Pharmacy to Dose: The Critical Care Podcast

ACORN: Rapid Reaction Special Guests: Michael Behal, PharmD, BCCCP Joanna Stollings, PharmD, FCCP, FCCM, BCPS, BCCCP Michael Behal joins me to review the recently published ACORN trial from JAMA. We highlight the background of antibiotic-associated AKI, review the trial methodology and results, dive into the supplement and talk about duration of treatment, empiric v. targeted treatment, have definitively answered this question or not, and much more. Joanna Stollings makes a special appearance highlighting her experience on the research group while also discussing the logistics of this innovative trial design. Reference List: https://pharmacytodose.files.wordpress.com/2024/01/acorn-rapid-reaction-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Pharmacy to Eat: Food Recommendations and Life Update HAPPY THANKSGIVING! 03:19 – Indianapolis: Nick Peters 04:50 – Boston: Grace Erdman 05:55 – New Haven: Steve Lemieux and Kelly Oldziej 08:30 – Buffalo: Nick Servati 10:33 – New York: Karen Berger and Peter Nikolos 12:58 – Philadelphia: Ashley Barlow, Brooke Barlow, Sara Groome, Alyssa Meester, and Todd Miano 19:31 – Maryland: Mojdeh Heavner and Amy Yeung 21:38 – Charleston: Melanie Smith Condeni 24:07 – Memphis: Morgan Jones 26:18 – Cincinnati: Chris Droege 30:00 – Chicago: Matt Rubertus 31:35 – Detroit: Zach Smith 32:57 – Texas: Josiah Smith and Matt Wanat 36:25 – Europe: Philip Jacobson 38:12 – Favorite meals: Brian Gilbert and Haley Peters 41:02 – Life update https://pharmacytodose.com/2023/11/23/pharmacy-to-eat-food-recommendations/ PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

2023 ACCP Annual Meeting Recap Conference Correspondent: Anthony Hawkins, PharmD, FCCM, BCCCP Anthony’s travel day, Dallas airport comparison and city review, poster hall likes/dislikes, unique and notable clinical sessions, favorite titles, Critical Care PRN business meeting highlights, award winners, FCCP awardees, correcting a last name mispronunciation, #MakePharmacyLessFormal and much more. https://pharmacytodose.com/2023/11/22/2023-accp-annual-meeting-recap/ PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

2023 ACCP Annual Meeting Day 1 & 2 Mini Recap Nick discusses his highlights, thoughts, and even suggestions from Day 1 & 2 of the 2023 ACCP Annual Meeting in Dallas, TX. https://www.accp.com/meetings/am23/index.aspx @PharmacyToDose [email protected] PharmacyToDose.com Learn more about your ad choices. Visit megaphone.fm/adchoices

AVP: All Vasopressin Podcast Special Guests: Seth Bauer, PharmD, FCCM, FCCP, BCCCP Gretchen Sacha, PharmD, BCCCP 05:42 – Historical use/mechanism of action 14:00 – Septic shock guideline recommendations 18:45 – When to add vasopressin? 26:55 – Vasopressin dosing 38:52 – Predicting vasopressin response 48:55 – Use in special populations 61:25 – Discontinuation 67:39 – Cost considerations 72:48 – Use in other shock states 77:00 – Future research/Take-home points Reference List: https://pharmacytodose.files.wordpress.com/2023/11/avp-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: Rivers EGDT in Sepsis Special Guest: Rob Maclaren, PharmD, MPH, MCCM, FCCP I’m joined by Rob Maclaren to discuss the 2001 NEJM study “Early goal-directed therapy in the treatment of severe sepsis and septic shock.” We discuss the historical care of sepsis, mortality rates prior to this study, and use of critical care bundles before highlighting all the findings from the Rivers EGDT in sepsis trial. Then we review if one component is more important than others, break down the bundle, is EGDT still recommended, and much, much more. Reference list: https://pharmacytodose.files.wordpress.com/2023/11/rivers-egdt-tow-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

