The Dr. Hyman Show

This episode is brought to you by Rupa Health, ButcherBox, and Mitopure. Sleep is a keystone of health. Most people know they should get more high-quality sleep, but they don’t really know where to start. But understanding the way our brain and neurotransmitters work means we can hack our sleep to not just feel amazing but to level up our focus, skills, and knowledge. And it’s not all about what happens at night, either—getting the right exposure to light at the right times has a profound impact on our circadian rhythms and the way our bodies transition to sleep. In today’s episode, I talk with Dr. Roger Seheult, Dhru Purohit, and Dr. Andrew Huberman about why optimizing your sleep should be prioritized and how you can get better sleep. Dr. Roger Seheult is currently an associate clinical professor at the University of California, Riverside School of Medicine, and an assistant clinical professor at the School of Medicine and Allied Health at Loma Linda University. Dr. Seheult is quadruple board certified in Internal Medicine, Pulmonary Diseases, Critical Care Medicine, and Sleep Medicine through the American Board of Internal Medicine. He is also the cofounder of MedCram, an online medical education company that helps healthcare professionals and laypeople understand medical topics clearly. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. Dr. Andrew Huberman is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award in 2017, which is given to the scientist making the largest discoveries in the study of vision. His lab’s most recent work focuses on the influence of vision and respiration on human performance and brain states such as fear and courage. Work from the Huberman Laboratory at Stanford University School of Medicine has been published in top journals including Nature, Science, and Cell and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets. This episode is brought to you by Rupa Health, ButcherBox, and Mitopure. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. If you sign up at butcherbox.com/farmacy, ButcherBox will give you 2lbs of ground beef free for one whole year. Get 10% off at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Full-length episodes of these interviews can be found here: Dr. Roger Seheult Dhru Purohit Dr. Andrew Huberman

This episode is sponsored by InsideTracker and Athletic Greens. Believe it or not, the surface area of your small intestine, which is where your food is absorbed, is the size of a tennis court. Your small intestine is also the home of your gut-immune system, which accounts for about 60 percent of your total immune system. The lining of this sophisticated system is just one cell layer away from a toxic sewer where all of the bacteria and undigested food particles live in your gut. If that lining breaks down—from stress; too many antibiotics or anti-inflammatory drugs like aspirin or ibuprofen; steroids; intestinal infections; a low-fiber, high-sugar diet; alcohol; and more—your immune system will be exposed to foreign particles from food, bacteria, and other microbes. This, in turn, creates havoc that can lead to an irritable bowel and other system-wide problems including allergies, arthritis, and autoimmune and mood disorders. In today’s episode of a new series called Health Bites, I discuss how to heal irritable bowel syndrome (IBS) and upregulate your gut health, which is at the forefront of Americans’ most common health complaints. This episode is sponsored by InsideTracker and Athletic Greens. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What is irritable bowel syndrome? (4:05 / 1:12) Symptoms of IBS (4:30 / 1:35) Causes of IBS (4:54 / 2:00) Identifying food allergies as the potential cause of IBS (8:00 / 5:11) How gut imbalance leads to IBS (9:36 / 6:44) Diagnostic testing to access gut health (12:14 / 9:25) What is SIBO, how does it cause IBS, and how is it diagnosed? (15:20 / 12:29) Assessing if yeast overgrowth is causing your gut issues (15:58 / 13:05) Treating yeast overgrowth and SIBO (16:40 / 13:50) Strategies for rebooting the gut and restoring optimal gut health (17:44 / 14:55)

This episode is brought to you by Rupa Health, InsideTracker, and FOND Bone Broth. Why are we seeing more chronic disease, stress, obesity, addiction, and so many other states of illness than ever before, despite having the most advanced medical system in the world? Because we aren’t living in a natural and normal world. We’re actually having normal responses to our abnormal circumstances, many of which create trauma that gets stored in the brain and body. Today on The Doctor’s Farmacy, I’m honored to talk to my dear friend Dr. Gabor Maté about the myth of normal, and why doing the difficult work of uncovering trauma is essential for living our fullest expression of life. A renowned speaker and bestselling author, Dr. Gabor Maté is highly sought after for his expertise on a range of topics including addiction, stress, and childhood development. Dr. Maté has written several bestselling books, including the award-winning In the Realm of Hungry Ghosts: Close Encounters with Addiction, When the Body Says No: Exploring the Stress-Disease Connection, and Scattered: How Attention Deficit Disorder Originates and What You Can Do About It, and has co-authored Hold On to Your Kids: Why Parents Need to Matter More Than Peers. His latest book, The Myth of Normal: Trauma, Illness & Healing in a Toxic Culture was just released. This episode is brought to you by Rupa Health, InsideTracker, and FOND Bone Broth. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. To experience the amazing health benefits of FOND Bone Broth, go to fondbonebroth.com/drhyman and use code HYMAN20 to get 20% off your purchase. Here are more details from our interview (audio version / Apple Subscriber version): Uncovering my personal trauma history (6:42 / 3:50) Scientific evidence linking trauma and stress to physical and mental illness (14:38 / 11:45) Social determinants of health (16:34 / 14:15) Our crisis of separation, disconnection, and loneliness (20:25 / 18:00) The link between addiction, our profit-driven culture, and trauma (25:16 / 22:20) The myth of normal (31:07 / 26:33) Tools, therapies, and resources for your own healing (49:50 / 45:41) Treating trauma with plant medicines and psychedelics (55:40 / 51:16) The biology of psychology (1:10:46 / 1:06:20) Gabor’s vision for our society (1:31:42 / 1:25:48) Learn more about Gabor Maté at drgabormate.com and get a copy of his new book, The Myth of Normal—Trauma, Illness, & Healing In a Toxic Culture, here.

This episode is brought to you by Rupa Health, Thrive Market, and Levels. We’ve been told that cognitive decline is inevitable, but researchers are discovering that we have more power over our aging brains than we once thought. What we eat, what we think, and how we live have incredible influence over the health of our brains—and our entire bodies. In today’s episode, I talk with Max Lugavere, Dr. Christopher Palmer, and Dr. Daniel Amen about foods that improve brain health, the link between our metabolic health and brain health, choosing happiness, and so much more. Max Lugavere is a health and science journalist and the author of the New York Times bestselling book Genius Foods: Become Smarter, Happier, and More Productive While Protecting Your Brain for Life, now published in 10 languages around the globe. His sophomore book, also a bestseller, is called The Genius Life: Heal Your Mind, Strengthen Your Body, and Become Extraordinary. Max is the host of a number-one iTunes health and wellness podcast called The Genius Life. Dr. Christopher Palmer is a psychiatrist and researcher working at the intersection of metabolism and mental health. He is the Director of the Department of Postgraduate and Continuing Education at McLean Hospital and an assistant professor of Psychiatry at Harvard Medical School. For over 25 years, he has held leadership roles in psychiatric education, conducted research, and worked with people who have treatment-resistant mental illnesses. He has been pioneering the use of the medical ketogenic diet in the treatment of psychiatric disorders—conducting research, treating patients, writing, and speaking around the world on this topic. Dr. Daniel Amen is a physician, double board-certified psychiatrist, twelve-time New York Times bestselling author, and founder and CEO of Amen Clinics, with 10 US locations. Dr. Amen is the author of many books including the mega-bestseller Change Your Brain, Change Your Life, as well as The End of Mental Illness, Memory Rescue, Healing ADD, and Your Brain Is Always Listening. His new book, You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type, is now available. This episode is brought to you by Rupa Health, Thrive Market, and Levels. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. Join Thrive Market today at thrivemarket.com/hyman to receive an extra $80 in free groceries with your first order. Learn more about Levels by going to levels.link/HYMAN. Full-length episodes of these interviews can be found here: Max Lugavere Dr. Christopher Palmer Dr. Daniel Amen

This episode is sponsored by ButcherBox and Athletic Greens. Think of magnesium as the relaxation mineral. Anything that is tight, irritable, crampy, and stiff—whether it is a body part or even a mood—can be a sign of magnesium deficiency. This critical mineral is actually responsible for over 600 enzyme reactions and is found in all of your tissues—but mainly in your bones, muscles, and brain. You must have it for your cells to make energy, for many different chemical pumps to work, to stabilize membranes, and to help muscles relax. Yet, so many of us are deficient in this important mineral. In today’s episode of a new series called Health Bites, I discuss why magnesium deficiency is a huge problem, why most of us are deficient, how to identify if you are magnesium deficient, and what to do about it. This episode is sponsored by ButcherBox and Athletic Greens. ButcherBox makes it easy to get humanely raised meat and wild-caught, sustainable seafood by delivering it right to your doorstep. If you sign up at butcherbox.com/farmacy, ButcherBox will give you two pounds of ground beef free for one whole year. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 free travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): Why magnesium deficiency is so prevalent (3:26 / 00:57) Signs of magnesium deficiency (4:11 / 1:48) Magnesium use in a traditional hospital setting (5:37 / 3:15) Testing your magnesium levels (7:26 / 5:02) Food sources of magnesium (7:51 / 5:27) Things that deplete magnesium in the body (8:11 / 5:50) Other vitamins and minerals needed to ensure adequate magnesium levels (9:22 / 7:02) How to stop magnesium depletion (9:33 / 7:10) Magnesium supplements (10:24 / 8:03)

