Neurology® Podcast

Dr. Halley Alexander talks with Dr. Valérie van Hezik-Wester about whether people living with severe medically refractory epilepsy (PSRE) benefit from a seizure dog. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Halley Alexander talks with Dr. Genevieve Rayner and Eliza Honybun about the relationship between prenatal antiseizure medication exposure and adverse postnatal neurodevelopmental outcomes. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Dr. Carles Gaig about developing a composite score to assess the severity of the multiple symptoms present in anti-IgLON5 disease. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Stacey Clardy talks with Aaron Baldwin about how access to genetic testing may vary based on various factors such as race, ethnicity, sex, socioeconomic status, and insurance status. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Deanna Saylor talks with Drs. Gretchen Birbeck and Melody Asukile about ways to improve global collaboration among neurologists. Read the related article in JAMA Neurology. Disclosures can be found at Neurology.org.

Dr. Howard Goodkin talks with Dr. Fred Lado about the National Association of Epilepsy Centers (NAEC) updated guidelines for specialized epilepsy centers. Read the related article in Neurology. Disclosures can be found at Neurology.org.

The March 2024 recall includes three episodes taken from the 2023 November Headache Series. In part two of this two-part recall, Dr. Tesha Monteith begins with a discussion with Dr. Messoud Ashina on the mechanisms of migraine. The episode continues with Dr. Peter Goadsby talking about updates on migraine treatments and CGRP inhibitors. Finally, the episode concludes with an interview with Dr. Stewart Tepper discussing rapid developments in neuromodulation. Related Podcast Links: https://directory.libsyn.com/episode/index/id/28721028 https://directory.libsyn.com/episode/index/id/28812568 https://directory.libsyn.com/episode/index/id/28868248 Disclosures can be found at Neurology.org

Dr. Tesha Monteith talks with Dr. Robert Evan Shapiro about the impact that migraine has on quality of life and the frequency of migraine-related stigma. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Shuvro Roy talks with Dr. Riley Bove about managing patients with multiple sclerosis as they navigate family planning and pregnancy. Read the related article in Neurology: Clinical Practice. Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Dr. Subhojit Roy about a platform for investigating the role of serine-129 in synucleinopathies, with implications for drug development. Read the related article in the Neuron. Disclosures can be found at Neurology.org.

Dr. Gregg Day talks with Drs. Thomas J. Montine and Brenna Cholerton about whether the association between neuropathologic burden and dementia in these older groups differs substantially from those seen in younger-old adults. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Derek Stitt talks with Dr. David T. Plante about the Wisconsin Sleep Cohort study to estimate the prevalence of idiopathic hypersomnia. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Justin Abbatemarco talks with Prof. Xavier Ayrignac about the importance of considering alternative diagnoses for CTLA4 deficiencies. Read the related article in Neurology.

Dr. Stacey Clardy talks with Bob Herman about a class action lawsuit that was filed against UnitedHealth Group and its subsidiary, NaviHealth, for using a computer algorithm to "systematically deny claims" of Medicare beneficiaries struggling to recover from debilitating illnesses in nursing homes. Read the related article in STAT News. Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Dr. Jason Margolesky about the frequency of blepharoclonus in Parkinson disease and atypical Parkinsonian disorders to explore whether this clinical phenomenology may be useful in the evaluation and diagnosis of patients with Parkinsonism. Read the related article in Neurology: Clinical Practice. Disclosures can be found at Neurology.org.

The February 2024 recall includes three episodes taken from the 2023 November Headache Series and will be part 1 of a two-part Recall series. In the first part of this two-part recall, Dr. Tesha Monteith begins with a discussion on the highlights of the 2023 International Headache Conference with Drs. Hayrunnisa Bolay, KC Brennan, and Gianluca Coppola. The episode continues with Dr. Stephanie Nahas discussing commonly missed and lesser-known primary headache disorders. Finally, the episode concludes with an interview with Drs. Deb Friedman and Kathleen Digre, who talk about the diagnosis and management of IIH and other CSF pressure disorders. Related Podcast Links: https://directory.libsyn.com/episode/index/id/28479644 https://directory.libsyn.com/episode/index/id/28567413 https://directory.libsyn.com/episode/index/id/28675078 Disclosures can be found at Neurology.org

Dr. Shuvro Roy talks with Dr. Monica T. Ly about brain lesions in former football players linked to vascular brain changes. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Tesha Monteith talks with Dr. Cecilia Hvitfeldt Fuglsang about the effects of migraine and PIH on the risk of stroke and myocardial infarction. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Deanna Saylor talks with Prof. Mayowa Owolabi about reducing the global burden of stroke. Read the related article in Lancet Neurology.

