The Lab Report

Stinging nettle (Urtica dioica) is a perennial, flowering plant with many medicinal uses. Not only is it nutrient dense, but it has been used as a diuretic and therapeutically for various inflammatory conditions. However, the plant really does sting! It contains hair-like needles on the leaves and stems to protect itself from herbivorous animals. The injection of histamine and other chemicals causes a local inflammatory response and sometimes paresthesia.   Today we discuss this multi-faceted herb, its nutritional value, and ways to use it medicinally with our favorite herbalist, Greg Monzel.  Today on The Lab Report: 3:00 Stinging Nettle – hey! Let’s call Greg Monzel! 4:20 All about the sting – the good and bad 10:10 Nutritionally speaking 11:35 Important clinical uses of nettles 14:40 Removing and dealing with the sting 17:00 Cooking, tasting, and beer!  18:40 Nettles seeds – waving and renal disease 22:50 The roots! ..... and the stem? 25:50 Wild Persimmon School of Wellness Additional Resources: Stinging Nettle-Light-micrograph Wild Persimmon Wellness Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Chronic Fatigue Syndrome is a complex and evolving illness that is highly misunderstood. In fact, coming to a consensus within the medical community on diagnostic criteria and actual naming convention has been challenging. Newer governing bodies have begun calling it ‘Systemic Exertion Intolerance Disease’ or SEID. Regardless of the inconsistencies, the emotional, physical, and economic impact of this disease can not be ignored. Today we break down the history of ‘chronic fatigue syndrome.’ We also dive into the literature around diagnosis, workup, and treatment options. Today on The Lab Report: 3:05 History of ‘Chronic Fatigue Syndrome’ 6:00 Evolving diagnostic criteria 8:45 Pathophysiology - starting with the brain 10:25 Scienceness, Technocology, and Machinamechanics 11:45 Immunology, HPA axis, autoimmunity, and mitochondrial dysfunction in SEID 13:35 Is there a diagnostic test? 15:15 “What is It?!” 18:35 Treatment strategies and therapies Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Environmental toxins are seemingly everywhere in our daily lives. These synthetic substances which are not usually found in our bodies are known as xenobiotics. Given the ubiquitous nature of xenobiotics and their effects on our health, trying to be mindful of them and avoiding them can seem difficult – especially if you don’t realize they exist! In today’s episode, we discuss three common xenobiotics that can interrupt hormone metabolism, contribute to obesity, and are associated with many chronic health conditions – bisphenol A (BPA), polychlorinated biphenyl (PCB), and phthalates. Today on The Lab Report: 3:35 Defining Terms: Xenobiotics 5:35 What is BPA and why should we care? 8:10 Endocrine Disruptors and Obesogens 10:55 Polychlorinated biphenyl – PCBs 15:25 Phthalates exposure 18:50 What can we do about all of these toxic exposures!? Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Summer is nearly here, and that means backyard barbecue season. Cooking certain foods with high heat causes something called the “Maillard Reaction” – which is a chemical reaction between fat, proteins, and sugars that gives browned and seared foods, like barbecued meats, their flavor. The result of this reaction is the formation of advanced glycation end products or AGEs. High amounts of AGEs have been implicated in many chronic health conditions. In today’s episode, we explain what AGEs are, tell you which foods naturally contain AGEs, and ways to mitigate their harmful effects.   Today on The Lab Report: 3:15 Defining AGEs and the Maillard Reaction 5:50 How do AGEs cause a problem in the body? 7:25 Naturally occurring AGEs 10:15 Patti & Michael “Talk it Out” 13:20 Getting rid of AGEs and mitigating their effects 14:40 RAGEs, AGEs, chronic disease, and therapies 16:20 Question of the Day? Can we get insight on AGE effects using Genova tests? Additional Resources: NutrEval Metabolomix +   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

A very common question we are asked as it relates to functional medicine testing is how medications and supplements affect results. Although we can’t always know the influences, based on physiology and some literature we can make educated guesses. Genova never recommends that any patient discontinue medically necessary medications for the purposes of testing – that decision is up to the ordering clinician. But it might be helpful to discuss what to expect when interpreting results. In today’s episode, we talk about ways medications and supplements can influence results of the GI Effects Stool Profile and how some can interfere with our ability to perform testing. Today on The Lab Report: 3:00 Collection pack instructions and the disclaimer 5:00 Interferents vs. influencers 7:10 Laxatives 10:40 Digestive enzymes 11:50 Better Know a Biomarker 16:40 Antimicrobial meds and supplements 19:20 Proton pump inhibitors and antacids 20:35 Aspirin, NSAID’s, and steroids   22:00 Question of the Day? Where can people access this information for themselves? Additional Resources: GI Effects Stool Profile Test Prep Page Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Bacteria are everywhere in the environment. Although we understand there is a delicate balance of bacteria in our bodies which keep us healthy, many don’t grasp the complexity of how bacterial populations interact, adapt, and survive. They form structures called ‘biofilms’ which have become a hot topic in functional medicine as it relates to treating resistant or recurrent infections. In today’s episode, we dive into the topic of bacterial biofilms- when to suspect them and ways to treat them. Today on The Lab Report: 4:00 What are biofilms? 6:05 EPS, persister cells, and quorum sensing 8:40 Clinical importance and redeeming qualities? 11:35 Treating biofilms 13:20 Antimicrobial lipids 14:55 “What is it?” 18:50 Biofilm take-home points Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

N-acetylcysteine, or NAC, plays an important role in the body when it comes to combating oxidative stress. As a precursor to make glutathione, NAC has been used for decades both as an acute medication and as an over-the-counter supplement. Recently, the line between medication and supplement has been blurred and is now being debated. Today we talk all about N-acetylcysteine - the ways NAC is used and its importance in health and disease. Today on The Lab Report: 2:45 NAC as a drug in acute care settings 4:00 Mechanisms of action in the lung and kidney 7:15 NAC as a daily supplement 10:00 Hmmm…so is it a medication or a supplement? 11:15 Generic drug or herbal constituent? 15:00 Research on NAC in psychiatric disorders 16:16 NAC in polycystic ovary syndrome and fertility 17:40 Safety and side effects 18:50 Question of the Day: What are the other precursors to glutathione and how do we measure them? Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.    See omnystudio.com/listener for privacy information.

