
LONGEVITY with Nathalie Niddam
447 episodes — Page 9 of 9

S1 Ep 48Biosense: Tap Into the Power of Autophagy with your Breath
Biohackers often ask: How long do I need to fast before I am in autophagy? The answers come back fast and furious and it appears that nobody can agree – 16 hours? 24 hours? 72 hours? It turns out that the answer is frustratingly: "it depends"…it depends on you, your metabolic flexibility and more…the Biosense device is here to help individuals answer this burning question for themselves. In this week's episode Nathalie talks to Jim Howard from Readout Health about the Biosense Breath Ketone Monitoring device – a revolutionary method of measuring ketones more precisely without spilling a single drop of blood! We talk about the ketones, fasting and a new feature on the Biosense App that will help users to tap into their body's innate mechanisms of repair and renewal – cellular autophagy - by honing in on their individual response. Meet This Week's Guest Jim Howard is a 27-year medtech executive focused on value creation with novel approaches to patient care. Jim came to Readout as CEO from his EIR position at venture capital firm, BioGenerator, an initial investor in Readout. He is a co-founder and initial CEO of Washington University spinout SentiAR, the first AR platform for interventional procedures, currently in clinical trials. Jim led a team of 50 as VP of Sales in CareFusion's respiratory business unit through the acquisition by Becton Dickinson in 2016. He is a board director at POC medical device company, MagBiosense, and is an active mentor to new CEO's in the St. Louis healthcare ecosystem. Jim is passionate about behavioral changes in chronic diseases, putting the healthcare in the hands of patients. He has an MBA from University of Missouri-St.Louis and remains active in collaborations with Washington University researchers. Episode Sponsor: drinkHRW: This episode is sponsored by drinkHRW.com manufacturers of the best molecular hydrogen supplements on the market. For the past 4 years I have been using molecular hydrogen tablets every single day for dozens of reasons including mitigation of oxidative stress, to support my mitochondria and metabolic health, to help me recover from my workouts. I am such a fan that I have every one of my clients using drinkHRW tablets as a foundation supplement in their stacks whether their goals are healthy aging or increased performance (or both). Check out the amazing products at drinkHRW.com and use promo code Longevity10 to get 10% off your purchase! Key Takeaways [01:14] About Jim and how he got to run this cool company… [05:13] The ketogenic diet, metabolic flexibility and IM fasting in the reversal of disease… [09:32] What is being measured when using the Biosense?... [12:20] Do the numbers on the Biosense mean the same thing for everyone?.. [15:17] Are continuous glucose monitors accurate?.. [17:52] The effect your microbiome has on your body's response to sugar… [21:21] Precision fasting, the direct way to get to autophagy… [24:14] Redox potential, the ability of the body to store less BHB over time due to your body becoming more efficient… [27:35] Precision Fast, an actual fasting wheel with precise actual levels of ketosis… [28:59] How long does it take to get into ketosis, autophagy, ect? Is it the same time for everyone?.. [33:33] Tracking metabolic flexibility and ketone production with the Biosense in order to know your individual reactions to foods and exercise so that you can modify behaviors… [36:26] The fast mimicking diet, is it good or bad?.. [45:47] What apps can you sync with Biosense?.. You can purchase the biosense at https://mybiosense.com with promo code Longevity20 to save $20! Linkage: Website: https://mybiosense.com Instagram: @mybiosense Disclaimer: This podcast and the information presented are for informational purposes only and not intended to diagnose or treat disease. Before making any changes to your nutrition or supplementation please check with your physician or health provider.

S1 Ep 47Digging Deeper into BioRegulator Peptides & how they can help the body restore proper function with Phil Micans, MS, PharmB from the IAS Group
In this week's episode, Nathalie talks with Phil Micans about bioregulator peptides; which ones to take, how long to take for, and more. He also makes the generous offer to send your bioregulator questions to Nathalie and they will do a Q & A in the future answering as many as possible! Listen up so you know what questions haven't been asked so far! Meet This Week's Guest Phil Micans, MS, PharmB - Phil Micans has qualifications (including Masters and Bachelors degrees) from the UK and the USA in Food & Vitamin Technology, Pharmacy and Biochemistry. He has been actively involved in antiaging medicine since the late 1980's and has contributed to numerous books, magazines, radio and TV shows on various subjects connected to healthy aging. Currently, he is the Editor-in-Chief of the Aging Matters™ Magazine, the Assistant Editor to the Lifespan Medicine Journal (founded by Thierry Hertoghe, M.D.) and Director to the British Longevity Society (founded by Marios Kyriazis, M.D.). He also advises the Stromboli conference on cancer and aging (founded by Walter Pierpaoli, M.D.) and the London Antiageing Conference. In 1991 he was a cofounder of the IAS Group (International Antiaging Systems), an organisation dedicated to the dissemination of preventative and regenerative medicine information and the supply of hard-to-obtain health products. Bioregulator peptides can be purchased here or at Profound-Health.com save 15% off your first purchase with promo code Longevity15 Episode Sponsor: drinkHRW This episode is sponsored by drinkHRW.com manufacturers of the best molecular hydrogen supplements on the market. For the past 4 years I have been using molecular hydrogen tablets every single day for dozens of reasons including mitigation of oxidative stress, to support my mitochondria and metabolic health, to help me recover from my workouts. I am such a fan that I have every one of my clients using drinkHRW tablets as a foundation supplement in their stacks whether their goals are healthy aging or increased performance (or both). Check out the amazing products at drinkHRW.com and use promo code Longevity10 to get 10% off your purchase! Key Takeaways [1:30] How Phil got to where he is today… [11:12] Are there peptides in vegetables like there are in meat?.. [13:37] Military secrets and medical breakthroughs… The start of many medical discoveries… [17:23] Peptide bioregulator study in Siberia and the effects on mortality and morbidity… [19:32] The pineal peptide, the little pea sized gland that runs the show… [24:51] Using the Horvath Clock for measuring biological age… Is it the best measurement?.. [29:19] Stress, the biggest factor of aging… [33:48] What bioregulators should you use and in what order?.. [37:09] Using the ovarian peptide for hormone dysregulation and estrogen dominance… [38:30] Why is estrogen dominance so common now days and what can people do about it?.. [45:19] How does the thyroid bioregulator work? Will it help convert T4 to T3?.. [48:05] TRH, is it a bioregulator?.. [59:31] Closing conversations about the less popular peptides such as the lung and bladder bioregulators… [61:02] Silica and the effects on Alzheimer's… [68:00] Does the bone marrow bioregulator have the potential to increase stem cells?.. [69:00] How often do bioregulators need to be taken to see changes?.. [71:00] Use of bioregulator peptides in Olympic gymnasts… Bioregulator peptides can be purchased at https://naturesmarvels.com save 15% off your first purchase with promo code Longevity15 Disclaimer: This podcast and the information presented are for informational purposes only and not intended to diagnose or treat disease. Before making any changes to your nutrition or supplementation please check with your physician or health provider.

S1 Ep 46Dr Bill Lawrence: Reversing Aging PART 2 Bioregulator Peptides Effect on DNA Methylation Clinical Trial
In this week's episode, (part 2 to Episode #42)... Nathalie continues her conversation with Dr. Lawrence about Russian Bioregulator peptides and the role they may play in reversing biological age in humans. They review several different studies, discuss organ regeneration as well as how precisely designed BioRegulator Peptide cycles have so far affected DNA methylation patterns in Clinical Trial participants. Meet This Week's Guest Dr. Lawrence has a Jurisprudence Degree (UCLA-Law), an MS in Psychology and a Ph.D. in Nutrition with a particular interest in Longevity. Since 1990 his focus has been on slowing and reversing human biological aging. 3 years ago he started a human clinical trial in collaboration with Dr Vladimir Khavinson from the Saint Petersburg Institute of He has developed numerous science-based protocols focused on optimal aging for health professionals and individual clients. Presently Dr. Lawrence is the administrator of two clinical studies to determine if human biological age can be reversed. NB- Dr. Lawrence's chronological age is 74. His 'biological age,' based on his telomere length is 35. To buy the Nature's Marvels Bioregulator Peptides that Dr Lawrence uses in his trial you can click here or go to Profound-Health.com and use discount code Longevity15 to save 15% off your first order Key Takeaways If possible, it is best to watch this podcast on YouTube as well so that you can see the slides. There is a slide for all the highlights. [1:04] About Dr. Lawrence and a brief overview of what was talked about last episode… [8:00] Telomerase Activation and DNA Methylation Longevity Interventions… [9:00] Theories of aging/ways to intervene in the aging process… [10:36] St. Petersburg Institute of Bioregulation and Gerontology… [11:42] Vladimir Khavison, who he is and what he does… [13:30] What are peptides?... [14:00] What was the catalyst for creating bioregulator peptides? The program that created them and some of the first test subjects… [18:19] How your body uses amino acids as building blocks… [20:15] Photo of DNA and bioregulator peptide and how they fit together… [21:15] The influence of peptide bioregulators on morbidity… [24:11] Can peptide bioregulators restore retinal function?… [29:30] How are bioregulator peptides sourced?.. [29:34] Epigenetic methylation study, what methylation effects in the body and what can affect methylation… [39:05] Want to know when you are going to die?.. [44:00] How much do your genes control when it comes to health?.. [49:25] Epigenetic study on gene expression during aging… Looking at DNA age vs chronological age… [64:58] Human lifespan potential study published by the Smithsonian Magazine… [66:55] Organ regeneration with bioregulator peptides… [79:45] Can we live 150 years?.. What can we do to make that happen?.. [89:04] Do some peptides make other peptides more effective?.. [90:00] Nathalie fires off some closing questions such as are allergic reactions possible with bioregulators?… To purchase Bioregulator Peptides you can use this link https://bit.ly/BioregNN and discount code Longevity15 to save 15% off your first order! EPISODE SPONSOR: drinkHRW: For the past 4 years I have been using molecular hydrogen tablets every single day for dozens of reasons including mitigation of oxidative stress, to support my mitochondria and metabolic health, to help me recover from my workouts ....I have every one of my clients using drinkHRW tablets and they all love them too! Check out their amazing products at drinkHRW.com and use promo code Longevity10 to get 10% off your purchase! Disclaimer: This podcast and the information presented are for informational purposes only and not intended to diagnose or treat disease. Before making any changes to your nutrition or supplementation please check with your physician or health provider.

Medicinal Mushrooms with Jeff Chilton – from Nootropics to Anti Microbial Properties Medicinal Mushrooms offer a world of benefits if you know what to look for.
In this episode, Nathalie talks to Jeff Chilton about everything mushrooms. They talk about how Jeff first started his career as a mushroom picker and is now one of the leading experts in the medicinal mushroom industry. From how to tell if your mushroom supplement is actually going to do anything for you to how to cook mushrooms, the powerful medicinal properties of various mushrooms we tap into the medicinal power of these tiny but mighty foods. Meet This Week's Guest In 1973, Jeff Chilton went to work at Ostrom Mushroom Farms in Olympia Washington. Jeff quickly worked his way up to Grower and ultimately Production Manager. He followed this up with a Fellowship at the Dutch School for Mushroom Growers in 1973 that gave Jeff a much broader outlook on the mushroom industry and influenced his future path. After 10 years of commercial mushroom growing experience, Jeff co-authored and published the classic, bestselling book on small-scale mushroom cultivation, The Mushroom Cultivator. That same year he moved his family to British Columbia to start a mushroom spawn laboratory and a small speciality mushroom growing facility. In 1989 Jeff made his first trip to China to attend the International Society for Mushroom Science's (ISMS) conference in Nanjing where he discovered the depth of mushroom knowledge and production capacity that China offered. The relationships Jeff built over the next 10 years laid the foundation that made Nammex a leader in the new category of health promoting mushrooms. Nammex serves the B to B industry while Real Mushrooms, led by Skye Chilton (Jeff's son) serves the consumer with powerful supplements and extracts. To find out more about Jeff and Nammex visit https://www.nammex.com/ To purchase top quality mushroom supplements and extracts go to: https://www.realmushrooms.com/ Promo Code: Longevity15 to save 15% off your purchase Key Takeaways [02:40] About Jeff Chilton and how he became the mushroom guy... [06:26] How do you grow mushrooms?.. [12:55] Are mushrooms worth eating or should you just take a supplement?.. [17:05] How to prepare mushrooms... [20:11] What are beta glucans and how do they work?. [27:13] Mushrooms and China. Why Jeff grows mushrooms there and his experiences in China... [35:56] What is mycelium and what does it do?.. [38:48] What to look for and avoid in mushroom supplements.. [44:56] Let's talk mushrooms.. What is the difference in properties and the different applications? [56:00] What are the most popular mushrooms and how to get the most use out of them? [57:24] All about chaga, the non mushroom.. [66:11] Let's talk reishi mushrooms.. [69:22] Turkey tail, powerful enough to be a drug?.. [75:02] Dosing for reishi and turkey tail.. [78:00] Lionsmane, the ultimate nootropic? [81:09] Cordyceps for performance... [86:01] The 5 defenders mushroom blend, what it contains and why to take it... Episode Sponsor Primeadine the newest addition to my personal "foundation stack" of healthy aging supplements. Spermidine, the active ingredient in Primeadine has been shown in research to activate SIX of the 9 hallmarks of aging. Not only can it help to get younger at a cellular level but in addition the visible beauty benefits are incredible: fuller, thicker hair, better skin and stronger nails. I love this brand for its meticulous sourcing, purity of the product and zero fillers and excipients!! Use Promo Code BioNat15 to save 15% off your order! Disclaimer: This podcast and the information presented are for informational purposes only and not intended to diagnose or treat disease. Before making any changes to your nutrition or supplementation please check with your physician or health provider.

