Sigma Nutrition Radio

Dr. David Nunan, PhD is a Lecturer and Senior Research Fellow in the Centre for Evidence-Based Medicine at the University of Oxford. There, he is the Director of the Postgraduate Certificate in 'Teaching Evidence-Based Health Care' and the lead tutor for the internationally-renowned 'Teaching Evidence-Based Medicine' course. He is a principal investigator with research interests in prevention and treatment of lifestyle-related conditions, improving the understanding and use of research evidence, and meta-epidemiology (research on research). David has experience in a breadth of methodologies including diagnostic studies, statistical analysis, qualitative research and clinical trials. Show notes available at sigmanutrition.com/episode416

Bruce Neal is Executive Director at The George Institute for Global Health Australia; and Professor of Medicine, UNSW Sydney. Prof Neal is a UK-trained physician who has 25 years' experience in clinical, epidemiological, and public health research with a focus on heart disease, stroke and diabetes. Bruce has a longstanding interest in high blood pressure and diabetes and the potential for both clinical interventions and changes in the food supply to deliver health gains. His work has been characterised by its focus on collaboration, quantitation, translation and impact. He holds professorial appointments at UNSW Sydney, Imperial College London, and an honorary appointment at the University of Sydney. He has published some 450 scientific papers and since 2016 has been identified by Thomson Reuters as one of 'The World's Most Influential Scientific Minds', an acknowledgement provided to just a few thousand researchers across all disciplines, worldwide. He has particular expertise in the conduct of large-scale clinical trials addressing cardiovascular disease but has also done a significant body of work addressing food policy issues related to sugars, fats, portion size and food labelling. Find the show notes at sigmanutrition.com/episode415/

In this episode, the Sigma team discuss the claim that machine learning and data science may overtake traditional research methods in nutrition. They discuss how machine learning could solve some current limitations of traditional methods, studies on its use so far, potential applications in future trials, and potential limitations or problems with the increased use of data science (including ethical and societal concerns). They also ponder on how tech is currently being used (and abused) in relation to personalised nutrition, tech products, continuous glucose monitoring use, among other things.

" data-userid="424351203778215936" data-orgid= "425311536639447040">Anthony Fardet, PhD is a nutrition science researcher in the Human Nutrition Unit at Université Clermont Auvergne, France. His work has focused on a number of related areas; the consequences of the reductionist and holistic approaches applied to nutrition research, the relevance of a new classification of foods based on their degree of processing, and the role of the complex structure of the food in its health potential ("matrix effect"). You can find the show notes to this episode at sigmanutrition.com/episode413/

" data-userid="424351203778215936" data-orgid= "425311536639447040">Dr. Eirini Dimidi of King's College London discusses the research on diet in chronic constipation and functional bowel disorders. Dr. Dimidi is a Lecturer in Nutritional Sciences and a Registered Dietitian. In 2016, she was appointed as a Research Associate at King's College London, where she undertook several research projects on the impact of nutritional interventions in gut function and dysfunction. " data-userid="424351203778215936" data-orgid= "425311536639447040">Dr. Dimidi is undertaking research on nutrition-based interventions, including fibre, plant foods, prebiotics, probiotics, and the low FODMAP diet, in gastrointestinal health. Her primary focus is to advance the understanding of the impact of dietary therapies in functional bowel disorders, including chronic constipation and irritable bowel syndrome. " data-userid="424351203778215936" data-orgid= "425311536639447040">You can find the show notes to this episode at sigmanutrition.com/episode412/

Click here to subscribe to Sigma Nutrition Premium In this episode Alan and Danny discuss the role of nutrition in bone health. They cover the importance of bone health, bone disorders such as osteoporosis, how nutrients play a role in bone remodelling, and the evidence of dietary and supplementation trials on bone health outcomes. You can find the show notes, with links to all the reference studies, at https://sigmanutrition.com/episode411/ Click here to subscribe to Sigma Nutrition Premium

