The Lab Report

Shakira Niazi is the founder of Basil Seed Works – an organic basil seed product line featuring the superfood ZenBasil. As a refugee from war-torn Afghanistan who was later raised and educated in the US, Shakira’s path to becoming an entrepreneur is remarkable. Although she’s known for her work with Vita Water – helping to solve the world water crisis and providing water points to poor villages around the world, her current focus is to bring basil seeds from the Far East to the Western world. Basil seeds are a natural source of fiber, omega-3 fatty acids, vitamins, minerals, and antioxidants. In today’s show, Shakira Niazi tells us her inspiring story - from childhood refugee to being featured in Times Square. We also discuss the amazing health benefits of basil seeds and why they are the new superfood! Today on The Lab Report: 5:30 Meet Shakira Niazi and hear her amazing story 10:30 Changing courses through the pandemic 20:40 Health benefits of basil seeds 26:40 Hydrating and using basil seeds 28:45 ZenBasil vs. other basil seeds 30:45 Where to find ZenBasil 32:00 The Fireball Additional Resources: ZenBasil Genova Connect **PROMO CODE TheLabReport for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Dr. Stephanie Venn-Watson dedicated her life to public health and veterinary epidemiology. In studying dolphins, she discovered the first essential fatty acid to be found in over 90 years – C15:0 (pentadecanoic acid). Dr. Stephanie’s discovery and further research on C15:0 has uncovered some amazing cellular health benefits and significant potential for disease prevention. With this knowledge, Dr. Stephanie pivoted and founded fatty15 - a company that produces the world’s first, and only science-backed, patented C15:0 supplement. In today’s episode, we speak with Dr. Stephanie Venn-Watson about her latest research into the newly discovered essential fatty acid C15:0 and how supplementation with fatty15 could be a game-changer for cellular health. Today on The Lab Report: 4:45 Stephanie Venn-Watson on veterinary epidemiology and dolphins 10:15 Pentadecanoic acid (C15:0), dolphins, and disease 12:20 Food sources for C15:0 15:35 Essential fatty acid criteria 18:45 Cellular stability and pentadecanoic acid 21:10 Red blood cell membranes and testing 24:10 Iron and ferroptosis 28:00 Measuring cell fragility 31:30 Ferroptosis and inflammatory cascades 34:05 Fatty15 supplementation 39:10 The Fireball Additional Resources: fatty15 Genova Connect **PROMO CODE TheLabReport for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Methylation is a very important enzymatic reaction responsible for so many crucial metabolic processes. In a previous episode, we introduced the topic of methylation and the basics of this biochemical reaction. However, there are many subtle nuances to consider when assessing whether a patient’s methylation cycle is out of balance. Today, we dive a bit deeper into the biochemistry of methylation and peel back the layers to show how some of the specific biomarkers and backup pathways contribute to imbalance. And, what does that mean clinically? It may help to review our prior episode or use Genova’s Methylation Pathway Handout to follow along. Today on The Lab Report: 2:50 Quick review of the methylation cycle 4:45 The important relationship between choline and betaine 7:05 Logical Speculation: Why is the betaine: choline ratio associated with disease risk? 9:35 Dimethylglycine (DMG) 11:15 Sarcosine and the ‘SAM disposal chute’ 14:20 Glycine: What does it do? 16:55 Transsulfuration and glutathione 21:00 The multi-omics of the methylation panel 22:25 Question of the Day: What is the stability of measuring SAM and SAH? Additional Resources: Genova's Methylation Panel Dr. Michael Chapman's Methylation Webinar Genova Connect **PROMO CODE TheLabReport for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

We are honored to welcome Dr. Casey Means back to the show. She is not only a passionate advocate for metabolic health, but also a voice of reason amidst a broken healthcare system, a profound champion spreading the message of connectedness and fearlessness, and lastly a dear friend. Dr. Means’ new book “Good Energy – The Surprising Connection Between Metabolism and Limitless Health” is available now anywhere books are sold. In this episode, we talk to Dr. Casey Means about her new book “Good Energy” which outlines how to connect the dots in healthcare, the critical importance of metabolic health, and practical tips to change your life and create your own GOOD ENERGY. Today on The Lab Report: 3:10 The Amazing Dr. Casey Means on connection vs. siloes in medicine 8:45 Economics of the current healthcare model and outdated thinking 12:15 Longevity and biohacking – where have we lost our way? 19:55 Fear of death, control, and transcending the fear mindset 23:20 Fixing incentive structures of the healthcare system & food and farm industries 33:10 Practical tips and eating for GOOD ENERGY 40:55 Overcoming behavior change obstacles – listen to your body! 44:00 ROI in eating healthy whole foods 45:35 Life is miraculous, live in awe- not fear 48:05 The Fireball Additional Resources: Get your copy of Good Energy today! Casey’s Newsletter sign-up: https://www.caseymeans.com/newsletter Casey’s Social Media Platforms: Instagram: https://www.instagram.com/drcaseyskitchen/ Twitter: https://twitter.com/CaseyMeansMD TikTok: https://www.tiktok.com/@caseymeansmd YouTube: https://www.youtube.com/@CaseyMeansMD LinkedIn: https://www.linkedin.com/in/casey-means-md/ Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

The word ‘methylation’ has become somewhat of a buzz word in functional and personalized medicine. We’ve mentioned it several times throughout many episodes of The Lab Report – hard to avoid since it’s involved in just about every biological process. In today’s episode, we finally hit the topic of methylation head on and dive into the methylation cycle itself. What is it? Why should you care? Although biochemistry can be intimidating, listen as we simplify and demystify the steps involved. You may find it helpful to refer to a Methylation Pathway Chart while listening to this one! Today on The Lab Report: 2:00 What is methylation and why is it clinically important 5:30 Jumping into the biochemistry – metaphors to the rescue! 11:35 Homocysteine 14:00 The main pathway versus back up pathway 19:33 Transsulfuration 22:30 Multi-omics and the methylation cycle 27:50 Question of the Day “What does it mean if homocysteine is low?” Additional Resources: Genova's Methylation Panel Dr. Michael Chapman's Methylation Webinar Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Everest Goldstein is a board-certified Psychiatric Nurse Practitioner who is also certified in Functional Medicine and has an extensive background in integrative wellness interventions. She deeply cares about her patients and devotes her time to working closely with each of them to address their individual needs. Knowing the importance of the brain-body connection, Everest addresses the body as a whole to optimize health and wellness. In today’s episode, we dive into the root causes of mood disorders and psychiatric illness with Everest Goldstein. Everest discusses how nutrition, diet, and lifestyle can contribute to mental health and wellness. If you are struggling mentally, emotionally, or physically, Everest is here to help you regain your life. Today on The Lab Report: 4:30 Meet Everest Goldstein and hear about her passion for psychiatry 7:45 Everest’s unique approach to mental health 9:55 The debate of mental health root causes 12:15 Gut microbiome and the brain connection 16:50 Nutrition changes for better outcomes 20:00 Using the ketogenic diet in mental illness 23:50 Protein, amino acids, and neurotransmitters 26:00 The role for psychiatric medications 28:30 Coaching lifestyle changes and motivation 31:50 Therapy and counseling 35:12 The Fireball Additional Resources: Everest Functional Psychiatry and Wellness Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Berberine is an alkaloid compound that can be extracted from several plants. It is a widely used supplement in personalized medicine and is also beginning to get some traction within the conventional medicine space. Berberine is mainly used in the GI tract for its antimicrobial effects, but as it relates to gut health, that’s just the tip of the iceberg. What is even more fascinating is berberine’s vast systemic metabolic influences. In today’s episode, we dive into the wide array of berberine’s important effects. Not only on the gut, but also on detoxification systems, skin, eyes, lipid and blood glucose control, hypertension, and cardiovascular health. Today on The Lab Report: 4:00 Berberine – not an herb – where does it come from? 6:55 Overall gut modulator, skin health, and detox 13:05 Metabolic dysfunction – blood glucose, protein, lipids 14:50 Cardiovascular effects and heart health 16:00 Contraindications and safety considerations 18:00 What’s in a name? Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

