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The Biotech Startups Podcast

The Biotech Startups Podcast

241 episodes — Page 3 of 5

Ep 140🧬Immigrant Grit & Athletic Discipline: Building a Biotech Legacy | Bogdan Knezevic (Part 1/4)

"You have to do what you have to do to get to where you want to be, and work under the constraints you have. That means swallowing your ego and just realizing that's just the reality of it. You have to grind away if you're going to hit that success." In this episode of The Biotech Startups Podcast, Bogdan Knezevic, co-founder and CEO of Kaleidoscope, shares how his family’s escape from war-torn Serbia to Canada forged his relentless work ethic and sense of purpose. He recounts adapting to a new culture, the foundational support of family and mentors, and how his passion for science and math flourished in Canada’s diverse schools. As an elite swimmer and academic standout, Bogdan learned discipline and balance, skills that now drive his mission to make scientific research more collaborative and impactful. The conversation highlights his commitment to paying it forward by building supportive ecosystems in science and business for future generations

Apr 28, 202544 min

Ep 139🧬 Redefining Biotech: Building Enduring Value Beyond Acquisition | Rabia Khan (Part 4/4)

"If you are that person, if you feel like you can't find your box and you're off doing these random things that no one else seems to find interesting, it's okay. Embrace it. It's who you are and it's going to be your superpower someday." In this episode of The Biotech Startups Podcast, host Jon Chee sits down with Rabia Khan, founder and CEO of Serna Bio, to discuss her journey from Sensyne Health to building a data-driven biotech company pioneering RNA-targeted drug discovery. Rabia shares how she overcame scientific and operational hurdles, navigated contract research limitations, and boldly moved Serna Bio from the UK to San Francisco. She also reveals her intentional approach to company culture, frugality, and long-term impact—emphasizing her vision to create a biotech business built for enduring innovation, not just acquisition.

Apr 24, 202547 min

Ep 138🧬 Sales Skills & Resilience: Hidden Drivers of Biotech Success | Rabia Khan (Part 3/4)

"You have to be curious. You have to enjoy the problems as opposed to view them as problems. You can view them as puzzle pieces that you get to put together, which is a lot of fun." In this episode of The Biotech Startups Podcast, Rabia Khan shares the pivotal experiences that shaped her approach to biotech innovation, from her time at BenevolentAI and Sensyne Health to building and leading high-performance teams at the intersection of biology, machine learning, and clinical data. Rabia discusses the challenges of aligning scientists and engineers around a shared language, the importance of integrating platform and program development, and the cultural shifts needed to drive real innovation in drug discovery. She also reflects on the value of curiosity, risk-taking, and the lessons learned from managing major pharma partnerships and scaling teams under intense pressure.

Apr 21, 202537 min

Ep 137🧬 Rabia Khan - Serna Bio: Bridging Science & Tech—PhDs, MBAs, & Biotech Innovation (Part 2/4)

“I wish someone had told me when I was starting my PhD to sit down and say, ‘what do I want out of this?’ and [then] write it down. Because, unlike the UK, where PhDs are three years and time bound, in Canada, they are neither time bound nor three years. And so you can meander." In this episode of The Biotech Startups Podcast, Rabia Khan, founder and CEO of Serna Bio, joins host Jon Chee to reflect on her unconventional journey through academia, business, and biotech innovation. Rabia shares how her curiosity, resilience, and embracing uncertainty shaped her journey through a PhD in genetics and an MBA. She discusses the emotional challenges of working with animal models, the benefits and limits of business school for scientists, and personal struggles, including her father’s illness. She recounts early setbacks, like rejected consulting jobs, and how a cold email landed her at Meta (now part of Chan Zuckerberg Biohub). Rabia emphasizes “manufacturing serendipity,” differences between founder and employee mindsets, and lessons from her work at BenevolentAI, highlighting the importance of cross-disciplinary communication and challenging industry norms

Apr 17, 202544 min

Ep 136🧬 Rabia Khan - Serna Bio: Unraveling the Genetics of AI-Driven Drug Discovery (Part 1/4)

"I was born and raised in a developing country. I was born and raised in Pakistan. And it's very interesting when you're born in a developing country. That's your world. Right? That's all you know." In this episode of The Biotech Startups Podcast, we delve into Rabia Khan's remarkable journey from her childhood in Pakistan to founding Serna Bio, an AI-enabled drug discovery company. Rabia shares how her early experiences in a developing country, her aunt's battle with schizophrenia, and the sequencing of the human genome in 2000 sparked her passion for genetics and healthcare. She recounts how her career options were either medicine or engineering, setting her on a path that would eventually lead to pioneering work at the intersection of AI and biotechnology. Rabia describes her transition to McGill University in Montreal, facing the shock of -40°C weather with only a leather jacket while navigating life as an international student with no support system. Despite these challenges, she pursued dual interests in biology and economics, finding her first research opportunity in a schizophrenia lab where she started by pipetting water and washing dishes.

Apr 14, 202547 min

Ep 135🧬Alfredo Andere - LatchBio: Revolutionizing Biopharma Data & Mastering Enterprise Sales (Part 4/4)

"Focus and commitment to niche ideas have huge payoffs." In part four of our conversation with Alfredo Andere, co-founder of LatchBio, we explore how the company evolved from a simple workflow orchestrator into a comprehensive platform serving biopharma companies and solution providers. Alfredo shares his approach to enterprise sales, emphasizing the importance of speed, focus, and building strong relationships with customers. He also delves into his philosophy on fundraising and the pivotal role of iterative development in creating impactful biotech solutions. Alfredo reflects on the challenges and rewards of working in niche markets, explaining why deep commitment and loyalty to specific problems are essential for long-term success. Whether you’re a first-time founder or an experienced entrepreneur, this episode is packed with actionable insights on building, selling, and scaling in the biotech space.