S1 Ep 44What your hair can tell you about adrenal function, thyroid function and how to correct them at a cellular level with Lisa Pitel-Killah HTMA Expert
In this week's bonus episode, Nathalie talks to Lisa Pitel-Killah about the HTMA (Hair Tissue Mineral Analysis) test and mineral imbalances. She explains the complicated relationship different minerals play and how they work off each other as well as why blood tests aren't always accurate. She covers all the basics that we sometimes forget to look at in this world of peptides, but that really are the foundation to health. Meet This Week's Guest Lisa Pitel-Killah, Hair Mineral Analysis Expert, Functional Diagnostic Practitioner and multi-time Kettlebell Sport World Champion. Lisa is also the founder of Vykon Supplements where they will custom blend supplements based on the individual's needs as determined by their HTMA results. She is also one of the founders of the HTMA Virtual Summit that is going LIVE on Monday June 7th, 2021 Lisa has a passion for guiding people to maximize health, reverse debilitating symptoms and gain energy to truly recognize their full potential. She is a health, wellness and fitness advocate, and believes that everyone should have access to the absolute best quality, all natural supplements. As she would say, "If you truly want to support your body in the best way possible, why would you use products with: subpar ingredients, or artificial flavors, sweeteners or colours? I know, I wouldn't. You can find Lisa at the virtual summit on June 7th at https://htmavirtualsummit.com/ You can also find her at https://lisapitelkillah.com or https://vykonsupps.com Promocode Nat10 gives you 10% off supplements at https://vykonsupps.com/ and your HTMA test at lisapitelkillah.com Episode Sponsor Primeadine the newest addition to my personal "foundation stack" of healthy aging supplements. Spermidine, the active ingredient in Primeadine has been shown in research to activate SIX of the 9 hallmarks of aging. Not only can it help to get younger at a cellular level but in addition the visible beauty benefits are incredible: fuller, thicker hair, better skin and stronger nails. I love this brand for its meticulous sourcing, purity of the product and zero fillers and excipients!! Use Promo Code BioNat15 to save 15% off your order! Key Takeaways [0:48] Introduction to Lisa… [04:55] What lead Lisa to where she is today… [10:33] What hair biopsies offer over other testing options such as blood… [11:50] Looking at the whole picture of mineral balance; how to understand what a true deficiency is, what really needs to be detoxed and more… [14:11] The importance of mineral ratios (zinc and copper for example)… [21:35] Explaining estrogen dominance and the causes, a common cause being copper toxicity… [29:08] Slow oxidation, what causes it and how common is it?.. [33:17] When to take binders, why to take them and what are the best binders to use?.. [41:34] GHK-cu and the effect on copper levels in the body [47:25] Signs and symptoms that your mineral balance is off… [52:50] HTMA Summit details!.. [56:00] The creation of Vykon supplements and how it makes mineral restoration protocols so much easier! Disclaimer: This podcast and the information presented are for informational purposes only and not intended to diagnose or treat disease. Before making any changes to your nutrition or supplementation please check with your physician or health provider.

S1 Ep 43Achieve Optimal Health, Performance & Aesthetics - Build From the Inside Out
In this episode, Nathalie talks to Wade Lightheart, Co-Founder of BiOptimizers nutritional supplements. As always, we start with his story, how he came to co-found Bioptimizers and then dig into some of the unique and transformative formulations that they are becoming known for. From the most complete Magnesium formula on the market to digestive enzymes and probiotics that tap into the powerful science of proteolytic enzymes…and – much much more! Meet This Week's Guest 3-Time Canadian Natural Bodybuilding Champion, Wade Lightheart, is one of the world's premier authorities on Natural Nutrition and Training Methods. Having majored in Sports Science at the University of New Brunswick, he has authored numerous books on health, nutrition and exercise which have sold in over 80 countries. Wade is sought out by athletes and high-performance oriented individuals worldwide for his advice on how to optimize their health and fitness levels. Promo Link & Code Bioptimizers.com Longevity10 to save 10% on your order!! Also! Join the FB Group: https://www.facebook.com/BiOptimizers/ Follow on Instagram: https://www.instagram.com/bioptimizers/ Follow on YouTube: https://www.youtube.com/user/BiOptimizers Key Takeaways [05:32] How did Wade get to be the bio-optimizer guy he is today?.. [09:20] Wade's experience at Mr. Universe and how "going from Mr. Universe to Mr Marshmallow" post competition drove home the importance of gut health... [16:49] Masszymes, the first product Wade developed and how they work... [19:50] Eating plant based, digestion and gut permeability... [22:50] Appropriate dosing of enzymes and how long it takes to rebuild the gut.. [25:38] The concept of The Bucket Theory of Nutrition and how it helps you focus on what to heal first... [28:38] Let's talk about digestion: how it works, IBS, constipation, gut lining and more... [31:30] Pooping yourself at the chiropractor... [37:00] The value of being " diet agnostic" when trying to decide on the best diet - from Keto to vegan, carnivore and beyond [45:22] The digestive toolkit Wade talks about all the different digestive enzymes... [52:00] P3-OM world famous patented probiotic and its many benefits... [53:41] Cognibiotics, a brain and mood enhancing probiotic!.. [55:20] Healing leaky gut with Leaky Gut Guardian; a powerful combination of IgYmax and synbiotics (probiotics and prebiotics)... [60:00] Cognitive optimization through calming down the nervous system and optimizing various neurochemical cascades by catering to the individuals needs with Nootopia….coming soon Linkage Website: Bioptimizers.com Instagram: https://www.instagram.com/bioptimizers/ Facebook: https://www.facebook.com/BiOptimizers/ YouTube: https://www.youtube.com/user/BiOptimizers

S1 Ep 42Bioregulator Peptides: Increase Health Span, Lengthen Telomeres & Turn Back the Clock with Dr. Bill Lawrence, PhD
In this episode, Nathalie talks to Dr. Bill Lawrence about the Dr. Khavinson Peptide Bioregulators and some of the jaw dropping results he has observed in the ongoing human clinical trials he started 3 years ago. The metrics being measured are Biological age as per the Horvath Clock and Telomere length. In this episode (part 1 of 2) we talk about the history of the Bioregulator Peptides, and how Dr. Lawrence came to his third (!) career as a Longevity Expert working with none other than Dr. Vladimir Khavinson. We discuss the original research published by Dr. Khavinson and finally some of the incredible results they are seeing in their test subjects (including himself and a US Olympian). Because Dr Lawrence also shares slides and photos I have also released this episode on YouTube with video – however there was one section we were not able to share to YouTube so you may want to invest the time to listen to the podcast here and then check out the video on my YouTube channel (Nathalie Niddam) to see the slides we refer to. Meet This Week's Guest Dr. Lawrence has a Jurisprudence Degree (UCLA-Law), an MS in Psychology and a Ph.D. in Nutrition. Since 1990 his focus has been on slowing and reversing human biological aging. He has developed numerous science-based protocols focused on optimal aging for health professionals and individual clients. Presently Dr. Lawrence is the administrator of two clinical studies to determine if human biological age can be reversed in collaboration with Dr Vladimir Khavinson of the Saint-Petersburg Institute of Bioregulation and Gerontology NB- Dr. Lawrence is chronologically 74 years old. His 'biological age,' based on telomere length is 35. Where to buy Nature's Marvels Bioregulator Peptides that Dr Lawrence uses in his trial you can click here or go to Profound-Health.com and use discount code Longevity15 to save 15% off your first order Note: Dr Lawrence is not affiliated with this site but these are the peptides he's used in his trial - this is an affiliate link - if you use it, thank you for your support Key Takeaways [01:48] How Dr. Lawrence got where he is today…from lawyer to entrepreneur to Longevity Expert [07:30] How did Dr. Lawrence find Dr. Khavinson's work? [19:55] What are Bioregulator peptides? How and where are they sourced? How do they work? [32:18] Aging, telomere shortening and measuring biological age [34:41] What do Russians use Bioregulator peptides for? [37:50] The effect of stress on telomere length... [41:02] The effect of Bioregulator peptides on mortality [43:41] The effect of peptides on morbidity... [45:49] The astounding results that peptides have on retinal (eye) issues including genetic diseases like Retinitis Pigmentosa [49:37] Can Bioregulator peptides possibly offer a cure for cancer? [53:17] What are telomeres and how they influence cellular aging as they shorten [56:14] Epitalon and how it induces telomerase activity and telomere elongation... [58:20 Could telomere lengthening contribute to cancer? Should cancer patients take telomere lengthening peptides? [59:58] The correlation between short telomeres and disease [61:50] Study on chronological age and telomere length. What we can do to change our telomere age.. Is stress the biggest factor? [66:54] Dr. Lawrence's telomere research on himself [73:37] Are you ever too old or too young for peptides?.. [81:08] How long can we live and how long can we live well -a discussion on healthspan and lifespan [84:17] What are the most important factors to create longevity? [88:37] The number one thing that surprised Dr. Lawrence throughout his clinical trials. Episode Sponsor: Primeadine the newest addition to my personal "foundation stack" of healthy aging supplements. Spermidine, the active ingredient in Primeadine has been shown in research to activate SIX of the 9 hallmarks of aging. Not only can it help to get younger at a cellular level but in addition the visible beauty benefits are incredible: fuller, thicker hair, better skin and stronger nails. I love this brand for its meticulous sourcing, purity of the product and zero fillers and excipients!! Use Promo Code BioNat15 to save 15% off your order! Disclaimer: This podcast and the information presented are for informational purposes only and not intended to diagnose or treat disease. Before making any changes to your nutrition or supplementation please check with your physician or health provider.

S1 Ep 41Why Weight Lifting is a Waste of Time & What to do Instead to Get The Body You Want– Dr. John Jaquish Busts Myths and Tells You How
In this episode, Nathalie talks to Dr. John Jaquish about the X3 Bar, possibly the smallest most efficient full home gym system that has helped thousands to build muscle three times faster than with weights. Dr. Jaquish's patented X3 Bar variable resistance system offers less risk of injury, easy use, portability and amazing results all in fifteen minutes a day. We talk about the science behind it, how nutrition plays into your results and lots more... Meet This Week's Guest Dr. John Jaquish, PhD. has spent years researching and developing improved approaches to health. He is the inventor of the most effective bone density building medical technology which is now partnered with Tony Robbins and OsteoStrong for rapid clinic deployment. He is also the Inventor of the X3 Bar, a technology that is proven to develop muscle much faster than conventional weight lifting, all with the lowest risk of joint injury, Dr. Jaquish methods are used in training the world's most elite athletes and associations such as the entire Miami Heat organization, various NFL and NBA players, as well as Olympians. You connect with him at https://www.jaquishbiomedical.com/doctorj/. USE this link to Save $50 http://bit.ly/BiohackX350 and promo code Save50 to save $50 off your X3 Bar! Key Takeaways [02:40] How Dr. John Jaquish got where he is today… [04:45] Take a guess what sport has the highest bone density. Hint, it's not bodybuilding… [09:27] NASA's case report on Dr. Jaquish's impact emulation devices and the positive impact they have on bone strength… [18:07] Is weightlifting a bad idea for muscle growth?.. [23:05] What exactly is the x3 system that Dr. Jaquish invented and how does it work?.. [25:50] How is it possible to get a great workout in only 10-15 min?.. [38:49] Who is a good candidate for this system? Can you be too deconditioned or too fit for X3? [45:06] Let's talk nutrition…. Fasting, carbohydrate timing and more… [55:01] Stretching for muscle growth… Linkage http://bit.ly/BiohackX350 jaquishbiomedical.com Facebook: https://www.facebook.com/drjaquish/ Instagram: @drjaquish Episode Sponsor: -drinkHRW: For the past 4 years I have been using molecular hydrogen tablets every single day for dozens of reasons including mitigation of oxidative stress, to support my mitochondria and metabolic health, to help me recover from my workouts ....I have every one of my clients using drinkHRW tablets and they all love them too! Check out their amazing products at drinkHRW.com and use promo code Longevity10 to get 10% off your purchase! Disclaimer: This podcast and the information presented is for informational purposes only and not intended to diagnose or treat disease. Before making any changes to your nutrition or supplementation please check with your physician or health provider.