For decades Dr. Nigma Talib has been helping patients using her clinical expertise in naturopathic medicine. Her contributions to the field are recognized globally. Dr. Nigma has authored best-selling books such as “Reverse the Signs of Ageing” and “Younger Skin Starts in the Gut.” She was one of the first pioneers to introduce vitamin supplements in the fashion industry and she’s responsible for the radiant, glowing skin of some of Hollywood’s most famous faces. In today’s episode, we are honored to meet Dr. Nigma Talib. We discuss her holistic approach to health and learn her skincare tips and tricks to reverse the signs of ageing. Today on The Lab Report: 3:50 Meet Dr. Nigma Talib 9:40 The importance of gut health in aging 12:40 Nutrition and skin 15:20 Dr. Nigma’s skincare products 16:55 Hydration 18:15 Light and radio frequency 20:00 Vampire facials and PRP 25:30 The Fireball Additional Resources: Dr. Nigma's website Shop Dr. Nigma's products Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Taylor Morgan Christie is a board-certified Physician Assistant, a registered dietitian nutritionist, and she’s double board certified in functional medicine through IFM and IFNA. So, it should come to no surprise that she can basically riff on any topic we throw at her. However, she has a special passion for treating thyroid disorders and helping her patients find whole wellness. She’s spent over a decade studying and mastering her clinical approach and today we learn all about it. On today’s episode, we talk all things thyroid with Taylor Morgan Christie, PA-C. Thyroid physiology, symptoms, medications, supplements, nutrition, labs, and more! Truly a masterclass for anyone suffering from thyroid disorders or clinicians not sure where to start. Today on The Lab Report: 5:00 Meet Taylor Morgan Christie and hear about her journey 10:35 Recognizing thyroid symptoms 12:20 Thyroid testing 101 - “normal” vs. optimal and timing med dosing 18:35 Choosing thyroid medications 23:04 Reverse T3 interventions 24:50 Proper absorption of thyroid medications 26:30 Nutrition and the thyroid 29:30 After optimizing - when to re-test labs? 34:05 The Fireball Additional Resources: MyWholeWellness.com Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Comprehensive Thyroid Assessment Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

