
Trial of the Week: SPLIT
Anthony Hawkins, our fluid steward, joins the podcast to highlight findings from the landmark SPLIT trial, a study researching the ideal crystalloid in the critically ill.
Pharmacy to Dose: The Critical Care Podcast
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Show Notes
Trial of the Week: SPLIT
Special Guest: Anthony Hawkins, PharmD, FCCM, BCCCP
Anthony Hawkins joins me to highlight the “Effect of a Buffered Crystalloid Solution vs. Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial” published in JAMA.
We compare the composition of different crystalloids, review pertinent trials published prior to this study, discuss the findings from the SPLIT RCT, what is the best primary outcome in these studies, research on the horizon, questions to be answered, and much more.
Reference list: https://pharmacytodose.files.wordpress.com/2023/10/split-tow-references.pdf
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