The Dr. Hyman Show

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content. Mentioned in this episode Beeya Wellness Seed Cycling

This episode is brought to you by Rupa Health, InsideTracker, and FOND Bone Broth. Omega-3 is a fatty acid your body uses in all kinds of ways. Its benefits for our body are hard to overstate. But unlike most fats, your body can’t manufacture omega-3. Instead, it’s an “essential nutrient,” which means the only way to get it is through your diet. In today’s episode, I talk with Paul Greenberg, Dr. Andrew Huberman, and Dr. Daniel Amen about the importance of essential fatty acids like omega-3 for sleep, brain and heart health, and more. Paul Greenberg is the bestselling author of Four Fish, American Catch, and The Omega Principle. A regular contributor to the New York Times and many other publications, Mr. Greenberg is the writer-in-residence at the Safina Center, a Pew Fellow in Marine Conservation, and the recipient of a James Beard Award for Writing and Literature. Dr. Andrew Huberman is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award in 2017, which is given to the scientist making the largest discoveries in the study of vision. Work from the Huberman Laboratory at Stanford University School of Medicine has been published in top journals including Nature, Science, and Cell and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets. Dr. Daniel Amen is a physician, double-board-certified psychiatrist, 12-time New York Times bestselling author, and founder and CEO of Amen Clinics, with 10 US locations. Dr. Amen is the author of many books including the mega-bestseller Change Your Brain, Change Your Life, as well as The End of Mental Illness, Memory Rescue, Healing ADD, and Your Brain Is Always Listening. His new book, You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type, is now available. This episode is brought to you by Rupa Health, InsideTracker, and FOND Bone Broth. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. To experience the amazing health benefits of FOND Bone Broth, go to fondbonebroth.com/drhyman and use code HYMAN20 to get 20% off your purchase. Full-length episodes of these interviews can be found here: Paul Greenberg Dr. Andrew Huberman Dr. Daniel Amen

This episode is brought to you by Thrive Market and Athletic Greens. For years well-meaning doctors, echoed by the media, have emphasized what they have long believed is the intimate link between cholesterol and death by heart disease. If only it were so simple! You may hope that if you monitor your cholesterol levels and avoid the foods that are purported to raise cholesterol, you’ll be safe from America’s number-one killer. The truth is much more complex. Cholesterol is only one factor among many—and it’s not even the most important one—that contribute to your risk of getting heart disease. In today’s episode of my series I’m calling Health Bites, I talk about why standard cholesterol testing is outdated and why cholesterol may not be the cause of heart disease. This episode is brought to you by Thrive Market and Athletic Greens. Thrive Market is an online membership-based grocery store that makes eating well convenient and more affordable. Join today at thrivemarket.com/hyman to receive a FREE gift worth $60. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What is cholesterol? (4:36 / 1:48) The myth around cholesterol and dietary fat (5:06 / 2:25) The biggest source of abnormal cholesterol is not fat—it’s sugar (7:43 / 4:58) How lifestyle, environmental influences, and genetics influence cholesterol (8:28 / 5:44) Key contributors to heart disease (11:05 / 8:19) Tests to determine your risk for cardiovascular disease (13:13 / 10:24) How to lower your risk of heart disease and fix your cholesterol (16:58 / 14:10) The benefits, side effects, and risks of taking statin drugs (18:30 / 15:53) Mentioned in this episode Cleerly Sleep-hygiene blogs

This episode is brought to you by Cozy Earth, InisdeTracker, and Rupa Health. If you or a loved one struggle with addiction, this is an episode you’re going to want to listen to. Many of our current pharmaceuticals stem from compounds discovered in plant medicines. And many beneficial plants that were discovered decades ago still have huge potential for changing modern medicine—ibogaine is one of them. Today on The Doctor’s Farmacy, I’m excited to sit down with Dr. Deborah Mash to discuss the use of the African plant ibogaine and its metabolite, noribogaine, in the treatment of addiction and how it could impact the devastating opioid epidemic. Dr. Deborah Mash is one of the world's foremost experts on ibogaine. She is the CEO and Founder of DemeRx Inc., a clinical-stage drug development company advancing ibogaine and its active metabolite noribogaine for the treatment of opioid use disorder. DemeRx has partnered with ATAI Life Sciences—a global biotech platform with a special focus on psychedelic medicine—to develop ibogaine for those suffering from opioid use disorder. Building on the extensive human data available around ibogaine, DemeRx and ATAI are conducting a Clinical Phase I/II trial in opioid-dependent patients. This landmark trial will advance screening procedures, dosing guidelines, and best practices for opioid withdrawal management and relapse prevention. This episode is brought to you by Cozy Earth, InisdeTracker, and Rupa Health. Cozy Earth makes the most comfortable, temperature-regulating, and nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Here are more details from our interview (audio version / Apple Subscriber version): The long history of ibogaine’s ethnobotanical and ethnopharmacological use (7:01 / 4:10) The power of ibogaine to reset opioid tolerance and bypass many withdrawal symptoms in a single dose (15:41 / 8:11) How ibogaine works (20:59 / 14:15) Using ibogaine to protect against future relapse (26:09 / 19:25) Efforts to understand the importance of ibogaine’s psychedelic effects (30:05 / 24:54) Assessing the success rates of recovery and relapse prevention from ibogaine treatment (37:49 / 34:02) Understanding the underlying drivers of addiction for better recovery and relapse treatment (41:46 / 37:55) The concept of “psychoplastogens” and turning on synaptic plasticity in the brain (51:44 / 47:52) Humanity’s relationship to plants and plant medicines (57:25 / 53:34) Risks associated with and considerations for seeking ibogaine treatment (1:03:24 / 59:37) Learn more about Dr. Mash’s work at demerx.com.

This episode is brought to you by Rupa Health, Paleovalley, and HigherDOSE. Gluten is one ingredient we all love in bread or our favorite pizza dough, but it’s often the cause of inflammation and leaky gut, which is implicated in so many health conditions such as IBS, skin problems, Hashimoto’s, high blood pressure, and more. And it is not just people with celiac disease who are affected. In today’s episode, I talk with Maggie Ward, Dr. Alessio Fasano, and Dr. George Papanicolaou about how gluten affects the gut and how to know if it's a problem for you. Maggie Ward, MS, RD, LDN, is the Nutrition Director at The UltraWellness Center. Maggie holds a master’s degree in Nutrition from Bastyr University, which focuses on using whole foods for holistic nutrition therapy. She completed her requirements to become a registered dietitian at Westchester Medical Center in New York. Prior to joining The UltraWellness Center team in 2008, Maggie worked at the Brooklyn Hospital Center in New York. Advancing innovation in research, clinical care, and education, Alessio Fasano, MD, has dedicated his life to improving the quality of life for people with celiac disease and other gluten-related disorders. He founded the Center for Celiac Research at the University of Maryland School of Medicine in 1996. In 2013, he moved the center to Massachusetts General Hospital and renamed it the Center for Celiac Research and Treatment. He is chief of the Division of Pediatric Gastroenterology and Nutrition at Massachusetts General Hospital for Children and a professor of pediatrics at Harvard Medical School. Dr. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is board certified in family medicine from Abington Memorial Hospital. Upon graduation from his residency, he joined the Indian Health Service. In 2000, he founded Cornerstone Family Practice in Rowley, MA. He began training in Functional Medicine through the Institute for Functional Medicine. In 2015, he established Cornerstone Personal Health—a practice dedicated entirely to Functional Medicine. Dr. Papanicolaou joined The UltraWellness Center in 2017. This episode is brought to you by Rupa Health, Paleovalley, and HigherDOSE. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Right now, get your own Infrared Sauna Blanket or Infrared PEMF Mat at HigherDOSE.com and use my exclusive promo code FARMACY15 at checkout to save 15% off. Full-length episodes of these interviews can be found here: Maggie Ward Dr. Alessio Fasano Dr. George Papanicolaou

This episode is brought to you by Rupa Health and Athletic Greens. Hidden inflammation is at the root of all chronic illness—conditions like heart disease, obesity, diabetes, dementia, depression, cancer, and even autism. So if inflammation is at the root of most modern diseases, how do we find the causes and get the body back in balance? First, we need to identify the triggers and causes of inflammation. Then we need to help reset the body’s natural immune balance by providing the right conditions for it to thrive. In today’s episode of my series I’m calling Health Bites, I am talking about inflammation, how it’s linked to everything from obesity to all of the chronic diseases of aging, and how to combat it. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What is inflammation, and why can it become so dangerous? (3:36 / 00:54) The problem with common treatments such as anti-inflammatory drugs and steroids (8:05 / 5:23) Testing to determine if you are suffering from hidden inflammation (9:40 / 6:58) The biggest drivers of inflammation (11:06 / 8:22) Steps to living an anti-inflammatory lifestyle (15:48 / 13:06) Environmental Working Group Gut Food