If you’ve seen the Netflix documentary “The Social Dilemma,” you’ll recognize today’s guest. Dr. Anna Lembke is an addiction specialist from Stanford University, a New York Times best-selling author, and was featured on that Netflix special. Addiction takes many forms – not only alcohol and illicit drugs, but also social media, exercise, shopping, and workaholism. But, where’s the line between habit and addiction? What can we do to reset our brain chemistry? In this episode, Dr. Lembke explains dopamine’s role in our brain’s reward system. We discuss addiction in its many forms, social media, and strategies to rewire dopamine pathways. Today on The Lab Report: 3:00 Anna Lembke explains dopamine and the reward system 6:05 Dopamine hits in today’s society 10:40 Moderation vs. Abstinence 13:30 Social media and children 15:00 Does society award addictive behavior? 18:45 Long term dopamine dysfunction and Parkinson’s disease 22:00 Parenting in the digital age 27:20 The Fireball Additional Resources: annalembke.com Dopamine Nation Drug Dealer, MD The Social Dilemma Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Ok, well…. Today’s episode is a bit unique…. The intention was to discuss the important benefits of a trace mineral called boron. It is an important mineral, make no mistake. But, as we started recording, we got bored. Turns out talking about boron is kind of boring! So, we do hit the boron highlights, but then, in typical Patti & Michael fashion, we veer off into debate and discussion. The topic became the danger of misinformation by health influencers and how to remain skeptical. Today on The Lab Report: 3:10 Thirty seconds on boron 4:35 A dose of skepticism toward health influencers 7:55 Health information changing tides 11:20 Methylation SNPs and reductionism 15:30 GLP-1 agonists and total body systems 21:30 Wrap up – always be curious and skeptical Additional Resources: Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Genova’s nutritional testing offers precision results and personalized recommendations to create a nutritional treatment plan for optimal health and wellness. But for patients and clinicians, this can seem overwhelming when there is a significant amount of nutritional need. In addition to dietary counseling, clinicians often reach for supplements. VitaminLab is a premier supplement company in Canada that can customize results from the NutrEval and Metabolomix+ into as few pills as possible to help with patient compliance. Dr. Lydia Thurton is a naturopathic physician who works with clinicians through VitaminLab to help them through the process. In today’s episode, we talk to Dr. Lydia Thurton and discuss the process of customizing nutritional formulas, cautionary tales you should be aware of when choosing a supplement company, and the quality controls used by VitaminLab. Today on The Lab Report: 4:25 Meet Dr. Lydia Thurton and hear about her path to the supplement industry 7:30 Combining supplements into as few pills as possible 9:40 Pill fatigue and compliance 11:00 Line between optimizing diet vs. supplementation 13:00 Choosing where to get your supplements – VitaminLab quality controls 17:35 Lydia’s private practice – passion for women of color 20:10 Online Mental Health Facebook group 22:10 Where to connect with VitaminLab and Dr. Lydia 23:15 The Fireball Additional Resources: Genova Connect **PROMO CODE TheLabReport20 for 20% off your next purchase** Dr. Lydia's Thai Inspired Chicken Meatball Soup VitaminLab Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Cayenne pepper, derived from the Capsicum annuum plant, is a fiery herb renowned for its intense heat and vibrant flavor. It contains a compound called capsaicin which is not only responsible for its spicy punch, but also numerous health benefits. Beyond its culinary uses, cayenne is highly regarded for its medicinal properties in gut health, pain relief, and even cardiometabolic disease. In today’s episode, we turn up the heat as we delve into the fiery world of cayenne. From its origins to its culinary and medicinal uses, we’ll uncover the secrets and surprising health benefits of this spicy superstar. Today on The Lab Report: 3:20 Why are we talking about cayenne? 4:40 Ethnobotany of cayenne 8:30 Capsaicin, the heat, and substance P 9:50 Cayenne and metabolic syndrome 11:40 GI tract effects – how counterintuitive! 15:30 Cardiovascular disease and cayenne 16:40 Headaches and pain, topical cayenne – intranasal cayenne? WHAT! 18:55 Wilbur Scoville rabbit hole re: Scoville Units 22:50 What’s in a Name????? Additional Resources: Genova Connect **PROMO CODE TheLabReport20 for 20% off your next purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Genova’s Endo+ Profile is the first of its kind in hormonal health, offering the unique ability to test saliva, blood, and urine simultaneously. This flexibility lets providers create tailored hormonal profiles that reveal insights and connections between sex hormones, thyroid function, adrenal health, melatonin rhythms, and estrogen metabolism. While creating this product, we spent years scouring the research for the most up-to-date clinical information. Some of what we found, or more importantly didn’t find, calls into question what gets repeated in the echo chambers of functional medicine. Today is part 3 of our series where we challenge common doctrine in hormone testing. It’s good to be humble, take a fresh look at dogmatic concepts, and rethink what we thought we knew. Today on The Lab Report: 4:35 Endo+ - we are learning new lessons 6:05 Salivary testosterone in females 8:10 Urinary cortisol and the effects of dietary sodium 10:50 Steroidogenic pathway and aromatase enzymes 12:15 Ben Bikman, insulin resistance, and aromatase 13:50 Salivary collection – passive drool vs. devices 16:20 Serum hormone levels and BHRT 18:25 Salivary progesterone and stress 20:20 Estriol and estrogen metabolism Additional Resources: Endo+ Genova Connect **PROMO CODE TheLabReport20 for 20% off your next purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Foods come in and out of favor all the time. Eggs are good for you… no wait, they are bad… nope, good again – let’s not even discuss butter! There are many disease correlations related to specific foods and literature continues to evolve. One such focus is on red meat and its correlation to cardiovascular disease. But why? Is all red meat bad? Can you eat red meat and not increase heart disease risk? What about it should cause concern? Interestingly, the answer lies in the microbiome’s ability to metabolize the carnitine in red meat into a metabolite called trimethylamine (TMA). What happens from there is the key! But be warned, there is more to TMA than red meat and carnitine. Today we discuss TMA and how it becomes a cardiovascular risk factor (TMAO). We tell you about TMA’s many sources - besides red meat - and why you should care. Today on The Lab Report: 2:10 Food controversies 3:50 Break it Down: Trimethylamine (TMA) and trimethylamine N-oxide (TMAO) 6:40 TMAO, carnitine, and choline 10:00 Wait, which foods are actually the problem? 13:50 Red meat, TMAO, and cardiovascular risk 18:40 Dietary microbiome changes 20:05 Question of the Day: Which Genova profiles can help? Additional Resources: NutrEval Cardio Check Genova Connect **PROMO CODE TheLabReport20 for 20% off** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Patti & Michael are on the road! We recorded this unique episode from the Genova Diagnostics booth as a sponsor of the Metabolic Health Summit 2024 in Clearwater Beach, Florida. This conference brings together cutting-edge research, world-class speakers, and the leading experts in metabolic health. As you can imagine, Genova’s testing is a key element in getting to the root cause of metabolic disfunction and optimal health. The personalization of our testing and results can help guide therapeutic modalities that may not be so obvious. In today’s episode, you’ll hear Patti & Michael recorded live from the Genova booth at Metabolic Health Summit 2024. We recap some of the incredible clinical insights we gained from attending the lectures. We also chat live with some of our friends, old and new, to keep you up to date with the latest innovations in the metabolic health industry. Today on The Lab Report: 4:00 - Where are we? And, what is Metabolic Health Summit? 4:50 - Dr. Ben Bikman's Research on Adipose Tissue 6:45 - Pearls from Dr. Andy Galpin's Lecture 10:10 - Metabolic Psychiatry 13:00 - Using Specialty Testing for Metabolic Health 16:15 - Dr. Sheila Dean Stops By 17:15 - Dorian Greenow - Co-Founder of Keto-Mojo 24:15 - QOTD - Can you be metabolically health if you aren't on the ketogenic diet? Additional Resources: Metabolic Health Summit 2024 Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Dr. Bill Rawls was a practicing OB/GYN physician for decades before his health began to suffer and he was faced with the limitations of modern medicine. Embarking on his own health journey, he dove headfirst into holistic and herbal therapies and found ultimate wellness. Dr. Rawls now teaches and writes extensively about the power of herbal medicine. He’s written several books including Suffered Long Enough, Unlocking Lyme, and his latest book The Cellular Wellness Solution. Dr. Rawls even started his own herbal supplement and wellness company called Vital Plan. In today’s episode, Dr. Bill Rawls discusses his new book, The Cellular Wellness Solution, a fresh take on the critical role our cells play in unlocking wellness and supporting health. He champions the power of herbal medicine and explains why you should too. Today on The Lab Report: 4:00 Meet Dr. Rawls and hear his journey to herbal medicine 8:45 The Cellular Wellness Solution – 5 underlying cellular stressors 14:05 Microbial stress, chronic disease, and cancer? 21:10 Germ theory vs. Terrain theory 25:50 Difference between pharmaceutical drugs and herbs 32:15 Isolated constituents vs. whole herbs, adaptogens 33:20 Daily-use herbs, adaptogens, antimicrobials, anti-inflammatories 40:40 Current-day farming, primitive foraging, and the effects on our plants 44:30 Vital Plan and cautionary tales regarding supplement quality 50:20 The Fireball Additional Resources: Dr. Bill Rawls' website Vital Plan **PROMO CODE LabReport20 for 20% off your first order through May 1, 2024** The Cellular Wellness Solution Genova Connect **PROMO CODE TheLabReport20 for 20% off** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Dr. Taz Bhatia is a conventionally trained physician who has always been way ahead of her time. For years she’s been combining the best of modern science with eastern medical wisdom to help patients get to the root cause of chronic disease. As one of the OGs in functional and integrative medicine, Dr. Taz has become a national social media influencer, author, speaker, podcaster, television star, and go-to expert in women’s health. Her latest book “The Hormone Shift” offers patients the tools they need to navigate life’s hormone changes with ease. In today’s episode, we meet the one and only Dr. Taz Bhatia - a world-renowned expert in women’s health. Listen in as we discuss her brand-new book “The Hormone Shift.” Today on The Lab Report: 4:20 Meet the one and only Dr. Taz! 8:15 Eastern medicine influences 11:45 Advice for clinicians wanting to make the leap! 18:05 Women’s health and Power Types 22:25 The Hormone Shift and approaching hormonal imbalance 25:40 Diet and Lifestyle factors 29:25 Behavior change and the art of medicine 31:50 Taz on social media and YouTube 33:40 The Fireball Additional Resources: doctortaz.com The Hormone Shift Instagram: @drtazmd Genova Connect **PROMO CODE TheLabReport20 for 20% off** Endo+ Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Genova’s new Endo+ Profile is the first of its kind in hormonal health, offering the unique ability to test saliva, blood, and urine simultaneously. This flexibility lets providers create tailored hormonal profiles that reveal insights and connections between sex hormones, thyroid function, adrenal health, melatonin rhythms, and estrogen metabolism. While creating this product, we spent years scouring the research for the most up-to-date clinical information. Some of what we found, or more importantly didn’t find, calls into question what gets repeated in the echo chambers of functional medicine. Today is part 2 of our series where we challenge common doctrine in hormone testing. It’s good to be humble, take a fresh look at dogmatic concepts, and rethink what we thought we knew. Today on The Lab Report: 3:40 Reference ranges – population vs. healthy cohort 8:15 Reference ranges - comparing HRT dosages vs. actual symptoms 10:10 Making sense of urine hormone testing 12:50 Circulating hormone levels vs. tissue effects 18:15 Sex hormone binding globulin vs. free testosterone 20:15 Question of the Day What are the logistics of customizing the Endo+? Additional Resources: Endo+ Genova Connect **PROMO CODE TheLabReport20 for 20% off your next purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Hormones are complicated! The body makes dozens of hormones that influence each other. Fine-tuning that full hormonal symphony can lead to significant symptom improvement and well-being. Genova’s testing can help and the new Endo+ Profile is a great place to start. With this latest product upgrade, we’ve spent almost 2 years scouring the literature for the most up-to-date clinical information to help guide clinicians. However, while we were knee-deep in research and literature, we found ourselves with conflicting messaging and realized the echo chamber in personalized medicine might need to be re-examined. In today’s episode, we begin to challenge a few concepts in hormonal testing. Sometimes it’s good to be humble, take a fresh look at dogmatic concepts, and rethink what we thought we knew. Today on The Lab Report: 3:50 Endo+ Support Guide and literature diving 6:10 Salivary hormones – Why? How? What does it mean? 9:55 Super-secretors 12:45 Topical hormone replacement therapy and saliva 15:30 Bound vs. unbound, bioavailable vs. inert hormones 18:00 Megalin proteins and androgens 20:30 Free testosterone and the Free Hormone Hypothesis 22:00 Dear Sir……. What is Prestidigitation? Additional Resources: Endo+ Profile Genova Connect **PROMO CODE TheLabReport20 for 20% off your next purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

