The Dr. Hyman Show

This episode is brought to you by Rupa Health, Paleovalley, and Essentia. The leading cause of inflammation is a poor diet—specifically one rich in addictive starches and refined sugars that keep us eating more than we need to because they don’t fill us up. This standard American diet (SAD) of refined flour and sugar is the gateway to insulin resistance, diabetes, and other metabolic issues, which cause rapid aging and chronic disease. In today’s episode, I talk with Dhru Purohit, Gary Taubes, and Dr. Ronesh Sinha about why we need to ditch the high-starch diet if we want to improve our metabolism and reduce chronic disease. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. ⁣Gary Taubes is an award-winning science and health journalist and cofounder and director of the Nutrition Science Initiative. He is the author of The Case Against Sugar, Why We Get Fat, Good Calories, Bad Calories, and The Case for Keto. Gary is a former staff writer for Discover and a correspondent for Science. He has written three cover articles on nutrition and health for The New York Times Magazine. Dr. Ronesh Sinha, author of The South Asian Health Solution, is an internal medicine physician who runs a lifestyle clinic in Silicon Valley focused on reversing insulin resistance in ethnically diverse patients. He is also an expert in corporate wellness and serves as the Chief Medical Officer for Silicon Valley Employer Forum, where he serves as a global adviser to shape health benefits for over 55 major Silicon Valley companies. This episode is brought to you by Rupa Health, Paleovalley, and Essentia. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Right now you can get an extra $100 off your mattress purchase, on top of Essentia’s holiday sale, which will also take 25% OFF your mattress purchase. Go to myessentia.com/drmarkhyman to learn more. Full-length episodes of these interviews can be found here: Dhru Purohit Gary Taubes Dr. Ronesh Sinha

This episode is brought to you by Rupa Health and Athletic Greens. CoQ10 is a compound whose job is to help cells generate energy, so it’s no surprise there are so many wonderful benefits to getting enough of this critical coenzyme. Although you can find it in supplement form, it is also naturally produced by the body. Unfortunately, however, as you age the production of CoQ10 declines. It also declines with chronic stress, toxin exposures, and certain medications. The decreased amount of CoQ10 in your cells contributes to the gradual loss of energy that most of us experience in our thirties and beyond. In today’s episode of my series I’m calling Health Bites, I am talking all about coenzyme Q10, also known as CoQ10—what it is, what it can do for us, and how to ensure we are getting enough of this critical nutrient. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What exactly is CoQ10? (3:42 / 1:32) Statins, muscle aches and pains, and CoQ10 production (4:20 / 1:55) How your body makes energy (5:14 / 2:40) The scientific discovery of CoQ10 (6:05 / 3:30) Benefits of CoQ10 (6:27 / 3:56) CoQ10 and heart health (7:40 / 5:10) Treating and preventing migraines with CoQ10 (8:51 / 6:18) CoQ10, insulin sensitivity, and blood sugar (10:02 / 7:29) Slowing and reversing Alzheimer’s and Parkinson’s disease (10:34 / 8:00) CoQ10-rich foods and supplements (11:30 / 8:58)

This episode is brought to you by Cozy Earth, InsideTracker, and Essentia. Have you ever wondered what makes some people extraordinary? Is it something special some people just have at birth? Or are we all born the same only to evolve into greater things? I’m learning that no matter what age or phase of life we are in, we have the ability to make choices that change our lives and the lives of others for the better. Finding a purpose greater than ourselves is a catalyst for that change. Today’s conversation with Lynne Twist is an inspiring one. We take a deep dive into creating a life of meaning and commitment, what that means for our identity, and the ripple effect it has throughout the world. Over the past 40 years, Lynne has worked with over 100,000 people in 50 countries in the arenas of fundraising with integrity, conscious philanthropy, strategic visioning, and having a healthy relationship with money. An author and speaker, she has presented for the United Nations Beijing Women’s Conference, State of the World Forum, Synthesis Dialogues with His Holiness the Dalai Lama, and the Governor’s Conference on California Women, among others. A recognized global visionary, Ms. Twist has been an advisor to the Desmond Tutu Foundation, and The Nobel Women’s Initiative. This episode is brought to you by Cozy Earth, InsideTracker, and Essentia. Cozy Earth makes the most comfortable, temperature-regulating, and nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community $200 off their Ultimate Plan, or 34% off any other plan, at insidetracker.com/drhyman until the end of the month. Right now you can get an extra $100 off your mattress purchase, on top of Essentia’s holiday sale, which will also take 25% off, plus receive two FREE organic pillows (a $330 value), when you visit myessentia.com/drmarkhyman. Here are more details from our interview (audio version / Apple Subscriber version): Having a purpose larger than ourselves (6:32 / 4:27) How Lynne’s father’s death informed her inner life (9:51 / 7:40) Lynne’s journey to becoming an activist and philanthropist (14:01 / 12:15) Lynne’s work and learning about money and wealth from Mother Teresa (19:13 / 16:58) The biology of altruism (34:34 / 30:35) What makes ordinary people extraordinary? (35:40 / 31:58) Learning from indigenous people (38:26 / 34:30) Why living a committed life is crucial to our human future (46:55 / 43:00) Why we can’t sacrifice ourselves for others (58:02 / 53:40) How to find your calling (1:02:34 / 58:33) Get a copy of Lynne’s book, Living a Committed Life: Finding Freedom and Fulfillment in a Purpose Larger Than Yourself, here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, Paleovalley, and Beekeeper’s Naturals. Environmental toxins can wreak havoc on your body. And our bodies can only handle so much. There is a threshold, and when it’s passed, toxins can’t effectively be processed out of the body and are left lingering. When our toxic load is maxed out we start to see symptoms and dysfunctions. In today’s episode, I speak with Dr. Casey Means, Harriet Washington, and Maggie Ward about reducing your toxic exposure, the compounded effect of toxic exposures, and more. Dr. Casey Means is a Stanford-trained physician, Chief Medical Officer and cofounder of metabolic health company Levels, an associate editor of the International Journal of Disease Reversal and Prevention, and a lecturer at Stanford University. Her mission is to maximize human potential and reverse the epidemic of preventable chronic disease by empowering individuals with tools that can facilitate a deep understanding of our bodies and inform personalized and sustainable dietary and lifestyle choices. Harriet Washington has been the Shearing Fellow at the University of Nevada's Black Mountain Institute, a Research Fellow in Medical Ethics at Harvard Medical School, a senior research scholar at the National Center for Bioethics at Tuskegee University, and a visiting scholar at DePaul University College of Law. She is the author of Deadly Monopolies, Infectious Madness, Medical Apartheid, and A Terrible Thing to Waste, a book that looks at the devastating consequences of environmental racism—and what we can do to remedy its toxic effects on marginalized communities. Maggie Ward, MS, RD, LDN, is the Nutrition Director at The UltraWellness Center. She holds a master’s degree in nutrition from Bastyr University and focuses on using whole foods for holistic nutrition therapy. In addition, she completed her requirements to become a registered dietitian at Westchester Medical Center in New York. This episode is brought to you by Rupa Health, Paleovalley, and Beekeeper’s. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Right now until November 30, Beekeeper’s is offering my community 30% off. You can receive this offer sitewide by going to beekeepersnaturals.com/hyman or use code HYMAN at checkout. Full-length episodes of these interviews can be found here: Dr. Casey Means Harriet Washington Maggie Ward

This episode is brought to you by Mitopure and Athletic Greens. Each of us is made up of an estimated 30 trillion cells, all of which work together in harmony to perform all of the functions necessary for us to survive from day to day and year to year. But sometimes cells go rogue and don’t conform to the normal cell life cycle. When that happens, we end up with cells in our body that start to cause damage. These rogue cells, called senescent or “zombie” cells, release inflammatory chemicals that contribute to all manner of health issues—osteoarthritis, high blood pressure, type 2 diabetes, and Alzheimer’s, to name just a few. In today’s episode of my series I’m calling Health Bites, I am talking all about zombie cells—what they are, how they develop, and how we can get rid of them. This episode is brought to you by InsideTracker and Athletic Greens. Mitopure is the first and only clinically tested pure form of a natural gut metabolite called urolithin A that clears damaged mitochondria away from our cells and supports the growth of new, healthy mitochondria. You can get 20% off right now at timelinenutrition.com/mark by using code MARK at checkout. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What are zombie cells and how do they develop? (4:00 / 1:14) The negative effects of zombie cells (4:53 / 2:39) How to get rid of zombie cells (7:06 / 4:08) Causes of zombie cells (8:19 / 5:08) Natural and pharmaceutical compounds that kill zombie cells (11:17 / 8:00) Lifestyle practices that reduce and kill zombie cells (15:24 /12:20)

This episode is brought to you by BiOptimizers, Rupa Health, and InsideTracker. If we want to age as well as possible, maintain function and strength, and stay independent as we age, there is a key area of our physiology that we need to pay attention to: muscle. Skeletal muscle is the currency of aging; it’s an essential lever in maintaining optimal metabolic health, reducing body fat, and supporting longevity. And a major piece of building and maintaining muscle is protein consumption—which is often a controversial topic in the nutrition space. Today on The Doctor’s Farmacy, I talk with Dr. Gabrielle Lyon about the science of muscle mass, protein sources, and healthy aging and how we can all pay attention to these things in our daily lives. Dr. Gabrielle Lyon is a Washington University fellowship-trained physician in Nutritional Science and Geriatrics and is board certified in Family Medicine. She is the founder of the Institute for Muscle Centric-Medicine™ and has a private practice that services the leaders, innovators, mavericks, and executives in their prospective fields. In addition, Dr. Lyon also works closely with Special Operations Military. Her goal is to change the paradigm of medicine from obesity-focused to muscle-centric and change the way we think about health and medicine with high scientific integrity. This episode is brought to you by BiOptimizers, Rupa Health, and InsideTracker. Magnesium Breakthrough really stands out from the other magnesium supplements out there. BiOptimizers is offering my community 10% off, so just head over to bioptimizers.com/drhyman with code drhyman. ​​Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): Why muscle is key to overall health and longevity (5:25 / 2:14) How much protein should you eat vs the government’s Recommended Dietary Allowance (RDA) (11:12 / 9:26) Essential amino acids, animal vs plant sources of protein, and building muscle (18:55 / 15:10) How much protein do you need to eat with each meal? (29:04 / 26:02) Research showing that dietary protein will reduce hunger and cravings (33:54 / 29:15) High-protein food sources (37:22 / 32:19) Is meat bad for your health? (39:38 / 34:44) Stimulating mTOR, our “longevity switch” (45:55 / 37:23) Muscle-centric medicine (54:50 / 50:08) Dr. Lyon’s daily diet and exercise routine (1:05:09 / 1:00:24) Check out Dr. Lyon’s podcast, The Dr. Gabrielle Lyon Show, here. Get her free protocol with a food guide and subscribe to Dr. Lyon’s newsletter at drgabriellelyon.com.

