Finding Genius Podcast

No one likes me. I'm going to fail this exam. I really shouldn't have eaten all that lasagna. Ever have these or similar thoughts? If so, you're not alone. Most of us are overrun by certain thinking patterns, which lead to certain feelings, which lead to certain behaviors. And often, the result is detrimental to our mental and physical health. Tune in to discover: What's unique about the use of CBT in treating anxiety and depression Tips and tricks for dealing with bouts of depression and/or anxiety The importance of psychoeducation and practical skills to reframe negative thoughts A longstanding interest in psychology and the mind-body relationship led Liz Ross to become a licensed psychotherapist who specializes in the application of cognitive behavioral therapy techniques for people dealing with anxiety, depression, and chronic pain. Having spent over a decade in the field, she recounts how things have changed since her early days, like the advent of social media and its impact on mental health, the growing prevalence of virtual therapy, and expectations surrounding therapy. Ross explains cognitive behavioral therapy, describing each component in detail, as well as her approach in treating people who present with certain issues. Tune in for all the details and visit https://drlizross.com/ to learn more. Episode also available on Apple Podcasts: apple.co/30PvU9C

How can GI health significantly determine the general health of the rest of the body? Since so many bodily systems utilize products produced along the gastrointestinal tract, minor issues can be increased throughout the body. Listen up to learn: How the gut microbiome has the potential to make or break the body's health How the Western diet may be threatening your gut's health How "bacterial economics" governs GI systems Executive vice president and chief medical officer at Seres Therapeutics, Dr. Lisa von Moltke, discusses her work developing therapeutic techniques to treat gastrointestinal conditions and microbiomes. Through the study of how the gut microbiome and gastrointestinal health affect the operation of the rest of the body, new therapies have been developed to combat GI-targeted infections. New therapies are also being produced to prevent infection with patients undergoing transplants and grafts. Immunosuppressants are also a weak point regarding gut health since they open windows of vulnerability for infections to target your gut. Therefore, developing techniques to treat various diseases without affecting GI health and the gut microbiome may be the next most valuable step in developing pharmaceutical therapeutics. For more information, visit serestherapeutics.com. Episode also available on Apple Podcasts: apple.co/30PvU9C

Dr. Brian Hooker is an Associate Professor of Biology at Simpson University. He specializes in microbiology and biotechnology and has a keen interest in the importance of inoculation and the safety of childhood inoculation. He has written numerous articles about childhood inoculation side effects including allergies, developmental delays, infections, and neurodevelopmental disorders. He is currently interested in the association between the cv1-9 inoculation and subsequent health issues such as the number of adverse events and deaths thought to be related to the inoculation. Click on play to learn: How inoculation has become lucrative for pharmaceutical companies. What studies of uninoculated children reveal about the side effects of childhood inoculation. What long-term and acute effects are being associated with childhood and cv1-9 inoculation. Childhood inoculations are meant to protect children from serious and potentially fatal diseases such as measles, polio, diphtheria, mumps, rubella, and others. Sometimes, a child has an adverse reaction after getting inoculate that may be linked to the inoculation itself. Some of those reactions include developmental delays, autism, allergies, ear infections, ADD, and ADHD. However, the medical community does not acknowledge any links between childhood inoculation and these types of reactions. Dr. Hooker has an interest in medical epidemiology and adverse events and has been doing research on childhood inoculation and possible reactions. Using data retrieved through 2016 from the Inoculation Safety Datalink, his studies have found that uninoculated children seem to have fewer chronic disorders and appear to be healthier than children who received inoculations on schedule. Some adverse reaction events surrounding the cv1-9 inoculation have lead to questions about the safety, testing, and effectiveness of the inoculation. The issue of mandated inoculation by corporations and educational institutions and the possibility of a inoculate passport have raised questions relating to the infringement of the civil rights of U.S. citizens. Dr. Horn discusses these issues, the power of big pharma companies, and inoculation pros and cons. To learn more visit: childrenshealthdefense.org childrenshealthdefense.org/defender Episode also available on Apple Podcasts: apple.co/30PvU9C

Janet Hays, founder of Healing Minds NOLA, is a formidable advocate for those who suffer from severe mental illness in New Orleans and across the country. She works tirelessly to bring those afflicted with mental illness, their families, and other stakeholders together to find a path to more productive and humane treatments of mental illness. Click on play to learn: Why someone who is mentally ill ends up being incarcerated instead of being admitted to a hospital for treatment. How anosognosia impairs a person's ability to acknowledge their mental illness and subsequent refusal of treatment. What the vision is for assisted outpatient treatment (AOT). Janet Hays has been instrumental in New Orleans in shining a spotlight on the mismanaged mental health care system for more than six years. Having witnessed the inadequacies of mental health care in the United States, Hays has made it her life's work to advocate for better ways to care for the mentally ill. Her vision includes residential treatment communities, assisted outpatient treatment, and even clubhouses to provide a venue for the mentally ill to reconnect to the community and make new friends. One of the issues that impedes medical treatment is anosognosia, a medical condition that impairs the ability of the individual recognize that they suffer from mental illness. They are unaware of their mental health condition, or they do not understand it correctly. The perception of their mental health can shift back and forth over time which adds to the belief that the person is denying the condition to avoid seeking treatment. One of the proposed plans for the treatment of mental illness is AOT, a community-based program of providing mental health treatment under civil court commitment. One of the objectives of the AOT program is to unite and encourage the mental health system in taking responsibility for collecting the necessary evidence of mental illness and prepare a petition for AOT to present to the court so the individual can receive the treatment they need. To learn more visit: https://healingmindsnola.org https://treatmentadvocacycenter.org Episode also available on Apple Podcast: http://apple.co/30PvU9C @HealingMindsNO

Imagine feeling perfectly healthy and heading to your doctor for a simple cholesterol check, only to be told your blood work indicates that you may have an extremely rare, aggressive form of cancer. This is how most people are diagnosed with T-cell prolymphocytic leukemia (T-PLL). Dr. Marco Herling specializes in this type of cancer and shares his insights with listeners. Press play to learn: The difference between leukemia and lymphoma How the study of T-cell prolymphocytic leukemia (T-PLL) has led to a change in its name, and why it matters The most common physiological findings in patients who end up with a T-PLL diagnosis Why T-PLL is mostly a disease of the elderly, and the one exception Dr. Herling is an adjunct assistant professor in the Department of Hematopathology at the MD Anderson Cancer Center who was drawn to the study of T-PLL precisely because it is so rare and so understudied. In fact, he explains that most doctors struggle to diagnose it correctly and refer patients to the proper treatment. This lack of understanding exists even in large-volume academic centers and major university hospitals. In Western and European countries, the incidence of T-PLL is low, at about one to two cases per one million each year. "International networking is of the essence in order to make progress in this disease," says Dr. Herling. He explains how T-PLL is generally diagnosed, the signs and symptoms of the disease, theories about why and how it develops, and possible ways to detect and eliminate it earlier on. He also talks about the current efforts being made to further the study and understanding of T-PLL, which hold promise for an eventual effective treatment. Interested in learning more? Tune in, and visit https://herlinglab.com/. Episode also available on Apple Podcast: http://apple.co/30PvU9C

