Naked Scientists, In Short Special Editions Podcast

Do you like to lie out on the beach in the summer, or are you more likely to be found hiding in the shade? Well, how you answer might depend on how quickly you seem to get sunburnt. We all know that we should wear sunscreen when out and about in the summer to protect our skin and so reduce our risk of skin cancer, but new research from the Weill Medical College of Cornell might allow us to ditch the sunscreen at some point in the future. Eva Higginbotham spoke to Dr Jonathan Zippin, a dermatologist and skin researcher, about his lab's key discovery in the science of skin. Like this podcast? Please help us by supporting the Naked Scientists

When we think of our immune system, most of us will be familiar with the white blood cells that circulate around our body to target and kill the bacteria and viruses that make us sick. But, we actually also have a special type of immune cell sitting in some of our body surfaces, like our skin and our gut, and new research suggests that these cells might hold the key to future cancer and allergy treatments. Eva Higginbotham spoke to Professor Adrian Hayday from the Francis Crick Institute and King's College London, about his new paper describing the unique way these cells actually work, and why... Like this podcast? Please help us by supporting the Naked Scientists

Today marks 100 years since the end of World War 1. This conflict caused the deaths of around 16 million people, and the new developments in artillery meant that new and nasty injuries were defying our ability to treat them. Ironically, this meant WW1 actually lead to huge advances in medicine, and neuroscience. But, thanks to a charity, Headway, it's also helping people with brain injuries today. Georgia Mills has been finding out how Like this podcast? Please help us by supporting the Naked Scientists

We get so many good questions sent to us here at The Naked Scientists, that sadly we can't fit them all into our monthly question and answer shows. So here's an extra slice of science for you from our November 2018 QnA. Roger got in touch to ask whether artificial intelligence will be making medicines in the future, and we also heard from Sean about some rather intelligent ravens... Like this podcast? Please help us by supporting the Naked Scientists

Glioblastoma is an aggressive and often deadly cancer of the brain. Understanding it is vital to improving patient outcomes. In a new study published in Nature Genetics, a group in Cornell University has been sequencing genes to understand which ones are switched on by the tumours. To learn more, Adam Murphy spoke to Charles Danko, of the Baker Institute for Animal Health and the Cornell College of Veterinary Medicine... Like this podcast? Please help us by supporting the Naked Scientists

Good dental hygiene is crucial in the fight against gum disease, which can lead to a common condition called periodontitis. It comes about when changes to the bacteria in the mouth cause a reaction called inflammation in areas around the teeth, potentially destroying tissue and bone and causing tooth loss. But quite why an altered microbiome causes this inflammation isn't known, so there are no targeted treatments, and surgery is the main option for severe cases. But now scientists have spotted that periodontitis patients have higher numbers of immune cells called TH17 cells in their mouths,... Like this podcast? Please help us by supporting the Naked Scientists

Astronomers at the University of Hertfordshire have come up with an explanation for the wobble seen in jets of matter being blasted from regions surrounding some supermassive black holes: Another nearby supermassive black hole! Dr Martin Krause tells us how we can see them at all... Like this podcast? Please help us by supporting the Naked Scientists

Nowadays, tuberculosis takes more lives than any other infectious disease. Cases are on the decline but emerging antibiotic resistance threatens to interrupt that pattern. Tamsin Bell spoke with Professor Francois Balloux from University College London to learn about how this infectious disease evolved... Like this podcast? Please help us by supporting the Naked Scientists

We all know that drinking alcohol is bad for us but in the UK we still pay a huge 3.5 billion annually for the National Health Service (NHS) to treat over 60 alcohol induced medical conditions including liver disease, pancreatitis, diabetes, heart disease and numerous forms of cancer. Fortunately, it seems that the message to put down the booze has trickled down to the younger generation as a recent study of 16 to 24 year olds shows that over the past ten years, they are drinking less. Tamsin Bell spoke to Linda Ng Fat from University College London to find out why more teens are laying off... Like this podcast? Please help us by supporting the Naked Scientists

From right here on earth to the furthest visible parts of the universe, NASA has its eye on pretty much everything in between. Professor Andrew Coates from University College London was lead co-investigator in the joint ESA-NASA Cassini-Huygens mission to Saturn, and is involved in several further NASA missions of space exploration. With NASA turning 60 this month, Sam Brown spoke to Professor Coates about the fascinating missions that NASA is involved with, and what they have planned for the future... Like this podcast? Please help us by supporting the Naked Scientists