Apr 10, 202548 min

Ep 134🧬Alfredo Andere - LatchBio: Building Biotech Data Tools to Revolutionize Life Sciences (Part 3/4)

"A lot of decisions when you're doing a startup come down to being naive enough to not know how hard it's going to be—and taking that leap of faith." In part three of our conversation with Alfredo Andere, co-founder of LatchBio, we dive into the early days of building a biotech startup from scratch. Alfredo shares how his team’s chemistry and blind faith led them to drop out of college and fully commit to solving biotech’s data infrastructure challenges. He details their rigorous market research process, which involved conducting hundreds of user interviews, and how this groundwork helped them raise an oversubscribed $5 million seed round led by Lux Capital. Alfredo also reflects on the stark contrast between cutting-edge data tools at tech giants like Google and the outdated methods still used in biotech, emphasizing the massive opportunity to revolutionize life sciences.

Apr 7, 202531 min

Ep 133🧬Alfredo Andere - LatchBio: College Friends, Biotech Beginnings & Thoughtful Persistence (Part 2/4)

🧬 The Biotech Startups Podcast is powered by Excedr—helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners.

Apr 3, 202534 min

Ep 132🧬 Alfredo Andere - LatchBio: Conquering Berkeley's EECS & Building a Global Vision (Part 1)

"I had to make a decision because I knew that if nothing changed, I was just gonna fail out of EECS. I remember EECS actually sent me a letter where they were like, 'Hey, if your GPA continues this low, you will be kicked out next semester.'" In part one of our conversation with Alfredo Andere, we delve into his journey from Mexico to the prestigious EECS program at UC Berkeley. Alfredo shares his early fascination with technology, the challenges of adapting to a new educational system, and the pivotal moments that shaped his academic and personal growth. Raised in various cities across Mexico, Alfredo's passion for technology was sparked by reading biographies of tech leaders like Steve Jobs and Elon Musk. His entrepreneurial spirit emerged early when he organized a forum that attracted high-profile speakers, including former Mexican presidents, to his all-boys Catholic high school. Despite initial struggles with calculus at Berkeley, Alfredo's determination and commitment to his studies ultimately led to his success in the competitive EECS program.

Mar 31, 202537 min

Ep 131🧬 Michael Paliotti - MilliporeSigma: Master Biotech Sales & Build High-Performance Teams (Part 4/4)

"I see myself as a player coach. I really try to do what I can to be in the trenches as much as I can. I'm out on the field." In the final part of our conversation with Michael Paliotti, we delve into his extensive experience in biotech sales and leadership. Michael shares insights on the nuances of working with different types of clients, from academia to large pharma and emerging biotech companies. He discusses his transition into management during the COVID-19 pandemic and his approach to leading and developing his team. Michael's leadership philosophy emphasizes building strong relationships, both with clients and team members. He stresses the importance of empathy, trust, and removing barriers for his team to succeed. His approach to management is rooted in his own experiences as a sales representative, allowing him to relate to his team's challenges and provide meaningful support.

Mar 27, 202530 min

Ep 130🧬 Michael Paliotti: Blending Science, Sales, and Side Hustles in Biotech (Part 3/4)

“Trust takes time—but it lasts longer than any sale.” In part three of our conversation with Michael Paliotti, we dive into his transition from field application scientist to full-time sales at MilliporeSigma. He opens up about his initial hesitation, how he overcame it, and why relationship-building—not quotas—became the foundation of his sales approach. Michael reflects on the experiences that shaped his mindset, from going the extra mile for colleagues to finding interests to genuinely connect over. For him, great sales isn’t about pushing products—it’s about solving problems, building trust, and being present. He also talks about how this philosophy led to unexpected opportunities, like launching a winery with close friends during the pandemic. What started as a casual wine-tasting class turned into a business rooted in the same values that guide his sales career. An experienced team leader, Michael emphasizes coaching through effort and empathy—encouraging his reps to focus on relationships as much as results. His story is a reminder that in biotech sales, success often comes from being helpful, human, and in it for the long haul.

Mar 24, 202541 min

Ep 129🧬 Michael Paliotti: Navigating Biotech Careers & Building Lasting Relationships (Part 2/4)

🧬 The Biotech Startups Podcast is powered by Excedr—helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners.

Mar 20, 202542 min

Ep 128🧬 Michael Paliotti: Navigating a Winding Path to Biotech Success (Part 1/4)

"Growing up in a science-driven environment influenced my trajectory, from my father's chemistry background at Kodak to my own experiences in academia and research." In part one of our conversation with Michael Paliotti, Regional Sales Director at Millipore Sigma, we explore his journey from a science-driven upbringing to his early career in research and forensics. Michael shares how his father's work as an organic chemist at Kodak influenced his path into science, his academic experiences at the University of Notre Dame and Duquesne University, and his unexpected detour into optometry school before finding his true calling in research. Michael holds a degree in biology from the University of Notre Dame and a master's degree from Duquesne University. Before joining Millipore Sigma, he honed his skills in academic research at the University of Pittsburgh, forensic science with the Pennsylvania State Police, and biotech startups.

