The Lab Report

The metabolic health crisis continues to grow. In the midst of the COVID-19 pandemic, this became even more obvious as it relates to patients’ poor outcomes and lack of resiliency. Dr. Taylor Sittler is the Head of Research at Levels Health, an industry leader in continuous glucose monitoring. His work at Levels aims to help people take control of their diet and lifestyle to improve metabolic resiliency and optimize their health. Today, we talk to Taylor about the origins of this mounting crisis of metabolic dysfunction, his thoughts on the best ways to measure it, and what we can do to improve our resiliency.  Today on The Lab Report: 3:15 Taylor Sittler and his path to Levels 7:30 Origins and scope of the metabolic health crisis 15:45 Cortisol and COVID 17:30 What is metabolic resiliency? 21:45 Measuring metabolism 25:15 Fat vs. Muscle-centric theories of metabolic dysfunction 28:15 What can we do to improve our resiliency? 33:30 CGM and how Levels is optimizing health 41:45 The Fireball Additional Resources: Levels Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Dr. Sheila Dean is one of the nation’s premier integrative nutritionists. She is a co-founder of the Integrative and Functional Nutrition Academy and has practiced functional medicine for two decades. Her insight has not only changed the lives of many patients, but her teaching and mentoring has inspired and empowered a new generation of nutrition specialists and health professionals. In today’s episode, we dive into one of Dr. Dean’s keen interests – metabolic detoxification. We discuss the physiologic process of detoxifying xenobiotics and hormones and why nutrition, genomics, and the microbiome are vital. Today on The Lab Report: 3:00 Meet Dr. Sheila Dean and hear about her path to functional medicine 9:15 Toxins, Detox, and Biotransformation 13:15 Phase I and Phase II pathways 16:35 Nutrition, genetic SNPs, and detoxifying hormones 24:45 Clinical strategies for optimizing key detox pathways 31:00 All about IFNA 33:40 The Fireball Additional Resources: Integrative and Functional Nutrition Academy DetoxiGenomics Essential Estrogens Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Your smartphone weather app likely includes insight into the “Air Quality Index”. But what does it mean and why should you care? We don’t often stop to take into consideration the quality of the air we breathe. Environmental toxins are everywhere – food, water, soil, and yes, air. Not only can toxins in the air directly affect your lungs, but there are also long-term systemic health effects that may be less obvious. In today’s episode, we talk about indoor and outdoor ‘air quality,' the connection to chronic disease, and ways to mitigate potential damage. Today on The Lab Report: 4:00 Outdoor air and the Air Quality Index 8:00 Indoor pollutants 9:20 Off-gassing and ventilation 14:30 Health effects of air toxins 19:00 Air filters and purifiers 23:30 House plants to the rescue! Additional Resources: Environmental Health Perspectives Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Burning extra calories doesn’t have to mean hardcore exercise. Your body uses energy all day long just breathing, digesting food, toe-tapping, and standing. This basic movement is called ‘non-exercise activity thermogenesis’ and at the end of the day can add up to tremendous energy expenditure. But just how much? Can we maximize it for long-term weight management? Are we eating enough calories in the day to compensate?   In today’s episode, we discuss this NEAT concept – non-exercise activity thermogenesis. We talk about metabolic energy, movement, and caloric balance. Today on The Lab Report: 3:30 Energy, metabolism, and basal metabolic rate 5:30 How many calories does it take to keep the lights on? 7:30 Non-exercise activity thermogenesis (NEAT) vs. exercise 16:35 A NEAT game 20:05 The thermic effect of food 21:55 Question of the Day Can you fidget your way into a calorie deficit for weight loss? Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

We can all agree that chocolate is delicious. Is it possible that it’s also healthy for us? How many of us stop to consider that it comes from a tree? What is it about that tree and its seeds that can benefit our health? With all that sugar, is chocolate good or bad for us?   Today we discuss where chocolate comes from, the difference between white/dark/milk chocolate, and some interesting health benefits.  Today on The Lab Report: 3:00 Why are we talking about chocolate? 4:30 From tree to candy bar – a chocolate flow chart 8:00 History of the ‘Food of the Gods’ 10:00 White chocolate and the bitter butter battle 13:30 Health benefits of dark chocolate 15:00 Kitchen Cook-cophany! Additional Resources: Keto Chocolate Chip Cookies Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Dr. Dominic D’Agostino is a well-known leading researcher who studies nutritional strategies and metabolic-based therapies in neurological disorders, seizures, cancer, and metabolic wellness. He also happens to be a preeminent voice and proponent of the ketogenic diet. Ketosis is your body’s ability to burn fat for fuel when carbohydrates are not readily available – producing ketones. No longer thought of as a fad diet, it is actually a metabolic state that many adopt as a lifestyle given the emerging health benefits it confers. The metabolic effects of ketosis are vast and new insights are evolving rapidly. In today’s episode, we dive deep into biochemistry and metabolism with Dr. D’Agostino. He explains the latest research advancements in ketosis, differences between endogenous and exogenous ketones, and how continuous glucose monitoring factors into ketosis and metabolic health measures. Today on The Lab Report: 4:00 Welcome back, Dr. D’Agostino – why he chooses to study ketosis? 6:50 Surprising new clinical applications of ketogenic diets 12:40 Alzheimer’s disease, type 3 Diabetes, and ketones 17:00 Exogenous ketone esters/salts vs. endogenous ketones and metabolic effects 26:30 Is there a role for the ketogenic diet in ADD/ADHD? 29:15 Continuous glucose monitoring and ketosis 34:35 Glucose/ketone variation and the calculated index 43:00 Metabolic Health Summit 46:40 The Fireball Additional Resources: KetoNutrition Metabolic Health Summit Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Dr. Jaclyn Chasse-Smeaton is an international teacher and lecturer who is considered a preeminent expert in integrative and functional medicine approaches to infertility. As a naturopathic physician, she has helped hundreds and hundreds of couples conceive- even in cases that seemed hopeless - through her private practice and mentorship programs. In today’s episode, Dr. Smeaton outlines her approach using root cause medicine and uncovers factors that are often overlooked when it comes to infertility. We discuss diet, nutrition, the gastrointestinal microbiome, exercise, and stress management – and why they matter when it comes to fertility. Today on The Lab Report: 3:30 Meet Dr. Jaclyn Smeaton and hear why she focuses on women’s health 7:15 Lack of options for women hormone imbalances and infertility gender bias 13:30 The microbiome and fertility 15:30 Nutrition optimization in preconception and maintaining a pregnancy 17:15 Using functional medicine testing in fertility 19:10 Debunking exercise myths in pregnancy 20:45 HPA axis balance in motherhood and fertility 22:30 Emerson Ecologics and Wellevate 25:10 The Fireball Additional Resources: Hello Fertility Emerson Ecologics Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.    See omnystudio.com/listener for privacy information.