This episode is brought to you by Rupa Health, Cozy Earth, and BiOptimizers. Polycystic ovary syndrome, or PCOS, affects 5 to 10% of women in their childbearing years. Despite the many women struggling with the difficult symptoms of PCOS, we still know little about it. Those symptoms can include irregular or missing periods, excessive hair growth or hair loss, acne, and weight gain. Sadly, the average woman with PCOS sees four doctors before receiving a diagnosis. Today on The Doctor’s Farmacy, I’m excited to talk to Dr. Heather Huddleston to dig into the nuances and research around PCOS. Dr. Huddleston is the founder of the UCSF Multi-disciplinary PCOS Clinic and Research Center. This clinic provides care via an integrated group of providers with expertise in reproductive endocrinology, dermatology, nutrition, and psychology. Through the associated research program, Dr. Huddleston oversees investigations aimed at advancing our understanding of how physical activity, depression, cognition, sleep, and metabolic health all contribute to the manifestations of PCOS. Dr. Huddleston is passionate about broadly improving the care of patients with PCOS and serves as a medical advisor to Allara Health, which is an all-in-one virtual care platform for people with PCOS. This episode is brought to you by Rupa Health, Cozy Earth, and BiOptimizers. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Cozy Earth makes the most comfortable, temperature-regulating, and nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Magnesium Breakthrough really stands out from the other magnesium supplements out there. BiOptimizers is offering my community 10% off, so just head over to magbreakthrough.com/hyman and use code Hyman10. Here are more details from our interview (audio version / Apple Subscriber version): Why PCOS often falls through the cracks in our siloed medical system (6:04 / 3:12) Symptoms of PCOS (7:34 / 4:50) Do we know the causes of PCOS? (9:18 / 6:26) Diet, nutrition, gut health, and PCOS (14:00 / 10:21) How inflammation affects and exacerbates PCOS (17:15 / 14:22) The five areas Dr. Huddleston addresses with PCOS patients (22:54 / 18:20) Therapies for and approaches to treating PCOS (25:29 / 20:45) Supplements for treating PCOS (30:37 / 26:19) How exercise and quality sleep can benefit PCOS patients (33:23 / 28:52) Measuring insulin levels and diagnosing insulin resistance (43:03 / 38:35) Learn more about Dr. Huddleston here. Learn more about Allara at allarahealth.com.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on Meal Planning Tips & Setting Up Your Kitchen for Optimal Health with functional nutritionist, Taylor Groff. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, Paleovalley, and InsideTracker. The most profound cases of healing are in people who refuse to give up. Even if they’ve found some things that improve their condition, they continue searching for new ways to feel better and better. This is how we break down walls in medicine. The Functional Medicine methodology is the same; there is no end to searching for what is underneath the symptoms. Functional Medicine healing protocols can ultimately help change the prognosis of so many conditions, including the autoimmune disease multiple sclerosis. In today’s episode, I talk with Dr. Terry Wahls and Dr. Todd LePine about using diet, meditation, and much more to reverse devastating autoimmune disease symptoms. Dr. Terry Wahls is a clinical professor of medicine at the University of Iowa. Her secondary progressive multiple sclerosis confined her to a tilt-recline wheelchair for four years, but she restored her health using a diet and lifestyle program she designed specifically for mitochondrial health and now pedals her bike to work each day. She is the author of The Wahls Protocol: How I Beat Progressive MS Using Paleo Principles and Functional Medicine, The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles, and the cookbook, The Wahls Protocol Cooking for Life: The Revolutionary Modern Paleo Plan to Treat All Chronic Autoimmune Conditions. Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine certified practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. This episode is brought to you by Rupa Health, Paleovalley, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Full-length episodes of these interviews can be found here: Dr. Terry Wahls Dr. Todd LePine Dr. Terry Wahls

This episode is sponsored by InsideTracker and Athletic Greens. Glutathione is the most important molecule you need to stay healthy and prevent disease—yet you’ve probably never heard of it. It’s the secret to preventing aging, cancer, heart disease, dementia, and more, and it is necessary to treat everything from autism to Alzheimer’s disease. The good news is your body produces its own glutathione. The bad news is poor diet, pollution, toxins, medications, stress, trauma, aging, infections, and radiation all deplete your glutathione levels. In today’s episode of a new series called Health Bites, I discuss what glutathione is, why it’s important, and tips to help you optimize your glutathione levels, improve your detoxification system, and help protect yourself from chronic illness. This episode is sponsored by InsideTracker and Athletic Greens. This Labor Day, InsideTracker will take 26% off their top-selling Ultimate Plan if you’re in the US or Canada. International customers can take $30 off a Blood Results Upload Plan. Just go to insidetracker.com/DrHyman. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What is glutathione? (4:26 / 1:31) Diagnostic testing of glutathione levels (6:08 / 3:16) Why many people have a limited ability to detoxify (6:29 / 4:09) The three main ways glutathione protects against chronic illness (8:38/ 5:46) Foods that support glutathione production (10:53 / 8:00) How exercise boosts glutathione (13:23 / 10:30) Reducing toxic exposure (14:19 / 11:35) Supplementing with N-acetyl-cysteine, alpha lipoic acid, methylation nutrients (folate and vitamins B6 and B12), selenium, antioxidants (including vitamins C and E in the form of mixed tocopherols), and milk thistle to boost glutathione (14:45 / 11:50) Mentioned in this episode Environmental Working Group ewg.org

This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker. All living things are programmed with a certain lifespan, which can be dramatically different from species to species. Humans now, in general, live twice as long as our ancestors, thanks to environmental changes and advances in medicine. But most of us spend the last years of our lives without the quality of life we really want. We’ve come to identify a slew of symptoms and chronic diseases as a natural part of aging, but do they really have to be? Today I’m excited to talk to Dr. George Church all about the latest science on reprogramming our genes to extend our healthspan and lifespan. Dr. George Church is a professor of genetics at Harvard Medical School, a founding member of the Wyss Institute, and director of PersonalGenomes.org, the world’s only open-access information on human genomic, environmental, and trait data. Dr. Church is known for pioneering the fields of personal genomics and synthetic biology. He developed the first methods for the first genome sequence and his team invented CRISPR for human stem cell genome editing and other synthetic biology technologies and applications—including new ways to create organs for transplantation, gene therapies for aging reversal, and gene drives to eliminate Lyme disease and malaria. Dr. Church is the director of IARPA & NIH BRAIN Projects and the National Institutes of Health Center for Excellence in Genomic Science. He is the author of Regenesis. This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): The top things that prevent disease and enhance longevity (7:06 / 4:13) Defining aging as a disease and treating it as such (8:24 / 5:40) Reprogramming and repairing cells to a younger state (12:24 / 9:35) The future, and challenges, of delivering Yamanaka factors for cell reprogramming (15:05 / 11:50) Gene editing vs gene therapy (28:02 / 22:36) Using gene therapy to reverse disease and lengthen life span (34:44 / 30:55) Animal-to-human organ transplants (37:34 / 33:04) Can we live youthfully to 100 years old and beyond? (44:31 / 40:34) How much and what types of protein do we need for healthy aging? (50:30 / 45:50) Using gene editing to bring back mammoths to restore damaged ecosystems (1:00:53 / 56:50) Get a copy of George Church and Ed Regis’ book, Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves, here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, InsideTracker, and Pendulum. The majority of foods on our market shelves contain insane amounts of added sugar. One of the most problematic of these sugars is fructose, which raises our levels of uric acid, a central player in the metabolic mayhem affecting so many of us. This doesn’t mean all foods containing fructose are bad. Like all parts of health and nutrition, there are nuances we need to consider to create optimal health. In today’s episode, I talk with Drs. David Perlmutter, Casey Means, and Richard Johnson about how fructose and uric acid impact our physiology, why measuring uric acid levels is so important, and how fructose impacts our energy. Dr. David Perlmutter is a board-certified neurologist and five-time New York Times bestselling author. He serves on the board of directors and is a Fellow of the American College of Nutrition. He is the author of Grain Brain among others, and his new book, Drop Acid, was just released. Dr. Perlmutter received his MD from the University of Miami School of Medicine, where he was awarded the Leonard G. Rowntree Research Award. Dr. Casey Means is a Stanford-trained physician, Chief Medical Officer, and cofounder of metabolic health company Levels, an associate editor of the International Journal of Disease Reversal and Prevention, and a guest lecturer at Stanford University. Her mission is to maximize human potential and reverse the epidemic of preventable chronic disease by empowering individuals with tools that can facilitate a deep understanding of our bodies and inform personalized and sustainable dietary and lifestyle choices. Dr. Richard Johnson is a professor of medicine at the University of Colorado in Denver and has been a practicing physician and clinical scientist for over 25 years. He is internationally recognized for his seminal work on the role of sugar, and its component fructose, in obesity and diabetes. His work has also suggested a fundamental role for uric acid (which is generated during fructose metabolism) in metabolic syndrome. He previously authored The Sugar Fix with Timothy Gower in 2008, and The Fat Switch in 2012. His new book, Nature Wants Us to Be Fat, was just released. This episode is brought to you by Rupa Health, InsideTracker, and Pendulum. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20. Full-length episodes of these interviews can be found here: Dr. David Perlmutter Dr. Casey Means Dr. Richard Johnson

This episode is sponsored by InsideTracker and Athletic Greens. There are 37 billion chemical reactions happening within your body every second. And every single one of these reactions requires vitamins and minerals to make it work. This is why what you put on your fork is the most important thing you do every day, and it’s why I say food isn’t like medicine—food is medicine. It’s information, and it’s the most powerful drug on the planet. It influences your capacity to live a rich, energetic, connected, soulful life. In today’s episode of a new series called Health Bites, I discuss how to use food as medicine. I share the principles of eating an optimal diet, a list of the foods we should avoid, my number-one food philosophy, and more! This episode is sponsored by InsideTracker and Athletic Greens. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): Why food is the most powerful tool in your medical toolbox (3:44 / 1:38) How food upgrades or downgrades your biological software with every bite (6:46 / 4:50) Nutrigenomics and personalized nutrition (10:01 / 7:47) What is the optimal diet? (13:13 / 11:03) What should we avoid? (17:17 / 15:03) My number-one food philosophy (18:38 / 16:26)