Mar 17, 202540 min

Ep 127🧬 Stavros Papadopoulos: Transforming Data Management (Part 4/4)

In this final part of our conversation with Stavros, founder and CEO of TileDB, we explore the challenges and opportunities in transforming data management within the life sciences sector. Stavros discusses how smaller organizations often lag behind in adopting innovative solutions due to lack of awareness and reliance on existing tools, while larger companies like big pharma are more proactive in seeking advanced technologies. Stavros highlights the importance of behavioral change in technology adoption, emphasizing that companies should focus on their core competencies rather than building infrastructure. He draws parallels with AWS, which revolutionized server management by allowing companies to focus on their products rather than infrastructure. The conversation also touches on the moral obligation of life sciences companies to optimize efficiency, given the impact on human lives.

Mar 13, 202533 min

Ep 126🧬 Stavros Papadopoulos: Scaling TileDB & Revolutionizing Data Infrastructure (Part 3/4)

"We're wasting money. You're wasting money as an organization, like, hundreds of millions of dollars that can save you that money easily. But you have to start reasoning a little bit differently." In this third part of our conversation with Stavros Papadopoulos, founder and CEO of TileDB, we delve into the company's ambitious vision to revolutionize data management in the life sciences sector. Stavros shares the journey of TileDB from its inception as a highly technical solution to its current position as a potential game-changer in how organizations handle diverse data types. He discusses the challenges of selling innovative solutions to large pharmaceutical companies and the stark contrast in adoption between big pharma and smaller organizations. Stavros, with his background as a technologist from MIT, details the early days of TileDB, emphasizing the intense focus on technological innovation and performance optimization. He describes the company's evolution from a small team of highly skilled engineers to securing significant funding and attracting major customers in the life sciences sector. Throughout the conversation, Stavros highlights the philosophical aspect of TileDB's mission, stressing its potential impact on accelerating scientific discovery and ultimately saving lives.

Mar 10, 202535 min

Ep 125🧬Stavros Papadopoulos: How Serendipity Sparked TileDB's Startup Journey (Part 2/4)

"Serendipity plays a big role, but you need to chase it, man. You need to [chase it] and you need to perform. You need to deliver [on] your end of the deal." In part two of our conversation with Stavros Papadopoulos, founder of TileDB, we delve into his journey from academia to entrepreneurship. Stavros shares his experiences at MIT and Intel, and the serendipitous events that led to the founding of his company. He details the transition from working on cutting-edge database systems to identifying a market need in the life sciences sector, particularly in handling complex genomic data. Stavros's background in computer science and his work at the intersection of Intel and MIT uniquely positioned him to tackle the challenges of building a new type of database system. His journey highlights the importance of proactivity, networking, and being prepared for unexpected opportunities. He also shares valuable insights on the realities of starting a database company, including the significant funding requirements and the necessity of continuous learning.

Mar 6, 202541 min

Ep 124🧬 Stavros Papadopoulos: A Journey in Computer Science & Data Management (Part 1/4)

"If you are capable of acquiring knowledge, of applying the knowledge, and you like it, you can succeed. It doesn't matter what it is." In this episode of The Biotech Startups Podcast, we delve into Stavros Papadopoulos' transformative journey from Greece to Hong Kong, exploring his experiences as a PhD student at the Hong Kong University of Science and Technology. Stavros shares how a chance encounter on a bus and his professor's last-minute recommendation led him to pursue his doctorate in Hong Kong, a decision that would shape his career and personal life. Stavros describes Hong Kong as the "best city in the world," highlighting the perfect balance between intense academic rigor and vibrant city life. He explains how the university's unique environment, with students working late into the night and a campus integrated into the natural landscape, fostered both hard work and adventure. Stavros also touches on his research focus, which evolved from spatiotemporal databases to data security and cryptography, and how he learned valuable skills that continue to shape his career to this day.

Mar 3, 202553 min

Ep 123🧬 Becky Beattie: Scaling LaunchBio & Democratizing Biotech Entrepreneurship (Part 2/2)

"If I'm not building something, then I'm probably not going to be doing it for long. That's the fun part." In part two of our conversation with Becky Beattie, CEO of LaunchBio, we explore her journey scaling a national nonprofit dedicated to supporting early-stage life science founders. Becky shares how she transitioned from BioLabs to LaunchBio, initially joining what she jokingly calls "a lunch club," and eventually stepping into leadership during the pandemic. She details LaunchBio's evolution from local programming to a national organization connecting biotech entrepreneurs with critical resources and capital. Becky's background in both science and real estate uniquely positioned her to understand the challenges of biotech startups, particularly around shared lab spaces and ecosystem development. Her leadership at LaunchBio has focused on creating targeted connections between founders and investors while expanding into new markets and launching initiatives for underrepresented entrepreneurs.

Feb 27, 20251h 5m

Ep 122🧬 Becky Beattie: From Rural Beginnings to Building a National Biotech Network (Part 1)

In part one of our conversation with Becky Beattie, CEO of LaunchBio, we trace her unconventional path from rural San Jose pig farmer to biotech ecosystem builder. Becky shares how her early entrepreneurial grit, scientific curiosity, and business acumen converged to shape her career – including surviving a life-altering spinal injury and pioneering shared lab spaces. Becky holds dual degrees in molecular biology and business from the University of Colorado Boulder. Before leading LaunchBio, she honed her skills in life science sales (SeraCare, Eppendorf), strategic marketing (Comprendia), and real estate innovation (ROC Shared Workspace).