In this episode Alan and Danny answer a variety of questions sent in from listeners. Questions: [1:10] Gabriel - Is there any benefit to including SFAs and cholesterol in low quantities in our diets for healthspan? [10:42] Luis Arrondo - Can I do 3 rather than 4 meals or more for protein absorption by increasing grams of protein? How many grams of protein can be absorbed at one sitting. Does taking in protein at night help more absorption of protein? If so, something slower, like milk over whey? Last, how much protein per kilo of weight to gain muscle via weightlifing? [19:34] Heather Smith - Please could you go into the sodium needs of those with hypotension. Your podcast about normotension and hypertension was excellent, as was the section relating to athletes. I'd love to hear your thoughts on the sodium needs of a hypotensive person. Thank you! [27:00] Judith Williams - I would find it really helpful if you could summarise what the evidence shows are the key dietary changes for long term weight loss. [36:41] Dale Grant - Great podcast and episode as normal especially the quack asylum (big fan of this segment). Having listened to a few of these extreme people (quacks) on various platforms, I've noticed they also employ an aggressive falsify my opponents position tactic. Its almost as if they are aware of Karl Poppers falsification principle, but have misinterpreted it as falsify my "opponents" position instead of my own. Aside from the fact they falsely view the person they are having a debate with as their "opponent", they miss the point that they should be trying to find evidence to falsify their own position, and thus get closer to a capital T Truth. On the other hand as Alan pointed out with Assem Mahlhotra, this may just be a reluctance to acknowledge evidence for other reasons (narcissism, us vs Them narrative, etc). Nowhere was this more apparent than when James Wilks (host of mass propaganda film game changers), sought to aggressively debate Chris Kresser on the Joe Rogan Podcast. Considering Wilks is a former cage fighter this wasn't surprising. Unfortunately, this aggressive tactic does lead some people to conclude that Wilks has "won" the argument, because he has "won" the debate. Similar to most modern debates, it seems like you don't have to win the debate intellectually with reason. Instead you just have to make it seem as if your more competent than your opponent. Do you agree these extreme people employ this tactic? and how do you think we could improve "scientific" debates (note inverted commas) in the public domain in the future? [46:40] Dimitri - Should fruit consumption be moderated because of the sugar content? For example, a fig has 8g of sugar, can I eat 5-10 in one sitting or would that be detrimental to health? [51:26] Rebecca Toutant - What is the evidence / practice behind integrative and functional nutrition? [56:06] Duncan Clarke - This will be a strange question for you but I'll send it anyway. How could a cyclist specifically lose upper body muscle mass? For example a fit healthy athlete from another sport takes up cycling and they now have more arm/shoulder muscle than needed. The goal being to maximize the power to weight ratio for climbing. [60:15] Gabriel - Do you foresee any public health issues related to the increasing popularity of plant based diets, where less careful individuals may face issues consuming certain nutrients harder to get from a plant based diet, such as preformed Vitamin A, choline, iron, protein etc? [72:03] Ward Stanford - After re-listening to your podcast on weight maintenance over time I was wondering what information exists on the idea of establishing new body fat set points. It seems like merely existing at a lower bf% for a period of time may not be enough, but what are your thoughts on one's ability to truly create a lower set point where it becomes easier to maintain a lower body fat, and how long would you need to be at that lower bf% for it to become a "set point" Thank you!

" data-userid="424351203778215936" data-orgid="425311536639447040">In this episode nutritionist Simon Hill discusses the barriers to eating a healthy diet, steps that can be taken to shift both individuals and the general population to a healthier dietary patten, and a number of other topics. Find the show notes at sigmanutrition.com/episode409/

or you can support the show on " data-userid="424351203778215936" data-orgid= "425311536639447040">Dr. Mario Kratz is a clinical researcher in the areas of nutrition, obesity, and cardiometabolic disease, with more than 20 years of experience running clinical studies in a variety of populations. He is a former research associate professor at the University of Washington in the departments of Medicine and Epidemiology. And is also formerly an Associate Professor at the Fred Hutchinson Cancer Research Center in Washington state. or you can support the show on " data-userid="424351203778215936" data-orgid= "425311536639447040">You can find the show notes at sigmanutrition.com/episode408/ or you can support the show on patreon.com/sigmanutrition/

In this episode we discuss the potential impact of dietary polyphenols on cardiovascular disease risk; including impacts on blood pressure, flow-mediated dilation, and other related outcomes. We talk about some potential mechanisms and then several specific randomized, controlled trials. You can find the show notes at sigmanutrition.com/episode407/ and you can support the podcast on patreon.com/sigmanutrition

