Neurology® Podcast

Dr. Jeff Ratliff talks with Dr. Calum Alexander Hamilton about the importance of tracking and managing patients with MCI, especially those with Lewy body pathology. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Stacey Clardy talks with Dr. Nicola de Souza about neuropsychological profiles of deployment-related mild traumatic brain injury and post-traumatic stress disorder among service members and veterans. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Dr. Daniel Weintraub about the long-term dementia risk in Parkinson disease using data from two large, ongoing, prospective, observational studies. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Dr. Eduardo De Pablo-Fernández about the strengths of DAT imaging in diagnosing patients with Parkinsonian disorders. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Dan Ackerman talks with Dr. Luciano A. Sposato about the topic of embolic stroke of undetermined source and the controversies surrounding cardiac monitoring and anticoagulation. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Dan Ackerman talks with Dr. Gaspard Gerschenfeld about the efficacy and safety of both thrombolytics in patients with large ischemic core. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Dr. Colin Hoy about the concept of prodromal Parkinson disease and the ethical considerations surrounding its diagnosis. Read the related article in Neurology. Disclosures can be found at Neurology.org.

The August 2024 recall showcases four previously posted episodes on the topic of Multiple Sclerosis. In the first episode, Dr. Géraldine Androdias discusses the impact of immune checkpoint inhibitors on multiple sclerosis. The episode leads into Dr. Bob Fox discussing the relationship between sNfL levels and radiologic activity in multiple sclerosis. In the third episode, Dr. Ellen Iacobaeus discusses the clinical characteristics of late-onset multiple sclerosis. The last episode leads into a conversation with Dr. Riley Bove discussing navigating family planning and pregnancy in patients with multiple sclerosis. Article Links: Impact of Immune Checkpoint Inhibitors on the Course of Multiple Sclerosis Temporal Relationship Between Serum Neurofilament Light Chain and Radiologic Disease Activity in Patients With Multiple Sclerosis Clinical Characteristics and Long-Term Outcomes of Late-Onset Multiple Sclerosis: A Swedish Nationwide Study Multiple Sclerosis and Family Planning: A Survey Study of the Patient Experience Podcast Links: Impact of Immune Checkpoint Inhibitors sNfL and Radiologic Disease Activity in Patients With MS Clinical Characteristics and Long-Term Outcomes of Late-Onset MS Multiple Sclerosis and Family Planning Disclosures can be found at Neurology.org.

Dr. Halley Alexander talks with Dr. Kimford J. Meador about perinatal exposure to anti-seizure medications and its effects on creativity and executive function in children. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Matthew Barrett talks with Dr. Michael S. Okun about the caution and deliberation needed in understanding Parkinson disease biomarkers. Read the related viewpoint piece in JAMA Neurology. Disclosures can be found at Neurology.org.

Dr. Andy Southerland talks with Dr. Lidia Moura about the implications of large language models (LLMs) for neurologic care. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Justin Abbatemarco talks with Drs. Michael R. Wilson and John Pluvinage about their discovery of anti-CD320 antibodies in patients with neurologic manifestations of B12 deficiency and discuss the potential implications for diagnosis and treatment. Read the related article in Science. Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Dr. Campbell Le Heron about the association of clinical and neurocognitive factors with apathy in patients with Parkinson disease. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Justin Abbatemarco talks with Dr. Andrew McKeon about the topic of autoimmune neurology, specifically focusing on the antibody CAMKV and its association with autoimmune encephalitis. Read the related article in Annals of Neurology. Disclosures can be found at Neurology.org.

Dr. Jessica Ailani talks with Dr. Ian Carroll about intracranial hypotension, the challenges of diagnosing and treating patients with CSF leaks, and the study's findings. Read the related article in Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

As part of our "Physician as Patient" series, Dr. Andy Southerland talks with Dr. Eric Seachrist about his experience with multiple sclerosis. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Stacey Clardy talks with Dr. Carlayne E. Jackson about the state of neurology and the challenges and opportunities facing the field. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Andy Southerland talks with Dr. Seemant Chaturvedi about recent trials presented at the European Stroke Organization Conference. Show references: Tenecteplase for Ischemic Stroke at 4.5 to 24 Hours without Thrombectomy Rationale and Design of Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events III (TRACE III) Colchicine for Prevention of Vascular Inflammation in Non-CardioEmbolic Stroke (CONVINCE) Intensive Ambulance-Delivered Blood- Pressure Reduction in Hyperacute Stroke This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

The July 2024 replay of past episodes showcases four incredible interviews on infectious and post-infectious neurology. The episode begins with Dr. Alice Tang discussing the association between immune status and herpes simplex virus encephalitis. The episode leads into Dr. Haya Bishara talking about GBS and COVID-19 infection. In the third episode, Dr. Adam de Havenon talks about neurologic diagnoses in the year after COVID-19 vs. Influenza. The episode concludes with Dr. Avindra Nath talking about new research related to post-infectious myalgic encephalomyelitis/chronic fatigue syndrome. Article Links: Herpes Simplex Virus Encephalitis in Patients With Autoimmune Conditions or Exposure to Immunomodulatory Medications Burden of Neurologic Health Care and Incident Neurologic Diagnoses in the Year After COVID-19 or Influenza Hospitalization Association Between Guillain-Barré Syndrome and COVID-19 Infection and Vaccination A Population-Based Nested Case-Control Study Podcast Links: Herpes Simplex Virus Encephalitis Guillain-Barré Syndrome and COVID-19 Infection and Vaccination Neurologic Diagnoses after COVID-19 or Influenza Hospitalization Post-infectious Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Disclosures can be found at Neurology.org.