Dr. Pam Smith is one of the most revered teachers and mentors in integrative medicine. After years of practicing emergency medicine, then decades as an Anti-Aging/Metabolic Medicine specialist, Dr. Smith is a go-to resource for many new clinicians. She’s written several books on a variety of precision medicine topics though is widely known for her work in hormone balance and bioidentical hormone replacement therapy (BHRT). Today, we dive into hormone balance with Dr. Pam Smith. She offers her insight into various types of BHRT, testing options and pitfalls, and we preview her upcoming book “What You Must Know About Women’s Hormones (2nd edition)”.   Today on The Lab Report: 5:55 Meet Dr. Pamela Smith and hear her thoughts on the evolution of precision medicine 9:55 Hormone balance, systemic effects, and when to start BHRT 12:35 Bioidentical vs. synthetic hormones 13:40 Compounding pharmacies, bases, and delivery systems 16:30 When to use various hormone testing types 19:55 Detoxification and methylation 21:45 Spurious testing results – Where to start? Timing of dosage? Exogenous exposure? 25:15 What You Must Know About Women’s Hormones & the soon to be released 2nd edition 27:00 The Fireball Additional Resources: Center for Precision Medicine One Day Hormone Check Complete Hormones Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Inflammation is your body’s way of protecting itself from infection, injury, or other insults. Chemical signaling molecules called ‘eicosanoids’ are responsible for creating pain, heat, swelling, and redness. Eicosanoids are made from fatty acids, or dietary fats. We’ve all heard of fish oil and omega-3s being important when it comes to lowering inflammation. But why? In today’s episode, we break down the inflammatory cascade, explain how fatty acids are involved, and we answer the question ‘What in the world is an eicosanoid!?’ Today on The Lab Report: 3:20 What are eicosanoids? 6:05 Fatty acids and the inflammatory cascade 9:10 Lipoxygenase (LOX) and cyclooxygenase (COX) 10:00 The COX eicosanoids – prostanoids and thromboxane  12:10 Leukotrienes, lipoxins, resolvins, and LOX 13:15 Aspirin, fish oil, and heart disease 16:30 Question of the Day How should we measure fatty acids?   Additional Resources: NutrEval Essential & Metabolic Fatty Acids - Bloodspot The omega-3 index as a risk factor for coronary heart disease    Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Dr. Christian Jenski is a conventionally trained emergency room physician who has made the huge leap to functional and precision medicine. Many of you will remember him from a prior episode where we discussed the clinical application of functional medicine testing and he offered his real-world examples and testimonials showcasing the power of root-cause medicine. Due to overwhelming feedback from listeners, both clinicians and patients alike, Dr. Jenski is back! Today we focus on the core principle that ‘all disease begins in the gut.’ Dr. Jenski discusses the way GI abnormalities can underlie many, if not all, chronic health conditions, what to look for on a stool test, and why you should care.    Today on The Lab Report: 3:40 Christian Jenski is back! 5:30 ‘IBS’ stool testing patterns 8:05 The gut and systemic disease 13:25 Wow! moments – when in doubt, heal the gut! 14:45 Treating dysbiosis – supplements, diet, and more 17:40 Hormonal imbalances and the GI tract 21:50 Elimination diets and food sensitivities/allergies 29:00 The Fireball Additional Resources: Richmond Integrative & Functional Medicine GI Effects Stool Profile   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.    See omnystudio.com/listener for privacy information.

The thyroid gland is responsible for regulating metabolism and is sometimes referred to as the ‘thermostat’ of our bodies. Even minor abnormalities in thyroid function can have far-reaching effects on every organ system. Thyroid diseases are prevalent worldwide and thyroid hormone replacement therapy is common. But many don’t realize that there are basic dietary nutrients that can have a huge impact and help optimize thyroid function. In today’s episode, we recap thyroid physiology and discuss how nutrition underpins thyroid hormone synthesis and metabolism. Today on The Lab Report: 4:00 Recap of basic thyroid gland physiology 7:45 Iodine and types of salt 10:45 Selenium, selenoproteins, and orbital rings 13:15 Everyone’s favorite cofactor - zinc 14:45 Iron and heme-dependent enzymes 16:10 Protein and amino acids 17:30 Question of the Day: Why does the NutrEval measure these nutrients in different matrices? Additional Resources: Comprehensive Thyroid Assessment NutrEval Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Any clinician who enters the medical profession understands that a large part of the training is learning the lingo and essentially a new language. Even those who have been in practice for quite some time know that new fields of study emerge, and new terms can be borne out of that. Sometimes the medical jargon can get confusing even though what is being discussed is not new. In today’s episode, we discuss some of the latest terms and how/why their use in clinical practice evolves. We also try to clarify a few concepts that many of us confuse and misuse. Today on The Lab Report: 3:25 Medical lingo and jargon 4:00 Omics…… and ‘ooooomm’ 6:00 Proteomics, genomics, transcriptomics 7:15 Metabolomics and making sense of patterns 11:15 The Jargonomics Game British vs. American medical terms 14:30 Causation and correlation 18:20 Question of the Day What’s the difference between sensitivity and specificity?   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

We tend to lean on traditions during the holiday season. As they are handed down through the generations, their origins are often forgotten. Not only do traditions offer comfort and help to unify us, but many also have important health benefits. Today we have some fun with the origins of several holiday traditions and weave in their clinical significance. Make sure to stay tuned for a special Genova version of ‘Twas the Night Before Christmas!   Today on The Lab Report: 2:50 Mistletoe – antioxidants and smoochie smoochie 5:00 Pine, conifers, and evil spirits 7:35 Peppermint candy canes and carminatives 10:35 Checking in with the UK – Oliver’s fear of figgy pudding 14:40 Gingerbread houses made from the super-herb 17:40 Gift-giving and ‘Off the Cuff’ with the Medical Affairs team 24:55 ‘Twas the Night Before Christmas ??????? Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Cellular respiration is the process of converting our food into energy to fuel the body. It involves many biochemical reactions to create a molecule called adenosine triphosphate (ATP) - our main energy source. When it comes to ATP production, many of us think about the Krebs Cycle not realizing it is only part of the story. The Electron Transport Chain bears the brunt of the work to keep our cells alive and our bodies functioning optimally. Although biochemistry can seem challenging, in today’s episode we break it down into simplistic terms and explain why you should care about it. Listen as we discuss the importance of the electron transport chain. Today on The Lab Report: 2:15 Basic overview of cellular respiration and ATP 4:50 Breaking it down 7:45 The Krebs Cycle and NADH/FADH2 8:30 Electron Transport Chain and the bucket brigade 10:55 ATP Synthase is cool 13:20 High-level recap 14:15 Oxidative stress and CoQ10 17:30 Question of the Day: Who is Krebs? Additional Resources: ATP Synthase in action NutrEval Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