The subject of men’s health is often not discussed. A lot of men don’t proactively seek help for health concerns nor even want to admit there’s a problem. Well, today we’re going to change that. Ali Gilbert is a nationally recognized coach, lecturer, personal trainer, and expert in men’s health. Her Silverback Coaching programs help men from all walks of life, from CEOs to professional athletes and regular dads get to optimal physical and mental health. Today we meet Ali Gilbert and hear about her passion to help men get jacked, look great naked, optimize testosterone, and conquer nutrition. Today on The Lab Report: 5:05 Meet Ali Gilbert – convincing men she knows what she’s talking about! 9:15 Difference between coaching men and coaching women 11:40 Current state of men’s health 14:20 Addressing the mental and emotional needs of men 16:20 Athletes vs. non-athletes 19:30 Low testosterone symptoms 21:15 Testosterone replacement therapy 23:35 Natural ways to boost testosterone 26:20 Flipping the mindset switch 28:20 Nutrition – macronutrients and diet camps 33:25 Convincing men to ditch the dad-bod 37:25 What depletes testosterone? 38:04 How to work with Ali Gilbert 39:15 The Fireball Additional Resources: Ali-Gilbert.com Ali's Instagram @thealigilbert Genova Connect **Use Promo Code TheLabReport20 for 20% off your next purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

When it comes to holiday traditions, we think of decorating Christmas trees, baking cookies, the Elf on the Shelf, or lighting a menorah. But holiday traditions are far more unusual and diverse throughout the world. Some might really surprise you! On today’s episode, we touch on some unusual international holiday customs you’ve likely never heard while sprinkling in some clinical pearls. We also continue our podcast tradition of reading The Lab Report’s special rendition of ‘Twas the Night Before Christmas. Today on The Lab Report: 5:00 Kentucky Fried Christmas 7:00 The Christmas Pickle 8:55 Pooping logs, yule goats, & frankincense 14:30 Christmas disease game 17:30 Santa Claus towns 20:00 ‘Twas the Night Before Christmas Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

The body makes dozens of hormones that affect our health every day -sex hormones, thyroid, cortisol/stress hormones, melatonin etc. When hormones are out of balance, it can lead to symptoms like hot flashes, low libido, weight fluctuations, hair or skin changes, and many more. These symptoms can overlap since all hormones influence each other. That means, to get a full picture of hormonal health we need a broader lens. Listen in today as we discuss Genova’s Endo+ Profile – The first of its kind. Endo+ is a modular panel of testing that offers the unique ability to assess saliva, blood, and urine simultaneously. This flexibility allows providers to create their own profiles to reveal insights and connections between sex hormones, thyroid function, adrenal health, melatonin rhythms, and estrogen metabolism – and Genova synthesizes all of that information for you! Today on The Lab Report: 2:20 Hormones are complicated and interconnected 5:25 The hormone pyramid 8:35 Endo+ Profile – the complete picture 10:50 Break it Down - saliva, blood, urine 13:20 Variables in choosing sample types 18:00 Endo+ Testing options and information synthesis 20:20 Anabolic/Catabolic balance 21:10 Estrogen Metabolism 22:15 Add-ons 23:05 Endo+ puts it all together Additional Resources: Endo+ Profile Genova Connect **PROMO CODE TheLabReport20 for 20% off ** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.See omnystudio.com/listener for privacy information.

William Branum is a decorated Navy SEAL veteran with 26 years of active-duty service. Since leaving the military, William has dedicated his life to helping others through mentorship, coaching, speaking, and entrepreneurship. William’s expertise has been sought after by organizations ranging from small universities to Fortune 500 companies. He draws on his experiences to provide practical advice on how to cultivate a leadership style that inspires and motivates others, and how to develop the resilience needed to succeed in challenging environments. William founded the company ‘Naked Warrior Recovery’ to develop premium CBD products to support mental and physical recovery, through which he also supports several philanthropic causes for military and veterans’ mental health. On today’s episode, William Branum explains how the wisdom and life lessons he gained from his Navy SEAL training can apply to each of us in our life transitions, workplace environments, and personal interactions. William also talks about his CBD products and promoting mental health. Today on The Lab Report: 3:45 Meet the amazing William Branum and hear about his transition to civilian life 17:40 What is a Naked Warrior? 20:50 N.A.K.E.D., ego, and vulnerability 24:05 CBD products and Naked Warrior Recovery quality assurance 27:30 Cannabinoids, veterans’ mental health, and 22 to Zero 34:35 5 SEALS secrets to success and life lessons 39:30 Leadership and being the CEO of your life 51:00 The Fireball Additional Resources: Free e-book "5 SEAL Secrets" Naked Warrior Recovery Naked Warrior Apparel @william.r.branum Instagram Genova Connect **PROMO CODE TheLabReport20 for 20% off *** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Magnesium is a mineral that is crucially important to hundreds of biochemical reactions in our body. With gradual changes in soil, food processing, and the Standard American Diet, many of us just are not getting enough. So, what do we do? Dr. Robert Fredrickson has recently released a book all about this issue: Magnesium Answers: Unlocking the Secrets of Magnesium. As a functional medicine practitioner, he spent his career educating patients and doctors, but he also has a background as a product educator for major supplement companies. With that, Dr. Fredrickson is in a unique position to help us cut through the noise and understand the power of magnesium. On today’s episode, Dr. Robert Fredrickson talks about all things magnesium – what it does, why we should care, how much do we need, and how do we choose among all of the different forms of magnesium supplementation? Today on The Lab Report: 4:50 Meet Dr. Robert Fredrickson 9:30 How do we know if we’re not getting enough magnesium? 12:30 Magnesium in food and bioavailability 16:55 How much mag should we be getting? 18:15 Repleting mag and bowel tolerance 19:30 Measuring magnesium 22:10 Topical vs. IV vs. oral supplements 23:45 Types of magnesium supplementation 31:10 Magnesium toxicity, GI symptoms, Mag v. Calcium, IV mag 36:55 Fiber and magnesium connection 38:55 The Fireball Additional Resources: Fredrickson Health Solutions Magnesium Answers: Unlocking the Secrets of Magnesium Fredrickson Health Show Podcast Genova Connect **PROMO CODE - TheLabReport20 for 20% off Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Thanksgiving is a time to be mindful and reflect on our many blessings. During the holiday, many of us enjoy dinner with family and friends without stopping to consider the nutritional aspects of traditional dishes. Today, we discuss the important biochemical and nutritional benefits of Thanksgiving dinner items. We also talk about dealing with the stress of the holidays and the many reasons we are grateful. Today on The Lab Report: 3:30 Turkey and tryptophan – is it a thing? 5:15 Cranberry sauce apologetics 7:45 Potatoes! - and the microbiome 10:35 Green bean casserole, (fake) mushrooms, and onions 13:15 Hollandaise sauce? Gravy? Stuffing? Ummm…moving on 14:10 Pumpkin is a fruit 15:20 Moderation and modifying your dinner 16:15 Movement and mindfulness 19:20 Gratitude and community – Patti & Michael give thanks Additional Resources: Michael's Famous Green Bean Casserole? https://connect.gdx.net/ *PROMO CODE TheLabReport20 for 20% off** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