Miranda Alcaraz has been a health and fitness influencer for nearly 20 years. As an athlete, entrepreneur, and a busy mom she understands the challenges we all face when trying to fit exercise into our daily schedules. She and her husband Julian created an online fitness community called “Street Parking” offering at-home, daily exercise routines and nutritional coaching to help people achieve their goals through the power of community. Today we meet Miranda Alcaraz, and discuss coaching athletes and non-athletes, pregnant and post-partum women, and her “More than Nothing” approach to consistency and creating habits that last.   Today on The Lab Report: 2:55 Meet Miranda Alcaraz and hear about her journey to fitness 6:50 Lessons learned from injury 9:45 “Street Parking” 11:55 Training athletes vs. non-athletes 14:05 Pregnancy and postpartum fitness 18:25 Fitting in a workout as a busy parent 22:30 Personalizing an approach to nutrition 26:25 The Fireball   Additional Resources:  Street Parking Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Zack George is a top CrossFit athlete, coach, trainer, and author. His journey from overweight teenager to the fittest man in the United Kingdom is a story of resolve and resiliency. We all struggle with motivation and goal setting, but Zack serves as an example of what is possible. Through his online training program “Team Silverback”, his local UK gym, and new book “Start Where Others Stop”, he helps others achieve long-term lifestyle change. In today’s episode, we meet Zack and discuss his athletic success, his challenges, and the importance of setting goals. Today on The Lab Report: 3:25 Meet Zack George and hear about his catalyst for change 8:10 Disappointing injury and turning setbacks into positivity  11:15 Finding a balance with rest and recovery 12:40 Pain and overtraining 14:05 Motivation and goal setting 17:00 Zack’s approach to nutrition 19:25 “Start Where Others Stop”  21:15 Team Silverback and CrossFit BFG 25:45 The Fireball   Additional Resources: Team Silverback Start Where Others Stop CrossFit BFG Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Dr. Ara Suppiah is a pioneer in bringing functional medicine to the professional sports arena. As the Chief Medical Analyst for NBC’s ‘The Golf Channel’, medical contributor to Golf Digest, and personal physician on the PGA and ATP tours, he’s worked with top athletes across the globe to optimize their health and performance using functional medicine principles and testing. Although most of us are not professional athletes, his insight and knowledge when it comes to treating them can translate to practical tips we can all use in our daily lives. Today we learn about Dr. Ara Suppiah’s journey to functional medicine, his approaches to nutrition, rest, and pain, and how he applies Genova’s tests. Today on The Lab Report: 3:40 Meet Dr. Ara Suppiah! 12:15 What sets professional athletes apart? 18:35 Ara loves/hates Michael’s jingles 19:10 Nutrition and using Genova’s testing in professional sports 24:05 Addressing acute and chronic pain 28:35 The importance of rest and recovery 34:10 Ara’s online education programs 37:45 The Fireball Additional Resources: Dr. Ara's website Lose Weight and Feel Great Forever Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