The pancreas is an organ that functions as a gland in the endocrine system by secreting hormones into circulation that help with regulating glucose. However, it also plays an integral role as part of the digestive tract by secreting enzymes to help digest our food. When the digestive functions of the pancreas start to decline what results is Exocrine Pancreatic Insufficiency or EPI. In addition to physical symptoms and digestive complaints, EPI has important clinical implications. In today’s episode, we discuss exocrine pancreatic insufficiency – causes, clinical associations, diagnosis, and treatment. Today on The Lab Report:   3:00 The role of the pancreas 5:15 Exocrine vs. endocrine glands 8:20 Exocrine pancreatic insufficiency 10:15 Logical Speculation: SIBO and EPI 13:35 Causes of EPI and signs/symptoms 17:05 Treatment considerations 18:20 Question of the Day? Does Genova test for EPI? Additional Resources: GI Effects Comprehensive Stool Profile Stool Testing Support Guide Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Thanksgiving is a time to be mindful and reflect on our many blessings. During the holiday, many of us enjoy dinner with family and friends without stopping to consider the nutritional aspects of traditional dishes. Today, we discuss the important biochemical and nutritional benefits of Thanksgiving dinner items. We also talk about dealing with the stress of the holidays and the many reasons we are grateful. Today on The Lab Report: 3:30 Turkey and tryptophan – is it a thing? 5:15 Cranberry sauce apologetics 7:45 Potatoes! - and the microbiome 10:35 Green bean casserole, (fake) mushrooms, and onions 13:15 Hollandaise sauce? Gravy? Stuffing? Ummm…moving on 14:10 Pumpkin is a fruit 15:20 Moderation and modifying your dinner 16:15 Movement and mindfulness 19:20 Gratitude and community – Patti & Michael give thanks Additional Resources: Michael's Famous Green Bean Casserole? Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

The one-size-fits-all approach doesn’t work when it comes to diet and nutrition. What works for some may not be right for all. Diet movements like intermittent fasting, the ketogenic diet, and veganism are becoming increasingly popular and widely adopted. Laura Ligos is a registered dietitian and nutritionist who created a platform called “The Sassy Dietitian” which gives people a safe place to learn and ask questions about nutrition. She works to debunk health myths and help people understand the importance of dietary choices for optimal wellness. In today’s episode, Laura gives her thoughts on changing the diet mindset and discusses some of the pitfalls and concerns related to popular diet trends. Today on The Lab Report: 3:55 Meet Laura Ligos – the Sassy Dietitian 8:15 Changing the ‘diet’ mindset 10:50 Does everyone need a supplement? 13:40 Pitfalls of the ketogenic diet 16:00 The Game Changers documentary and vegan diets 22:50 Intermittent fasting and restricted eating 27:10 Intuitive eating 30:00 The Fireball Additional Resources: The Sassy Dietitian The Busy Person's Meal Planner Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Wearable devices have become an integral part of sports performance in elite athletes. However, many non-athletes have adopted them as well to optimize sleep, stress, and overall health. WHOOP has been the industry leader in the marketplace while continuing to innovate and promote healthy lifestyle and behavior change. Kristen Holmes is the Vice President of Performance Science at WHOOP. Not only is she an accomplished athlete herself, she’s also a PhD candidate pursuing a doctorate in psychology. Coupling her athletic background with her keen interest in psychology and physiology, Kristen works with WHOOP to offer tangible performance and health data to help anyone transform their lives with positive behavior change, fitness improvements, and injury reduction. In today’s episode, we talk to Kristen about her definition of optimal performance and how WHOOP can help you achieve it. Today on The Lab Report: 3:25 Meet Kristen Holmes – from athlete, to coach, to VP of Performance Science 6:45 What is WHOOP and why is it different? 7:55 Heart rate variability for recovery and resilience 11:15 The New WHOOP 4.0 and WHOOP Body 15:00 The impact of sleep deficits – Can Michael sleep ‘harder’? 21:15 Kristen’s definition of Optimal Performance and how can WHOOP help? 30:30 Downside of wearable devices 33:45 The Fireball Additional Resources: WHOOP Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Today’s society has its challenges regarding stress and emotional well-being. We can all agree that mindfulness, community, and better mental health options are needed. Although meditation can be helpful, it can also be intimidating for beginners. Breathwork is a great, simple alternative. Robbie Bent is the co-founder and CEO of Othership – a physical and digital wellness company with structured programs to reduce stress, improve sleep, boost energy, and improve mood using breathwork techniques. In this episode, Robbie Bent outlines the difference between mediation and breathwork, the health benefits of structured breathing techniques, and even leads us in a breathwork session. Today on The Lab Report: 3:30 Meet Robbie Bent and hear about his journey to breathwork 10:15 Breathwork and parasympathetic/sympathetic balance 14:20 Mouth vs. nasal breathing and mouth taping 21:10 Differences between mediation and breathwork 24:55 The community at Othership and revolutionizing mental health 31:55 Ice baths, sauna, and emotional resilience 37:00 Robbie leads us in a breathwork session!!!!   (*Don’t do this while driving) 49:30 Emotional connection and shifting emotional states 53:00 Connect with Robbie and work with Othership 53:45 The Fireball   Additional Resources: Othership Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.      See omnystudio.com/listener for privacy information.

As a practicing emergency room physician, Dr. Tom McCoy has seen the downstream effects of unhealthy diet and lifestyle choices. While continuing to practice ER medicine, he obtained additional certifications in nutrition and exercise training and is a CrossFit MDL1 medical practitioner. He uses all of this experience and knowledge as part of The Vital Human Project – a coaching program that blends fitness, nutrition, education, and more to help people realize their full human potential. On today’s episode, Dr. Tom discusses behavioral change, sleep, nutrition, and exercise - and the impact they have on becoming a Vital Human. Today on The Lab Report:  3:45 McCoy on the short-comings of conventional medicine 7:05 The Vital Human Project 10:30 CrossFit and benefits of HIIT 12:40 The intimidation factor 15:15 Coaching clients for behavior change 17:55 Hunting, respect, and sourcing quality meat 20:55 Impactful lifestyle factors for health 23:00 The Fireball Additional Resources: The Vital Human Project Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

