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Rapid Reaction: ACORN trial

Rapid Reaction: ACORN trial

Michael Behal and Joanna Stollings join me to discuss the ACORN trial, comparing the safety of cefepime and piperacillin/tazobactam, published in JAMA in October 2023.

Pharmacy to Dose: The Critical Care Podcast

January 19, 20241h 11m

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Show Notes

ACORN: Rapid Reaction

Special Guests: Michael Behal, PharmD, BCCCP

Joanna Stollings, PharmD, FCCP, FCCM, BCPS, BCCCP


Michael Behal joins me to review the recently published ACORN trial from JAMA. We highlight the background of antibiotic-associated AKI, review the trial methodology and results, dive into the supplement and talk about duration of treatment, empiric v. targeted treatment, have definitively answered this question or not, and much more.


Joanna Stollings makes a special appearance highlighting her experience on the research group while also discussing the logistics of this innovative trial design.


Reference List: https://pharmacytodose.files.wordpress.com/2024/01/acorn-rapid-reaction-references.pdf


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