Feb 24, 20251h 2m

Ep 121🧬 Dr. Kate Yen: Scaling a Biotech, Running Lean, & Utilizing Translational Biology (Part 2)

“I didn’t set out to be an entrepreneur, but when I couldn’t find a company doing what I believed in, I built my own.” In part two of our conversation with Kate Yen, Founder and CEO of Auron Therapeutics, we explore her journey from leading a novel cancer therapy program at Agios to founding her own biotech company. Kate shares insights into drug development, clinical trials, and the business of biotech, highlighting the importance of translational biology, strategic partnerships, and lean operations in building a successful biotech startup. Kate earned her Ph.D. in Biological Chemistry from UCLA, where she also completed her postdoc. Before Auron, she held roles at Merck and as a UCLA professor before joining Agios Pharmaceuticals, where she led the IDH translational research team behind two FDA-approved IDH mutant inhibitors and co-led the discovery of vorasidenib, a promising glioma therapy now in clinical development.

Feb 20, 202551 min

Ep 120🧬 Kate Yen - Part 1 | From Academia to Biotech Leader | Translating Research into Cancer Therapies | Early Days at Merck & Agios

Part 1 of 2: Our guest today is Kate Yen, Founder and CEO of Auron Therapeutics. Auron Therapeutics leverages cutting-edge science and AI-powered analysis to develop next-generation cancer therapies by mapping key drivers of tumorigenesis. Kate earned her Ph.D. in Biological Chemistry from UCLA, where she also completed her postdoc. She held roles at Merck and as a UCLA professor before joining Agios Pharmaceuticals, where she led the IDH translational research team behind two FDA-approved IDH mutant inhibitors and co-led the discovery of vorasidenib, a promising glioma therapy now in clinical development. With deep expertise in preclinical and clinical research, a proven track record in advancing breakthrough therapies, and a passion for oncology, Kate’s journey and insights are invaluable.

Feb 17, 202551 min

Ep 119🧬 Oguzhan Atay - Part 2 | From Immigrant to Biotech Innovator | Battling Deportation with Nobel Laureate Support | Building a $140M Prenatal Testing Empire

Part 2 of 2: Our guest today is Oguzhan Atay, Co-founder & CEO of BillionToOne. BillionToOne is a precision diagnostics company that quantifies biology to create powerful molecular diagnostics. They work to improve disease detection by counting molecules with their proprietary molecular counting platform. They place patients at the forefront of everything they do and are currently applying their proprietary technology to non-invasive prenatal screening and liquid biopsy. Oguzhan holds a Ph.D. from Stanford in Systems Biology, where he implemented machine learning algorithms and mathematical models to solve specific problems in cellular biology and developed a data-driven mathematical framework to simplify the analysis of complex biological networks. He also has a degree in Molecular Biology from Princeton, as well as minors in Computer Science, Physics, and Applied Mathematics. Oguzhan not only combines deep technical expertise with visionary leadership, but he also has an incredibly inspirational immigrant journey, which makes this series a must-listen for first-time founders, scientists, and industry leaders alike.

Feb 13, 20251h 4m

Ep 118🧬 Oguzhan Atay - Part 1 | From Small-Town Turkey to Stanford PhD | Solving Cell Cycle Mysteries | Building a Biotech During a Global Pandemic

Part 1 of 2: Our guest today is Oguzhan Atay, Co-founder & CEO of BillionToOne. BillionToOne is a precision diagnostics company that quantifies biology to create powerful molecular diagnostics. They work to improve disease detection by counting molecules with their proprietary molecular counting platform. They place patients at the forefront of everything they do and are currently applying their proprietary technology to non-invasive prenatal screening and liquid biopsy. Oguzhan holds a Ph.D. from Stanford in Systems Biology, where he implemented machine learning algorithms and mathematical models to solve specific problems in cellular biology and developed a data-driven mathematical framework to simplify the analysis of complex biological networks. He also has a degree in Molecular Biology from Princeton, as well as minors in Computer Science, Physics, and Applied Mathematics.

Feb 10, 20251h 0m

Ep 117🧬 Parag Shah - Part 2 | Scaling a Multi-Billion Dollar Life Sciences Fund | Culture, Capital & Entrepreneurship | The K2 HealthVentures Story

Part 2 of 2: Our guest today is Parag Shah, CEO and Founding Managing Director of K2 HealthVentures. K2 HealthVentures is an alternative investment firm that provides flexible, long-term financing solutions to innovative private and public companies in the life sciences and healthcare industries. Committed to making a broader impact, K2 also donates a percentage of its profits to support underserved areas in healthcare. Before founding K2, Parag was Senior Managing Director & Group Head of the Life Sciences practice at Hercules Capital, where he led the fund’s public offering and managed over $2 billion in investments. His deep expertise in life science and healthcare financing was further shaped through key leadership roles at Comerica, Imperial Bank, and BankBoston.Parag’s academic background includes a Masters in Environmental Policy & Planning and a Bachelors in Molecular Biology from MIT, where he conducted research at the Whitehead Institute. With 25+ years of experience at the intersection of science and finance, Parag brings invaluable insights for first-time founders, investors, scientists, and industry leaders navigating the complexities of biotech funding.