Mosquitoes spread diseases like malaria, and they are rapidly becoming resistant to the insecticides used to control them. So scientists are looking at the potential of using a genetic technique, called a gene drive, to solve the problem. This involves engineering a gene-editing system into the insects that targets and inactivates a gene called dbx - or doublesex - that is needed for the insects to develop normally. Critically though, only female mosquitoes, which are also the ones that bite, are affected by the change. This means that males are left unaffected and can spread the genetic... Like this podcast? Please help us by supporting the Naked Scientists

Antibiotic resistance is one of the greatest threats facing mankind today. A new group in the University of Washington in Seattle, have been working to fight this threat. In a new study, they've been looking to poison bacteria using the heavy metal gallium, to improve the lives of those with cystic fibrosis. Adam Murphy spoke to two authors of the study. First, Christopher Goss and then colleague, Pradeep Singh... Like this podcast? Please help us by supporting the Naked Scientists

Imagine going into space. You've got your kit, you're blasted into darkness, you're ready to discover the unknown but then your equipment doesn't quite fit the task required. How can you prepare for that? This is a reality that space engineers and robotic experts are trying to facing every day. Now, researchers from Yale think they've got an answer. They've developed something called "Omniskin" - a sheet of material that can animate everyday objects and turn them into robots. Izzie Clarke spoke to study author Joran Booth. Like this podcast? Please help us by supporting the Naked Scientists

You may have heard of graphene, the so called wonder material set to revolutionise electronics but the difficulty to consistently add extra properties and scale up cheaply limits industrial use! Scientists have been looking for easy to make alternatives, such as a new class of materials called metal organic frameworks or MOFs. As the name suggests, they're made by combining two components: a metal and something called an "organic chain" which contains carbon with some other elements. These can be used to create new materials with exciting properties.The big problem is that scientists have not... Like this podcast? Please help us by supporting the Naked Scientists

Do you share food or do you bite the hand off anyone who tries? Chimpanzees, one of our closest relatives are in the latter category: they'll gladly share tools, but food's a no no. New research published in Proceedings of the Royal Society B has been looking into our other close relatives: bonobo apes. Bizarrely, while they'll gladly share food, woe betide anyone who touches someone else's tools or toys! So what does this say about us? Adam Murphy spoke to Christopher Krupenye, from the University of St. Andrews to learn more. Like this podcast? Please help us by supporting the Naked Scientists

We've all been there at some point - you raise your hand in class, answer the question, and get it utterly, utterly wrong. These school-day humiliations may stay with us many years later, in fact - I'd love to hear yours, but as our kids are all headed back to school this week, we're trying to find out if perhaps these mistakes are good for us! Georgia Mills is on the case, but only after finding out some of our listeners biggest dunce moments! Like this podcast? Please help us by supporting the Naked Scientists

These days, many of us are heavily dependent on our trusty sat navs to get where we want to go, but looking at these devices whilst driving is incredibly dangerous and can lead to car accidents. Psychologists from Anglia Ruskin University are hoping to minimise the dangers of using this technology by incorporating audio cues with in-car GPS to forewarn the driver of the lay of the land. Tamsin Bell met with Helen Keyes to hear what's driving their work... Like this podcast? Please help us by supporting the Naked Scientists

Goats can tell apart human facial expressions and - what's more - prefer to interact with happy people, according to a new study from scientists at Queen Mary University of London. We knew work animals like dogs and horses could do this, but no-one knew if animals domesticated for food products would be able to. Georgia Mills spoke to lead researcher Alan McElligott to find out how they did it Like this podcast? Please help us by supporting the Naked Scientists

Most of the people who develop cancer are adults, although a significant number of children succumb too. The signs are though that childhood cancers could have a different origin than the adult disease, which might also mean they can be treated in a different way. Cambridge University's Sam Behjati suspects that tumours in children form from foetal tissue that has failed to mature properly. And by comparing the genetic instructions operating in normal and cancerous kidney cells from children and adults, he's tracked down evidence to support his theory and found a host of new avenues to explore... Like this podcast? Please help us by supporting the Naked Scientists