2023 North American Congress of Clinical Toxicology (NACCT) Pharmacist-featured Research Highlights 02:36 – “Association between daily high temperature and copperhead envenomations reported to a regional poison center” ft. Jimmy Leonard, PharmD, DABAT 18:22 – “Persistent complications following snake envenomation: results of a specialized snake post-discharge clinic” ft. Erin Ryan, PharmD 31:56 – “Evaluation of large-scale, interactive simulation in poison management & drug abuse course” ft. Kristin Reinaker, PharmD, DABAT 44:43 – “A systematic review of phenibut withdrawal with a focus on complications, treatment strategies, and phenibut alone or polysubstance withdrawal” ft. Ryan Feldman, PharmD, BCPS, DABAT 61:33 – “Evaluation of the carbapenem-valproate interaction” ft. Nick Petrucelli, PharmD 70:40 – “The use of ertapenem for reducing toxic valproic acid concentrations” ft. Patrick Dougherty, PharmD, BCPS, BCEMP Link to view research poster PDFs: https://pharmacytodose.com/2023/11/03/2023-nacct-pharmd-research-highlights/ @PharmacyToDose PharmacyToDose.com [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

CRRT Trials of the Week: RENAL & IDEAL-ICU Special Guest: Linda Awdishu, PharmD, MAS Linda Awdishu joins me to highlight two landmark studies related to the use of continuous renal replacement therapy (CRRT) in the critically ill. We discuss renal replacement therapy, compare modalities, and review the history of CRRT as an introduction. Then we review two studies: “Intensity of Continuous Renal-Replacement Therapy in Critically Ill Patients: RENAL study” published in 2009 and “Timing of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis: IDEAL-ICU study” published in 2018, both in the New England Journal of Medicine. Would these findings be replicated in other populations, do we have answers about the most appropriate effluent rate and when to initiate CRRT in the critically ill, findings from both studies, future research priorities, and much, much more! References list: https://pharmacytodose.files.wordpress.com/2023/10/crrt-tow-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Pulmonary Hypertension Part II Special Guest: Zach Smith, PharmD, BCPS, BCCCP, FCCP 04:03 – Intro/Diagnosis/Classification 14:30 – Treatment overview 24:00 – CCB 30:30 – PDE5i/ERA/GCS 40:00 – Prostacyclins 46:40 – RV failure in the ICU 64:30 – Role of PharmD/Take-home points Reference List: https://pharmacytodose.files.wordpress.com/2023/10/pulmonary-hypertension-part-ii-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: AID-ICU Special Guest: Grace Erdman, PharmD Grace Erdman, 2023 Pharmacy to Dose Award Winner, joins to discuss “Haloperidol for the treatment of delirium in ICU patients: AID-ICU trial” published in NEJM in 2022. We review studies that led to the AID-ICU study, discuss difficulties with delirium research, deep-dive into the AID-ICU trial, compare treatment in hyper-, and hypoactive delirium, research priorities moving forward, and much more. Reference list: https://pharmacytodose.files.wordpress.com/2023/10/aid-icu-tow-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: SPLIT Special Guest: Anthony Hawkins, PharmD, FCCM, BCCCP Anthony Hawkins joins me to highlight the “Effect of a Buffered Crystalloid Solution vs. Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial” published in JAMA. We compare the composition of different crystalloids, review pertinent trials published prior to this study, discuss the findings from the SPLIT RCT, what is the best primary outcome in these studies, research on the horizon, questions to be answered, and much more. Reference list: https://pharmacytodose.files.wordpress.com/2023/10/split-tow-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: CRASH-3 Special Guest: Ruben Santiago, PharmD, BCPS, BCCCP Ruben Santiago joins me to discuss the landmark article “Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3)” published in Lancet. We review the history of TXA use in trauma, what the CRASH-3 study ultimately found, how does this compare to previous studies, what are guideline recommendations, applying this info in the viscoelastic testing era, and much more. Reference list: https://pharmacytodose.files.wordpress.com/2023/10/crash3-tow-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Literature