“Gluten” has become a buzzword in the diet industry and vilified in the court of public opinion – perhaps rightfully so. People are continually looking for gluten-free labels in the grocery store and on restaurant menus trying to be healthier. But why? What is gluten anyway? How does it affect our health? Should no one ever eat gluten again?  In today’s episode, we break down what gluten actually is, what foods contain it, and what happens in the GI tract when we eat it. Today on The Lab Report: 2:45 What is gluten and why can't we digest it?  7:35 The effects of food manufacturing 9:15 Name that bread! 12:30 Celiac disease vs. gluten sensitivity 17:15 Foods that contain gluten 19:45 Question of the Day What can you eat on a gluten-free diet? 21:25 Beware of cross-contamination Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Small intestinal bacterial overgrowth (SIBO) is a common underlying cause of irritable bowel syndrome (IBS).  Bloating, constipation, diarrhea, excessive gas, or nausea are all hallmark SIBO symptoms. When it comes to diagnosis, the gold standard is endoscopic small bowel aspiration. This method is invasive, inconvenient, and not without risk. Breath testing and stool testing are now more commonly used. Today we dive into some specific patterns seen on stool testing that may point toward a SIBO diagnosis in symptomatic patients.   Today on The Lab Report: 2:50 IBS and bacteria in the small intestine 6:15 Symptoms of SIBO 7:35 Stool testing for IBS 9:05 Commensal abundance 10:00 Digestion and absorption markers 12:30 What do we think we know? Pancreatic elastase 1 and SIBO 16:35 Gut metabolites 17:50 Methanobrevibacter smithii and methane dysbiosis 19:50 Bacterial culture 20:50 Question of the Day How does methane slow transit time? Additional Resources: GI Effects Comprehensive Stool Profile   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Throughout the pandemic many clinicians and patients have learned to adapt and change expectations in their daily lives. Alongside all of those changes, the urgency for optimizing health became apparent. Functional and personalized medicine offers the greatest opportunity to advance how medicine is practiced. As a prominent health economist, James Maskell has been at the forefront of this movement for many years and championing its expansion to make true healthcare available for everyone. Through his many platforms including books, podcasts, international speaking events, and online practice implementation tools, James continues to further the conversation. In today’s podcast, we catch up with James and re-examine what’s worked throughout the past year and half as functional medicine has evolved as a community. We also discuss his latest venture HealCommunity to support patients and clinicians in behavior change adherence. Today on The Lab Report:   2:15    Introducing THE James Maskell   4:20    The Power of Community Healthcare   8:50    HealCommunity – Overcoming Obstacles To Community Medicine   17:20  Advantages of Groups – Reinforcement, Support, and Accountability   23:10  Monitoring Outcomes of Community Functional Medicine   25:55   Unforeseen Positives of Telemedicine   31:30   Return to LIVE Functional Forums   40:30   The Fireball  Additional Resources: Evolution of Medicine HealCommunity https://thecommunitycure.com/audiobook   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Elite athletes require physical and mental discipline to optimize their performance. However, adding an understanding of biochemistry and physiology can be a game-changer. Dan Garner specializes in fusing the science of health with the art of coaching for world-class results. Through his company Team Garner Inc., Dan offers high-level personalized training and nutritional coaching for a host of award-winning professional athletes and Hollywood actors. He is a functional medicine clinician, nutrition specialist, strength coach, trainer, lab analyst, best-selling author, and host of The Garner Report podcast.   In today’s episode, Dan Garner debunks some myths and gives some tips regarding supplements, rest and recovery, and diets. Dan’s practical advice can be scaled between elite athletes and anyone wanting to optimize health.   Today on the Lab Report:   4:00 Meet Dan Garner and hear his journey to Team Garner, Inc.   7:45 The myth of adrenal fatigue and interpreting cortisol levels  17:25 Developing a healthy relationship to food and diets  23:00 The psychology of prioritizing health   25:55 ‘Over-rated’ vs. ‘must-have’ supplements  36:40 Rest and recovery for athletic performance   40:10 Wearable devices   42:00 Applying lessons from elite athletes to the general population  46:30 The Fireball     Additional Resources:   CoachGarner.com   Subscribe, Rate, & Review The Lab Report  Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.  Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].   And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.   Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.      See omnystudio.com/listener for privacy information.

When assessing risk for cardiovascular disease, most clinicians focus on the concentration of low-density lipoproteins (LDL) also known as ‘bad’ cholesterol, and high-density lipoproteins (HDL) or ‘good’ cholesterol. Though this information is helpful, it’s only part of the picture when it comes to risk. Apolipoproteins are surface proteins found on all cholesterol molecules. They not only contribute to cholesterol structure, but also help to regulate enzymes responsible for lipid metabolism, assist in reverse cholesterol transport, and direct the distribution of fuel throughout the body. In today’s episode, we discuss apolipoproteins, their function, and why measuring them can be a game-changer when it comes to cardiovascular risk assessment. Today on The Lab Report: 3:45 What is an Apolipoprotein? 6:40 Particle number and particle size 9:00 Apolipoprotein A-1 and B 11:45 Better Know a Biomarker: Apolipoprotein B/A-1 Ratio 15:30 Lipoprotein (a) - Lp(a) 17:05 Question of the Day? What medications/supplements influence the Cardio Check? Additional Resources: Cardio Check   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.    See omnystudio.com/listener for privacy information.

Many clinicians and patients keep a close eye on cholesterol levels and standard lipid measurements as a way to stratify cardiovascular disease risk. What if there’s more to the story? Genova Diagnostics recently launched a brand-new profile called “Cardio Check.” This profile not only measures conventional lipid levels but also includes cardiometabolic biomarkers and lipid ratios which are being touted in the literature as even more clinically important than lipid levels alone. In today’s episode, we discuss a few of the lipid ratios included on the Cardio Check and explain why merely targeting LDL (aka the ‘bad cholesterol’) might be missing the mark for cardiovascular health. Today on The Lab Report: 2:25 THE CARDIO CHECK IS HERE! 5:00 We need cholesterol 6:50 ‘The Lipid Hypothesis’ 9:45 Low-density lipoprotein (LDL) and High-density lipoprotein (HDL) 12:00 Total Cholesterol/HDL Ratio 13:50 Triglycerides 15:25 Logical Speculation 17:25 Triglyceride/HDL Ratio 19:05 Question of the Day What are the diagnostic criteria for Metabolic Syndrome? Additional Resources: Cardio Check Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn.Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Dr. Nick Nwabueze, aka The Fittest Doc, ‘walks the walk’ when it comes to promoting a healthy lifestyle and teaching patients the importance of diet, exercise, and sleep. As a family medicine physician, he practices online with SteadyMD – a national telemedicine healthcare provider. Dr. Nick has a passion for developing real relationships with his patients to foster lasting changes. On today’s episode, we talk to Dr. Nick about all things health and wellness and discuss how virtual medicine plays an important role in today’s changing healthcare landscape. Today on The Lab Report: 3:25 Meet Dr. Nick and hear about his path to medicine 11:00 The importance of sleep! 15:00 Motivating patients to move 19:35 Nutrition for fat loss 23:20 Nick’s personal dietary choices 26:35 Pros and cons of telemedicine 34:35 Work with Dr. Nick 36:30 The Fireball Additional Resources: SteadyMD/Dr.Nick @thefittestdoc Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Pregnancy and childbirth are joyous and miraculous. However, they are also the most physically and emotionally challenging experiences a woman can endure. Dr. Lindsey Mathews created a movement called BIRTHFIT to offer a supportive community for women in motherhood transition and all cycles of life. Strength conditioning, nutritional guidance, emotional support, and educational resources are what make the BIRTHFIT community so popular. In today’s episode, we meet Dr. Lindsey Mathews and hear about her BIRTHFIT mission. She explains the birthing dream team approach and dispels some myths and misconceptions around pregnancy and postnatal care.  Today on The Lab Report: 4:30 Meet Dr. Lindsey Mathews and hear about her path to chiropractic medicine 7:50 Where did the idea of BIRTHFIT come from? 14:10 It takes a village 19:15 The mountain analogy 21:00 Myths regarding exercise and pregnancy 27:35 Posture and breathwork 34:15 Vaginal birth vs C-section: postnatal care 36:00 Work with BIRTHFIT 36:55 The Fireball Additional Resources: BIRTHFIT Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Did you know that there is a connection between the brain and the GI tract? This gut-brain axis communicates information in both directions. The commensal bacteria in our gut and their metabolites can directly affect our memory and mood, while our brain can alter bacterial patterns and GI function. Today we discuss some of the mechanisms by which this axis sends and receives those signals. We also talk about the importance of addressing both when optimizing health. Today on The Lab Report: 2:30 New Game Alert!  Vegetablization of names 4:05 Question of the Day/Fireball: Since the gut-brain axis is bidirectional, where do you start when it comes to treatment? 6:45 What is the gut-brain axis? 8:10 Communication mechanisms from the GI tract to the brain 13:20 How the brain affects the gut 16:50 Where do you start when it comes to treatment? 18:20 Psychobiotics 20:10 Testing   Additional Resources: GI Effects Comprehensive Stool Profile Adrenocortex Stress Profile  Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