From artificial photosynthesis to the art of statistics, the Naked Scientists take Jenny Zhang and Richard Samworth, two of St John's College's leading scientists, for a trip down the river to hear all about their work. Like this podcast? Please help us by supporting the Naked Scientists

Doctors think that one third of the world's population have been exposed to the bacterial infection TB, or tuberculosis. It can damage any tissue in the body, infect the skeleton and joints, and even cause meningitis, but most people develop chest disease and a cough, which is how it chiefly spreads. A major problem with controlling the infection is that the Mycobacterium tuberculosis bacteria can be very hard to culture in a laboratory, and they grow extremely slowly, which holds up diagnosis and also makes it tricky to tell quickly whether someone is actually responding to the treatment... Like this podcast? Please help us by supporting the Naked Scientists

We often hear about the search for life on Mars, but could life begin outside our solar system? Izzie Clarke discussed the chemistry involved with astrophysicist Paul Rimmer... Like this podcast? Please help us by supporting the Naked Scientists

Since Darwin's time scientists have been studying the skeleton of a type of fish that lived 400 million years ago called Heterostracans. These fish were covered in a tough exoskeleton, but scientists couldn't decide exactly where it came from. Was it a precursor to bone? To teeth? New research is suggesting all those old theories may be as dead and buried as the fish fossils, and this exoskeleton is just another way of making bone. Adam Murphy spoke to Joseph Keating of the University of Manchester to learn more... Like this podcast? Please help us by supporting the Naked Scientists

HIV is a global pandemic. Worldwide, about 37 million people are living with the virus, and there are between 3 and 5 thousand AIDS deaths every day. More worrying is that, despite intensive public health and safe sex campaigns, there are a further 3 to 5 thousand new HIV infections occurring every day, and despite decades of effort, scientists still have not yet managed to develop an effective vaccine. But one very powerful way to prevent infection is for men to be circumcised, which reduces their risk of picking up the virus by up to 80%. So is this a cost effective strategy to halt HIV... Like this podcast? Please help us by supporting the Naked Scientists

Mixing chemicals together causes reactions and produces new molecules. With so many different chemicals in existence, there are infinite combinations that can be made, and millions of chemical reactions yet to be tried. But doing these tests is very time consuming, laborious and has a low success rate; it's also very susceptible to human failings, like bias and fatigue. To surmount this, University of Glasgow chemist Lee Cronin has invented a robot to test his chemical combinations for him. What's more impressive is that this robot can actually learn. By testing random chemical combinations... Like this podcast? Please help us by supporting the Naked Scientists

Vitiligo is an autoimmune condition, in which the immune system attacks the pigment-producing cells of the skin, leaving behind pale white patches. Although not dangerous in itself, vitiligo can be disfiguring, causing a great deal of distress to people suffering from it. There are treatments available for vitiligo - these include topical creams that suppress the immune attack on skin cells, and phototherapy, which uses UV light. However, these treatments are time- and effort-consuming, particularly if large areas of the skin are affected. Another problem is that they only work temporarily -... Like this podcast? Please help us by supporting the Naked Scientists

Heart attacks come about when blood vessels in the heart are blocked, and without a supply of oxygen-rich blood, the heart muscle can die. This is called ischemic injury, and can also occur in other places in the body, potentially leading to tissue death and even limb amputation. But what if it was possible to re-build the blood vessels in the heart or in other areas of the body, to kick-start the circulation and prevent tissues from being starved of oxygen, and dying? This is what Jo Mountford is trying to do at the Scottish National Blood Transfusion service, as she explains to Katie... Like this podcast? Please help us by supporting the Naked Scientists

People all around the world are living the high life. That's to say, living their whole lives at high altitude. This lifestyle has an impact on their bodies, including upon how their bones grow. And one adaptation, Cambridge University's Stephanie Payne has found, is to alter the relative lengths of the arms. Katie Haylor and Chris Smith found out more... Like this podcast? Please help us by supporting the Naked Scientists

Scientists want to raise awareness to protect the Earth from dangerous asteroids. June 30th has now become Asteroid Day where people from around the world come together to learn about asteroids, the impact hazard they may pose, and what we can do to protect our planet, families, communities, and future generations from future asteroid impacts. Izzie Clarke spoke to Matt Bothwell and Adrian Currie at the University of Cambridge to learn more... Like this podcast? Please help us by supporting the Naked Scientists