This episode is brought to you by Rupa Health, ButcherBox, and Essentia. Heart disease, cancer, and stroke are the leading causes of death—and premature death at that—in the US. These diseases all have several risk factors in common, like smoking, physical inactivity, and poor diet, which policy often views simply as personal choices. We need to begin looking at disease prevention beyond individual decision-making. In this podcast, I talk with Dr. Anand Parekh, Senator Bill Frist, and Dr. Dariush Mozaffarian on the need for government policymakers to address disease prevention. Dr. Anand Parekh is the Bipartisan Policy Center’s chief medical advisor, providing clinical and public health expertise across the organization, particularly in the areas of aging, prevention, and global health. As a US Department of Health and Human Services deputy assistant secretary for health from 2008 to 2015, he developed and implemented national initiatives focused on prevention, wellness, and care management. He is the author of Prevention First: Policymaking for a Healthier America. Senator Bill Frist is a heart and lung transplant surgeon and former US Senate majority leader. He led passage of the 2003 Medicare Modernization Act and the historic PEPFAR HIV/AIDS legislation that has saved millions of lives worldwide. As the founder and director of the Vanderbilt Multi-Organ Transplant Center, he has performed over 150 heart and lung transplants, authored over 100 peer-reviewed medical articles, and published seven books. Dr. Dariush Mozaffarian is a cardiologist, Dean and Jean Mayer Professor at the Tufts Friedman School of Nutrition Science and Policy, and professor of medicine at Tufts Medical School. He has authored more than 400 scientific publications on dietary priorities for obesity, diabetes, and cardiovascular diseases and on evidence-based policy approaches to reduce these burdens in the US and globally. He has served in numerous advisory roles, including for the US and Canadian governments.⁣⁣ ⁣ This episode is brought to you by Rupa Health, ButcherBox, and Essentia. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. For a limited time, when you sign up for ButcherBox, they will send you 2 pounds of 100% grass-fed, grass-finished beef free in every box for the life of your subscription PLUS $10 off at ButcherBox.com/farmacy. Get an extra $100 off your mattress purchase, on top of Essentia’s Black Friday sale, which will also take 25% OFF. Plus receive 2 FREE organic pillows (a $330 value) with your mattress purchase at myessentia.com/drmarkhyman. Full-length episodes of these interviews can be found here: Dr. Anand Parekh Senator Bill Frist Dr. Dariush Mozaffarian

This episode is brought to you by InsideTracker and Athletic Greens. While there are many reasons that could account for occasional sleepless nights or a few days of having trouble focusing on the job, if you find yourself having persistent sleep-related issues, it could be that your circadian rhythms are out of balance. So what can you do when your body’s internal clockwork gets off? In today’s episode of my series I’m calling Health Bites, I delve into circadian rhythms—what they are, why they’re important, and how you can reset yours when they become unbalanced. This episode is brought to you by InsideTracker and Athletic Greens. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community $200 off the Ultimate Plan or 34% off any purchase at insidetracker.com/drhyman until the end of the month. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What are circadian rhythms? (5:14 / 2:02) The science behind circadian rhythms (6:29 / 3:17) Why you should get 20 minutes of sunlight first thing in the morning (7:07 / 3:55) What throws off your circadian rhythms? (8:04 / 4:51) The impact of sleep medication on your circadian rhythms (9:29 / 6:20) Ways to reset your circadian rhythms (10:20 / 7:08) Mentioned in this episode The Circadian Prescription: Get in Step with Your Body's Natural Rhythms My Sleep Master Class Why We Sleep: Unlocking the Power of Sleep and Dreams

This episode is brought to you by Rupa Health, InsideTracker, and Cozy Earth. Trauma isn’t just psychological; it impacts us all the way down to our genes. And those epigenetic changes don’t just stay with us—they can be passed down through several generations. That means the trauma we may be working through isn’t just our own, it’s the stress and trauma of our parents, grandparents, and even great grandparents. I know this might sound bleak, but today’s conversation on The Doctor’s Farmacy with Dr. James Gordon is about healing from all types of trauma to find greater mind-body peace. Dr. James Gordon, author of Transforming Trauma: The Path to Hope and Healing, is a Harvard-educated psychiatrist, and the founder and CEO of the nonprofit Center for Mind-Body Medicine in Washington, D.C. Dr. Gordon is internationally recognized for using self-awareness, self-care, and group support to heal population-wide psychological trauma. He is a clinical professor at Georgetown Medical School and was chairman (under Presidents Clinton and G.W. Bush) of the White House Commission on Complementary and Alternative Medicine Policy. This episode is brought to you by Rupa Health, InsideTracker, and Cozy Earth. ​​Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Cozy Earth makes the most comfortable, temperature-regulating, and non-toxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Here are more details from our interview (audio version / Apple Subscriber version): How the war in Ukraine is affecting Ukrainians’ mental health (5:24 / 2:00) Recognizing trauma as a universal part of life (11:15 / 8:00) Epigenetics and generational trauma (13:35 / 9:44) Techniques Dr. Gordon uses to heal generational, cultural, and individual trauma (17:03 / 13:45) Healing America’s divisiveness (24:53 / 21:10) Integrating unnamed and underlying cultural trauma (36:36 / 32:25) Moving beyond the medical model when it comes to trauma (41:59 / 38:00) Identifying and healing personal trauma (42:41 / 39:08) Stories of transformation from Dr. Gordon’s work (55:00 / 50:52) The importance of healing oneself first (1:00:54 / 56:40) Learn more about Dr. Gordon at jamesgordonmd.com. To support his trauma healing work in Ukraine, visit cmbm.org and click DONATE.

This episode is brought to you by Rupa Health, Thrive Market, and Essentia. Food marketing and misguided dietary guidelines play a large role in the food choices we make. These foods are frequently devoid of nutritional value and, even worse, they are addictive and keep you going back for more. Our bodies are built and maintained by what we put in our mouths; we literally are what we eat. Unfortunately, that means the majority of people in our country are made of ultra-processed food-like substances that create disease. In today’s episode, I talk with Nina Teicholz, Michael Moss, and Vani Hari on the influence of food marketing and why the US government’s dietary guidelines may not be so healthy after all. Nina Teicholz is a science journalist and author of the New York Times bestseller The Big Fat Surprise: Why Butter, Meat, and Cheese Belong in a Healthy Diet, which upended the conventional wisdom on dietary fat—especially saturated fat—and spurred a new conversation about whether these fats in fact cause heart disease. Michael Moss, a New York Times investigative reporter turned food-focused journalist, Pulitzer Prize winner for Explanatory Reporting, and author of the #1 New York Times bestseller Salt Sugar Fat: How the Food Giants Hooked Us, as well as the book Hooked: Food and Free Will, focused around food and addiction. Vani Hari is the revolutionary food activist behind foodbabe.com, cofounder of organic food brand Truvani, New York Times best selling author of The Food Babe Way and Feeding You Lies. She has led campaigns against food giants like Kraft, Starbucks, Chick-fil-A, Subway, and General Mills that attracted more than 500,000 signatures and led to the removal of several controversial ingredients used by these companies. This episode is brought to you by Rupa Health, Thrive Market, and Essentia. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Thrive Market is an online membership-based grocery store that makes eating well convenient and more affordable. Join today at thrivemarket.com/hyman and you will receive $80 worth of groceries for free. Right now you can get an extra $100 off your mattress purchase, on top of Essentia’s Black Friday sale, the biggest sale of the year, which will also take 25% off, plus you’ll get 2 FREE organic pillows (a $330 value) with your mattress purchase. Go to myessentia.com/drmarkhyman to learn more. Full-length episodes of these interviews can be found here: Nina Teicholz Michael Moss Vani Hari

This episode is brought to you by Paleovalley and Athletic Greens. Heartburn and reflux are major problems for so many people. At least 10 percent of Americans have episodes of heartburn every day and 44 percent have symptoms at least once a month. So why are we suffering from reflux? What is the cause? Is it something we are doing or something we are eating? Is there some other factor that’s driving this epidemic? In today’s episode of my series I’m calling Health Bites, I discuss simple actions you can take to uncover the root cause of your reflux, the problem with acid-blocking drugs, and more. This episode is brought to you by Paleovalley and Athletic Greens. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): Common triggers of reflux (2:25 / 1:45) Getting to the root cause of your reflux (8:11 / 5:18) Supplements that can help with reflux (9:31 / 6:36) The problem with taking acid-blocking drugs (10:36 / 7:40) Tests you can get done through your doctor (11:07 / 8:11) Weaning off acid-blocking drugs (12:16 / 9:15)