In today’s society, many of us focus on losing fat to achieve and maintain adequate health. But the paradigm is slowly shifting toward the importance of gaining muscle. The metabolic and systemic effects of skeletal muscle are astounding. Dr. Gabrielle Lyon is a functional medicine physician who has pioneered a specialty in “Muscle-centric Medicine”. Years of research and study on the topic have shaped her unique approach to functional medicine and patient care. In this episode you’ll meet Dr. Gabrielle Lyon and learn about the metabolic influences of building muscle, how it contributes to longevity, and the importance of dietary protein.   Today on The Lab Report: 3:00 Meet Dr. Gabrielle Lyon and hear how her mentor has shaped her career 5:35 Metabolic and anti-inflammatory effects of muscle 9:45 Sarcopenia, insulin resistance, and obesity 11:10 Muscle mass and longevity 14:40 How much dietary protein do we need? 17:00 Animal vs. plant protein and supporting vegan/vegetarian patients 22:20 Red meat, flawed cancer studies, and mTOR 28:00 Lyon’s work with elite military operators 30:45 The Fireball   Additional Resources: Gabrielle Lyon's website Task Force Dagger Lyon's YouTube Channel   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Most of the meat we consume is from the skeletal muscle of animals, which provides a great source of protein in our diet. However, the organs of animals are incredibly nutrient-dense and often overlooked. They are great sources of essential fats, minerals, and vitamins. The common misconception is that organ meat is not palatable. Of course, this depends on which meats and how they are prepared. In today’s episode, we discuss the important nutrients you might be missing out on if you don’t eat “Offal”. Today on The Lab Report: 2:05 What is “Offal” eating? 4:25 Skeletal muscle vs. organ meat 7:35 Offal nutrients 10:45 Cautions when eating offal 13:20 Kitchen Cook-cophony! Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

The endothelium is a single layer of cells lining the inside of our blood vessels – and other internal organs. Not only is it responsible for signaling the contraction and dilation of vessels, but it controls clotting, inflammation, oxidative stress, and more! When this system breaks down, its effects are wide-reaching. Endothelial dysfunction is often the root cause of subsequent cardiovascular disease, strokes, and many chronic conditions. Because it can sometimes be reversible, understanding what causes it, how to treat it, and what you can do to prevent it becomes vital. In today’s episode, we discuss the physiologic role of the endothelium, how it relates to atherosclerosis, and practical strategies to promote cardiovascular health. Today on The Lab Report: 2:55 Defining Terms – What is the Endothelium? 7:10 Oxidative stress, inflammation, and drivers of endothelial dysfunction 11:00 How do we get to atherosclerosis? 14:20 Indirect causes of endothelial dysfunction 15:50 Direct causes and sheering forces 16:45 Sedentary lifestyle and other triggers 18:00 Movement, omega-3 fatty acids, herbal and prescriptive medications Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.    See omnystudio.com/listener for privacy information.

Functional medicine has come a long way from being just an “alternative” form of therapy. In recent years, we’ve seen more and more practitioners foregoing what they were taught in medical school to learn how functional medicine works and why many seek it over conventional medicine. What’s in store for the industry in the future? James Maskell joins us to share his predictions. James is a health economist, serial healthcare founder, and the owner of Evolution of Medicine, a company that helps functional medicine practitioners to start their own virtual practices. He is recognized as a healthcare disruptor, championing innovative ideas that promote prevention and reversal over traditional cures. James is also the host of the Evolution of Medicine podcast, a show featuring experts in the healthcare field that are driving the evolution of modern medicine. James joins us today to discuss the future of functional medicine. He shares his journey and the events that led him to be part of the functional medicine industry. He describes his clinic management experience, discusses the virtual conferences he hosts, and explains why now is the right time for virtual practitioners to thrive. James also shares why the primary care we receive will need to eventually change. The future of medicine is communities of people helping each other to get healthy.” - James Maskell This week on The Lab Report Podcast: Where his passion for disrupting traditional medicine came from. How he became part of the functional medicine industry. His experience in seminar speaking and clinic management. How he's managing to conduct multiple functional forums all over the world. What the future of medicine looks like. Virtual practices and how they're thriving during the pandemic. Applying lifestyle changes to chronic diseases over drugs. Why traditional doctors have to unlearn so much to become an expert in functional medicine. The kind of primary care we have in the United States.   Connect with James Maskell Evolution of Medicine Podcast Facebook Instagram   Subscribe, Rate & Review The Lab Report Thanks for tuning into this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts, Michael Chapman and Patti Devers. If you enjoyed this episode, please head over to Apple Podcasts to subscribe to the show and give us a rating and review. Don’t forget to visit our website, like us on Facebook, and follow us on Twitter, Instagram and LinkedIn. Email Patti and Michael with your most pressing questions on functional medicine. And be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.   Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions of Michael Chapman and Patti Devers and their guests. For medical advice, diagnosis, and/or treatment, please consult a medical professional.See omnystudio.com/listener for privacy information.