4 billion years ago, life on earth looked nothing like it does today. In fact, the oceans contained only single-celled microbes. At some point, these single-celled organisms began to work together, forming complex, multi-celled creatures, which then suddenly became much larger. The question is, why? Emily Mitchell studies one of the earliest animals believed to exist, and explained to Marika Ottman why she thinks these creatures got bigger when they did Like this podcast? Please help us by supporting the Naked Scientists

In recent years, we've woken up to the massive problem that is dementia. This is where people progressively lose their cognitive faculties and Alzheimer's Disease is one well-known example. But scientists are increasingly realising that injury done to the brain by damaged blood vessels is probably the leading cause of dementia, but it's also the one that we know much less about. It happens when the very small blood vessels deep within the brain become narrowed, stiffened and leaky, which leads to progressive damage to the adjacent brain tissue, although we don't understand how this happens, or... Like this podcast? Please help us by supporting the Naked Scientists

Osteoarthritis, a condition which damages the cartilage in joints, is a painful, debilitating condition. Millions suffer every year, and with an ageing population, that number will only increase. Therefore, improving diagnosis is an important goal. Adam Murphy spoke with Tom Turmezei from Cambridge University, to learn more about osteoarthritis and his Wellcome Trust funded project which aims to improve diagnosis... Like this podcast? Please help us by supporting the Naked Scientists

If robots really are the future, then said future is certainly one step closer as of this week. For the first time ever, a robot has been used in surgery on the human eye. To find out more about this incredible feat of engineering, Isabelle Cochrane spoke to Dr Tom Edwards, the lead author of the study... Like this podcast? Please help us by supporting the Naked Scientists

CRISPR makes it possible to snip out undesired bits of DNA from our cells. This process holds the potential to cure genetic conditions such as cystic fibrosis. However, it seems that doing this isn't without risk. Marika Ottman went to the University of Cambridge and spoke with biochemist Jussi Taipale to learn more... Like this podcast? Please help us by supporting the Naked Scientists

Researchers have found a way to regenerate the enamel - or apatite - that's damaged by tooth decay. Katie Haylor spoke to Alvaro Mata from Queen Mary University of London...Sound effects from www.zapsplat.com Like this podcast? Please help us by supporting the Naked Scientists

We know more about the surface of mars than we do about the depths of our own ocean, but scientists from the California Academy of Science created an invention that allows researchers to bring never-before seen species from coral reefs in the deep sea to the ocean's surface. In the spirit of World Ocean's day tomorrow, Marika Ottman spoke with lead author Bart Shepherd to learn more... Like this podcast? Please help us by supporting the Naked Scientists

Millions suffer from osteoarthritis, a condition that causes joints, especially knee and hip joints, to become stiff and painful. Luckily these joints can be replaced by an implant with usually good results. However, scientists are going one step further, bringing robots into the operating theatre to improve precision, and patient outcomes. The Nuffield Hospital in Cambridge recently brought in one of these robot helpers, and Chris Smith spoke with the director of the hospital, Adrian Connolly... Like this podcast? Please help us by supporting the Naked Scientists

Any activity on your daily commute, like walking to the bus instead of just hopping in the car, might reduce your risk of cardiovascular disease, says a new study from the University of Cambridge, published in the journal Heart... Like this podcast? Please help us by supporting the Naked Scientists

We all love a good hug, whatever our age! Babies are no different. There's growing evidence that skin-to-skin contact is beneficial for babies, so Katie Haylor spoke with Laura Baird and Kelly Spike from Addenbrookes Hospital in Cambridge to find out what it's all about... Like this podcast? Please help us by supporting the Naked Scientists

Hawaii's Big Island has been experiencing a series of volcanic eruptions. What's causing them, and how is it likely to change in the future? To find out, Chris Smith talked to Jessica Johnson, a volcanologist at the University of East Anglia... Like this podcast? Please help us by supporting the Naked Scientists

Exercise is good for us, it's one of the best things you can do to keep your mind and body healthy for a long age. But perhaps not all exercise is equal. A new analysis out in the British Journal of Sports Medecine reports that exercise at work is associated with an increased risk of early death in men. So what's going on? Georgia Mills spoke to study author Pieter Coenen, of VU University in Amsterdam. Like this podcast? Please help us by supporting the Naked Scientists