Is cancer its own separate organism? While we believe that it may not be most of the time, some instances of contagious cancer variants do not die with the host. Listen in to learn: How cancers may first arise Why metastatic sites hold vital clues to begin understanding metastasis How to backtrack a tumor to see how it may have formed Courtenay C. and Lucy Patten Davis Endowed Chair in Lung Cancer Research, James DeGregori, shares his expertise on various forms of cancer and the theoretical questions of the future. Many people think that random mutations may be the root cause of many forms of cancer. However, new research disputes this, and specialists have begun on a new research path of carcinogens and their effects on the body. While they may cause a higher rate of mutations in the area they affect, carcinogens seem to have many other impacts as well. The critical component of the speculation surrounding cancer is the "why?" of the developing tumors in specific areas that may not be favorable for it. By determining the traits present in particular cells where the tumor began, the genetics can be deciphered, providing a complete image of cancer's development. Visit degregori-lab for more information. Episode also available on Apple Podcasts: apple.co/30PvU9C

You may be familiar with cicadas but are you aware of the vast impact they have on the environment. A cicada emergence can leave lasting effects on the world around them. Press play to learn: What years cicadas emerge Why cicadas live most of their life underground What Samuel Ramsey plans on studying next Samuel Ramsey, founder and director of the Ramsey Research Foundation, joins the podcast to discuss his research regarding parasitic insects and the wondrous world of cicadas. While many refer to them as locusts, there is much that distinguishes cicadas, and they have a vast benefit on the world around them. Unlike what we may have previously believed, cicadas bring benefits that can have favorable effects on crops and the ecosystem they emerge in. From having a boon on growth and providing vast energy sources for animals across the ecosystem, the 13 and 17-year broods can have an incredible impact. By studying emergence patterns and the lifespans of cicadas, information can be gleaned on many natural systems. Search for Samuel Ramsey on Twitter at @drsammytweets Episode also available on Apple Podcasts: apple.co/30PvU9C

Dr. George Calin holds M.D. and Ph.D. degrees from Carol Davila University of Medicine in Bucharest, Romania. He completed cancer genomics training at the University of Ferrara in Italy and was a post-doctor fellow at the Kimmel Center in Pennsylvania. The focus of his work is exploring new RNA therapeutic options for cancer patients. Click on play to learn: Why research on non-coding RNAs is important and what makes them special. How studies of ultraconserved gene sequences led to the discovery of distinct signatures in human cancers. How combinatorial therapeutics for small RNAs shows promise in treating cancers. Dr. Calin is the Principal Investigator at the Calin Laboratory at MD Anderson. He is currently working on all aspects of molecular biology and biomarkers with a focus on deadly cancers such as ovarian, gastric, colon, pancreatic, and cholangiocarcinoma. It has become evident in recent cancer research that the genomic complexity of cancer cells is more significant than originally assumed. For more than 30 years, the focus was on the development and testing of new gene therapy strategies involving protein-coding genes. The research done by Dr. Calin and his colleagues has led to the concept that small non-coding RNAs knowns as microRNA genes (miRNAs) are involved in the production of human tumors. His research also showed that another family of ncRNAs, ultraconserved genes (UCGs) plays a role in cancer initiation, progression, and the mechanisms of a predisposition to cancer. Looking to the future, the results of the studies of miRNAs and ncRNAs has led to the possibilities of combinatorial therapeutics that are customized for a specific cancer patient. Dr. Calin believes that there is a strong need to focus on the early diagnosis of cancer which has the potential to increase the survival of cancer patients significantly. To learn more visit: mdanderson.org/research Episode also available on Apple Podcasts: apple.co/30PvU9C

Dr. Eliot Peyster is a heart transplant surgeon at the University of Pennsylvania Cardiovascular Institute. He is a member of the primary cardiology treatment team that specializes in cardiovascular conditions. In addition to heart transplant as a tool for treating end stage heart disease, Dr. Peyster is interested in the possibilities of using tissue samples from heart biopsies to study the heart at a microscopic level. Click on play to learn: What role inflammatory mediators plays in heart disease. How heart transplants and left ventricular assist devices are being used to treat people with severe heart disease. How computer vision analysis may be used to as a screening tool for high-risk heart disease in the future. Dr. Peyster describes coronary vascular disease as a leading cause of death, a disease of aging. Ischemic myopathy is generally understood regarding what causes heart blockages and how they relate to heart failure. However, too little is known about the role genetic and environmental factors play in the development of heart disease. Grading pathology slides from the biopsies of heart transplant patients has been somewhat problematic. A current concern is the grading criteria for tissue biopsies of the heart during the first year after a heart transplant. Rarely do the pathologists agree with each other when they assign a grade to this type of biopsy. The inconsistency of grading leads to confusion, making it more difficult to conduct multicenter research. Dr. Peyster and his colleagues have found a way to digitize the pathology slides. They have programmed a Computer-Assisted Cardiac Histologic Evaluation Grader to read the slides of the tissue samples from transplant patients to further study CMD. The hope is that a preventative approach can be developed to prevent small vessel disease To learn more visit: pennmedicine.org Episode also available on Apple Podcasts: apple.co/30PvU9C

What dictates your decision to buy one type of cereal over the other? Cost? Nutritional content? Or is something else…like the colors of the packaging, or the nostalgic association you have with it from childhood? The truth is, you might not even be consciously aware of why you make the product purchases you do. But rest assured…others are studying this topic very closely. Press play to learn: How to distinguish between and understand the deep drivers vs. random factors of decision-making How to bridge the disconnect between perceptual and mathematical models of probability in product purchase decisions Whether and how to use large amounts of unstructured data in decision-making processes Amit Gandhi is a professor at the University of Pennsylvania and applied economist at Microsoft, where he specializes in industrial organization and econometrics. In simpler terms, he focuses on the use of data in economic models and decision-making processes, whether at the organization, industry, or individual level. He explains the most common deep drivers of decision-making and their impact on behavioral outcomes, but draws special attention to the 'random' factors that impact decisions, but have no real connection to deep drivers like cost and utility. "Do you want to try to design choice architectures that make those things go away, or do you recognize them as part of the human condition and build your product strategy in such a way as to accommodate them?" asks Gandhi. Most of his current research is about answering this question. Tune in for all the details, and learn more about Gandhi's work by finding him on Google Scholar. Episode also available on Apple Podcasts: apple.co/30PvU9C

How does understanding molecular evolution hold the key to significant advances in technology and preserving life? By studying it, there may even be clues to how to survive on planets other than Earth. Press play to learn: How synthesizing unnatural DNA building blocks is possible If we can test Martian geology to determine its base properties Why the "Vitamin C Gene" was integral to evolution A distinguished fellow and part of the Foundation for Applied Molecular Evolution, Steven Benner, discusses his research in molecular evolution and testing the viability of sustaining life on other planets. By understanding the basis of molecular DNA and its four natural bases, researchers can begin expanding that number to eight or even 12. This opens the possibility that various lifeforms may not have the same basis for evolution and developed using different mechanisms. By adapting to the world as the established systems were destroyed through phenomena like climate change, primates' DNA shifted and allowed the beings to evolve. This may be a similar trend to how humans will evolve to face future challenges. Visit https://primordialscoop.org to learn more. Episode also available on Apple Podcast: http://apple.co/30PvU9C