Gluten is a storage protein found in many foods, though mainly wheat, barley, and rye. It is a binder that helps food hold its shape. The human body is incapable of digesting and breaking gluten down. This can cause a host of immune reactions and lead to many chronic health conditions. Unfortunately, the prevalence of Celiac disease, wheat allergies, and non-Celiac gluten sensitivity is on the rise. Dr. Tom O’Bryan is one of the leading experts in functional medicine as it relates to gluten and autoimmunity. His work on wheat-related disorders, environmental toxicity, and autoimmunity is internationally recognized. In today’s episode, we discuss the devastating impact of gluten, environmental toxins, and autoimmune disease with the expert on these topics, Dr. Tom O’Bryan. Today on The Lab Report: 3:00 Meet Dr. O’Bryan and hear how aikido shaped his career path 8:50 Immunity vs. autoimmunity and intestinal permeability 21:50 Environmental toxicity and autoimmunity 31:45 Should everyone be gluten-free? 33:10 A balanced microbiome in addition to a gluten-free diet 40:25 Celiac disease, wheat allergy, and non-Celiac gluten sensitivity 46:10 The Gluten Summit 50:50 The Fireball Additional Resources: theDr.com The Gluten Summit The Autoimmune Fix Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

CrossFit is more than high-intensity interval training. It’s a community. C.J. Martin is an athletic coach, and a lawyer, who created Invictus Fitness as a community model to foster emotional support, education, and encouragement. His passion and singular focus have propelled his athletic teams to perennial success at the CrossFit Games and worldwide acclaim. C.J. also helped found a non-profit organization called ‘Kids Helping Kids’ which has raised millions of dollars for neo-natal and pediatric hospital units across the Northwest. Today, we hear C.J. Martin discuss the power of community and his passion for coaching people to become their best selves. Today on The Lab Report: 2:45 J. Martin on his journey from lawyer to CrossFit Invictus 8:25 Invictus as inspiration 10:45 2021 CrossFit Games – embodiment of character 13:45 The power of community 17:40 Authenticity 19:36 Getting to the “why” in coaching 22:30 Kids Helping Kids 28:45 The Fireball Additional Resources: CrossFit Invictus Kids Helping Kids Invictus - William Ernest Henley Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Many of us in functional medicine understand the importance of a healthy GI tract to prevent and reverse underlying chronic conditions. Dr. Peter Kozlowski not only practices and teaches these principles to patients, he also wrote a best-selling book called “Unfunc Your Gut” where he explains the interconnection between the gut and systemic health in a simplified, light-hearted, and engaging way.   In this episode, we get Dr. Koz’s take on the gut immune response, dietary influences, and the vital role of mental-emotional-spiritual health. Today on The Lab Report: 3:00 Meet Dr. Koz and hear his journey to functional medicine 11:15 Dietary changes for big clinical impacts 15:40 Food sensitivity and the GI immune response 18:30 Mental-emotional-spiritual connection to gut health 26:00 Helping patients understand the importance of mental health and the HPA axis 29:20 Intermittent fasting 31:45 How to connect with Dr. Koz 33:10 The clinical impact of the pandemic on GI health 35:30 The Fireball Additional Resources: Koz's website Unfunc Your Gut Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Rachel Gregory is a Board Certified Nutritionist, a health and wellness specialist, author, and the creator of MetFlexLife, a platform that provides educational content as well as coaching services in achieving optimal health. She champions the ketogenic lifestyle, but also advocates for a more tailored approach as opposed to a cookie-cutter method for her clients. Rachel is also the author of the 21-Day Ketogenic Diet Weight Loss Challenge book, a weight loss guide that follows the ketogenic lifestyle with recipes and exercise programs. Rachel joins us to share what it means to be metabolically flexible and how it relates to the ketogenic diet. She describes how she became passionate about training and nutrition. She explains how to make the ketogenic diet work for you and why it’s normal for a woman to struggle with the diet. Rachel also discusses the importance of accountability as well as addressing other points that affect your overall wellness, such as sleep. “Ketosis is not a fad; it is a metabolic state.” - Rachel Gregory This week on The Lab Report Podcast: Who Rachel Gregory is, what she does, and her thoughts on the ketogenic diet. The reason Rachel became fascinated with pursuing a degree in athletic training. Why Rachel decided to switch to a nutrition-focused education. Common misconceptions about the ketogenic diet and ketosis. Why women struggle more with ketosis and the ketogenic diet. Tailoring the ketogenic diet according to a person's profession and lifestyle. Adjustments to make in the ketogenic diet once you reached a certain weight. The importance of having someone hold you accountable for your diet. Developing ‘carb phobia’ in light of the ketogenic trend. Her thoughts on Crossfit and strength training. Addressing sympathetic and parasympathetic balance. Sleep, recovery, stress, and other factors affecting wellness.   Connect with Rachel Gregory: Metflexlife.com Instagram MetFlex and Chill podcast Book: 21-Day Ketogenic Diet Weight Loss Challenge   Subscribe, Rate & Review The Lab Report Thanks for tuning into this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts, Michael Chapman and Patti Devers. If you enjoyed this episode, please head over to Apple Podcasts to subscribe to the show and give us a rating and review. Don’t forget to visit our website, like us on Facebook, and follow us on Twitter, Instagram and LinkedIn. Email Patti and Michael with your most pressing questions on functional medicine. And be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.   Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions of Michael Chapman and Patti Devers and their guests. For medical advice, diagnosis, and/or treatment, please consult a medical professional.See omnystudio.com/listener for privacy information.