Knowing where Earth's freshwater is accumulating, or perhaps more critically, disappearing is of paramount importance. A new study in Nature has analysed changes in freshwater across the entire planet. To learn more Adam Murphy spoke with Matthew Rodell, from the NASA Goddard Space Flight Centre in Greenbelt, Maryland... Like this podcast? Please help us by supporting the Naked Scientists

Neurodegeneration is a process involved in several serious and debilitating diseases, for which there is often no cure. One of the first steps on the journey towards a treatment to stop neurons dying is understanding how and why they do so. Now, scientists from Cambridge University and the University of Toronto have announced a mechanism that explains how neurons die in two diseases, motor neurone disease and a type of dementia called fronto-temporal dementia. Georgia Mills spoke to Cambridge University chemist Michele Vendruscolo. First, Georgia asked, what actually are neurons? Like this podcast? Please help us by supporting the Naked Scientists

Are you struggling to know what to wear for the weather at the moment? One day in the UK it's freezing, the next rain, the next a veritable heat wave. Apart from playing havoc with BBQ plans, this extreme variation in weather is also affecting local wildlife. Georgia Mills went for a stroll along the river Cam with the RSPB's Richard Bradbury to find out more. Like this podcast? Please help us by supporting the Naked Scientists

Tasmanian devils are black, carnivorous, scavenger marsupials that live - perhaps unsurprisingly, on the island of Tasmania. In recent years an intriguing type of cancer has been decimating their numbers, pushing the animals to the brink of extinction. Known as "Devil Facial Tumour Disease" - or DFTD - the cancer is spread when an affected animal bites - and literally implants - some of the tumour from its own mouth into the face of another devil. The tumours avoid detection by the immune system by switching off key markers that would normally label the tissue as foreign. Now, by studying the... Like this podcast? Please help us by supporting the Naked Scientists

Every year millions of people contract malaria, which is a blood parasite infection spread by mosquitoes. And part of the reason why the infection spreads so successfully, scientists now know, is because the parasite makes an infected human over-produce certain skin odours that are irresistible to a mosquito. Chris Smith spoke to Ailie Robinson, researcher at the London School of Hygiene and Tropical Medicine and the lead author on the new study that's uncovered how this happens Like this podcast? Please help us by supporting the Naked Scientists

Motorneurone Disease (MND), which is also known as ALS and Lou Gehrig's Disease, is caused by the death of the motor nerves that convey movement instructions from the nervous system to muscles. We don't understand why this happens, but up to 10% of cases appear to be genetic. Now Babraham Institute researcher Jemeen Sreedharan has genetically engineered into a mouse the same genetic change that causes MND in humans. His animals are now providing us with new insights into the pathological process that underlies MND, as he explains to Chris Smith...Jameen - Motorneurone disease is an... Like this podcast? Please help us by supporting the Naked Scientists

Motor neurone disease (MND) is a degenerative disease affecting around 5,000 people in the UK. It attacks people's ability to move, speak and breath, and usually is fatal within two years. At the moment there is no cure, but scientists are trying to find out more about what causes MND and how we might one day treat it. This week, a paper out in Nature Neuroscience describes a new model for MND, which has revealed some unexpected clues about how the disease operates, and may even lead to a target for treatments. Chris Smith spoke to one of the authors Jemeen Sreedheren, from Cambridge... Like this podcast? Please help us by supporting the Naked Scientists

When people take wildlife products over a border that is under the control of CITES. Some of it is illegal, and this is when Border Force step in, confiscating the items in question and when possible, returning them to the wild. But what do people bring through? Georgia Mills was shown the Dead Shed, by senior Border Force officer Grant Miller, a horrific stash of animal and plant products that had been confiscated at Heathrow Airport. This content may be upsetting to some people. Like this podcast? Please help us by supporting the Naked Scientists

Multiple Sclerosis, or MS, affects hundreds of thousands of people. It's a condition where the body's own immune system attacks a protective layer around nerve fibres called myelin. This prevents messages being conveyed quickly and faithfully through the brain producing symptoms that can include difficulty with vision, movement, speech, balance and sensation. In recent years scientists have begun to explore the use of stem cells to combat the progression of the disease. As author Stefano Pluchino, from Cambridge University, explained to Chris Smith. Like this podcast? Please help us by supporting the Naked Scientists