Nicholas (Nik) P. Money is a Professor and Director of the Western Program at Miami University. He has spent most of his professional career studying fungi and other microorganisms and has published several books on the topics. His new book, Nature Fast and Nature Slow, was released in the summer of 2021 and focuses on biology from a unique perspective, the timing of life. Click on play to learn: How miniscule units of time can be used to study fast mechanisms over slivers of time. Why Professor Money chose to focus his new book on the passing of time. What the prospects may be for human life extension. The subtitle of Nik Money's new book is, "How Life Works, From Fractions of a Second to Billions of Years." He captures the reader's attention with thought provoking statements about how quickly time seems to pass, shares the concept of milliseconds, and discusses nature slow which stretches out over billions of years. The book explores the timetable of the universe in ten chapters with each chapter focusing on a particular slice of time beginning with nature fast. In the first chapter, Money discusses the evolution of nematocysts and expands on the evolution of the branches of the tree of life including sea slugs, anemones, comb jellies, and flatworms. Each chapter in the book opens a new world of information on evolutionary changes over time. The author discusses specific topics such as bowhead whales, bats, and bristlecones. He is already planting the seeds of a new book that focuses on nature big and small. To learn more visit: https://themycologist.com Episode also available on Apple Podcast: http://apple.co/30PvU9C

Is someone pulling the wool over the country's eyes when it comes to the pros and cons of the inoculation? Informed consent is an important right to retain and may be the key to safely inoculating the population. Press play to learn: The number of inoculation suggested by the CDC How inoculation may have been shown to correlate with adverse side affects The social groups which are responsible for inoculation pressure Health freedom lawyer Greg Glaser shares his experience fighting for informed consent for a large population of civilians and doctors around the country, especially in the age of high-pressure inoculation. Inoculation have been an integral part of American society since the latter decades of the 1900s, regardless of whether they actually make people healthier. Unfortunately, due to the social pressure cultivated by years of high-profit marketing from the inoculation industry, the truth may not correlate with the information widely pushed in the media. The social constructs that have held inoculation status in paramount status for years now are also the same that cause the alienation and ridicule imposed by the inoculated population. However, this is reaching a fever pitch as mandatory inoculation have become increasingly popular among some political parties. Visit informedconsentdefense.org to learn more. Episode also available on Apple Podcasts: apple.co/30PvU9C

Dr. Abdul Kadir Slocum is a co-founder of Chemothermia, an oncology center in Turkey that combines conventional cancer treatments with "out-of-the-box" therapies to improve cancer treatment outcomes. Dr. Slocum began the clinic in 2010 in Turkey with two partners, Professor Bulent Berkarda, M.D., and Professor Mehmet Salih İyikesici, M.D. to treat cancer patients from around the world. Click on play to learn: What role cellular metabolism has in health. How diet, hyperthermia, and hyperbaric oxygen therapy maximise the efficacy and reduce the side effects of conventional treatments. How holistic treatments support the patient undergoing traditional cancer treatments with promising results. Dr. Slocum has been working with Dr. İyikesici and Dr. Berkarda on the development and application of conventional and unconventional cancer treatments such as oxygen therapy for cancer to support and balance the system. These supportive treatments give the patient more time to fight the disease. Therapies include metabolically supported chemotherapy, hyperthermia (local and whole body) therapy, hyperbaric oxygen therapy, and the ketogenic diet that all work synergistically with the standard conventional cancer treatments. Integrating the genetic and metabolic approaches with supportive strategies can maximise the efficacy of conventional treatments and reduce their side effects. Chemothermia claims to have one of the highest success rates in the world with their unique approach on cancer treatment. The clinic publishes their results in leading peer reviewed journals. Patients with stage 3 and stage 4 cancers can be treated at the clinic. Doctors develop personalized protocols for each patient treated at the clinic with promising results. To learn more visit: chemothermia.com Episode also available on Apple Podcasts: apple.co/30PvU9C

"This is one of the biggest stories ever," says T. Colin Campbell. What story is he talking about? The one that offers clear evidence of a safe, natural, and effective way to reverse cancer, diabetes, heart disease, and more. Tune in to discover: Whether there is a difference between the protein from pasture-fed animals and feedlot animals How taste preferences can change powerfully over a relatively short period of time Hidden sources of animal protein that you may not even know you consume Why most vegans still develop some of the same diseases as non-vegans and non-vegetarians T. Colin Campbell grew up on a farm, which meant growing up on dairy and animal meat. His doctoral dissertation was on the importance of animal protein consumption, and he even led a program in the Philippines aimed at helping malnourished children by providing them with quality animal proteins. His belief was firm, and in line with the rest of the nutritional science community: malnourishment results from inadequate amounts of quality protein from animal sources. But in reality, he encountered evidence which completely challenged this position: the Filipino children who were consuming animal protein like those in the Western world were at a higher risk of developing liver cancer. Animal studies showed the same thing: animals who consumed animal protein were more susceptible to the rapid growth of liver cancer. Campbell was faced with a dilemma: would he move forward with all the work he'd already promoted, or back up and carefully re-examine the evidence? He chose the latter, and received plenty of NIH funding to study whether animal protein really does cause cancer. The answer? An emphatic "Yes," says Campbell. He has since published extensively on the topic and even served on government policy boards. "The further I got into this story and learned so much about it—not just about animal protein itself but also about the entire medical system and the way we actually tell the public the information we tell them—the more I realized there's a serious problem here," says Campbell. Heart disease, diabetes, and cancer are just a few of the diseases that can be treated and altogether reversed through a whole foods, plant-based diet. Interested in learning more? Press play, and visit https://nutritionstudies.org/. Episode also available on Apple Podcasts: apple.co/30PvU9C

How can early detection and regular monitoring of breast health play a significant role in the severity of breast cancer? The earlier cancer can be detected, a significant possibility emerges that an early understanding can benefit the patient when treatment begins. Listen in to learn: How heterogeneity impacts various tumors If chemotherapy is contributing to tumors in specific ways How early-stage testing can save lives Professor of Medicine at Harvard Medical School and member of the Dana-Farber Cancer Institute, Kornelia Polyak, shares her research on the monitoring and preventing breast cancer. Through understanding why and when an individual gets breast cancer, better treatment techniques may become available, and prevention methods can be uncovered. In addition, through a deeper understanding of cause and early behavior, the next stages of treatment and prevention research can progress. The location of tumors and the environment within the body can play a significant part in determining the heterogeneity of cancer. This level of heterogeneity is one of the defining characteristics of how to treat and prevent tumors. For more information, visit polyaklab.dfci.harvard.edu. Episode also available on Apple Podcasts: apple.co/30PvU9C

Finally, you can take a deep breath in and relax…knowing you've also taken the lowest efficacious dose of your medicine, with less worry over adverse events. And it's all thanks to a company called TFF Pharmaceuticals. Press play to learn: What specific problem TFF technology solves in terms of drug metabolism and systemic absorption How TFF technology can be applied to the area of vaccines Whether TFF technology could be used with cannabinoids as an alternative to vaping Glenn Mattes has worked in the pharmaceutical industry for over forty years now, and for the past four years, has served as CEO of TFF Pharmaceuticals, a Thin Film Freezing technology platform that can improve the properties of drug formulation, delivery, and administration while maintaining efficacy and avoiding many adverse events associated with other drug therapies. The Thin Film Freezing technology uses flash freezing to capture pharmaceutical drugs in a highly active state and convert them into highly concentrated powders. These powders can then be put into a capsule and inhaler device, allowing for administration directly into the lungs. Since the lung is an ideal organ for drug metabolism and distribution throughout the body, lower doses of the drug can be used to achieve the same or better efficacy with lower incidence of adverse events. Other substances being formulated at TFF Pharmaceuticals can be inhaled through the nose, and in the works is a formulation that can be applied to the eyes or skin. Mattes explains the science behind this technique, including the details of how and why it works, and the specific ways in which it can be applied. Learn more at https://tffpharma.com/. Episode also available on Apple Podcast: http://apple.co/30PvU9C