Dr. Halley Alexander talks with Dr. Genna Waldman about her presentation at the AES (Annual Epilepsy Society) symposium session reviewing PNEE (psychogenic non-epileptic events) and indications of discontinuation of medications. Articles referenced in the episode: https://doi.org/10.1111/epi.12356 https://www.sciencedirect.com/science/article/pii/S1059131119300342 https://onlinelibrary.wiley.com/doi/epdf/10.1002/brb3.2567 https://doi.org/10.1111/j.1528-1167.2010.02696.x https://doi.org/10.1016/j.yebeh.2021.108004 Disclosures can be found at Neurology.org.

Dr. Stacey Clardy talks with Dr. Geoff Ling about his thoughts on rapid-fire mortar shooting and more broadly, how he goes about identifying what veterans have been exposed to and treating veterans in the clinic. They also discussed a little bit about a recently published article in the New York Times titled, "A Secret War, Strange New Wounds, and Silence from the Pentagon." Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Dr. Elsmarieke van de Giessen and Emma Coomans about a newly FDA-approved tau-binding radiotracer [18F]flortaucipir and an accompanying visual read method to support the diagnostic process in cognitively impaired patients assessed for Alzheimer disease. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Gordon Smith talks with Prof. Mike Lunn about the relationship between COVID-19 vaccinations and Guillain-Barré syndrome using the National Immunoglobulin Database. Read the related article in Brain. Disclosures can be found at Neurology.org.

Dr. Derek Stitt talks with Dr. Ali A. Habib about trends in hospital admissions and in-hospital mortality for adult patients with MG. Read the related article in Neurology®. Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Dr. Benjamin N. Rome about ways to improve pharmacy benefit managers and the way they function in the system. Read the related article in The New England Journal of Medicine. Referenced in this Episode: June 2021 Neurology Recall Episode Disclosures can be found at Neurology.org.

Dr. Gordon Smith talks with Dr. Haya Bishara about the association between GBS and both SARS-CoV-2 infection and the COVID-19 vaccine. Read the related article in Neurology. Disclosures can be found at Neurology.org.

The January 2024 replay starts the new year off with four previously posted episodes on dementia. The episode begins with an interview with Dr. Kenneth Langa on the prevalence of dementia and mild cognitive impairment in the US. The episode continues with an interview with Dr. Beau Ances about the burden amyloid has on individuals with Down syndrome compared to autosomal dominant Alzheimer disease. The next interview is with Dr. Erik Musiek on the use of lecanemab in early Alzheimer disease. The fourth and final interview is with Dr. Vijay Ramanan on the eligibility for anti-amyloid treatment. Related Podcast Links: Estimating the Prevalence of Dementia and Mild Cognitive Impairment in the United States: https://directory.libsyn.com/episode/index/id/25811241 Comparison of Amyloid Burden in Individuals with Down Syndrome Versus Autosomal Dominant Alzheimer Disease: https://directory.libsyn.com/episode/index/id/25881414 Lecanemab in Early Alzheimer Disease: https://directory.libsyn.com/episode/index/id/25428333 Eligibility for Anti-Amyloid Treatment: https://directory.libsyn.com/episode/index/id/28300052 Related Article Links: Estimating the Prevalence of Dementia and Mild Cognitive Impairment in the US: https://jamanetwork.com/journals/jamaneurology/article-abstract/2797274?resultClick=1 Comparison of Amyloid Burden in Individuals with Down Syndrome Versus Autosomal Dominant Alzheimer's Disease: A Cross-Sectional Study: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(22)00408-2/fulltext Eligibility for Anti-Amyloid Treatment in a Population-Based Study of Cognitive Aging: https://www.neurology.org/doi/10.1212/WNL.0000000000207770 Disclosures can be found at Neurology.org

Dr. Jeff Ratliff talks with Drs. Divya Singhal and Myriam Abdennadher about work-life, parenting, and the well-being of neurologists during the COVID-19 pandemic. Read the related article in Neurology: Clinical Practice. Disclosures can be found at Neurology.org.