The immune system works tirelessly to maintain health and well-being. This formidable defense mechanism is comprised of a vast array of cells, tissues, proteins, and molecules that work together to identify and neutralize foreign invaders. The inflammation that ensues can be recognized by redness, pain, swelling, and heat. In order for this process to take place, the body needs to be able to identify what is ‘friend or foe’. But how? There are certain molecular patterns that our immune system recognizes as part of this surveillance and recognition. Some patterns are associated with pathogens - “pathogen-associated molecular patterns” (PAMPs). Others are associated with damaged cells (DAMPs) or lifestyle choices (LAMPs). In today’s episode, we do a quick refresher on adaptive and innate immunity. We also discuss some signaling molecules that trigger the inflammatory cascade – PAMPs, DAMPs, and LAMPs. Today on The Lab Report: 3:40 Break it down – innate vs. adaptive immunity 6:40 Pathogen-associated molecular patterns (PAMPs), Pattern Recognition Receptors (PRRs) 10:25 Sterile inflammation: damage-associated molecular patterns (DAMPs) 14:30 Lifestyle-associated molecular patterns (LAMPs) & chronic inflammation 18:25 Question of the Day How do we turn off the LAMPs? Additional Resources: Genova Connect *PROMO CODE TheLabReport20 for 20% off* Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

When it comes to changing the way the world views mental health, one voice remains consistent, science-based, empathetic, and passionate. That’s Brendan Vermeire. Brendan is dedicated to advancing the science of mental health dysfunction through his research, teaching, writing, and speaking. Here in functional and precision medicine, we are always looking for the root cause of any dysfunction. However, Brendan reminds us that mental health can have several root causes that need to be addressed and many of us are falling short when it comes to treating patients with mental illness. In today’s episode, we meet the amazing Brendan Vermeire. He talks about his passion for changing the way the world views mental health as we dive into some less obvious contributors and root causes. Brendan offers his approach to optimal mental well-being: metabolism, mindset, and the microbiome. Today on The Lab Report: 4:20 Meet Brendan Vermeire and hear why he’s so passionate about mental health 9:20 Connection between physiology and mindset 11:10 Gut-brain axis and the role of the microbiome 13:45 Go-to practical tips for optimizing the gut for mental health 17:00 Let’s talk about Methylation! 22:35 The exposome and toxins in mood disorders 27:00 Exercise, movement, and motivation 34:00 Meaning, purpose, and ‘the why’ 36:40 MetabolicSolutionsLLC.com 37:50 The Fireball Additional Resources: Metabolic Solutions Brendan's Instagram - @the_holistic_savage Genova Connect *PROMO CODE TheLabReport20 for 20% off* Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

The topic of intestinal parasites and their prevalence is hotly debated in functional medicine. Furthermore, the increasing trend of people performing a ‘parasite cleanse’ of the GI tract can be dangerous. Parasites are diagnosed in the stool using microscopy, direct exam, and PCR – but even then, not all parasites should be treated. Some can cause significant illness, yet others are not invasive, self-limiting, and considered nonpathogenic. In today's episode, we give a refresher course on gut parasites, discuss different ways to assess them, and introduce the topic of nonpathogenic parasites that don’t need to be treated. Today on The Lab Report: 3:50 Prevalence and transmission of parasites 6:45 What is a parasite? Are there nonpathogenic parasites? 8:10 3 main classes of parasites 10:20 Detecting parasites in the stool 13:10 Nonpathogenic parasites Chilomastix mesnili, Endolimax nana, Entamoeba coli, Entamoeba dispar, Entamoeba hartmanni, Entamoeba polecki, Iodamoeba buetschlii 16:50 Potentially pathogenic parasites 19:25 Question of the Day Why doesn’t Genova offer sensitivities for parasites on the GI Effects? Additional Resources: GI Effects Stool Profile Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

When it comes to assessing the microbiome, technology continuously evolves. With that, our understanding of the microbiome deepens. There is a lot of confusion out there regarding technology. Companies use marketing spin to lead you to believe the newest is the best when in fact, every technology has its strengths and weaknesses. No one method can capture the entire dynamic of the microbiome. Here at Genova, we use many methods to give you the most complete look at overall gut health. Today we simplify the science behind laboratory assays used to study the microbiome – culture, qPCR, metagenomics, and transcriptomics. Every method has its advantages and disadvantages. We’re cutting through the confusion with no marketing spin, just the facts. Today on The Lab Report: 3:30 So much confusion around laboratory methods - why should we care? 7:45 Culture technology is old but still so important 11:10 Conventional PCR and qPCR (aka Real-Time PCR) 15:40 Beware of these qPCR shortcomings 19:50 Next-Gen Sequencing 21:40 Metagenomics – not all labs are created equally!! 26:55 The vital role of taxonomy libraries 30:30 Transcriptomics and assessing RNA Additional Resources: GI Effects Microbiomix Genova Connect PROMO CODE: TheLabReport20 for 20% off Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Many clinicians learn about functional medicine and get very excited to start but just can’t figure out how to fit it into their practice or make the big leap away from conventional, insurance-based practice models. Dr. Michael Hilts figured it out. Dr. Hilts found out about the “Direct Primary Care” model which allowed him to fulfill his dream of bringing the best healthcare possible to his patients. In addition, his innovative strategies with outside imaging centers, laboratories, and pharmacies bring down the cost to patients in an almost unbelievable way! Could this be the answer to fixing our current healthcare system? Today we meet Dr. Michael Hilts who introduces us to the Direct Primary Care (DPC) practice model which is rapidly spreading across the country. You’ll hear about innovative ways he uses DPC and other strategies to bring back the spirit of primary care, challenge the current healthcare paradigm, and turn it on its head! Today on The Lab Report: 4:30 Meet Dr. Michael Hilts 5:50 What is Direct Primary Care and why did Dr. Hilts pivot? 12:20 Labs, medications, imaging = significant cost savings 16:10 The transition out of insurance-based conventional medicine 18:00 Incorporating functional medicine laboratory testing and success stories 24:00 Non-surgical sports medicine – ultrasound, prolo therapy, PFP 29:45 Work with Dr. Hilts 31:40 The Fireball Additional Resources: Hilts Direct Primary Care Genova Connect - (PROMO CODE: TheLabReport20 for 20% off GI Effects) Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