S1 Ep 40Joel Greene: Slow Aging & Lose Excess Weight by Recolonizing the Gut & Rejuvenating Immunity
In this episode, Nathalie talks to Joel Greene about immune cell metabolism and how to make your body work as efficiently as possible… Weight loss without fads, crazy diets or obsessive exercise. Joel talks about his book The Immunity Code and shares some of his tips and tricks from the book. Something as simple as drinking whey protein before a meal can help your body more efficiently lose fat. Above all Joel strives for balance and bringing the body into a state of health and homeostasis so that you can slow aging and look and feel amazing! Meet this Week's Guest Joel Greene is the creator of the VEEP Nutrition System, the world's first commercially available program based on targeting gut communities to effect biomarkers, Joel also is a featured author, speaker, and guest in top tier publications like Muscle and Fitness, 24 Hour Fitness Digital Magazine, CBS Online, Superhuman Radio. His system has also been featured on the Dr. Phil Show where it has delivered astounding life-changing results. He has hacked peak human...working out once per week, eating whatever, whenever, and does it all on fast food! He is the future of real-world health and nutrition, today. To learn more about his book you can go to https://www.veepnutrition.com/ or follow him on Instagram at https://www.instagram.com/realjoelgreene. Key Takeaways [01:25] How Joel got where he is today… [6:40] Long-term effects of aggressive dieting such as fasting and keto… [11:42] What is the real cause of Crohn's? [15:15] The truth about fat. Is it the devil we think it is? [20:00] The good way vs the bad way to lose fat… [27:00] Yo-yo dieting. Why does it seem to be so common and what are the long-term effects? [31:13] Intermittent fasting good or bad… [39:41] Offsetting not avoiding. Joel talks about little things we can do to offset bad behaviors without avoiding the things we enjoy. Eat that donut. Just do good behavior with it… [52:00] How to start fixing the gut the right way. Hint probiotics is not the key.. [56:35] What are HMOs? [60:00] Can we change our genetics? [69:10] Biome testing: Good, bad or a waste of money? Linkage Website: https://www.veepnutrition.com/ Instagram: @realjoelgreene Episode Sponsor Primeadine the newest addition to my personal "foundation stack" of healthy aging supplements. Spermidine, the active ingredient in Primeadine has been shown in research to activate SIX of the 9 hallmarks of aging. Not only can it help to get younger at a cellular level but in addition the visible beauty benefits are incredible: fuller, thicker hair, better skin and stronger nails. I love this brand for its meticulous sourcing, purity of the product and zero fillers and excipients!! Use Promo Code BioNat15 to save 15% off your order! Disclaimer: This podcast and the information presented are for informational purposes only and not intended to diagnose or treat disease. Before making any changes to your nutrition or supplementation please check with your physician or health provider.

S1 Ep 39END MYOPIA – Restore your eyesight so you can THROW your glasses away
In this episode Nathalie talks to Jake Steiner about reversing myopia…that's right, actually regaining the ability to see from afar without needing glasses!! Jake stresses that he is not a medical doctor or optometrist he is simply a guy who set out to solve a problem for himself and in the process discovered some very "eye-opening" information (pun absolutely intended). He established Endmyopia.org as a resource to offer myopes the opportunity to explore science, vision biology, and optics that affect their eyesight. Jake advocates for an evidence-based approach to understanding myopia and methods to potentially reverse it. Meet This Week's Guest Jake Steiner began a journey to reverse his -5.00 diopter myopia 20 years ago. It took a great deal of experimenting and trial and error to apply theoretical concepts found in clinical journals and peer reviewed studies, though he eventually managed to get back his natural 20/20 eyesight. Over the years he cataloged the many tools, resources, and experiences that made his myopia recovery a reality and is now committed to sharing this life changing information with as many people as he can possibly reach. Key Takeaways: [01:20] Jake opens up about what lead him to his interest in eyes [01:38] Lens induced myopia [17:06] Jakes research journey [20:06] Fixing your eyesight [26:13] Measuring myopia at home [40:24] Overall health and lab work for eyes [43:56] The effect blue light and screens have on the eyes [51:21] Methods of learning more about improving eyesight [61:12] Challenging and questioning the education system Linkage: Endmyopia.org YouTube: Click Here Facebook: Endmyopia Episode Sponsor: -drinkHRW: For the past 4 years I have been using molecular hydrogen tablets every single day for dozens of reasons including mitigation of oxidative stress, to support my mitochondria and metabolic health, to help me recover from my workouts ....I have every one of my clients using drinkHRW tablets and they all love them too! Check out their amazing products at drinkHRW.com/ and use promo code Longevity10 to get 10% off your purchase! - Disclaimer: This podcast is intended for educational purposes only and is not in any way intended to provide medical advice. Please consult with your medical practitioner or health provider before making any changes to your diet, starting any new supplements or protocols.

S1 Ep 38Master Your Hormones for Vitality & Longevity with 3 Leaders Dr. Erika Schwartz, Dr. Suzanne Turner and Dr. Elizabeth Yurth
In this week's episode, three powerhouses in regenerative and functional medicine: Dr. Elizabeth Yurth, Dr. Erika Schwartz, and Dr. Suzanne Turner, join me for a jam pack session of insights on women's hormones. We take on the topic of managing hormones as they move into and through menopause. Doing so can protect your health, your vitality, your longevity, your mood as well as how you look and feel. We talk about bio-identical hormone replacement therapy and bust some of the harmful myths that have been perpetuated about it. Whether you are a woman going through this important transition yourself or, have someone in your life who is, you owe it to yourself and the people around you to get educated about this. Meet this week's guests: All three of this week's guests are Fellows of Dr. Seeds SSRP Mastermind. Dr. Elizabeth Yurth MD is the Co-Founder and Medical Director of Boulder Longevity Institute. Along with her 25-plus years as a practicing orthopedist specializing in sports, spine, and regenerative medicine, Dr. Yurth is double-Board Certified in Physical Medicine & Rehabilitation and Anti-Aging/Regenerative Medicine. She is also part of the first cohort of providers to receive the A4M National Peptide Certification. Dr. Erika Schwartz MD is the founder of ES Health takes the best of conventional and integrative medicine and applies them to preventing disease. She was one of the first doctors in the US to treat patients with bio-identical hormones, conduct biomarker testing, and to administer preventative IVs. Dr. Erika has authored six best selling books for the public along with medical articles and numerous blogs, YouTube channel and bylined articles in the highest circulation publications of the world. Dr. Suzanne Turner MD is the founder of Vine Medical Associates. She is double Board Certified in Family Medicine and AntiAging and Regenerative Medicine. Practicing Functional Medicine, Dr. Turner is an industry expert and speaker on bioidentical hormone therapy, metabolic medicine, neurodegenerative disease, and human performance optimization. She has earned Advanced Certification in Endocrinology and Peptide Therapy and is the leading expert in peptide therapy in the Southeast. Key Highlights: [02:33] People need hormones not just for the youthful looking but also for greater health [06:18] Hormones produce better in sleep, which in turn will help to support healthy testosterone and progesterone levels [09:57] Differences of each hormones and their roles [13:20] The benefits of Exercising after a meal [15:36] The difference between synthetic and bioidentical hormones [23:33] The downsides of Birth control on hormones which can affect sexual satisfaction [27:09] Three different pathways which are largely genetic based on some cytochrome pathways and a lot environmental as well [36:28] Athletic type persons have more estrogen than others [41:35] When is the best time to start hormone replacement therapy? [45:25] Strategies in obtaining growth hormones and how it helps the cells to improve the energy production of every cell Connect: Dr. Yurth's website Dr. Schwartz's website Dr. Turner's website Instagram: Dr. Yurth's: @dryurth Dr. Schwartz: @drerika218 Dr Turner: @DrSturner Disclaimer: This podcast is intended for educational purposes only and is not in any way intended to provide medical advice. Please consult with your medical practitioner or health provider before making any changes to your diet, starting any new supplements or protocols.

S1 Ep 37MyVitalC C60: Improve Focus, Energy, Sleep and Vitality with Chris Burres
In this episode, Chris Burres shares how he went from carbon nanomaterial engineer to supplement manufacturer when he and his partners launched MyVitalC - an offshoot of ESS60 that manufactures Carbon60 as a health & longevity supplement for humans and pets. C60 first got health enthusiasts' attention when toxicity trials were published that showed that C60 extended the lifespan of Wister Rats by a shocking 90 percent! While there is still much to be learned about this amazing molecule all arrows point to it acting as a powerful anti-oxidant compound with myriad downstream health benefits. Meet this week's guest: Chris Burres is a research engineer and scientist whose primary mission is to help people live longer, healthier, pain-free lives. Burres has a diverse background in the field of inventions and manufacturing. With a BS in Mechanical Engineering from University of Houston, Burres is a co-inventor of patents related to the use of explosives in downhole oil well drilling, a co-inventor of the most efficient fullerene manufacturing equipment in use since 1991, and co-owner of a company that manufactures a unique product containing a Nobel-Prize winning molecule that has been shown to extend the lifespan of test subjects by 90 percent. To try MyVitalC for yourself go to MyVitalC.com/BSPNN and use Promo code BSPNN to save $15 off your first purchase. Key Highlights: [03:53] What is Carbon Nanomaterial and what's it got to do with ESS60? [7:28] Toxicity studies shockingly showed that consumption of C60 which was expected to be toxic actually resulted in a 90% increase in lifespan in Wister rats 9:07 The leap from industrial material to longevity supplement - how that one study caused the birth of a new longevity supplement [10:06] C60 vs. ESS60. What is the difference? C60 is specialized for industrial use while ESS60 is mainly for human consumption. [11:11] Research shown that Wister rats that are bred to develop tumours as they age were given ESS60 were able to live 90% longer without developing those tumours 14:55 The reports that started to come back from people experimenting with ESS60 [17:47] The detailed process and foundation of ESS60 20:04 How much actual ESS60 can you dissolve in Olive Oil? [21:24] What the color of your C60 product tells you about the oil that was used (MCT Oil + C60 is purple, Olive Oil + C60 is brownish). The truth about the photosensitivity of C60 in Olive Oil - discussing the study that brings up concerns about what happens to C60 in Olive Oil when exposed to light. [26:04 ] The wonders of ESS60 as based on the feedback of customers and users. [28:04] Feedbacks from the customer were reporting various benefits. When the C60 taken by the morning, users report improved focus during the day and better sleep at night. [30:52] Beware the placebo effect - no matter what the supplement! [41:30] Olive oil has great antioxidant and anti-inflammatory properties which may contribute to the benefits people are reporting [46:00] Difference of ESS60 in MCT Oil [48:15] Awareness of false advertising in the market and choosing supplements [55:03] ESS60's ability as antioxidant capacity and its limitations [01:17] Why is olive oil the best carrier oil for ESS60 Linkage: MyVitalC.com Promo Code: BSPNN to save $15 off your first order. Connect : Twitter

S1 Ep 36Integrative Peptides with Dr Kent Holtorf :Bringing Oral Peptides to the Market
In this episode, Dr Kent Holtorf and I talk about how he first found peptides and how they have transformed his health and the way he practices medicine. We then discuss the oral peptides available through Integrative peptides TB4Frag for repair and immune support, BPC 157 for repair, KPV for inflammation and CerebroPep for the brain and what's coming next…. Meet this week's guest: Kent Holtorf, M.D. is the medical director of the Holtorf Medical Group and a founder and director of the non-profit National Academy of Hypothyroidism (NAH), which is dedicated to the dissemination of new evidence-based information to doctors and patients on the diagnosis and treatment of hypothyroidism and advanced integrative diagnostic and treatment protocols. He has personally trained numerous physicians across the country in the use of bioidentical hormones, hypothyroidism, peptide therapy, stem cell therapy, complex endocrine dysfunction and innovative treatments of chronic fatigue syndrome, weight loss, fibromyalgia, and chronic infectious diseases, including Lyme and related diseases. Lyme and associated diseases have been the focus of the Holtorf Medical Group centers and have been a passion of Dr. Holtorf's for over 15 years. To try these for yourself: IntegrativePeptides.com use Promo Code Longevity10 to get 10% off Key Takeaways: 2:12 How Dr Holtorf found Integrative Medicine 4:30 His health journey through med school that led to starting National Academy of Hypothyroidism, a nonprofit thyroid association 6:42 How discovering hangover free beer led to the founding of a Beer Company 8:47 Opening up 2 centers, his stressful divorce, experiencing the difficult times 9:50 Then Dr Holtorf found peptides …. Everything changed from there 12:01 In very ill patients peptides can revive the immune system so that fewer antibiotics can get the job done 15:28 When you look at the way the body works, we think of signaling it's kind of like hormones 16:17 BPC puts the body back in homeostasis 17:25 How the thymus peptides restore balance in the immune system 24:38 The link between Autoimmune conditions and infections 26:30 They do initial panel, they can pick out who has these multisystem illness and how bad it is 28:42 Thymosin alpha 1 36:00 KPV - orally bioavailable suppresses mast cells, busts biofilms, anti candida… 39:00 How can BPC be so big a molecule and still be orally bioavailable? The rule of 5.. 42:47 BPC 157 may protect EMF'S through stabilization of cellular calcium channels 48:34 TB4 supports autophagy by supporting mitochondria 50:00 TB4 and cancer - rushing to the rescue? 54:13 CerebroPep - Integrative Peptide's oral version of Cerebrolysin 59:19 Coming soon: Peptigenic, an analgesic stem cell cream with peptides in it 1:07 Heavy Metals often don't cause issues till there's an infection involved Linkage: Dr. Richard Horowitz DNA ConneXions Peptigenic Connect: www.NAHypothyroidism.org www.HoltorfMed.com www.integratedpeptides.com (Use code LONGEVITY10 to get 10% off your purchase) Disclaimer: Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Before changing your diet or using any new supplement make sure to consult with your care provider. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