This episode is brought to you by ButcherBox, FOND Bone Broth, and InsideTracker. I know many of us can relate to feeling disconnected from each other, the natural world, and the things that really matter in life. So how did we lose our way and how can we make better sense of the world? It takes some inner work but also means cultivating truth and connecting with community, in order to reshape our narrative and change the collective conversation and state of the world. Today on The Doctor’s Farmacy, I have a deep conversation on rediscovering meaning with Jamie Wheal, about reclaiming our inner passion, courage, and conviction. Jamie Wheal is the author of Recapture the Rapture: Rethinking God, Sex and Death In a World That's Lost Its Mind and the global bestseller Stealing Fire: How Silicon Valley, Navy SEALs, and Maverick Scientists Are Revolutionizing the Way We Live and Work and the founder of the Flow Genome Project, an international organization dedicated to the research and training of human performance. This episode is brought to you by ButcherBox, FOND Bone Broth, and InsideTracker. ButcherBox makes it easy to get humanely raised meat and wild-caught, sustainable seafood by delivering it right to your doorstep. If you sign up at butcherbox.com/farmacy, ButcherBox will give you two pounds of ground beef for one whole year. FOND Bone Broth brews up the best bone broth I've ever tasted. To experience the amazing health benefits for yourself, go to fondbonebroth.com/drhyman and use code HYMAN20 to get 20% off your purchase. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from the episode (audio version / Apple Subscriber version): What does it mean to recapture the rapture? (8:43 / 3:40) Personal growth vs self-indulgence (10:33 / 7:44) How the foundations of our understanding of the world are collapsing and transforming (23:39 / 19:35) Finding meaning and purpose in our modern world (30:00 / 24:30) The power of healing in community (33:38 / 25:42) Using breathwork, embodiment, sexuality, substances, and music to help us reconnect to ourselves and each other (37:31 / 33:14) Applying the tools of Hedonic Engineering to real lives and relationships (57:16 / 53:10) Research Jamie conducted with real-life couples (1:09:24 / 1:05) Why we need ethical guidelines to steer through our own personal explorations (1:19:16 / 1:15:02) Ten ethical guidelines that Jamie developed (1:22:22 / 1:16:40) Get a copy of Jamie’s book, Recapture the Rapture: Rethinking God, Sex, and Death in a World That's Lost Its Mind, here.

This episode is brought to you by Rupa Health, InsideTracker, and Pique Life. Instead of using a pharmaceutical drug, what if your doctor knew how to look deeper to find out what is causing your depression, ADHD, or anxiety? While there is a time and a place for drugs, they can have significant side effects and may not be as effective at correcting an underlying imbalance in the body. Functional Medicine practitioners look at gut health, genes, diet, hormones, and so much more to create a thorough healing plan. In today’s episode, I talk with Dr. Uma Naidoo, Dr. George Papanicolaou, and Dr. Drew Ramsey about how diet and lifestyle can be both a cause of and treatment for depression and other mental health issues. Dr. Uma Naidoo is a Harvard-trained psychiatrist, professional chef, and nutrition specialist. In her role as a clinical scientist, Dr. Naidoo founded and directs the first hospital-based clinical service in nutritional psychiatry in the US. She is the Director of Nutritional and Lifestyle Psychiatry at Massachusetts General Hospital (MGH) and Director of Nutritional Psychiatry at the Massachusetts General Hospital Academy while serving on the faculty at Harvard Medical School. Dr. Naidoo is the author of This is Your Brain on Food. ⁣ Dr. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is board certified in family medicine from Abington Memorial Hospital. Upon graduation from his residency, he joined the Indian Health Service. In 2000, he founded Cornerstone Family Practice in Rowley, MA. He began training in Functional Medicine through the Institute for Functional Medicine. In 2015, he established Cornerstone Personal Health—a practice dedicated entirely to Functional Medicine. Dr. Papanicolaou joined The UltraWellness Center in 2017. Dr. Drew Ramsey is a psychiatrist, author, farmer, and founder of the Brain Food Clinic in New York City, offering treatment and consultation for depression, anxiety, and emotional wellness concerns. He is the author of three books, most recently the award-winning cookbook Eat Complete: The 21 Nutrients That Fuel Brain Power, Boost Weight Loss, and Transform Your Health. This episode is brought to you by Rupa Health, InsideTracker, and Pique Life. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Pique is offering up to 20% off plus free shipping on their Pu'er bundles at piquelife.com/farmacy. Full-length episodes of these interviews can be found here: Dr. Uma Naidoo Dr. George Papanicolaou Dr. Drew Ramsey

This episode is brought to you by Rupa Health and Athletic Greens. “Fatty liver” literally means your liver fills with fat, which paves the way for chronic disease and inflammation. Fatty liver is a dangerous yet misunderstood disease. It is also very common, affecting 90 million Americans alone. You need a healthy liver to combat toxic junk and chemicals in your environment. A healthy liver means your body stays healthy, you don’t get sick, and you maintain plenty of energy. A fatty liver, on the other hand, has numerous repercussions including inflammation, which triggers insulin resistance and prediabetes, meaning your body deposits fat in your liver and organs, including your belly (called visceral fat). Fatty liver can also lead to more serious problems including high triglycerides, low HDL (“good” cholesterol), and high amounts of small LDL (dangerous cholesterol particles that can cause heart attacks). Fatty liver also increases your heart attack risk. In today’s episode of my series I’m calling Health Bites, I am talking about how to identify if you have fatty liver, what’s causing it, and how to fix it. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What is fatty liver disease? (4:16 / 00:40) Causes of fatty liver disease (5:23 / 2:25) How to know if you have fatty liver disease (5:51 / 2:54) The dangers of fatty liver disease (6:57 / 4:06) Fructose and fatty liver (8:57 / 5:55) Foods to avoid and to eat to fix a fatty liver (10:31 / 7:42) Supplements to support the liver (12:41 / 9:44) Detoxifying, liver-repairing superfoods (13:54 /10:26)

This episode is brought to you by Cozy Earth, BiOptimizers, and InsideTracker. For decades, I’ve been on a mission to help my patients understand that weight loss is not about “calories in, calories out”. There are a multitude of factors that play into how our body makes, stores, and burns fat and the actual amount of calories we eat is one small drop in the bucket of our complex biology. Today, I’m excited to talk with Dr. Casey Means about the main drivers people face when struggling to lose weight and what we can do about them. Dr. Casey Means is a Stanford-trained physician, Chief Medical Officer, and Co-founder of metabolic health company Levels, an Associate Editor of the International Journal of Disease Reversal and Prevention, and a Lecturer at Stanford University. Her mission is to maximize human potential and reverse the epidemic of preventable chronic disease by empowering individuals with tools that can facilitate a deep understanding of our bodies and inform personalized and sustainable dietary and lifestyle choices. Dr. Means’ perspective has been featured in the New York Times, Wall Street Journal, Men's Health, Forbes, Business Insider, Techcrunch, Entrepreneur Magazine, Metabolism, Endocrine Today, and more. This episode is brought to you by Cozy Earth, BiOptimizers, and InsideTracker. Cozy Earth makes the most comfortable, temperature-regulating, nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Magnesium Breakthrough really stands out from the other magnesium supplements out there. BiOptimizers is offering my community 10% off, so just head over to magbreakthrough.com/hyman with code hyman10. ​​InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): The top reasons for resistance to weight loss beyond food, sleep, stress management, and exercise (5:41 / 2:30) Obesogens, obesity, and resistance to weight loss (11:41 / 8:50) Common sources of toxins in our daily lives (13:57 / 9:45) How toxins negatively affect our health (14:44 / 12:10) Why detoxification is an important component of weight loss (17:45 / 15:00) Limiting our toxic exposure (18:49 / 16:26) The role of micronutrients in resistance to weight loss (29:33 / 25:16) Tips for grocery shopping for micronutrients (40:02 / 35:50) The impact of light on our metabolism (47:29 / 43:14) Using a continuous glucose monitor to improve your metabolic health (55:36 / 51:35) For a limited time only, if you sign up for Levels at levels.link/HYMAN, you'll receive five exclusive longevity strategies from me and Dr. Casey Means.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on stopping stress with your vagus with Dr. Titus Chiu. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, Paleovalley, and InsideTracker. Your gut is your inner garden—the more good bugs you have in it the more likely it is to flourish. Our gut bacteria regulate many of our bodily functions, from creating vitamins to controlling our immune system, our brain function, and, of course, our metabolism and weight. They are critical to our long-term health. But even if you’re eating the right things, you may need some outside assistance maintaining plentiful and diverse gut bacteria. Probiotics help populate your gut with beneficial bacteria, improving your sleep, daily elimination, brain health, and so much more. In today’s episode, I talk with Dhru Purohit, Dr. Tracy Shafizadeh, and Dr. Elizabeth Boham about probiotics, the importance of the gut microbiome starting in infancy, and why you should work with a skilled practitioner to choose the right probiotic for you. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. Dr. Tracy Shafizadeh is leading the work in understanding the infant microbiome. She is a nutritional scientist who helps new and expectant moms learn about creating healthy gut bugs in their babies. Dr. Shafizadeh received her Ph.D. in nutritional biology from the University of California, Davis, and spends her free time "loving the guts" out of her two boys. Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing. This episode is brought to you by Rupa Health, Paleovalley, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Full-length episodes of these interviews can be found here: Dhru Purohit Dr. Tracy Shafizadeh Dr. Elizabeth Boham

This episode is brought to you by Beekeeper’s Naturals and Athletic Greens. Your brain is an organ that’s connected to everything else happening in your body. Most of us never learn how to manage our energy and bodies. Instead, we use drugs like sugar, caffeine, and alcohol to self-medicate and manage our energy and moods. We don’t connect our behaviors and choices with how we feel. Many of us get too little good food, nutrients, light, air, water, rest, sleep, rhythm, exercise, community, love, meaning, and purpose. We’re exposed to far too much poor-quality food, stress, toxins, and allergens. But even if you manage all those things correctly, you still might not be getting the right amount of certain nutrients that support your brain and body. That’s where supplements come in. In today’s episode in my series I’m calling Health Bites, I am talking about how to heal our broken brains with the right nutrients. The brain is resilient and can recover and heal when given the right conditions. This episode is brought to you by Beekeeper’s Naturals and Athletic Greens. Right now, Beekeeper’s Naturals is giving my community an exclusive offer. Just go to beekeepersnaturals.com/HYMAN and enter code HYMAN to get 25% off your first order. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): Things that damage our brain (3:48 / 1:18) The top nutrients we need to support our brain health: multivitamins, Omega-3 fatty acids, magnesium, vitamin D, folate, B6, and B12, and probiotics (6:17 / 2:55) The gut-brain connection (11:26 / 8:55) The role of glutathione in brain function and how to boost it (12:24 / 9:46) Supporting mitochondria for brain health (13:14 / 10:42) Calming nutrients to support the brain (14:13 / 11:42)