When it comes to sex hormones, progesterone is the unsung hero. It is actually the precursor to even making estrogen and testosterone. But progesterone is not just a precursor hormone. It is vital for maintaining pregnancy, helps with mood and sleep, works to help regulate the body’s water stores, and so much more. In today’s episode, we unpack all of the important functions of progesterone, break down its many fates of metabolism, and talk about ways to optimize your hormonal balance. Today on The Lab Report: 3:30 What is progesterone and where is it made? 5:15 The cholesterol connection 6:55 Circulation and many fates of metabolism 12:50 Functions of progesterone 15:05 High progesterone levels – symptoms and causes 17:05 “Progesterone steal” 20:00 Low progesterone levels – symptoms and causes 24:00 Symphony of hormones and metabolism 25:30 Treating low progesterone, root-cause, synthetic vs. bio-identical BHRT Additional Resources: One Day Hormone Check Rhythm Plus Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Have you ever said to yourself “Hey, I’m doing pretty good for my age”? Well, today’s episode will change everything you thought you knew about aging. Dr. Jeffrey Gladden is not only a renowned expert in longevity medicine but also a cardiologist, author, international speaker, and host of The Gladden Longevity Podcast. His personalized approach, ground-breaking therapies, and team of experts help guide you on a journey toward optimal health, longevity, and performance. Dr. Gladden’s latest book “100 is the New 30 – How Playing the Symphony of Longevity Will Enable Us to Live Young for a Lifetime,” outlines a roadmap to boundless energy while shattering the limitations of traditional aging beliefs. Today, Dr. Jeffrey Gladden explores the deep dimensions of longevity, the vital role of life energy and purpose in the aging process, and how to embark on your own ‘Hero’s Journey’ in living young for a lifetime. Today on The Lab Report: 3:30 Meet Dr. Jeffrey Gladden and hear his personal journey to longevity medicine 10:40 The Hero’s Journey and rethinking the aging process 15:00 Start with your pain point 17:15 Aging is exponential – not linear 21:00 How quickly can we alter aging? 23:00 Testing, supplements, diet & lifestyle 26:00 How to use Diet as a tool 28:40 The future of longevity medicine 30:45 Where you can go for more information 32:00 Physical work vs. mindset 35:00 The Fireball Additional Resources: Gladden Longevity Gladden Longevity Shop **USE PROMO CODE “GENOVA15” for 15% off thru 10/31/23 Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

When people hear the word ‘cannabinoid’, what usually comes to mind is marijuana (also known as cannabis) or CBD oil (cannabidiol). But did you know, the body creates its own natural cannabinoids using the endocannabinoid system? This endocannabinoid system is a mysterious and complex interplay of chemical messengers throughout the brain and body which in essence contributes to our body’s homeostasis. It regulates a broad array of physiological processes including pain, mood, sleep, inflammation, appetite, and more. Rather than relying on marijuana or CBD products, Dr. Joe Feuerstein teaches that there are ways to boost the endocannabinoid system naturally. As a nationally recognized and award-winning physician and researcher in the field of botanical medicine and nutrition, Dr. Joe has co-written a best-selling book on how to do just that. Today Dr. Joe Feuerstein tells us what the endocannabinoid system is and why you should care. He also outlines various herbal and natural ways to boost the endocannabinoid system for optimal health. Today on The Lab Report: 4:15 Meet Dr. Joe Feuerstein and hear about his amazing career 10:50 What are cannabinoids and why should we care? 14:05 Natural drivers to optimize the endocannabinoid system 19:30 The interaction between the HPA axis and the endocannabinoid system 21:00 Anecdotal improvements using the Cannabinoid Cookbook 23:00 Omega-6’s, anandamide and 2-AG, ‘cannabinoid resistance,’ chocolate 26:00 Gut-brain axis and the endocannabinoid system 27:40 Endocannabinoid deficiency, Cannabinoid Cookbook, Condition Kitchen 30:50 Using GI Effects actionable intelligence for microbiome modulation 39:20 Joe’s take on trendy diets 42:45 Where can we go to follow and work with Dr. Joe 44:45 The Fireball Additional Resources: Dr. Joe Feuerstein's website The Cannabinoid Cookbook Dr. Joe's Man Diet Dr. Joe's YouTube channel Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Many of us think of adipose tissue as just a place to store excess fat to be used for energy. However, adipose tissue is very biologically active and secretes some important hormones and mediators called adipokines. These messengers help regulate glucose and lipid metabolism, control hunger, and affect insulin levels. That being said, ALL of our hormones work together like a symphony – cortisol, thyroid hormones, sex hormones, and don’t forget the adipokines. In today’s episode, we discuss important bioactive messengers created by our fat tissue (leptin and adiponectin), how they affect us systemically, and strategies to optimize them. Today on The Lab Report: 3:40 Adipose tissue, adipokines, and types of fat 7:40 What are adipokines? 10:25 Adiponectin does great things 13:00 How to increase adiponectin 14:20 Better Know a Biomarker – Leptin! 17:40 Obesity and leptin resistance 19:25 Treating leptin resistance 21:35 Leptin vs. ghrelin 23:15 Adiponectin/leptin ratio Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

The commensal bacteria in the gut microbiome are responsible for so many important functions. Their influence is far-reaching as it relates to overall health. Research shows us that the more diverse that community of bacteria is, the more beneficial it is to systemic health. But what does diversity mean and how do we measure it? There are many calculations used when it comes to diversity of the microbiome, and they can sometimes give differing information. It’s important to understand what’s being measured in order to clinically correlate the result. In today’s episode, we discuss the industry standard Shannon Diversity Index as measured on Genova’s brand new Microbiomix profile. Today on The Lab Report: 3:15 Better Know a Biomarker: Shannon Diversity Index 6:00 Evenness and Richness 7:30 Alpha vs. beta diversity 10:05 Who’s Claude Shannon? 13:00 Get Outta Here! 15:50 Simpson vs. Shannon Index 17:40 The numerical score 19:45 Improving the diversity score Additional Resources: GI Effects with Microbiomix Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

The NutrEval Profile is Genova’s most comprehensive nutritional assessment providing a framework of core nutrients in the areas of antioxidants, B-vitamins, digestive supports, essential fatty acids, and minerals. This functional evaluation is aimed at assessing nutrient insufficiencies and biochemical individuality. In the Medical Affairs department, we are privileged to speak with clinicians every day to interpret test findings in clinical context, answer general questions about testing, and dive into the latest literature to expand our understanding too. On today’s episode, we address the top 5 most frequently asked questions about the NutrEval. Although we are focusing on the NutrEval, these questions and answers can also apply to our other nutritional testing as well. Today on The Lab Report: 3:40 Do I need to stop supplements to perform testing? If so, for how long? 7:30 How does urinary creatinine affect findings? 11:00 What do the neurotransmitter metabolites tell us about the brain? 15:00 How do I interpret a NutrEval report that is released in two parts? 17:25 If the direct RBC magnesium result is normal, how is there still a magnesium recommendation on the nutrient recommendation page? – Similarly, if my serum B12 level is normal, why are there recommendations for more on the NutrEval? Additional Resources: NutrEval Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