"When psychiatry became wedded with the drug companies, it became very little more than a sales department of the pharmaceutical industry," says Dr. Peter Breggin. He explains the pre-wedding state, post-wedding state, the future of psychiatry, and how it's all related to the current virus situation. Tune in to discover: What a lobotomy is, how it works, and how recently it's been performed in the US Why various competing views in psychiatry have been reduced to one predominant viewpoint (and what that viewpoint is) The damaging side effects and deaths related to the vaccine for the current virus Dr. Breggin is a psychiatrist and author of over 20 books, with one of his most recent publications addressing the current virus situation and the influence of global predators. He's been involved with reform work his whole life, starting with giant volunteer projects in state mental hospitals over 60 years ago, to taking on almost all major lobotomy programs in the US since then, and to this very day, trying to tackle electroshock therapy, and what he calls "chemical lobotomies" through psychiatric drugs. Dr. Breggin is the first psychiatrist to take various issues to the courtroom, and has been in trial over 100 times. Along the way, he's been attacked and slandered by scientists, clinicians, fellow psychiatrists, and the medical-scientific establishment at large, but nonetheless remains firm in his stance against what he perceives to be unethical and even violent practices aimed at controlling humanity. In today's show, he reveals these practices in detail and explains how they are intimately tied to the current virus situation. Tune in to hear the full conversation. Visit www.wearetheprey.com to check out his latest book and learn more. Episode also available on Apple Podcasts: apple.co/30PvU9C

"All malignant diseases are derived from a normal cell in the body," says Dr. Owen O'Connor, MD, PhD. But how different are the malignant cells from the normal ones, and how hard is it to differentiate one from the other? This question is at the heart of the 'therapeutic window' problem in cancer treatment. But with new research in full swing, a solution may be within reach. Press play to learn: The four eras of cancer treatment, and where the future of cancer therapy is headed The problem of the therapeutic window and modern-day chemotherapies, and how a combination of immunotherapy and precision medicine could overcome it The function of B cells in the body; how they behave differently in malignant disease vs. autoimmune disease Dr. O'Connor is an international authority on lymphoma and drug development with over 25 years of experience in academic medicine. He is also Chief Scientific Officer at TG Therapeutics, a biotechnology company that focuses on targeting diseases related to underlying B cell dysfunction, like non-Hodgkin's lymphoma and some autoimmune diseases. B cells are a type of white blood cell that produce antibodies designed to rid the body of pathogens. In lymphoma and some autoimmune diseases, however, these normal B cells begin wildly misbehaving or proliferating rapidly. In the case of malignant disease, the goal is to inhibit the proliferation of and kill these B cells; in the case of autoimmune disease, the goal is to suppress their activity and interactions with other cells in the body. How is this accomplished? And what's wrong with most modern chemotherapies? Answering these questions leads Dr. O'Connor to discuss the meaning of the therapeutic window and two drugs that have been acquired and studied extensively by the team at TG Therapeutics. One of these drugs is an immunotherapy, and the other is a precision targeted therapy. The idea is that working together, these drugs could provide an effective treatment without the serious downsides of chemotherapies. Visit https://www.tgtherapeutics.com/ to learn more. Episode also available on Apple Podcasts: apple.co/30PvU9C

Kiana Aran, Ph.D. is an associate professor and director of the Aran Lab at Keck Institute and is also the Chief Scientific Officer at Cardea Bio. She is an electrical engineer with a driving interest in biology that has led her to combining these two seemingly unconnected fields. Her research has led to the discovery that amplification is not required for targeted DNA and gene detection. Click on play to learn: How functionalizing materials can be used in biosensing technologies and in lab-on-a-chip (LOC) systems. How linking biology directly with electronics molecular control signals can be accessed and studied. How the first DNA search engine is possible using a CRISPR-SNP-chip and graphene. Dr. Aran is interested in the integration electrical, mechanical, chemical, and bioengineering to develop new device solutions for use in clinical research. She thinks of the CRISPR chip as a microscopic robot that can be used as a genome typing tool, a kind of DNA search engine. This tool provides the ability to search through a complete genome in record time, among other things. Currently, the sensitivity of the platform is being evaluated and improved to allow for more types of research. Work is currently being conducted to assess the accuracy and efficiency of CRISPR itself. Research continues on combining the power of CRISPR in its search capabilities and the power of biology as a technology to facilitate research and new discoveries. To learn more visit: aranlab.org and cardeabio.com Episode also available on Apple Podcasts: apple.co/30PvU9C

A cure for cancer? Immunotherapy could be the key. Tune in to discover: How an antiviral response is similar to an anti-tumor response The various ways in which cancer evades the immune system Which immunotherapies can treat end-stage patients, and how they work Samantha Bucktrout is the senior director of research at Parker Institute for Cancer Immunotherapy, where she focuses on bringing curative immunotherapy for patients with cancer. She begins by explaining the basics of immunotherapy, noting that all throughout each and every day, our immune systems are at work detecting and eliminating pre-cancerous cells in the body. For patients who have developed metastasis and where the standard of care has failed, immunotherapy might provide promise. Research in immunology has led to an understanding of the ways in which cancer co-opts the body's natural ability to regulate the immune system, and thereby actively blocks it from doing its job. Equipped with this knowledge, it's possible to block the barriers put up by cancer through the use of antibodies. Immunotherapy, in some cases, can be considered to 'cure' patients who otherwise have fatal metastatic processes. Bucktrout discusses how chemotherapy affects the immune response, when it is used as the sole approach to cancer treatment as opposed to in conjunction with chemotherapy, how cancer cells may have evolved to evade the immune response, and much more. Press play to hear the full conversation and learn more at https://www.parkerici.org/. Episode also available on Apple Podcasts: apple.co/30PvU9C

"If you can't sleep, so what?" asks Annie Miller. Well, you may or may not agree, but the point she's making is that it's far better to not care about a lack of sleep than to panic about it. Press play for more of her insights and learn: How different people are responding differently to the virus-related shutdowns and re-entry into the "old" way of life Why the bed should only be for sleeping Why eight hours of sleep isn't best for everyone Annie Miller is a psychotherapist and the founder of DC Metro Sleep and Psychotherapy, a private practice in Bethesda, Maryland. Her specialties include sleep and insomnia, anxiety, trauma, and chronic pain. In today's show, she discusses how the current virus situation has been impacting people's anxiety and sleep health, and also explains her approach to helping people through these issues. In the process, she provides several tips on establishing and maintaining good sleep hygiene. Tune in for all the details and visit https://dcmetrotherapy.com/ to learn more. Episode also available on Apple Podcasts: apple.co/30PvU9C