This episode is brought to you by Rupa Health, BiOptimizers, and InsideTracker. Our relationships affect our health and happiness. The problem is that we’re never taught how to seek, create, nurture, and assess our relationships the same way we do our careers and bank accounts. But the cost of bad relationships on ourselves and our society truly adds up. The relationships many of us grew up around and might consider “normal” are in fact dysfunctional, creating a negative cycle we often don’t even realize we’re in. So how can we find good love, create good relationships, and keep them? That’s what today’s conversation with Mia Lux is all about. Mia merges the playful and the profound—drawing on her experience as a start-up CEO, stand-up comedian, personal growth junkie, and recovering lawyer. For over 7 years, Mia has been an international host, comedian & facilitator, specializing in designing and facilitating top wellness/personal development experiences around the world. Now, Mia is channeling this in the name of love as the Co-Founder & CEO of La Vette, a radical new platform designed to rehumanize dating in the digital era. This episode is brought to you by Rupa Health, BiOptimizers, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Magnesium Breakthrough really stands out from the other magnesium supplements out there. BiOptimizers is offering my community 10% off, so just head over to magbreakthrough.com/hyman with code hyman10. ​​InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): How our relationships affect our health and happiness (6:01 / 2:25) Shifting away from dysfunctional relationships toward intentional relationships (7:49 / 5:04) Self-inquiry to support healthy love relationships (14:07 / 11:30) Identifying the unconscious beliefs driving us into relationships (19:05 / 15:37) Letting go of good love and conscious uncoupling (25:11 / 20:02) Scientific predictors of relationship success (27:18 / 23:52) Interpersonal skills to improve your dating life and relationships (31:59 / 26:37) Speaking your truth in relationships (38:47 / 33:40) Navigating the dangers of dating (40:18 / 36:10) The importance of vulnerability and authenticity in dating and relationships (48:17 / 45:35) Learn more about LaVette and try your first month free at lavette.love/drhyman.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, InsideTracker, and Pique Tea. Hair loss is a commonly experienced issue and often signals something deeper going on in the body. And as there are many different types of hair loss, there are also many various drivers of hair loss, including hormonal imbalance, metabolic dysfunction, or even autoimmune disease. This is why Functional Medicine practitioners look at gut and metabolic health, nutrient status, and much more to find the root cause of hair loss. In today’s episode, I talk with Dr. Elizabeth Boham, Dhru Purohit, and Dr. Cynthia Li about the many different types of hair loss and their associated underlying causes. Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing, she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. Dr. Cynthia Li received her medical degree from the University of Texas Southwestern Medical Center in Dallas. She has practiced as an internist in settings as diverse as Kaiser Permanente Medical Center, San Francisco General Hospital, and St. Anthony Medical Clinic serving the homeless. Her personal health challenges led her to integrative and Functional Medicine, and she currently has a private practice in Berkeley, CA. She serves on the faculty of the Healer’s Art program at the University of California San Francisco School of Medicine, and she is the author of Brave New Medicine: A Doctor’s Unconventional Path to Healing Her Autoimmune Illness. This episode is brought to you by Rupa Health, InsideTracker, and Pique Tea. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Pique is offering up to 20% off plus free shipping on their Pu'er bundles. Just go to piquelife.com/farmacy for up to 20% off plus free shipping. Full-length episodes of these interviews can be found here: Dr. Elizabeth Boham Dhru Purohit Dr. Cynthia Li

This episode is sponsored by Paleovalley and Pendulum. Thyroid disease affects one in five women and one in ten men, yet 50 percent of people with thyroid disease go undiagnosed. The main role of thyroid hormone is to stimulate metabolism, and it affects almost every function of the body. That’s why thyroid imbalance can cause so many different symptoms. In today’s episode of a new series called Health Bites, I discuss thyroid disease and why an out-of-whack thyroid can stall your metabolism and create many other problems. I also share why using a whole-foods diet, nutritional supplements, and optimizing thyroid hormone replacement is critical for addressing thyroid disorders. This episode is sponsored by Paleovalley and Pendulum. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20. Here are more details from the episode (audio version / Apple Subscriber version): What is the thyroid gland and how does it function? (4:38 / 1:42) Symptoms of hypothyroidism (7:05 / 4:11) Diagnostic testing to assess thyroid function (8:42 / 4:54) What causes thyroid problems? (10:22 / 7:30) My approach to healing hypothyroidism (14:58 / 10:20) Thyroid-supporting foods and foods to avoid (15:15 / 12:20) Supplements that support your thyroid (17:00 / 14:04) Thyroid hormone replacement (17:46 / 14:50) If you suspect you have hypothyroidism, take a thorough inventory of any of the symptoms mentioned in the podcast to see if you might be suffering from hypothyroidism. get a full-spectrum thyroid test that includes TSH, free T3, free T4, TPO, and antithyroglobulin antibodies. check for celiac disease with a celiac panel. consider heavy metal toxicity testing. check your vitamin D level. Mentioned in this episode Self-Assessment Tool within The UltraThyroid Solution Workbook (Download here) EWG.org

This episode is brought to you by Rupa Health, InsideTracker, and Cozy Earth. If you’ve ever wondered if supplements are worthwhile or just create expensive urine, this is the podcast episode for you. While I wish it wasn’t the case, I do believe we need supplements to make up for the nutrients we can no longer get through food alone. It’s extra important to note, though, that not all supplements are created equal. And please keep in mind they’re called “supplements” for a reason, not “replacements”—they are meant to supplement a healthy diet and lifestyle to provide the most impact. Today, I’m excited to take a deeper dive into this topic with one of my most trusted sources when it comes to nutrition and dietary research, Chris Kresser. Chris Kresser M.S., L.Ac. is the co-founder of the California Center for Functional Medicine, the founder of Kresser Institute, the host of the top-ranked health podcast Revolution Health Radio, the creator of ChrisKresser.com, and the New York Times best-selling author of The Paleo Cure and Unconventional Medicine. Chris is one of the most respected clinicians and educators in the fields of Functional Medicine and ancestral health and has trained over 2,000 clinicians and health coaches from over 50 countries in his unique approach. He has recently launched Adapt Naturals, a supplement line designed to add back in what the modern world has squeezed out and help people perform and feel their best. This episode is brought to you by Rupa Health, InsideTracker, and Cozy Earth. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Cozy Earth makes the most comfortable, temperature-regulating, and nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Here are more details from our interview (audio version / Apple Subscriber version): Do we really need to take supplements? (5:14 / 1:54) Why our food is less nutritious than it used to be (13:32 / 10:10) Can you really get your nutrients from food? (15:28 / 12:10) The prevalence of, and most common, nutritional deficiencies (16:27 / 13:35) Testing your nutrient levels (21:35 / 18:25) Symptoms of common nutrient deficiencies (29:03 / 25:05) Can you take too much or overdose on nutrients? (41:57 / 36:58) What to look for in a quality vitamin or supplement (51:37 / 47:10) What nutrients are provided by plant vs animal foods (59:41 / 55:06) The most nutrient-dense foods (1:10:23 / 1:05:45) Learn more about Chris at ChrisKresser.com and check out his new supplement line, Adapt Naturals.

This episode is brought to you by Rupa Health, ButcherBox, and Mitopure. Sleep is a keystone of health. Most people know they should get more high-quality sleep, but they don’t really know where to start. But understanding the way our brain and neurotransmitters work means we can hack our sleep to not just feel amazing but to level up our focus, skills, and knowledge. And it’s not all about what happens at night, either—getting the right exposure to light at the right times has a profound impact on our circadian rhythms and the way our bodies transition to sleep. In today’s episode, I talk with Dr. Roger Seheult, Dhru Purohit, and Dr. Andrew Huberman about why optimizing your sleep should be prioritized and how you can get better sleep. Dr. Roger Seheult is currently an associate clinical professor at the University of California, Riverside School of Medicine, and an assistant clinical professor at the School of Medicine and Allied Health at Loma Linda University. Dr. Seheult is quadruple board certified in Internal Medicine, Pulmonary Diseases, Critical Care Medicine, and Sleep Medicine through the American Board of Internal Medicine. He is also the cofounder of MedCram, an online medical education company that helps healthcare professionals and laypeople understand medical topics clearly. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. Dr. Andrew Huberman is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award in 2017, which is given to the scientist making the largest discoveries in the study of vision. His lab’s most recent work focuses on the influence of vision and respiration on human performance and brain states such as fear and courage. Work from the Huberman Laboratory at Stanford University School of Medicine has been published in top journals including Nature, Science, and Cell and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets. This episode is brought to you by Rupa Health, ButcherBox, and Mitopure. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. If you sign up at butcherbox.com/farmacy, ButcherBox will give you 2lbs of ground beef free for one whole year. Get 10% off at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Full-length episodes of these interviews can be found here: Dr. Roger Seheult Dhru Purohit Dr. Andrew Huberman