There are very few key opinion leaders that hold extensive certifications in functional and integrative medicine who not only lecture, mentor, and teach but also continue to practice full-time and harness decades of clinical expertise like Dr. Filomena Trindade. An internationally sought-after speaker, and mentor to hundreds of clinicians, Dr. Trindade continually scours literature for the latest research on hormonal and metabolic health. Her latest focus has been cardiovascular disease. On today’s episode, we dive into the latest insights regarding cardiovascular disease in women with Dr. Filomena Trindade. We discuss the interplay between women’s hormones, insulin resistance, and metabolic health. Today on The Lab Report: 4:20 Meet Dr. Filomena Trindade 6:40 State of the evidence regarding women’s health and cardiovascular disease 11:25 Atypical lipid patterns in hormone dysregulation 14:20 Discrepancies in pain patterns – men vs. women 16:30 Atherogenesis and inflammation in women 19:50 The role of SNPs and hormone regulation 22:45 Perimenopause and menopause mechanisms in heart disease 25:00 Metabolic health and the hormone symphony 30:00 Biomarkers, visceral adiposity, and insulin resistance 35:25 Radiologic scanning, body impedance measurement, and physical exam 38:00 Increasing muscle mass vs. decreasing carbohydrates 41:10 Mentorship for new clinicians 46:30 The Fireball Additional Resources: drtrindade.com Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Inflammation is your body’s way of protecting itself from infection, injury, or other insults. Chemical signaling molecules called ‘eicosanoids’ are responsible for creating pain, heat, swelling, and redness. Eicosanoids are made from fatty acids, or dietary fats. We’ve all heard of fish oil and omega-3s being important when it comes to lowering inflammation. But why? In today’s episode, we break down the inflammatory cascade, explain how fatty acids are involved, and we answer the question ‘What in the world is an eicosanoid!?’ Today on The Lab Report: 3:20 What are eicosanoids? 6:05 Fatty acids and the inflammatory cascade 9:10 Lipoxygenase (LOX) and cyclooxygenase (COX) 10:00 The COX eicosanoids – prostanoids and thromboxane 12:10 Leukotrienes, lipoxins, resolvins, and LOX 13:15 Aspirin, fish oil, and heart disease 16:30 Question of the Day How should we measure fatty acids? Additional Resources: NutrEval Essential & Metabolic Fatty Acids - Bloodspot The omega-3 index as a risk factor for coronary heart disease Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Dr. Dwayne Jackson has spent decades in medicine and physiology. He lectured and taught at some of the finest universities in the world. In addition to academia, Dr. Jackson has been a staple in the fitness industry - both as an athlete and trainer. He is recognized internationally for his award-winning research which has shaped our understanding of chronic stress and its impact on immunity, inflammation, and mental health. In today’s episode, Dr. Dwayne Jackson combines his vast knowledge of physiology with his long career in the fitness industry to help us cut through some of the noise related to nutrition, supplements, and mental-emotional stressors. Today on The Lab Report: 4:00 Meet Dr. Dwayne Jackson – his career in academia and his reason for leaving 8:25 Path from dialysis to kidney transplant 14:40 Benefits of creatine supplementation and concern around kidney disease 20:40 The most over-hyped supplements 22:10 Recovery, sustained efforts, and stress on the body 25:40 Beyond protein – micronutrients, antioxidants, and balanced diets for performance 31:45 Endurance athletes, cortisol, gut health, and burnout 34:45 Body dysmorphia in elite athletes 41:00 Beyond athletes - working with patients with chronic illness 45:40 Creating consistency and working with Dr. Jackson 50:00 The Fireball Additional Resources: Dr.DwayneJackson.com @drdnjackson Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Amber Shaw is a Mind & Body Transformation Expert and the Founder of The Wellness Revolution. She works with women over the age of 40 to empower them to rediscover their confidence and create a sustainable lifestyle. Amber’s approach fosters consistency, accountability, and kindness. Women can be quite hard on themselves rather than show self-love. Shifting hormones, the demands of family and career, and a very confusing diet landscape can all be difficult to navigate. This is where Amber Shaw chose to build her career. On today’s episode, Amber Shaw talks about helping women heal their relationship with food and themselves while empowering them to transform their lives, love their bodies, and create lasting results. Today on The Lab Report: 3:30 Meet Amber Shaw and hear her inspiring story 13:45 Raising children in a body-shame culture 17:10 Kindness, self-love, and shifting that mentality 21:00 Stop tying weight and metrics to self-esteem 23:40 Fostering consistency, not perfection 28:40 Avoiding diet camps, calories in – calories out, deprivation 33:00 Menopause, peri-menopause – old tricks no longer work 37:00 Work with Amber Shaw – sorry guys, women only 39:30 The Fireball Additional Resources: AmberShaw.com The Wellness Revolution Podcast Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Inflammatory bowel disease or IBD is an umbrella term to describe chronic inflammatory disorders of the GI tract – most commonly Crohn’s disease and ulcerative colitis. Medications, nutritional therapies, and lifestyle modifications are all used to control symptoms and keep patients in remission. However, sometimes surgical intervention is needed. Dr. Elizabeth Raskin is an award-winning colorectal surgeon and the Surgical Director of one of the leading IBD programs in the country – the Hoag Margolis Family IBD Program. This team-based, multidisciplinary approach to helping patients with IBD addresses the medical, nutritional, and psychosocial components to these diseases. Today we speak with Dr. Elizabeth Raskin, one of the leading colorectal surgeons in the country. We hear about her unique approach to IBD - combining nutrition, functional medicine, mental, spiritual, and emotional support for better patient outcomes. Today on The Lab Report: 3:30 Meet Dr. Raskin and hear about her dedication to healing the colon 9:30 Nutritional challenges with IBD patients 14:40 Pre-habilitation before surgery 17:05 Post-op advice for primary care clinicians 20:55 IBD prevalence 22:50 The microbiome and surgery – pre and post op support 30:20 Triggers of IBD 33:50 Personalized approach to Crohn’s disease 38:00 Endurance athletics and the gut 46:45 The Fireball Additional Resources: Hoag Margolis Family IBD Program Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Dr. Lauryn Lax is a Doctor of Occupational Therapy, Clinical Nutritionist, Functional Medicine Practitioner, Certified Personal Trainer, author, and journalist. With over 20 years of clinical and personal experience, she’s on a mission to help patients feel good - inside and out. But what sets Dr. Lauryn apart is her life-long journey of illness and healing. It’s a story of joy, pain, bravery, and survival. This journey has resulted in an empathic heart, a holistic philosophy, and tools that can transform lives. In today’s episode, Dr. Lauryn Lax shares her incredible story of personal healing to help heal others. We discuss the gut’s relationship to mental-emotional state, breaking free of strict food rules, and how to use German New Medicine to uncover true root causes. Today on The Lab Report: 4:50 Meet Dr. Lauryn Lax 6:00 The Story 21:30 Lessons learned – new insights 23:30 Food freedom and clean eating 28:30 Where to start? Nourish the gut 34:00 Mental-emotional work 39:00 The real root cause: German New Medicine 44:50 The Fireball Additional Resources: dr.lauryn.com Dr. Lauryn's books Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