We’ve all had headaches, and some can be severe. Although many people use the words ‘migraine’ and ‘headache’ interchangeably, the physiology and syndrome of migraines is actually a bit different. Rather than suffer with the debilitating nature of migraines, what if there were practical tips to mitigate their effects or prevent them from occurring in the first place? In today’s episode, we define the difference between primary headaches and migraines, we uncover some of the main migraine triggers, and discuss practical tips to help you get to the root cause. Today on The Lab Report: 3:00 Difference between migraines and other headaches 6:30 Food as a trigger 7:30 Hormonal influences on migraines 8:45 The role of the gut-brain axis 9:30 Intestinal permeability, inflammatory cytokines, and SCFA’s 10:30 Neuropeptides, glutamate, CGRP, serotonin 14:55 Logical Speculation – Serotonin and migraines 17:45 Nutritional therapies: Vitamin D, fish oil, and CoQ10 Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Dietary fiber is an important part of a healthy diet and many of us don’t get nearly enough. Research suggests fiber is important for a healthy microbiome and can positively affect many chronic diseases. For as simple as fiber may seem, there are many confusing terms that accompany it – soluble, insoluble, resistant, fermentable, viscous etc. What kind do we need? Why does it matter? In today’s show, we break down the different types of fiber, discuss common food sources, and outline some important health benefits to increasing the fiber in your diet. Today on The Lab Report: 4:05 What is fiber and solubility? 6:10 Insoluble vs. soluble fiber and viscosity    8:45 Clinical uses of each and specific dietary sources 13:20 Fiber’s unique role in the microbiome 16:45 Beneficial systemic effects of fiber in chronic conditions 17:50 Question of the Day How much fiber should we be getting each day? Additional Resources: GI Effects Stool Profile Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Polyphenols are chemical nutrients found in many foods – though mainly in plants. Much of the research in polyphenols surrounds their anti-inflammatory and antioxidant properties. They also have important influences in the microbiome. Dark fruits, red wine, chocolate, green tea, olive oil, and soy are a just a few of the many foods that provide excellent sources of polyphenols. Today we discuss several subclasses of polyphenols, why they are important, and how to get them in your diet.     Today on The Lab Report: 2:40 Defining Terms! 4:30 General health benefits of polyphenols 5:40 The flavonoids 7:45 Anthocyanins, lignans, and stilbenes 9:45 Food court: making the case for bananas, blueberries, and pomegranates 19:25 Question of the Day How do dietary polyphenols affect NutrEval results? Additional Resources: NutrEval Organic Acids Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Behavior change is difficult. Many of us understand that nutrition and movement are important, but how do we take this information to the next level for long-term lifestyle change? Today we meet Meredith Root. She is a very successful and accomplished CrossFit athlete, trainer, and coach. She also has a biological science background and a keen understanding of nutrition as it relates to performance. She co-founded a global nutritional coaching company and helps athletes and non-athletes alike to create sustainable change. In today’s episode, we discuss Meredith’s approach to nutrition and coaching. She offers practical tips that she uses with her clients to support them on their health journey. Today on The Lab Report: 3:00 Meet Meredith Root – hear about her path from scientist to coach 7:15 The Tactical Functional Nutrition program 10:15 Teaching the importance of nutrition 11:30 Diets and fasting in athletes 14:20 Practical tips for maintaining motivation over time 20:20 Meredith’s writing 21:50 The Fireball   Additional Resources: Tactic Functional Nutrition Morning Chalk Up   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Many of us have pets and consider them part of the family. They offer emotional support, companionship, and bonding.  Did you know that they are very important for your health? Beyond pets, the medical field is now recognizing the healing qualities of many types of animals. Animal-assisted therapies are being incorporated into clinical treatment plans to improve health outcomes in many chronic conditions and diseases. Today we dive into the concept of animal-assisted therapy. We take a look into the literature as it relates to psychological outcomes, cardiovascular disease, and more. Today on The Lab Report:  2:35 Pets and the state of the literature 5:55 Effects of animal-assisted therapy in depression 9:42 Animals for anxiety and schizophrenia 11:00 Pet ownership vs. animal-assisted therapy 12:20 Get Outta Here! 14:20 Chickens, neurotransmitters, and hormones 15:50 Biophilia hypothesis 19:00 Question of the Day: What are the differences between service animals, therapy animals, emotional support animals, and working animals? Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Metabolic flexibility is the ability of your body to use whatever food you are eating for energy. In patients with metabolic dysfunction, the body may not be able to adapt well in using different energy sources. Dr. Nathan Jenkins is an integrative exercise physiologist who leads a team of researchers at the University of Georgia studying the effects of exercise on cardiovascular and metabolic health. His team is responsible some of the cutting edge of the latest research around metabolic flexibility. In today’s episode, Dr. Jenkins defines metabolic flexibility, how he measures it in the laboratory, and lays out the state of the most current evidence.   Today on The Lab Report: 3:10 Meet Dr. Jenkins and hear why he studies exercise physiology 8:05 Metabolic Flexibility and how it’s measured 12:08 Fast/slow metabolism and basal metabolic rate 15:40 The importance of postprandial fat oxidation 23:00 Types of exercise on metabolic flexibility 29:20 Maximizing metabolic flexibility by timing food and exercise 32:50 Ketogenic diets and exercise 39:42 The Fireball Additional Resources: Acute exercise effects on postprandial fat oxidation: meta-analysis and systematic review Tabata-style functional exercise increases resting and postprandial fat oxidation but does not reduce triglyceride concentrations UGA Integrative Cardiovascular Physiology Laboratory   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Cinnamon is a spice condiment found in nearly everyone’s kitchen cabinet. It is so versatile in flavoring foods, beverages, candy, and personal care products. But very few of us realize the vast array of medicinal uses for cinnamon. It can be used as a natural supplement to support metabolism, the immune system, the GI tract, and more! In today’s episode, we discuss the many uses for cinnamon and its wide array of potential health benefits. Today on The Lab Report: 3:50 Cinnamon is a powerhouse! 5:05 Insulin, blood sugar, lipids, and oxidative stress 7:00 Eating cinnamon vs. supplementation 8:30 Inflammation and cancer 10:30 Where does cinnamon come from? 13:40 Cinnamon in the GI tract 17:00 Michael’s “side-project” Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Fertility rates have been dropping due to environmental toxicities, higher incidence of obesity and metabolic dysfunction, and couples waiting until later ages to conceive. But it is important to understand that there are many things we can do to improve fertility and optimize preconception health. Dr. Nicole Avena is a PhD researcher who is widely published on the health effects of nutrition. Her most recent book "What to Eat When You Want to Get Pregnant," outlines the latest research on how nutrition can improve fertility and which foods might actually be hindering couples looking to conceive.  Listen in as Dr. Avena discusses which nutrients are important for both men and women when it comes to fertility.  Today on The Lab Report:      3:35    Meet Dr. Nicole Avena and hear why she wrote her latest book     7:15    Important nutrients for fertility     8:50    Testing and physical exam for nutrient deficiencies     9:45    Male fertility, nutrition, toxins    12:55   Are there concerns for vegan and vegetarian patients?     14:30   Seemingly 'healthy' foods which hinder fertility    17:30   Other metabolic concerns    19:35   Sugar in preconception care    20:25   The Fireball    Additional Resources:  Dr. Avena's website What to Eat When You Want to Get Pregnant What to Feed Your Baby and Toddler How Sugar Affects the Brain Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Food labels can be very confusing. In fact, many of us completely ignore them. If you look at the ingredients in many processed foods, you’ve probably tried to pronounce some of the chemical compounds listed in the ingredients. The food industry adds chemicals to food to either enhance flavor and color, or to preserve shelf life. There are thousands of accepted food additives and some may have important health implications. In today’s episode, we discuss just a few additives you might want to keep an eye out for next time you go to the grocery store. Today on The Lab Report: 3:20 MSG – monosodium glutamate 6:40 Nitrites and nitrates 9:55 The “Name that Food” game 12:45 Sulfites are everywhere 13:55 Maraschino cherries are polarizing? 15:20 Sulfites as a top food allergen 16:55 Food colorings, FD&C, lakes, and blue rats 21:25 Artificial vs. natural flavoring Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Animal protein from meat is an important part of a healthy diet. But many of us overlook further using the animal bones to provide additional healing properties. Simmering animal bones over an extended amount of time helps extract minerals, collagen, and other important nutrients into a broth. Bone broth can then be used as stock for other soups or ingested itself to improve health. Listen in as we discuss the many health benefits of bone broth and why you should consider adding it to your diet – oh yeah, we also demonstrate how to make it – kind of. Today on The Lab Report: 2:40 What is bone broth? 5:00 Collagen, glucosamine, chondroitin, and minerals 7:00 Gut healing properties 8:35 Detoxification support 10:00 Amino acids   10:50 Kitchen Cook-cophany! 19:10 How might bone broth effect Genova test results?   Additional Resources: NutrEval GI Effects Stool Profile Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