Review Series July 2023 Special Guests: Chris Bollinger, PharmD, MBA Hannah Davis, PharmD 04:05 – Featured Articles 44:35 – Cardiology 60:30 – Hematology 65:20 – Pulmonary 76:00 – PharmD 82:27 – Grab Bag Reference List: https://pharmacytodose.files.wordpress.com/2023/10/july-lrs-2023-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: UFH v. LMWH for Trauma VTE Prophylaxis Special Guest: Brandon Hobbs, PharmD, BCPS, BCCCP, FCCM Brandon Hobbs joins to discuss the landmark article “A comparison of low-dose heparin with low-molecular-weight heparin as prophylaxis against venous thromboembolism after major trauma” published in the New England Journal of Medicine. We review the history of VTE prophylaxis in trauma, what this study ultimately found, how long did it impact practice, what regimen is guideline-recommended today, practices from other centers across the country, and much, more. Reference list: https://pharmacytodose.files.wordpress.com/2023/09/vte-ppx-tow-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Extracorporeal Cardiopulmonary Resuscitation (ECPR) Special Guests: Caitlin Brown, PharmD, BCCCP, FCCM Patrick Wieruszewski, PharmD, BCCCP 04:22 – Definition/History of use 06:48 – ECPR vs. ACLS 11:40 – ECPR research 22:00 –VA ECMO overview 24:02 – Ideal patients/Contraindications 30:52 – ECPR overview from presentation to cannulation 41:15 – Pharmacotherapy in longer ECPR cardiac arrests 49:00 – ECPR post-resuscitation care 50:42 – Guideline recommendations 52:50 – Post-cannulation acute complications 56:10 – ECMO-induced PK/PD changes 59:07 – Advice for new ECPR programs 62:20 – Pharmacist’s role/Take-home points ECPR: A Primer for Pharmacists https://pubmed.ncbi.nlm.nih.gov/37070401/ Reference List: https://pharmacytodose.files.wordpress.com/2023/09/ecpr-references.pdf Curious Boxwood Etsy Shop: https://www.etsy.com/shop/curiousboxwood PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: Impact of Pharmacists & MRC-ICU Score Special Guest: Andrea Sikora, PharmD, MSCR, BCCCP, FCCM Andrea Sikora joins me to discuss her study “Impact of Pharmacists to Improve Patient Care in the Critically Ill: A Large Multicenter Analysis Using Meaningful Metrics with the MRC-ICU Score” published in Critical Care Medicine. We review what the MRC-ICU scoring tool is, evidence up to this point, where it’s been implemented, what did this study show, where do we go from here, how to join the MRC-ICU investigator team, and much more. Reference list: https://pharmacytodose.files.wordpress.com/2023/09/mrc-icu-tow-references.pdf Andrea’s book: “Pay It Forward: A Map to Mentorship in Medicine” https://www.amazon.com/Pay-Forward-Map-Mentorship-Medicine/dp/1946665649 PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Acute Coronary Syndromes (ACS) Special Guest: Nick Servati, PharmD, BCCP 04:55 – Pathophysiology/Clinical presentation 12:40 – “MONA” myths 20:05 – P2Y12 pretreatment 24:25 – Thrombolytics in ACS 30:35 – Anticoagulation 38:55 – Vasopressors/Inotropes 49:50 – IV antiplatelet agents 60:10 – STEMI pharmacotherapy checklist 66:00 – Future research/Take-home points Reference List: https://pharmacytodose.files.wordpress.com/2023/09/acute-coronary-syndromes-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Literature Review Series June 2023 Special Guest: Beau Blake, PharmD 03:50 – Featured Articles 30:40 – Cardiology 43:10 – PADIS 48:15 – Prostacyclins 51:20 – Infectious Diseases 63:10 – PharmD 70:15 – Grab Bag Reference List: https://pharmacytodose.files.wordpress.com/2023/09/june-lrs-2023-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: Linezolid v Daptomycin in VRE BSI Special Guest: Nick Britt, PharmD, MS, BCPS, BCIDP Nick Britt joins to highlight his first-author research comparing the use of linezolid v. daptomycin for treatment of vancomycin-resistant Enterococcus bloodstream infection (VRE BSI) published in Clinical Infectious Diseases in 2015. We review what the standard of care was for treatment at this time, how this study became to be, covering this featured article and discussing outcomes/results, then reviewing studies published since, how we still use results from this study, and much, much more. Reference list: https://pharmacytodose.files.wordpress.com/2023/09/dapto-v-linez-vre-bsi-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