Dr. Andrew Southerland talks with Dr. Franzi Herpich about her journey of experiencing a stroke in 2021 as part of our physician-as-patient series. Previously Posted Content: April 2022 Neurology Recall: Physician as Patient Disclosures can be found at Neurology.org.

Dr. Adam de Havenon talks with Dr. Gustaf Edgren about the potential transmissible risk associated with some types of spontaneous intracerebral hemorrhage in patients who receive transfusions. Read the related article in JAMA. Disclosures can be found at Neurology.org.

Dr. Elizabeth Coon talks with Dr. Mitchell G. Miglis about the frequency of orthostatic hypotension in isolated REM sleep behavior disorder. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Drs. Michael Fox and Jacob Stubbs about their study on brain network associations in substance use disorders. Read the related article in Nature. Disclosures can be found at Neurology.org.

Dr. Farrah Mateen talks with Sumaira Ahmed about The Sumaira Foundation and their global ambassador program for patient advocacy. Learn more about The Sumaira Foundation. Disclosures can be found at Neurology.org

Dr. Gordon Smith talks with Laynie Dratch about integrating genetic testing into patient care for persons with Amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) spectrum disorders. Read the related article in Neurology: Clinical Practice. Disclosures can be found at Neurology.org

Dr. Andy Southerland talks with Dr. Jonathan Coutinho about the accuracy of using EEG in the detection of large vessel occlusion stroke in prehospital settings. Read the related article in Neurology. Disclosures can be found at Neurology.org

The December 2023 replay wraps up the year with four previously posted episodes on neurocritical care. The episode begins with an interview with Dr. Karin Diserens on subtle clinical signs in unresponsive brain-impaired individuals. The episode continues with an interview with Dr. David Greer on updated brain death guidelines. The next interview is with Dr. Monica Lemmon on communicating information about neurologic prognosis. The fourth and final interview is with Drs. Susanne Muehlschlegel and Adeline Goss on the prognostic language used in critical neurologic illness. Related Podcast Links: Subtle Clinical Signs in Unresponsive Brain Impairment: https://directory.libsyn.com/episode/index/id/27124839 Updated Pediatric and Adult BD/DNC Consensus Guidelines: https://directory.libsyn.com/episode/index/id/28537073 A Parent-Informed Approach to Communicating Neurologic Prognosis in Infants: https://directory.libsyn.com/episode/index/id/25988781 Language Use in Neurocritical Illness Prognostication: https://directory.libsyn.com/episode/index/id/28137575 Related Article Links: A Focus on Subtle Signs and Motor Behavior to Unveil Awareness in Unresponsive Brain-Impaired Patients: The Importance of Being Clinical: https://doi.org/10.1212/WNL.0000000000207067 Pediatric and Adult Brain Death/Death by Neurologic Criteria Consensus Guideline: Report of the AAN Guidelines Subcommittee, AAP, CNS, and SCCM: https://doi.org/10.1212/WNL.0000000000207740 The ALIGN Framework: A Parent-Informed Approach to Prognostic Communication for Infants With Neurologic Conditions: https://doi.org/10.1212/WNL.0000000000201600 Prognostic Language in Critical Neurologic Illness: A Multicenter Mixed-Methods Study: https://doi.org/10.1212/WNL.0000000000207462 Disclosures can be found at Neurology.org

Our 2023 November Headache series wraps up with Dr. Tesha Monteith talking with Dr. Stewart Tepper about rapid developments in neuromodulation. Disclosures can be found at Neurology.org

Dr. Tesha Monteith talks with Dr. Peter Goadsby about updates on migraine treatments and the integration of CGRP inhibitors into clinical practice. Disclosures can be found at Neurology.org

Dr. Tesha Monteith talks with Dr. Messoud Ashina about the mechanisms of migraine. Articles Referenced in this Episode: Calcitonin Gene-related Peptide Causes Migraine Aura An Exploratory Analysis of Clinical and Sociodemographic Factors in CGRP-induced Migraine Attacks: A REFORM Study Disclosures can be found at Neurology.org

Dr. Andrew Southerland talks with Dr. Seemant Chaturvedi about exciting new trials that have come out in the world of stroke that were presented at this year's World Stroke Congress. Read more on the World Stroke Congress page. Disclosures can be found at Neurology.org

Dr. Tesha Monteith talks with Drs. Deb Friedman and Kathleen Digre about the diagnosis and management of idiopathic intracranial hypertension and cerebrospinal fluid pressure disorders. Disclosures can be found at Neurology.org