In functional medicine, we dig deeper to find the root cause of illness and strive to find personalized strategies to optimize health. However, sometimes even that falls short. Dr. Jade Teta has spent over 20 years treating patients, teaching, and writing about health and wellness. He blends biochemistry and philosophy in a way that inspires us to find our true purpose. In so doing, we can all learn how to become “Next Level Human.” In today’s episode, we discuss Dr. Teta’s unique approach to health, diet, metabolism – and philosophy!   Today on The Lab Report: 3:25 Meet Dr. Jade Teta and learn his definition of a Next Level Human 9:25 Integrative endocrinology – a holistic approach to metabolism 12:55 The “Do What Works for You” Diet and the language of metabolism 20:15 Translating diet, lifestyle, and metabolism to patients 24:20 Wearable devices 27:00 ‘Meathead Philosopher’ 31:05 The Lack of Purpose pandemic  39:30 Teta’s online teaching programs 42:50 The Fireball    Additional Resources: jadeteta.com Next Level Human Podcast Human 365 Next Level Tribe The Metabolic Effect Diet   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Neurotransmitters act as chemical signals from our nerve endings to various target cells found in muscles, glands, and other neurons. Although there are many types of neurotransmitters, today we will focus on the catecholamines - epinephrine, norepinephrine, and dopamine. Anyone who has ongoing stress or is an ‘adrenaline junkie’ can attest to the physical effects of the catecholamines. But did you know that they also play a role in our brain’s reward system to make us happy and feel good? Listen in as we discuss the importance of catecholamines, their downstream metabolites, and why we measure them. Today on The Lab Report: 2:10 What is a neurotransmitter? 3:25 Introduction to catecholamines 6:00 Dopamine and the reward system 8:20 Epinephrine, norepinephrine, and the stress response 11:30 Neurotransmitter breakdown and downstream metabolites 16:50 Question of the Day How does caffeine affect catecholamines?   Additional Resources: NutrEval Metabolomix + Organic Acids Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Hormones are chemical messengers in the body that work together to regulate many important functions such as the stress response, growth, libido, and overall metabolism. Although our bodies make many hormones, today we are going to focus on testosterone. Testosterone is a hormone of growth and repair and vitally important for maintaining health. Testosterone levels can naturally fall as we age. Deficiencies, or “low T”, is far more common than many of us realize and the clinical implications are far-reaching in both men and women. In this episode, we discuss all things testosterone, when to suspect deficiencies, and some strategies to improve testosterone levels. Today on The Lab Report:   2:45 What is testosterone and what does it do? 6:15 How is testosterone made? 8:40 Declining levels and deficiencies 9:30 Get Outta Here! 12:10 Signs and symptoms of low T 14:00 What can we do about it? 16:00 Lifestyle modification and natural strategies 21:35 Supplementing with testosterone and downstream metabolism 23:20 Question of the Day Testosterone testing – what’s the difference between saliva, blood, and urine? Additional Resources: One Day Hormone Check Male Hormonal Health Complete Hormones Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

It seems intuitive that being outside in nature is therapeutic and beneficial to our health. What many might find surprising is the amount of clinical evidence supporting nature therapy and the specific physiologic changes that result. ‘Grounding’ and ‘earthing’ are terms that are commonly used these days but even those words under-represent the fascinating biochemical and physiologic effects of nature. In today’s episode, we dive into the different facets of nature therapy, literature to support it, and how being outside can improve health– and hey, its Spring! Perfect timing! Today on The Lab Report: 2:30 Intro to Nature Therapy 4:30 Let’s Define Some Terms! 6:00 “Forest bathing” and urban green space therapy 10:35 House plants and flowers 15:40 Wooden material therapy 16:30 Grounding and earthing – take off your shoes! 19:20 Question of the Day? Which Genova tests might apply to Nature Therapy? Additional Resources: Adrenocortex Stress Profile NutrEval Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