Dr. Tesha Monteith talks with Dr. Michael Marmura about the definition of refractory headache, the challenges in treating migraine, the role of comorbidities, and the importance of accurate diagnosis. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Stacey Clardy talks with Dr. Natalia Rost about the American Academy of Neurology's groundbreaking brain health initiative. Read more about the Brain Health Initiative. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Tesha Monteith talks with Dr. Jennifer Robblee and Dr. Lawrence Robbins about how to diagnose and manage refractory headaches. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Justin Abbatemarco talks with Prof. Zsolt Illes about the mortality of patients with AQP4 antibody–seropositive neuromyelitis optica spectrum disorder compared with that in the general population. Read the related article in Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Dan Ackerman talks with Dr. Andy Southerland about the impact of glucose control on the risk of symptomatic intracerebral hemorrhage following thrombolysis for acute ischemic stroke. Read the related article in Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Tesha Monteith talks with Dr. Messoud Ashina about the comparison between cortical morphometry to a large sample of people with migraine and healthy controls, as well as across migraine subtypes. Read the related article in Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Dr. Avindra Nath about new research related to post-infectious myalgic encephalomyelitis/chronic fatigue syndrome. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Dan Ackerman talks with Dr. Silja Räty about the outcomes of patients with basilar artery occlusion treated with intravenous thrombolysis (IVT) only and compares IVT with endovascular thrombectomy. Read the related article in Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

The June 2024 replay features four previously showcased episodes on topics in epilepsy. The episode begins with Dr. Genevieve Rayner and Eliza Honybun discussing the relationship between prenatal antiseizure medication exposure and adverse postnatal neurodevelopmental outcomes. The second episode leads into a conversation with Drs. Drs. Jacqueline French and Nora Jandhyala on the recognition of motor vs. non-motor seizures and its effect on the management and treatment of focal epilepsy in adolescents. The episode continues with Dr. Valérie van Hezik-Wester discussing the effectiveness of seizure dogs. The episode concludes with Dr. Fred Lado discussing the updated guidelines for specialized epilepsy centers. Article Links: Neurodevelopmental and Functional Outcomes Following In Utero Exposure to Antiseizure Medication Unrecognized Focal Nonmotor Seizures in Adolescents Presenting to Emergency Departments Effectiveness of Seizure Dogs for People With Severe Refractory Epilepsy Guidelines for Specialized Epilepsy Centers Podcast Links: Neurodevelopmental and Functional Outcomes Following In Utero Exposure to Anti-Seizure Medication Unrecognized Focal Non-Motor Seizures in Adolescents Effectiveness of Seizure Dogs National Association of Epilepsy Centers Updated Guidelines Disclosures can be found at Neurology.org.

Dr. Halley Alexander talks with Dr. Emanuele Cerulli Irelli about the research on seizure recurrence in women with idiopathic generalized epilepsy who switch from valproate to another medication. Read the related article in Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Andy Southerland talks with Dr. Andrea Lendaris about her experience of having Usher syndrome type 2A along with her journey of having acute and chronic health challenges. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Dr. Maureen Leehey about the short-term efficacy and tolerability of high-CBD/low-THC cannabis extract on the motor symptoms in patients with Parkinson disease. Read the related article in the International Parkinson and Movement Disorder Society. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Drs. Sarah Louise Edwards and Zachary London about the current state of game-based learning in neuroscience education. Read the related article in Neurology: Education. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Howard Goodkin talks with Dr. Alison M. Pack about the new updated guidelines piece on the conclusions and recommendations regarding the effects of antiseizure medications and folic acid supplementation on the prevalence of MCMs, adverse perinatal outcomes, and neurodevelopmental outcomes in children born to PWECP. Read the related article in Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Derek Stitt talks with Dr. Adam de Havenon about the burden of neurologic health care and incident neurologic diagnoses in the year after COVID-19 vs influenza. Read the related article in Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Vikram Karnik talks with Dr. Rob de Bie about early vs. delayed start of Levodopa in early Parkinson disease, and what it means for clinical practice. Read the related article in International Parkinson and Movement Disorder Society. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Justin Abbatemarco talks with Dr. Alice Tang about the association between immune status and herpes simplex virus encephalitis. Read the related article in Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information. Disclosures can be found at Neurology.org.