The topic of intestinal parasites and their prevalence is hotly debated in functional medicine. Furthermore, the increasing trend of people performing a ‘parasite cleanse’ of the GI tract can be dangerous. Parasites are diagnosed in the stool using microscopy, direct exam, and PCR – but even then, not all parasites should be treated. Some can cause significant illness, yet others are not invasive, self-limiting, and considered nonpathogenic. In today's episode, we give a refresher course on gut parasites, discuss different ways to assess them, and introduce the topic of nonpathogenic parasites that don’t need to be treated. Today on The Lab Report: 3:50 Prevalence and transmission of parasites 6:45 What is a parasite? Are there nonpathogenic parasites? 8:10 3 main classes of parasites 10:20 Detecting parasites in the stool 13:10 Nonpathogenic parasites Chilomastix mesnili, Endolimax nana, Entamoeba coli, Entamoeba dispar, Entamoeba hartmanni, Entamoeba polecki, Iodamoeba buetschlii 16:50 Potentially pathogenic parasites 19:25 Question of the Day Why doesn’t Genova offer sensitivities for parasites on the GI Effects? Additional Resources: GI Effects Stool Profile Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Methane is often in the news as a greenhouse gas, but guess what? Your gut microbiome also makes it. Specific organisms called methanogens are responsible for the production of methane in the GI tract. High levels of methane can locally affect gut motility and contribute to constipation. In addition to constipation, methane affects gut immunity and has some interesting systemic implications. In today's episode, we talk about the effects of methane production in the GI tract, various ways to assess it, and what you can do to treat it when levels get too high. Today on The Lab Report: 2:45 Glory and Shade 5:20 Gas and the microbiome 6:30 Archaea vs. bacteria 8:30 Cows and methane 9:15 Methanogenesis in the GI tract and disease associations 12:15 Breath testing and IMO 14:40 Methane Dysbiosis on GI Effects 18:35 Whole-genome sequencing with Microbiomix 19:40 Treating high methane 22:45. Question of the Day What about low methane? Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Living with acne, or any chronic skin condition, can be incredibly distressing. Skin is the largest organ in our body and is forward-facing for the world to see. Conventional medicine offers creams, gels, and antibiotics. But in personalized medicine, we know that acne is multi-factorial and has several root causes. Lienna May is a board-certified clinical nutrition specialist who is dedicated to helping patients struggling with acne by developing personalized lifestyle and nutrition programs for patients to reclaim their health and clear their skin. In today’s episode, Lienna May discusses the root causes of acne and outlines her holistic approach for long-term relief. Today on The Lab Report: 3:35 Meet Lienna May and hear about her passion for treating acne 8:45 Gut health and acne 11:40 Stress, cortisol, and skin 15:50 Nutritional deficiencies and food triggers 21:20 Sugar, acne, and continuous glucose monitoring 24:30 Exercise, movement, and acne 28:00 Types of acne and triggers 30:35 The Fireball Additional Resources: Lucky Avocado Nutrition Acne Quick Solution Guide Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Lacey Dunn is a functional medicine dietitian and personal trainer who is passionate about helping women look and feel their best. Lacey is the founder of Uplift Fit Nutrition (an online platform for personalized support), host of the Uplift Fit Nutrition Podcast, and author of the book “The Women’s Guide to Hormonal Harmony – How to Rebalance Your Hormones, Master Your Metabolism, and Become the Boss of Your Own Body.” Many of her clients call her their “Hormone Fairy Godmother.” In today’s episode, Lacey Dunn gives a masterclass on the functional approach to balancing hormones and balancing your life. Today on The Lab Report: 3:30 Lacey Dunn discusses her journey to hormonal balance 8:55 Symptoms, clinical presentations, and root cause 11:30 Where to start? Adrenals, stress, and taking a breath 14:00 Testosterone in women 17:30 The role of diet in hormonal balance 21:10 Microbiome and HPA axis 23:20 Obstacles and behavior change 25:15 The Women’s Guide to Hormonal Harmony – for men? 27:25 The Fireball Additional Resources: Uplift Fit Nutrition The Women's Guide to Hormonal Harmony Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Dr. Mike T Nelson is an exercise physiologist, researcher, speaker, author, personal trainer, and coach. In the world of sports optimization, his approach to coaching world-class athletes is innovative and science-driven. Dr. Mike’s years of research and coaching experience, paired with an open mind to new ideas, have garnered his clients amazing results. A teacher at heart, he also offers several key training opportunities and certifications to help athletes, coaches, and healthcare professionals to fully understand the physiology that drives meaningful changes. In today’s episode, Dr. Mike T Nelson outlines the basics of physiologic flexibility and ways to train our metabolism to become more resilient and anti-fragile. Today on The Lab Report: 3:00 Mike T Nelson is back and so is the Flex Diet certification 7:00 Diet Wars and Keto 9:45 Physiologic flexibility and homeostatic regulators 14:00 Regulating respiration and pH 20:15 Controlling temperature, metabolism, and mental fortitude for resiliency 27:15 Advanced recovery methods and wearable devices 38:15 Volume vs. intensity 40:20 The Fireball Additional Resources: miketnelson.com Physiologic Flexibility Certification Course Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Here at Genova, we are incredibly proud of the high standards set by our laboratory director and the brilliant minds that work in the lab to keep things running smoothly. As clinicians, and consumers, many of us don’t give the inner workings of the lab a second thought. We take for granted that samples are sent, results are generated, and we can clinically act on those findings. Most of our profiles rely on several different laboratory methodologies to put the whole story together. One of those methods is called Chromatography – and clinicians don’t fully understand what that actually means. In today’s episode, we call on our friend Ashley Gibbon – one of the smartest minds in laboratory science – to help us understand what chromatography is and why it is so vital to Genova testing. Today on The Lab Report: · 7:10 Ashley Gibbon defines chromatography · 14:15 Organic acids and Separation science · 16:15 The instrument – columns, beads, mobile and stationary phases · 19:25 Detectors and mass spectrometry · 23:15 Liquid vs. Gas chromatography · 26:00 Maintaining the beads to preserve peaks · 28:05 Quadrupoles, Sensitivity and specificity of detectors, and quantification · 31:00 Area under the curve, inhibitors and interferents, coefficient of variance · 34:00 Question of the Day What is clinical vs. analytical sensitivity/specificity? Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guest See omnystudio.com/listener for privacy information.

The importance of B-vitamins can not be overstated. They are used as cofactors in just about every biochemical pathway in the body. Overt B-vitamin deficiencies are not common, though many diet and lifestyle factors can influence levels and lead to insufficiencies. Symptoms of B-vitamin deficiencies are widely variable and not often recognized. Many people choose to take B-vitamin supplements. But why? Should we all be taking a B-complex vitamin? Is it possible to take too much? On today’s show, we do a high-level overview of B-vitamins. We talk about the importance of each B-vitamin in the body, symptoms of insufficiency, and why you might need to supplement. Today on The Lab Report: 3:55 What is a vitamin? 5:15 Naming convention of B-vitamins 7:55 Biochemical cofactors 9:35 Thiamine (Vitamin B-1) 11:00 Riboflavin (Vitamin B-2) 11:55 Niacin (Vitamin B-3) and Pellagra 13:55 Pantothenic Acid (Vitamin B-5) 14:50 Pyridoxine (Vitamin B-6) 17:15 Biotin (Vitamin B-7) 20:10 Folate (Vitamin B-9) 21:35 Cobalamin (Vitamin B-12) 24:15 Supplementation Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.