This episode is brought to you by BiOptimizers, InsideTracker, and Pendulum. I’ve always been a big proponent of learning from those who came before us. The knowledge of ancient cultures is one piece of the foundation of modern medicine, but much shamanic wisdom has been ignored and is now being lost. It benefits us to stop and think about what’s going on below the surface, the things we can’t see—for our health, our perception of reality, everything. Invisible bacteria is one example, wisdom is another. Today I am thrilled to talk to my friend Alberto Villoldo about the role of ancient wisdom in health, healing, and aging optimally. Medical anthropologist Alberto Villoldo Ph.D. is an international bestselling author who has researched the shamanic healing practices of the Amazon and Andes for over 25 years. He is the founder of the Four Winds Society, an organization dedicated to the bridging of ancient shamanic traditions with modern medicine and psychology. Dr. Villoldo is the author of numerous books, including Power Up Your Brain; Shaman, Healer, Sage; Mending the Past and Healing the Future with Soul Retrieval; The Four Insights; Courageous Dreaming; One Spirit Medicine, and Grow a New Body. His latest book is The Wisdom Wheel: A Mythic Journey through the Four Directions, which we talk more about in this episode. This episode is brought to you by BiOptimizers, InsideTracker, and Pendulum. BiOptimizers Magnesium Breakthrough formula contains seven different forms of magnesium, all of which have different functions in the body. Go to magbreakthrough.com/hyman and use code hyman10 at checkout for 10% off your next order. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20. Here are more details from our interview (audio version / Apple Subscriber version): What shamans view as our one illness and its one cure (6:08 / 3:24) Differentiating information and wisdom (9:44 / 7:02) How Alberto introduced me to a different way of healing (10:56 / 8:21) What is a shaman? (14:24 / 11:43) Why our brain needs ceremony, ritual, and rites of passage to heal (25:43 / 21:34) Gaining insight into the invisible world (34:05 / 29:54) How to upgrade your brain (38:58 / 34:45) The four animal archetype levels of shamanic healing (45:31 / 41:26) Using plant medicines and psychedelics to heal trauma (52:04 / 47:52) How plant compounds are indispensable to human health and healing (1:02:55 / 59:04) Learn more about Alberto here and get a copy of his new book, The Wisdom Wheel: A Mythic Journey through the Four Directions, here.

This episode is brought to you by Rupa Health, ButcherBox, and Comvita. As you lose muscle, you lose mitochondria and your metabolism slows down. Then there is the fact that the natural loss of muscle mass and strength as we age is associated with all-cause mortality and linked to the incidence of many chronic diseases like cardiovascular disease and stroke, hypertension, insulin resistance, and type 2 diabetes. This is why muscle mass is not only essential for maintaining a healthy weight, but it’s also a key factor in reducing the risk of chronic disease and improving your healthspan and longevity. In this episode, I speak with Drs. Stuart Phillips and Chris Rinsch, Dr. Gabrielle Lyon, and Mark Sisson about the importance of supporting our body’s largest organ, muscle. Dr. Chris Rinsch is co-founder and CEO at Amazentis where he oversees the company’s operations in Switzerland. For more than two decades, he has been an innovator in the life sciences arena. Dr. Stuart Phillips is a Professor in the Department of Kinesiology and a member of the School of Medicine at McMaster University. He is Tier 1 Canada Research Chair in Skeletal Muscle Health. He is also the Director of the McMaster University Physical Activity Centre of Excellence. Dr. Gabrielle Lyon is an integrative physician who completed her fellowship in Nutritional Sciences and Geriatrics at Washington University, St. Louis. She is board-certified in Family Medicine and completed her undergraduate work in Human Nutrition Vitamin and Mineral Metabolism. Mark Sisson is the founder of the popular daily health blog, Mark’s Daily Apple, godfather to the Primal food and lifestyle movement, and the New York Times bestselling author of The Keto Reset Diet. His latest book is Keto for Life, where he discusses how he combines the keto diet with a Primal lifestyle for optimal health and longevity. Mark is the author of numerous other books as well, including The Primal Blueprint. This episode is brought to you by Rupa Health, ButcherBox, and Comvita. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. If you sign up today, ButcherBox will give you two ribeye steaks for free in your first box. Just go to butcherbox.com/farmacy to claim this deal. Learn more about Comvita at comvita.com, and enter code Hyman25 for 25% off all Manuka honey and bee products. (This offer does not apply to bundles or sale items.) Full-length episodes of these interviews can be found here: Dr. Stuart Phillips and Dr. Chris Rinsch Dr. Gabrielle Lyon Mark Sisson

This episode is brought to you by Paleovalley and Athletic Greens. Food should be a tool for helping us feel our best. But most people don’t realize what kind of impact many of the foods they eat are having on their blood sugar—and subsequently their entire body. The symptoms of blood sugar imbalances are everyday occurrences for most people. Feeling hungry even when you just ate, craving sweets, and dealing with acne, hormonal imbalances, and signs of aging, like wrinkles, are just a few of the many symptoms of blood sugar swings. When these continue to go unchecked, more severe dysfunctions can occur, like type 2 diabetes, infertility, fatty liver disease, and dementia. In today’s episode, I talk with Dr. Ben Bikman, Dhru Purohit, and Dr. Ronesh Sinha about how common dietary patterns like eating simple carbs throughout the day create constant insulin spikes leading to insulin resistance, which in turn contributes to many diseases and aging. Dr. Ben Bikman is a renowned metabolic research scientist and a popular speaker on human metabolism and nutrition. Backed by years of research, Dr. Bikman’s mission is to help the world appreciate the prevalence and relevance of insulin resistance. He is the author of the book Why We Get Sick, which offers a thought-provoking yet real solution to insulin resistance and reversing prediabetes, improving brain function, shedding fat, and preventing diabetes. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. Dr. Ronesh Sinha, author of The South Asian Health Solution, is an internal medicine physician who runs a lifestyle clinic in Silicon Valley focused on reversing insulin resistance in ethnically diverse patients. He is also an expert in corporate wellness and serves as the Chief Medical Officer for the Silicon Valley Employer Forum, where he serves as a global advisor to shape health benefits for over 55 major Silicon Valley companies. This episode is brought to you by Paleovalley and Athletic Greens. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Full-length episodes of these interviews can be found here: Dr. Ben Bikman Dhru Purohit Dr. Ronesh Sinha

This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker. Many people think of metabolism as one specific system in the body, when in fact it’s the sum of many different processes that are serving other vital roles for us as well. Our bodies are not closed systems, so our environment, social networks, diet, hormones, microbiome, genetics, and more, all influence how well our metabolism works, or how well we can extract energy from our food. I’m so happy to sit down with my good friend Dr. William Li to talk about what metabolism really means, why the old way of thinking about metabolism hasn’t helped us, and how to make positive impacts on our metabolism at any age. Dr. William Li is a world-renowned physician, scientist, speaker, and author of Eat to Beat Disease - The New Science of How Your Body Can Heal Itself. He is best known for leading the Angiogenesis Foundation. His groundbreaking work has impacted more than 70 diseases, including cancer, diabetes, blindness, heart disease, and obesity. An author of over 100 scientific publications in leading journals such as Science, the New England Journal of Medicine, The Lancet, and more, Dr. Li has served on the faculties of Harvard, Tufts, and Dartmouth Medical School. This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now, get 40% off your Cozy Earth sheets at cozyearth.com and use code MARK40. InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): Shifting away from the idea that eating less and exercising more is the key to weight loss (4:51 / 2:12) How calories affect metabolism (13:14 / 11:25) Research measuring the four phases of metabolism as we age (16:07 / 13:36) What is metabolism? (24:03 / 21:26) Common myths about metabolism (28:35 / 24:37) Supporting the gut microbiome to raise metabolism and promote health (36:18 / 32:03) Foods that mimic caloric restriction (40:27 / 36:10) Our body’s ability to reverse disease (52:59 / 46:21) Reducing stress in a doomscrolling society (54:07 / 49:30) How to restore health to your metabolism (56:03/ 51:56) Mentioned in this episode Perspective: Obesity—an unexplained epidemic Competing paradigms of obesity pathogenesis: energy balance versus carbohydrate-insulin models Daily energy expenditure through the human life course Get a copy of Dr. Li’s book, Eat to Beat Disease: The New Science of How Your Body Can Heal Itself, here and check out his Masterclass with Dr. William Li here.

This episode is brought to you by Rupa Health, Thrive Market, and Comvita. Today, as part of my Masterclass series, I’m answering personal questions my team put together from the “Let’s Get Closer” card deck. I am joined by my good friend and podcast host, Dhru Purohit, to give you a peek into my personal life as I answer questions about my greatest struggles, what I’m addicted to, the best advice I’ve received, and much more. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health, Thrive Market, and Comvita. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Thrive Market is an online membership-based grocery store that makes eating well convenient and more affordable. Join today at thrivemarket.com/hyman to receive an extra $80 worth of free groceries with your first order. Comvita offers the most premium, pure, well-researched, and sustainably sourced Manuka products available on the market today. You can learn more at comvita.com, and enter code Hyman25 for 25% off all Manuka honey and bee products. (This offer does not apply to bundles or sale items.) In this episode, we discuss (audio version / Apple Subscriber version): The last time I asked for help (5:20 / 2:12) A time when I felt the most alive (7:04 / 4:45) The way I like to be comforted when I’m sad or upset (12:00 / 9:38) What I am addicted to (14:08 / 11:47) What I miss about being a kid (21:42 / 18:03) Characteristics I most admire in others (25:06 / 21:26) The greatest struggles I’ve overcome (25:50 / 22:10) The best advice I’ve received (27:57 / 24:18) My biggest fear (30:34 / 26:54) My definition of success (33:14 / 29:37) The most miraculous thing I’ve experienced (34:55 / 31:17) Something I can’t explain (40:55 / 37:15) How I’d like to be remembered (46:28 / 42:50) Mentioned in this episode: Let’s Get Closer by Intelligent Change Inner.U How to Conquer Your Mind to Live Your Best Life with Colin O’Brady The Spontaneous Fulfillment of Desire by Deepak Chopra