How can Diabetes treatment be made more accessible and easy to use? By encouraging the availability of products to be all under one roof and finding less invasive treatment methods, patients can find new ease of lifestyle. Listen in to learn: The latest products coming on the market How pumps function and their limitations How algorithms assist with Diabetes treatment Ali Dianaty, the vice president of product innovation for the Diabetes Business at Medtronic, shares his work developing products to ease the burden placed on diabetes patients. In recent history, patients who have Diabetes were limited to very scarce, expensive, and painful treatment techniques. However, by innovating using machine learning, pumps, and similar therapeutic methods, the lifestyle surrounding Diabetes has changed and simplified treatment for many. With data storage and algorithms working with smartphone apps, devices may even remember meals one has consumed in the past and automatically adjust treatment. This will allow patients to build a database of normal behavior, tailoring treatment specifically to their lifestyle. To learn more, visit medtronicdiabetes.com/home. Episode also available on Apple Podcasts: apple.co/30PvU9C

How can victims of cystic fibrosis and other degenerative lung diseases be treated and even reverse? Stem cells may hold the key to a new world of treatments. Press play to learn: The genes that are responsible for the proliferation of CF How the regulation of genes can change the disease landscape Common complications of lung transplants Barry Stripp, Ph.D. and professor of medicine and director of the lung stem cell program at Cedars-Sinai Board of Governors Regenerative Medicine Institute, and John Mahoney, Ph.D., and head of the stem cell biology team at the Cystic Fibrosis Foundation Therapeutics Lab, join the podcast to share their work with lung regeneration and cystic fibrosis treatment. Cystic fibrosis, while not inherently destroying the lung, it disrupts bodily systems that allow the lung to function correctly. Due to mucus buildup after not allowing lungs to be appropriately hydrated, asphyxiation is one of the most common causes of death among CF sufferers. Since the repercussions and long-term maintenance requirements for lung transplants, they are not a viable solution for long periods. Due to this, the hope is to apply stem cell techniques and gene correction to aid in lung tissue regeneration. Visit cff.org or cedars-sinai.org to learn more. Episode also available on Apple Podcasts: apple.co/30PvU9C

Christopher Logan is an avid health and nutrition reader who is continuously searching for the next best thing in the wide world of physical culture and herbalism. He is the co-founder and CEO of Lost Empire Herbs, an online store that offers herbal medicine for men's health and herbal supplements for athletic performance. Logan has an interesting perspective on the history of snake oil in the United States and its impact on pharmaceuticals, supplements, and herbs. Click on play to learn: How the use of snake oil at the turn of the century to treat muscle strains and pain became a derogatory term in spite of some amazing health benefits. Why some drugs have been found to be ineffectual in treating conditions as approved by the FDA. How the environment tends to produce food that is tainted by pesticides and lacks micronutrients leading to unhealthy conditions. Christopher Logan discusses the philosophy of scientism as it relates to health and sickness. The United States is one of the most technologically advanced countries on the planet. In contrast, it has one of the worst birth outcomes. The long-term effects of the use of pesticides on crops grown in the United States serves as a reminder that less technology is better in terms of a healthy population. Less technology and living a more natural lifestyle appears to have a healthier impact on society. Supplements and herbs are not considered medicine in spite of the fact that they reduce or eliminate deficiencies in the human body. On the other hand, the FDA conducts intensive studies on proposed drugs and approves them even though they do not necessarily work as intended. To learn more visit: lostempireherbs.com Email: [email protected] Episode also available on Apple Podcasts: apple.co/30PvU9C

Luke Burgis is an entrepreneur by experience who worked on Wall Street for a short time before moving to California to jump into the startup world in Silicon Valley. He established four companies and experienced many successes and failures while in California. From the outside, Burgis appeared to have everything. However, he felt he was on a never-ending journey to find "something" while not really understanding what that something was. Click on play to learn: How the influences of René Girard and mimetic desire redirected Burgis' life path. What drives people to pursue systems of desire. How to juggle competing multiple tribes. How the concept of tribes may play a role in blaming others. As a successful entrepreneur, Burgis struggled with wanting one thing one day and wanting something else the next day. Dealing with conflicting wants on an ongoing basis led to Burgis stepping back to revaluate his life. As an avid reader, he studied various theories of want and the self and found a connection with René Girard's ideas on the concept of mimetic desires and what drives them. His research led him to spending three years in Italy in the quest to identify the driving forces of his life. As a student of psychology, classical philosophy, and theology, he learned to create distance to examine his true desires and distinguish the origins of his aspirations. Burgis learned how to identify various systems of desire and realized that people move in and out of those systems as their life changes over time. He wrote a book, Wanting: The Power of Mimetic Desire in Everyday Life that explores why we want what we want. This profound book shows readers how mimetic desire is present in their relationships. One of the chapters focuses on the rise of scapegoating and resulting violence that demonstrates how understanding the power of mimetic desire psychology can keep us from becoming involved in the negative behaviours of blaming others. To learn more visit: https://lukeburgis.com Twitter: @lukeburgis Episode also available on Apple Podcasts: apple.co/30PvU9C

How can CRISPR technology be viewed in perspective past regular lab use? By examining the bacteria left after genetic editing, the potential for new research emerges. Press play to learn: How the cell-free system works The unanswered questions that remain in the field How CAS-9 functions with mRNA Chase Beisel, a Group Leader (W2) at Helmholtz Institute for RNA-based Infection Research in Würzburg (Germany), discusses his research using CRISPR bacteria beyond their typical scope of work. While CRISPR is commonly used and known for manipulating DNA strings, there is actually a fascinating byproduct left behind. Using the bacteria responsible for the editing during the process, they are still viable for use after editing and can be seen as an extensive natural immune system. By watching and studying how mRNA functions within the system, there may be possibilities for new technology. By recruiting mRNA and turning them into guide RNA, the nature of how this change occurs can be uncovered and applied to other areas of study. Visit https://www.helmholtz-hiri.de/en/research/organisation/people/person/prof-chase-beisel/ to learn more.

Jianghong Min is a graduate student with the Department of Genetics at Harvard Medical School who is currently involved in genomics studies of the heritability of CRISPR-based gene drive cassettes to control specific functionalities in non-human species and their impact on genetic diseases. He is working on these projects at MIT with the Sculpting Evolution Group and Kevin Esvelt, Assistant Professor. Listen to the podcast to discover: Why trial work with CRISPR-based gene drive systems is important. What unintended consequences might result from genome editing techniques. What measures are being taken in the new CRISPR method to ensure safety in this area of science. What potential benefits are associated with manipulating heritable genes in non-human species such as mosquitos and mice. Min is working on a study involving the genetic editing of heritable genes using gene drive cassettes in a non-human genus. The study is in the exploration phase at this time. Of particular interest is the evolution of a gene drive system once it is released into the wild. How much genetic information can be included in the gene drive cassettes? How much control of the heritability of the gene drives do scientists have once the are released into the wild? Min is especially interested in discovering unintended consequences. Could these heritable changes spread into other nearby species? He believes in the precautionary principle that scientists should not intervene until all of the negative effects are known and should identify the greater impact of genetically modifying these organisms. To learn more, visit: MIT Media Lab: https://www.media.mit.edu Sculpting Evolution Group: www.sculptingevolution.org Episode also available on Apple Podcasts: apple.co/30PvU9C