Dr. Halley Alexander talks with Drs. Jacqueline French and Nora Jandhyala about investigating ED recognition of motor vs. non-motor seizures and its effect on the management and treatment of focal epilepsy in adolescents. Read the related article in Neurology. Disclosures can be found at Neurology.org.

The May 2024 replay features four episodes on neuro-oncology for brain cancer awareness month. The episode begins with Dr. Philipp Karschnia discussing the assessment of whether MTHFR polymorphisms affect the risk for leukoencephalopathy. The episode continues with Dr. Ingo Mellinghoff discussing new treatment opinions for isocitrate dehydrogenase (IDH)–mutant grade 2 gliomas. The third interview leads into a conversation with Dr. Linda Liau on the study of vaccine-based therapy for GBM. The episode concludes with Dr. Teddy Totimeh talking about brain tumor programs in Asia and Africa. Podcast Links: MTHFR Polymorphisms and Leukoencephalopathy Risk in CNS Lymphoma Patients New Treatment for IDH mt Gliomas Study of Vaccine-Based Therapy for GBM Brain Tumor Programs in Asia and Africa Article Links: https://doi.org/10.1212/WNL.0000000000207670 https://www.nejm.org/doi/full/10.1056/NEJMoa2304194 https://jamanetwork.com/journals/jamaoncology/fullarticle/2798847 https://doi.org/10.1016/j.wneu.2023.04.067 Disclosures can be found at Neurology.org.

Dr. Justin Abbatemarco talks with Dr. Bob Fox about the relationship between serum neurofilament light chain (sNfL) levels and radiologic multiple sclerosis disease activity. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Justin Abbatemarco talks with Dr. Ellen Iacobaeus about patient characteristics, disease-modifying therapy, and disability progression in Swedish patients with late-onset MS and adult-onset MS over 2 decades. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Dr. Chris Gibbons about the use of skin biopsies to detect phosphorylated α-synuclein in individuals with synucleinopathies such as Parkinson disease, multiple system atrophy, dementia with Lewy bodies, and pure autonomic failure. Read the related article in JAMA. Disclosures can be found at Neurology.org.

As part of our "Physician as Patient" series, Dr. Andy Southerland talks with Dr. Amy Hessler about her experience with a ruptured arteriovenous malformation as a 2nd-year neurology resident. Disclosures can be found at Neurology.org.

As part of our "Physician as Patient" series, Dr. Andy Southerland talks with Dr. Joe Sirven about his experience with a ruptured arteriovenous malformation. If you're attending the AAN Annual Meeting in Denver, you can catch this conversation and more in a live Q&A session on April 16th at 2:30 pm MT at the publication stage. Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff talks with Drs. Dara V. F. Albert and Afsaneh Talai about understanding the gaps in resident education on psychogenic nonepileptic seizures. Read the related article in Neurology: Education. Disclosures can be found at Neurology.org.

Dr. Kait Nevel talks with Dr. Elizabeth Gerstner about the use of CAR-T cells in the treatment of glioblastoma. Read the related article in The New England Journal of Medicine. Disclosures can be found at Neurology.org.

Dr. Justin Abbatemarco talks with Dr. Géraldine Androdias about the impact of immune checkpoint inhibitors on the course of multiple sclerosis. Read the related article in Neurology: Neuroimmunology and Neuroinflammation. Disclosures can be found at Neurology.org.

Dr. Jessica Ailani talks with Dr. Ron (W.P.J.) van Oosterhout about the occurrence, characteristics, and evolution of space headaches during long-duration flights. Read the related article in Neurology. Disclosures can be found at Neurology.org.

The April 2024 replay of past episodes showcases four incredible interviews on functional neurologic disorders. The episode begins with the 3-part FND roundtable discussion with Prof Jon Stone discussing various topics in FND with Drs. Selma Aybek, David Perez, and Sarah Lidstone. In the first discussion they touch on FND diagnosis and exploring new phenotypes. The second discussion is on how and why FND and the third discussion is on treatments for FND. The episode concludes with Dr. Halley Alexander's conversation with Dr. Genna Waldman about reviewing psychogenic non-epileptic events. Related Links: An Updated Round Table Discussion on FND: Diagnosis of FND and New Phenotypes An Updated Round Table Discussion on FND: How and Why Does FND Occur? An Updated Round Table Discussion on FND: Sharing a Diagnosis and Treatment Reviewing Psychogenic Non-Epileptic Events Disclosures can be found at Neurology.org.

Dr. Shuvro Roy talks with Dr. Annette Langer-Gould about the effective dose of rituximab and other B-cell depleting therapies in patients with multiple sclerosis, as well as important comorbidities to prevent infection risks. Read the related article in Neurology: Neuroimmunology and Neuroinflammation. Disclosures can be found at Neurology.org.

Dr. Jeff Ratliff speaks with Dr. Avindra Nath, the recipient of the 2024 American Brain Foundation Ted Burns Humanism in Neurology Award. Read more about the Ted Burns Humanism in Neurology Award. Disclosures can be found at Neurology.org.