Feb 6, 20251h 4m

Ep 116🧬 Parag Shah - Part 1 | Rethinking Biotech Startup Funding | Building Smarter Capital Strategies | Risk, Reward & Leadership in Investing

Part 1 of 2: Our guest today is Parag Shah, CEO and Founding Managing Director of K2 HealthVentures. K2 HealthVentures is an alternative investment firm that provides flexible, long-term financing solutions to innovative private and public companies in the life sciences and healthcare industries. Committed to making a broader impact, K2 also donates a percentage of its profits to support underserved areas in healthcare. Before founding K2, Parag was Senior Managing Director & Group Head of the Life Sciences practice at Hercules Capital, where he led the fund’s public offering and managed over $2 billion in investments. His deep expertise in life science and healthcare financing was further shaped through key leadership roles at Comerica, Imperial Bank, and BankBoston.Parag’s academic background includes a Masters in Environmental Policy & Planning and a Bachelors in Molecular Biology from MIT, where he conducted research at the Whitehead Institute. With 25+ years of experience at the intersection of science and finance, Parag brings invaluable insights for first-time founders, investors, scientists, and industry leaders navigating the complexities of biotech funding.

Feb 3, 202547 min

Ep 115🧬 Jason C. Foster - Part 2 | Manufacturing Brighter Futures | From Richmond to London: Building a Biotech Empire | Culture Eats Strategy for Breakfast

Part 2 of 2: My guest today is Jason C. Foster, CEO and Executive Director of Ori Biotech. Ori is revolutionizing Cell and Gene Therapy manufacturing through the development of its proprietary platform, IRO®. By automating and standardizing Cell and Gene Therapy manufacturing, Ori and IRO® offer scientists the tools they need to streamline development and support widespread patient access to life-saving treatments. Jason's experience prior to Ori includes more than 20 years of life science leadership in operations, sales, marketing, technology, and investing, during which he developed deep expertise in commercial strategy and a thorough understanding of healthcare markets across the UK, US, and EU.

Jan 30, 20251h 4m

Ep 114🧬 Jason C. Foster - Part 1 | From Paper Routes to Pharma | Navigating the Dot-Com Bubble | Building a $1B Addiction Medicine Business in 4 Years

Part 1 of 2: My guest today is Jason C. Foster, CEO and Executive Director of Ori Biotech. Ori is revolutionizing Cell and Gene Therapy manufacturing through the development of its proprietary platform, IRO®. By automating and standardizing Cell and Gene Therapy manufacturing, Ori and IRO® offer scientists the tools they need to streamline development and support widespread patient access to life-saving treatments. Jason's experience prior to Ori includes more than 20 years of life science leadership in operations, sales, marketing, technology, and investing, during which he developed deep expertise in commercial strategy and a thorough understanding of healthcare markets across the UK, US, and EU.

Jan 27, 202555 min

Ep 113🧬 Rafael Rosengarten - Part 4 | Lessons in Scaling a Biotech Startup | Using AI to Transform Cancer Diagnostics | The Genialis Supermodel & krasID

Part 4 of 4: My guest today is Rafael Rosengarten, CEO and Co-Founder of Genialis, the RNA biomarker company. Genialis is reimagining biomarkers for every target, drug, and patient using a combination of precision oncology, RNA, and AI. Rafael, a biomedical research veteran, combines academic excellence with industry innovation. A Dartmouth graduate with a Yale doctorate, he conducted postdoctoral research at Lawrence Berkeley National Laboratory, where he co-invented the j5 DNA assembly tool. As co-founder of the Alliance for AI in Healthcare, he advocates for responsible AI integration in medicine, drawing from his extensive background in evolution, immunology, bioengineering, and genetics.

Jan 23, 202540 min

Ep 112🧬 Rafael Rosengarten - Part 3 | Leveraging AI in Precision Medicine | How Predictive Biomarkers Transform Oncology | Lessons from Scaling a Startup

Part 3 of 4: My guest today is Rafael Rosengarten, CEO and Co-Founder of Genialis, the RNA biomarker company. Genialis is reimagining biomarkers for every target, drug, and patient using a combination of precision oncology, RNA, and AI. Rafael, a biomedical research veteran, combines academic excellence with industry innovation. A Dartmouth graduate with a Yale doctorate, he conducted postdoctoral research at Lawrence Berkeley National Laboratory, where he co-invented the j5 DNA assembly tool. As co-founder of the Alliance for AI in Healthcare, he advocates for responsible AI integration in medicine, drawing from his extensive background in evolution, immunology, bioengineering, and genetics.

Jan 20, 202532 min

Ep 111🧬 Rafael Rosengarten - Part 2 | From Marine Biology to Synthetic Biology | Building Biofuel Tools at JBEI | When Academic Labs Embrace Entrepreneurship

Part 2 of 4: My guest today is Rafael Rosengarten, CEO and Co-Founder of Genialis, the RNA biomarker company. Genialis is reimagining biomarkers for every target, drug, and patient using a combination of precision oncology, RNA, and AI. Rafael, a biomedical research veteran, combines academic excellence with industry innovation. A Dartmouth graduate with a Yale doctorate, he conducted postdoctoral research at Lawrence Berkeley National Laboratory, where he co-invented the j5 DNA assembly tool. As co-founder of the Alliance for AI in Healthcare, he advocates for responsible AI integration in medicine, drawing from his extensive background in evolution, immunology, bioengineering, and genetics.