The history of herbal medicine dates back thousands of years. Many of us don’t realize that our current conventional medications come from plants. Greg Monzel is an herbalist who has dedicated his life to keeping the rich history and traditions of plant medicine alive and relevant. In today’s episode, we called on him to help us unravel the mystery of St. John’s Wort. St. John’s Wort is a very commonly used supplement as it relates to mood disorders. But why? How does it work? Where does it grow and how do we identify it?  Listen as we answer all these questions and more. Today on The Lab Report: 6:20 OMG! Greg Monzel is our favorite herbalist 9:55 The basics of St. John’s Wort 11:45 Are there medications growing in your yard? 14:45 What does St. John’s Wort look like? 17:05 Whole plant vs. constituents 19:25 John’s Wort – It’s not just for mood! 23:40 Medication interference and toxicity 27:15 Which constituent of St. John’s Wort is best? 31:45 The Fireball 33:40 What’s in a Name?     Additional Resources: Greg's website - wildpersimmonwellness.com   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Dr. Kien Vuu is a physician, author, and speaker who is on a mission to empower us all to take control of our own health. His personal journey is profound and inspiring. As a young immigrant to the United States, he faced immense challenges which he overcame to become a successful doctor. Then, after developing several chronic diseases, he changed his life and found his way to health and gratitude. Dr. Vuu envisions a world where each of us fully contribute our gifts to humanity with vibrant health and vitality. In today’s episode, we hear the incredible story of Dr. Kien Vuu and he lays out his blueprint on how to live in a Thrive State. Today on The Lab Report: 3:10 Hear the incredible journey of Dr. Kien Vuu 9:30 From chronic disease to health 12:30 Chronic disease as a gift 15:35 The Live Again Project 18:35 Diet Eating styles, bioenergetics, and The Thrive State 25:15 Impact of the pandemic on health and thriving 28:35 The Fireball   Additional Resources: KienVuu.com Thrive State thriveto105.com Live Again project The Unconventional Prescription: YOU are your Best Medicine   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Historically, the field of psychiatry has mainly focused on prescriptive medications and psychotherapy. Though these modalities have saved lives and stabilized many patients, there are often modifiable, underlying root causes to consider. Shae Leonard, PA is a functional medicine physician’s assistant who has spent years changing people’s lives with her functional approach to mood disorders. Today, we talk to Shae Leonard about the effects of nutrition, gut health, hormones, genetics, and movement on mental health.   Today on The Lab Report: 4:35 Get to know Shae and her journey to functional psychiatry 8:00 The gut and other factors as root causes of mood disorders 12:00 Nutrients to optimize mental health 14:15 Using functional medicine testing 15:10 Genetics and epigenetics in mental health 18:20 HPA Axis, stress, sleep, and mood resiliency   24:45 The Fireball   Additional Resources: Shae's Website NutrEval Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Interpreting functional medicine laboratory testing can be intimidating. Dr. Dan Kalish has devoted his career to teaching new functional medicine clinicians how to interpret lab results and where to start when implementing results in practice. His teaching program, The Kalish Institute, mentors and empowers practitioners within a community approach offering many online programs, videos, blogs, and personalized support. In today’s episode, we talk to Dr. Kalish about the importance of nutritional testing, his approach to the NutrEval, and translating results. Today on The Lab Report: 2:45 Meet Dr. Kalish! 3:55 The importance of nutritional lab testing 6:35 Where to start when using NutrEval results in practice 8:20 Functional vs. conventional labs 11:00 Translating to patients and prioritizing treatment strategies 18:30 Teaching the NutrEval and common pitfalls 22:00 Lifestyle factors in functional medicine 24:50 The Kalish Institute 27:20 The Fireball Additional Resources: Kalish Institute NutrEval Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Genova’s nutritional profiles are breaking new ground. The NutrEval, and its subpanels, have been redesigned and reimagined to offer even greater clinical utility! Our nutritional profiles help practitioners identify root causes of dysfunction and treat clinical imbalances that are inhibiting optimal health. These advanced diagnostic tools provide a systems-based approach for clinicians to help their patients overcome chronic conditions and live a healthier life. On today’s episode, we discuss the new features of the upgraded NutrEval report and give some clinical insight into the new biomarkers and functional pillar scoring system. Today on The Lab Report: 2:00 – Welcome to the brand new NutrEval 3:14 – Nutrition & Functional Imbalances 4:23 – The 5 Functional Pillars 6:04 – Nutritional Needs Assessed on the NutrEval 7:39 – Pathways, Mitochondrial Dysfunction, and Oxidative Stress 9:16 – The Organic Acids 11:29 – Better Know The New Biomarkers 13:07 – Google It: Is Corn a Vegetable? 14:32 – alpha-hydroxybutyric acid & oxalates 17:02 – Organic acid categories 19:24 – The Amino Acids 21:14 – The Fatty Acids 23:08 – Nutrient & Toxic Elements 24:07 – Question of the Day: Updates to other Nutritional Profiles? Additional Resources: Nutrition - Redesigned, Reimagined Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Dr. Patrick Hanaway is a key thought leader and educator in functional medicine. After decades of work, his contribution and influence in our field continues to this day. His task force leadership at IFM during the pandemic helped to shape the functional medicine approach to COVID-19.  Also, as prior Chief Medical Officer for Genova Diagnostics, he helped to create the NutrEval Profile as we currently know it. In today’s episode, we discuss what we’ve learned over the past year regarding COVID-19, and the how functional medicine approach can improve outcomes. We also get his take on the new NutrEval and how to use it in practice. Today on The Lab Report: 2:45 Welcome back Dr. Hanaway! 4:25 What have we learned about COVID-19? 12:45 Nutrient supplements during the pandemic 18:41 Functional approach to SARS-CoV-2 20:45 The NutrEval in practice 30:00 Can we get all we need from a balanced diet? 36:30 Systems-based interventions in chronic disease 42:40 Relationships and connection while in lock-down 49:30 The Fireball   Additional Resources: IFM COVID Resources Dr. Hanaway's Website: Family to Family NutrEval Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Oxalates are organic acids that can be made in the body, but they are also found in various foods. Many people associate oxalates with a risk for kidney stones. There are many claims about the dangers of oxalates and the need to avoid high oxalate foods. But, are these claims valid? Should we be afraid of oxalates? Why should we measure them and what do they mean? In today’s episode, we dive into the biochemical glyoxylate pathway. We also explain how the body makes and metabolizes oxalates, the role of the gut microbiome, and how to interpret oxalate levels. Today on The Lab Report: 4:15 The Glyoxylate Pathway - what is an oxalate? 6:35 Glyoxylate is the hub! 8:50 Two off-shoots of glyoxylate: oxalic acid and glycolic acid 9:50 Oxalic acid – kidney stones and beyond 14:07 Logical Speculation: Oxalic Acid and Metabolic Syndrome – cause vs. effect 16:50 Glycolic acid, glutathione, and oxidative stress 19:30 Glyceric acid 21:00 Question of the Day What is systemic oxalosis and should we be worried about it? Additional Resources: Glyoxylate Pathway Chart Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.    See omnystudio.com/listener for privacy information.