This episode is brought to you by ButcherBox and Athletic Greens. Our gut is a powerful control center, due to its bidirectional communication with the brain, which we call the gut-brain axis. This links the emotional and cognitive centers of the brain with intestinal function. Certain conditions, such as irritable bowel syndrome (IBS), are tied to imbalances in the gut-brain axis and can benefit from taking a systems approach in healing, which includes looking at diet, the microbiome, stress management, and more. In today’s episode, I talk with Dr. Todd LePine, Dr. Emeran Mayer, and Dr. George Papanicolaou about various root causes of irritable bowel syndrome, including microbiome imbalance, parasites, and stress. Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine certified practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. Dr. Emeran Mayer is the author of The Gut-Immune Connection as well as The Mind-Gut Connection. He has studied brain-body interactions for the last 40 years, is the executive director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience, and is the founding director of the UCLA Brain Gut Microbiome Center at the University of California at Los Angeles. His research has been supported by the National Institutes of Health for the past 25 years, and he is considered a pioneer and world leader in the area of brain-gut microbiome interactions and its clinical implications.⁣ Dr. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is board certified in Family Medicine from Abington Memorial Hospital. He is also an Institute for Functional Medicine practitioner. He worked on the Navajo reservation for four years at the Chinle Comprehensive Medical Facility, where he served as the Outpatient Department Coordinator. In 2000, he founded Cornerstone Family Practice in Rowley, MA. In 2015, he established Cornerstone Personal Health, a practice dedicated entirely to Functional Medicine. Dr. Papanicolaou joined The UltraWellness Center in 2017. This episode is brought to you by ButcherBox and Athletic Greens. If you sign up today, ButcherBox will give you two ribeye steaks for free in your first box. Just go to butcherbox.com/farmacy to claim this deal. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Full-length episodes of these interviews can be found here: Dr. Todd LePine Dr. Emeran Mayer Dr. George Papanicolaou

This episode is brought to you by Mitopure, InsideTracker, and Rupa Health. The topic of veganism is hotly debated in terms of health and environmental stewardship. But how did the idea that being vegan is the best way to eat for our bodies and the planet develop in the first place? The answer is more complex than you might think. On this episode of The Doctor’s Farmacy, Jayne Buxton challenges the notion that veganism is the cure for disease and climate change and explains how we got here. A British-Canadian, Jayne Buxton is an author of both fiction and non-fiction. She spent fifteen years doing research-intensive work as a management consultant for a major firm before writing her 1998 book, Ending the Mother War: Starting the Workplace Revolution, which explored the entrenched positions and false choices faced by women wanting to combine motherhood with careers. Jayne subsequently spent years working in the field of work-life balance, advising both parents and corporations, before turning to writing full time. Her new book, The Great Plant-Based Con, challenges the dominant narrative about the vegan diet and proposes a compelling new perspective. This episode is brought to you by Mitopure, InsideTracker, and Rupa Health. Get 10% off Mitopure at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Here are more details from our interview (audio version / Apple Subscriber version): The origins of the overarching mythology that veganism is best for human, animal, and planetary health (5:04 / 2:24) How Big Food, Big Agriculture, and Big Pharma benefit from widespread veganism (7:17 / 4:50) Why the movie The Game Changers was a tipping point for Jayne to write her book (10:58 / 8:13) Countries that have banned vegan diets for children (14:55 / 12:07) My experience treating vegan patients (19:01 / 16:07) Frequent health issues that occur from vegan diets (22:50 / 18:08) Navigating the science, and subsequent dietary recommendations, around vegan diets and eating meat (29:54 / 25:27) Building soil health through regenerative agriculture (51:05 / 45:35) Pervasive myths around cows and methane production (55:05 / 50:40) Jayne’s recommendations for how to eat for optimal human, animal, and planetary health (1:03:53 / 59:38) Learn more about Jayne Buxton and her work at thegreatplantbasedcon.com and get her book, The Great Plant-Based Con: Why eating a plants-only diet won't improve your health or save the planet, here.

This episode is brought to you by Rupa Health, Levels, and Pendulum. Today, as part of my Masterclass series, I’m answering questions submitted by my community through the video app HiHo. I am joined by my good friend and podcast host, Dhru Purohit, to discuss back inflammation, intermittent fasting, treating type 2 diabetes with diet, and much more. Find a link below to follow me on HiHo and we may select your question for a future episode! Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health, Levels, and Pendulum. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. By leveraging biosensors like continuous glucose monitors (CGM), Levels provides real-time feedback on how diet and lifestyle choices impact your metabolic health. Learn more about Levels by going to levels.link/HYMAN. Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20. In this episode, we discuss (audio version / Apple Subscriber version): My recent back injury (4:46 / 1:07) Back inflammation and nerve impingement (10:58 / 7:37) Intermittent fasting (12:08 / 8:45) Treating type 2 diabetes with diet (26:17 / 21:25) Healing cystic acne from the inside out (32:43 / 27:55) Changing the food paradigm (37:57 / 32:49) Follow me on HiHo here! Mentioned in this episode: Calorie Restriction with or without Time-Restricted Eating in Weight Loss The Carbohydrate-Insulin Model of Obesity: Beyond ‘Calories In, Calories Out’ The Carbohydrate-Insulin Model: a Physiological Perspective on the Obesity Pandemic Perspective: Obesity—an unexplained epidemic Food Fix

This episode is brought to you by Rupa Health and Athletic Greens. Every day, 80 million Americans are dealing with some form of autoimmune disease, including Hashimoto’s. Hashimoto’s is the leading cause of hypothyroidism (i.e., an underactive thyroid) in the US, and roughly 14 million people are struggling with this diagnosis. The conventional approach to treating it is based almost entirely on suppressing symptoms with drugs. However, with a Functional Medicine approach, there are so many other steps for treating the thyroid. I talk with Dr. George Papanicolaou, Dr. Elizabeth Boham, and Dhru Purohit about why thorough testing is necessary for identifying Hashimoto’s and how lifestyle changes, such as removing gluten, could help to treat this condition. Dr. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is board certified in Family Medicine from Abington Memorial Hospital. He is also an Institute for Functional Medicine practitioner. Upon graduation from his residency he joined the Indian Health Service. He worked on the Navajo reservation for four years at the Chinle Comprehensive Medical Facility, where he served as the Outpatient Department Coordinator. Dr. Papanicolaou joined The UltraWellness Center in 2017. Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Full-length episodes of these interviews can be found here: Dr. George Papanicolaou Dr. Elizabeth Boham Dhru Purohit

This episode is brought to you by InsideTracker, BiOptimizers, and Comvita. Several months ago, I took thirty days to be by myself in a secluded Vermont cabin. I had no phone, no podcasts, no music, no TV, no work, and no company—it was just me and my thoughts. And I can’t tell you how refreshed, recharged, and centered I felt after that trip. It can be incredibly hard spending time alone with your inner self, but it’s always rewarding. That’s what today’s conversation with my good friend Colin O’Brady is all about. Colin is a ten-time world record breaking explorer, New York Times bestselling author, entrepreneur, speaker, and expert on mindset. He is focused on sharing his hard-won wisdom to encourage others to step outside of their comfort zone and unlock their best lives. Colin’s highly publicized expeditions have been seen by millions and his work has been featured by The New York Times, The Tonight Show, BBC, Forbes, and Today. His world-renowned feats include the world’s first solo, unsupported, and fully human-powered crossing of Antarctica, speed records for the Explorers Grand Slam and the Seven Summits, as well as the first human-powered row across Drake Passage. He is a regular speaker at Fortune 100 companies like Nike, Google, and Amazon and top Universities including UPenn, Georgetown, and Johns Hopkins. This episode is brought to you by InsideTracker, BiOptimizers, and Comvita. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Go to magbreakthrough.com/hyman and use code hyman10 at checkout for 10% off your next order of BiOptimizers Magnesium Breakthrough. Learn more about Comvita at comvita.com, and enter code Hyman25 for 25% off all Manuka honey and bee products. Note: Does not apply to bundles or sale items. Here are more details from our interview (audio version / Apple Subscriber version): Colin’s solo crossing of Antarctica (7:44 / 3:27) The personalized nutrition food bars Colin ate on his expedition (9:37 / 6:55) The advice Colin’s wife gave him on the first day of his Antarctica crossing (18:51 / 15:51) How Colin broke out of a period of anxiety and depression (27:24 / 23:53) Conquering your own mind (31:18 / 27:14) The experience that led me to become a doctor (41:34 / 37:18) Facing the feeling of not having enough time (43:50 / 39:31) What Colin fears more than dying (47:35 / 43:22) Becoming unstuck from the zone of comfortable complacency (49:10 / 46:54) The severe burn injury that served as a major turning point in Colin’s life (54:59 / 52:00) Learn more about Colin at colinobrady.com and get a copy of his new book, The 12-Hour Walk: Invest One Day, Conquer Your Mind, and Unlock Your Best Life, here. Get a copy of Colin’s book, The Impossible First: From Fire to Ice―Crossing Antarctica Alone, here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear Part II of a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on treating and preventing osteoporosis with Dr. Elizabeth Board. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, Paleovalley, and Vuori. Today, as part of my Masterclass series, I’m answering questions submitted by my community through the video app HiHo. I am joined by my good friend and podcast host, Dhru Purohit, to discuss a variety of topics including hair loss, supporting your liver, food and pet allergies, and so much more. Find the link below to follow me on HiHo and we may select your question for a future episode! Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health, Paleovalley, and Vuori. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. It’s the perfect time to upgrade your wardrobe! Vuori is offering my community 20% off your first purchase. Just head over to vuori.com/farmacy to claim this deal. In this episode, we discuss (audio version / Apple Subscriber version): Hair loss and your diet (4:07 / 00:57) The best way to support the liver (8:51 / 5:42) Heal alopecia areata by eliminating gluten (19:21 / 14:37) Staying healthy while working long shifts (21:16 / 16:32) The root cause of allergies (26:15 / 21:26) Choosing the right type of fasting for you (32:23 / 27:38) What’s the deal with cheese? (34:37 / 29:48) Healing dry skin from the inside out (39:00 / 34:17) Medication for high blood pressure (41:12 / 36:22) Follow me on HiHo here! Mentioned in this episode: This American Life: As the Worm Turns Betty Body with Dr. Stephanie Estima