In this episode we discuss the potential impact of dietary polyphenols on cognitive health; including cogitnitve funciton, memory, and risk of dementia and Alzeimher's. We talk about some potential mechanisms, cohort studies, and then direct controlled trials. You can find the show notes at sigmanutrition.com/episode406/ and/or support the podcast at patreon.com/sigmanutrition

and you can support the podcast at " data-userid="424351203778215936" data-orgid="425311536639447040">Dr Adrian Brown is a NIHR Lecturer and Research Fellow in the Centre of Obesity Research at University College London. He is also a senior Specialist Weight Management and Bariatric dietitian with over 15 years of clinical experience and a PhD in Medicine from Imperial College London. and you can support the podcast at " data-userid="424351203778215936" data-orgid= "425311536639447040">His research interests centre around obesity, type 2 diabetes, bariatric surgery, weight stigma and the use of formula-based diets in different patient populations. He is an Honorary Academic for Public Health England Obesity and Healthy Weight Team, on the strategic council for APPG on Obesity and is on the scientific council of the British Nutrition Foundation. and you can support the podcast at " data-userid="424351203778215936" data-orgid= "425311536639447040">You can find the show notes to this episode at sigmanutrition.com/episode404/ and you can support the podcast at patreon.com/sigmanutrition/

and you can support the podcast at " data-userid="424351203778215936" data-orgid= "425311536639447040">Prof. Marion Hetherington is Professor of Biopsychology at University of Leeds, where her research is focused on the psychology of appetite across the lifespan. She has previously been at Johns Hopkins, the NIH, the University of Dundee, University of Liverpool and Glasgow Caledonian University, before taking up her role in Leeds in 2008, where she works within the Human Appetite Research Unit. You can find the show notes to this episode at sigmanutrition.com/episode404/ and you can support the podcast at patreon.com/sigmanutrition

" data-userid="424351203778215936" data-orgid= "425311536639447040">Prof. David Jacobs, PhD is Professor of Public Health, in the Division of Epidemiology and Community Health, at the University of Minnesota. He has published highly inflential work in nutritional epidemiology and health epidemiolgy for decades. A number of his papers have brought up crucially important ideas about how to do good nutrition science. Specifically, he has talked about think of whole diet or foods as the exposure of interest, rather than individual nutrients. Essentially warning against the pitfalls of applying a biomedical lens to nutrition research. You can find the show notes to this episode at sigmanutrition.com/episode403/

" data-userid="424351203778215936" data-orgid= "425311536639447040">Prof. Leanne Redman is a Professor of Reproductive Endocrinology & Women's Health, based at the Pennington Biomedical Research Center. As the director of the Reproductive Endocrinology and Women's Health Laboratory, she is focused on understanding the intergenerational transmission of obesity. She has published on maternal diet, preeclampsia, and gestational diabetes, amoung other issues. She and her colleagues are currently conducting a rigorous trial to determine the effects of a 6-month gestational intervention with calorie restriction and food provision to promote maternal weight maintenance and fat loss in 100 pregnant women with grades 2 and 3 obesity. " data-userid="424351203778215936" data-orgid= "425311536639447040">Show notes are available at sigmanutrition.com/episode402/ " data-userid="424351203778215936" data-orgid= "425311536639447040">You can support the podcast at patreon.com/sigmanutrition/

We take a look at three more "quacks" who spread misinformation; Dr. Michael Greger (01:21), Eric Berg (36:26), and Dr. Paul Saladino (55:18). We give reference to some specific examples. Show notes available at sigmanutrition.com/episode401/ If you wish to support the podcast you can do so via patreon.com/sigmanutrition/

Links: Go to episode page Receive Danny's free emails Subscribe to Sigma Nutrition Premium About This Episode: To celebrate our 400th episode, we take a look at two "quacks" who spread misinformation; Dr. Aseem Malhotra and Dr. James DiNicolantonio. We give reference to some specific examples.