This episode is sponsored by InsideTracker and Athletic Greens. Believe it or not, the surface area of your small intestine, which is where your food is absorbed, is the size of a tennis court. Your small intestine is also the home of your gut-immune system, which accounts for about 60 percent of your total immune system. The lining of this sophisticated system is just one cell layer away from a toxic sewer where all of the bacteria and undigested food particles live in your gut. If that lining breaks down—from stress; too many antibiotics or anti-inflammatory drugs like aspirin or ibuprofen; steroids; intestinal infections; a low-fiber, high-sugar diet; alcohol; and more—your immune system will be exposed to foreign particles from food, bacteria, and other microbes. This, in turn, creates havoc that can lead to an irritable bowel and other system-wide problems including allergies, arthritis, and autoimmune and mood disorders. In today’s episode of a new series called Health Bites, I discuss how to heal irritable bowel syndrome (IBS) and upregulate your gut health, which is at the forefront of Americans’ most common health complaints. This episode is sponsored by InsideTracker and Athletic Greens. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What is irritable bowel syndrome? (4:05 / 1:12) Symptoms of IBS (4:30 / 1:35) Causes of IBS (4:54 / 2:00) Identifying food allergies as the potential cause of IBS (8:00 / 5:11) How gut imbalance leads to IBS (9:36 / 6:44) Diagnostic testing to access gut health (12:14 / 9:25) What is SIBO, how does it cause IBS, and how is it diagnosed? (15:20 / 12:29) Assessing if yeast overgrowth is causing your gut issues (15:58 / 13:05) Treating yeast overgrowth and SIBO (16:40 / 13:50) Strategies for rebooting the gut and restoring optimal gut health (17:44 / 14:55)

This episode is brought to you by Rupa Health, InsideTracker, and FOND Bone Broth. Why are we seeing more chronic disease, stress, obesity, addiction, and so many other states of illness than ever before, despite having the most advanced medical system in the world? Because we aren’t living in a natural and normal world. We’re actually having normal responses to our abnormal circumstances, many of which create trauma that gets stored in the brain and body. Today on The Doctor’s Farmacy, I’m honored to talk to my dear friend Dr. Gabor Maté about the myth of normal, and why doing the difficult work of uncovering trauma is essential for living our fullest expression of life. A renowned speaker and bestselling author, Dr. Gabor Maté is highly sought after for his expertise on a range of topics including addiction, stress, and childhood development. Dr. Maté has written several bestselling books, including the award-winning In the Realm of Hungry Ghosts: Close Encounters with Addiction, When the Body Says No: Exploring the Stress-Disease Connection, and Scattered: How Attention Deficit Disorder Originates and What You Can Do About It, and has co-authored Hold On to Your Kids: Why Parents Need to Matter More Than Peers. His latest book, The Myth of Normal: Trauma, Illness & Healing in a Toxic Culture was just released. This episode is brought to you by Rupa Health, InsideTracker, and FOND Bone Broth. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. To experience the amazing health benefits of FOND Bone Broth, go to fondbonebroth.com/drhyman and use code HYMAN20 to get 20% off your purchase. Here are more details from our interview (audio version / Apple Subscriber version): Uncovering my personal trauma history (6:42 / 3:50) Scientific evidence linking trauma and stress to physical and mental illness (14:38 / 11:45) Social determinants of health (16:34 / 14:15) Our crisis of separation, disconnection, and loneliness (20:25 / 18:00) The link between addiction, our profit-driven culture, and trauma (25:16 / 22:20) The myth of normal (31:07 / 26:33) Tools, therapies, and resources for your own healing (49:50 / 45:41) Treating trauma with plant medicines and psychedelics (55:40 / 51:16) The biology of psychology (1:10:46 / 1:06:20) Gabor’s vision for our society (1:31:42 / 1:25:48) Learn more about Gabor Maté at drgabormate.com and get a copy of his new book, The Myth of Normal—Trauma, Illness, & Healing In a Toxic Culture, here.

This episode is brought to you by Rupa Health, Thrive Market, and Levels. We’ve been told that cognitive decline is inevitable, but researchers are discovering that we have more power over our aging brains than we once thought. What we eat, what we think, and how we live have incredible influence over the health of our brains—and our entire bodies. In today’s episode, I talk with Max Lugavere, Dr. Christopher Palmer, and Dr. Daniel Amen about foods that improve brain health, the link between our metabolic health and brain health, choosing happiness, and so much more. Max Lugavere is a health and science journalist and the author of the New York Times bestselling book Genius Foods: Become Smarter, Happier, and More Productive While Protecting Your Brain for Life, now published in 10 languages around the globe. His sophomore book, also a bestseller, is called The Genius Life: Heal Your Mind, Strengthen Your Body, and Become Extraordinary. Max is the host of a number-one iTunes health and wellness podcast called The Genius Life. Dr. Christopher Palmer is a psychiatrist and researcher working at the intersection of metabolism and mental health. He is the Director of the Department of Postgraduate and Continuing Education at McLean Hospital and an assistant professor of Psychiatry at Harvard Medical School. For over 25 years, he has held leadership roles in psychiatric education, conducted research, and worked with people who have treatment-resistant mental illnesses. He has been pioneering the use of the medical ketogenic diet in the treatment of psychiatric disorders—conducting research, treating patients, writing, and speaking around the world on this topic. Dr. Daniel Amen is a physician, double board-certified psychiatrist, twelve-time New York Times bestselling author, and founder and CEO of Amen Clinics, with 10 US locations. Dr. Amen is the author of many books including the mega-bestseller Change Your Brain, Change Your Life, as well as The End of Mental Illness, Memory Rescue, Healing ADD, and Your Brain Is Always Listening. His new book, You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type, is now available. This episode is brought to you by Rupa Health, Thrive Market, and Levels. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. Join Thrive Market today at thrivemarket.com/hyman to receive an extra $80 in free groceries with your first order. Learn more about Levels by going to levels.link/HYMAN. Full-length episodes of these interviews can be found here: Max Lugavere Dr. Christopher Palmer Dr. Daniel Amen

This episode is sponsored by ButcherBox and Athletic Greens. Think of magnesium as the relaxation mineral. Anything that is tight, irritable, crampy, and stiff—whether it is a body part or even a mood—can be a sign of magnesium deficiency. This critical mineral is actually responsible for over 600 enzyme reactions and is found in all of your tissues—but mainly in your bones, muscles, and brain. You must have it for your cells to make energy, for many different chemical pumps to work, to stabilize membranes, and to help muscles relax. Yet, so many of us are deficient in this important mineral. In today’s episode of a new series called Health Bites, I discuss why magnesium deficiency is a huge problem, why most of us are deficient, how to identify if you are magnesium deficient, and what to do about it. This episode is sponsored by ButcherBox and Athletic Greens. ButcherBox makes it easy to get humanely raised meat and wild-caught, sustainable seafood by delivering it right to your doorstep. If you sign up at butcherbox.com/farmacy, ButcherBox will give you two pounds of ground beef free for one whole year. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 free travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): Why magnesium deficiency is so prevalent (3:26 / 00:57) Signs of magnesium deficiency (4:11 / 1:48) Magnesium use in a traditional hospital setting (5:37 / 3:15) Testing your magnesium levels (7:26 / 5:02) Food sources of magnesium (7:51 / 5:27) Things that deplete magnesium in the body (8:11 / 5:50) Other vitamins and minerals needed to ensure adequate magnesium levels (9:22 / 7:02) How to stop magnesium depletion (9:33 / 7:10) Magnesium supplements (10:24 / 8:03)

This episode is brought to you by Rupa Health, Cozy Earth, and BiOptimizers. Polycystic ovary syndrome, or PCOS, affects 5 to 10% of women in their childbearing years. Despite the many women struggling with the difficult symptoms of PCOS, we still know little about it. Those symptoms can include irregular or missing periods, excessive hair growth or hair loss, acne, and weight gain. Sadly, the average woman with PCOS sees four doctors before receiving a diagnosis. Today on The Doctor’s Farmacy, I’m excited to talk to Dr. Heather Huddleston to dig into the nuances and research around PCOS. Dr. Huddleston is the founder of the UCSF Multi-disciplinary PCOS Clinic and Research Center. This clinic provides care via an integrated group of providers with expertise in reproductive endocrinology, dermatology, nutrition, and psychology. Through the associated research program, Dr. Huddleston oversees investigations aimed at advancing our understanding of how physical activity, depression, cognition, sleep, and metabolic health all contribute to the manifestations of PCOS. Dr. Huddleston is passionate about broadly improving the care of patients with PCOS and serves as a medical advisor to Allara Health, which is an all-in-one virtual care platform for people with PCOS. This episode is brought to you by Rupa Health, Cozy Earth, and BiOptimizers. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Cozy Earth makes the most comfortable, temperature-regulating, and nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Magnesium Breakthrough really stands out from the other magnesium supplements out there. BiOptimizers is offering my community 10% off, so just head over to magbreakthrough.com/hyman and use code Hyman10. Here are more details from our interview (audio version / Apple Subscriber version): Why PCOS often falls through the cracks in our siloed medical system (6:04 / 3:12) Symptoms of PCOS (7:34 / 4:50) Do we know the causes of PCOS? (9:18 / 6:26) Diet, nutrition, gut health, and PCOS (14:00 / 10:21) How inflammation affects and exacerbates PCOS (17:15 / 14:22) The five areas Dr. Huddleston addresses with PCOS patients (22:54 / 18:20) Therapies for and approaches to treating PCOS (25:29 / 20:45) Supplements for treating PCOS (30:37 / 26:19) How exercise and quality sleep can benefit PCOS patients (33:23 / 28:52) Measuring insulin levels and diagnosing insulin resistance (43:03 / 38:35) Learn more about Dr. Huddleston here. Learn more about Allara at allarahealth.com.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on Meal Planning Tips & Setting Up Your Kitchen for Optimal Health with functional nutritionist, Taylor Groff. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, Paleovalley, and InsideTracker. The most profound cases of healing are in people who refuse to give up. Even if they’ve found some things that improve their condition, they continue searching for new ways to feel better and better. This is how we break down walls in medicine. The Functional Medicine methodology is the same; there is no end to searching for what is underneath the symptoms. Functional Medicine healing protocols can ultimately help change the prognosis of so many conditions, including the autoimmune disease multiple sclerosis. In today’s episode, I talk with Dr. Terry Wahls and Dr. Todd LePine about using diet, meditation, and much more to reverse devastating autoimmune disease symptoms. Dr. Terry Wahls is a clinical professor of medicine at the University of Iowa. Her secondary progressive multiple sclerosis confined her to a tilt-recline wheelchair for four years, but she restored her health using a diet and lifestyle program she designed specifically for mitochondrial health and now pedals her bike to work each day. She is the author of The Wahls Protocol: How I Beat Progressive MS Using Paleo Principles and Functional Medicine, The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles, and the cookbook, The Wahls Protocol Cooking for Life: The Revolutionary Modern Paleo Plan to Treat All Chronic Autoimmune Conditions. Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine certified practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. This episode is brought to you by Rupa Health, Paleovalley, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Full-length episodes of these interviews can be found here: Dr. Terry Wahls Dr. Todd LePine Dr. Terry Wahls