This episode is brought to you by BiOptimizers, InsideTracker, and Rupa Health. I would eat a lot more fish if I knew it was free from toxins like heavy metals, PCBs, and other dangerous compounds. It’s an incredibly healthy protein source when we can eliminate these factors, but sourcing clean fish can be tough. Today, I’m taking a deep dive into the issues surrounding fish, what kinds we should be eating, and everything in between with James Arthur Smith. James Arthur began his journey with regenerative aquaculture as a teenager volunteering at the Nature Interpretive Center in Southern California, where he got first-hand experience with a steelhead trout breeding and hatchery program. For the past ten years, he lived aboard and sailed around the Pacific from San Francisco to Ecuador and the Galapagos Islands. Throughout that time, he’s been on a mission visiting ocean aquaculture farms, vetting claims, lab testing seafood, and connecting the best-in-class aquaculture projects with farm-to-table restaurants in California. In 2020 he founded SEATOPIA, a gourmet seafood subscription box now delivering certified mercury-safe seafood, carbon-neutral, direct to homes nationwide. Through SEATOPIA, he is endeavoring to scale a truly regenerative seafood supply chain and empower health-conscious consumers to directly support innovative aquaculture projects producing some of the healthiest protein on the planet. This episode is brought to you by BiOptimizers, InsideTracker, and Rupa Health. Magnesium Breakthrough really stands out from the other magnesium supplements out there. BiOptimizers is offering my community 10% off, so just head over to magbreakthrough.com/hyman with code hyman10. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Here are more details from our interview (audio version / Apple Subscriber version): Why wild fish is not necessarily better than farmed fish (7:06 / 3:35) Assessing the pros and cons of aquaculture (12:39 / 8:40) The types of fish I recommend to my patients (17:50 / 14:31) Destructive industrial fishing practices (18:14 / 14:46) The dangers of feedlot (or factory) fish (27:34 / 20:27) Creating regenerative aquaculture (34:12 / 29:13) Microplastics and fish consumption (41:15 / 36:29) Why I rarely eat tuna (52:48 / 48:00) Aquaculture policy efforts and challenges (1:02:59 / 57:38) Creating a healthy supply chain for aquaculture feed (1:07:10 / 1:02) Learn more about Seatopia.

This episode is brought to you by Rupa Health, InsideTracker, and Essentia. There are actually many proven benefits of medical marijuana when it’s used the right way. In fact, cannabis may be one of the oldest documented herbal medicines on earth. And the body has a remarkable built-in system of endocannabinoid receptors that pair with it to reduce pain, improve sleep, increase mood, reduce nausea, and much more. In today’s episode, I talk with Dr. Misha Kogan, Dr. Josh Axe, and Jamie Wheal about the many benefits of cannabis, and we take a look at how the body’s built-in endocannabinoid healing system works in tandem with this plant medicine. Dr. Mikhail “Misha” Kogan is the medical director of the George Washington University Center for Integrative Medicine and associate professor of medicine at the George Washington University School of Medicine. Dr. Kogan has recommended medical marijuana to thousands of patients and is a frequent lecturer on medical cannabis to professional audiences across the nation. Dr. Josh Axe is a certified doctor of natural medicine, a doctor of chiropractic, and a clinical nutritionist with a passion to help people get healthy by empowering them to use nutrition to fuel their health. He is the bestselling author of Keto Diet, Eat Dirt, and Collagen Diet and author of the book Ancient Remedies. He is also the cofounder of Ancient Nutrition, which provides protein powders, holistic supplements, vitamins, essential oils, and more to the modern world. Dr. Axe founded the natural health website DrAxe.com, one of the top natural health websites in the world today. Jamie Wheal is the author of Recapture the Rapture: Rethinking God, Sex, and Death in a World That's Lost Its Mind and the global bestseller Stealing Fire: How Silicon Valley, Navy SEALs, and Maverick Scientists Are Revolutionizing the Way We Live and Work and the founder of the Flow Genome Project, an international organization dedicated to the research and training of human performance. This episode is brought to you by Rupa Health, InsideTracker, and Essentia. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Right now you can get an extra $100 off your mattress purchase, on top of Essentia’s Black Friday sale of 25% OFF, plus you'll receive two FREE organic pillows (a $330 value) with your mattress purchase. Go to myessentia.com/drmarkhyman to learn more. Full-length episodes of these interviews can be found here: Dr. Misha Kogan Josh Axe Jamie Wheal

This episode is brought to you by ButcherBox and Athletic Greens. High blood pressure—medically known as hypertension—affects about 30 percent of adults. Left neglected, it can severely damage your quality of life and set the stage for heart disease, kidney complications, or a stroke. Conventional medicine typically treats hypertension with medications that are generally effective in reducing the risk of these complications. These medications frequently come with unintended side effects, however. The good news is the right foods and nutrients can dramatically lower blood pressure without the high costs and side effects of medications. In today’s episode of my series I’m calling Health Bites, I discuss the driving forces of hypertension and the Functional Medicine approach to treating it. This episode is brought to you by ButcherBox and Athletic Greens. ButcherBox makes it easy to get humanely raised meat and wild-caught, sustainable seafood by delivering it right to your doorstep. Right now, when you sign up at butcherbox.com/farmacy, ButcherBox will give you two pounds of ground beef FREE in every order for one whole year. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): Normal and optimal blood pressure levels (4:07 / 1:00) The conventional medicine approach to treating high blood pressure (4:44 / 1:34) Underlying causes of high blood pressure (5:34 / 2:04) Does salt really cause high blood pressure? (7:30 / 4:20) Diet and lifestyle strategies to normalize blood pressure (11:09 / 8:00) Supplements for lowering blood pressure (14:18 / 11:07) Exercise and blood pressure (14:40 / 11:30) Stress, sleep, and blood pressure (15:14 / 12:03) Mentioned in this episode UltraBroth Recipe 10-Day Reset Guide

This episode is brought to you by Mitopure, Rupa Health, and FOND Bone Broth. When we take a global bird's eye view of diets around the world, it’s clear that the Western diet makes humans sick. Any nation that has acquired our habits of eating highly-processed foods, rich in refined carbohydrates, fructose, and inflammatory fats, ends up metabolically unhealthy. Metabolic health is much more than just maintaining a healthy weight. It’s the sum of our cardiovascular, mitochondrial, liver, gut, and hormone function—and a poor diet impacts all of these systems for the worse. Today, I’m excited to talk to my friend and a physician who is an inspiration to me, Dr. Robert Lustig, all about fixing our metabolic health. Dr. Lustig is a neuroendocrinologist with expertise in metabolism, obesity, and nutrition. He’s the Emeritus Professor of Pediatrics in the Division of Endocrinology and a member of the Institute for Health Policy Studies at UCSF. He is also one of the leaders of the current “anti-sugar” movement that is changing the food industry, in part through his game-changing books. His latest work is Metabolical: The Lure and the Lies of Processed Food, Nutrition, and Modern Medicine. This episode is brought to you by Mitopure, Rupa Health, and FOND Bone Broth. Get 10% off Mitopure at timelinenutrition.com/drhyman when you use code DRHYMAN10 at checkout. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. To experience iFOND Bone Broth's amazing health benefits, go to fondbonebroth.com/drhyman and use code HYMAN20 to get 20% off your purchase. Here are more details from our interview (audio version / Apple Subscriber version): The real problem with the Western diet (7:50 / 4:50) Why fatty liver is so prevalent today (9:45 / 6:44) How glucose and fructose affect the body differently (14:38 / 12:07) Insulin resistance, mitochondrial dysfunction, and chronic disease (18:08 / 14:00) How to know if you have insulin resistance or metabolic syndrome (21:54 / 18:07) Why sugar, not salt, drives high blood pressure (34:54 / 29:27) Eight subcellular pathologies that underlie metabolic disease (49:53 / 39:02) Fixing your health with food (1:06:02 / 1:01:31 Four things in our food supply that damage mitochondria (1:07:52 / 1:03:20) How to fix our food system (1:12:46 / 1:08:10) Learn more about Dr. Lustig at robertlustig.com and get a copy of his book, Metabolical: The Lure and the Lies of Processed Food, Nutrition, and Modern Medicine, here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Ask A Cardiologist episode with Dr. Neel Patel. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, ButcherBox, and InsideTracker. In Western culture, we’ve gained a negative view of aging. But in other cultures around the world, aging is celebrated and embraced. That’s because we define difficult symptoms like aches and pains, cognitive decline, and so many others as “aging” when they’re actually signs of dis-ease that can be prevented and often even reversed. Fortunately, there is much we can do to change the trajectory of aging starting at a young age, or at any age. In today’s episode, I talk with Dr. David Sinclair, Dr. Frank Lipman, and Dan Buettner about all the ways to age better, from supplements to support mitochondria, to increasing muscle, to cultivating community, and more. Dr. David Sinclair is a professor in the Department of Genetics and codirector of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, where he and his colleagues study longevity, aging, and how to slow its effects. Dr. Frank Lipman is recognized as a vocal pioneer of integrative and Functional Medicine (or what he calls “Good Medicine”). Dr. Lipman is the founder of Eleven Eleven Wellness Center and the Chief Medical Officer at The Well. He is a sought-after international speaker and the bestselling author of six books: How to Be Well, The New Health Rules, Young & Slim for Life, Revive, Total Renewal, and his newest book, The New Rules of Aging Well: A Simple Program for Immune Resilience, Strength, and Vitality.⁣ Dan Buettner is an explorer, National Geographic Fellow, award-winning journalist and producer, and New York Times bestselling author. He discovered the five places in the world—dubbed Blue Zones—where people live the longest, healthiest lives. This episode is brought to you by Rupa Health, ButcherBox, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. ButcherBox makes it easy to get humanely raised meat and wild-caught sustainable seafood by delivering it right to your doorstep. If you sign up at butcherbox.com/farmacy, ButcherBox will give you two pounds of ground beef FREE in every order for one whole year. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Full-length episodes of these interviews can be found here: Dr. David Sinclair Dr. Frank Lipman Dan Buettner