This episode is brought to you by Rupa Health and Athletic Greens. Osteoporosis is very common, especially as we age, but it doesn’t have to be the life-threatening risk that currently it is. We’ve been led to believe that getting enough calcium is the key to healthy bones. In truth, your bone health is determined by your diet, gut health and nutrient absorption, physical activity levels, muscle mass, and more. I talk with Dr. Todd LePine, Dr. David Ludwig, and Dhru Purohit about the myths surrounding bone health and why it’s important to take steps to strengthen your bones at every age. Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine certified practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. David S. Ludwig, MD, PhD, is an endocrinologist and researcher at Boston Children’s Hospital. He holds the rank of Professor of Pediatrics at Harvard Medical School and Professor of Nutrition at Harvard School of Public Health. Dr. Ludwig is codirector of the New Balance Foundation Obesity Prevention Center and founder of the Optimal Weight for Life program, one of the country’s oldest and largest clinics for the care of overweight children. For more than 25 years, Dr. Ludwig has studied the effects of dietary composition on metabolism, body weight, and risk for chronic disease. Described as an “obesity warrior” by Time Magazine, Dr. Ludwig has fought for fundamental policy changes to improve the food environment. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Full-length episodes of these interviews can be found here: Dr. Todd LePine Dr. David Ludwig Dhru Purohit

This episode is brought to you by ButcherBox, InsideTracker, and Cozy Earth. The common medical approach to psychiatric disorders is to treat the symptoms. But the truth is that we just don’t know how the biological, psychological, and social risk factors and symptoms of these problems fit together. We don’t know what the underlying pathology is. I was excited to talk to Dr. Christopher Palmer who is disrupting the paradigm of psychiatry, about new ways of treating psychiatric disorders, specifically with the ketogenic diet and mitochondrial repair. Dr. Palmer is a psychiatrist and researcher working at the interface of metabolism and mental health. He is the Director of the Department of Postgraduate and Continuing Education at McLean Hospital and an Assistant Professor of Psychiatry at Harvard Medical School. For over 25 years, he has held leadership roles in psychiatric education, conducted research, and worked with people who have treatment-resistant mental illnesses. He has been pioneering the use of the medical ketogenic diet in the treatment of psychiatric disorders—conducting research, treating patients, writing, and speaking around the world on this topic. This episode is brought to you by ButcherBox, InsideTracker, and Cozy Earth. Sign up today and get two ribeye steaks for free in your first ButcherBox. Just go to butcherbox.com/farmacy. InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Here are more details from our interview (audio version / Apple Subscriber version): Why mental illness happens and is so hard to treat (6:33 / 3:51) The patient who changed the way Dr. Palmer treats mental illness (11:06 / 8:08) The ketogenic diet as a treatment for epilepsy, seizure disorders, and mental health disorders (17:03 / 14:09) Getting to the root cause of inflammation in the brain (20:16 / 17:26) Viewing mental disorders as metabolic disorders of the brain (27:37 / 23:20) Mitochondrial energy deficits in children with autism (34:28 / 30:03) Improve mitochondrial function (35:14 / 31:20) Addressing inflammation in the body (42:16 / 38:00) Validating a multifaceted approach to treating mental health disorders (47:55 / 44:39) Dr. Palmer’s experience treating a child with ADHD (57:23 / 52:52) Children with high levels of insulin resistance and associated risk for schizophrenia, bipolar disorder, and depression (59:05 / 54:42) Referenced in this episode: Before & after handwriting from Dr. Hyman’s patient Learn more about Dr. Palmer here. Get his book, Brain Energy: A Revolutionary Breakthrough in Understanding Mental Health—and Improving Treatment for Anxiety, Depression, OCD, PTSD, and More, here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health and InsideTracker. Today, as part of my Masterclass series, I’m answering questions submitted by my community through the video app HiHo. I am joined by my good friend and podcast host, Dhru Purohit to discuss the role of the gut microbiome in OCD, my approach to treating Lyme disease, the best ways to detox, and much more. Find a link below to follow me on HiHo and we may select your question for a future episode! Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. In this episode, we discuss (audio version / Apple Subscriber version): OCD and its connection to the gut (3:24 / 00:52) Treating persistent Lyme disease (12:02 / 9:38) Addressing ringing in the ear, or tinnitus (25:46 / 23:18) Ways to detox the body (27:55 / 25:28) The whole body approach to treating lupus (33:47 / 31:21) Follow me on HiHo here! Mentioned in this episode: Gut Food IFM Find a Functional Medicine Practitioner Find a Trained Ozone Therapy Practitioner

This episode is brought to you by Athletic Greens and Paleovalley. If there was something you could do every day to boost your focus and productivity, feel energized, reduce stress, sleep better, maintain a positive outlook, and support whole-body health, wouldn’t you do it? It’s for all these reasons, and more, that meditation is a foundational pillar to good health. In today’s episode, I talk with Daniel Goleman, Emily Fletcher, and Dr. Joe Dispenza about how meditation changes lives by reducing stress, creating resilience, and improving emotional intelligence. Daniel Goleman is best known for his worldwide bestseller Emotional Intelligence and most recently coauthored the book Altered Traits: Science Reveals How Meditation Changes Your Mind, Brain, and Body. Goleman has been ranked among the 25 most influential business leaders by several business publications including Time and the Wall Street Journal. Apart from his writing on emotional intelligence, Goleman has written books on topics including self-deception, creativity, transparency, meditation, social and emotional learning, eco-literacy, and the ecological crisis. Emily Fletcher is the founder of Ziva, the creator of The Ziva Technique, and a leading expert in meditation for high performers. She is also the author of Stress Less, Accomplish More. Dr. Joe Dispenza’s passion can be found at the intersection of the latest findings from the fields of neuroscience, epigenetics, and quantum physics to explore the science behind spontaneous remissions. He uses that knowledge to teach people how to heal their bodies of health conditions, make significant changes in their lives, and evolve their consciousness. Since 2010, he has partnered with scientists and universities to perform extensive research on the effects that meditation has on the brain and body. He and his team have also studied gene expression, protein regulation, immune response, neurotransmitter changes, telomere length, and variations in bioactive cellular metabolic particles in novice and advanced meditators. This episode is brought to you by Athletic Greens and Paleovalley. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Full-length episodes of these interviews can be found here: Daniel Goleman Emily Fletcher Dr. Joe Dispenza

This episode is brought to you by BiOptimizers, Rupa Health, and Pendulum. What’s the point in living a long time? Being fully in contribution to life. I want to do that feeling healthy and vital, not sick and decrepit. Everything we do speaks to our genes—the food we eat, our relationships, our environment. You’re either telling your genes to age faster or age slower. So I’m constantly working on how to give my genes the right information to do the latter. Today’s podcast episode was recorded on my recent trip to Antarctica with my own doctor, Dr. Matt Cook. He’s helped me heal and has integrated so many different forms of technologies and science to rebuild people’s health from the ground up. Dr. Cook is the Founder of BioReset® Medical. He is a board-certified anesthesiologist with over 20 years of experience practicing medicine, focusing the last 14 years on Functional and Regenerative Medicine. He graduated from the University of Washington School of Medicine, completed his anesthesiology residency at the University of California San Francisco (UCSF), and completed a fellowship in Functional Medicine. This episode is brought to you by BiOptimizers, Rupa Health, and Pendulum. BiOptimizers Magnesium Breakthrough formula contains seven different forms of magnesium, all of which have different functions in the body. There is truly nothing like it on the market. Go to magbreakthrough.com/hyman and use code hyman10 at checkout for 10% off your next order. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20. Here are more details from our interview (audio version / Apple Subscriber version): What’s the point of living a long life? (5:38 / 2:23) What I learned from my travel through the Blue Zones (6:36 / 3:25) Five converging trends that will change our thinking about medicine and health (13:33 / 10:16) The root causes of aging (18:16 / 15:02) Influence your genes to reverse your biological age (22:29 / 17:42) How to eat to extend your life span (28:40 / 24:01) Practices and supplements to support healthy aging (35:51 / 31:23) Regenerative medicine therapies and protocols (48:12 / 42:13) What the Yamanaka factors teach us about aging (1:13:12 / 1:08:31) Reimaging how we deal with trauma (1:21:21 / 1:16:49) Learn more about Dr. Matt Cook and his work at BioReset Medical at bioresetmedical.com.