2023 Neurocritical Care Society Annual Meeting Pharmacist-featured research 02:24 – Multicenter comparison of the safety and efficacy of clopidogrel versus ticagrelor for neuroendovascular stents featuring Casey May, PharmD, BCCCP, FNCS 15:24 – Prevalence of augmented renal clearance in neurocritical care population: a prospective multicenter study (Neuro-ARC study) featuring Sherif Mahmoud, BSc (Pharm), MSc, PhD, FNCS 24:41 – Derivation and validation of an equation to predict free valproate concentration in intensive care patients featuring Ji Liu, PharmD, BCCCP 43:05 – Effect of IV push levetiracetam and lacosamide implementation on turn-around times and cost featuring Veronica Bonderski, PharmD, BCCCP 53:25 – Neurostimulant prescription rates in patients with neurologic injuries AND Statin effects on inflammatory biomarker concentrations in patients with mild traumatic brain injury: a potential target for intervention featuring Sulaiman Almohaish, PharmD, BCPS and Gretchen Brophy, PharmD, BCPS, FCCP, FCCM, FNCS, MCCM 66:20 – Effect of melatonin on the use of antipsychotic medications in the intensive care unit featuring Madeline Mitchell, PharmD, BCPS 77:10 – Pharmacists decrease number of protocol discordant four-factor prothrombin complex concentrate orders for oral anticoagulant-associated intracranial hemorrhage in a community emergency department featuring Ifoma Ofoegbuna, PharmD, BCCCP 84:12 – Clinical pharmacist-driven electronic data capture of medication administration records in the ELECTRO-BOOST multicenter study featuring Andy Webb, PharmD, BCCCP Link to research poster PDFs: https://pharmacytodose.com/2023/09/13/2023-ncs-pharmd-research-highlights/ PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

2023 Pharmacy to Dose Award Winner Celebration 08:04 – Deborah Wagner, Publication of the year winner 11:35 – Megan Rech, Mentor of the year winner 13:32 – Brian Gilbert, Conference speaker of the year winner 15:45 – Melissa Thompson Bastin, Preceptor of the year winner 18:14 – Alyssa Meester and Adam Smith, Tag Team Tandem of the year winner 21:54 – Grace Erdman, PGY2 resident of the year winner 24:45 – Ruben Santiago and Andy Webb, Co-Social media star winners 28:17 – Carolyn Bell, People’s Choice award winner 30:56 – Mojdeh Heavner, MVP award winner 34:06 – Rob Maclaren, Living legend award winner 2023 Award Winners: https://pharmacytodose.files.wordpress.com/2023/09/the-2023-pharmacy-to-dose-award-winners.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: Phenobarbital for Acute Alcohol Withdrawal Special Guest: Joseph Lam, PharmD Joseph Lam joins me to highlight the 2013 trial published in the Journal of Emergency: Phenobarbital for acute alcohol withdrawal: a prospective, randomized, double-blind, placebo-controlled study. Joe shares his experience in the trial and all he did behind the scenes. Plus, we discuss the role of phenobarbital at that time, what this study found, what do we still need to know on this topic, and much more. Reference list: https://pharmacytodose.files.wordpress.com/2023/09/phb-in-aws-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Arrhythmias in the Emergency Department Special Guests: Kyle DeWitt, PharmD, BCPS Lance Ray, PharmD, BCPS, BCEMP 05:30 – Intro/background 10:10 – Atrial arrhythmias 56:40 – EKGs/Ventricular arrhythmias 72:35 – Bradyarrhythmias/take-home points Reference List: https://pharmacytodose.files.wordpress.com/2023/09/arrhythmias-in-the-ed-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: ATHOS-3 Angiotensin II for the Treatment of Vasodilatory Shock Special Guest: Dr. Ashish Khanna, MD, MS, FCCP, FCCM, FASA Dr. Ashish Khanna joins me to highlight the ATHOS-3 trial, where Dr. Khanna is the principal investigator and first author of the NEJM publication. We discuss the history of angiogensin II, research prior to ATHOS-3, highlight findings from the ATHOS-3 trial, writing for NEJM, experience leading a large prospective RCT in the critically ill, what research do we have since this landmark publication, and much more. Reference list: https://pharmacytodose.files.wordpress.com/2023/09/athos3-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: Insidious Harm of Medication Diluents Special Guest: Carolyn Magee Bell, PharmD, BCCCP Carolyn Bell joins me to discuss her first author research study, the Insidious Harm of Medication Diluents. We review what the perception around balanced fluids was in 2016, advice for prospective research, ultimate trial take-aways, things she would do different, bribing other Pharmacists, and much more. Reference list: https://pharmacytodose.files.wordpress.com/2023/08/medication-diluent-trial-of-week-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Aneurysmal Subarachnoid Hemorrhage (aSAH) Part II Special Guest: Casey May, PharmD, BCCCP, FNCS 04:24 – Guideline overview 09:15 – Blood pressure management 22:03 – Nimodipine 31:15 – Antifibrinolytics 36:58 – Hyponatremia and adjunctive treatments 46:20 – Seizure prophylaxis 49:10 -- Cerebral vasospasm/DCI treatment 52:46 -- Gaps in guidelines, future trials, ideas for future studies 60:25 – Take-home points Reference List: https://pharmacytodose.files.wordpress.com/2023/08/asah-part-ii-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: Tamiflu Dosing Review Special Guest: Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM Melissa Thompson Bastin joins me to discuss her review on oseltamivir dosing in the critically ill. We give an overview of the H1N1 pandemic, treatment regimens we used in the past, findings from this review, present-day oseltamivir dosing, applying lessons learned from H1N1 pandemic to the COVID-19 pandemic, and much more. Reference list: https://pharmacytodose.files.wordpress.com/2023/08/tamiflu-dosing-trial-of-week-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Heart Failure with Preserved Ejection Fraction (HFpEF) and Guideline/Consensus Document Writing Special Guest: Dave Dixon, PharmD, FACC, FAHA, FCCP, FNLA, BCACP, CDCES, CLS 02:57 – Experience and advice with guideline/consensus document writing 19:40 – HFpEF definition, complications, acute presentation, and HFpEF mimics 36:17 – HFpEF GDMT treatment 61:50 – Future directions and take-home points Reference List: https://pharmacytodose.files.wordpress.com/2023/08/hfpef-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