"Nature, over millions of years, developed the immune system in vertebrate animals," says Martin Steegmaier. And one of those developments is the antibody—a large protein that detects and neutralizes threats to the body, like viruses and bacteria. Learn how one company is using this to tackle cancer, and discover: How the monoclonal antibody production process works The half-life of an antibody in the human body, and why it matters Methods of antibody-based treatment administration Steegmaier is head of research at MorphoSys AG, a company that's focused on antibody discovery and development, with an aim to become a leader in hematology-oncology and autoimmune disease treatment. He discusses the benefits and observed effects of antibody-based treatment for various cancers, and the key differences between the use of antibodies (large molecules) and small molecules in the treatment of cancer. He also explains the function of the most notable antibody treatments on the MorphoSys drug discovery platform, one of which was launched last July for the treatment of an aggressive type of cancer called diffuse large B-cell lymphoma. For a deep dive into the science behind antibody development and how antibodies interact with cancer cells, press play. Visit https://www.morphosys.com/ for more information. Episode also available on Apple Podcasts: apple.co/30PvU9C

How can the application of machine learning make CRISPR even more beneficial than it already is? By lowering bench time, researchers may free time to find even more beneficial advancements. Listen in to learn: The potential concerns some researchers pose How domains can serve multiple functions The function of fetal hemoglobin Hannah Spinner, a research specialist and Ph.D. candidate at Harvard, discusses her work in applying machine learning on CRISPR technologies and new CRISPR proteins. Applying machine learning techniques that have been proven to advance technologies in other fields holds promising results in increasing the efficiency of CRISPR technology. Reducing the tedious lab work required by researchers will allow new advancements in how we interact during the research process. New advancements and discoveries regarding proteins and their use in CRISPR have opened the possibilities of adding a function that was not previously available. By editing various bases on the genome, the function of CRISPR in that area has a wide array of possibilities. To learn more, search for Hannah Spinner on Twitter at @bellespinner. Episode also available on Apple Podcasts: apple.co/30PvU9C

Dr. Ana Soto is a Professor of Immunology at Tufts University who by training is a physician with a deep interest in science. She began working in labs while attending the university and eventually discovered an interest in how estrogens and hormones control the proliferation of cells in the breast, uterus, etc. Dr. Soto is currently conducting research on a new theory of cell proliferation and carcinogenesis at The Ana Soto – Carlos Sonenshein Lab at Tufts University. Click on play to learn: How this new theory of the proliferation of cancer cells contrasts with the predominant somatic mutation theory (SMT). How a related study on endocrine disruption became the focus of one of Dr. Soto's studies. What are the current theories on factors that trigger cancer. Dr. Soto and Schonnenschein have been focusing their research on the origins of carcinogenesis known as the Tissue Organization Field Theory (TOFT). While their studies involve the biomechanics of morphogenesis, SMT theorizes that mutations are central to the development of cancer. The TOFT theory suggests that the mutations are an epiphenomenon. According to Dr. Soto, all cells will proliferate and produce tissue architecture that is normal. When cancer is introduced by some mechanism, there is an alteration in the organization of cells and a tumor may begin to grow. One of the goals of their research is to identify the mechanism that results in the alteration of the organization of cells and the subsequent development of cancer tissues. Several influences may be at play in this situation: biochemical factors and their receptors; biochemical communication; the proliferation of mechanical forces, bioelectricity, and the formation of an extracelluar matrix. To learn more visit: https://sites.tufts.edu/sotosonnlab/ https://gsbs.tufts.edu/facultyResearch/faculty/soto-ana/research Episode also available on Apple Podcasts: apple.co/30PvU9C

One of the most profound questions in life is how did cells first materialize on Earth? Joana C. Xavier, Ph.D. is a scientist at University College London, bioengineer, and author who has focused her life's work on finding possible answers to that question. She has an interest in systems biology, specifically the origin, evolution, and diversity of prokaryotic cells, minimal cells and chassis cells. Examples of Dr. Xavier's work in computational biology include the analyses of the evolution of genes, species, and communities. She is also involved in large scale and integrative studies of metabolism. Press play to learn more about: The characteristics of prokaryotic cells and how they differ from eukaryotic cells. How the dynamics of hydrothermal vents may have played a role in the origins of life. How the vitamins and co-factors essential for us today played a vital role in establishing the first biochemical networks. Dr. Xavier has a keen interest in the origin and evolution of life and believes that hydrothermal vents may have been the site where the first cells appeared. The ocean floor is well protected from the ultraviolet light produced by the sun. Natural chimneys form around the hydrothermal vents that release heated fluids necessary for cell development and they create a dynamic environment that would be favourable for life to evolve. Because the focus of Dr. Xavier's research is on the possibility of the origins of life deep in the ocean, collecting samples to conduct research is extremely limited and expensive. As a computational biologist, she uses massive amounts of specific types of data collected by other scientists and researchers to conduct big data analysis to test her theories. The Earth is believed to be 4.5 billion years old which adds to the complexity of finding the origin of the first cell. Dr. Xavier believes there must be some type of necessity at the origin of the first cells that is governed by laws we do not yet understand. While it is difficult to determine exactly when life first emerged on the planet, some believe that it took place shortly after the Earth was formed. Identifying which genes are the oldest is challenging and the search continues to establish the last universal common ancestor (LUCA) which may lead to answers to the question of how cells materialized on Earth. To learn more visit: Joana C. Xavier website at https://jcxavier.org Twitter @jrcxavier Episode also available on Apple Podcasts: apple.co/30PvU9C

How can the water you drink contribute to the formation or treatment of cancer? Deuterium present in the water may play a significant role. Press play to learn: What heavy water is How deuterium factors into MRI's Where to find deuterium-depleted water Functional medicine doctor Petra Davelaar joins the podcast to discuss her research on deuterated water and how it may be a critical factor in health and cancer. Deuterium present in water and the food around us is often overlooked but plays a significant role in maintaining health and staving off potentially severe diseases. The lower the deuterium present in what is put into the body, the better it is. Despite the evidence that deuterium plays such a significant role in many different processes within the body, the medical industry continues to overlook the benefits of manipulating the levels within the body. However, drinking deuterium-depleted water and honing one's diet may be effective strategies to combat certain diseases. To learn more, visit https://drpetrad.com. Episode also available on Apple Podcasts: apple.co/30PvU9C

When you're out and about and stop for a bite to eat, what else are you putting in your body with those plastic utensils? Well…plastic. Leaching from plasticware is real, and it could be causing damage to your body. But there's a healthier, less wasteful option available--and it comes with the perk of being intentional about the way you eat. Tune in to learn: What's unique about the alchemy of brass The mechanism by which brass, copper, and sterling silver self-sanitize What products are offered by a company named Fed Twenty-five years ago, Dawn Prokop picked up a book that would eventually define the trajectory of her career. It was about a Tibetan monk who was issued a single wooden bowl to use for each and every meal. He would rinse it in the river, scrub it with sand, and let it dry in the sun before tucking it away in a special place. It was more than a routine--it was a ritual. Today, the way most people consume food couldn't be further from this. We often do it mindlessly, choosing the most convenient options and not thinking twice about using plastic utensil after plastic utensil. How can we change the way humans consume food? That was the question on Prokop's mind when she started brainstorming ideas that would eventually lead to a company called Fed. It's a company that values conscious, mindful eating that's good for people and the environment. She explains all the details of what Fed believes in, strives for, and offers. Press play to learn more, and check out https://fed.today/. Episode also available on Apple Podcasts: apple.co/30PvU9C