This episode is brought to you by Rupa Health, Thrive Market, and InsideTracker. Today, as part of my Masterclass series, I’m answering questions submitted by my community through the video app HiHo. I am joined by my good friend and podcast host, Dhru Purohit, to discuss how to reduce your biological age, what to do if you have a low sex drive, the Functional Medicine approach to treating osteoporosis, and much more. Find a link below to follow me on HiHo and we may select your question for a future episode! Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health, Thrive Market, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Thrive Market is an online membership-based grocery store that makes eating well convenient and more affordable. Join today at thrivemarket.com/hyman to receive an extra $80 of free groceries with your first order. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. In this episode, we discuss (audio version / Apple Subscriber version): What do high homocysteine levels mean? (3:44 / 00:52) Tips to reduce our biological age (17:23 / 13:42) The connection between grip strength, muscle loss, and aging (23:15 / 18:46) Causes of low sex drive and how to correct them (28:19 / 23:42) The root cause and treatment for PCOS (32:44 / 28:04) The Functional Medicine approach to osteoporosis and increasing bone density (37:47 / 33:42) Follow me on HiHo here! Mentioned in this episode: True Diagnostics Nordic Labs Why Muscle Is the Key to Longevity with Dr. Gabrielle Lyon Are We Eating Too Much (Or Not Enough) Protein for Good Health with Dr. Gabrielle Lyon

This episode is brought to you by Athletic Greens and InsideTracker. This myth is pervasive throughout medicine: if you know the name of your disease, you know what’s wrong with you. In truth, diagnoses are just names we associate with a collection of symptoms. They tell us nothing about why someone has those symptoms—the root causes of the “disease.” Functional Medicine seeks to dig deeper to look for the root cause of symptoms. In today’s episode, I talk with Dr. Elizabeth Boham, Dr. Todd LePine, and Dr. George Papanicolaou about how patients miss out on true healing when the root cause of their symptoms is not addressed. Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing, she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing. Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. Dr. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is board certified in Family Medicine from Abington Memorial Hospital. He is also an Institute for Functional Medicine Practitioner. In 2000, he founded Cornerstone Family Practice in Rowley, MA. He practiced with a philosophy centered on personal relationships and treating the whole person, not just not the disease. He calls his philosophy “Whole Life Wellness.” Over time, as the healthcare system made it harder for patients to receive this kind of personal care, Dr. Papanicolaou decided a change was needed. He began training in Functional Medicine through the Institute of Functional Medicine. In 2015, he established Cornerstone Personal Health, a practice dedicated entirely to Functional Medicine. Dr. Papanicolaou joined The UltraWellness Center in 2017. This episode is brought to you by Athletic Greens and InsideTracker. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Full-length episodes of these interviews can be found here: Dr. Elizabeth Boham Dr. Todd LePine Dr. George Papanicolaou

This episode is brought to you by Cozy Earth, Rupa Health, and Mitopure. Near-death experiences aren’t that uncommon for the world’s most technical mountaineers. Summiting Mt. Everest is sure to leave anyone feeling truly awe-inspired. Completing the climb and getting home safely after nearly dying creates a whole different level of reflection. Today on The Doctor’s Farmacy, I talk to Hakan Bulgurlu about turning his near-death experience into a force for positive change in his personal life, the climate crisis, business leadership, and more. Hakan is a global business leader and a climate activist. As the CEO of Arçelik, a home appliances manufacturer that operates in 150 countries, he is a thought leader on sustainable and purpose-driven business. In a bid to raise awareness of the climate crisis, Hakan climbed Everest in 2019. He wrote A Mountain to Climb; a retelling of his journey to Everest, accompanied by his research into the possible solutions to the climate crisis. This episode is brought to you by Cozy Earth, Rupa Health, and Mitopure. ​​Cozy Earth makes the most comfortable, temperature-regulating, and nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Mitopure is the first and only clinically tested pure form of a natural gut metabolite called urolithin A that clears damaged mitochondria away from our cells and supports the growth of new, healthy mitochondria. Get 10% off at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Here are more details from our interview (audio version / Apple Subscriber version): How Hakan’s preparation for climbing Mt. Everest led to business solutions to the climate crisis (6:26 / 3:45) Hakan’s “aha” moment that shifted his approach to business (11:25 / 8:42) A profitable business solution to the issue of microplastics in the oceans (13:50 / 11:43) The two types of CEOs (20:09 / 17:35) Improving the energy efficiency of refrigerators (20:50 / 18:10) Hakan’s early influential life experiences (26:27 / 22:07) Hakan’s Mt. Everest climb, his near-death experiences, and how they affected him (29:20 / 24:55) Building the price of climate issues into the market cost (41:22 / 35:14) Humans’ relationship to nature (48:49 / 44:08) Responding to our depression about the state of the climate (50:55 / / 46:20) Get your copy of Hakan’s book, A Mountain to Climb: The Climate Crisis: A Summit Beyond Everest, here.

This episode is brought to you by Rupa Health, Levels, and HigherDOSE. I’m willing to bet all of us would feel a whole lot better about aging if it didn’t actually mean feeling old. Well, I’m here to tell you it doesn’t have to; aging can mean another year of joy, adventure, and spending time with people we love—all while feeling great. Today, as part of my Masterclass series, I am joined by my good friend and podcast host, Dhru Purohit, to answer a question submitted by my community through the video app HiHo about the benefits of hot and cold therapy. We also discuss why adequate protein is vital as we age and how to turn on longevity switches in our bodies to live a longer, healthier life. Find a link below to follow me on HiHo and we may select your question for a future episode! Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health, Levels, and HigherDOSE. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. By leveraging biosensors like continuous glucose monitors (CGM), Levels provides real-time feedback on how diet and lifestyle choices impact your metabolic health. Learn more about Levels by going to levels.link/HYMAN. Right now, you can get your own Infrared Sauna Blanket or Infrared PEMF Mat at HigherDOSE.com. Use code FARMACY15 at check out to save 15% off OR just go to higherdose.com/hyman to get your 15% off today. In this episode, we discuss (audio version / Apple Subscriber version): The best way to do hot and cold therapy (4:13 / 00:48) My tips for hot and cold therapy while traveling (18:44 / 15:10) Integrating hot and cold therapy with exercise (19:48 / 16:18) The importance of adequate protein for strength training and healthy muscles as we age (30:14 / 25:00) Activating the mTOR longevity switch in the body (37:30 / 32:34) Using metformin or other drugs to hack longevity (48:37 / 43:20) Follow me on HiHo here!

This episode is brought to you by Gut Food, Athletic Greens, and Rupa Health. We are living in a time unlike any before. For multiple reasons, we are now unable to get optimal amounts of all of the nutrients we need to function the way we were designed to. That’s why we need to turn to certain supplements to combat the nutritional deficiencies—like vitamin D, magnesium, omega 3 fatty acids, and more—the majority of us are faced with. In today’s episode, I talk with Dhru Purohit, Dr. Elizabeth Boham, and Dr. James DiNicolantonio about why our modern diet and lifestyle are leaving us nutritionally deficient, the benefits of supplementation, and the importance of adequate magnesium levels. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing. Dr. DiNicolantonio is a Doctor of Pharmacy and a cardiovascular research scientist. A well-respected and internationally known scientist and an expert on health and nutrition, he has contributed extensively to health policy and has testified in front of the Canadian Senate regarding the harms of added sugars. He serves as the associate editor of the British Medical Journal’s Open Heart, a journal published in partnership with the British Cardiovascular Society, and is on the editorial advisory boards of several other medical journals. Dr. DiNicolantonio is the author or coauthor of over 250 publications in the medical literature. He is also the author of five bestselling health books: The Salt Fix, Superfuel, The Longevity Solution, The Immunity Fix, and The Mineral Fix. This episode is brought to you by Gut Food, Athletic Greens, and Rupa Health. Check out Gut Food at gutfood.com. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Full-length episodes of these interviews can be found here: Dhru Purohit Dr. Elizabeth Boham Dr. James DiNicolantonio

This episode is brought to you by Gut Food, BiOptimizers, InsideTracker, and Pendulum. Relationships can feel complicated. We often go into them looking for others to fulfill whatever we refuse to give ourselves. We want our unmet needs to be met by this other person, without doing the inner work to help ourselves. Owning our needs actually makes it easier for other people to meet our needs. This sounds counterintuitive, but it’s one of those breakthroughs that can really turn toxic relationship patterns around. Today I’m excited to share a conversation with my good friend Angelika Alana, all about tuning into our bodies, our physical and emotional needs, and healing our connection to ourselves and others. Angelika is the founder and CEO of the Somatic Healing Institute. She has been featured in Vanity Fair, Well+Good, and Modern Luxury. She certifies coaches and facilitators in her transformational body-based healing method. She has traveled and studied extensively in Indonesia, Brazil, Australia, and the UK, and is a massive foodie with her husband Patrick Drake, co-founder of Hello Fresh. This episode is brought to you by Gut Food, BiOptimizers, InsideTracker, and Pendulum. Check out Gut Food at gutfood.com. Go to magbreakthrough.com/hyman and use code hyman10 at checkout for 10% off your next order of BiOptimizers Magnesium Breakthrough. Right now, InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20. Here are more details from our interview (audio version / Apple Subscriber version): Angelika’s journey into somatic and sexual healing work (6:38 / 2:47) Getting out of your head and into your body (10:59 / 7:20) Creating space from our emotions to safely integrate pain (16:43 / 12:06) How to locate your wounds (21:15 / 17:10) Client stories from Angelika’s work (24:41 / 19:28) What happens in a typical somatic healing session? (34:12 / 28:59) Moving out of a toxic relationship framework (38:24 / 33:12) How to know if you’re in a toxic relationship or a healing relationship (42:29 / 37:12) Learning new skills to succeed in sex and relationships (49:32 / 42:32) Holding more complexity with care (54:02 / 49:03) Learn more about Angelika’s work at angelikaalana.com. Access her Somatic Self Care, Level 1 Training here, information about her upcoming retreat here, and a free guided somatic mindfulness practice here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on treating and preventing osteoporosis with Dr. Elizabeth Board. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Gut Food, Rupa Health, ButcherBox, and InsideTracker. Our gut, and the tons of bacteria that reside within it, regulates many of our bodily functions, from creating vitamins to controlling our immune system, our brain function, and, of course, our metabolism and weight. The gut is the number-one place to investigate when healing the body of any chronic symptoms or diseases. If your gut isn’t healthy, you’re not healthy! In this episode of my Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about why prebiotics are vital in creating a healthy gut. These are the things your good gut bugs love to munch on. In turn, they produce beneficial compounds such as short-chain fatty acids, which have been shown to help prevent things like colon cancer. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Gut Food, Rupa Health, ButcherBox, and InsideTracker. Check out Gut Food at gutfood.com. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. Sign up today for ButcherBox and get two ribeye steaks free in your first box by going to butcherbox.com/farmacy. Right now, InsideTracker is offering my community 20% off at insidetracker.com/drhyman. In this episode, we discuss (audio version / Apple Subscriber version): Why is gut health so crucial? (6:07 / 1:46) Resistant starch (9:48 / 5:33) How and why to increase short-chain fatty acids (13:56 / 9:42) The many benefits of acacia fiber (16:19 / 11:58) Galactooligosaccharides for gut health (18:22 / 14:00) Probiotics, prebiotics, and polyphenols in my meals (21:44 / 16:00) One prebiotic food that everyone should consider eating (24:39 / 19:00) Questions from my community (27:27 / 21:42) Podcasts, Products, & Research Mentioned Disclaimer: This podcast is for educational purposes only. This podcast is not a substitute for professional care by a doctor or other qualified medical professional. You should always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal, or homeopathic supplement, or adopting any treatment for a health problem. The use of Gut Food or any other products or services purchased by you as a result of this podcast does not create a doctor-patient relationship between you and any of the physicians affiliated with this podcast. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