This episode is sponsored by InsideTracker and Athletic Greens. Glutathione is the most important molecule you need to stay healthy and prevent disease—yet you’ve probably never heard of it. It’s the secret to preventing aging, cancer, heart disease, dementia, and more, and it is necessary to treat everything from autism to Alzheimer’s disease. The good news is your body produces its own glutathione. The bad news is poor diet, pollution, toxins, medications, stress, trauma, aging, infections, and radiation all deplete your glutathione levels. In today’s episode of a new series called Health Bites, I discuss what glutathione is, why it’s important, and tips to help you optimize your glutathione levels, improve your detoxification system, and help protect yourself from chronic illness. This episode is sponsored by InsideTracker and Athletic Greens. This Labor Day, InsideTracker will take 26% off their top-selling Ultimate Plan if you’re in the US or Canada. International customers can take $30 off a Blood Results Upload Plan. Just go to insidetracker.com/DrHyman. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What is glutathione? (4:26 / 1:31) Diagnostic testing of glutathione levels (6:08 / 3:16) Why many people have a limited ability to detoxify (6:29 / 4:09) The three main ways glutathione protects against chronic illness (8:38/ 5:46) Foods that support glutathione production (10:53 / 8:00) How exercise boosts glutathione (13:23 / 10:30) Reducing toxic exposure (14:19 / 11:35) Supplementing with N-acetyl-cysteine, alpha lipoic acid, methylation nutrients (folate and vitamins B6 and B12), selenium, antioxidants (including vitamins C and E in the form of mixed tocopherols), and milk thistle to boost glutathione (14:45 / 11:50) Mentioned in this episode Environmental Working Group ewg.org

This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker. All living things are programmed with a certain lifespan, which can be dramatically different from species to species. Humans now, in general, live twice as long as our ancestors, thanks to environmental changes and advances in medicine. But most of us spend the last years of our lives without the quality of life we really want. We’ve come to identify a slew of symptoms and chronic diseases as a natural part of aging, but do they really have to be? Today I’m excited to talk to Dr. George Church all about the latest science on reprogramming our genes to extend our healthspan and lifespan. Dr. George Church is a professor of genetics at Harvard Medical School, a founding member of the Wyss Institute, and director of PersonalGenomes.org, the world’s only open-access information on human genomic, environmental, and trait data. Dr. Church is known for pioneering the fields of personal genomics and synthetic biology. He developed the first methods for the first genome sequence and his team invented CRISPR for human stem cell genome editing and other synthetic biology technologies and applications—including new ways to create organs for transplantation, gene therapies for aging reversal, and gene drives to eliminate Lyme disease and malaria. Dr. Church is the director of IARPA & NIH BRAIN Projects and the National Institutes of Health Center for Excellence in Genomic Science. He is the author of Regenesis. This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): The top things that prevent disease and enhance longevity (7:06 / 4:13) Defining aging as a disease and treating it as such (8:24 / 5:40) Reprogramming and repairing cells to a younger state (12:24 / 9:35) The future, and challenges, of delivering Yamanaka factors for cell reprogramming (15:05 / 11:50) Gene editing vs gene therapy (28:02 / 22:36) Using gene therapy to reverse disease and lengthen life span (34:44 / 30:55) Animal-to-human organ transplants (37:34 / 33:04) Can we live youthfully to 100 years old and beyond? (44:31 / 40:34) How much and what types of protein do we need for healthy aging? (50:30 / 45:50) Using gene editing to bring back mammoths to restore damaged ecosystems (1:00:53 / 56:50) Get a copy of George Church and Ed Regis’ book, Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves, here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, InsideTracker, and Pendulum. The majority of foods on our market shelves contain insane amounts of added sugar. One of the most problematic of these sugars is fructose, which raises our levels of uric acid, a central player in the metabolic mayhem affecting so many of us. This doesn’t mean all foods containing fructose are bad. Like all parts of health and nutrition, there are nuances we need to consider to create optimal health. In today’s episode, I talk with Drs. David Perlmutter, Casey Means, and Richard Johnson about how fructose and uric acid impact our physiology, why measuring uric acid levels is so important, and how fructose impacts our energy. Dr. David Perlmutter is a board-certified neurologist and five-time New York Times bestselling author. He serves on the board of directors and is a Fellow of the American College of Nutrition. He is the author of Grain Brain among others, and his new book, Drop Acid, was just released. Dr. Perlmutter received his MD from the University of Miami School of Medicine, where he was awarded the Leonard G. Rowntree Research Award. Dr. Casey Means is a Stanford-trained physician, Chief Medical Officer, and cofounder of metabolic health company Levels, an associate editor of the International Journal of Disease Reversal and Prevention, and a guest lecturer at Stanford University. Her mission is to maximize human potential and reverse the epidemic of preventable chronic disease by empowering individuals with tools that can facilitate a deep understanding of our bodies and inform personalized and sustainable dietary and lifestyle choices. Dr. Richard Johnson is a professor of medicine at the University of Colorado in Denver and has been a practicing physician and clinical scientist for over 25 years. He is internationally recognized for his seminal work on the role of sugar, and its component fructose, in obesity and diabetes. His work has also suggested a fundamental role for uric acid (which is generated during fructose metabolism) in metabolic syndrome. He previously authored The Sugar Fix with Timothy Gower in 2008, and The Fat Switch in 2012. His new book, Nature Wants Us to Be Fat, was just released. This episode is brought to you by Rupa Health, InsideTracker, and Pendulum. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20. Full-length episodes of these interviews can be found here: Dr. David Perlmutter Dr. Casey Means Dr. Richard Johnson

This episode is sponsored by InsideTracker and Athletic Greens. There are 37 billion chemical reactions happening within your body every second. And every single one of these reactions requires vitamins and minerals to make it work. This is why what you put on your fork is the most important thing you do every day, and it’s why I say food isn’t like medicine—food is medicine. It’s information, and it’s the most powerful drug on the planet. It influences your capacity to live a rich, energetic, connected, soulful life. In today’s episode of a new series called Health Bites, I discuss how to use food as medicine. I share the principles of eating an optimal diet, a list of the foods we should avoid, my number-one food philosophy, and more! This episode is sponsored by InsideTracker and Athletic Greens. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): Why food is the most powerful tool in your medical toolbox (3:44 / 1:38) How food upgrades or downgrades your biological software with every bite (6:46 / 4:50) Nutrigenomics and personalized nutrition (10:01 / 7:47) What is the optimal diet? (13:13 / 11:03) What should we avoid? (17:17 / 15:03) My number-one food philosophy (18:38 / 16:26)

This episode is brought to you by BiOptimizers, InsideTracker, and Pendulum. I’ve always been a big proponent of learning from those who came before us. The knowledge of ancient cultures is one piece of the foundation of modern medicine, but much shamanic wisdom has been ignored and is now being lost. It benefits us to stop and think about what’s going on below the surface, the things we can’t see—for our health, our perception of reality, everything. Invisible bacteria is one example, wisdom is another. Today I am thrilled to talk to my friend Alberto Villoldo about the role of ancient wisdom in health, healing, and aging optimally. Medical anthropologist Alberto Villoldo Ph.D. is an international bestselling author who has researched the shamanic healing practices of the Amazon and Andes for over 25 years. He is the founder of the Four Winds Society, an organization dedicated to the bridging of ancient shamanic traditions with modern medicine and psychology. Dr. Villoldo is the author of numerous books, including Power Up Your Brain; Shaman, Healer, Sage; Mending the Past and Healing the Future with Soul Retrieval; The Four Insights; Courageous Dreaming; One Spirit Medicine, and Grow a New Body. His latest book is The Wisdom Wheel: A Mythic Journey through the Four Directions, which we talk more about in this episode. This episode is brought to you by BiOptimizers, InsideTracker, and Pendulum. BiOptimizers Magnesium Breakthrough formula contains seven different forms of magnesium, all of which have different functions in the body. Go to magbreakthrough.com/hyman and use code hyman10 at checkout for 10% off your next order. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20. Here are more details from our interview (audio version / Apple Subscriber version): What shamans view as our one illness and its one cure (6:08 / 3:24) Differentiating information and wisdom (9:44 / 7:02) How Alberto introduced me to a different way of healing (10:56 / 8:21) What is a shaman? (14:24 / 11:43) Why our brain needs ceremony, ritual, and rites of passage to heal (25:43 / 21:34) Gaining insight into the invisible world (34:05 / 29:54) How to upgrade your brain (38:58 / 34:45) The four animal archetype levels of shamanic healing (45:31 / 41:26) Using plant medicines and psychedelics to heal trauma (52:04 / 47:52) How plant compounds are indispensable to human health and healing (1:02:55 / 59:04) Learn more about Alberto here and get a copy of his new book, The Wisdom Wheel: A Mythic Journey through the Four Directions, here.