Jan 16, 202534 min

Ep 110🧬 Rafael Rosengarten - Part 1 | From Salt Marsh to Biotech CEO | Snorkeling into Science | Choosing Marine Biology Over Cooking on a Mediterranean Yacht

Part 1 of 4: My guest today is Rafael Rosengarten, CEO and Co-Founder of Genialis, the RNA biomarker company. Genialis is reimagining biomarkers for every target, drug, and patient using a combination of precision oncology, RNA, and AI. Rafael, a biomedical research veteran, combines academic excellence with industry innovation. A Dartmouth graduate with a Yale doctorate, he conducted postdoctoral research at Lawrence Berkeley National Laboratory, where he co-invented the j5 DNA assembly tool. As co-founder of the Alliance for AI in Healthcare, he advocates for responsible AI integration in medicine, drawing from his extensive background in evolution, immunology, bioengineering, and genetics.

Jan 13, 202530 min

Ep 109🧬 Cyriac Roeding - Part 4 | Revolutionizing Cancer Detection & Therapy | Harnessing Synthetic Biology to Reshape Diagnostics | Solving Biotech’s Toughest Problems

Part 4 of 4: My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker—overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide.

Jan 9, 202537 min

Ep 108🧬Cyriac Roeding - Part 3 | Founding Shopkick During the 2008 Financial Crisis | Transforming Retail with Mobile Tech | Exploring AI’s Use in Clinical Trials & Reshaping Drug Development

Part 3 of 4: My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker—overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide. Cyriac is a serial entrepreneur and investor who has created ventures at the intersection of physical and digital worlds. He has invested in startups like OpenAI and served as CEO of Shopkick, which was acquired for $250 million. His current focus, Earli, has raised nearly $60 million from top investors. Cyriac's journey from launching his first startup at 15 to being named a World Economic Forum Tech Pioneer showcases his valuable insights into building successful startups.

Jan 6, 202532 min

Ep 107🧬 Cyriac Roeding - Part 2 | From Digital Clocks to Global Mobile Marketing | Cracking Coca-Cola's 160 Million Bottle Code | Silicon Valley's Pine-Scented Entrepreneurship | Leapfrogging Technology in the Amazon Jungle

Part 2 of 4: My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker—overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide. Cyriac is a serial entrepreneur and investor who has created ventures at the intersection of physical and digital worlds. He has invested in startups like OpenAI and served as CEO of Shopkick, which was acquired for $250 million. His current focus, Earli, has raised nearly $60 million from top investors. Cyriac's journey from launching his first startup at 15 to being named a World Economic Forum Tech Pioneer showcases his valuable insights into building successful startups.

Jan 2, 202530 min

Ep 106🧬 Cyriac Roeding - Part 1 | From Flea Market Entrepreneur to Silicon Valley CEO | Reinvention During an Exchange Year | Finding Perspective in Japanese Business Culture

Part 1 of 4: My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker - overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide. Cyriac is a serial entrepreneur and investor who has created ventures at the intersection of physical and digital worlds. He has invested in startups like OpenAI and served as CEO of Shopkick, which was acquired for $250 million. His current focus, Earli, has raised nearly $60 million from top investors. Cyriac's journey from launching his first startup at 15 to being named a World Economic Forum Tech Pioneer showcases his valuable insights into building successful startups.

Dec 30, 202437 min

Ep 105🧬 Kate Neville - Part 4 | Balancing IP Enforcement & Licensing | Leveraging Shelved Pharma Assets | Building Resilient IP Portfolios

Part 4 of 4: In this episode, Jon Chee hosts Kate Neville, PhD, Partner at Marshall Gerstein—a law firm with over 60 years of expertise in delivering sophisticated intellectual property advice and legal services to leading businesses, research institutions, universities, and entrepreneurs worldwide. Kate is an accomplished attorney with a doctoral background in microbiology and immunology who specializes in global patent prosecution and strategic management. She has over a decade of experience, and works with a wide range of clients, from biotech startups to big pharma to non-profits. Kate has been recognized as a "World's Leading Patent Practitioner" by IAM magazine since 2013, an Illinois Super Lawyer since 2018, and is included in The Best Lawyers in America© for Patent Law.

Dec 19, 202431 min

Ep 104🧬Kate Neville - Part 3 | Fundamentals of IP Strategy for Biotechs | Safeguarding Discoveries & Technology | Aligning Science with Patents | Navigating Global Patent Considerations

Part 3 of 4: In this episode, Jon Chee hosts Kate Neville, PhD, Partner at Marshall Gerstein—a law firm with over 60 years of expertise in delivering sophisticated intellectual property advice and legal services to leading businesses, research institutions, universities, and entrepreneurs worldwide. Kate is an accomplished attorney with a doctoral background in microbiology and immunology who specializes in global patent prosecution and strategic management. She has over a decade of experience, and works with a wide range of clients, from biotech startups to big pharma to non-profits. Kate has been recognized as a "World's Leading Patent Practitioner" by IAM magazine since 2013, an Illinois Super Lawyer since 2018, and is included in The Best Lawyers in America© for Patent Law.