Dr. Filomena Trindade has been practicing and lecturing about functional medicine for over 25 years. She has been a leading expert in diabesity and metabolic medicine. Additionally, Dr. Trindade’s mentorship programs and teaching style have been transformative for many clinicians new to this field. We often find in functional medicine, that inadequate nutrition can be the root cause of chronic medical conditions. And, during the global pandemic, this becomes vitally important as patients and clinicians are looking to optimize immunity. In today’s episode, we talk all things nutrition and discuss the role of specific nutrients in immunity and optimal health. We also discuss the role of mentorship in practice implementation. Today on The Lab Report: 2:40 Azores and archipelagos 3:35 Welcome back Dr. Filomena Trindade! 6:15 Optimizing immunity, nutrition, and COVID 12:20 Supplements, food sources, and root causes 15:05 Carbs and CGM 17:30 Saturated fat, cooking oils, and eating farm-to-table 22:40 Ketosis, fasting, and metabolic flexibility 24:30 The importance of mentorship 30:40 The Fireball Additional Resources: Dr. Trindade’s website NutrEval Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

What are free radicals and oxidative stress? How do free radicals impact the health and wellness of our patients? Why should clinicians analyze and measure a patient’s free radicals and oxidative stress levels? What can this information tell us about our patient’s overall health and their risk of developing a chronic disease? Today, we simplify the complex topic of free radicals and their connection to oxidative stress. We discuss the benefits and drawbacks of free radicals in your body and how antioxidants can help you decrease them while eliminating oxidative stress levels. We discuss what commonly causes free radicals to develop in your body and where we can find the best sources of antioxidants. We also discuss the connection between chronic diseases and high levels of free radicals as well as the correlation between extreme exercise and significant weight loss to increased levels of oxidative stress.   “When we talk about oxidative stress, it’s really when the damage outweighs your ability to counter it with antioxidants.” - Patti Devers   This week on The Lab Report Podcast: Understanding what ‘free radicals’ are and their connection to oxidative stress The pros and cons of free radicals How antioxidants help reduce oxidative stress The main sources of antioxidants The primary causes of free radicals in your body The connection between certain chronic diseases and high levels of oxidative stress How to measure oxidative stress What SOD’s and glutathione do within the body Debunking the misconception around ‘burning through your glutathione’ Taking glutathione supplements and what to consider before starting a glutathione supplement How excessive exercise and significant weight loss can elevate your oxidative stress levels The correlation between glutathione levels and pyroglutamic acid   Question of the Day: When trying to assess heavy metals in a patient, is it better to use a urine test or a blood test?   Subscribe, Rate & Review The Lab Report Thanks for tuning into this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts, Michael Chapman and Patti Devers. If you enjoyed this episode, please head over to Apple Podcasts to subscribe to the show and give us a rating and review. Don’t forget to visit our website, like us on Facebook, and follow us on Twitter, Instagram and LinkedIn. Email Patti and Michael with your most pressing questions on functional medicine. And be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.   Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions of Michael Chapman and Patti Devers and their guests. For medical advice, diagnosis, and/or treatment, please consult a medical professional.See omnystudio.com/listener for privacy information.

When it comes to the gastrointestinal tract, we often focus on the balance of the commensal bacteria to optimize health. But, if that balance is interrupted, or the microbiome is lacking, some of the bacteria can overgrow. At higher levels of growth, patients can experience symptoms. There are also some important disease associations with overgrowth of specific species. Because of this potential, we designate these aerobic bacteria as potential pathogens. On today’s episode, we unpack the concept of potential pathogens and talk about what to do- and what not to do- when you find them on a stool test.     Today on The Lab Report: 2:55 Potentially pathogenic bacteria – what are they and when should we worry? 7:30 Klebsiella - symptoms and systemic associations 10:52 Why you don’t always treat a potential pathogen 12:25 Concerns about Proteus 14:40 Citrobacter is common but has potential 15:45 Let’s Recap! 17:00 Question of the Day with Jim Kelton! What does 1+, 2+, 3+, 4+ mean on the GI Effects culture results?   Additional Resources: GI Effects Comprehensive Stool Profile Pathogenic Bacteria & Yeast Chart   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Taylor Dukes is functional medicine nurse practitioner with a burgeoning practice and growing online social media presence. Her expertise is vast - working with women in prenatal and postnatal care, helping professional athletes optimize performance, and improving the health of thousands of patients including CEO’s and celebrities. On today’s show, we discuss her journey from conventional to functional medicine and her unique approach to wellness. Today on The Lab Report: 3:20 Meet the fabulous Taylor Dukes 6:50 Taylor’s approach to fertility and postnatal care 10:05 Implementing functional medicine testing 11:25 Where to start with professional athletes 13:55 Telemedicine in practice 16:20 Work/Life balance for working moms 18:30 The Fireball Additional Resources: Taylor's website Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Kara Collier is a registered dietician who specializes in continuous glucose monitoring (CGM). CGM is a wearable device that measures glucose levels throughout the day to evaluate your body’s response to dietary changes, stress, and exercise. Knowing this information can help you make personalized dietary and lifestyle changes to prevent metabolic dysfunction down the road or improve your current health.  On today’s episode, Kara explains the importance of CGM. We also discuss various patterns that might be seen and things you can do to optimize your daily choices.   Today on The Lab Report: 2:50 Kara Collier on her journey to nutrition technologies 6:15 What is CGM and how is NutriSense different? 11:00 Spike, area under the curve, average glucose variability 15:20 Glucose and stress/exercise 17:50 Ketogenic diets and CGM 19:35 Asymptomatic hypoglycemia 21:00 CGM in the menstrual cycle and interpersonal variability 25:55 The Fireball   Additional Resources: NutriSense   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Using temperature therapeutically is becoming increasingly popular. Saunas and cold immersion ice baths are being touted in the biohacking community for overall longevity. Published research surely backs this up. The health benefits of thermogenesis and sauna are seen in cardiovascular disease, mood disorders, immune optimization, detoxification, and many other clinical conditions. Today we discuss sauna and cold immersion with Andrew Nehlig and Jennifer Richter. They own and operate ‘Sauna House’, a premier Nordic-styled bathhouse located in Asheville, NC. They are passionate about their work and share their insight regarding the health benefits of sauna.   Today on The Lab Report: 3:00 Meet Andrew and Jen! 7:30 Different types of sauna 10:00 Amazing health benefits 14:15 How long? How often? Too much?  19:45 Immunity and sauna 21:23 Temperature therapy and mood 25:25 Hot then cold or cold then hot 29:05 The Fireball   Additional Resources: Sauna House Sauna, Heart Disease, and Decreased Mortality Immunity and Temperature Therapy   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