ARDS Part II Special Guest: Steven Lemieux, PharmD, BCPS, BCCCP 03:45 – ESICM guidelines and ARDS definition 11:50 – Phenotypes and respiratory support 23:50 – Corticosteroids 34:40 – NMBA, pulmonary vasodilators, and VV ECMO 44:00 - Fun facts and take-home points Reference List: https://pharmacytodose.files.wordpress.com/2023/08/ards-part-ii-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: CATS Special Guest: Scott Benken, PharmD, MHPE, BCPS-AQ Cardiology, FCCM, FCCP Scott Benken joins me to discuss the upcoming 2023 Chicagoland Critical Care Conference before reviewing the 2007 CATS study which compares catecholamine vasopressors and inotropes in septic shock. We cover the history of septic shock treatment, review the study results, current guideline recommendations, and much more. 2023 Chicagoland Critical Care Conference registration link:https://appserv7.admin.uillinois.edu/FormBuilderSurvey/Survey/uic_college_of_pharmacy/continuing_education/critical_care_2023/Survey Reference list: https://pharmacytodose.files.wordpress.com/2023/08/cats-trial-of-week-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Trial of the Week: Unpeeling the Banana Bag Special Guests: Aaron Cook, PharmD, FCCP, FNCS, FKSHP, BCCCP, BCPS Alex Flannery, PharmD, PhD, FCCM, BCCCP, BCPS Listen to Aaron and Alex go into the history of this famous article, discuss how this paper, and how they still feel the impact years after publication. Flannery AH, Adkins DA, Cook AM. Unpeeling the Evidence for the Banana Bag: Evidence-Based Recommendations for the Management of Alcohol-Associated Vitamin and Electrolyte Deficiencies in the ICU. Crit Care Med. 2016 Aug;44(8):1545-52. https://pubmed.ncbi.nlm.nih.gov/27002274/ PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Rapid Reaction: MERCY Special Guests: Erin McCreary, PharmD, BCPS, BCIDP Jason Pogue, PharmD, BCPS, BCIDP 11:00 – Background, study methodology, and results 23:00 – MERCY deep-dive, discussion, and future considerations MERCY: https://pubmed.ncbi.nlm.nih.gov/37326473/ Reference List: https://pharmacytodose.files.wordpress.com/2023/08/mercy-rapid-reaction-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Literature Review Series May 2023 Special Guest: Kelly Oldziej, PharmD 05:00 – Featured Articles 36:20 – Cardiology 47:20 – Infectious Diseases 51:00 – Emergency Medicine 59:22 – PharmD 66:15 – Grab Bag Reference List: https://pharmacytodose.files.wordpress.com/2023/07/may-lrs-2023-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Amiodarone v. Lidocaine: Versus Series Special Guest: Matt Wanat, PharmD, BCPS, BCCCP, FCCM 05:50 – Out-of-hospital cardiac arrest 19:15 – In-hospital cardiac arrest 32:04 – Refractory ventricular arrhythmias 47:08 – Potpourri 52:26 – Closing statements 2023 Pharmacy to Dose Awards Ballot: https://forms.gle/9y2wTM8y8tgodvYUA Reference List: https://pharmacytodose.files.wordpress.com/2023/07/amiodarone-vs-lidocaine-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