Dr. Farrah Mateen talks with Dr. Teddy Totimeh about the urgent need to improve/develop existing and nonexistent neuro-oncology infrastructure, personnel, and logistics across borders. Read the related article in World Neurosurgery. Disclosures can be found at Neurology.org

Dr. Tesha Monteith talks with Dr. Stephanie Nahas about commonly missed and lesser-known primary headache disorders. Disclosures can be found at Neurology.org

Dr. Halley Alexander talks with Dr. David Greer about updating and clarifying the brain death/death by neurologic criteria guidelines for adult and pediatric patients. Read the related article in Neurology. Visit NPub.org/Podcast for associated article links. Disclosures can be found at Neurology.org

Dr. Tesha Monteith talks with Drs. Hayrunnisa Bolay, KC Brennan, and Gianluca Coppola about the International Headache Conference that took place in September and clinical advances in headache medicine. Read more about the 2023 IHC. Disclosures can be found at Neurology.org

The November 2023 replay of past episodes showcases five interviews on topics in stroke. The episode begins with an interview with Dr. Imogene Scott on prehospital telestroke vs paramedic scores to accurately identify stroke reperfusion candidates. The episode continues with an interview with Dr. David Seiffge on the use of oral anticoagulants on ischemic stroke. The next interview is with Dr. Alejandro Rabinstein and Hassan Kobeissi on comparing outcomes between CTP and NCCT for endovascular therapy selection in the late therapeutic window. The fourth interview is with Dr. Thanh Nguyen discussing whether dual antiplatelet therapy is non-inferior to intravenous thrombolysis among patients with minor non-disabling acute ischemic stroke. The November Recall concludes with Dr. Seemant Chaturvedi discussing this year's European Stroke Organization Conference and pivotal trials that were presented during the conference. Related Podcast Links: Pre-Hospital Evaluation of Acute Stroke: EMS vs Telemed: https://directory.libsyn.com/episode/index/id/24928863 Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants: https://directory.libsyn.com/episode/index/id/25736865 CT Perfusion vs CT for Late Window Stroke Thrombectomy: https://directory.libsyn.com/episode/index/id/26673237 Dual Antiplatelet Therapy vs Alteplase for Patients With Acute Ischemic Stroke: https://directory.libsyn.com/episode/index/id/27455412 Pivotal Stroke Trials Presented at this Year's ESOC: https://directory.libsyn.com/episode/index/id/27279144 Related Article Links: Prehospital Telestroke vs Paramedic Scores to Accurately Identify Stroke Reperfusion Candidates: A Cluster Randomized Controlled Trial: https://n.neurology.org/content/99/19/e2125 Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants: https://jamanetwork.com/journals/jamaneurology/fullarticle/2799622 CT Perfusion vs Noncontrast CT for Late Window Stroke Thrombectomy: A Systematic Review and Meta-analysis: https://n.neurology.org/content/100/22/e2304 Dual Antiplatelet Therapy vs Alteplase for Patients With Minor Nondisabling Acute Ischemic Stroke: The ARAMIS Randomized Clinical Trial: https://jamanetwork.com/journals/jama/article-abstract/2806532 ESOC Plenary: https://2023.eso-conference.org/programme/plenary-highlights/ Disclosures can be found at Neurology.org

Dr. Stacey Clardy talks with Drs. Brian Stamm and Behnam Sabayan about the spectrum of clinical presentations, neuroimaging patterns, and the predictors of radiographic and clinical outcomes from diffusion-restricted splenial lesions. Read the related article in Neurology: Clinical Practice. Visit NPub.org/Podcast for associated article links. Disclosures can be found at Neurology.org

Dr. Jeff Burns talks with Dr. Natalia Rost about the AAN's brain health initiative. Read the related article in Neurology. Visit NPub.org/Podcast for associated article links.

Dr. Jennifer Majersik talks with Samantha Cote about the relationship between lifetime hormone exposure and cerebral small vessel disease in postmenopausal women in the UK-Biobank. Read the related article in Neurology. Visit NPub.org/Podcast for associated article links.

Dr. Kait Nevel talks with Dr. Philipp Karschnia about the assessment on whether MTHFR polymorphisms affects the risk for leukoencephalopathy. Read the related article in Neurology. Visit NPub.org/Podcast for associated article links.