Heber Cannon is an accomplished documentary filmmaker who travels the world to capture the fittest people on the planet in action. Along with his partner Marston Sawyer, they are known as the “Buttery Bros” and they have taken YouTube and social media by storm. But, they also ‘walk the walk’ as it relates to health and fitness and are themselves CrossFit enthusiasts. By sitting at the feet of the fittest people in the world, Heber has a unique perspective on health and wellness and an ability to make it fun and entertaining. In today’s episode, Heber talks all things ‘butter’ in the world of diet and exercise, and we hear about his latest film “Resurgence”. Report Today on The Lab: 2:50 Heber Cannon explains his love of butter, fitness, and film making 5:15 How are elite athletes different? 6:30 The importance of nutrition and diet 9:00 Buttery Bros, the brand - on YouTube and everywhere 12:00 The Resurgence of CrossFit 14:35 CrossFit Games 2021 15:45 The Fireball 16:55 Michael needs parenting advice   Additional Resources: butterybros.com Resurgence trailer Buttery Bros - YouTube Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Dr. Sara Gottfried is a key opinion leader as it relates to hormone balance. As a New York Times best-selling author, practicing medical doctor, researcher, university professor, and popular speaker, she offers an evidence-based approach to hormones and nutrition. Her upcoming book “Women, Food, & Hormones” outlines the latest research combined with her vast clinical experience to help women lose weight and get to the root cause of hormonal complaints. In today’s episode, we discuss the interconnection of hormones with diet and the microbiome, and we hear about her approach to bio-identical hormone replacement therapies. Today on The Lab Report: 3:20 Meet Dr. Sara Gottfried and hear her journey to root cause medicine 8:50 Diet, metabolism, and hormones 12:45 Pre-diabetes and continuous glucose monitoring 14:35 Heart rate variability testing and cortisol 17:00 When to use bio-identical hormone replacement 20:20 Cortisol’s effects on other hormones 22:25 The role of the microbiome 25:25 Dosing and timing of hormone replacement 30:50 How you can work with Dr. Gottfried 31:50 The Fireball Additional Resources: saragottfriedmd.com Marcus Institute of Integrative Health Women, Food, & Hormones The Hormone Reset Diet The Hormone Cure Brain Body Diet Younger Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Renaissance Periodization is a one-of-a-kind coaching program. Their team of medical doctors, trainers, dieticians, PhD researchers, and athletes provides an evidence-based approach to athletic coaching and nutrition education to help clients achieve their personal goals. The founder and CEO of this unique company is Nick Shaw, himself a competitive powerlifter, bodybuilder, and coach. On today’s episode, we discuss some practical tips for lifestyle and dietary change with Nick Shaw and learn why Renaissance Periodization is not your ordinary coaching program. Today on The Lab Report: 3:30 Meet Nick Shaw and learn about Renaissance Periodization’s team 6:40 Coaching elite athletes versus the general population 9:00 Caloric restriction for weight loss 13:20 Thoughts on strict diets: keto, carnivore, etc. 15:50 RP Diet Coach app and artificial intelligence 18:30 Motivation, work ethic, and lifestyle change 21:30 Where to start with Renaissance Periodization 23:25 The Fireball   Additional Resources: Renaissance Periodization RP Strength Podcast RP Diet Coach App   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Many of us know insulin as the hormone that regulates our blood sugar. We often think of its role in diabetes. However, insulin affects far more than glucose. Dr. Ben Bikman is a PhD researcher who has been studying insulin for many years. His latest book, Why We Get Sick, outlines how insulin resistance is at the root of chronic disease and ways to treat and prevent it. In this episode, we speak to Dr. Bikman about the mechanisms of insulin resistance, its far-reaching effects in chronic disease, and strategies to improve it. Today on The Lab Report: 2:20 Meet Dr. Bikman and learn why he focuses his research on insulin 8:35 Insulin and insulin resistance   13:55 Where in the body does insulin resistance start? 18:25 Hypertrophic vs. hyperplastic fat cells and the effects of free fatty acids 26:35 Signals that create hypertrophic vs. hyperplastic fat cells 28:45 Muscle-centric model of insulin resistance 32:15 Chronic diseases as they relate to insulin resistance 35:50 Aromatase activity in adipose tissue 37:25 The brain and Alzheimer’s disease as ‘type 3 diabetes’? 41:50 Fasting, ketosis, and lifestyle strategies to combat insulin resistance 47:35 COVID-19, immunity, and metabolic defenses 50:40 The Fireball Additional Resources: Why We Get Sick Ceremides as modulators of cellular and whole-body metabolism Adipose Tissue as an Endocrine Organ Ketones Elicit Distinct Alterations in Adipose Mitochondrial Bioenergetics Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Carey Kepler is a wife, mother, business owner, motivational speaker, top-ranked athlete, and coach. She spends her life helping others to develop a ‘Champion Mindset’ to create and live the life of a champion both inside and outside the gym. Carey teaches the importance of goal setting and the need to continually re-evaluate those goals for success in lifestyle change. In today’s episode, we talk to Carey Kepler about her amazing athletic career and her passion for helping her clients stay motivated and consistent. Today on The Lab Report: 3:20 Learn about Carey Kepler and her lifelong athletic journey 9:15 The Champion Mindset 11:00 Why coaching women is different 13:30 Proper goal setting for change 17:20 Strategies for work-life balance 23:50 Supporting clients through the pandemic 28:35 Want to work with Carey? 30:30 The Fireball Additional Resources: CoachCareyKepler.com CrossFit Central Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Dr. Christian Jenski is a conventionally trained emergency room physician who has made the huge leap to functional medicine. In addition to running a burgeoning practice in Richmond, VA, he keeps his skills sharp by simultaneously working shifts in a busy ER. This gives him unparalleled insight into the way conventional and functional medicine can complement each other. In fact, he believes it has made him a better ER physician. In today’s episode we discuss Dr. Jenski’s approach to functional medicine, how he clinically applies testing, and real-world examples showcasing the power of root-cause medicine. Today on The Lab Report: 3:15 Meet Dr. Jenski and learn about his journey to functional medicine 9:45 Transitioning his practice to functional medicine 12:55 Richmond Integrative & Functional Medicine 16:00 Where to start with testing? 18:05 Case studies using the GI Effects Stool Profile 31:20 NutrEval and Metabolomix + in clinical practice 34:30 Root causes of hormonal imbalance vs. hormone supplementation 39:00 The Fireball Additional Resources: Richmond Integrative & Functional Medicine Hitting Cancer Below the Belt GI Effects Stool Profile NutrEval Metabolomix + Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Functional medicine is all about getting to the root cause of a patient’s complaints. Women’s health can present a unique challenge since hormonal fluctuations need to be considered. Today we meet Julia Glanz. Julia is a registered dietitian with a master’s degree in nutritional science, a certified strength and conditioning coach, and an author. She has an online nutrition practice where she specializes in women’s health and works with women to optimize the key hormones affecting their energy, metabolism, and body composition through strategic nutrition and lifestyle changes. On today’s episode Julia Glanz discusses the role of diet, nutrition, and lifestyle when it comes to optimizing women’s health. Today on The Lab Report: 2:35 Meet Julia Glanz and hear her journey to nutrition and coaching 7:45 Helping a client choose a diet 10:30 Do we need supplements? 13:00 Intermittent fasting in women 16:05 Stress and cortisol in weight gain or causing a plateau 21:10 Mindfulness and food 24:30 Motivation and consistency 28:50 Women’s Guide to Health, Hormones, & Metabolism 32:15 The Fireball Additional Resources: @juliaglanz Instagram The Ultimate Guide To Intermittent Fasting For Women A Woman's Guide To Optimizing Health, Hormones, & Metabolism Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Dr. Saladino is the leading authority on the science and application of the carnivore diet. He has used this diet to reverse autoimmunity, chronic inflammation, and mental health issues in hundreds of patients, many of whom had been told their conditions were untreatable. In addition to his personal podcast, Fundamental Health, he can be found featured on numerous podcasts including The Minimalists, The Joe Rogan Experience, The Model Health Show, Bulletproof Radio, The Dr. Gundry Podcast, The Ben Greenfield Podcast, Dr. Mercola, Health Theory, Mark Bell’s Power Project, and many others. He has also appeared on The Doctors TV show and authored the bestselling book, “The Carnivore Code: Unlocking the Secrets to Optimal Health by Returning to our Ancestral Diet.”   This week on The Lab Report Podcast: Why Paul decided to focus his career on the carnivore diet. What the "Carnivore Diet" is. How the human body responds to plant toxins. The composition of the human diet in the last two million years. How being carnivorous could have helped humans evolve. Paul's thoughts on polyphenols and phytonutrients. What hormesis is and where the idea came from. Why plant compounds have redundant benefits with ignored side effects. Paul's thoughts on short chain fatty acids and the effects of fiber on gut bacteria.   Connect with Dr. Paul Saladino:  Carnivore MD Book: The Carnivore Code Heart & Soil Subscribe, Rate & Review The Lab Report Thanks for tuning into this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts, Michael Chapman and Patti Devers. If you enjoyed this episode, please head over to Apple Podcasts to subscribe to the show and give us a rating and review. Don’t forget to visit our website, like us on Facebook, and follow us on Twitter, Instagram and LinkedIn. Email Patti and Michael with your most pressing questions on functional medicine. And be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.   Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions of Michael Chapman and Patti Devers and their guests. For medical advice, diagnosis, and/or treatment, please consult a medical professional.See omnystudio.com/listener for privacy information.