S1 Ep 35Dr Mindy Pelz, DC, MENOPAUSE IS AN EXTREME SPORT - How targeted lifestyle changes can help women through this transition with ease and grace instead of suffering
In this episode Nathalie talks to Dr Mindy Pelz about her new book - The Menopause Reset - virtually a "user's manual" on how women can reclaim power over their health by understanding and supporting their hormones. The book is fantastic - it is short and to the point and explains in detail how each woman can make simple yet powerful changes to their diet and lifestyle that will support their cycles while helping them to look, feel and perform their best. Meet this week's guest: Dr. Mindy Pelz, D.C is a best selling author, keynote speaker, nutrition and functional medicine expert who has spent over two decades helping thousands of people successfully reclaim their health. She is a recognized leader in the alternative health field and a pioneer in the fasting movement, teaching the principles of a fasting lifestyle, diet variation, detox, hormones, and more. Her popular YouTube channel combines the latest science with practical lifestyle tools every person can use to reset their health. She is the host of one of the leading science podcasts, The Resetter Podcast, and the author of three best-selling books; The Menopause Reset, The Reset Factor, and The Reset Kitchen. Dr Pelz' transition from Chiropactor to Functional Medicine Practitioner was ultimately triggered 10 years into her career as she started to realize that people were unable to heal due to their environment. Key Takeaways: 2:19 Hitting menopause ultimately drove Dr Pelz to start digging into what exactly is happening to women in this transition and, more importantly, that finding a solution was going to have to come from her...not her doctor, not a pill. 7:10 The external influences - like makeup, processed foods, anxiety that affect women's hormonal cycles 7:46 The beauty of women's hormones….and how staying in sync with these hormones can help us to make the most of them 8:21 How something as simple as seed cycling can help to support hormonal balance 10:35 What foods to eat at different times of your cycle to support your hormones so that you can look, feel and perform your best… 11:03 Day 1-Day 10 the perfect time to fast, go Keto or push yourself a little harder. 11:41 Day 11-Day15 this is the time to BUILD muscle and support your microbiome.."bathe yourself in sauerkraut" Day 15-20 it's back to Keto, fasting etc…. 12:55 Day 20 is when you get to chill out...progesterone support is now the priority and healthy carbs are the name of the game… 13:36 How and why the Ketogenic Diet can backfire for many women 16:21 Helping women to take back their power over their health 19:49 There are two types of the energy system: sugar burner energy system and fat burner energy system 21:14 By doing sugar burner energy source should avoid preservative foods 34:19 Forty years old and above should eat more leafy foods for estrogen wealth 38:11 Doing HRT is best to complement a healthy lifestyle 45:32 Menopause has a different outlook on every other woman not like the standard perception 52:35 Oxytocin is an anabolic and major key in hormone growth 01:02:22 Dry fasting benefits will get us to deeper ketosis but should be under 24hrs fasting period only Linkage: The Menopause Reset book Master Amino acid Pattern Jason's Fung Book's Connect: Website: www.drmindypelz.com Dr Pelz YouTube channel Disclaimer: Please note that this podcast is for information purposes only. None of the content is intended as medical advice – before undertaking any new health initiative be it a change in diet, lifestyle or supplementation please consult with your medical practitioner.

S1 Ep 34Dr Amy Killen Optimizing Sexual & Skin Health
Dr Amy Killen, anti-aging and regenerative medicine physician specializes in beautifying skin and sexual rejuvenation. In this episode we talk about how she made the unlikely transition from emergency medicine to the field she is in today and the many ways that she is able to now support her patients to better overall health through the lens of improving skin and sexual health. She is Board Certified in Emergency Medicine with more than ten years of direct patient care, practicing Anti-Aging and Regenerative Medicine for more than five years and an advocate for empowering patients to look and feel their best by merging lifestyle modification, hormone optimization, personalized medicine and regenerative therapies. Meet this week's guest: Dr. Amy Killen MD is an anti-aging and regenerative physician specializing in sexual optimization and aesthetics. An international speaker, teacher, author and clinical practice owner, Dr. Killen is an outspoken advocate for empowering patients to look and feel their best by merging lifestyle modification, hormone optimization, personalized medicine, and regenerative therapies. Key Highlights: [06:19] Her discovery and interests in the field of regenerative medicine [07:24] What is PRP or Platelet-rich plasma? [10:20] Differences between stem cells and plasma [22:37] The ideal age to start taking peptides and other facial rejuvenation procedures [22:49] Different strategies to rejuvenate your face and skin [26:43] Peptides for Anti Aging and Rejuvenation [34:15] Alternative therapies for erectile dysfunction [39:57] Who is easier to treat a woman or man? [46:22] The uses and classification of supplements [47:49] Shockwave Therapy works as does PRP which helps for erectile dysfunction Linkage: PRP Shockwave Therapy Connect : Instagram Twitter Facebook Website Youtube

S1 Ep 33Osteoarthritis with Dr Elizabeth Yurth - Peptides, Treatments & Prevention
As Dr Yurth says: Osteoarthritis is not a "you've run too many miles" problem - it is a disease process that may be avoided altogether if caught early enough and treated if addressed properly. We explore the many ways that this debilitating condition can be addressed including some of the strategies that Dr Yurth uses in her clinic with her patients - we talk about peptides, addressing underlying causes and a few powerful supplements that can make a real difference. Meet this week's guest: Dr. Elizabeth Yurth, MD is the Founder and clinical director of the Boulder Longevity Institute in Boulder Colorado. Her specialties include Orthopaedic Surgery, Physical Medicine & Rehabilitation, Sports Medicine, Longevity and Regenerative Medicine. Dr. Yurth is Board Certified in Anti-Aging Medicine, has her advanced Fellowship Training in Anti-Aging Medicine, is a Member of the American Academy of Anti-Aging Medicine. She is also a faculty member of the SSRP - Seeds Scientific Research and Performance Mastermind. Key Highlights: [1:01] Why Dr. Yurth left the Orthopedic Practice she helped to Co-Found 27 Years ago [3:21] Why arthritis gets pushed to the background of chronic preventable diseases [5:44] Where senescent cells come into play in joint health [6:17] Where inflammation comes into play in the development of arthritis [7:21] A study on mice that may highlight the link between interleukin 1 Beta + the development of arthritis [9:00]Why steroids injected into an inflamed joint is a bad play for the long term [9:50] The loss of cytokines as part with the downward spiral into disability in advancing age [11:46] Why exercising remains a priority even when injured [12:46] Study on Rheumatoid Arthritis + movement vs. rest [13:10] the link between ACL reconstruction + arthritic knees and how EGCG may be able to help [14:35] Pentosan Polysulphate's place in post surgical recovery [15:30] How Pentosan Polysulphate works and on how it studies [18:20] The difference between the oral version of PP(Elmoron) and the injectible [20:39] Where to get PP and why just using veterinary products on humans may not be a great idea [21:59] AOD9604+ Pentosan Polysulphate + Hyaluronic Acid [23:41] Pentosan Polysulphate after surgery [24:06] How to offset the High levels of certain inflammatory nucleays can reduce the efficiency of stem cell treatments [28:55] Dr. Yurth on Red Light Therapy [33:58] What Dr. Yurth does to block inflammation Pentosan, EGCG, Melatonin [34:22] High dose Melatonin as an anti-inflammatory [35:52] High Dose of Melatonin for Septic Babies [37:00] Epigallocatechin (EGCG) and Spermidine for the win! [37:52] EGCG Pre workout to increase muscle growth Myostatin Follistatin. EGCG under 4 grams/day may bump liver enzymes in some people. 1 gram/day maintenance increase in disease states [39:07] Spermidine + Osteoarthritis [41:25] Some helpful info for Post Covid Recovery [43:57] Addressing Acidic States - Alka Seltzer Gold Linkage: Cytokines ACL Injury Aod 9604 Human Optimization Academy Connect with Dr. Yurth: Boulder Longevity Institute Linkedin Instagram: @dryurth

S1 Ep 32Amy Lamotte on the Anti aging Effects of Spermidine Part 2
This episode is the second of a two-part series on Primeadine: a new healthy aging Spermidine supplement that is already getting rave reviews. Spermidine is a potent polyamine, known for inducing autophagy or cellular renewal. As we age, our bodies are getting slower and slower in the production of spermidine leaving us more reliant on exogenous sources be they food or supplementation. Supplementation with spermidine in humans has been shown to support cognition and heart health, balance hormones and improve hair growth and fullness (including eyelashes), strengthening nails. Spermidine also positively impacts five of the nine hallmarks of aging including: misfolded proteins (impaired proteostasis), epigenetic changes, mitochondrial dysfunction, stem cell dysfunction, impaired cellular communication. Amy Lamotte is a fellow biohacker and in this episode, she shares her amazing hacks and simple and effective techniques that anyone can follow. We talk about the benefits of Spermidine, its mechanisms, and how it induces autophagy. She also shares about how she hacked her autoimmune disease, treating it and reversing it herself through diet, supplementation and testing. You shouldn't miss this episode. Listen in! Meet this week's guest: Amy Lamotte is the Managing Director of Vallotte Nutrigenomics Limited in Hong Kong. She is a clinical nutritionist and researcher specializing in personalized nutrition, nutritional biochemistry, nutrigenetics, and nutrigenomics. Other areas of interest include anti-aging, circadian biology, and the microbiome. She has a Master's of Science in Human Nutrition (summa cum laude) from the University of Bridgeport and a J.D. from Yale Law School. Key Highlights: [13:38] The mechanisms of Spermidine [06:05] What is autophagy and why is it important? [19:41] The influence of Spermidine levels in different age groups [22:12] Different factors and theories in dysregulation of spermidine [25:07] Diet has a big effect on preventive healthcare [26:50] The two great powerful combo - diet and supplements [31:35] What are the best supplements to take and not to take? [34:53] There are two types in human studies: epidemiological studies and clinical trials [38:44] The human clinical study of spermidine and the after results Linkage: Oxford Healthspan (Use promo code BIONAT15 to save 15% off your order.) Connect with Amy: Instagram: @amylamotte Linkedin: https://www.linkedin.com/in/amy-valley-lamotte-501676111/ Website: https://www.amylamotte.com/ Promo code: Bionat15 for 15% off for your full order To Try Primeadine: Primeadine.com REFERENCES FROM PODCAST INTERVIEW: REVIEW ON DIETARY & GUT MICROBIOTA POLYAMINES Ramos-Molina, B., Queipo-Ortuño, M. I., Lambertos, A., Tinahones, F. J., & Peñafiel, R. (2019). Dietary and gut microbiota polyamines in obesity-and age-related diseases. Frontiers in nutrition, 6, 24. EPIDEMIOLOGICAL STUDIES RE SPERMIDINE/POLYAMINES Eisenberg, T., Abdellatif, M., Schroeder, S., Primessnig, U., Stekovic, S., Pendl, T., ... & Madeo, F. (2016). Cardioprotection and lifespan extension by the natural polyamine spermidine. Nature medicine, 22(12), 1428-1438. Kiechl, S., Pechlaner, R., Willeit, P., Notdurfter, M., Paulweber, B., Willeit, K., ... & Willeit, J. (2018). Higher spermidine intake is linked to lower mortality: a prospective population-based study. The American journal of clinical nutrition, 108(2), 371-380. Pucciarelli, S., Moreschini, B., Micozzi, D., De Fronzo, G. S., Carpi, F. M., Polzonetti, V., ... & Napolioni, V. (2012). Spermidine and spermine are enriched in whole blood of nona/centenarians. Rejuvenation research, 15(6), 590-595 Schwarz, C., Horn, N., Benson, G., Calzado, I. W., Wurdack, K., Pechlaner, R., ... & Flöel, A. (2020). Spermidine intake is associated with cortical thickness and hippocampal volume in older adults. NeuroImage, 221, 117132. Soda, K., Kano, Y., & Chiba, F. (2012). Food Polyamine and Cardiovascular Disease-An Epidemiological Study. Global journal of health science, 4(6), 170. HUMAN TRIALS RE SPERMIDINE Pekar, T., Bruckner, K., Pauschenwein-Frantsich, S., Gschaider, A., Oppliger, M., Willesberger, J., ... & Jarisch, R. (2020). The positive effect of spermidine in older adults suffering from dementia. Wiener klinische Wochenschrift, 1-8. Schwarz, C., Stekovic, S., Wirth, M., Benson, G., Royer, P., Sigrist, S. J., ... & Flöel, A. (2018). Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline. Aging (Albany NY), 10(1), 19. Wirth, M., Benson, G., Schwarz, C., Köbe, T., Grittner, U., Schmitz, D., ... & Flöel, A. (2018). The effect of spermidine on memory performance in older adults at risk for dementia: A randomized controlled trial. Cortex, 109, 181-188. IN VIVO STUDY RE MICROBIAL SPERMIDINE PRODUCTION & BONE Chevalier, C., Kieser, S., Çolakoğlu, M., Hadadi, N., Brun, J., Rigo, D., ... & Trajkovski, M. (2020). Warmth prevents bone loss through the gut microbiota. Cell metabolism, 3