This episode is brought to you by Gut Food, Vuori, and Paleovalley. Have you ever wondered what the worst candy or cereal for your blood sugar is, or what the best thing to order at your favorite restaurant might be? Thanks to continuous glucose monitors, this is knowledge we’ll all be able to take advantage of in the near future. With insulin resistance playing a key role in the majority of the chronic diseases of our time, monitoring how our blood sugar responds to different foods is a huge step towards health. In today's episode, I talk with Dr. Casey Means, Jessie Inchauspé, and Dhru Purohit about the best and the worst foods to eat for glucose management, as well as tips and tricks for combining food for optimal blood sugar balance. Dr. Casey Means is a Stanford-trained physician, Chief Medical Officer and Cofounder of the metabolic health company Levels, an associate editor of the International Journal of Disease Reversal and Prevention, and a guest lecturer at Stanford University. Her mission is to maximize human potential and reverse the epidemic of preventable chronic disease by empowering individuals with tools that can facilitate a deep understanding of our bodies and inform personalized and sustainable dietary and lifestyle choices. Jessie holds a bachelor’s degree in mathematics from King's College London and a master’s degree in biochemistry from Georgetown University. Her work at a genetic analysis start-up in Silicon Valley made her realize that, as the key to good health, food habits beat genetics. In her first book, Glucose Revolution, Jessie shares her startling discovery about the essential role of blood sugar in every aspect of our lives, from cravings to fertility, and the surprising hacks to optimize it while still eating the foods we love. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Gut Food, Vuori, and Paleovalley. Check out Gut Food at gutfood.com. Vuori is offering my community 20% off your first purchase. Just head over to vuori.com/farmacy to claim this deal. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Full-length episodes of these interviews can be found here: Dr. Casey Means Jessie Inchauspé Dhru Purohit

This episode is brought to you by Gut Food, Cozy Earth, InsideTracker, and Rupa Health. Many of us are feeling a crisis of meaning; feeling we’ve lost our way amongst the stressors and distractions of modern life. We are more isolated, divided, and sick than ever before. Personally, I always turn to nature when I’m feeling lost. And in traveling, talking to interesting people, and learning about the world, I’ve found that ancient cultures and their relationships to nature can teach us volumes when it comes to rediscovering connection, health, and meaning. Today, I’m excited to share a conversation I had with Wade Davis, all about culture, the depth of the natural world, belief systems, ethnobotany, psychedelics, and more. Wade Davis is a writer, photographer, and filmmaker. Explorer-in-Residence at the National Geographic Society from 2000 to 2013, he is currently Professor of Anthropology and the BC Leadership Chair in Cultures and Ecosystems at Risk at the University of British Columbia. He is the author of 23 books, including One River, The Wayfinders, and Into the Silence, and he was the winner of the 2012 Samuel Johnson prize, the top nonfiction prize in the English language. His latest book is Magdalena: River of Dreams. Wade’s many film credits include Light at the Edge of the World, an eight-hour documentary series written and produced for the NGS. This episode is brought to you by Gut Food, Cozy Earth, InsideTracker, and Rupa Health. Check out Gut Food at gutfood.com. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Right now, InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Here are more details from our interview (audio version / Apple Subscriber version): Wade’s early experiences that first got him interested in anthropology (5:56 / 3:24) Why western culture is actually an anomaly, not the norm (7:57 / 5:23) Our misguided understanding of the purpose of culture (18:00 / 15:50) Why ancient wisdom matters in the modern world (20:40 / 18:57) The nature of life (22:48 / 20:50) Human commonalities among all cultural expressions (27:30 / 23:08) The value of language and storytelling (29:36 / 24:28) Why biologically, the concept of race is utter fiction (31:27 / 27:06) Psychedelics and our relationship to nature and plant medicines (37:27 / 33:20) Communicating with plants (1:01:22 / 39:35) Learn more about Wade Davis at daviswade.com.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Gut Food, Rupa Health, Athletic Greens, and InsideTracker. Probiotics are critical to protecting and rebuilding the gut. They compete with bad gut bugs and yeast, modulate intestinal function, and are essential to changing and improving immune function. They are also anti-inflammatory, they help us break down food, and they build nutrients. In this episode of my Masterclass series, the second in a series on gut health, I am interviewed by my good friend and podcast host, Dhru Purohit, about how probiotics work in the gut, the best fermented foods to eat, and much more. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Gut Food, Rupa Health, Athletic Greens, and InsideTracker. Check out Gut Food at gutfood.com. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. When you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. InsideTracker is offering my community 20% off at insidetracker.com/drhyman. In this episode, we discuss (audio version / Apple Subscriber version): Why we need probiotics (5:32 / 1:52) Top insults to our gut (7:04 / 3:25) Evaluating store-bought probiotics, including kombucha (8:08 / 4:26) What probiotics do (10:06 / 6:28) Different strains for different symptoms (14:43 / 10:50) The top fermented foods (18:34 / 14:46) Bacteria in the gut and your immune system (24:05 / 18:51) Who shouldn’t eat fermented foods (26:25 / 20:18) Steps to shape up our guts (28:48 / 23:46) The downside of antibiotics and supporting the gut (34:15 / 28:57) Products and Research Studies Mentioned in This Episode Disclaimer: This podcast is for educational purposes only. This podcast is not a substitute for professional care by a doctor or other qualified medical professional. You should always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal, or homeopathic supplement, or adopting any treatment for a health problem. The use of Gut Food or any other products or services purchased by you as a result of this podcast does not create a doctor-patient relationship between you and any of the physicians affiliated with this podcast. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

This episode is brought to you by Gut Food, ButcherBox, and Paleovalley. Heart disease is the number-one killer in the world, and it is often thought of as a cholesterol problem. When you take a closer look, however, there are other factors that drive this chronic disease that can’t be fixed by the most commonly prescribed medication: statin drugs. The way you eat, how much you exercise, how you manage stress, and more all contribute to heart disease. In this episode, I talk with Dr. Aseem Malhotra, Dr. Stanley Hazen, and Dr. Cindy Geyer about why heart disease is easier to prevent than to reverse, why statins are not the answer in most cases, and how the gut microbiome is connected to heart health. Dr. Aseem Malhotra is an NHS-trained consultant, cardiologist, and visiting professor of Evidence-Based Medicine at the Bahiana School of Medicine and Public Health in Salvador, Brazil. He is a pioneer of the lifestyle medicine movement in the UK and in 2018 was ranked by software company Onalytica as the number-one doctor in the world influencing obesity thinking. He is the author of, The Pioppi Diet, coauthored with Donal O'Neill, The 21-Day Immunity Plan, and, A Statin-Free Life. Dr. Stanley Hazen is both the chair of the Department of Cellular & Molecular Medicine at the Lerner Research Institute and section head of Preventive Cardiology & Rehabilitation at the Heart and Vascular Institute of the Cleveland Clinic. He’s published more than 400 peer-reviewed articles and has over 50 patents from his pioneering discoveries in atherosclerosis and inflammatory disease. Dr. Hazen made the seminal discovery linking microbial pathways to the pathogenesis of cardiovascular disease. Dr. Cindy Geyer received her Bachelor of Science and her Doctor of Medicine degrees, with honors, from the Ohio State University. She completed her residency in internal medicine at Strong Memorial Hospital in Rochester, NY, and is triple board certified in internal medicine, integrative medicine, and lifestyle medicine. She joined The Ultrawellness Center in 2021 after practicing and serving as the medical director at Canyon Ranch for 23 years. This episode is brought to you by Gut Food, ButcherBox, and Paleovalley. Gut Food uses the power of three critical gut-supporting components—prebiotics, probiotics, and polyphenols—and five ingredients at clinically validated dosages to help reduce inflammation, support the growth of beneficial gut bacteria, improve digestion and bloating, and support mood & energy. Check it out at gutfood.com. If you sign up today, ButcherBox will give you two ribeye steaks for free in your first box—just go to butcherbox.com/farmacy. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman. Full-length episodes of these interviews can be found here: Dr. Aseem Malhotra Dr. Stanley Hazen Dr. Cindy Geyer

This episode is brought to you by Gut Food, Rupa Health, BiOptimizers, and Beekeeper’s Natural. As humans, we’re natural storytellers. We like telling our friends the funny thing that happened at work, but we’re also really good at making up stories about things that happen in life and applying them to our identity and worldview. We can start believing these stories all too easily. But, they’re actually just stories! And we have a choice about what we believe and how we create our reality. I’m so excited to share this conversation I recently had with my good friend Dr. Rangan Chatterjee, all about cultivating greater health and happiness by breaking down the barriers we’ve put up in our own minds. Dr. Rangan Chatterjee is regarded as one of the most influential doctors in the UK. Host of the #1 Apple podcast, Feel Better, Live More, and presenter of BBC 1’s Doctor in the House, Dr. Chatterjee is the author of 5 Sunday Times bestselling books and his TED Talk, “How to Make Diseases Disappear,” has now been viewed over 4.8 million times. His newest book is Happy Mind, Happy Life: The New Science of Mental Well-Being. This episode is brought to you by Gut Food, Rupa Health, BiOptimizers, and Beekeeper’s Natural. ​​Gut Food uses the power of three critical gut-supporting components—prebiotics, probiotics, and polyphenols—and five ingredients at clinically validated dosages to help reduce inflammation, support the growth of beneficial gut bacteria, improve digestion and bloating, and support mood & energy. Check it out at gutfood.com. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. Go to magbreakthrough.com/hyman and use code hyman10 at checkout for 10% off your next order of BiOptimizers Magnesium Breakthrough. Beekeeper’s Natural have created a B.Fueled Bee Pollen and B.Powered Superfood honey that I’ve been loving. Head over to beekeepersnaturals.com/HYMAN and use code HYMAN for 25% off. Here are more details from our interview (audio version / Apple Subscriber version): The three pillars of core happiness (7:35 / 3:13) What we can learn from Holocaust survivors about happiness (10:58 / 7:06) Using moments of social friction to your own benefit (14:42 / 11:00) How happiness affects our health (20:28 / 16:22) The connection between illness and forgiveness (29:28 / 23:50) How your brain reacts when you’re triggered (34:29 / 29:14) Training your brain for happiness (36:12 / 30:16) Dr. Chatterjee’s morning routine (42:58 / 37:19) How your inner voice is affecting your happiness and health (46:20 / 41:32) Toxic positivity and happiness in the midst of grief and loss (1:02:59 / 57:22) Get a copy of Dr. Chatterjee’s new book, Happy Mind, Happy Life: The New Science of Mental Well-Being, here.

