hormonal imbalance (9:53 /6:43) How food affects hormone balance (10:41 / 7:26) Alcohol and hormones (14:54 / 9:42) Hormone balancing foods (15:46 / 12:45) The importance of metabolic flexibility (20:26 / 15:37) Cruciferous vegetables, soy, and hormonal health (22:33 / 17:41) Is a plant-based or vegan diet helpful for hormonal health? (29:33 / 24:54) Why muscle is so important for hormonal health (32:31 / 27:45) Find out more about Dr. Gottfried at https://www.saragottfriedmd.com and learn more about becoming a patient of Dr. Gottfried’s Precision Medicine practice at https://marcusinstitute.jeffersonhealth.org/. Get Dr. Gottfried’s book, Women, Food, and Hormones: A 4-Week Plan to Achieve Hormonal Balance, Lose Weight, and Feel Like Yourself Again here.