COPD Special Guest: Ty Kiser, PharmD, FCCM, FCCP, BCCCP, BCPS 03:15 – Background & classification 07:10 – AECOPD 13:00 – Pharmacotherapy in AECOPD 32:40 – Maintenance medications 41:55 – Future research / wrap-up 2023 Pharmacy to Dose Awards Ballot: https://forms.gle/9y2wTM8y8tgodvYUA Reference List: https://pharmacytodose.files.wordpress.com/2023/07/copd-references-1.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

BP Control in Neurologic Emergencies Part II Special Guest: Andrew Webb, PharmD, BCCCP https://www.neurowiserx.com 02:25 – Antihypertensive treatment overview 10:02 – IV push agents 17:47 – Continuous IV agents 34:00 – Take-home points Reference List: https://pharmacytodose.files.wordpress.com/2023/07/bp-in-neurologic-emergencies-part-ii-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Blood Pressure Control in Neurologic Emergencies Part I Special Guest: Andrew Webb, PharmD, BCCCP https://www.neurowiserx.com 03:50 – Background/pathophysiology 11:30 – AIS & thrombolysis 20:10 – AIS & thrombectomy 39:35 – Spontaneous intracerebral hemorrhage Reference List: https://pharmacytodose.files.wordpress.com/2023/06/bp-in-neurologic-emergencies-part-i-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

ESOC 2023 Rapid Reactions: TIMELESS and OPTIMAL-BP Special Guest: Leslie Hamilton, PharmD, FCCP, FCCM, FNCS, BCPS, BCCCP 04:15 – TIMELESS trial 21:20 – OPTIMAL-BP trial Reference List: https://pharmacytodose.files.wordpress.com/2023/06/esoc-2023-rapid-reaction-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