This episode is brought to you by Rupa Health, ButcherBox, and Comvita. As you lose muscle, you lose mitochondria and your metabolism slows down. Then there is the fact that the natural loss of muscle mass and strength as we age is associated with all-cause mortality and linked to the incidence of many chronic diseases like cardiovascular disease and stroke, hypertension, insulin resistance, and type 2 diabetes. This is why muscle mass is not only essential for maintaining a healthy weight, but it’s also a key factor in reducing the risk of chronic disease and improving your healthspan and longevity. In this episode, I speak with Drs. Stuart Phillips and Chris Rinsch, Dr. Gabrielle Lyon, and Mark Sisson about the importance of supporting our body’s largest organ, muscle. Dr. Chris Rinsch is co-founder and CEO at Amazentis where he oversees the company’s operations in Switzerland. For more than two decades, he has been an innovator in the life sciences arena. Dr. Stuart Phillips is a Professor in the Department of Kinesiology and a member of the School of Medicine at McMaster University. He is Tier 1 Canada Research Chair in Skeletal Muscle Health. He is also the Director of the McMaster University Physical Activity Centre of Excellence. Dr. Gabrielle Lyon is an integrative physician who completed her fellowship in Nutritional Sciences and Geriatrics at Washington University, St. Louis. She is board-certified in Family Medicine and completed her undergraduate work in Human Nutrition Vitamin and Mineral Metabolism. Mark Sisson is the founder of the popular daily health blog, Mark’s Daily Apple, godfather to the Primal food and lifestyle movement, and the New York Times bestselling author of The Keto Reset Diet. His latest book is Keto for Life, where he discusses how he combines the keto diet with a Primal lifestyle for optimal health and longevity. Mark is the author of numerous other books as well, including The Primal Blueprint. This episode is brought to you by Rupa Health, ButcherBox, and Comvita. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. If you sign up today, ButcherBox will give you two ribeye steaks for free in your first box. Just go to butcherbox.com/farmacy to claim this deal. Learn more about Comvita at comvita.com, and enter code Hyman25 for 25% off all Manuka honey and bee products. (This offer does not apply to bundles or sale items.) Full-length episodes of these interviews can be found here: Dr. Stuart Phillips and Dr. Chris Rinsch Dr. Gabrielle Lyon Mark Sisson

This episode is brought to you by Paleovalley and Athletic Greens. Food should be a tool for helping us feel our best. But most people don’t realize what kind of impact many of the foods they eat are having on their blood sugar—and subsequently their entire body. The symptoms of blood sugar imbalances are everyday occurrences for most people. Feeling hungry even when you just ate, craving sweets, and dealing with acne, hormonal imbalances, and signs of aging, like wrinkles, are just a few of the many symptoms of blood sugar swings. When these continue to go unchecked, more severe dysfunctions can occur, like type 2 diabetes, infertility, fatty liver disease, and dementia. In today’s episode, I talk with Dr. Ben Bikman, Dhru Purohit, and Dr. Ronesh Sinha about how common dietary patterns like eating simple carbs throughout the day create constant insulin spikes leading to insulin resistance, which in turn contributes to many diseases and aging. Dr. Ben Bikman is a renowned metabolic research scientist and a popular speaker on human metabolism and nutrition. Backed by years of research, Dr. Bikman’s mission is to help the world appreciate the prevalence and relevance of insulin resistance. He is the author of the book Why We Get Sick, which offers a thought-provoking yet real solution to insulin resistance and reversing prediabetes, improving brain function, shedding fat, and preventing diabetes. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. Dr. Ronesh Sinha, author of The South Asian Health Solution, is an internal medicine physician who runs a lifestyle clinic in Silicon Valley focused on reversing insulin resistance in ethnically diverse patients. He is also an expert in corporate wellness and serves as the Chief Medical Officer for the Silicon Valley Employer Forum, where he serves as a global advisor to shape health benefits for over 55 major Silicon Valley companies. This episode is brought to you by Paleovalley and Athletic Greens. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Full-length episodes of these interviews can be found here: Dr. Ben Bikman Dhru Purohit Dr. Ronesh Sinha

This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker. Many people think of metabolism as one specific system in the body, when in fact it’s the sum of many different processes that are serving other vital roles for us as well. Our bodies are not closed systems, so our environment, social networks, diet, hormones, microbiome, genetics, and more, all influence how well our metabolism works, or how well we can extract energy from our food. I’m so happy to sit down with my good friend Dr. William Li to talk about what metabolism really means, why the old way of thinking about metabolism hasn’t helped us, and how to make positive impacts on our metabolism at any age. Dr. William Li is a world-renowned physician, scientist, speaker, and author of Eat to Beat Disease - The New Science of How Your Body Can Heal Itself. He is best known for leading the Angiogenesis Foundation. His groundbreaking work has impacted more than 70 diseases, including cancer, diabetes, blindness, heart disease, and obesity. An author of over 100 scientific publications in leading journals such as Science, the New England Journal of Medicine, The Lancet, and more, Dr. Li has served on the faculties of Harvard, Tufts, and Dartmouth Medical School. This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now, get 40% off your Cozy Earth sheets at cozyearth.com and use code MARK40. InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): Shifting away from the idea that eating less and exercising more is the key to weight loss (4:51 / 2:12) How calories affect metabolism (13:14 / 11:25) Research measuring the four phases of metabolism as we age (16:07 / 13:36) What is metabolism? (24:03 / 21:26) Common myths about metabolism (28:35 / 24:37) Supporting the gut microbiome to raise metabolism and promote health (36:18 / 32:03) Foods that mimic caloric restriction (40:27 / 36:10) Our body’s ability to reverse disease (52:59 / 46:21) Reducing stress in a doomscrolling society (54:07 / 49:30) How to restore health to your metabolism (56:03/ 51:56) Mentioned in this episode Perspective: Obesity—an unexplained epidemic Competing paradigms of obesity pathogenesis: energy balance versus carbohydrate-insulin models Daily energy expenditure through the human life course Get a copy of Dr. Li’s book, Eat to Beat Disease: The New Science of How Your Body Can Heal Itself, here and check out his Masterclass with Dr. William Li here.

This episode is brought to you by Rupa Health, Thrive Market, and Comvita. Today, as part of my Masterclass series, I’m answering personal questions my team put together from the “Let’s Get Closer” card deck. I am joined by my good friend and podcast host, Dhru Purohit, to give you a peek into my personal life as I answer questions about my greatest struggles, what I’m addicted to, the best advice I’ve received, and much more. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health, Thrive Market, and Comvita. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Thrive Market is an online membership-based grocery store that makes eating well convenient and more affordable. Join today at thrivemarket.com/hyman to receive an extra $80 worth of free groceries with your first order. Comvita offers the most premium, pure, well-researched, and sustainably sourced Manuka products available on the market today. You can learn more at comvita.com, and enter code Hyman25 for 25% off all Manuka honey and bee products. (This offer does not apply to bundles or sale items.) In this episode, we discuss (audio version / Apple Subscriber version): The last time I asked for help (5:20 / 2:12) A time when I felt the most alive (7:04 / 4:45) The way I like to be comforted when I’m sad or upset (12:00 / 9:38) What I am addicted to (14:08 / 11:47) What I miss about being a kid (21:42 / 18:03) Characteristics I most admire in others (25:06 / 21:26) The greatest struggles I’ve overcome (25:50 / 22:10) The best advice I’ve received (27:57 / 24:18) My biggest fear (30:34 / 26:54) My definition of success (33:14 / 29:37) The most miraculous thing I’ve experienced (34:55 / 31:17) Something I can’t explain (40:55 / 37:15) How I’d like to be remembered (46:28 / 42:50) Mentioned in this episode: Let’s Get Closer by Intelligent Change Inner.U How to Conquer Your Mind to Live Your Best Life with Colin O’Brady The Spontaneous Fulfillment of Desire by Deepak Chopra