S1 Ep 31Dr. Misak on Restoring Telomeres and Using Bioelectric Testing to Establish Human Health Status
In this episode, Dr. Misak and I talked about how bioelectric chemistry changes our bodies and how to optimize personal energy efficiency. He has developed a fascinating system to give each of his patients insight into how their body works, based on bioelectric chemistry that effectively reads the body metrics, and then conveys individual deficiencies. Let us welcome him on this podcast as he unravels the chemistry and optimization of the human body. At the end of the episode we talk about a new antiaging supplement that Dr. Misak formulated that is getting rave reviews from his patients - after 3 years of development he has launched Vi-Telometry a unique & eclectic herbal formula that supports and possibly even restores telomeres! Dr Misak generously has provided a 10% discount for listeners who want to try Vi-Telometry for themselves: BIONAT10 https://vitelometry.com/ Meet this week's guest: Darrell S.C.S. Misak, ND, RPh - Doctor of Naturopathic Medicine, Licensed Pharmacist is a father of five healthy children and the creator of VI-Telometry. After receiving his Bachelor of Science degree in Pharmacy from West Virginia University in 1992, he gained 3½ years of university hospital pharmacy experience at Duke University Medical Center. During his hospital pharmacy experience, Dr. Misak's primary focus was clinical rounding in Oncology and General Medicine. As he began to realize the pitfalls of traditional medicine and pharmacy, he started his continued search for truth in health, which directed him to naturopathic medicine. Key Highlights: 03:07 Basic principles of how the body restores itself06:11 The five phases of health 08:53 Symptoms of poor sugar regulation 10:35 Cause and effect of deficiencies 12:43 How bioelectric chemistry can read the symptoms 14:32 Dr. Misak's Youtube journey 18:21 Metrics identifying the needed nutrition 22:00 Knowing your body better 25:21 People's testimonials about Vi-Telometry Dr Misak's Longevity supplement 28:24 The ingredients in Vi-Telometry 37:00 Growing food that will nourish the body - it goes beyond adding Phosphorus, Nitrogen & Potassium to the soil 39:00 Feeding soil to create nourishing food -the difference between organic and biodynamic food Linkage: Restoration of the Human Organism through Concentration on Numbers Hyperbaric oxygen therapy VI-Telometry Carey Reams Connect with Dr Misak: Website: https://vitelometry.com/ Dr Misak: https://vitelometry.com/pages/meet-dr-misak To try the Vi-Telometry Supplement: https://vitelometry.com/ Use promo code BIONAT10 for 10% off

S1 Ep 30Shawn Wells: The Energy Formula to Unleash Your Limitless Potential
In this episode, we meet Shawn Wells, the author of The Energy Formula, his new book that covers pretty much every aspect of health optimization you can think of - from nutrition to supplementation, sleep optimization to the people you surround yourself with and, most importantly, the inner work and healing we must take on to achieve truly show up as our best selves. Shawn also shares his incredible health journey, how he came to love himself on his way to a healthy lifestyle, and the many challenges he had to overcome along the way. As a master formulator, Shawn takes us on a deep dive into choosing the right supplements that can improve health and vitality while introducing us to some little-known compounds that are sure to be game changers in metabolic health. Meet this week's guest: Shawn Wells MPH, LDN, RD, CISSN, FISSN is the world's leading nutritional biochemist and expert on Health Optimization. He has been dubbed the "World's Great Formulator" of nutritional supplements. Shawn is a popular speaker and has been featured on over 150 podcasts, in documentaries and on TV segments. He has also written for numerous magazines, blogs and websites. Key Highlights: Shawn's personal health journey and how it shaped his career choice early on. [21:39] Shawn's unique take on what Biohacking means to him [30:57 ] What's in a name - breaking down the name of Energy Formula Book [36:41 ] The After-effects of stress on our body and their different types [43:10] Resiliency in our body critical for our well being [45:29] People that are closed to you have the biggest effect on our lives and how give-and-take should manifest in every relationship [49:13 ] This is the part where we dive into the book, supplementation etc...DiHydroBerberine, L Baiba, Grains of Paradise…. Connect with Shawn Wells: Shawn Wells Shawn Wells on Instagram Buy the Book!!! https://www.energyformula.com

S1 Ep 29Physician Spotlight Series: Dr Siobhan Newman from the ER to Longevity Medicine and How Peptides Fit into the Picture
Dr Siobhan Newman is a fellow of Dr William Seed's SSRP (Seed's Scientific and Research Performance) Mastermind - a growing group of physicians specializing in practicing lifestyle and regenerative medicine using, among many other things, peptides. Dr Newman spent 20 Years as a Board-certified Emergency Room Dr. until she decided it was time to help patients actually reclaim their health and vitality. She is co-founder and Chief Medical Officer of Newman MD Lifecare in Southern California. Our conversation covers the span of her philosophy of caring for her patients and how she integrates peptides, lifestyle management and bioidentical hormone therapy to help her patients reclaim their health and vitality. Meet this week's guest: Dr. Siobhan Newman is board certified in Emergency Medicine and Family Medicine, specializes in Emergency Medicine. Dr Newman has also acquired advanced certifications in Bio-Identical Hormone Therapy and Peptide Therapy - the latter through the A4M. She is affiliated with Hollywood Presbyterian Medical Center and Good Samaritan Hospital and is Co-Founder and Chief Medical Officer at Newman MD LifeCare. Key Highlights: From Emergency Room medicine to regenerative and lifestyle practice….what made it happen? Going "back to school", learning about ways to support the body, from lifestyle to nutrition, hormones and the discovery (and study) of peptides Healing the body from the inside out The importance of symptoms over (or with testing) when assessing hormone function & balance The role of and source of toxins in inflammation and disease - addressing them through detoxification and reduced exposure Where/when do peptides fit into a protocol? Hormone replacement/optimization for people in advanced years (70's and 80's) (27:00) Dr Newman's top peptides in practice… (32:00) Optimizing the immune system with peptides.. (36:00) Using peptides in cycles and in stacks….addressing cell cycles, cellular senescence, etc. Linkage: BPC 157 Thymus alpha 1 AOD 9604 Connect with Dr Siobhan Newman: [email protected] Linkedin NewMan MD Lifecare

S1 Ep 28Biostrap Part 2: Chief Science Officer Kevin Longoria talks about the Impact of Biostrap technology
In this episode, Part 2 of the Biostrap EVO series, we get the perspective of Biostrap's Chief Science Officer - Kevin Longoria on the Biostrap technology, some of the clinical studies using it and how to apply some of the metrics to your health journey. Kevin and I continue the conversation about how the Biostrap EVO could be an essential tool for Biohackers looking for clinical grade data that they can trust. We go deeper into a new metric - arterial age and elasticity and how it may turn out to be a powerful way to assess and monitor cardiovascular health. This episode has a lot of great insights! Listen in. Meet this week's guest: Kevin Longoria is an expert in the field of Clinical Physiology with an emphasis on cardiopulmonary and nervous system-based approaches to optimizing health and athletic performance. His previous role is a Chief Science Officer (CSO) for a progressive neuroscience company. He is currently a Clinical Exercise Physiologist and the Chief Science Officer at Biostrap. To buy a Biostrap: Biostrap.com To save 10% use promo code Longevity10 Key Highlights: 01:51 How Kevin found the Biostrap and ultimately became their Chief Science Officer 03:34 Biostrap is adapting through generations 05:46 What are the limitations of Biostrap? 07:58 What are the reading specifications of Biostrap? 08:28 Understanding Arterial Age 10:20 The ideal metrics for humans 12:14 The Biostrap data checking process 15:42 The most important metrics for people 23:52 How meditation reflects data 27:13 Wearable technology and Covid research 29:16 Covid intervention 33:42 Biometrics trigger indicators 40:51 Ideal sleeping pattern routine Linkage: Patrick McCown's book, The Oxygen Circadian Pattern Photoplethysmography Connect with Kevin: Website: biostrap.com Linkedin: https://www.linkedin.com/in/kevin-longoria-2b581b164/

S1 Ep 27Biostrap EVO Part 1:The "Next Level" Wearable Built For Clinicians, Nirvana for True Biohackers
In this episode, Elias Arjan and I talk about the new edition of the Biostrap, the BiostrapEVO. I've now been using Biostrap EVO for over a month and I have to say I'm pretty impressed with the quality of the data I am getting. The BiostrapEVO along with the Shoe pod and external Heart Rate Monitor together provide one of the most advanced wearable health, activity and sleep-tracking devices on the market. The Biostrap EVO enables you to get deeper insights about your body at various points in time by providing clinical-grade data. I'm really impressed with the detailed and highly accurate data readings, exercise tracking, and recovery recommendations based on exercise, exertion, sleep quality and recovery. Another great feature of Biostrap is the heart rate monitor that provides heart rate variability, blood oxygen saturation and respiratory rate monitoring. With the upcoming release of the Heart Lab - a new feature, Biostrap EVO customers will also be able to assess and track a relatively new metric: arterial age. Listen in to the episode and discover the powerful pros of Biostrap that health hackers find game-changing. This is the first of a two-part series - in part two I talk to Kevin Longoria, Chief Science Officer at Biostrap. Meet this week's guest: Elias Arjan, is the Senior Vice President at Biostrap. As part of his executive role at Biostrap, Elias oversees the marketing, communications, and sales teams and works together with the CEO to establish strategic partnerships worldwide. As a thought-leader in the field, Elias has presented at various conferences and participated in panels across medical technology and health optimization. Elias is also the Executive Director of the LA Chapter of the Biohackers Collective, a global not-for-profit dedicated to fostering community and sharing knowledge about how to unlock the code of ultimate human potential. Key Highlights: 6:24 Elias' background from science to the arts and athletics - the amazing path that led to his current position as SVP of Biostrap today 10:45 LA Magazine's recent cover story on Biohacking - an interview with Elias and a number of other prominent Biohackers in LA...setting the record straight. 13:28 Eating disorders and OCD in biohacking is it really a thing? 14:01 Managing the spectrum between growth and comfort 19:12 What is a true measurement of our health? 22:00 the Biostrap difference from other devices 26:42 Importance of HRV data - and what actually is HRV? 29:49 Obsession in data health tracking 35:03 Variation Interval between heartbeats 38:31 Wearable technology after-effects 44:36 Possible reasons in sleep latency 53:42 Specifications of medical-grade wearables 59:00 Four key biometrics 01:12:26 Arterial age vs. chronological age 01:15:49 Biostrap as a pre-screening tool... Linkage: Heart rate variability Biohackers Collective Connect with Elias Arjan: Facebook: https://www.facebook.com/eliasarjan Website: www.biostrap.com Linkedin: https://www.linkedin.com/in/eliasarjan Get your Biostrap EVO today! Use promo code LONGEVITY10 and save 10%

S1 Ep 26Dr Nasha Winters, Dasha Maximov, Kayla Osterhoff - The PowHer Program - Redefining Women's Health Optimization
In this episode, I got the privilege to speak with three powerful and badass women who are incredibly driven into working together to fix the gap in women's health through a masterful program they created called PowHer, designed uniquely for women, by these three talented women. We talk about how finding the right partners has made this huge task remarkably effortless, how amazing their inner synergies have come together, how each of their strengths complements the other. It's just so great to see women coming together and creating something that is not built out of any amount of competition. Just ease and beauty it's truly extraordinary. Listen to the episode. Meet this week's guests: Dr. Nasha Winters A global healthcare authority and best-selling author in integrative cancer care and research consulting with physicians around the world. She has educated hundreds of professionals in the clinical use of mistletoe and has created robust educational programs for both healthcare institutions and the public on incorporating vetted integrative therapies in cancer care to enhance outcomes. Dr. Nasha aims to bring integrative, bio-individual care to the women's health community and beyond. Dasha Maximov Dasha is a yoga teacher, health coach, and founder of WhealthCo. As the Director of Health Coaching for the PowHer Program, her goal is to impart to clients and other coaches the habits that are required to make long-lasting change in health happen and to bring forth the idea that health is not reductionist, but a symphony of cascading events and things in our bodies the create an environment for disease or for health. Kayla Osterhoff Former CDC Health Scientist, Researcher, and Health Optimization Medicine Practitioner formally trained across the spectrum of the health sciences. As the Director of Research and Development for the Women's Health Organization, she aims to use their pilot 12-month women's health cohort program (PowHer) as a vehicle to help bridge the gap in women's health research and build the evidence base for high quality women-centric health care. Key Highlights: How Nasha, Dasha, and Kayla came into this together Why women get left out of too many clinical studies About the PowHer program How is the program different from other programs out there? Critical things included in the program How does this amazing program work Optimizing women's health like never before How do the tests work Common misconceptions in women's health Your cycle is a superpower The program is limited to 30 women in the US and Canada this March How do people learn about the program? Program limitations such as the age range, health issues, health history, etc. Linkage: BioCurious Podcast American Board of Naturopathic Oncology World Health Organization Summit in London Whealth.co (Women's Health Community) on Mighty Networks Centers for Disease Control and Prevention Global Heart Initiative Ambien The Red Tent book Social links: Instagram: @powherprogram | @drnashawinters | @_dashofhealth | @biocurious_kayla Website: www.powherprogram.org