This episode is brought to you by Rupa Health and Athletic Greens. Typically, the first thing we reach for to deal with acne is a lotion, potion, or cream to apply to the skin—and conventional medicine doctors frequently prescribe birth control pills. These approaches do not target the root cause of acne, however. A growing body of research suggests it’s not what we slather on our skin that matters most but rather what is going on inside our body. In today’s episode of my series I’m calling Health Bites, I talk about acne—the number-one skin condition in the United States—and its effects on not just millions of teenagers but an increasing number of adults. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): Common causes of acne (4:16 / 1:16) Foods to avoid if you have acne or are trying to prevent a breakout (5:34 / 2:34) The gut-skin connection (7:22 / 4:45) Considerations for using the birth control pill to treat acne (8:30 / 5:37) Dietary and lifestyle changes for reversing acne (9:30 / 6:30) Choosing skin-safe topical products (13:00 / 10:03) Mentioned in this episode Milk and Health Environmental Working Group’s Skin Deep Cosmetic Database

This episode is brought to you by Mitopure, BiOptimizers, and Beekeeper’s Naturals. If you’ve ever been curious about why you are the way you are, the Enneagram can provide some really interesting insights. Translating this ancient practice into modern life can help us understand our unique gifts and how we can best show up in the world. The Enneagram is a system of mapping nine ways of being, including personality and beyond. The teaching of the Enneagram—an ancient map of how we work—has a fascinating intersection with Buddhism—an ancient map of how the mind works. I couldn’t be more excited to sit down with my very good friend Susan Piver to explore this connection and learn more about using the Enneagram and Buddhism to create greater self-love. Susan Piver is the New York Times bestselling author of many books, including the award-winning How Not to Be Afraid of Your Own Life, The Wisdom of a Broken Heart, Start Here Now: An Open-Hearted Guide to the Path and Practice of Meditation, and The Four Noble Truths of Love: Buddhist Wisdom for Modern Relationships. Her newest book is The Buddhist Enneagram: Nine Paths to Warriorship. This episode is brought to you by Mitopure, BiOptimizers, and Beekeeper’s Naturals. Mitopure is the first and only clinically tested pure form of a natural gut metabolite called urolithin A that clears damaged mitochondria away from our cells and supports the growth of new, healthy mitochondria. Get 10% off at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Magnesium Breakthrough really stands out from the other magnesium supplements out there. BiOptimizers is offering my community 10% off, so just head over to magbreakthrough.com/hyman with code hyman10. Right now, Beekeeper’s Naturals is giving my community an exclusive offer. Just go to beekeepersnaturals.com/HYMAN and enter code “HYMAN” to get 25% off your first order. Here are more details from our interview (audio version / Apple Subscriber version): What is the Enneagram? (5:53 / 2:48) The problem with the self-help movement (10:59 / 7:56) When working on yourself is counterproductive (14:09 / 11:00) Releasing self-aggression (16:03 / 13:32) Three ways to work with difficult emotions (27:21 / 23:23) Bringing the Enneagram into Buddhist thinking (33:31 / 28:49) Finding your Enneagram type (35:04 / 30:23) How the Enneagram can help free us from our negative self-talk (50:04 / 45:20) Using tonglen meditation to deal with individual and global pain (54:22 / 50:42) Directing our minds to gratitude and openness (1:02:02 / 56:08) Get a copy of Susan’s book, The Buddhist Enneagram: Nine Paths to Warriorship, here, and find her online community, the Open Heart Project, here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content. Mentioned in this episode Beeya Wellness Seed Cycling

This episode is brought to you by Rupa Health, InsideTracker, and FOND Bone Broth. Omega-3 is a fatty acid your body uses in all kinds of ways. Its benefits for our body are hard to overstate. But unlike most fats, your body can’t manufacture omega-3. Instead, it’s an “essential nutrient,” which means the only way to get it is through your diet. In today’s episode, I talk with Paul Greenberg, Dr. Andrew Huberman, and Dr. Daniel Amen about the importance of essential fatty acids like omega-3 for sleep, brain and heart health, and more. Paul Greenberg is the bestselling author of Four Fish, American Catch, and The Omega Principle. A regular contributor to the New York Times and many other publications, Mr. Greenberg is the writer-in-residence at the Safina Center, a Pew Fellow in Marine Conservation, and the recipient of a James Beard Award for Writing and Literature. Dr. Andrew Huberman is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award in 2017, which is given to the scientist making the largest discoveries in the study of vision. Work from the Huberman Laboratory at Stanford University School of Medicine has been published in top journals including Nature, Science, and Cell and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets. Dr. Daniel Amen is a physician, double-board-certified psychiatrist, 12-time New York Times bestselling author, and founder and CEO of Amen Clinics, with 10 US locations. Dr. Amen is the author of many books including the mega-bestseller Change Your Brain, Change Your Life, as well as The End of Mental Illness, Memory Rescue, Healing ADD, and Your Brain Is Always Listening. His new book, You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type, is now available. This episode is brought to you by Rupa Health, InsideTracker, and FOND Bone Broth. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. To experience the amazing health benefits of FOND Bone Broth, go to fondbonebroth.com/drhyman and use code HYMAN20 to get 20% off your purchase. Full-length episodes of these interviews can be found here: Paul Greenberg Dr. Andrew Huberman Dr. Daniel Amen

This episode is brought to you by Thrive Market and Athletic Greens. For years well-meaning doctors, echoed by the media, have emphasized what they have long believed is the intimate link between cholesterol and death by heart disease. If only it were so simple! You may hope that if you monitor your cholesterol levels and avoid the foods that are purported to raise cholesterol, you’ll be safe from America’s number-one killer. The truth is much more complex. Cholesterol is only one factor among many—and it’s not even the most important one—that contribute to your risk of getting heart disease. In today’s episode of my series I’m calling Health Bites, I talk about why standard cholesterol testing is outdated and why cholesterol may not be the cause of heart disease. This episode is brought to you by Thrive Market and Athletic Greens. Thrive Market is an online membership-based grocery store that makes eating well convenient and more affordable. Join today at thrivemarket.com/hyman to receive a FREE gift worth $60. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What is cholesterol? (4:36 / 1:48) The myth around cholesterol and dietary fat (5:06 / 2:25) The biggest source of abnormal cholesterol is not fat—it’s sugar (7:43 / 4:58) How lifestyle, environmental influences, and genetics influence cholesterol (8:28 / 5:44) Key contributors to heart disease (11:05 / 8:19) Tests to determine your risk for cardiovascular disease (13:13 / 10:24) How to lower your risk of heart disease and fix your cholesterol (16:58 / 14:10) The benefits, side effects, and risks of taking statin drugs (18:30 / 15:53) Mentioned in this episode Cleerly Sleep-hygiene blogs

This episode is brought to you by Cozy Earth, InisdeTracker, and Rupa Health. If you or a loved one struggle with addiction, this is an episode you’re going to want to listen to. Many of our current pharmaceuticals stem from compounds discovered in plant medicines. And many beneficial plants that were discovered decades ago still have huge potential for changing modern medicine—ibogaine is one of them. Today on The Doctor’s Farmacy, I’m excited to sit down with Dr. Deborah Mash to discuss the use of the African plant ibogaine and its metabolite, noribogaine, in the treatment of addiction and how it could impact the devastating opioid epidemic. Dr. Deborah Mash is one of the world's foremost experts on ibogaine. She is the CEO and Founder of DemeRx Inc., a clinical-stage drug development company advancing ibogaine and its active metabolite noribogaine for the treatment of opioid use disorder. DemeRx has partnered with ATAI Life Sciences—a global biotech platform with a special focus on psychedelic medicine—to develop ibogaine for those suffering from opioid use disorder. Building on the extensive human data available around ibogaine, DemeRx and ATAI are conducting a Clinical Phase I/II trial in opioid-dependent patients. This landmark trial will advance screening procedures, dosing guidelines, and best practices for opioid withdrawal management and relapse prevention. This episode is brought to you by Cozy Earth, InisdeTracker, and Rupa Health. Cozy Earth makes the most comfortable, temperature-regulating, and nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Here are more details from our interview (audio version / Apple Subscriber version): The long history of ibogaine’s ethnobotanical and ethnopharmacological use (7:01 / 4:10) The power of ibogaine to reset opioid tolerance and bypass many withdrawal symptoms in a single dose (15:41 / 8:11) How ibogaine works (20:59 / 14:15) Using ibogaine to protect against future relapse (26:09 / 19:25) Efforts to understand the importance of ibogaine’s psychedelic effects (30:05 / 24:54) Assessing the success rates of recovery and relapse prevention from ibogaine treatment (37:49 / 34:02) Understanding the underlying drivers of addiction for better recovery and relapse treatment (41:46 / 37:55) The concept of “psychoplastogens” and turning on synaptic plasticity in the brain (51:44 / 47:52) Humanity’s relationship to plants and plant medicines (57:25 / 53:34) Risks associated with and considerations for seeking ibogaine treatment (1:03:24 / 59:37) Learn more about Dr. Mash’s work at demerx.com.