Dec 16, 202429 min

Ep 103🧬Kate Neville - Part 2 | Navigating Law School as a Scientist | From Patent Agent to Lawyer | Thriving at the Intersection of Science & Law | Continuous Learning in Diverse Scientific Fields

Part 2 of 4: Jon Chee hosts Kate Neville, Partner at Marshall Gerstein—a law firm with over 60 years of expertise in delivering sophisticated intellectual property advice and legal services to leading businesses, research institutions, universities, and entrepreneurs worldwide. Kate, an accomplished attorney with a doctoral background in microbiology and immunology, specializes in global patent prosecution and strategic management. With over a decade of experience, she works with biotech startups, big pharma, and non-profits. Kate has been recognized as a "World's Leading Patent Practitioner" by IAM magazine since 2013, an Illinois Super Lawyer since 2018, and is included in The Best Lawyers in America© for Patent Law.

Dec 12, 202420 min

Ep 102🧬 Kate Neville - Part 1 | From Youngest of Six to Patent Law Pioneer | When Chemistry Sets Spark Scientific Careers | Leading Through Autonomy | Serendipitous Path from Lab Bench to IP Law

Part 1 of 4: Jon Chee hosts Kate Neville, Partner at Marshall Gerstein—a law firm with over 60 years of expertise in delivering sophisticated intellectual property advice and legal services to leading businesses, research institutions, universities, and entrepreneurs worldwide. Kate, an accomplished attorney with a doctoral background in microbiology and immunology, specializes in global patent prosecution and strategic management. With over a decade of experience, she works with biotech startups, big pharma, and non-profits. Kate has been recognized as a "World's Leading Patent Practitioner" by IAM magazine since 2013, an Illinois Super Lawyer since 2018, and is included in The Best Lawyers in America© for Patent Law.

Dec 9, 202428 min

Ep 101🧬 Barry Ticho - Part 4 | Founding Verve Therapeutics Over Breakfast | Gene Editing for Cardiovascular Disease | Leadership Lessons From a First-Time Founder | Stoke’s Vision for RNA-Based Medicines

Part 4 of 4: Jon Chee hosts Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, a biotech company addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines. With an MD PhD from the University of Chicago and extensive experience across academia and industry, Barry brings over two decades of expertise in clinical development. His journey includes roles as Head of Development at Moderna, Head of External R&D Innovation at Pfizer, and VP of Clinical Development at Biogen, where he's been instrumental in advancing numerous therapeutic programs across multiple disease areas. Barry's unique perspective spanning academic medicine and biotechnology innovation makes his insights invaluable for aspiring leaders in the field.

Dec 5, 202439 min

Ep 100🧬 Barry Ticho - Part 3 | Lessons From Rigorous Drug Development | Industry vs. Academic Research Standards | A Patient-Centered Approach to Clinical Trials | How RNA is Shaping Modern Medicine

Part 3 of 4: Jon Chee hosts Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, a biotech company addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines. With an MD PhD from the University of Chicago and extensive experience across academia and industry, Barry brings over two decades of expertise in clinical development. His journey includes roles as Head of Development at Moderna, Head of External R&D Innovation at Pfizer, and VP of Clinical Development at Biogen, where he's been instrumental in advancing numerous therapeutic programs across multiple disease areas. Barry's unique perspective spanning academic medicine and biotechnology innovation makes his insights invaluable for aspiring leaders in the field.

Dec 2, 202437 min

Ep 99🧬Barry Ticho - Part 2 | Zebrafish Hearts & Pediatric Cardiology | Balancing Lab Work & Clinical Practice | Navigating Academic Medicine's Challenges | The Draw of Biopharma & Translational Medicine

Part 2 of 4: Jon Chee hosts Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, a biotech company addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines. With an MD-PhD from the University of Chicago and extensive experience across academia and industry, Barry brings over two decades of expertise in clinical development. His journey includes roles as Head of Development at Moderna, Head of External R&D Innovation at Pfizer, and VP of Clinical Development at Biogen, where he's been instrumental in advancing numerous therapeutic programs across multiple disease areas. Barry's unique perspective spanning academic medicine and biotechnology innovation makes his insights invaluable for aspiring leaders in the field.

Nov 28, 202428 min

Ep 98🧬Barry Ticho - Stoke Therapeutics - Part 1 | From Family of Physicians to Vision-Driven Scientist | Barry’s MD-PhD Journey | Leadership Through Critical Thinking & Resilience | The Journey From Academia to Industry

Part 1 of 4: Jon Chee hosts Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, a biotech company addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines. With an MD-PhD from the University of Chicago and extensive experience across academia and industry, Barry brings over two decades of expertise in clinical development. His journey includes roles as Head of Development at Moderna, Head of External R&D Innovation at Pfizer, and VP of Clinical Development at Biogen, where he's been instrumental in advancing numerous therapeutic programs across multiple disease areas. Barry's unique perspective spanning academic medicine and biotechnology innovation makes his insights invaluable for aspiring leaders in the field.

Nov 25, 202437 min

Ep 97🧬Chris Moxham - Transcripta Bio - Part 4 | Partnership Strategies with Big Pharma | Balancing Science & Business | Leveraging AI in Drug Discovery | The Vision for Transcripta Bio

Part 4 of 4: Jon Chee hosts Chris Moxham, Co-Founder, CEO, and CSO of Transcripta Bio—a pioneering biotech company accelerating drug discovery to improve lives worldwide. With a PhD in Molecular and Cellular Pharmacology from Stony Brook University and over 25 years in drug discovery, Chris brings a wealth of experience. During his two-decade tenure at Eli Lilly, he advanced over 10 molecules into clinical trials across multiple therapeutic areas, spanning both small and large molecule modalities. Chris’s deep expertise and dedication to scientific innovation and team development offer invaluable insights for aspiring biotech leaders.