S1 Ep 25BPC157 - The "One Stop" Peptide for Body, Brain & Gut with Jean Francois Tremblay from CanLab
Everything You Need to Know About BPC 157 and its Practical Application in Anti-Aging, Muscle Growth and Health in General Jean-Francois Tremblay is an anti-aging expert and the owner of CanLab in Montreal, Quebec and a regular guest. In this episode, we dive deep into BPC 157, an incredibly versatile peptide that seems to have a positive effect on virtually every major system in the body. There are a plethora of different aspects of human healing that BPC 157 can assist with - from gut healing to healing of wounds, muscle, ligament, bone and tendon repair. It can also help to normalize blood pressure, improve brain health, ease withdrawal from alcohol and much more. Although there is no one peptide that can do all the work on its own, BPC 157 is one of the ones that may come the closest. It's one of a few peptides that in certain conditions can deliver results almost before people make significant changes to anything else. At this time most of the published research on BPC 157 is still mostly animal studies but we are gradually seeing an increase in human research - we still have much to learn but in this episode, we spend some time exploring what we do know and have seen. Meet this week's guest: Jean-François Tremblay is a frequent guest on this podcast. He is the founder and owner of Canlab - a lab in Montreal that synthesizes high quality peptides. Jean-Francois studied Exercise Physiology, Biochemistry, and Pharmacy at UQAM. He has been researching (in theory and in practice) peptides and SARMS since the 90's and has been studying the theoretical basis of what peptides are and their practical applications in sports performance, anti-aging, and health in general. Key Highlights: 4:32 What is BPC 157? 5:57 Does BPC 157 really work? 7:18 Using BPC 157 for gastric ulcers 8:08 BPC 157's effect on growth hormone receptors 9:11 How BPC 157 supports angiogenesis 14:11 Talking about cholesterol 16:35 Applications for Crohn's disease and Ulcerative Colitis 18:09 BPC 157 for repairing ligaments 18:59 How it normalizes blood pressure, vs lowering it 24:48 Nerve regeneration 25:29 It improves alcohol intoxication 26:51 Kidney support 27:54 The stability of BPC 157 and other peptides after reconstitution 29:19 Peptides that are used in cancer research 32:46 How fast does BPC 157 break down when we ingested? 34:47 Is BPC 157 bioavailable taken sublingually? 40:33 Tricks for using BPC 157 on an empty stomach 40:55 It resists more than we would predict with the digestive tract Connect with Jean-François Tremblay: Canlabsciences.com Promo Code: Niddam10 Disclaimer: This podcast is intended for information purposes only, none of the information is to be taken or used as medical advice. Before making any changes to your lifestyle, supplementation or nutrition please consult with your medical provider.
S1 Ep 24KetoneAid - Deep Dive on Ketone Esters with Frank Llosa –Ketone Esters fill a critical role in human physical and cognitive performance…could they even play a role in treating viral infections?
In this episode I deep dive into the fascinating world of ketone esters with Frank Llosa one of the most passionate entrepreneurs you will meet. By now, most of us have heard of the ketogenic diet – at its center are 3 fascinating molecules called Ketones – in this case, we are talking about beta hydroxybutyrate or BHB. While it is often talked about as a fuel source, it turns out the BHB is so much more than that as it is also an important signalling molecule that has wide ranging benefits to the human body. Ketone Esters are known for tasing awful and costing a small fortune but through utter dedication Frank has managed to make them palatable and more affordable in order to make this important compound accessible to more people including researchers who are still uncovering the many ways they can benefit human health. Links https://shop.ketoneaid.com Use Promo Code Longevity to save on shipping! Frank Llosa' s story – how he first became interested in Ketone Esters and his surprising connection to Dr Veech, a pioneer in Ketone research and science 6:35 Frank's first pitch to Venture Capitalists on marketing Ketone Esters was not exactly a winner… 7:20 The first competitive athletes who used Ketone Esters to improve their performance and how Frank ended up providing the initial seed capital to bring Ketone Esters to the market 9:25 The journey of bringing KetoneAid to market from sending them to athletes to Indiegogo campaigns… 14:47 How much of the KE1 and the KE4 do you actually need to use in one sitting and cost? 16:51 The different sports/athletes using Ketone Esters from Triathletes to half mile runners, how and why….is it helping muscles or brain? 18:30 Talking about Ketone esters and the brain – mouse studies that show that Ketogenic Diet can heal traumatic brain injuries in mice 20:45 The brain energy gap starts at age thirty 25:22 Ketone esters for Tour de France Athletes delivered 15% faster time trials… 25:52 Ketone Esters for recovery and the importance of timing Ketone esters right during athletic competitions… 27:02 How Greg Henderson former Tour de France athlete discovered that Ketone Esters not only materially improved his performance but also affected his recovery the next day…. 29:10 How should regular people use Ketone Esters around their workouts? No need to be Keto if you're using it fasted (and are used to fasted workouts). For alttitude workouts/results…. For hill workouts…. 30:37 The muscle groups that can actually use ketone esters and how this might impact how you train when using ketone esters 34:47 Ketone esters post workout for recovery and to manage excess caloric intake ….and to bring your brain online post workout. 38:02 the interplay between Ketone esters and glucose at the end of a race/event….it's all about lasting power sometimes even at the expense of peak performance.. 39:36 Using Ketone esters for cognitive performance – a couple of real life examples … 42:57 The good news/bad news of Ketone Esters and Caffeine…augmentation and replacement 46:12 Exploring why some people may respond better or faster to ketone esters than others – ketone transporters 50:22 Franks role in getting a (30 pages!) paper written on how Ketone esters may be helpful in supporting COVID19 patients…next step….clinical trials under way as we speak!! 53:19 Setting up the first clinical trial happening in Denmark to see how ketone Esters can support the heart in patients with severe COVID19 symptoms 53:59 The link between high blood glucose levels and worse COVID19 outcomes…could a Keto diet help long haulers? 1:01 Using Ketoneaid before bedtime for sleep… 1:04 A theory on why KetoneAid might be helpful for sleep…. 1:07 How Frank occasionally uses Ketones to pre-emptively mitigate the negative impact of insufficient sleep 1:08 Ketones may help to protect from harmful effects of radiation – for people living near nuclear power plants, when flying….an unpublished mouse study on how ketones massively increased survival rate of mice exposed to deadly levels of radiation. 1:13 Ketones and weight loss – how NOT to use them… 1:14 The difference between having ketones in your blood and actually being in ketosis. 1:16 Adopting a ketogenic diet before starting to use exogenous ketones of any kind… 1:19 Do people need to be on a ketogenic diet to get benefits from ketone esters? 1:20 Using Ketone Esters to fuel the brain energy gap, to extend a fast Links: KetoneAid.com Promo Code: Longevity to save up to $20 off shipping Disclaimer: This podcast is provided and intended for information purposes only, none of the information is to be taken or used as medical advice. Before making any changes to your lifestyle, supplementation or nutrition please consult with your medical provider.

S1 Ep 23Restore Youthful Levels of NAD from WITHIN your Cells an Interview with DR. Nichola Conlon CEO & Founder of NUCHIDO
Dr Nichola Conlon from Nuchido talks about why simply taking NAD is not enough to solve your NAD deficiency. Have you ever asked yourself why NAD levels go down as we age? After all, our cells are built to recycle NAD - so why on earth is everyone so deficient? In this episode I dig deep into the issues of NAD deficiencies due to aging or disease and, TIME+ a supplement that may just provide the missing link in restoring youthful NAD levels. To try TIME+ for yourself: Nuchido.com Promo Code: Longevity10 saves you 10% Episode Notes: 4:51 All about Nichola, she looks 22 but definitely isn't, she has an 11 year old daughter. What she got her PHD in and more about her background. 6:40 Nutrient transport and how it actually gets transferred into the cell 9:30 How drug companies go about creating a solution. Single target approach 10:10 Biology is very complex, every pathway is connected, and expecting a drug to only affect one thing is not ideal. 11:00 The body has backup plans, the body is resilient 12:00 Why drugs have side-effects 14:00 The multi target approach and why it's important 16:00 How aging and drug development came together 18:00 How Nuchido was born 20:24 How this supplement addresses NAD in the cell (totally unique) 21:00 Why just hoping that NAD gets to right place is not ideal 22:10 NAD is estimated to be involved in 500 different reactions in the body 23:00 When maintenance and repair pathways get turned down 24:05 The cycles of NAD that we want 25:55 How damage to the cells/aging correlate with NAD 26:15 By the time we're 20, we've already lost half the NAD we're born with, but there's good news! 27:00 Why NAD levels naturally decline, and certain diseases decrease NAD 27:35 Chronic fatigue syndrome 27:57 The people who will notice the greatest benefits from Time+ 29:50 Lifestyle factors that affect your NAD levels 31:00 Mitochondria, lyme disease and even COVID-19 34:00 How MOST supplements boost NAD through precursors NMN and NMR 37:00 The problem with relying on precursors, and why the root cause is so important 37:57 Enzymes and NAD\ 38:20 Why in some cases taking precursors is actually worse than not taking them 39:50 Methylation and why you may need to take a methyl donor if you take precursors 40:50 The importance of NAD and NADH balance 41:30 Instead of just adding to the factory, fix the factory so that it works well 46:00 NMMT 48:00 The optimal ratio of NAD and NADH 52:00 Can NAD+ be found in nutrition? 57:30 Ingredients in Time+ and why you shouldn't be worried if you accumulate high levels of zinc 59:20 Why green tea is so amazing, egcg and methylation 1:01:24 Why parsley is so important 1:09:00 Why whole systems are so important 1:11:40 Senescent cells and why you should pay attention to this! Disclaimer: This podcast is intended for information purposes only and none of the information presented should ever be taken as medical advice. Consult with your physician or medical provider before making any changes to your diet or lifestyle (including starting new supplements).

S1 Ep 22Functional Practitioner Series featuring Dr. Michael Meighen
Dr Michael Meighen This episode is part of the "Functional Practitioner Series" where I interview physicians who have evolved their medical practices to encompass the principles of functional medicine. The physicians are practicing an evolved for of medicine and have gone beyond the borders of allopathic medicine all while preserving an evidence based approach. Dr. Michael Meighen is a musculoskeletal expert and health optimization specialist focusing on the total transformation of his patients. He is the author of the #1 best-selling Amazon book called A New You; Using the Body's Regenerative and Restorative Powers to Optimize Orthopedic, Hormonal, and Sexual Health Function. Dr Meighen holds board certifications in Physical Medicine, Rehabilitation and Pain Medicine and has over 20 years of experience. His treatment plans primarily concentrate on conservative and non- operative measures to help the individual improve their function, pain control, mobility, and longevity. Dr Meighen applies evidence-based interventions to restore, regenerate, and rejuvenate his patients allowing them to live a truly limitless life. He has integrated proactive approaches including fitness and strength training, mindbody techniques, hormone optimization, regenerative interventional orthopedic medicine, peptides, epigenetic testing, sexual health interventions, and aesthetic procedures to maximize health span and vitality. Dr Meighen's philosophy is that clients will progress and evolve if they are accountable and embrace the process. Beyond this he believes that the client must become comfortable with being uncomfortable and be willing to push the limits of precision medicine to become a super being. Dr Meighen's office is located in Nashville Tennessee and he also practices telemedicine to serve out of state patients and clients. Website: www.livelimitlessmd.com Email: [email protected] Disclaimer: Please note that this interview is intended for information purposes only and that none of the content is to be taken as medical advice. The opinions expressed by the guest and host are in no way to be applied by the individual in lieu of medical advice and all such changes (lifestyle, diet, supplementation etc) should first be cleared with your medical provider.