This episode is brought to you by Rupa Health, Paleovalley, and HigherDOSE. Gluten is one ingredient we all love in bread or our favorite pizza dough, but it’s often the cause of inflammation and leaky gut, which is implicated in so many health conditions such as IBS, skin problems, Hashimoto’s, high blood pressure, and more. And it is not just people with celiac disease who are affected. In today’s episode, I talk with Maggie Ward, Dr. Alessio Fasano, and Dr. George Papanicolaou about how gluten affects the gut and how to know if it's a problem for you. Maggie Ward, MS, RD, LDN, is the Nutrition Director at The UltraWellness Center. Maggie holds a master’s degree in Nutrition from Bastyr University, which focuses on using whole foods for holistic nutrition therapy. She completed her requirements to become a registered dietitian at Westchester Medical Center in New York. Prior to joining The UltraWellness Center team in 2008, Maggie worked at the Brooklyn Hospital Center in New York. Advancing innovation in research, clinical care, and education, Alessio Fasano, MD, has dedicated his life to improving the quality of life for people with celiac disease and other gluten-related disorders. He founded the Center for Celiac Research at the University of Maryland School of Medicine in 1996. In 2013, he moved the center to Massachusetts General Hospital and renamed it the Center for Celiac Research and Treatment. He is chief of the Division of Pediatric Gastroenterology and Nutrition at Massachusetts General Hospital for Children and a professor of pediatrics at Harvard Medical School. Dr. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is board certified in family medicine from Abington Memorial Hospital. Upon graduation from his residency, he joined the Indian Health Service. In 2000, he founded Cornerstone Family Practice in Rowley, MA. He began training in Functional Medicine through the Institute for Functional Medicine. In 2015, he established Cornerstone Personal Health—a practice dedicated entirely to Functional Medicine. Dr. Papanicolaou joined The UltraWellness Center in 2017. This episode is brought to you by Rupa Health, Paleovalley, and HigherDOSE. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Right now, get your own Infrared Sauna Blanket or Infrared PEMF Mat at HigherDOSE.com and use my exclusive promo code FARMACY15 at checkout to save 15% off. Full-length episodes of these interviews can be found here: Maggie Ward Dr. Alessio Fasano Dr. George Papanicolaou

This episode is brought to you by Rupa Health and Athletic Greens. Hidden inflammation is at the root of all chronic illness—conditions like heart disease, obesity, diabetes, dementia, depression, cancer, and even autism. So if inflammation is at the root of most modern diseases, how do we find the causes and get the body back in balance? First, we need to identify the triggers and causes of inflammation. Then we need to help reset the body’s natural immune balance by providing the right conditions for it to thrive. In today’s episode of my series I’m calling Health Bites, I am talking about inflammation, how it’s linked to everything from obesity to all of the chronic diseases of aging, and how to combat it. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What is inflammation, and why can it become so dangerous? (3:36 / 00:54) The problem with common treatments such as anti-inflammatory drugs and steroids (8:05 / 5:23) Testing to determine if you are suffering from hidden inflammation (9:40 / 6:58) The biggest drivers of inflammation (11:06 / 8:22) Steps to living an anti-inflammatory lifestyle (15:48 / 13:06) Environmental Working Group Gut Food

This episode is brought to you by ButcherBox, FOND Bone Broth, and InsideTracker. I know many of us can relate to feeling disconnected from each other, the natural world, and the things that really matter in life. So how did we lose our way and how can we make better sense of the world? It takes some inner work but also means cultivating truth and connecting with community, in order to reshape our narrative and change the collective conversation and state of the world. Today on The Doctor’s Farmacy, I have a deep conversation on rediscovering meaning with Jamie Wheal, about reclaiming our inner passion, courage, and conviction. Jamie Wheal is the author of Recapture the Rapture: Rethinking God, Sex and Death In a World That's Lost Its Mind and the global bestseller Stealing Fire: How Silicon Valley, Navy SEALs, and Maverick Scientists Are Revolutionizing the Way We Live and Work and the founder of the Flow Genome Project, an international organization dedicated to the research and training of human performance. This episode is brought to you by ButcherBox, FOND Bone Broth, and InsideTracker. ButcherBox makes it easy to get humanely raised meat and wild-caught, sustainable seafood by delivering it right to your doorstep. If you sign up at butcherbox.com/farmacy, ButcherBox will give you two pounds of ground beef for one whole year. FOND Bone Broth brews up the best bone broth I've ever tasted. To experience the amazing health benefits for yourself, go to fondbonebroth.com/drhyman and use code HYMAN20 to get 20% off your purchase. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from the episode (audio version / Apple Subscriber version): What does it mean to recapture the rapture? (8:43 / 3:40) Personal growth vs self-indulgence (10:33 / 7:44) How the foundations of our understanding of the world are collapsing and transforming (23:39 / 19:35) Finding meaning and purpose in our modern world (30:00 / 24:30) The power of healing in community (33:38 / 25:42) Using breathwork, embodiment, sexuality, substances, and music to help us reconnect to ourselves and each other (37:31 / 33:14) Applying the tools of Hedonic Engineering to real lives and relationships (57:16 / 53:10) Research Jamie conducted with real-life couples (1:09:24 / 1:05) Why we need ethical guidelines to steer through our own personal explorations (1:19:16 / 1:15:02) Ten ethical guidelines that Jamie developed (1:22:22 / 1:16:40) Get a copy of Jamie’s book, Recapture the Rapture: Rethinking God, Sex, and Death in a World That's Lost Its Mind, here.

This episode is brought to you by Rupa Health, InsideTracker, and Pique Life. Instead of using a pharmaceutical drug, what if your doctor knew how to look deeper to find out what is causing your depression, ADHD, or anxiety? While there is a time and a place for drugs, they can have significant side effects and may not be as effective at correcting an underlying imbalance in the body. Functional Medicine practitioners look at gut health, genes, diet, hormones, and so much more to create a thorough healing plan. In today’s episode, I talk with Dr. Uma Naidoo, Dr. George Papanicolaou, and Dr. Drew Ramsey about how diet and lifestyle can be both a cause of and treatment for depression and other mental health issues. Dr. Uma Naidoo is a Harvard-trained psychiatrist, professional chef, and nutrition specialist. In her role as a clinical scientist, Dr. Naidoo founded and directs the first hospital-based clinical service in nutritional psychiatry in the US. She is the Director of Nutritional and Lifestyle Psychiatry at Massachusetts General Hospital (MGH) and Director of Nutritional Psychiatry at the Massachusetts General Hospital Academy while serving on the faculty at Harvard Medical School. Dr. Naidoo is the author of This is Your Brain on Food. ⁣ Dr. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is board certified in family medicine from Abington Memorial Hospital. Upon graduation from his residency, he joined the Indian Health Service. In 2000, he founded Cornerstone Family Practice in Rowley, MA. He began training in Functional Medicine through the Institute for Functional Medicine. In 2015, he established Cornerstone Personal Health—a practice dedicated entirely to Functional Medicine. Dr. Papanicolaou joined The UltraWellness Center in 2017. Dr. Drew Ramsey is a psychiatrist, author, farmer, and founder of the Brain Food Clinic in New York City, offering treatment and consultation for depression, anxiety, and emotional wellness concerns. He is the author of three books, most recently the award-winning cookbook Eat Complete: The 21 Nutrients That Fuel Brain Power, Boost Weight Loss, and Transform Your Health. This episode is brought to you by Rupa Health, InsideTracker, and Pique Life. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Pique is offering up to 20% off plus free shipping on their Pu'er bundles at piquelife.com/farmacy. Full-length episodes of these interviews can be found here: Dr. Uma Naidoo Dr. George Papanicolaou Dr. Drew Ramsey

This episode is brought to you by Rupa Health and Athletic Greens. “Fatty liver” literally means your liver fills with fat, which paves the way for chronic disease and inflammation. Fatty liver is a dangerous yet misunderstood disease. It is also very common, affecting 90 million Americans alone. You need a healthy liver to combat toxic junk and chemicals in your environment. A healthy liver means your body stays healthy, you don’t get sick, and you maintain plenty of energy. A fatty liver, on the other hand, has numerous repercussions including inflammation, which triggers insulin resistance and prediabetes, meaning your body deposits fat in your liver and organs, including your belly (called visceral fat). Fatty liver can also lead to more serious problems including high triglycerides, low HDL (“good” cholesterol), and high amounts of small LDL (dangerous cholesterol particles that can cause heart attacks). Fatty liver also increases your heart attack risk. In today’s episode of my series I’m calling Health Bites, I am talking about how to identify if you have fatty liver, what’s causing it, and how to fix it. This episode is brought to you by Rupa Health and Athletic Greens. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What is fatty liver disease? (4:16 / 00:40) Causes of fatty liver disease (5:23 / 2:25) How to know if you have fatty liver disease (5:51 / 2:54) The dangers of fatty liver disease (6:57 / 4:06) Fructose and fatty liver (8:57 / 5:55) Foods to avoid and to eat to fix a fatty liver (10:31 / 7:42) Supplements to support the liver (12:41 / 9:44) Detoxifying, liver-repairing superfoods (13:54 /10:26)

