Trial of the Week: CRASH-3
Ruben Santiago joins me to highlight the landmark Emergency Medicine article researching tranexamic acid in TBI patients, the CRASH-3 trial
Pharmacy to Dose: The Critical Care Podcast
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Show Notes
Trial of the Week: CRASH-3
Special Guest: Ruben Santiago, PharmD, BCPS, BCCCP
Ruben Santiago joins me to discuss the landmark article “Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with
acute traumatic brain injury (CRASH-3)” published in Lancet.
We review the history of TXA use in trauma, what the CRASH-3 study ultimately found, how does this compare to previous studies, what are guideline recommendations, applying this info in the viscoelastic testing era, and much more.
Reference list: https://pharmacytodose.files.wordpress.com/2023/10/crash3-tow-references.pdf
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