Beverly Mok is a graduate student in Chemistry and Chemical Biology at Harvard University. She is currently working in the complex field of genes and genomics focusing on genome editing in the David Liu Lab. She is also involved in the development of programmable tools to perform detailed and accurate modifications on the human genome. Current tools do a double-stranded break which the cell may try to resolve in a way that may not be ideal. Once the break happens, the cells resolve the break in two ways. They make repairs by insertions or deletions which is not ideal. Or they supply a template DNA that undergoes homogenous DNA repair back to the original sequence to precisely repair the DNA. Base editing is a new way of targeting and repairing faulty genes. The new genome editing techniques do not use double-strand breaks. The benefits of the base editing approach is that it facilitates precise genome editing and minimizes undesired by-products and toxicity associated with the double-strand breaks in DNA. Click on play to learn about: How CRISPR-Cas9 is used to edit parts of the genome. A new process of base editing that does not introduce double-strand breaks. How the new process achieves exquisite levels of specificity with base editing. What genetic diseases are being considered for future studies involving base editing. Mok is participating in studies to identify possible next generation biotherapeutics and genome editing techniques that have the potential to treat and possibly cure genetic diseases like Huntington's disease, blood cancers, and cystic fibrosis. She applies chemical biology strategies to genome editing to advance the capabilities and safety of genome-engineering proteins. To learn more visit: https://liugroup.us David R. Liu @davidrliu liugroup @liugroup Episode also available on Apple Podcasts: apple.co/30PvU9C

Turn lead into gold? Yes, it's possible. But according to Denys Bondar, PhD, that's beside the point. He's asking this question: can any substance be made to look like any other one? Press play to explore the meaning and implications of this and more: How much computing power you can get from shining 'bright' light on a single atom How it's possible to make one element look like another, and why it matters Whether it's possible for a computer to process information at the speed of light Bondar is an assistant professor at the Tulane University School of Science & Engineering whose most recent work has been on nonlinear optics. It's a field of study that describes the behavior of bright light (high-intensity light, like that given off by lasers) in nonlinear substances. He contrasts an explanation of this with an explanation of linear optics, which is observed when everyday light—like that from the lightbulbs in your house—interacts with materials and reflects back to the eye. Using analogies and metaphors, Bondar discusses these concepts in depth. He also dives into the history of optics, and provides three concrete ways in which nonlinear optics can be applied in the lab and commercially. These include the possibility of computation at the speed of light, and the induction of superconductivity into certain materials. Tune in for the full conversation and check out https://sse.tulane.edu/pep/faculty/bondar to learn more about his work. Episode also available on Apple Podcasts: apple.co/30PvU9C

This year marks the 100th anniversary of the discovery of insulin as a treatment for diabetes. For the past several decades, innovation in the diabetes space has reached unprecedented levels. Dr. David Kendall has been a key player in this space, and shares the latest insights and developments. Press play to learn: The key difference between glucose and glucagon What causes severe hypoglycemic events in the body How dasiglucagon works, how it can be administered, and who is a good candidate for it Dr. David Kendall is a senior global medical advisor at Zealand Pharma, a company that for decades has been committed to innovation in the peptide therapeutics space. By modifying naturally-occurring peptides—the tiny building blocks of proteins and enzymes—the team at Zealand is using them as treatments for human diseases. The primary focus is on metabolic diseases, like diabetes and certain GI diseases. For example, Zealand has created dasiglucagon, a now FDA-approved analog of naturally-occurring glucagon designed to treat episodes of severely low blood sugar, commonly known as hypoglycemia. Dr. Kendall explains the function and benefits of dasiglucagon, and when it can be used as a lifesaving measure in those with insulin-requiring diabetes and hypoglycemic events. He also discusses one of Zealand's latest projects, a bihormonal artificial pancreas system that provides insulin and counteractive glucagon to help people with the long-term management of diabetes. Tune in for all the details and visit https://www.zealandpharma.com/ to learn more.

What are the ethical limits of human genetic engineering? While there may never be a firm answer to this question, it is critically important to contemplate possible limitations. Listen in to learn: The differences between genetic selection and genetic design. The technologies that fall on either side of the divide between selection and design. How biases shape our perception of which traits are desirable and which traits are not. Françoise Baylis, University Research Professor and author of Altered Inheritance, joins the podcast to discuss the bioethics of human genetic engineering. The focus is on heritable human genome editing where it is anticipated that genetic modifications will be passed on to future generations. This prospect raises a number of challenging ethical questions likely to become increasingly important over time. Visit https://francoisebaylis.ca for more information.

How can cancer be treated differently than how many others have accepted as standard? Gene therapy may be the solution to change the course of cancer treatment. Listen in to learn: The chances of getting cancer in your lifetime How CAR-T therapy operates How genetic therapies are limited CEO of Poseida Therapeutics, Eric Ostertag, discusses his work to develop safe, single-treatment cures for cancer and other diseases. Since cancer has a genetic basis for operation, gene therapy can be even more effective than the previously used viruses or other therapeutic techniques. Immuno-oncology is the bleeding edge of cancer treatment and has shown the most promising results in solid tumors. Due to the genetic limitations of viral technology, it does not have the capacity for efficacy found in non-viral therapeutics. The next generation of CAR-T will have higher chances of not being thwarted by mutations and solid tumors. Visit poseida.com for more information. Episode also available on Apple Podcasts: apple.co/30PvU9C

How can plasmalogens lead researchers to discoveries in age-related disease? By giving clues of how various bodily functions work, they may be the missing piece of the puzzle. Press play to learn: How plasmalogens facilitate biogenesis Why low-level plasmalogens are problematic in the body How maximum lifespan can be extended CEO and founder of Prodrome Sciences, discuss his work with plasmalogens and how their function in the body facilitates necessary tasks throughout. As we age, our body begins to struggle to carry out processes that did not pose a challenge earlier in life. One of the keys to these functions is the presence of plasmalogens throughout the body to help facilitate proper pathways that are working as they should. Age-related diseases may have been found to be caused, at least in part, by the absence or deficiency in plasmalogens. Rather than treating diseases and increasing average lifespan, Prodrome Sciences focuses on the conditions in the body that lead to disease susceptibility. To learn more, visit prodromesciences.com. Episode also available on Apple Podcasts: apple.co/30PvU9C

Can the healthcare experience be made more comfortable and humanized? Research may show that seeking more holistic care may make some treatments and experiences more beneficial. Press play to learn: How more medical services can be coordinated How the healthcare consumer can play a role in their own healthcare journey The three main pillars of patient comfort in treatment Author and paramedic-turned-physician, Dr. Summer Knight, shares her work to shift the field of healthcare to a more human-focused experience that puts comfort at the forefront. The current focus of the healthcare industry is less on the comfort of the patient and more on the profitability and efficiency of the operations. While this may work from a business perspective, a more empathetic approach may be more beneficial for patients and families involved in ongoing treatment. By coordinating services and various silos of the medical field, the patient will have a better understanding of their enduring process. By focusing more heavily on patient happiness alongside health, the healthcare industry can begin to focus on treating the person and not just the ailment. To learn more, visit humanizing.healthcare. Episode also available on Apple Podcasts: apple.co/30PvU9C