The art of the physical exam is often overlooked in favor of testing. Although Genova’s nutritional profiles are designed to uncover subtle nutrient insufficiencies, there are many physical hints and clues which can give additional insights and perhaps lead you to consider testing. The areas of the body with rapid cell turnover are the first places to manifest these subtle changes. On today’s episode, we resurrect the physical exam and review findings which may reflect your patient’s nutritional status. Today on The Lab Report: 3:35 Is the physical exam dead? 5:25 Global observations 7:00 Hair and scalp 9:45 Mouth – tongue, gums, and dentition 15:35 Let’s Define Some Terms! – ‘Erythematous’ 16:30 Skin bumps and rashes 18:50 Fingernails 21:00 Question of the Day How long does it take to reverse these findings with supplementation? Additional Resources: NutrEval Metabolomix+   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Small intestinal bacterial overgrowth (SIBO) is a common underlying cause of irritable bowel syndrome (IBS).  Bloating, constipation, diarrhea, excessive gas, or nausea are all hallmark SIBO symptoms. When it comes to diagnosis, the gold standard is endoscopic small bowel aspiration. This method is invasive, inconvenient, and not without risk. Breath testing and stool testing are now more commonly used. Today we dive into some specific patterns seen on stool testing that may point toward a SIBO diagnosis in symptomatic patients.   Today on The Lab Report: 2:50 IBS and bacteria in the small intestine 6:15 Symptoms of SIBO 7:35 Stool testing for IBS 9:05 Commensal abundance 10:00 Digestion and absorption markers 12:30 What do we think we know? Pancreatic elastase 1 and SIBO 16:35 Gut metabolites 17:50 Methanobrevibacter smithii and methane dysbiosis 19:50 Bacterial culture 20:50 Question of the Day How does methane slow transit time? Additional Resources: GI Effects Comprehensive Stool Profile   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Cellular respiration is the process of converting our food into energy to fuel the body. It involves many biochemical reactions to create a molecule called adenosine triphosphate (ATP) - our main energy source. When it comes to ATP production, many of us think about the Krebs Cycle not realizing it is only part of the story. The Electron Transport Chain bears the brunt of the work to keep our cells alive and our bodies functioning optimally. Although biochemistry can seem challenging, in today’s episode we break it down into simplistic terms and explain why you should care about it. Listen as we discuss the importance of the electron transport chain. Today on The Lab Report: 2:15 Basic overview of cellular respiration and ATP 4:50 Breaking it down 7:45 The Krebs Cycle and NADH/FADH2 8:30 Electron Transport Chain and the bucket brigade 10:55 ATP Synthase is cool 13:20 High-level recap 14:15 Oxidative stress and CoQ10 17:30 Question of the Day: Who is Krebs? Additional Resources: ATP Synthase in action NutrEval Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.                                                                                                                See omnystudio.com/listener for privacy information.

Due to the pandemic, many of us are working from home, and looking to optimize our immunity. The behavioral and lifestyle changes we promote in functional medicine are key to having metabolic flexibility and immune system resiliency. However, there are supplements and herbs often used to improve the immune response. Astragalus is a root that has been used in Traditional Chinese Medicine for hundreds of years as it relates to infectious disease. Today, we dive into herbal medicine and discuss the many health benefits of astragalus. Today on The Lab Report: 3:20 Tinctures and extracting medicinal herbs 6:10 What is astragalus and why would we take it? 8:40 Plants are the basis for all medications 10:10 Astragalus – mechanism of action                                   13:30 What’s in a Name? 15:50 Question of the Day? How do herbal supplements affect test results?   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.                                                                                                              See omnystudio.com/listener for privacy information.

In functional medicine, the focus is on getting to the root cause of disease. Sometimes subtle nutritional insufficiencies can result in significant clinical consequences. By measuring steps in biochemical pathways called organic acids, we can uncover nutrient cofactor needs. One important biochemical process is the kynurenine pathway. The enzymes involved are highly dependent on vitamin B₆. Knowing this, abnormal organic acid levels within the kynurenine path can reveal vitamin B₆ insufficiencies. In addition, this pathway and its metabolites have important clinical implications. In today’s episode, we discuss the importance of the kynurenine pathway, what each step means, how we measure them, and what you can do about it. Today on the Lab Report: 2:35 The kynurenine pathway starts with tryptophan 5:15 What’s the end product and what drives this metabolism? 9:20 Kynurenic acid and NMDA receptors 11:30 Xanthurenic acid elevations 12:15 Quinolinic acid and why we worry about it 13:35 Ratio between KA and QA 14:35 Logical Speculation: Serotonin Tryptophan Steal 18:35 How and where we measure these organic acids 19:25 Question of the Day What about serotonin metabolites? Additional Resources: NutrEval Metabolomix+ Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Dietary fat is broken down into fatty acids in our body. Fatty acids are important for many bodily functions including energy production, making cell membranes, and for signaling the inflammatory cascade. Among the several types of fatty acids, omega-3s have special benefits. Many people take supplements containing them in the form of fish oil. But, why? Can we get omega-3s in food? Why do we need them? How are they beneficial? In today’s episode, we introduce the omega-3 fatty acids. We discuss their naming convention, their health benefits, and we single out a few of the main players. Today on The Lab Report: 2:55 What is a fatty acid and where do those names come from?   7:05 The benefits of omega-3s 8:25 Dietary sources 12:05 Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA) 14:00 Supplementing with fish oil 17:35 Better Know a Biomarker 22:10 Question of the Day How do we decide which fish oil supplement is best? Additional Resources: NutrEval Metabolomix+ Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

We live in a toxic world. Every day we are exposed to an array of environmental toxins in our air, water, soil, and food. Luckily, our body is well-equipped to handle most of them. Additionally, there are things we can do to help optimize the body’s detoxification process. Not only should we try to avoid toxins whenever possible, but we can also support the process of detoxification by focusing on nutrition, the GI tract, our skin, and proper hydration. In today’s episode, we review steps in the body’s process of detoxification and speak to Dr. Christine Stubbe of Genova’s Medical Affairs team on her personal detox protocol. Today on The Lab Report: 3:00 Exposures and the bucket analogy 5:30 Weight loss and toxin release 6:25 Physiologic steps of detoxification 10:35 Getting specific on detox protocols with Dr. Stubbe 16:25 The importance of preparation  19:45 Christine’s daily protocol 36:30 Question of the Day Which Genova testing profiles give insight into detox potential? Additional Resources: GI Effects Stool Profile Methylation Panel Detoxigenomic Profile Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.      See omnystudio.com/listener for privacy information.