This episode is brought to you by Cozy Earth, BiOptimizers, and InsideTracker. For decades, I’ve been on a mission to help my patients understand that weight loss is not about “calories in, calories out”. There are a multitude of factors that play into how our body makes, stores, and burns fat and the actual amount of calories we eat is one small drop in the bucket of our complex biology. Today, I’m excited to talk with Dr. Casey Means about the main drivers people face when struggling to lose weight and what we can do about them. Dr. Casey Means is a Stanford-trained physician, Chief Medical Officer, and Co-founder of metabolic health company Levels, an Associate Editor of the International Journal of Disease Reversal and Prevention, and a Lecturer at Stanford University. Her mission is to maximize human potential and reverse the epidemic of preventable chronic disease by empowering individuals with tools that can facilitate a deep understanding of our bodies and inform personalized and sustainable dietary and lifestyle choices. Dr. Means’ perspective has been featured in the New York Times, Wall Street Journal, Men's Health, Forbes, Business Insider, Techcrunch, Entrepreneur Magazine, Metabolism, Endocrine Today, and more. This episode is brought to you by Cozy Earth, BiOptimizers, and InsideTracker. Cozy Earth makes the most comfortable, temperature-regulating, nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Magnesium Breakthrough really stands out from the other magnesium supplements out there. BiOptimizers is offering my community 10% off, so just head over to magbreakthrough.com/hyman with code hyman10. ​​InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): The top reasons for resistance to weight loss beyond food, sleep, stress management, and exercise (5:41 / 2:30) Obesogens, obesity, and resistance to weight loss (11:41 / 8:50) Common sources of toxins in our daily lives (13:57 / 9:45) How toxins negatively affect our health (14:44 / 12:10) Why detoxification is an important component of weight loss (17:45 / 15:00) Limiting our toxic exposure (18:49 / 16:26) The role of micronutrients in resistance to weight loss (29:33 / 25:16) Tips for grocery shopping for micronutrients (40:02 / 35:50) The impact of light on our metabolism (47:29 / 43:14) Using a continuous glucose monitor to improve your metabolic health (55:36 / 51:35) For a limited time only, if you sign up for Levels at levels.link/HYMAN, you'll receive five exclusive longevity strategies from me and Dr. Casey Means.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on stopping stress with your vagus with Dr. Titus Chiu. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, Paleovalley, and InsideTracker. Your gut is your inner garden—the more good bugs you have in it the more likely it is to flourish. Our gut bacteria regulate many of our bodily functions, from creating vitamins to controlling our immune system, our brain function, and, of course, our metabolism and weight. They are critical to our long-term health. But even if you’re eating the right things, you may need some outside assistance maintaining plentiful and diverse gut bacteria. Probiotics help populate your gut with beneficial bacteria, improving your sleep, daily elimination, brain health, and so much more. In today’s episode, I talk with Dhru Purohit, Dr. Tracy Shafizadeh, and Dr. Elizabeth Boham about probiotics, the importance of the gut microbiome starting in infancy, and why you should work with a skilled practitioner to choose the right probiotic for you. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. Dr. Tracy Shafizadeh is leading the work in understanding the infant microbiome. She is a nutritional scientist who helps new and expectant moms learn about creating healthy gut bugs in their babies. Dr. Shafizadeh received her Ph.D. in nutritional biology from the University of California, Davis, and spends her free time "loving the guts" out of her two boys. Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing. This episode is brought to you by Rupa Health, Paleovalley, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Full-length episodes of these interviews can be found here: Dhru Purohit Dr. Tracy Shafizadeh Dr. Elizabeth Boham

This episode is brought to you by Beekeeper’s Naturals and Athletic Greens. Your brain is an organ that’s connected to everything else happening in your body. Most of us never learn how to manage our energy and bodies. Instead, we use drugs like sugar, caffeine, and alcohol to self-medicate and manage our energy and moods. We don’t connect our behaviors and choices with how we feel. Many of us get too little good food, nutrients, light, air, water, rest, sleep, rhythm, exercise, community, love, meaning, and purpose. We’re exposed to far too much poor-quality food, stress, toxins, and allergens. But even if you manage all those things correctly, you still might not be getting the right amount of certain nutrients that support your brain and body. That’s where supplements come in. In today’s episode in my series I’m calling Health Bites, I am talking about how to heal our broken brains with the right nutrients. The brain is resilient and can recover and heal when given the right conditions. This episode is brought to you by Beekeeper’s Naturals and Athletic Greens. Right now, Beekeeper’s Naturals is giving my community an exclusive offer. Just go to beekeepersnaturals.com/HYMAN and enter code HYMAN to get 25% off your first order. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): Things that damage our brain (3:48 / 1:18) The top nutrients we need to support our brain health: multivitamins, Omega-3 fatty acids, magnesium, vitamin D, folate, B6, and B12, and probiotics (6:17 / 2:55) The gut-brain connection (11:26 / 8:55) The role of glutathione in brain function and how to boost it (12:24 / 9:46) Supporting mitochondria for brain health (13:14 / 10:42) Calming nutrients to support the brain (14:13 / 11:42)

This episode is brought to you by Rupa Health, BiOptimizers, and InsideTracker. Our relationships affect our health and happiness. The problem is that we’re never taught how to seek, create, nurture, and assess our relationships the same way we do our careers and bank accounts. But the cost of bad relationships on ourselves and our society truly adds up. The relationships many of us grew up around and might consider “normal” are in fact dysfunctional, creating a negative cycle we often don’t even realize we’re in. So how can we find good love, create good relationships, and keep them? That’s what today’s conversation with Mia Lux is all about. Mia merges the playful and the profound—drawing on her experience as a start-up CEO, stand-up comedian, personal growth junkie, and recovering lawyer. For over 7 years, Mia has been an international host, comedian & facilitator, specializing in designing and facilitating top wellness/personal development experiences around the world. Now, Mia is channeling this in the name of love as the Co-Founder & CEO of La Vette, a radical new platform designed to rehumanize dating in the digital era. This episode is brought to you by Rupa Health, BiOptimizers, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Magnesium Breakthrough really stands out from the other magnesium supplements out there. BiOptimizers is offering my community 10% off, so just head over to magbreakthrough.com/hyman with code hyman10. ​​InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): How our relationships affect our health and happiness (6:01 / 2:25) Shifting away from dysfunctional relationships toward intentional relationships (7:49 / 5:04) Self-inquiry to support healthy love relationships (14:07 / 11:30) Identifying the unconscious beliefs driving us into relationships (19:05 / 15:37) Letting go of good love and conscious uncoupling (25:11 / 20:02) Scientific predictors of relationship success (27:18 / 23:52) Interpersonal skills to improve your dating life and relationships (31:59 / 26:37) Speaking your truth in relationships (38:47 / 33:40) Navigating the dangers of dating (40:18 / 36:10) The importance of vulnerability and authenticity in dating and relationships (48:17 / 45:35) Learn more about LaVette and try your first month free at lavette.love/drhyman.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, InsideTracker, and Pique Tea. Hair loss is a commonly experienced issue and often signals something deeper going on in the body. And as there are many different types of hair loss, there are also many various drivers of hair loss, including hormonal imbalance, metabolic dysfunction, or even autoimmune disease. This is why Functional Medicine practitioners look at gut and metabolic health, nutrient status, and much more to find the root cause of hair loss. In today’s episode, I talk with Dr. Elizabeth Boham, Dhru Purohit, and Dr. Cynthia Li about the many different types of hair loss and their associated underlying causes. Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing, she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. Dr. Cynthia Li received her medical degree from the University of Texas Southwestern Medical Center in Dallas. She has practiced as an internist in settings as diverse as Kaiser Permanente Medical Center, San Francisco General Hospital, and St. Anthony Medical Clinic serving the homeless. Her personal health challenges led her to integrative and Functional Medicine, and she currently has a private practice in Berkeley, CA. She serves on the faculty of the Healer’s Art program at the University of California San Francisco School of Medicine, and she is the author of Brave New Medicine: A Doctor’s Unconventional Path to Healing Her Autoimmune Illness. This episode is brought to you by Rupa Health, InsideTracker, and Pique Tea. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Pique is offering up to 20% off plus free shipping on their Pu'er bundles. Just go to piquelife.com/farmacy for up to 20% off plus free shipping. Full-length episodes of these interviews can be found here: Dr. Elizabeth Boham Dhru Purohit Dr. Cynthia Li

This episode is sponsored by Paleovalley and Pendulum. Thyroid disease affects one in five women and one in ten men, yet 50 percent of people with thyroid disease go undiagnosed. The main role of thyroid hormone is to stimulate metabolism, and it affects almost every function of the body. That’s why thyroid imbalance can cause so many different symptoms. In today’s episode of a new series called Health Bites, I discuss thyroid disease and why an out-of-whack thyroid can stall your metabolism and create many other problems. I also share why using a whole-foods diet, nutritional supplements, and optimizing thyroid hormone replacement is critical for addressing thyroid disorders. This episode is sponsored by Paleovalley and Pendulum. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20. Here are more details from the episode (audio version / Apple Subscriber version): What is the thyroid gland and how does it function? (4:38 / 1:42) Symptoms of hypothyroidism (7:05 / 4:11) Diagnostic testing to assess thyroid function (8:42 / 4:54) What causes thyroid problems? (10:22 / 7:30) My approach to healing hypothyroidism (14:58 / 10:20) Thyroid-supporting foods and foods to avoid (15:15 / 12:20) Supplements that support your thyroid (17:00 / 14:04) Thyroid hormone replacement (17:46 / 14:50) If you suspect you have hypothyroidism, take a thorough inventory of any of the symptoms mentioned in the podcast to see if you might be suffering from hypothyroidism. get a full-spectrum thyroid test that includes TSH, free T3, free T4, TPO, and antithyroglobulin antibodies. check for celiac disease with a celiac panel. consider heavy metal toxicity testing. check your vitamin D level. Mentioned in this episode Self-Assessment Tool within The UltraThyroid Solution Workbook (Download here) EWG.org

This episode is brought to you by Rupa Health, InsideTracker, and Cozy Earth. If you’ve ever wondered if supplements are worthwhile or just create expensive urine, this is the podcast episode for you. While I wish it wasn’t the case, I do believe we need supplements to make up for the nutrients we can no longer get through food alone. It’s extra important to note, though, that not all supplements are created equal. And please keep in mind they’re called “supplements” for a reason, not “replacements”—they are meant to supplement a healthy diet and lifestyle to provide the most impact. Today, I’m excited to take a deeper dive into this topic with one of my most trusted sources when it comes to nutrition and dietary research, Chris Kresser. Chris Kresser M.S., L.Ac. is the co-founder of the California Center for Functional Medicine, the founder of Kresser Institute, the host of the top-ranked health podcast Revolution Health Radio, the creator of ChrisKresser.com, and the New York Times best-selling author of The Paleo Cure and Unconventional Medicine. Chris is one of the most respected clinicians and educators in the fields of Functional Medicine and ancestral health and has trained over 2,000 clinicians and health coaches from over 50 countries in his unique approach. He has recently launched Adapt Naturals, a supplement line designed to add back in what the modern world has squeezed out and help people perform and feel their best. This episode is brought to you by Rupa Health, InsideTracker, and Cozy Earth. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Cozy Earth makes the most comfortable, temperature-regulating, and nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Here are more details from our interview (audio version / Apple Subscriber version): Do we really need to take supplements? (5:14 / 1:54) Why our food is less nutritious than it used to be (13:32 / 10:10) Can you really get your nutrients from food? (15:28 / 12:10) The prevalence of, and most common, nutritional deficiencies (16:27 / 13:35) Testing your nutrient levels (21:35 / 18:25) Symptoms of common nutrient deficiencies (29:03 / 25:05) Can you take too much or overdose on nutrients? (41:57 / 36:58) What to look for in a quality vitamin or supplement (51:37 / 47:10) What nutrients are provided by plant vs animal foods (59:41 / 55:06) The most nutrient-dense foods (1:10:23 / 1:05:45) Learn more about Chris at ChrisKresser.com and check out his new supplement line, Adapt Naturals.