As a world traveller, Nykki Hardin has learned about time-tested and proven methods to heal the body mentally and emotionally. She used the knowledge gained from her travels working with experts in foreign lands to create a nontoxic, detox program that is easy to use and produces amazing results for weight loss, metabolism, and hormone balance. Click on play to learn: What detoxing is about and how to do it the right way to maximize results and achieve health. How to improve nutrition and create new habits that can become a part of a healthy lifestyle. How 21 Cleanse works to rid the body of toxins and heavy metals to boost energy and clarity. Why 21 Cleanse is successful where other methods fail. At the age of 15, Nykki Hardin was a three-sport athlete and straight A student and learned how food affects physical performance and mental health. As a world traveller visiting India, Australia, Thailand, and other countries, she learned about the bodily harm caused by toxins and heavy metals in the environment. The knowledge Nykki obtained during her travels became the seeds of the creation of new products and the start of her current business, 21 Cleanse. Using exceptional entrepreneurship skills, she developed and delivers the highest quality, therapeutic grade herbal formulas and supplements for her clients. The 21 Cleanse program includes daily emails and a private session with Nikki at the end to ensure that the individual has a good foundation to maintain a healthy lifestyle. Hardin understands the harm caused in the body by toxic chemicals, the advantages of a plant-based diet, and the benefits of an herbal cleanse. Her education, life experiences, and enthusiasm are evident as she shares health and nutrition information. Nykki provides empowerment to those participating in 21 Cleanse and facilitates healing for depression and anxiety and the achievement of health goals. To learn more visit: nykkihardin.com therightwaytodetox.com Episode also available on Apple Podcasts: apple.co/30PvU9C

How can the body's equilibrium impact your overall health and immune system's strength? By maintaining blood chemistry balance, your body may be able to fight off disease that to which it may have been previously prone. Press play to learn: The optimal range of balance for each individual What can cause toxicity within the body How the HPAT system regulates overall health Dr. Sandy Bevacqua shares her insight into balancing blood chemistry and maintaining equilibrium within the body. If the body is not in a state of equilibrium, it will continue to function while doing significant harm to various systems throughout. Outside toxicity is also a considerable contributor to throwing the system out of balance and can be a primary cause of sickness and chronic disease. Since many of the systems rely on each other to function correctly, a shutdown or malfunction in one can cause widespread poor health in many parts of the body. As toxicity in our environments builds, it becomes increasingly important to be mindful of what we allow into our bodies. To learn more, visit drsandybevacqua.com. Episode also available on Apple Podcasts: apple.co/30PvU9C

With the help of an African Grey parrot named Alex, Irene Pepperberg, Ph.D. has conducted years of research that helped the world understand the unique and amazing communication abilities of Grey parrots. In this podcast, Dr. Pepperberg shares the results of more than four decades of her research into the cognitive and communitive capabilities of Grey parrots. Press play to learn How Dr. Pepperberg's research influenced how scientists perceive avian intelligence Why Pepperberg used the model/rival technique to train Alex About Alex's ability to identify shapes, colors, and sizes, and count objects The pros and cons of having an African grey parrot as a pet Dr. Pepperberg completed her studies in chemistry at Harvard University in the 70s. While finishing her degree, Pepperberg became interested in the use of sign language and computer interfaces and studied the available data on interspecies communication. Her ultimate objective was to establish two-way communication with a Grey parrot that was similar to ongoing efforts with chimpanzees and dolphins. An African Grey parrot named Alex joined Pepperberg in her research on animal cognition and communication skills. With training by Pepperberg, Alex developed the ability to express more than 100 vocal labels for objects, colors, and actions. He understood the concepts of materials, same and different, relative size, and absence/none. His decades of work and achievements with Dr. Pepperberg demonstrated that Grey parrots have an intellect much greater than what was originally perceived. Dr. Pepperberg believes that Alex had the intelligence of a five-year-old child and the speech abilities of an 18-month to two-year-old child. She continued to train him using a modeling technique to demonstrate to Alex the things she wanted him to learn such as counting, colors, and shapes. One person would model the desired behavior with another individual and they would exchange roles as Alex observed their interactions. They would occasionally answer a question incorrectly to demonstrate to Alex that only the right answer was acceptable. Sadly, Alex passed away unexpectedly in 2007. In the scientific world, the work done by Dr. Pepperberg has increased the awareness of bird intelligence. She continues to develop research possibilities in pitch perception and visual optic illusions. With the assistance of Griffin, an African Grey parrot who was hatched in 1995, Pepperberg plans to complete her studies on delayed gratification to add to existing data in the field of language learning of animals To learn more visit: alexfoundation.org Episode also available on Apple Podcasts: apple.co/30PvU9C

How do various CRISPR systems interact with the body in beneficial ways? Using different techniques, specific immunity systems may be targeted and cleaved. Listen up to learn: How molecules are targeted to be cleaved Why RNA helps target specific systems Where the RNA fuses onto the DNA Professor in the Department of Molecular Biology and Genetics at Cornell, Ailong Ke, shares his research working with CRISPR interference and RNA molecules. By degrading and cleaving DNA in rounds, the molecule may be repaired, and the DNA can be made to function in the intended way. By editing DNA in this way, insertions and deletions can be accomplished, and DNA can be corrected to perform in its intended role. This technique can be used to correct genetic diseases and other ailments caused by errors embedded in the DNA. As these tools and techniques advance, broader targeting abilities will become available, and deletion abilities may become more precise and effective. Visit https://scholar.google.com/citations?user=Dw2YCUcAAAAJ&hl=en for more information. Episode also available on Apple Podcasts: apple.co/30PvU9C

The aftermath can be just as challenging and uncomfortable—the aftermath of major surgery, that is. Tune in to learn about a revolutionary product that's changing the post-op lives of thousands. You'll learn: The specifics behind the robe design that enables better movement, greater comfort, and erases the risk of skin irritation from other methods of securing Jackson Pratt (JP) drains The incredible story of how the "Elliott" Superhero Robe got its name, and what makes this robe so unique About how many surgeries requiring JP drains occur in the US each year Allison Schickel is a mother, wife, mentor, speaker, and Creator/Founder/CEO of Brobe, a company that has helped tens of thousands of people feel more comfortable, secure, and independent while recovering from major operations. The company began with a focus on the needs of breast cancer survivors in the post-op phase of recovery. The Brobe is a bra and robe combination designed specifically to hold JP drains, which are used in most major surgeries to reduce post-op swelling. Since Brobe's launch in 2012, over 40,000 women have found comfort in the product after having a mastectomy. But Brobe isn't just helping women. The product has proven useful for both men and women who've undergone virtually any type of surgery, whether open heart, organ transplant, cosmetic, etc. And the most recent product is even helping children who battle cancer: the new Elliott Superhero Robe is gender-neutral, and comes with two superhero capes, an eye mask, and doctor hats. With "snap-on" pockets that can be placed in almost any location, it's designed to fit almost any set of needs that a child might face—including, of course, the need for confidence, excitement, and fun. The team at Brobe always has their ears open to customer feedback, which has been overwhelmingly positive. It has also led to a number of other products, including Jackson Pratt drain belts, comfort accessories, and cold therapy products. Tune in and visit https://thebrobe.com/ for more. Episode also available on Apple Podcasts: apple.co/30PvU9C