James Betts is Professor of Metabolic Physiology at the University of Bath, where he is Co-Director of the Centre for Nutrition, Exercise & Metabolism. His research employs randomised controlled trials to study the effects of nutrition on metabolic regulation. His group recently published a trial aiming to separate out the effects of fasting from those of calorie restriction. Show notes at sigmanutrition.com/episode399/

Carole Hooven, PhD, is lecturer and codirector of undergraduate studies in the Department of Human Evolutionary Biology at Harvard University. She earned her PhD at Harvard, studying behavioral endocrinology and evolution of sex differences in humans (physiology, behavior and cognition). She has recently written a book on how testosterone influences behaviour and explains many sex differences. The book is titled 'T: The Story of Testosterone, the Hormone that Dominates and Divides Us'. Show notes available at sigmanutrition.com/episode398/

In this episode Danny & Alan discuss the impacts of nitrates and nitrites on health. They look at the beneficial impacts of dietary nitrate, as well as issues around nitrites in processed meat. Show notes available at sigmanutrition.com/episode397/

Dr. Leigh Frame, PhD is Director of Integrative Medicine at George Washington School of Medicine and Health Sciences in Washington DC. Dr. Frame received her PhD in Human Nutrition, as well as a Master of Health Science degree in Molecular Microbiology and Immunology, from the Johns Hopkins Bloomberg School of Public Health. In this episode we discuss a range of topics including: the role of placebo groups and the different types we see in nutrient supplementation trials, potential ethical issues, and the development of research ethics. Show notes available at sigmanutrition.com/epsiode396/

" data-userid="424351203778215936" data-orgid= "425311536639447040">Professor le Roux is an expert in metabolic medicine and is currently a Professor of Experimental Pathology, University College Dublin. He is recognised as a world leader in metabolism and obesity. " data-userid="424351203778215936" data-orgid= "425311536639447040">Professor le Roux's clinical focus is in the management of Type 2 diabetes, pre-diabetes, obesity, cardiovascular risk and other metabolic disorders. Professor Carel le Roux has been published extensively and currently holds a number of editorial roles for journals in his field including, Clinical Obesity and Surgery for Obesity and Related Diseases. " data-userid="424351203778215936" data-orgid= "425311536639447040">Show notes are available at: sigmanutrition.com/episode395

Gar Benn is the Head of Coaching at Sigma Nutrition, where he works with nutrition coaching clients and oversees the coaching services. He is the owner of CityGym Limerick, a powerlifting-centric gym in Ireland. And he is also the co-founder of the European Powerlifting Confernce and Titan Ireland. Gar is a qualifed nutrition coach and has completed courses in Motivational Interviewing and Acceptance and Commitment Therapy (ACT). Show notes at sigmanutrition.com/episode394/

Click here to subscribe to Sigma Nutrition Premium Vitamin D status is linked to a variety of health outcomes, and avoiding or correcting deficiency is important. However, does supplementing with vitamin D actually benefit most people? Is there evidence for supplementation improving health outcomes like mortality, cancer risk, depression or other outcomes? In this episode Danny and Alan look at intervention trials of vitamin D supplementation. Show notes available at: https://sigmanutrition.com/episode393/ Click here to subscribe to Sigma Nutrition Premium

Dr. Clare Pettinger is a Registered Dietitian, Public Health Nutritionist and experienced educator. Dr. Pettinger publishes research in the public health nutrition field, and lectures at the Universtity of Plymouth, UK. Dr. Pettinger is actively engaged in community-focussed research around food systems, poverty and social justice. She is an enthusiastic 'sustainability advocate' involved in promoting environmentally sustainable diets for nutrition professionals and Allied Health Professioinals. Show notes available at sigmanutrition.com/episode392

In this episode Danny and Alan discuss the three primary models used to explain body mass regulation: 1) Set Point Model, 2) Settling Point Model, 3) Dual Intervention Model. They discuss the role of feedback systems, environment, behaviour, as well as discussing both the "thrifty gene hypothesis" and John Speakman's "drifty gene hypothesis".

Gil Carvalho, MD PhD is a medical doctor, research scientist, science communicator. Dr. Carvalho trained as a medical doctor in the University of Lisbon, in his native Portugal, and later obtained a PhD in Biology from Caltech (California Institute of Technology). He has published peer-reviewed medical research spanning the fields of genetics, molecular biology, nutrition, behaviour, aging and neuroscience. In this episode we discuss: Dairy: is it over-emphasized in the Dietary Guidelines for Americans? Dairy tolerance Critical importance of substitution effects Differences between difference types of dairy on health Claims by some WFPB advocates that olive oil can negatively impact endothethial function Distinguishing between acute and chronic effects Gil's work with Antonio Damasio on feelings Show notes: https://sigmanutrition.com/episode190

Renee McGregor is a leading sports dietitian, specialising in Eating Disorders, REDs, The Female Athlete, athlete health and performance. She is regularly asked to work directly with high performing and professional athletes that have developed a dysfunctional relationship with food that is impacting their performance, health and career. Her practice and knowledge is supported by extensive experience of working in both clinical and performance nutrition, including, Olympic, Paralympic and Commonwealth teams. She is the co-founder and director of #TRAINBRAVE a campaign raising the awareness of eating disorders in sport; providing resources and practical strategies to reduce the prevalence. She is on the REDS advisory board for BASES (The British Association of Sport and Exercise Science) and sits on the International Task Force for Orthorexia. Find the show notes at sigmanutrition.com/episode389

Danny & Alan discuss the current evidence on the health consequences and societal consequences of weight stigma and weigh bias. This includes implicit bias, explicit bias, and internalization of bias. What evidence do we currently have? And what questions remain unanswered? Segments: Today's Topic in Focus [03:39] Listener Questions [59:48] Quack Asylum [68:55] Random Recommendations [72:07] You can find the show notes to this episode at sigmanutrition.com/episode388 If you wish to support the podcast you can do so on Patreon at patreon.com/sigmanutrition or directly via the site at sigmanutrition.com/donate

In this episode Danny and Alan discuss the relationship between shift work and health. Why does shift work have negative health impacts? How can one mitigate circadian misalignment? How does shift work impact nutrient metabolism? What nutrition, sleep and lifestyle strategies can help shift workers? Show notes at: sigmanutrition.com/episode387

Dr. Tobias is a nutrition and obesity epidemiologist at the Brigham and Women's Hospital and Harvard Medical School in Boston, MA. She received doctoral and postdoctoral training from the Harvard TH Chan School of Public Health, Boston, MA, under mentor Dr. Frank B. Hu. Dr. Tobias is co-Instructor of Nutrition Epidemiology with Dr. Walter Willett and faculty member at the Harvard TH Chan School of Public Health. Her epidemiologic research focuses on identifying lifestyle risk factors and underlying mechanisms related to obesity and its major chronic diseases, including type 2 diabetes and cancer. Dr. Tobias is currently the Academic Editor for the American Journal of Clinical Nutrition. Show notes at sigmanutrition.com/episode386

In this episode we explore the causes of insulin resistance, and the dietary modifications that may help those with insulin resistance. We discuss how insulin resistance is a complex metabolic disorder, that goes beyond one single pathway or cause. There is also a discussion on the mechanisms of insulin resistance pathogenesis. Specifically, we talk about the accumulation of ectopic fat. Ectopic fat is the storage of triglycerides in tissues other than fat tissue, such as the liver, skeletal muscle, heart, and pancreas. There is also an overview of the Twin-Cycle Hypothesis, which was discussed in more detail in a previous episode with Prof. Roy Taylor. In addition, we give special mention to liver fat accumulation and the relationship between insulin resistance and non-alcoholic fatty liver disease (NAFLD). Then various diet interventions are assessed for their potential usefulness to those with insulin resistnace. This includes different diet types (e.g. whole-food plant-based diet, low-carbohydrate ketogenic diet, etc.), role of macronutrients, pre-loading studies, and the role of meal timing and circadian effects. Find the show notes at https://sigmanutrition.com/episode385

In this episode Greg Nuckols and Mike Zourdos breakdown two research papers related to the interference effect and concurrent training. Greg and Mike (along with Eric Helms and Eric Trexler) produce the MASS research review, which breaks down the latest research studies relevant to those interested in strength training, strength sports, and bodybuilding. From April 27th to May 4th you can get a significant discount on a MASS subscription by visiting sigmanutrition.com/mass-sale/

In this episode Danny and Alan discuss irritable bowel syndome and the evidence related to dietary interventions. They discuss diagnosis of the condition, various sub-types, potential mechanisms, the gut-brain axis, first line treatments, impact of fibre, and evidence on the low FODMAP diet. Today's Topic in Focus: IBS & Diet [06:20] "I Have a Question!" [74:47] Quack Asylum [79:30] Random Recommendations [86:49] Show notes available at sigmanutrition.com/episode383

Andy Morgan is the founder of RippedBody.com and an online coach. He co-authored the Muscle & Strength Pyramids books along with Dr. Eric Helms and Andrea Valdez. He has published a host of excellent nutrition and training resources in the form of ebooks, articles and podcasts, which can be found on the Ripped Body website. He recently released the third edition of the Diet Adjustments Manual. You can find the show notes to this episode at: sigmanutrition.com/episode382

Prof. Chris Packard holds an Honorary Professorship of Vascular Biochemistry at the University of Glasgow. Over his career, Professor Packard has focussed on two aspects of atherosclerosis research, lipoprotein metabolism and how it is affected by diets and drugs, and large-scale clinical trials of lipid lowering agents. He is acknowledged as one of the leading researchers in the world in this field. Show notes available at sigmanutrition.com/episode381

Prof. Barry Popkin is the W.R. Kenan Jr. Distinguished Professor of Nutrition at the University of North Carolina at Chapel Hill. He is a nutrition and obesity researcher at the Carolina Population Center and is the director of the Interdisciplinary Center for Obesity at UNC. He developed the concept of the Nutrition Transition, the study of the dynamic shifts in dietary intake and physical activity patterns and trends around obesity and other nutrition-related noncommunicable diseases (NCD). Prof. Popkin is involved now in work on program and policy design at the national level to improve the average diet at the population level. He has published more than 545 journal articles, and is one of the most cited nutrition scholars in the world, with more than 90,000 citations. Show notes available at sigmanutrition.com/episode380

Danny and Alan are joined by Dr. Spencer Nadolsky. Dr. Nadolsky is a board-certified obesity specialist, lipidologist, and family physician. In this episode we discuss the strengths and limitations of BMI, adipose tissue type and relevance to risk, hypertrophic vs. hyperplastic adipocytes, 'Metabolically Healthy Obesity', and weight stigma. Show notes available at sigmanutrition.com/episode379

In this episode Danny and Alan discuss some critical aspects to understand about nutritional epidemiology in order to evaluate diet-disease relationships appropriately. Of particular focus in this episode is the unique exposure of interest in nutrition studies, why its crucial to understand temporal relationships and how to think about relative risk and absolute risk. The guys finish by explaining how one can include these findings into an understanding of an overall body of evidence. Show notes: sigmanutrition.com/episode378

Herman Pontzer, PhD is an Associate Professor of Evolutionary Anthropology at Duke University and Associate Research Professor of Global Health at the Duke Global Health Institute. He is an internationally recognized researcher in human energetics and evolution. Over two decades of research in the field and laboratory, Dr. Pontzer has conducted pathbreaking studies across a range of settings, including fieldwork with Hadza hunter-gatherers in northern Tanzania, fieldwork on chimpanzee ecology in the rainforests of Uganda, and metabolic measurements of great apes in zoos and sanctuaries around the globe. Find the show notes to this episode at sigmanutrition.com/episode377

Dr. Kevin Hall, PhD is Senior Chief of the Integrative Physiology Section of the Laboratory of Biological Modeling at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). His laboratory investigates how metabolism and the brain adapt in response to a variety of interventions to diet and physical activity. They carry out studies to better understand the complex mechanisms regulating macronutrient metabolism, body composition, and energy expenditure. Recently Dr. Hall was lead author on a study titled 'Effect of a plant-based, low-fat diet versus an animal-based, ketogenic diet on ad libitum energy intake', which was published in Nature Medicine in early 2021. [Disclaimer: By participating in this podcast, the U.S. Government, represented by the National Institutes of Health does not directly or indirectly endorse any product or service provided, or to be provided, by Sigma Nutrition.] Link to show notes: sigmanutrition.com/episode376

In this episode Danny and Alan discuss the current evidence base related to sodium intake and health, most notably cardiovascular disease. The episode walks through understanding diet-disease relationships, the epidemiology of sodium and health outcomes, the reasons for conflicting conlusions, sodium measurements in research, intervention trials, and more. Importantly, the claim that the sodium-CVD risk relationship exhibits a "J-shaped curve" (i.e. risk is low at moderate intakes and higher at both low and high intakes) is dissected, with recommendations given on how to reconcile all the available evidence.

In this episode Danny becomes the interviewee, as he is interviewed by sports dietitian and owner of The Fight Dietitian, Jordan Sullivan RD. Jordan oversees the diet of several UFC athletes, including champions Israel Adesanya and Alexander Volkanovski. Danny and Jordan have an in-depth chat about all aspects of nutrition and weight cutting for combat sport athletes, including the concept of the "52 week fight camp" and Danny's five-phase model of combat sport nutrition. This discussion first appeared on the Fight Science Podcast. Thanks to Jordan Sullivan for allowing its reproduction here. Show notes: sigmanutrition.com/episode374 Weight Cutting System: sigmanutrition.com/weightcut

In this episode Danny and Alan discuss the health impacts of alcohol and take a look at the research to answer whether alcohol should be viewed as having a J-shaped curve of risk or zero alcohol being better than any amount. Segments: [03:40] Today's Topic in Focus [53:45] "I Have a Question!" [62:14 ]Random Recommendations Show notes available at sigmanutrition.com/episode373

Dr. Mike Israetel​ is the cofounder of Renaissance Periodization, where he produces content related to training and dieting for hypertrophy, strength and bodybuidling. Dr. Israetel is also currently a professor in the strength and hypertrophy masters program at Lehman College. Mike is himself a competitive bodybuilder and professional Brazilian Jiu Jitsu grappler. Show notes available at sigmanutrition.com/episode372

In this episode Danny and Alan discuss the debate over the impact of dietary cholesterol on LDL-C levels and heart disease risk. Are eggs & cholesterol-rich foods a problem? Let's dive into the research to find out! Today's Topic in Focus: [00:51] "I Have a Question!" [62:32] Quack Asylum [72:55] Random Recommendations [75:28] Show notes: https://sigmanutrition.com/episode371

Dr. Jake Mey is a registered dietitan and a human nutrition researcher. He is a Postdoctoral Research Fellow at the Pennington Biomedical Research Center. His work focuses on diet, muscle & metabolism. Dr. Mey has a PhD in human nutrition and kinesology. Show notes: sigmanutrition.com/episode370

Professor Jason Gill is a Professor of Cardiometabolic Health in the Institute of Cardiovascular and Medical Sciences at the University of Glasgow. He leads an active multi-disciplinary research group investigating the effects of exercise and diet on the prevention and management of vascular and metabolic diseases from the molecular to the whole-body level. He is a past Chair of the British Association of Sport and Exercise Sciences (BASES) Division of Physical Activity for Health and a member of the development groups for the Scottish Intercollegiate Guidelines Network (SIGN) guidelines for the prevention and treatment of obesity and for prevention of cardiovascular disease. In this episode we discuss: Strength and chronic disease risk Discrepancy between self-report and objective measurements of physical activity Regression dilution bias: If you measure something poorly you diminish the apparent association with the outcome The EuroFIT randomized controlled trial The amount of exercise needed to get to a point of low absolute risk of cardiometabolic disease is more for high-risk populations vs. low-risk populations Why if you have a higher genetic risk for obesity, then lifestyle matters more, not less Should there be differential guidelines for activity based on race/ethnicity? Interaction between degree of social deprivation, lifestyle and health outcomes Why reducing sitting time may not be a useful target LINK: sigmanutrition.com/episode369

Shannon Beer is a nutritionist, working with people via online coaching and mentoring, with the goal of helping people improve their health through facilitating lasting behaviour change. In collaboration with Dr. Gabrielle Fundaro, she has developed a coaching framework that applies motivational interviewing, cognitive behavioral coaching, and acceptance and commitment therapy-aligned processes in a client-centered alliance toward their own values-based goals. This 'Comprehensive Coaching' model facilitates long-term behavior change and flourishing health in clients. Show notes: sigmanutrition.com/episode368

Dr. Gabrielle Fundaro is a nutrition/health coach who focuses on facilitating behavior change, embodying a positive relationship with food, cultivating positive body image, and improving sport performance. Dr. Fundaro is a former Assistant Professor of Exercise Science at Georgia Gwinnett College and holds a PhD in Human Nutrition and Exercise. She is currently a board member of both the Nutrition Coaching Global Mastermind (NCGM) and the Sports Nutrition Association (SNA). In collaboration with Shannon Beer, she has developed a coaching framework that applies motivational interviewing, cognitive behavioral coaching, and acceptance and commitment therapy-aligned processes in a client-centered alliance toward their own values-based goals. This 'Comprehensive Coaching' model facilitates long-term behavior change and flourishing health in clients. LINK: sigmanutrition.com/episode367