This episode is brought to you by Rupa Health, ButcherBox, and Mitopure. Sleep is a keystone of health. Most people know they should get more high-quality sleep, but they don’t really know where to start. But understanding the way our brain and neurotransmitters work means we can hack our sleep to not just feel amazing but to level up our focus, skills, and knowledge. And it’s not all about what happens at night, either—getting the right exposure to light at the right times has a profound impact on our circadian rhythms and the way our bodies transition to sleep. In today’s episode, I talk with Dr. Roger Seheult, Dhru Purohit, and Dr. Andrew Huberman about why optimizing your sleep should be prioritized and how you can get better sleep. Dr. Roger Seheult is currently an associate clinical professor at the University of California, Riverside School of Medicine, and an assistant clinical professor at the School of Medicine and Allied Health at Loma Linda University. Dr. Seheult is quadruple board certified in Internal Medicine, Pulmonary Diseases, Critical Care Medicine, and Sleep Medicine through the American Board of Internal Medicine. He is also the cofounder of MedCram, an online medical education company that helps healthcare professionals and laypeople understand medical topics clearly. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. Dr. Andrew Huberman is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award in 2017, which is given to the scientist making the largest discoveries in the study of vision. His lab’s most recent work focuses on the influence of vision and respiration on human performance and brain states such as fear and courage. Work from the Huberman Laboratory at Stanford University School of Medicine has been published in top journals including Nature, Science, and Cell and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets. This episode is brought to you by Rupa Health, ButcherBox, and Mitopure. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. If you sign up at butcherbox.com/farmacy, ButcherBox will give you 2lbs of ground beef free for one whole year. Get 10% off at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Full-length episodes of these interviews can be found here: Dr. Roger Seheult Dhru Purohit Dr. Andrew Huberman

This episode is sponsored by InsideTracker and Athletic Greens. Believe it or not, the surface area of your small intestine, which is where your food is absorbed, is the size of a tennis court. Your small intestine is also the home of your gut-immune system, which accounts for about 60 percent of your total immune system. The lining of this sophisticated system is just one cell layer away from a toxic sewer where all of the bacteria and undigested food particles live in your gut. If that lining breaks down—from stress; too many antibiotics or anti-inflammatory drugs like aspirin or ibuprofen; steroids; intestinal infections; a low-fiber, high-sugar diet; alcohol; and more—your immune system will be exposed to foreign particles from food, bacteria, and other microbes. This, in turn, creates havoc that can lead to an irritable bowel and other system-wide problems including allergies, arthritis, and autoimmune and mood disorders. In today’s episode of a new series called Health Bites, I discuss how to heal irritable bowel syndrome (IBS) and upregulate your gut health, which is at the forefront of Americans’ most common health complaints. This episode is sponsored by InsideTracker and Athletic Greens. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What is irritable bowel syndrome? (4:05 / 1:12) Symptoms of IBS (4:30 / 1:35) Causes of IBS (4:54 / 2:00) Identifying food allergies as the potential cause of IBS (8:00 / 5:11) How gut imbalance leads to IBS (9:36 / 6:44) Diagnostic testing to access gut health (12:14 / 9:25) What is SIBO, how does it cause IBS, and how is it diagnosed? (15:20 / 12:29) Assessing if yeast overgrowth is causing your gut issues (15:58 / 13:05) Treating yeast overgrowth and SIBO (16:40 / 13:50) Strategies for rebooting the gut and restoring optimal gut health (17:44 / 14:55)

This episode is brought to you by Rupa Health, InsideTracker, and FOND Bone Broth. Why are we seeing more chronic disease, stress, obesity, addiction, and so many other states of illness than ever before, despite having the most advanced medical system in the world? Because we aren’t living in a natural and normal world. We’re actually having normal responses to our abnormal circumstances, many of which create trauma that gets stored in the brain and body. Today on The Doctor’s Farmacy, I’m honored to talk to my dear friend Dr. Gabor Maté about the myth of normal, and why doing the difficult work of uncovering trauma is essential for living our fullest expression of life. A renowned speaker and bestselling author, Dr. Gabor Maté is highly sought after for his expertise on a range of topics including addiction, stress, and childhood development. Dr. Maté has written several bestselling books, including the award-winning In the Realm of Hungry Ghosts: Close Encounters with Addiction, When the Body Says No: Exploring the Stress-Disease Connection, and Scattered: How Attention Deficit Disorder Originates and What You Can Do About It, and has co-authored Hold On to Your Kids: Why Parents Need to Matter More Than Peers. His latest book, The Myth of Normal: Trauma, Illness & Healing in a Toxic Culture was just released. This episode is brought to you by Rupa Health, InsideTracker, and FOND Bone Broth. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. To experience the amazing health benefits of FOND Bone Broth, go to fondbonebroth.com/drhyman and use code HYMAN20 to get 20% off your purchase. Here are more details from our interview (audio version / Apple Subscriber version): Uncovering my personal trauma history (6:42 / 3:50) Scientific evidence linking trauma and stress to physical and mental illness (14:38 / 11:45) Social determinants of health (16:34 / 14:15) Our crisis of separation, disconnection, and loneliness (20:25 / 18:00) The link between addiction, our profit-driven culture, and trauma (25:16 / 22:20) The myth of normal (31:07 / 26:33) Tools, therapies, and resources for your own healing (49:50 / 45:41) Treating trauma with plant medicines and psychedelics (55:40 / 51:16) The biology of psychology (1:10:46 / 1:06:20) Gabor’s vision for our society (1:31:42 / 1:25:48) Learn more about Gabor Maté at drgabormate.com and get a copy of his new book, The Myth of Normal—Trauma, Illness, & Healing In a Toxic Culture, here.

This episode is brought to you by Rupa Health, Thrive Market, and Levels. We’ve been told that cognitive decline is inevitable, but researchers are discovering that we have more power over our aging brains than we once thought. What we eat, what we think, and how we live have incredible influence over the health of our brains—and our entire bodies. In today’s episode, I talk with Max Lugavere, Dr. Christopher Palmer, and Dr. Daniel Amen about foods that improve brain health, the link between our metabolic health and brain health, choosing happiness, and so much more. Max Lugavere is a health and science journalist and the author of the New York Times bestselling book Genius Foods: Become Smarter, Happier, and More Productive While Protecting Your Brain for Life, now published in 10 languages around the globe. His sophomore book, also a bestseller, is called The Genius Life: Heal Your Mind, Strengthen Your Body, and Become Extraordinary. Max is the host of a number-one iTunes health and wellness podcast called The Genius Life. Dr. Christopher Palmer is a psychiatrist and researcher working at the intersection of metabolism and mental health. He is the Director of the Department of Postgraduate and Continuing Education at McLean Hospital and an assistant professor of Psychiatry at Harvard Medical School. For over 25 years, he has held leadership roles in psychiatric education, conducted research, and worked with people who have treatment-resistant mental illnesses. He has been pioneering the use of the medical ketogenic diet in the treatment of psychiatric disorders—conducting research, treating patients, writing, and speaking around the world on this topic. Dr. Daniel Amen is a physician, double board-certified psychiatrist, twelve-time New York Times bestselling author, and founder and CEO of Amen Clinics, with 10 US locations. Dr. Amen is the author of many books including the mega-bestseller Change Your Brain, Change Your Life, as well as The End of Mental Illness, Memory Rescue, Healing ADD, and Your Brain Is Always Listening. His new book, You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type, is now available. This episode is brought to you by Rupa Health, Thrive Market, and Levels. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. Join Thrive Market today at thrivemarket.com/hyman to receive an extra $80 in free groceries with your first order. Learn more about Levels by going to levels.link/HYMAN. Full-length episodes of these interviews can be found here: Max Lugavere Dr. Christopher Palmer Dr. Daniel Amen

This episode is sponsored by ButcherBox and Athletic Greens. Think of magnesium as the relaxation mineral. Anything that is tight, irritable, crampy, and stiff—whether it is a body part or even a mood—can be a sign of magnesium deficiency. This critical mineral is actually responsible for over 600 enzyme reactions and is found in all of your tissues—but mainly in your bones, muscles, and brain. You must have it for your cells to make energy, for many different chemical pumps to work, to stabilize membranes, and to help muscles relax. Yet, so many of us are deficient in this important mineral. In today’s episode of a new series called Health Bites, I discuss why magnesium deficiency is a huge problem, why most of us are deficient, how to identify if you are magnesium deficient, and what to do about it. This episode is sponsored by ButcherBox and Athletic Greens. ButcherBox makes it easy to get humanely raised meat and wild-caught, sustainable seafood by delivering it right to your doorstep. If you sign up at butcherbox.com/farmacy, ButcherBox will give you two pounds of ground beef free for one whole year. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, when you purchase AG1 from Athletic Greens, you will receive 10 free travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): Why magnesium deficiency is so prevalent (3:26 / 00:57) Signs of magnesium deficiency (4:11 / 1:48) Magnesium use in a traditional hospital setting (5:37 / 3:15) Testing your magnesium levels (7:26 / 5:02) Food sources of magnesium (7:51 / 5:27) Things that deplete magnesium in the body (8:11 / 5:50) Other vitamins and minerals needed to ensure adequate magnesium levels (9:22 / 7:02) How to stop magnesium depletion (9:33 / 7:10) Magnesium supplements (10:24 / 8:03)