This episode is brought to you by ButcherBox and Athletic Greens. Our gut is a powerful control center, due to its bidirectional communication with the brain, which we call the gut-brain axis. This links the emotional and cognitive centers of the brain with intestinal function. Certain conditions, such as irritable bowel syndrome (IBS), are tied to imbalances in the gut-brain axis and can benefit from taking a systems approach in healing, which includes looking at diet, the microbiome, stress management, and more. In today’s episode, I talk with Dr. Todd LePine, Dr. Emeran Mayer, and Dr. George Papanicolaou about various root causes of irritable bowel syndrome, including microbiome imbalance, parasites, and stress. Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine certified practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. Dr. Emeran Mayer is the author of The Gut-Immune Connection as well as The Mind-Gut Connection. He has studied brain-body interactions for the last 40 years, is the executive director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience, and is the founding director of the UCLA Brain Gut Microbiome Center at the University of California at Los Angeles. His research has been supported by the National Institutes of Health for the past 25 years, and he is considered a pioneer and world leader in the area of brain-gut microbiome interactions and its clinical implications.⁣ Dr. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is board certified in Family Medicine from Abington Memorial Hospital. He is also an Institute for Functional Medicine practitioner. He worked on the Navajo reservation for four years at the Chinle Comprehensive Medical Facility, where he served as the Outpatient Department Coordinator. In 2000, he founded Cornerstone Family Practice in Rowley, MA. In 2015, he established Cornerstone Personal Health, a practice dedicated entirely to Functional Medicine. Dr. Papanicolaou joined The UltraWellness Center in 2017. This episode is brought to you by ButcherBox and Athletic Greens. If you sign up today, ButcherBox will give you two ribeye steaks for free in your first box. Just go to butcherbox.com/farmacy to claim this deal. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Full-length episodes of these interviews can be found here: Dr. Todd LePine Dr. Emeran Mayer Dr. George Papanicolaou

This episode is brought to you by Mitopure, InsideTracker, and Rupa Health. The topic of veganism is hotly debated in terms of health and environmental stewardship. But how did the idea that being vegan is the best way to eat for our bodies and the planet develop in the first place? The answer is more complex than you might think. On this episode of The Doctor’s Farmacy, Jayne Buxton challenges the notion that veganism is the cure for disease and climate change and explains how we got here. A British-Canadian, Jayne Buxton is an author of both fiction and non-fiction. She spent fifteen years doing research-intensive work as a management consultant for a major firm before writing her 1998 book, Ending the Mother War: Starting the Workplace Revolution, which explored the entrenched positions and false choices faced by women wanting to combine motherhood with careers. Jayne subsequently spent years working in the field of work-life balance, advising both parents and corporations, before turning to writing full time. Her new book, The Great Plant-Based Con, challenges the dominant narrative about the vegan diet and proposes a compelling new perspective. This episode is brought to you by Mitopure, InsideTracker, and Rupa Health. Get 10% off Mitopure at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Here are more details from our interview (audio version / Apple Subscriber version): The origins of the overarching mythology that veganism is best for human, animal, and planetary health (5:04 / 2:24) How Big Food, Big Agriculture, and Big Pharma benefit from widespread veganism (7:17 / 4:50) Why the movie The Game Changers was a tipping point for Jayne to write her book (10:58 / 8:13) Countries that have banned vegan diets for children (14:55 / 12:07) My experience treating vegan patients (19:01 / 16:07) Frequent health issues that occur from vegan diets (22:50 / 18:08) Navigating the science, and subsequent dietary recommendations, around vegan diets and eating meat (29:54 / 25:27) Building soil health through regenerative agriculture (51:05 / 45:35) Pervasive myths around cows and methane production (55:05 / 50:40) Jayne’s recommendations for how to eat for optimal human, animal, and planetary health (1:03:53 / 59:38) Learn more about Jayne Buxton and her work at thegreatplantbasedcon.com and get her book, The Great Plant-Based Con: Why eating a plants-only diet won't improve your health or save the planet, here.

This episode is brought to you by Rupa Health, Levels, and Pendulum. Today, as part of my Masterclass series, I’m answering questions submitted by my community through the video app HiHo. I am joined by my good friend and podcast host, Dhru Purohit, to discuss back inflammation, intermittent fasting, treating type 2 diabetes with diet, and much more. Find a link below to follow me on HiHo and we may select your question for a future episode! Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health, Levels, and Pendulum. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. By leveraging biosensors like continuous glucose monitors (CGM), Levels provides real-time feedback on how diet and lifestyle choices impact your metabolic health. Learn more about Levels by going to levels.link/HYMAN. Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20. In this episode, we discuss (audio version / Apple Subscriber version): My recent back injury (4:46 / 1:07) Back inflammation and nerve impingement (10:58 / 7:37) Intermittent fasting (12:08 / 8:45) Treating type 2 diabetes with diet (26:17 / 21:25) Healing cystic acne from the inside out (32:43 / 27:55) Changing the food paradigm (37:57 / 32:49) Follow me on HiHo here! Mentioned in this episode: Calorie Restriction with or without Time-Restricted Eating in Weight Loss The Carbohydrate-Insulin Model of Obesity: Beyond ‘Calories In, Calories Out’ The Carbohydrate-Insulin Model: a Physiological Perspective on the Obesity Pandemic Perspective: Obesity—an unexplained epidemic Food Fix

This episode is brought to you by Rupa Health and Athletic Greens. Every day, 80 million Americans are dealing with some form of autoimmune disease, including Hashimoto’s. Hashimoto’s is the leading cause of hypothyroidism (i.e., an underactive thyroid) in the US, and roughly 14 million people are struggling with this diagnosis. The conventional approach to treating it is based almost entirely on suppressing symptoms with drugs. However, with a Functional Medicine approach, there are so many other steps for treating the thyroid. I talk with Dr. George Papanicolaou, Dr. Elizabeth Boham, and Dhru Purohit about why thorough testing is necessary for identifying Hashimoto’s and how lifestyle changes, such as removing gluten, could help to treat this condition. Dr. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is board certified in Family Medicine from Abington Memorial Hospital. He is also an Institute for Functional Medicine practitioner. Upon graduation from his residency he joined the Indian Health Service. He worked on the Navajo reservation for four years at the Chinle Comprehensive Medical Facility, where he served as the Outpatient Department Coordinator. Dr. Papanicolaou joined The UltraWellness Center in 2017. Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Full-length episodes of these interviews can be found here: Dr. George Papanicolaou Dr. Elizabeth Boham Dhru Purohit

This episode is brought to you by InsideTracker, BiOptimizers, and Comvita. Several months ago, I took thirty days to be by myself in a secluded Vermont cabin. I had no phone, no podcasts, no music, no TV, no work, and no company—it was just me and my thoughts. And I can’t tell you how refreshed, recharged, and centered I felt after that trip. It can be incredibly hard spending time alone with your inner self, but it’s always rewarding. That’s what today’s conversation with my good friend Colin O’Brady is all about. Colin is a ten-time world record breaking explorer, New York Times bestselling author, entrepreneur, speaker, and expert on mindset. He is focused on sharing his hard-won wisdom to encourage others to step outside of their comfort zone and unlock their best lives. Colin’s highly publicized expeditions have been seen by millions and his work has been featured by The New York Times, The Tonight Show, BBC, Forbes, and Today. His world-renowned feats include the world’s first solo, unsupported, and fully human-powered crossing of Antarctica, speed records for the Explorers Grand Slam and the Seven Summits, as well as the first human-powered row across Drake Passage. He is a regular speaker at Fortune 100 companies like Nike, Google, and Amazon and top Universities including UPenn, Georgetown, and Johns Hopkins. This episode is brought to you by InsideTracker, BiOptimizers, and Comvita. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Go to magbreakthrough.com/hyman and use code hyman10 at checkout for 10% off your next order of BiOptimizers Magnesium Breakthrough. Learn more about Comvita at comvita.com, and enter code Hyman25 for 25% off all Manuka honey and bee products. Note: Does not apply to bundles or sale items. Here are more details from our interview (audio version / Apple Subscriber version): Colin’s solo crossing of Antarctica (7:44 / 3:27) The personalized nutrition food bars Colin ate on his expedition (9:37 / 6:55) The advice Colin’s wife gave him on the first day of his Antarctica crossing (18:51 / 15:51) How Colin broke out of a period of anxiety and depression (27:24 / 23:53) Conquering your own mind (31:18 / 27:14) The experience that led me to become a doctor (41:34 / 37:18) Facing the feeling of not having enough time (43:50 / 39:31) What Colin fears more than dying (47:35 / 43:22) Becoming unstuck from the zone of comfortable complacency (49:10 / 46:54) The severe burn injury that served as a major turning point in Colin’s life (54:59 / 52:00) Learn more about Colin at colinobrady.com and get a copy of his new book, The 12-Hour Walk: Invest One Day, Conquer Your Mind, and Unlock Your Best Life, here. Get a copy of Colin’s book, The Impossible First: From Fire to Ice―Crossing Antarctica Alone, here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear Part II of a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on treating and preventing osteoporosis with Dr. Elizabeth Board. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, Paleovalley, and Vuori. Today, as part of my Masterclass series, I’m answering questions submitted by my community through the video app HiHo. I am joined by my good friend and podcast host, Dhru Purohit, to discuss a variety of topics including hair loss, supporting your liver, food and pet allergies, and so much more. Find the link below to follow me on HiHo and we may select your question for a future episode! Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health, Paleovalley, and Vuori. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. It’s the perfect time to upgrade your wardrobe! Vuori is offering my community 20% off your first purchase. Just head over to vuori.com/farmacy to claim this deal. In this episode, we discuss (audio version / Apple Subscriber version): Hair loss and your diet (4:07 / 00:57) The best way to support the liver (8:51 / 5:42) Heal alopecia areata by eliminating gluten (19:21 / 14:37) Staying healthy while working long shifts (21:16 / 16:32) The root cause of allergies (26:15 / 21:26) Choosing the right type of fasting for you (32:23 / 27:38) What’s the deal with cheese? (34:37 / 29:48) Healing dry skin from the inside out (39:00 / 34:17) Medication for high blood pressure (41:12 / 36:22) Follow me on HiHo here! Mentioned in this episode: This American Life: As the Worm Turns Betty Body with Dr. Stephanie Estima