Ben Greenfield is a fitness guru and NY Times Best Selling author leading the field of human performance and biohacking. His unique voice and influence in the health and fitness industry have paved the way to optimal health for thousands and thousands of people. Ben’s teaching platforms, podcasts, and books offer the latest research on longevity, athletic performance, and anti-aging. On today’s episode, Ben discusses some practical biohacking tips and the importance of identifying and fulfilling your life purpose. Today on The Lab Report: 3:00 Ben Greenfield discusses his fitness journey 10:20 What is ‘biohacking’? 13:10 Practical life changes for optimal health 20:40 Ben’s take on ‘diets’ 27:20 Mindfulness, breathwork, and gratitude practices 30:55 Importance of a purpose statement 34:00 Boundless: Upgrade Your Brain, Optimize Your Body & Defy Aging 36:50 The Fireball Additional Resources: Ben Greenfield Fitness Fit Soul, Fit Body: 9 Keys to a Healthier, Happier You BoundlessBook.com Ben Greenfield Coaching Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Anyone practicing functional medicine, or those patients whose lives have been changed because of it, owe a debt of gratitude to the vision of Dr. Jeffrey Bland. Dr. Bland’s teaching, writing, and research have helped this field to evolve over the past several decades. His latest venture, Big Bold Health, focuses on personalized and global immunity while espousing environmental stewardship. Today we discuss the history of functional medicine, the legacy of Dr. Jeffrey Bland, and his latest work on immunity. Today on The Lab Report: 2:30 Jeffrey Bland on the history and future of functional medicine 8:00 Functional medicine approach to long-haul COVID 13:50 Big Bold Health and personalized immunity 18:05 Global immunity 22:40 The story of Dutch Harbor Omega capsules 26:40 Himalayan Tartary Buckwheat 31:20 Personalized Lifestyle Medicine Institute (PLMI) Additional Resources: Dr. Bland's website PLMI Big Bold Health The Disease Delusion Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.    See omnystudio.com/listener for privacy information.

Many of us struggle with weight and fat loss. But fat, or adipose tissue, has many other functions in the body that may be working against your ability to lose weight. Dr. Sylvia Tara holds a PhD in biochemistry and has dedicated years of research to fat and the ways adipose tissue can work as an endocrine organ in signaling your brain to alter hunger and satiety. Today we discuss Dr. Tara’s book called “The Secret Life of Fat” which outlines the latest information on fat’s role in the body and why you might be struggling with weight loss. Today on The Lab Report: 3:05 Meet Dr. Sylvia Tara and hear why she chose to study fat 6:25 Fat as a villain fueling the growth of the diet industry  9:20 Weight loss myths and fat as an endocrine organ 14:00 Lesser known ways we gain fat and practical tips to control it 18:50 Fasting, circadian rhythms, and obesogens 22:10 Exercise and hormonal signaling to different types of fat 27:55 Weight gain during the pandemic and the mental-emotional component 34:40 Tara’s online program to practically apply these principles 37:10 The Fireball Additional Resources: The Secret Life of Fat Dr. Tara's Online Course Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

REBROADCAST: The basics of mobility often go unnoticed until nagging pain and discomfort arise. Musculoskeletal pain is a very common complaint of many patients. Rather than treating that pain with medication, what if a simple mobility technique could fix the mechanics that caused it? Dr. Kelly Starrett has revolutionized the way we assess and treat common aches and pains by developing a program called The Ready State. His years of working with elite, professional athletes gives him a unique perspective on how to deal with common everyday musculoskeletal issues. In this episode, Dr. Starrett lays out a simple plan that clinicians can use every day to assess and treat their patients with pain. He also discusses some strategies for those with desk-based jobs trying to survive the modern workplace and outlines the basics of good posture. “Pain is the body’s request for change.” – Dr. Kelly Starrett Today on The Lab Report: 2:50 Meet Dr. Kelly Starrett and get introduced to the idea of mobility 8:30 Kelly’s experience with functional medicine 11:00 Adequate vs. Optimal 15:20 What is a supple leopard? 18:50 Prescribing mobility – the movement map 26:25 Deskbound and strategies for the workplace 32:40 Posture and the skill of standing 37:20 The Ready State Additional Resources: The Ready State Becoming a Supple Leopard Deskbound: Standing Up to a Sitting World Ready to Run: Unlocking Your Potential to Run Naturally Waterman 2.0 Muscles and Meridians Stand Up Kids Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Summer is here and with that comes longer days and more sun exposure. The health benefits of sunshine include increased vitamin D production, elevated mood, stronger bones, and even better sleep. However, overexposure to the sun can damage our skin and lead to skin cancer over time. Using sunscreen can help to protect our skin, but where’s the line when it comes to blocking vitamin D production or absorbing potentially harmful chemicals? In today’s episode, we debate the pros and cons of using sunscreen and tell you why you should pay closer attention to what’s actually in it. Today on The Lab Report: 4:35 Sunscreen and the role of the skin 6:10 Types of ultraviolet light 8:40 What about vitamin D? 10:30 Skin cancer, vitamin D, and the sun 13:55 Chemical sunscreens - exposures and toxicity? 18:30 Mineral-based sunscreens as an option Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.    See omnystudio.com/listener for privacy information.