The gut microbiome plays a role in every disease, so why aren’t we doing more to protect and restore it? One third to one half of all Americans have gut issues due to the constant consumption of industrialized foods, glyphosate, food additives, and more. This is a problem—and it’s time for us to take action. In this episode of my Masterclass series, the first in a series on gut health, I am interviewed by my good friend and podcast host, Dhru Purohit, about the importance of polyphenols for our gut health. We also discuss my gut-health journey, which led me to dig deep into understanding the value of a healthy gut and diverse microbiome, and how to get there. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health, Thrive Market, and InsideTracker. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Join Thrive Market today at thrivemarket.com/hyman to receive an extra $80 of free groceries off with your first order. Right now, InsideTracker is offering my community 20% off at insidetracker.com/drhyman. In this episode, we discuss (audio version / Apple Subscriber version): The number-one thing that causes gut issues (3:57 / 1:28) Why are we in this mess? (5:08 / 2:37) My gut-health journey (12:29 / 9:43) What the research shows us about polyphenols (18:50 / 15:45) Compounds and phytochemicals in food that act like medicine (28:14 / 23:44) Two things that change a microbiome for the better (35:06 / 30:31) The best foods to incorporate into our diets (39:57 / 35:18) Zonulin and how it contributes to a leaky gut (51:11 / 45:55) Prebiotics, probiotics, and polyphenols found in Gut Food (1:02:38 / 57:58) The importance of powerful polyphenols (1:12:25 / 1:06:42) Mentioned in this episode: Therapeutic Potential of Rosmarinic Acid: A Comprehensive Review Gut Food Disclaimer: This podcast is for educational purposes only. This podcast is not a substitute for professional care by a doctor, or other qualified medical professional. You should always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or homeopathic supplement, or adopting any treatment for a health problem. The use of Gut Food or any other products or services purchased by you as a result of this podcast does not create a doctor-patient relationship between you and any of the physicians affiliated with this podcast. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

This episode is brought to you by Mitopure and Levels. Skin problems like acne, psoriasis, and eczema are often treated with over-the-counter lotions, creams, and potions or even with antibiotics. But while these options may reduce symptoms temporarily, they don't get to the root cause of the problem. In Functional Medicine, we dig deep to determine the underlying cause of skin issues, which often originate in the gut—treat the gut, and the skin clears up. In today’s episode, I talk with Dr. Elizabeth Boham, Dhru Purohit, and Dr. Todd LePine about the pathophysiology of acne, why diet matters for skin health, and how gut health is related to skin health. Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing, she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. Dr. LePine enjoys skiing, kayaking, hiking, camping, and golfing in the beautiful Berkshires and is a fitness enthusiast. This episode is brought to you by Mitopure and Levels. Mitopure is the first and only clinically tested, pure form of a natural gut metabolite called urolithin A that clears damaged mitochondria away from our cells and supports the growth of new, healthy mitochondria. Get 10% off at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. By leveraging biosensors like continuous glucose monitors (CGM), Levels provides real-time feedback on how diet and lifestyle choices impact your metabolic health. Learn more about Levels by going to levels.link/HYMAN. Full-length episodes of these interviews can be found here: Dr. Elizabeth Boham Masterclass with Dhru Purohit Dr. Todd LePine

This episode is brought to you by InsideTracker, HigherDOSE, and Rupa Health. Over the past few weeks, I’ve been sharing episodes from my Longevity Roadmap docu-series. We’ve covered how to optimize hormones, eat intentionally, increase and preserve brain function, and create healthy habits—all to help you live as well as possible for as long as possible. Today, we’re going to help you bring it all together. Most diseases of aging are starting younger and younger. So whether you’re in your 20s, 40s, 60s, or beyond, it’s never too late to prevent and even reverse the process we’ve come to call aging. Along with my colleagues Dr. Elizabeth Boham and Dr. Todd LePine, we’ll review the key takeaways you can start using right away to optimize your health for your specific phase of life. To get all of my longevity tips, sign up for my weekly Longevity newsletter at drhyman.com/longevity. This episode is brought to you by InsideTracker, HigherDOSE, and Rupa Health. ​​InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Get your own Infrared Sauna Blanket at HigherDOSE.com today and use my exclusive promo code FARMACY15 at check out to save 15% off, or just go to higherdose.com/hyman to get your 15% off today. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Here are more details from our interview (audio version / Apple Subscriber version): How to optimize health at every age and stage of life (5:20 / 1:44) Supporting your gut health as you age (7:43 / 4:08) The gut microbiome and its impact on cancer risk (12:03 / 8:30) Diagnostic testing to determine where you are on the aging spectrum (16:13 / 12:40) Making your body an unwelcome place for cancer growth (26:40 / 22:40) Assessing thyroid and overall hormone health (29:12 / 24:19) Assessing memory, cognitive function, and overall brain health (33:27 / 28:34) The importance of identifying your “why” for achieving optimal health and longevity (40:23 / 35:33)

This episode is brought to you by Rupa Health, Athletic Greens, and InsideTracker. ​​What you eat literally controls almost every function of your body and mind. Food connects us to one another and to our bodies. At the same time, what we eat is only one “ingredient” needed to make a healthy human. We need real, whole, fresh food, but we also need things like movement, connection, meaning, and purpose. When you take out the bad stuff and put in the good stuff, you create balance. Your body knows how to create health from those ingredients. In this episode, I feature an in-depth discussion on the importance of community, mindset, and optimism when it comes to increasing our healthspan from my Longevity Roadmap docu-series. In this series, I am joined by my colleagues at The UltraWellness Center: Elizabeth Boham, MD, MS, RD, Medical Director and Physician; Todd LePine, MD, Physician; and George Papanicolaou, DO, Physician. In this conversation we also delve into the fascinating topic of innovative anti-aging therapies based on the newest longevity research. To get all of my longevity tips, sign up for my weekly Longevity newsletter at drhyman.com/longevity. This episode is brought to you by Rupa Health, Athletic Greens, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): The commonalities between communities with the longest-lived, healthy people (4:13 / 1:06) The importance of your mindset as it relates to your health and gene expression (11:12 / 8:02) Mobility and health (14:39 / 11:28) Exercising for longevity (17:29 / 12:50) Understanding our body’s natural rhythms (18:21 / 15:16) Optimizing sleep (22:13 / 16:57) Emerging therapies for health and longevity (27:04 / 22:16) Keeping our mitochondria young (36:53 / 31:37) How small stressors to our body can be good for us (40:01 / 34:54) The foundational pillars of health (43:49 / 38:33)

This episode is brought to you by Athletic Greens and ButcherBox. Experiencing feelings of grief is a natural part of the human experience. While it can be difficult to sit with hard feelings such as grief, avoiding our emotions only makes them louder. Through practice, we can learn to accept our feelings in the moment. We can work to break the pattern of being at war with the present moment and let our feelings come and go as needed. In today’s episode, I talk with Dr. Joan Rosenberg, Susan David, and Tara Brach about situations that prompt grief, why facing our emotions is healthier than bottling them up, and how to accept difficult emotions. Dr. Joan Rosenberg is a cutting-edge psychologist who is known as an innovative thinker, acclaimed speaker, and trainer. A California-licensed psychologist, Dr. Rosenberg speaks on how to build confidence, emotional strength, and resilience; achieving emotional, conversational, and relationship mastery; integrating neuroscience and psychotherapy; and suicide prevention. She is the author of 90 Seconds to a Life You Love: How to Master Your Difficult Feelings to Cultivate Lasting Confidence, Resilience, and Authenticity. Susan David, PhD, is one of the world’s leading management thinkers and an award-winning Harvard Medical School psychologist. Her book, Emotional Agility, describes the psychological skills critical to thriving in times of complexity and change. Susan’s TED Talk on the topic went viral, with over 1 million views in its first week of release. She is a frequent contributor to Harvard Business Review, The New York Times, The Washington Post, and The Wall Street Journal and a frequent guest on national radio and television. Susan is the CEO of Evidence Based Psychology, on the faculty at Harvard Medical School, a cofounder of the Institute of Coaching (a Harvard Medical School/McLean affiliate), and on the Scientific Advisory Boards of Thrive Global and Virgin Pulse. Tara Brach holds a PhD in clinical psychology and teaches meditation internationally. Founder of the Insight Meditation Community of Washington, DC (IMCW), Tara is the author of the bestsellers Radical Acceptance, Radical Compassion, True Refuge, and her latest book, Trusting the Gold. Tara’s weekly podcasts are downloaded over 2 million times each month. This episode is brought to you by Athletic Greens and ButcherBox. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. When you sign up today, ButcherBox will send you 2 lbs of sustainably caught, wild Alaskan salmon in your first box for free. To receive this offer, go to ButcherBox.com/farmacy. Full-length episodes of these interviews can be found here: Dr. Joan Rosenberg Susan David Tara Brach