Nov 21, 202426 min

Ep 96🧬Chris Moxham - Transcripta Bio - Part 3 | Embracing the Startup Challenge | Mastering Science-to-Business Communication | Building a Scalable Discovery Engine | Leveraging AI & Genetics in Drug Development

Part 3 of 4: Jon Chee hosts Chris Moxham, Co-Founder, CEO, and CSO of Transcripta Bio—a pioneering biotech company accelerating drug discovery to improve lives worldwide. With a PhD in Molecular and Cellular Pharmacology from Stony Brook University and over 25 years in drug discovery, Chris brings a wealth of experience. During his two-decade tenure at Eli Lilly, he advanced over 10 molecules into clinical trials across multiple therapeutic areas, spanning both small and large molecule modalities. Chris’s deep expertise and dedication to scientific innovation and team development offer invaluable insights for aspiring biotech leaders.

Nov 18, 202425 min

Ep 95🧬Chris Moxham - Transcripta Bio - Part 2 | From Eli Lilly Recruit to NYC Lab Builder | Leading High-Stakes Drug Discovery | Pioneering Quantitative Biology | "Making the Trains Run on Time"

Part 2 of 4: Jon Chee hosts Chris Moxham, the Co-Founder, CEO, and CSO of Transcripta Bio, a pioneering biotech company charting a faster path in drug discovery to create better lives for people around the world. Chris earned his PhD in Molecular and Cellular Pharmacology at Stony Brook University and is a seasoned veteran with over 25 years of drug discovery experience, having spent two decades at Eli Lilly where he was instrumental in advancing over 10 molecules into clinical trials across multiple therapeutic areas and both small and large molecule modalities. Chris has a wealth of knowledge, and his commitment to both scientific advancement and team growth makes his insights invaluable for aspiring leaders in biotech.

Nov 14, 202429 min

Ep 94🧬Chris Moxham - Transcripta Bio - Part 1 | From Long Island to Biotech Pioneer | Cornell's Pivotal Role in Research Passion | Strategic Leap to Pharma Industry | Cultivating Effective Leadership in Science

Part 1 of 4: Jon Chee hosts Chris Moxham, the Co-Founder, CEO, and CSO of Transcripta Bio, a pioneering biotech company charting a faster path in drug discovery to create better lives for people around the world. Chris earned his PhD in Molecular and Cellular Pharmacology at Stony Brook University and is a seasoned veteran with over 25 years of drug discovery experience, having spent two decades at Eli Lilly where he was instrumental in advancing over 10 molecules into clinical trials across multiple therapeutic areas and both small and large molecule modalities. Chris has a wealth of knowledge, and his commitment to both scientific advancement and team growth makes his insights invaluable for aspiring leaders in biotech.

Nov 11, 202432 min

Ep 93🧬Michael Chen - Nuclera - Part 2 | From Grad Student to Biotech CEO | Unique Challenges Combining Science & Business | Developing Breakthrough Products | Building Partnerships with Big Pharma | Creating a Biotech GTM Strategy

Jon Chee hosts Michael Chen, the Co-Founder and CEO of Nuclera, a biotech company that focuses on bringing rapid protein access to other labs. Michael is a seasoned scientist and entrepreneur who brings a rich background and valuable insights to our podcast. Before co-founding Nuclera, Michael did extensive research as an undergrad student at both Georgia tech and Emory and eventually got his PhD in Chemistry from the University of Cambridge. He has also published nine scientific papers and worked with several leading scientists in their field.

Nov 7, 20241h 4m

Ep 92🧬Michael Chen - Nuclera - Part 1 | Influence of a Data-Driven Family | Do the Dishes in a Lab | NIH-Oxford Cambridge Scholarship Program | What Got Us Here Won’t Get Us There

Part 1 of 2: Jon Chee hosts our latest guest, Michael Chen, the Co-Founder and CEO of Nuclera, a biotech company that focuses on bringing rapid protein access to other labs. Michael is a seasoned scientist and entrepreneur who brings his rich background and insights to our podcast. Before becoming the Co-Founder of Nuclera, Michael did extensive research as an undergrad student at both Georgia tech and Emory and eventually got his Ph,D in Chemistry from the University of Cambridge. Having worked under some of the leading scientists in their field Michael also has 9 scientific publications to his name. His past experiences both at the lab bench and as a CEO make these episodes ones you don’t want to miss.

Nov 4, 202452 min

Ep 91🧬 Neela Patel - Bonum Therapeutics - Part 4 | Transitioning to Seattle Genetics & Business Development | Insights from Roche’s Acquisition | Building a Transformative Oncology Pipeline with Bonum Therapeutics

Part 4 of 4: Jon Chee hosts our latest guest, Neela Patel, Chief Business Officer at Bonum Therapeutics who are developing protein therapeutics to be used to treat a wide range of diseases. Neela is a seasoned scientist and business development executive with over 30 years of leadership experience in drug discovery and development. Before her time at Bonum Therapeutics Neela worked as the CBO at Good Therapeutics, a biotech company that develops cutting edge protein-based drugs. Her impressive career also includes pivotal roles at Seattle Genetics, AbbVie, Abbott, and Genentech. Her extensive experience as both a scientist and business person give her unique insights you won’t want to miss.

Oct 31, 202432 min