This episode is brought to you by Rupa Health, Cozy Earth, and BiOptimizers. Polycystic ovary syndrome, or PCOS, affects 5 to 10% of women in their childbearing years. Despite the many women struggling with the difficult symptoms of PCOS, we still know little about it. Those symptoms can include irregular or missing periods, excessive hair growth or hair loss, acne, and weight gain. Sadly, the average woman with PCOS sees four doctors before receiving a diagnosis. Today on The Doctor’s Farmacy, I’m excited to talk to Dr. Heather Huddleston to dig into the nuances and research around PCOS. Dr. Huddleston is the founder of the UCSF Multi-disciplinary PCOS Clinic and Research Center. This clinic provides care via an integrated group of providers with expertise in reproductive endocrinology, dermatology, nutrition, and psychology. Through the associated research program, Dr. Huddleston oversees investigations aimed at advancing our understanding of how physical activity, depression, cognition, sleep, and metabolic health all contribute to the manifestations of PCOS. Dr. Huddleston is passionate about broadly improving the care of patients with PCOS and serves as a medical advisor to Allara Health, which is an all-in-one virtual care platform for people with PCOS. This episode is brought to you by Rupa Health, Cozy Earth, and BiOptimizers. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Cozy Earth makes the most comfortable, temperature-regulating, and nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Magnesium Breakthrough really stands out from the other magnesium supplements out there. BiOptimizers is offering my community 10% off, so just head over to magbreakthrough.com/hyman and use code Hyman10. Here are more details from our interview (audio version / Apple Subscriber version): Why PCOS often falls through the cracks in our siloed medical system (6:04 / 3:12) Symptoms of PCOS (7:34 / 4:50) Do we know the causes of PCOS? (9:18 / 6:26) Diet, nutrition, gut health, and PCOS (14:00 / 10:21) How inflammation affects and exacerbates PCOS (17:15 / 14:22) The five areas Dr. Huddleston addresses with PCOS patients (22:54 / 18:20) Therapies for and approaches to treating PCOS (25:29 / 20:45) Supplements for treating PCOS (30:37 / 26:19) How exercise and quality sleep can benefit PCOS patients (33:23 / 28:52) Measuring insulin levels and diagnosing insulin resistance (43:03 / 38:35) Learn more about Dr. Huddleston here. Learn more about Allara at allarahealth.com.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on Meal Planning Tips & Setting Up Your Kitchen for Optimal Health with functional nutritionist, Taylor Groff. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, Paleovalley, and InsideTracker. The most profound cases of healing are in people who refuse to give up. Even if they’ve found some things that improve their condition, they continue searching for new ways to feel better and better. This is how we break down walls in medicine. The Functional Medicine methodology is the same; there is no end to searching for what is underneath the symptoms. Functional Medicine healing protocols can ultimately help change the prognosis of so many conditions, including the autoimmune disease multiple sclerosis. In today’s episode, I talk with Dr. Terry Wahls and Dr. Todd LePine about using diet, meditation, and much more to reverse devastating autoimmune disease symptoms. Dr. Terry Wahls is a clinical professor of medicine at the University of Iowa. Her secondary progressive multiple sclerosis confined her to a tilt-recline wheelchair for four years, but she restored her health using a diet and lifestyle program she designed specifically for mitochondrial health and now pedals her bike to work each day. She is the author of The Wahls Protocol: How I Beat Progressive MS Using Paleo Principles and Functional Medicine, The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles, and the cookbook, The Wahls Protocol Cooking for Life: The Revolutionary Modern Paleo Plan to Treat All Chronic Autoimmune Conditions. Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine certified practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. This episode is brought to you by Rupa Health, Paleovalley, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Full-length episodes of these interviews can be found here: Dr. Terry Wahls Dr. Todd LePine Dr. Terry Wahls

This episode is sponsored by InsideTracker and Athletic Greens. Glutathione is the most important molecule you need to stay healthy and prevent disease—yet you’ve probably never heard of it. It’s the secret to preventing aging, cancer, heart disease, dementia, and more, and it is necessary to treat everything from autism to Alzheimer’s disease. The good news is your body produces its own glutathione. The bad news is poor diet, pollution, toxins, medications, stress, trauma, aging, infections, and radiation all deplete your glutathione levels. In today’s episode of a new series called Health Bites, I discuss what glutathione is, why it’s important, and tips to help you optimize your glutathione levels, improve your detoxification system, and help protect yourself from chronic illness. This episode is sponsored by InsideTracker and Athletic Greens. This Labor Day, InsideTracker will take 26% off their top-selling Ultimate Plan if you’re in the US or Canada. International customers can take $30 off a Blood Results Upload Plan. Just go to insidetracker.com/DrHyman. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from the episode (audio version / Apple Subscriber version): What is glutathione? (4:26 / 1:31) Diagnostic testing of glutathione levels (6:08 / 3:16) Why many people have a limited ability to detoxify (6:29 / 4:09) The three main ways glutathione protects against chronic illness (8:38/ 5:46) Foods that support glutathione production (10:53 / 8:00) How exercise boosts glutathione (13:23 / 10:30) Reducing toxic exposure (14:19 / 11:35) Supplementing with N-acetyl-cysteine, alpha lipoic acid, methylation nutrients (folate and vitamins B6 and B12), selenium, antioxidants (including vitamins C and E in the form of mixed tocopherols), and milk thistle to boost glutathione (14:45 / 11:50) Mentioned in this episode Environmental Working Group ewg.org

This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker. All living things are programmed with a certain lifespan, which can be dramatically different from species to species. Humans now, in general, live twice as long as our ancestors, thanks to environmental changes and advances in medicine. But most of us spend the last years of our lives without the quality of life we really want. We’ve come to identify a slew of symptoms and chronic diseases as a natural part of aging, but do they really have to be? Today I’m excited to talk to Dr. George Church all about the latest science on reprogramming our genes to extend our healthspan and lifespan. Dr. George Church is a professor of genetics at Harvard Medical School, a founding member of the Wyss Institute, and director of PersonalGenomes.org, the world’s only open-access information on human genomic, environmental, and trait data. Dr. Church is known for pioneering the fields of personal genomics and synthetic biology. He developed the first methods for the first genome sequence and his team invented CRISPR for human stem cell genome editing and other synthetic biology technologies and applications—including new ways to create organs for transplantation, gene therapies for aging reversal, and gene drives to eliminate Lyme disease and malaria. Dr. Church is the director of IARPA & NIH BRAIN Projects and the National Institutes of Health Center for Excellence in Genomic Science. He is the author of Regenesis. This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): The top things that prevent disease and enhance longevity (7:06 / 4:13) Defining aging as a disease and treating it as such (8:24 / 5:40) Reprogramming and repairing cells to a younger state (12:24 / 9:35) The future, and challenges, of delivering Yamanaka factors for cell reprogramming (15:05 / 11:50) Gene editing vs gene therapy (28:02 / 22:36) Using gene therapy to reverse disease and lengthen life span (34:44 / 30:55) Animal-to-human organ transplants (37:34 / 33:04) Can we live youthfully to 100 years old and beyond? (44:31 / 40:34) How much and what types of protein do we need for healthy aging? (50:30 / 45:50) Using gene editing to bring back mammoths to restore damaged ecosystems (1:00:53 / 56:50) Get a copy of George Church and Ed Regis’ book, Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves, here.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have. Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

This episode is brought to you by Rupa Health, InsideTracker, and Pendulum. The majority of foods on our market shelves contain insane amounts of added sugar. One of the most problematic of these sugars is fructose, which raises our levels of uric acid, a central player in the metabolic mayhem affecting so many of us. This doesn’t mean all foods containing fructose are bad. Like all parts of health and nutrition, there are nuances we need to consider to create optimal health. In today’s episode, I talk with Drs. David Perlmutter, Casey Means, and Richard Johnson about how fructose and uric acid impact our physiology, why measuring uric acid levels is so important, and how fructose impacts our energy. Dr. David Perlmutter is a board-certified neurologist and five-time New York Times bestselling author. He serves on the board of directors and is a Fellow of the American College of Nutrition. He is the author of Grain Brain among others, and his new book, Drop Acid, was just released. Dr. Perlmutter received his MD from the University of Miami School of Medicine, where he was awarded the Leonard G. Rowntree Research Award. Dr. Casey Means is a Stanford-trained physician, Chief Medical Officer, and cofounder of metabolic health company Levels, an associate editor of the International Journal of Disease Reversal and Prevention, and a guest lecturer at Stanford University. Her mission is to maximize human potential and reverse the epidemic of preventable chronic disease by empowering individuals with tools that can facilitate a deep understanding of our bodies and inform personalized and sustainable dietary and lifestyle choices. Dr. Richard Johnson is a professor of medicine at the University of Colorado in Denver and has been a practicing physician and clinical scientist for over 25 years. He is internationally recognized for his seminal work on the role of sugar, and its component fructose, in obesity and diabetes. His work has also suggested a fundamental role for uric acid (which is generated during fructose metabolism) in metabolic syndrome. He previously authored The Sugar Fix with Timothy Gower in 2008, and The Fat Switch in 2012. His new book, Nature Wants Us to Be Fat, was just released. This episode is brought to you by Rupa Health, InsideTracker, and Pendulum. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman. To receive 20% off your first purchase of Pendulum’s Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20. Full-length episodes of these interviews can be found here: Dr. David Perlmutter Dr. Casey Means Dr. Richard Johnson