S1 Ep 21Chronomics: How Old Are You REALLY?? Comparing what your birth certificate says to what your DNA says with Chronomics Chief Science Officer Daniel E. Martin Herranz
Your Birth Certificate says you're 35 but how old does your DNA say you are?? How great would it be to be able to see how fast (or slowly) your body is aging? Or to measure the impact of all those anti aging supplements, your regular meditation practice and that new diet you adopted 3 months ago?? It turns out that there are now companies that can give you that insight with just a few drops of your saliva…Chronomics is one of those companies – my guest today is Daniel E. Martin Herranz the Chief Science Officer and Co-Founder of Chronomics and we talk about the science of epigenetic aging, what we know and don't know and how people are using this test to quantify the benefits (or downsides) of how they live their life. If you're interested in gaining these insights you can get a whopping 55% discount on the test for yourself by using this link: chronomics.com/natniddam 01:17 Meet Daniel E. Martin Herranz - A young guy in the business of aging 02:20 How rubbing shoulders with leading biotechnology professors and meeting Dr. Thomas Dobsons, got him to his current position of CSO and co-founder of Chronomics 04:08 How to get healthier and happier: Chronomics' vision to make very complex biological data accessible to everyday consumers to improve preventive health care 05:33 The innovation of Chronomics COVID test is its use of a saliva sample – easy, painless, and you can do it at home 06:41 Crossing the pond from the UK to North America and other parts of the world to provide at home PCR COVID testing 10:30 How accurate is the Chronomics Coronavirus saliva testing kit? 12:56 All about the preventive healthcare test by Chronomics 14:10 Behind-the-scenes of the epigenetic test. What happens after they receive your saliva sample? 15:26 What is epigenetics and how can it help quantify aging? 17:04 Using next-generation sequencing to accurately quantify DNA 18:12 Artificial Intelligence and machine learning: the technologies which help quantify your biological age, age-associated risks, mortality and age-related diseases, and risk factors 21:16 Many complex phenotypes are the result of a complex interaction between hundreds or thousands of genes along with your lifestyle and environment 22:25 Epigenetics can help us get insights into the effects of our lifestyle and environment with our genetics 24:37 Genes are not your destiny – the right lifestyle choices can compensate for your predispositions 26:53 The epigenetic test is a tool that tells you how well you're doing but you're responsible for changing your lifestyle to improve your outcome 28:24 Preventative health care lacks the tools to accurately quantify our health before we develop a disease 31:40 APOE ε4 gene: any lifestyle interventions to decrease the risk, delay the onset, or avoid it completely? 33:35 How epigenetics can give you the tools to determine if you're going in the right direction to reduce the chances of developing preventable diseases 35:27 Focusing on the 4 main epigenetic biomarkers in the Chronomics epigenetic test 36:21 The biological age biomarker quantifies your aging process 37:02 Metabolic risks at the epigenetic level 37:41 Quantifying the silent killers with two biomarkers dedicated to exposure such as toxins from tobacco smoke and air pollution 38:28 Alcohol footprint biomarker gives a better value to quantify your risk derived from alcohol exposure 40:28 Epigenetics test results are 100% DNA-based, with recommendations from both the epigenetic test and the lifestyle questionnaire information with the goal of providing actionable and positively impactful guidelines. To learn more about Chronomics: Chronomics.com Link to Buy the test at a 55% DISCOUNT: https://www.chronomics.com/natniddam Disclaimer: This podcast and all the content within is intended for information purposes only and should never be taken as medical advice. Please always consult with your physician or medical provider before making any changes to your diet or lifestyle (including starting new supplements).

S1 Ep 20The Ultimate NAD episode with Jeanne Pitre & Tom Ingoglia from the Longevity Collective
The ultimate NAD episode with Jeanne Pitre & Tom Ingoglia from the Longevity Collective and Longevity Underground. My guests today are partners in an incredible new venture with a mission to bring NAD to people everywhere including those who need it most. Their mission: To cure addiction, to optimize brain health AND to increase lifespan by 20 years. In this episode we talk about the many different ways that NAD can be used as well as where it's precursors NR and NMN fit in. Jeanne Pitre is a Nurse, a Naturopath and a Healer who has 14 years experience as an NAD infusion specialist, so when it comes to the finer points of using NAD for whatever application she is THE one to go to!! Tom Ingoglia is a businessman with a health journey that took him from being a healthy, vibrant and successful executive to the brink of despair as a mysterious illness and subsequent efforts by the medical establishment to treat him robbed him of his health and rendered him a pain ridden shadow of himself dependant on pain medications to get through the day. After years of suffering he was finally able to reclaim his life through the discovery and use of NAD. Between the two of them they have published research, attended and organized NAD conferences and rubbed shoulders with many of the leaders in NAD research. They have founded a not for profit - The Center for Research and Brain Health also known as The Longevity Underground, as well as The Longevity Collective an e-store selling Transdermal NAD patches & sublingual lozenges. Tom and Jeanne are on a mission and we all stand to win from what they have set out to achieve. In the meantime, they generously sat with me and shared their knowledge, their stories and so much more…so pour yourself a hot or cold drink, grab a pen and paper and let's dive in to the world of NAD. Here are a few time stamps to orient you through the interview: 14:34 Longevity Diagnostic Research – developing a test that can establish individuals' innate NAD levels and best course of action to restore them 19:00 The types of NAD supplements available now at Longevitycollective.com (promo code Longevity15) 22:00 How to decide which route of administration is optimal for an individual – choosing between intranasal, sublingual, SubQ or IV 27:00 Bioavailability of different forms of administration 29:00 What NAD does at a cellular level… and why it seems to affect people differently 36:00 Tom Ingoglia's incredible health story…. 44:00 Floxies, CFS, Lyme – all respond differently to NAD and other treatments – why low and slow is the only way to go 51:00 The questions to ask next time you are going in for an NAD infusion…the results you can expect to experience… 56:00 Turning the clock back to 1948, the first NAD IV's in Italy to treat morphine addiction 60:00 The connection between NAD and brewer's yeast, pellagra and…Covid? 1:02 How NAD treatment may hold one of the keys to treating veterans, addicts…. 1:07 Longevity Underground – ultimately searching for ways to fund and run clinical trials to help the homeless, veterans, elderly and COVID populations 1:09 Callout for volunteers to join the Longevity Undergound…. 1:11 Tackling the issue of using precursors to NAD, do they work? Who might they not work for? 1:16 The work that Elysium is currently doing with ALS patients; NR that is showing results 1:24 Jeanne's take on why some people may just need to be long term users of NAD… 1:26 Possible caution around using NAD in the presence of certain types of cancer… Links: LongevityCollective.com LongevityUnderground.org (not-for- profit) Promo code: Longevity15 to get 15% off your purchase of NAD products Links to Research Articles: Link to the NAD Movie trailer: https://vimeo.com/486042597/10149ba6ef funded by: Longevity Underground/Center for Research on Addiction and Brain Health (CRABH) Study making the case that NR is more bioavailable orally than NMN. https://www.nature.com/articles/ncomms12948 …. 2 excellent scientific articles about NAD+ and Cancer: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507617/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315198/ This article references Joseph Goldberger, a pioneer in NAD+ treatment utilizing Brewer's Yeast to cure Pellagra https://dm5migu4zj3pb.cloudfront.net/manuscripts/21000/21205/cache/21205.1-20150302084731-covered-253bed37ca4c1ab43d105aefdf7b5536.pdf COVID and Niacin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428453/#:~:text=Recent%20evidence%20indicates%20that%20targeting,with%20ventilator%2Dinduced%20lung%20injury. https://www.nature.com/articles/s41418-020-0530-3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428453/ Please note that this podcast is for information purposes only!! None of the content is intended as medical advice – before undertaking any new health initiative be it a change in diet, lifestyle or supplementation please consult with your medical practitioner!!
S1 Ep 19Brown's Gas - Molecular Hydrogen with a twist - Target immune function, longevity, wound healing, inflammation and soooo much more!
In 2005 George Wiseman, an inventor discovered that a device he had created to solve an industrial problem actually could provide incredible benefits. He had stumbled upon a delivery system that produced Molecular Hydrogen as well as a fascinating compound called Brown's Gas (BG). BG can be consumed as a gas to be inhaled, applied topically or that can be bubbled through water to be drunk or applied topically with fascinating results. In this interview, we explore George's personal healing journey and how he has helped thousands of people on theirs....from better immunity to balanced metabolic function, George credits this technology for his personal transformation and has witnessed it do the same for many of his customers. There's also a ton of research backing this up which you can access at https://eagle-research.life as well as a multitude of testimonials that have been submitted by his customers over the years. Some foundation info: What is It? A gas produced from water consisting of 2 parts Molecular Hydrogen and one part molecular O2 - it is also called OxyHydrogen, HydrOxy and HHO. BG is formed in the absence of a membrane between the Anode and Cathode used to electrolyse the water. BG Discovered in 1960 by Dr William Rhoades (US) Further studied for 30 Years by Dr Yull Brown (Aus) 1984 - George Wiseman founded Research and developed a Torch that harnessed BG for Industrial Purposes. 2005- George starts to use BG himself . Within weeks he notices marked improvements to his health.(discussed in interview). 2016 - Starts inhaling the gas and experiences more shifts in his health. https://eagle-research.life ships worldwide For 10% off use promo code: Vitality 7:42 What is Brown's Gas and how does it occur? 10:00 Customers start experimenting with Brown's Gas for reasons...including one jaw dropping example of healing... 12:26 After Tyler Lebaron consulted with him in the early 2000's about Hydrogen for health, George was convinced to use Hydrogen and Brown's gas for his too …. 13:20 Conditions that George has seen resolve since he started first drinking Brown's Gas and eventually inhaling it…. 14:34 Korea is on to this technology 17:31 Brown's Gas is a powerful oxygen reduction compound when you bubbe the gas through water . It seems to be a "much stronger" antioxidant. 19:21 "Electrically expanded water" 19:40 The difference between H2 Machines and Browns Gas Machines. 20:48 The real 4th State of water 21:30 Drinking tap water may suck energy from your body 23:58 Why people get sick and the benefits of Molecular Hydrogen (H2) that can help improve peoples' outcome 25:25 How Hydrogen may improve digestion and how the ingestion of toxins like Glyphosates and antibiotics may be driving hydrogen deficiency. 27:20 Some of the conditions that George attributes healing to Brown's Gas and Hydrogen 28:33 How to make sure Browns Gas is safe for home use…. 30:28 Hydrogen as a major macronutrient 30:35 The big difference between Hydrogen and Brown's Gas 33:45 Can Brown's Gas be too much of a good thing for healthy young people? 35:00 Interesting facts about longevity and how Brown's Gas may play a role… 36:09 Human study in Japan comparing the Hydrogen levels in longer lived families vs shorter lived families... 40:45 Back to George's personal journey after starting to use Brown's Gas - better immune function, GI function, vision, weight loss 44:00 The first condition that resolved when George started inhaling BG…..and other conditions that may positively be impacted by inhaling BG... 46:50 How many hours a day should you use Brown's Gas…. 48:30 "The weirdness" phase aka adaptation to increased levels of hydrogen... 49:50 Drinking Brown's Gas and 4 ways to use it 56:30 The Power of n=1 57:00 For arthritis 58:00 For wound healing 59:25 George's Diet and how it has evolved…. 1:08:18 Where to find scientific studies on his website https://eagle-research.life 1:13:18 Is Brown's Gas more stable in the than Molecular Hydrogen? 1:14:20 The thing that Nathalie does on planes causing fellow passengers to turn and stare…. 1:16:40 When should you consume Brown's Gas - Pre or post workout? https://eagle-research.life ships worldwide For 10% off use promo code: Vitality Please note that this video is for information purposes only and is not intended to substitute for medical advice, diagnose or treat any disease or medical condition. Always seek the advice of your physician or care provider before starting any new treatment, making changes to your diet or lifestyle.
S1 Ep 18Improving Boardroom Cognition with Dr. Suzanne Turner - Supercharge your brain to perform at its highest level with peptides, nootropics and much more!!
Suzanne Turner – Improving Boardroom Cognition Supercharge your brain to perform at its highest level with peptides, nootropics and much more!! In this episode I have a great discussion with Dr Suzanne Turner and dig into the ways she helps her patients to keep their brains young and optimized no matter what their age so that they can enjoy as good (if not better) function in their later years as they did in their prime. If you're still in your prime you will get a ton of value from this episode too as many of these are also great strategies to optimizes a young brain. Dr Suzanne Turner is the founder of Vine Medical Associates. She is double Board Certified in Family Medicine and AntiAging and Regenerative Medicine, she treats rare and unusual diseases in patients from around the world. Practicing Functional Medicine, Dr. Turner is an industry expert and speaker on bioidentical hormone therapy, metabolic medicine, neurodegenerative disease, and human performance optimization. She has earned Advanced Certification in Endocrinology and Peptide Therapy and is the leading expert in peptide therapy in the Southeast. Among her many accomplishments, Dr. Turner served as a physician in the U.S. Navy for several years. Prior to her tour of duty, she did an internship in general surgery, then completed her residency at Emory University. Dr. Turner is also an award-winning teacher of medical students and is on the faculty of A4M, IPS, ACAM, and SSRP. 05:44 Why Dr Turner picked Boardroom cognition as a topic to deep dive into: and, what busy moms and boardroom executives have in common 14:25 Sleep a critical piece of the puzzle 19:50 How many hours it actually takes the brain to get into ketosis and why this is so important to cognitive health 22:50 The best time to have a glass of wine to mitigate negative effects 24:53 The cellular impact of alcohol 26:44 Muscle – the currency of aging 27:26 Resistance training as a strategy to decrease the need for insulin in diabetics 28:08 A healthier way to mitigate oxidative stress Ketone Esters instead of antioxidants 29:20 Hydration for cognitive performance 33:47 Hormone Optimization as a strategy to optimise cognitive function 35:23 Optimizing immune function –for brain performance – Thymosin Alpha 1 the first peptide in your stack 37:08 The magic of the 40 Day or 6 week cycle 38:23 DiHexa and how to use it for maximum benefit 43:20 When it makes sense to introduce Selank and Semax 44:11 How GLP1 Agonists fit in to supporting cognitive performance and why nobody talks about them for this purpose 45:10 Cerebrolysin – how and when to use for cognitive support/performance, stacking with DiHexa for the win 51:41 Nootropics that can work and bring added value – the ones to exercise caution with – from Qualia Mind to Mucuna, Phenibute, to L Carnitine 56:00 Modafinil – great for the right person but beware the "Elvis Syndrome" 57:56 Spermidine, how it supports autophagy in the brain and how this too can support optimal function 58:55 Rapamycin to clear senescent cells that could be clogging "pathways" for "cognitive decline" prevention, when to take it for optimal results. Links: Vine Medical: https://vinemedical.com Dr Turner's Website https://drs.md/ Instagram https://www.instagram.com/drsturner/ Facebook https://www.facebook.com/DrSCellularMedicine QualiaMind http://bit.ly/QNHNat Promo Code: NN15 for 15% off Primeadine (Spermidine Supplement I recommend) Primeadine.com BIONAT15 for 15% off your purchase Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