2023 SAEM PharmD Research 02:10 – Emergency Medicine Resident Perceptions of the Educational Impact of Emergency Medicine Clinical Pharmacists with Francisco Ibarra, PharmD, BCCCP 12:10 – Impact of Emergency Medicine Pharmacists on Anticoagulation Reversal with Jaclyn Scalgione, PharmD, BCPS 24:25 – Incidence of Postintubation Hypotension after Rapid Sequence Intubation in Full vs. Reduced Dose Induction Agent with Alicia Mattson, PharmD, BCCCP 35:12 – Phenobarbital as an Adjunct to Benzodiazepines in the Setting of Alcohol Withdrawal with Amelia Slane, PharmD, BCPS 48:19 – Single Dose Aminoglycosides for Complicated Urinary Tract Infections in the Emergency Department with Jordan Jenrette, PharmD 61:53 – Effect of Intravenous vs. Oral First Dose Antibiotics in the Emergency Department on Hospital Admission with Jessica Pham, PharmD PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Rapid Reaction: INTERACT3 Special Guests: Keaton Smetana, PharmD, MBA, BCCCP, FNCS Todd Miano, PharmD, PhD, FCCM 04:05 – Background, methodology, and results 17:35 – Statistics consideration and breakdown 31:10 – Deep-dive and future considerations 2023 Award Nomination Link: https://t.co/G4NfEEBFaS INTERACT3: https://pubmed.ncbi.nlm.nih.gov/37245517/ Todd Miano Figures: https://pharmacytodose.files.wordpress.com/2023/06/interact3_slides.pdf Reference List: https://pharmacytodose.files.wordpress.com/2023/06/interact3-rapid-reaction-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Literature Review Series Apr 2023 02:45 – 6-pack of studies 18:16 – Neuro 23:06 – Heme 27:55 – Infectious Diseases 31:20 – PharmD 36:44 – Grab Bag Reference List: https://pharmacytodose.files.wordpress.com/2023/06/apr-lrs-2023-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Perioperative Emergencies: Part II Special Guests: Sara J. Hyland, PharmD, BCCCP Eric Johnson, PharmD, BCCCP Gourang Patel, PharmD, MSc, BCPS, BCCCP, FCCP, FCCM Rachel Wolfe, PharmD, MHA, BCCCP 2023 Award Nomination Form: https://forms.gle/5oRzFYoVyJdPNCDA6 04:10 – LAST 24:05 – Dantrolene 37:45 – Advice and Future Vision Reference List: https://pharmacytodose.files.wordpress.com/2023/06/perioperative-emergencies-part-ii-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Special Guests and Podcast Partners: Tori Arsenault, PharmD Brooke Barlow, PharmD Anthony Hawkins, PharmD, FCCM Sylvia Stefanos, PharmD 2023 Pharmacy to Dose Award Nomination Form: https://t.co/G4NfEEBFaS 03:30 – 2023 Pharmacy to Dose Awards Info 18:35 – Medical Social Media Tips/Tricks 43:55 – Picking a Topic for Residency Research Projects 69:30 – Teaching and Precepting at the Bedside PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Perioperative Emergencies: Part I Special Guests: Sara J. Hyland, PharmD, BCCCP Eric Johnson, PharmD, BCCCP Gourang Patel, PharmD, MSc, BCPS, BCCCP, FCCP, FCCM Rachel Wolfe, PharmD, MHA, BCCCP 05:55 – Perioperative Pharmacist Background/Roles & Responsibilities 34:30 – Cardiac Arrest in the OR 52:43 – Sugammadex Reference List: https://pharmacytodose.files.wordpress.com/2023/05/perioperative-emergencies-part-i-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Recap of 2023 EMPoweRx Conference Special guest: Jimmy Pruitt, PharmD, BCPS, BCCCP First, a behind the scenes discussion with Jimmy Pruitt on all that went into EMPoweRx 23 (03:36). Followed by a recap of the conference itself including: an Austin city review, discussion on the educational sessions, highlighting the virtual side of the conference, favorite slide of the day, and more (24:48). PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Literature Review Series Mar 2023 Special Guest: Brent Tucker, PharmD 06:00 – Featured Articles 35:30 – Sepsis 42:15 – Heme 46:35 – Infectious Diseases 56:40 – PharmD 63:30 – Fun Article of the Month Reference List: https://pharmacytodose.files.wordpress.com/2023/05/mar-lrs-2023-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Diabetic Ketoacidosis and Medicine in the Media Special Guest: Janice Tsui, PharmD, BCCCP, MS 05:00 – DKA guidelines and consensus statements 13:05 – IV fluids 19:45 – Insulin 27:40 – Treatment goals and transition 31:20 – Hypoglycemia prevention 35:00 – Electrolytes and acidosis 41:05 – Euglycemic DKA 43:40 – Role of Pharmacist and ultimate take-aways 48:47 – Medicine in the Media featuring Jimmy Leonard, PharmD, DABAT Reference List: https://pharmacytodose.files.wordpress.com/2023/05/diabetic-ketoacidosis-references-1.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Tenecteplase in Acute Ischemic Stroke Special Guest: Salia Farrokh, PharmD, BCCCP, FNCS 07:45 – Alteplase history and comparison 14:20 – Thrombolysis guidelines in AIS 19:15 – Tips for reading stroke literature 21:00 – Tenecteplase literature review 39:45 – Tenecteplase research-in-progress 42:30 – Thrombolytic-induced ICH management 46:25 – Arguments for and against Tenecteplase 51:30 – Advice when switching thrombolytics 58:20 – Ultimate take-aways Reference List: https://pharmacytodose.files.wordpress.com/2023/04/tenecteplase-in-acute-ischemic-stroke-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Acetaminophen Overdose Special Guest: Jimmy Leonard, PharmD, DABAT Poison Center: 1-800-222-1222 05:11 – Patient Case Intro 06:46 – Pathophysiology and Nomogram 21:55 – GI Decontamination 29:10 – Labs & Signs/Symptoms 35:55 – Historical Treatments 37:10 – N-acetylcysteine (NAC) 66:30 – Adjunctive Treatments 77:50 – Ultimate Take-Away Reference List: https://pharmacytodose.files.wordpress.com/2023/04/acetaminophen-overdose-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Literature Review Series Feb 2023 Special Guest: Rhea Soltau, PharmD 04:10 – Featured Articles 34:50 – Cardiovascular 51:32 – Neurology 55:00 – PharmD 74:10 – Fun Article of the Month Reference List: https://pharmacytodose.files.wordpress.com/2023/04/feb-lrs-2023-references.pdf PharmacyToDose.Com @PharmacyToDose [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices