Neurology® Podcast

Dr. Tesha Monteith talks with Dr. Wouter Schievink about what spontaneous intracranial hypotension is and why it's commonly misdiagnosed. Visit NPUb.org/Podcast for additional podcasts and associated article links.

Dr. Jason Crowell talks with Dr. Frederic Schaper about lesion-related epilepsy mapping to specific brain networks. Read the related article in JAMA Neurology. Visit NPUb.org/Podcast for additional podcasts and associated article links.

Dr. Gordon Smith talks with Dr. Ajay Sampat about his journey of being a neurologist and getting diagnosed with ALS at 36. Visit NPUb.org/Podcast for additional podcasts and associated article links.

In the third episode of a four-part series on autoimmune encephalitis, Dr. Justin Abbatemarco talks with Drs. Eoin Flanagan and Grace Gombolay about a practical approach to testing for auto antibodies and autoimmune encephalitis. Visit NPUb.org/Podcast for additional podcasts and associated article links.

In the second episode of a four-part series on autoimmune encephalitis, Dr. Justin Abbatemarco talks with Drs. Sarosh Irani and John Soltys about a practical approach to testing for auto antibodies and autoimmune encephalitis. Visit NPUb.org/Podcast for additional podcasts and associated article links.

In the first episode of a four-part series on autoimmune encephalitis, Dr. Justin Abbatemarco talks with Dr. Josep Dalmau about relevant updates on autoimmune encephalitis, ongoing/upcoming clinical trials, and so much more. Visit NPUb.org/Podcast for additional podcasts and associated article links.

In this first episode of our three-part series, Prof. Jon Stone talks with Drs. Selma Aybek, David Perez, and Sarah Lidstone about FND diagnosis and exploring new phenotypes. Related Links: FND Society at fndsociety.org FND guide for patients at neurosymptoms.org FND Hope at fndhope.org Visit NPUb.org/Podcast for associated article links. This episode was sponsored by the ExTINGUISH Trial for NMDAR Encephalitis: Call 844-4BRAIN5 to refer patients.

The August 2023 replay of past episodes showcases four interviews on functional neurologic disorders with Prof. Jon Stone. The episode begins with an interview by Prof. Jon Stone and Dr. Tamara Pringsheim with Wall Street Journal columnist Julie Jargon about the increased incidence of teen girls presenting with physical tics. The Recall episode continues with an interview with Drs. Tamara Pringsheim and Davide Martino about the latest updates on those functional tics and new diagnostic criteria. The third interview is with Dr. Tjerk Lagrand about how the diagnosis of functional seizures affects health care costs. The August Recall concludes with Dr. Mahinda Yogarajah about the importance of diagnosing and not misdiagnosing functional neurologic disorders. Related Podcast Links: Tik Tok Tics - https://directory.libsyn.com/episode/index/id/21928034 Functional Tic Update - https://directory.libsyn.com/episode/index/id/26601993 Health Care Utilization in FND - https://directory.libsyn.com/episode/index/id/25624821 Economic Cost of Functional Neurologic Disorders - https://directory.libsyn.com/episode/index/id/27225606 Related Article Links: How Teens Recovered from the 'Tik Tok Tics' - https://www.nytimes.com/2023/02/13/health/tiktok-tics-gender-tourettes.html Economic Cost of Functional Neurologic Disorders: A Systematic Review: https://n.neurology.org/content/early/2023/06/20/WNL.0000000000207388

Dr. Stacey Clardy talks with Dr. Natalia Rost about her experience speaking before the House of Representatives on the approval of lecanemab for the treatment of early Alzheimer disease. Visit NPUb.org/Podcast for associated article links. This episode was sponsored by the ExTINGUISH Trial for NMDAR Encephalitis: Call 844-4BRAIN5 to refer patients.

Dr. Justin Abbatemarco talks with Dr. Amel Karaa about the use of elamipretide in participants with genetically confirmed primary mitochondrial myopathies. Read the related article in Neurology. Visit NPUb.org/Podcast for associated article links.

Dr. Gordon Smith talks with Dr. Hoda Abdel-Hamid about the recent FDA approval for the first ever gene therapy for Duchenne muscular dystrophy. Visit NPUb.org/Podcast for associated article links.

Dr. Kathryn Nevel talks with Dr. Ingo Mellinghoff about how vorasidenib improved progression-free survival in patients with Isocitrate dehydrogenase (IDH)–mutant grade 2 gliomas. Read the related article in The New England Journal of Medicine. Visit NPUb.org/Podcast for associated article links.

Dr. Jason Crowell talks with Prof. Jacob Elberg to provide neurologists with an insight into what goes on behind the scenes for patient-assistance programs. Read the related article in The New England Journal of Medicine. Visit NPUb.org/Podcast for associated article links.

Dr. Dan Ackerman talks with Dr. Thanh Nguyen about whether dual antiplatelet therapy is noninferior to intravenous thrombolysis among patients with minor nondisabling acute ischemic stroke. Read the related article in JAMA. Visit NPUb.org/Podcast for associated article links. This episode was sponsored by the ExTINGUISH Trial for NMDAR Encephalitis: Call 844-4BRAIN5 to refer patients.

Dr. Stacey Clardy talks with Dr. Jonathan Graff-Radford about everything we need to know about corticobasal syndrome. Read the related article in Neurology. Visit NPUb.org/Podcast for associated article links. This episode was sponsored by the ExTINGUISH Trial for NMDAR Encephalitis: Call 844-4BRAIN5 to refer patients.

Dr. Gordon Smith talks with Drs. Ruben P.A. van Eijk and Jordi van Unnik about the planning of interim analyses for clinical trials in ALS to maximize patient safety and minimize exposure to ineffective or harmful drugs. Read the related article in Neurology. Visit NPUb.org/Podcast for associated article links.

Dr. Justin Abbatemarco talks with Dr. Bart Jacobs about cerebrospinal fluid findings in relation to clinical and electrodiagnostic subtypes, severity, and outcome of Guillain-Barré syndrome. Read the related article in Neurology. Visit NPUb.org/Podcast for associated article links.

The July 2023 replay of past episodes showcases five interviews on social determinants of health in neurology. The episode begins with an interview with Dr. Heather Leeper on the links between pain and depression with unemployment due to CNS cancer. The episode continues with an interview with Dr. Wyatt Bensken on racial and ethnic difference in antiseizure medication prescription. The next interview is with Dr. Scott Mendelson on race-ethnic disparities in stroke thrombolysis. The fourth interview is with Dr. Vikas Kotagal on neighborhood socioeconomic factors in people with various movement disorders. The final episode is with Dr. Daniel Di Luca on racial and ethnic differences in quality of life among people with Parkinson's disease. Related Podcast Links: Links Between Pain & Depression with Unemployment Due to CNS Cancer: https://directory.libsyn.com/episode/index/id/26356875 Racial and Ethnic Differences in Antiseizure Medications Among People with Epilepsy on Medicaid: https://directory.libsyn.com/episode/index/id/25916646 Race-Ethnic Disparities in Stroke Thrombolysis: https://directory.libsyn.com/episode/index/id/23377391 Social Determinants of Health in Patients with Movement Disorders: https://directory.libsyn.com/episode/index/id/26531040 Racial and Ethnic Differences in Quality of Life in Parkinson Disease: https://directory.libsyn.com/episode/index/id/27196008 Related Article Links: Association of Employment Status With Symptom Burden and Health-Related Quality of Life in People Living With Primary CNS Tumors: https://n.neurology.org/content/100/16/e1723 Racial and Ethnic Differences in Antiseizure Medications Among People With Epilepsy on Medicaid: A Case of Potential Inequities: https://cp.neurology.org/content/13/1/e200101 Race-Ethnic Disparities in Rates of Declination of Thrombolysis for Stroke: https://n.neurology.org/content/98/16/e1596 Neighborhood Social Determinants of Health in Patients Seen in Neurology Movement Disorders Clinics: https://cp.neurology.org/content/13/2/e200142 Racial and Ethnic Differences in Health-Related Quality of Life for Individuals With Parkinson Disease Across Centers of Excellence: https://n.neurology.org/content/100/21/e2170 Visit NPUb.org/Podcast for associated article links

Dr. Tesha Monteith talks with Dr. Andrew Charles about new updates in the field of migraine following the American Headache Society conference in honor of National Migraine and Headache Awareness Month. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Dr. Andy Southerland talks with Dr. Seemant Chaturvedi about this year's European Stroke Organization Conference and pivotal trials that were presented during the conference. Read the related content on the ESOC Plenary Highlights page. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Prof. Jon Stone talks with Dr. Mahinda Yogarajah about the importance of diagnosing and not misdiagnosing functional neurologic disorders. Read the related article in Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Dr. Daniel Garbin Di Luca about racial and ethnic differences in health-related quality of life for individuals with Parkinson disease. Read the related article in Neurology. For links to articles and previous podcast episodes, please visit NPUb.org/Podcast. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Special Episode - Neurology Podcast: Dr. Farrah Mateen talked with Dr. Martin A. Samuels for the living legends series back in 2013. Listen to this previously posted episode in memory of Dr. Samuels. For links to articles and previous podcast episodes, please visit NPUb.org/Podcast. Find the link to the original episode here: https://directory.libsyn.com/episode/index/id/8128592

Dr. Tesha Monteith talks with Dr. Messoud Ashina about a ten-step approach for the diagnosis and management of migraines in various patient populations. Read the related article in Nature Review Neurology. For links to articles and previous podcast episodes, please visit NPUb.org/Podcast. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Dr. Derek Stitt talks with Dr. Karin Diserens about subtle signs and motor behavior to unveil awareness in unresponsive brain-impaired individuals. Read the related article in Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org

Dr. Gregg Day talks with Prof. Ronald Postuma about the conflicting evidence regarding the association between seasonal changes and daylight-saving time and sleep disorders. Read the related article in Neurology. For links to articles and previous podcast episodes, please visit NPUb.org/Podcast. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Dr. Derek Stitt talks with Dr. Andrew Callen about the relationship between bern score, spinal elastance, and opening pressure in patients with spontaneous intracranial hypotension. Read the related article in Neurology. Disclosures can be found at Neurology.org. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

The June 2023 replay of past episodes showcases a selection of interviews regarding the biomarker discovery in Parkinson disease. This episode begins with an overview of the latest in Parkinson's research, including biomarker development with Dr. Bas Bloom. The episode continues with an interview with Dr. Lucilla Parnetti about the clinical application of α-synuclein seed amplification, leading into an interview with Prof. Andrew Siderowf about seed amplification in PD in the PPMI cohort. The June Neurology Recall concludes with an interview with Dr. Christopher Gibbons on skin α-synuclein in MSA and PD. Related Podcast Links: Biomarker and Treatment Development in Movement Disorders: https://directory.libsyn.com/episode/index/id/26775207 Alpha-synuclein Amplification for Disease Diagnosis: https://directory.libsyn.com/episode/index/id/23923047 α-Synuclein Seed Amplification in a Large Parkinson Cohort: https://directory.libsyn.com/episode/index/id/26961315 Skin α-Synuclein In MSA and PD: https://directory.libsyn.com/episode/index/id/26499948 Related Article Links: Research in Movement Disorders in 2022: A New Era of Biomarker and Treatment Development: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(22)00494-X/fulltex Synuclein Seed Amplification Assays for Diagnosing Synucleinopathies: The Way Forward: https://n.neurology.org/content/99/5/195 Assessment of Heterogeneity Among Participants in the Parkinson's Progression Markers Initiative Cohort Using _-Synuclein Seed Amplification: A Cross-Sectional Study: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00109-6/fulltext Cutaneous _-Synuclein Signatures in Patients With Multiple System Atrophy and Parkinson Disease: https://n.neurology.org/content/100/15/e1529 Disclosures can be found at Neurology.org

Dr. Alison Christy talks with Dr. Tatjana Bremova-Ertl about the use of N-acetyl-L-leucine in pediatric and adult patients with GM2 gangliosidoses. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Prof. Andrew Siderowf about the assessment of heterogeneity among participants in the Parkinson progression markers initiative cohort using α-synuclein seed amplification. Read the related article in The Lancet Neurology. Disclosures can be found at Neurology.org.

Dr. Stacey Clardy talks with Dr. Nico Dosenbach about topographic brain organization and redrawing the homunculus. Read the related article in Nature. Disclosures can be found at Neurology.org.

Dr. Farrah Mateen talks with Dr. Deanna Saylor about proposed competencies that can serve as a basis for global neurology training programs. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Gordon Smith talks with Dr. Suma Babu about a newly approved treatment for ALS that is associated with a mutation in the superoxide dismutase 1 (SOD1) gene. Read the related article on the FDA website. Disclosures can be found at Neurology.org

Dr. Jason Crowell talks with Dr. Farrah Mateen about clinical information that neurologists and other clinicians can use to treat people who are forcibly displaced. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Prof. Bastiaan Bloem about the latest developments in biomarkers and treatments for movement disorders, which have been described in numerous research papers from 2022. Read the related article in The Lancet. Disclosures can be found at Neurology.org.

Dr. Tesha Monteith talks with Dr. Mark Burish about circadian-targeted research into cluster headaches and migraines. Read the related article in Neurology. Disclosures can be found at Neurology.org

Dr. Jason Crowell talks with Dr. Sophie Cho, Program Director in the Division of Clinical Research at NINDS, about the state of Parkinson disease research. For links to previous podcast episodes, please visit NPUb.org/Podcast. Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Dr. Raúl Martínez-Fernández about the long-term outcome of unilateral FUS-STN treatment for Parkinson disease. Read the related article in Neurology. Disclosures can be found at Neurology.org.

The May 2023 Neurology Recall showcases five dynamic interviews around multiple sclerosis. This episode features conversations with Dr. Bruce Bebo on cost burden of MS in the United States; followed by an interview with Dr. Christian Cordano on retinal and cortical atrophy in MS; leading into an interview with Dr. Alberto Ascherio on the association of EBV and MS. May's Neurology Recall concludes with conversations with Dr. Tyler Ticomb on the efficacy of diet on fatigue and quality of life in MS and an interview with Dr. Matilde Inglese on hematopoietic stem cell transplant in secondary progressive MS. Related Podcast Links: Cost Burden of MS in the US: https://directory.libsyn.com/episode/index/id/22979720 Retinal and Cortical Atrophy in MS: https://directory.libsyn.com/episode/index/id/24714711 Association of EBV and Multiple Sclerosis https://directory.libsyn.com/episode/index/id/22394066 Efficacy of Diet on Fatigue and Quality of Life in Multiple Sclerosis: https://directory.libsyn.com/episode/index/id/25428246 Hematopoietic Stem Cell Transplant in Secondary Progressive MS: https://directory.libsyn.com/episode/index/id/26217204 Related Article Links: The Economic Burden of Multiple Sclerosis in the United States: Estimate of Direct and Indirect Costs: https://n.neurology.org/content/98/18/e1810 Differences in Age-related Retinal and Cortical Atrophy Rates in Multiple Sclerosis: https://n.neurology.org/content/99/15/e1685 Efficacy of Diet on Fatigue and Quality of Life in Multiple Sclerosis: A Systematic Review and Network Meta-analysis of Randomized Trials: https://n.neurology.org/content/100/4/e357 Efficacy of Diet on Fatigue and Quality of Life in Multiple Sclerosis: A Systematic Review and Network Meta-analysis of Randomized Trials: https://n.neurology.org/content/100/4/e357 Disclosures can be found at Neurology.org

Dr. Andrew Southerland talks with Dr. Alejandro Rabinstein and Hassan Kobeissi about comparing outcomes between CTP and NCCT for EVT selection in the late therapeutic window. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Matthew Harms talks with Dr. Emily Plowman about the effects of inspiratory and expiratory respiratory strength training (RST) programs in individuals with ALS. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Prof. Jon Stone speaks with Drs. Tamara Pringsheim and Davide Martino about the latest updates on functional tic-like behaviors and new diagnostic criteria. For more information on this topic, check out the previous conversation from January 2022 with Prof. Jon Stone and Dr. Tamara Pringsheim. Read the related article in The New York Times. Read the other related articles in the European Journal of Neurology by Dr. Martino and Dr. Pringsheim. Disclosures can be found at Neurology.org.

Dr. Tesha Monteith talks with Dr. Alexandra Jean Sinclair about disease course and long-term outcomes in pregnant women with idiopathic intracranial hypertension. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Dr. Vikas Kotagal about how neighborhood socioeconomic factors vary among individuals with different types of clinical movement disorders. Read the related article in Neurology: Clinical Practice. Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Dr. Christopher Gibbons about the need for accurate diagnostic and prognostic biomarkers for MSA and its differentiation from other synucleinopathies. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Dr. David Lynch about the use of omaveloxolone for patients with friedreich ataxia. Read the related article in Annuals of Neurology. Disclosures can be found at Neurology.org.

Dr. Tesha Monteith talks with Dr. Martin Underwood about supportive self-management programs for people living with chronic migraines or chronic tension-type headaches with episodic migraines. Read the related article in Neurology. Disclosures can be found at Neurology.org

The April 2023 replay of past episodes showcases our November 2022 headache series hosted by Dr. Tesha Monteith. The first episode features a conversation with Dr. Peter Goadsby about the value offered by headache classifications, followed by an interview with Drs. Simona Sacco and Jessica Ailani about an update on migraine guidelines. Next in the episode, Dr. Lars Edvinsson discusses CGRP and the role of sex hormones. The April recall closes out with an interview with Dr. Rebecca Burch about hot topics in headache medicine. Related Podcast Links: November Headache Series: Increasing the Value of Neurology Through Headache Classifications: http://directory.libsyn.com/episode/index/id/24894771 November Headache Series: Update on Migraine Guidelines: https://directory.libsyn.com/episode/index/id/25083906 November Headache Series: CGRP and Role of Sex Hormones: https://directory.libsyn.com/episode/index/id/24967986 November Headache Series: Hot Topics in Headache Medicine: https://directory.libsyn.com/episode/index/id/25042293 Disclosures can be found at Neurology.org

This episode features Dr. Stacey Clardy in conversation with the 2023 Ted Burns Humanism in Neurology Award winner, Dr. Deanna Saylor. Disclosures can be found at Neurology.org.

Dr. Stacey Clardy and Dr. Heather Leeper discuss the social ramifications of a neurological diagnosis and the importance of palliative care. They emphasize the role of social workers in these difficult conversations and highlight the valuable resources they can connect patients to. Read the related article in Neurology. Disclosures can be found at Neurology.org.