This episode is brought to you by Rupa Health and Athletic Greens. Osteoporosis is very common, especially as we age, but it doesn’t have to be the life-threatening risk that currently it is. We’ve been led to believe that getting enough calcium is the key to healthy bones. In truth, your bone health is determined by your diet, gut health and nutrient absorption, physical activity levels, muscle mass, and more. I talk with Dr. Todd LePine, Dr. David Ludwig, and Dhru Purohit about the myths surrounding bone health and why it’s important to take steps to strengthen your bones at every age. Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine certified practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. David S. Ludwig, MD, PhD, is an endocrinologist and researcher at Boston Children’s Hospital. He holds the rank of Professor of Pediatrics at Harvard Medical School and Professor of Nutrition at Harvard School of Public Health. Dr. Ludwig is codirector of the New Balance Foundation Obesity Prevention Center and founder of the Optimal Weight for Life program, one of the country’s oldest and largest clinics for the care of overweight children. For more than 25 years, Dr. Ludwig has studied the effects of dietary composition on metabolism, body weight, and risk for chronic disease. Described as an “obesity warrior” by Time Magazine, Dr. Ludwig has fought for fundamental policy changes to improve the food environment. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Full-length episodes of these interviews can be found here: Dr. Todd LePine Dr. David Ludwig Dhru Purohit

This episode is brought to you by ButcherBox, InsideTracker, and Cozy Earth. The common medical approach to psychiatric disorders is to treat the symptoms. But the truth is that we just don’t know how the biological, psychological, and social risk factors and symptoms of these problems fit together. We don’t know what the underlying pathology is. I was excited to talk to Dr. Christopher Palmer who is disrupting the paradigm of psychiatry, about new ways of treating psychiatric disorders, specifically with the ketogenic diet and mitochondrial repair. Dr. Palmer is a psychiatrist and researcher working at the interface of metabolism and mental health. He is the Director of the Department of Postgraduate and Continuing Education at McLean Hospital and an Assistant Professor of Psychiatry at Harvard Medical School. For over 25 years, he has held leadership roles in psychiatric education, conducted research, and worked with people who have treatment-resistant mental illnesses. He has been pioneering the use of the medical ketogenic diet in the treatment of psychiatric disorders—conducting research, treating patients, writing, and speaking around the world on this topic. This episode is brought to you by ButcherBox, InsideTracker, and Cozy Earth. Sign up today and get two ribeye steaks for free in your first ButcherBox. Just go to butcherbox.com/farmacy. InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Here are more details from our interview (audio version / Apple Subscriber version): Why mental illness happens and is so hard to treat (6:33 / 3:51) The patient who changed the way Dr. Palmer treats mental illness (11:06 / 8:08) The ketogenic diet as a treatment for epilepsy, seizure disorders, and mental health disorders (17:03 / 14:09) Getting to the root cause of inflammation in the brain (20:16 / 17:26) Viewing mental disorders as metabolic disorders of the brain (27:37 / 23:20) Mitochondrial energy deficits in children with autism (34:28 / 30:03) Improve mitochondrial function (35:14 / 31:20) Addressing inflammation in the body (42:16 / 38:00) Validating a multifaceted approach to treating mental health disorders (47:55 / 44:39) Dr. Palmer’s experience treating a child with ADHD (57:23 / 52:52) Children with high levels of insulin resistance and associated risk for schizophrenia, bipolar disorder, and depression (59:05 / 54:42) Referenced in this episode: Before & after handwriting from Dr. Hyman’s patient Learn more about Dr. Palmer here. Get his book, Brain Energy: A Revolutionary Breakthrough in Understanding Mental Health—and Improving Treatment for Anxiety, Depression, OCD, PTSD, and More, here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health and InsideTracker. Today, as part of my Masterclass series, I’m answering questions submitted by my community through the video app HiHo. I am joined by my good friend and podcast host, Dhru Purohit to discuss the role of the gut microbiome in OCD, my approach to treating Lyme disease, the best ways to detox, and much more. Find a link below to follow me on HiHo and we may select your question for a future episode! Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. In this episode, we discuss (audio version / Apple Subscriber version): OCD and its connection to the gut (3:24 / 00:52) Treating persistent Lyme disease (12:02 / 9:38) Addressing ringing in the ear, or tinnitus (25:46 / 23:18) Ways to detox the body (27:55 / 25:28) The whole body approach to treating lupus (33:47 / 31:21) Follow me on HiHo here! Mentioned in this episode: Gut Food IFM Find a Functional Medicine Practitioner Find a Trained Ozone Therapy Practitioner

This episode is brought to you by Athletic Greens and Paleovalley. If there was something you could do every day to boost your focus and productivity, feel energized, reduce stress, sleep better, maintain a positive outlook, and support whole-body health, wouldn’t you do it? It’s for all these reasons, and more, that meditation is a foundational pillar to good health. In today’s episode, I talk with Daniel Goleman, Emily Fletcher, and Dr. Joe Dispenza about how meditation changes lives by reducing stress, creating resilience, and improving emotional intelligence. Daniel Goleman is best known for his worldwide bestseller Emotional Intelligence and most recently coauthored the book Altered Traits: Science Reveals How Meditation Changes Your Mind, Brain, and Body. Goleman has been ranked among the 25 most influential business leaders by several business publications including Time and the Wall Street Journal. Apart from his writing on emotional intelligence, Goleman has written books on topics including self-deception, creativity, transparency, meditation, social and emotional learning, eco-literacy, and the ecological crisis. Emily Fletcher is the founder of Ziva, the creator of The Ziva Technique, and a leading expert in meditation for high performers. She is also the author of Stress Less, Accomplish More. Dr. Joe Dispenza’s passion can be found at the intersection of the latest findings from the fields of neuroscience, epigenetics, and quantum physics to explore the science behind spontaneous remissions. He uses that knowledge to teach people how to heal their bodies of health conditions, make significant changes in their lives, and evolve their consciousness. Since 2010, he has partnered with scientists and universities to perform extensive research on the effects that meditation has on the brain and body. He and his team have also studied gene expression, protein regulation, immune response, neurotransmitter changes, telomere length, and variations in bioactive cellular metabolic particles in novice and advanced meditators. This episode is brought to you by Athletic Greens and Paleovalley. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Full-length episodes of these interviews can be found here: Daniel Goleman Emily Fletcher Dr. Joe Dispenza

This episode is brought to you by BiOptimizers, Rupa Health, and Pendulum. What’s the point in living a long time? Being fully in contribution to life. I want to do that feeling healthy and vital, not sick and decrepit. Everything we do speaks to our genes—the food we eat, our relationships, our environment. You’re either telling your genes to age faster or age slower. So I’m constantly working on how to give my genes the right information to do the latter. Today’s podcast episode was recorded on my recent trip to Antarctica with my own doctor, Dr. Matt Cook. He’s helped me heal and has integrated so many different forms of technologies and science to rebuild people’s health from the ground up. Dr. Cook is the Founder of BioReset® Medical. He is a board-certified anesthesiologist with over 20 years of experience practicing medicine, focusing the last 14 years on Functional and Regenerative Medicine. He graduated from the University of Washington School of Medicine, completed his anesthesiology residency at the University of California San Francisco (UCSF), and completed a fellowship in Functional Medicine. This episode is brought to you by BiOptimizers, Rupa Health, and Pendulum. BiOptimizers Magnesium Breakthrough formula contains seven different forms of magnesium, all of which have different functions in the body. There is truly nothing like it on the market. Go to magbreakthrough.com/hyman and use code hyman10 at checkout for 10% off your next order. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20. Here are more details from our interview (audio version / Apple Subscriber version): What’s the point of living a long life? (5:38 / 2:23) What I learned from my travel through the Blue Zones (6:36 / 3:25) Five converging trends that will change our thinking about medicine and health (13:33 / 10:16) The root causes of aging (18:16 / 15:02) Influence your genes to reverse your biological age (22:29 / 17:42) How to eat to extend your life span (28:40 / 24:01) Practices and supplements to support healthy aging (35:51 / 31:23) Regenerative medicine therapies and protocols (48:12 / 42:13) What the Yamanaka factors teach us about aging (1:13:12 / 1:08:31) Reimaging how we deal with trauma (1:21:21 / 1:16:49) Learn more about Dr. Matt Cook and his work at BioReset Medical at bioresetmedical.com.

This episode is brought to you by Rupa Health, Thrive Market, and InsideTracker. Today, as part of my Masterclass series, I’m answering questions submitted by my community through the video app HiHo. I am joined by my good friend and podcast host, Dhru Purohit, to discuss how to reduce your biological age, what to do if you have a low sex drive, the Functional Medicine approach to treating osteoporosis, and much more. Find a link below to follow me on HiHo and we may select your question for a future episode! Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health, Thrive Market, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Thrive Market is an online membership-based grocery store that makes eating well convenient and more affordable. Join today at thrivemarket.com/hyman to receive an extra $80 of free groceries with your first order. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. In this episode, we discuss (audio version / Apple Subscriber version): What do high homocysteine levels mean? (3:44 / 00:52) Tips to reduce our biological age (17:23 / 13:42) The connection between grip strength, muscle loss, and aging (23:15 / 18:46) Causes of low sex drive and how to correct them (28:19 / 23:42) The root cause and treatment for PCOS (32:44 / 28:04) The Functional Medicine approach to osteoporosis and increasing bone density (37:47 / 33:42) Follow me on HiHo here! Mentioned in this episode: True Diagnostics Nordic Labs Why Muscle Is the Key to Longevity with Dr. Gabrielle Lyon Are We Eating Too Much (Or Not Enough) Protein for Good Health with Dr. Gabrielle Lyon