Our daily lives are filled with toxic exposures which can affect our health. Luckily, our bodies are well-quipped to handle and detoxify most of them. However, excessive exposures can lead to some subtle clinical presentations and eventually serious physical side effects. In today’s episode, we discuss the sources of three common metal exposures, their physiologic importance, and how to test for them. Today on The Lab Report: 3:05 Biotransformation -defining terms 7:00 Why do we care about heavy metal exposures?   9:05 Lead 13:30 Mercury 16:50 Arsenic 20:15 Genova testing options 24:20 Question of the Day: What form of mercury is being measured on the NutrEval? Additional Resources: Agency for Toxic Substances and Disease Registry (ATSDR) NutrEval Elemental Analysis Comprehensive Urine Elements Profile   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.    See omnystudio.com/listener for privacy information.

Drew Manning is a health and fitness expert who became a world-wide sensation with his Fit2Fat2Fit experiment years ago. He gained and lost 75 pounds on purpose to understand the psychology of weight loss and bring empathy to the fitness industry. Currently, he is in the midst of repeating this feat as he turned forty years old in his Fit2Fat2Forty experiment.  Drew is halfway through after gaining 60 pounds and is about to journey back to fit. Today we check in on how he’s feeling and discuss what he’s learned so far. Today on The Lab Report: 4:35 Drew Manning discusses the physical and emotional toll of weight gain 8:25 Empathy   9:25 The difference after turning 40 11:05 Social media influence 13:05 The effects of ‘dirty diets’ 16:00 Preparing for the journey back to fit 18:40 Television series? Book? Documentary?   19:35 The Fireball Additional Resources: Back2Fit Fit2Fat2Fit Experience Podcast Fit2Fat2Fit: The Unexpected Lessons from Gaining and Losing 75lbs on Purpose Complete Keto   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

As the year 2020 comes to a close, Patti and Michael reflect back on the past year of The Lab Report podcast, which is approaching one year old. This new educational platform was created to spread the word about functional medicine and promote a focus on health and wellness. Throughout the year, we’ve covered many topics and interviewed some amazing guests. We laughed a lot and learned so much along the way. As we head into the New Year, many people make resolutions to improve their health. In today’s episode we reflect on past shows and highlight some clinical pearls to help guide you into a healthy 2021. Today on The Lab Report: 2:25 Back to the very beginning 5:10 What did we learn about diets? 13:00 Who doesn’t love jingles? 14:35 Movement, exercise, and motivation 19:55 Mindfulness and stress 23:00 Ok, now what? Where do you start?   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Dr. Austin Perlmutter is a board-certified internal medicine physician and New York Times best-selling author of the book Brain Wash. He has a special interest in helping patients understand their decisions and behavior as it relates to improving their health. Understanding unconscious habits and how the brain processes our environment is pivotal when it comes to helping patients and guiding their treatment – especially as many of us are making New Year’s resolutions. In today’s episode, Dr. Perlmutter explains the ‘why’ behind our unhealthy decision-making and offers some strategies to change our behavior. Today on The Lab Report: 2:40 Meet Dr. Perlmutter and learn about his focus on the brain 6:40 Prioritizing what’s good for us – knowledge, willpower, and blame 10:40 Freedom of choice and unconscious habits 15:30 Breaking the cycle of bad habits for the New Year 18:55 The effect of social media and news distractions 22:30 Protecting our brain – Brain Wash 27:45 The immune system beyond infectious disease 32:25 The Fireball Additional Resources: Brain Wash: Detox Your Mind for Clearer Thinking, Deeper Relationships, and Lasting Happiness The Modern Brain - Psychology Today drperlmutter.com Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

We tend to lean on traditions during the holiday season. As they are handed down through the generations, their origins are often forgotten. Not only do traditions offer comfort and help to unify us, but many also have important health benefits. Today we have some fun with the origins of several holiday traditions and weave in their clinical significance. Make sure to stay tuned for a special Genova version of ‘Twas the Night Before Christmas!   Today on The Lab Report: 2:50 Mistletoe – antioxidants and smoochie smoochie 5:00 Pine, conifers, and evil spirits 7:35 Peppermint candy canes and carminatives 10:35 Checking in with the UK – Oliver’s fear of figgy pudding 14:40 Gingerbread houses made from the super-herb 17:40 Gift-giving and ‘Off the Cuff’ with the Medical Affairs team 24:55 ‘Twas the Night Before Christmas ???????   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

Vitamin D is a fat-soluble vitamin with important physiologic effects. Unlike other vitamins that must be obtained from the diet, vitamin D can also be produced in the skin from sunlight. The health implications of vitamin D have been widely studied and some of these effects might surprise you.   In today’s episode, we describe how vitamin D is metabolized and why it is clinically important in the body. We also discuss supplementation and the confusion around optimal levels.   Today on The Lab Report: 2:45 Let’s define some terms! 5:10 Metabolism and activation of vitamin D 6:30 Difference between vitamin D₂ and D₃ 8:50 The role of sunlight 10:00 VDRs, calcium homeostasis, and immunity 14:50 Vitamin D in glucose metabolism and effects in the brain 17:30 What are optimal levels? 20:45 Question of the Day: Can you get too much vitamin D?   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected]. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.    See omnystudio.com/listener for privacy information.