S1 Ep 17Spermidine – The Powerful AntiAging compound you've never heard of but is about to take the world by storm
Primeadine Spermidine – The Powerful AntiAging compound you've never heard of but that is about to take the world by storm. In this episode I sit down with Leslie Kenny the CEO and Founder of OxFord Healthspan – a company founded for the purpose of bringing powerful healthy/anti aging compounds to market. Today we deep dive into their first entry which is rooted in ancient knowledge and yet relatively new to the modern world. Consider that this compound hits at least 5 of the 9 hallmarks of aging….even better, new research seems to point to its ability to improve immune response in elderly adults by helping certain areas of the immune system to reboot and rejuvenate!! Oxford Span is committed to making this supplement available to as many people as possible – for the month of December you can benefit from introductory pricing PLUS an additional 15% discount (BIONAT15 promo code). If you are this after December 2020 the discount code will still work!! Note that this supplement will produce most noticeable results in the 50+ crowd who are already seeing a decline in endogenous spermidine production and is not appropriate for people with celiac disease or severe wheat allergies – we talk about all this and more in the episode….enjoy!! 6:08 Leslie's story – from autoimmune disease & infertility to how she first came across spermidine 7:22 The link between ancient Japanese scrolls on longevity and sexual intimacy and spermidine 11:05 Compounds that target the 9 hallmarks of aging and the 5 specifically targeted by Spermidine 13:30 Dietary sources and the reason why supplement companies are having to extract spermidine from wheat instead of Natto 15:30 Natto – possibly the best and most economical source of spermidine 17:33 Who should NOT use the current Spermidine supplements (including Primeadine) and why 18:02 Amount of gluten per serving vs a slice of 19:54 Why the 50+ crowd is likely to experience the best visible results from Primeadine 20:55 Endogenous and exogenous sources of spermidine 22:57 The physical signs that your spermidine production is declining 28:20 Short, medium and long term benefits 36:05 Maximum dose as determined by regulatory bodies 38:49 Getting back to the ancient Daoist Scrolls – the aging male's advantage over women 45:29 Best time of day to take Primeadine 50:27 DO NOT mix with hot foods or beverages 52:25 Introductory pricing in place until December 31, 2020 15% discount code in place for December and the new year: BIONAT15 Website: Primeadine.com or OxfordHealthSpan.com Just a few of the growing list of studies assessing Spermidine's possible benefits for human and longevity Studies/References Effect on Hormones, Fertility in men and women The regulatory effect of biogenic polyamines spermine and spermidine in men and women. Open Journal of Endocrine and Metabolic Diseases, 9(03), 35 Spermidine Intake and Longevity in humans Higher spermidine intake is linked to lower mortality: a prospective population-based study. The American journal of clinical nutrition, 108(2), 371-380 The autophagy enhancer spermidine reverses arterial aging in aged mice. Mechanisms of ageing and development, 134(7-8), 314-320. Okamoto, A., Sugi, E., Koizumi, Y., Yanagida, F., & Udaka, S. (1997). Polyamine content of ordinary foodstuffs and various fermented foods. Bioscience, biotechnology, and biochemistry, 61(9), 1582- 1584 Ramot, Y., Tiede, S., Bíró, T., Bakar, M. H. A., Sugawara, K., Philpott, M. P., ... & Paus, R. (2011). Spermidine promotes human hair growth and is a novel modulator of human epithelial stem cell functions. PLoS One, 6(7), e22564 Rinaldi, F., Marzani, B., Pinto, D., & Ramot, Y. (2017). A spermidine-based nutritional supplement prolongs the anagen phase of hair follicles in humans: a randomized, placebo-controlled, double- blind study. Dermatology Practical & Conceptual, 7(4), 17. Schwarz, C., Horn, N., Benson, G., Calzado, I. W., Wurdack, K., Pechlaner, R., ... & Flöel, A. (2020). Spermidine intake is associated with cortical thickness and hippocampal volume in older adults. NeuroImage, 221, 117132 Dietary polyamine intake and colorectal cancer risk in postmenopausal women. The American journal of clinical nutrition, 102(2), 411-419 And finally an article on new findings of the effects of Spermidine on immune function is elderly humans: https://www.longevity.technology/autophagy-in-t-cells-maintained-by- spermidine/?utm_source=ZohoCampaigns Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition before you make any changes.
S1 Ep 16BioHack with Breath Work - One Hour with JP Crimi = 20 Years of Therapy. How This Unique Style of Breath Work Can literally Transform Your Life & Your Health
Breath Work with JP Crimi This episode could possibly change your life in as little as one hour for less money than you spend in an average week on coffee. Breath work is nothing new but I can promise you that you've never experienced it quite like this before. Jon Paul Crimi has developed a technique that he delivers live online every Sunday to people from all over the world - you owe it to yourself to try it just once. In this episode you'll get a taste of JP and what breath work might just help you to access in yourself...check it out, sign up for a class and then send me a note to share your experience - I guarantee that you won't regret it!! Enjoy!! 01:18 Introduction to John Paul Crimi - from Boston to LA Sobriety Coach to the Stars to today 6:18 the autoimmune condition that ended JP's acting career and launched him on the journey that led to where he is today… 13:13 How a Stanley cup Final Hockey Game in 2012 with Matthew Perry led to an audience with Tony Robbins...the next step 17:07 Conscious Connected or Circular Breathing what it is and how JP came to develop his own style... 21:54 The benefits of Live online classes vs Live classes 23:04 What is it about crying that is so essential for your health 24:14 HOW Breathwork clears the way for transformation in every part of your life differently than therapy 27:21 Turning off your inner critic 29:56 Breathwork as a gateway to meditation... 33:25 Using breathwork to help resolve physical issues 35:49 The difference of JP's breathwork classes - the power of the right music and a coach who pushes you to your limits… 39:00 JP's deal with the universe and ultimate goal… 43:56 Becoming a Breath Work teacher…. To try a class for yourself: https://www.breathewithjp. On Instagram: @jonpaulcrimi

S1 Ep 15Love Your Liver Episode: Bioregulators and peptides to support the Liver with Jean-Francois Tremblay from CanLab Research
In this episode Jean-Francois Tremblay returns for a deep dive into Liver health. Too often the liver is our forgotten hero. Your liver is responsible for detoxifying hormones, toxins, processing fats, making cholesterol, storing energy and so much more….and all to often we abuse it and leave it struggling under an overwhelming burden until it just can't cope anymore - it fills with fat, gets slow and sluggish, cholesterol and triglycerides build in the blood stream, toxins go unchallenged and chronic preventable diseases start to take hold. Join us to talk about ways to support your liver and how bioregulators and peptides may be part of the solution. Some of the topics we cover: ● 01:32 What is non-alcoholic fatty liver disease? ● How the Bioregulator Livagen and CanLabs' new Peptide Combo (LRP, LQP, GPETAFLR) may help treat non-alcoholic fatty liver disease ● Differentiating between therapeutic (treating an existing problem) and preventative use of peptides and bioregulators ● The concept that "Therapy is not the peptide, the peptide is part of the therapy". ● Fatty liver peptide research ● How long it could take to see results…. ● Assessing the quality of your peptides ● Using HPLC to measure peptide purity ● Precautions on peptide purity Disclaimer: Canlabresearch.com (promo code Niddam10 for 10% off anything in the store) Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.
S1 Ep 14The Antioxidant Myth, Losing Fat and Building Muscle with Novel Peptides with Dr. Elizabeth Yurth
Elizabeth Yurth, MD is the Medical Director of the Boulder Longevity Institute which she co-founded in 2006. The Boulder Longevity Institute specializes in advanced, research-based longevity medicine including treatments such as Bioidentical Hormone Replacement Therapy and Regenerative Peptide Therapy. Dr. Yurth is double board-certified in Physical Medicine & Rehabilitation and Anti- Aging/Regenerative Medicine. As a specialist in Sports, Spine, and Regenerative Medicine, Dr. Yurth has a Stanford-affiliated Fellowship in Sports and Spine Medicine, and a dual-Fellowship in Anti-Aging and Regenerative Medicine (FAARM) and Anti-Aging, Regenerative and Functional Medicine (FAARFM) through the American Academy of Anti-Aging Medicine (A4M). Dr. Yurth has been selected as one of the 25 mastermind physician fellows in SSRP (Seeds Scientific Research and Performance) which allows her to stay abreast and teach others in the emerging field of cellular medicine. An active herself, Dr. Yurth has consulted with numerous sports teams including the 49ers and the Stanford women's and . She has served as a Physician for the / Ballet. Dr. Yurth resides in Boulder, Colorado with her husband and five children. In this episode I sit with Dr Yurth (or Betsy as she prefers to be called) and we talk about the common and yet complex issue of building muscle and losing fat mass. As so many people have discovered this is often nowhere nearly as simple as we think it should be, particularly as people get over the age of 45. We talk about lifestyle, hormones, exercise, and of course - peptides including two peptides that are rarely considered when someone is trying to "lose weight" or, as we prefer to say - improve their body composition. It's a great episode - and if you get value from it, here are ways you can support the podcast - leave a written review on whatever platform you are listening on, share it with your friends and family….and remember that you can connect with me on Facebook or MeWe in the Biohacking Superhuman Performance Group or, if you're interested in working with me or have any comments about the podcast through my website NatNiddam.com. Show Notes: 8:00 Alcohol's negative effects on weight loss & hitting your goals (if you are a committed drinker you may not enjoy this part of the podcast 😉) 10:40 The myth about antioxidants 15:50 SSRP Mastermind - Medical Practitioners coming together on developing Peptide Protocols taking a cellular approach…. 19:40 Identifying obesity and its associations with other diseases 22:00 The link between obesity and inflammation - what comes first? 23:00 Peptides for weight loss - where does Thymosin Alpha 1 fit in? 25:30 Where does Molecular Hydrogen fit in? 28:00 Setmelanotide - for hunger management - strategic use 20:00 MotsC as an exercise mimetic in certain cases... 30:40 The relation of growth hormone levels, weight loss, and ageing 32:00 Growth hormone secretagogues for weight loss - Tesamorelin, CJC/Ipamorelin 34:20 How long workouts may be working against you if you're trying to lose weight 36:00 Figuring out your eating window 41:11 Digestion and digestive enzymes 43:08 AOD 9604 - does it work? Relation of dosage, effectivity, and cost for fat loss peptides 44:28 Oxytocin for fat loss, increasing lean mass and bone production 48:00 How to use oxytocin based on desired result – nasal spray vs injection vs injection 01:02 Ketone Esters for fat loss by reducing inflammation 01:06 Exercise for Fat Loss - weight lifting, bands, Hiit, Body weight exercises instead of long duration cardio To connect with Dr Elizabeth Yurth - http://boulderlongevity.com To connect with Nathalie - https://www.natniddam.com Join Us on MeWe in the Biohacking Superhuman Performance Group: https://mewe.com/group/5d59c5d80264794bb98d124b Or on Facebook: https://www.facebook.com/groups/462749384302295 Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your care provider. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

S1 Ep 13A portable AND affordable Red Light & Near Infra Red Light device that can help to heal your injuries, improve your skin, improve your immunity, your gut health and more…Dr Zulia Frost shares all on the new FlexBEAM…
The FlexBEAM is a tiny and mighty new entry in the photobiomodulation space - the team at Recharge set out to make the safest, most powerful, portable and affordable red light and near infra red light device on the market and it is finally available to you! In this interview I talk to Dr Zulia Frost co founder and co creator of this incredible device and we talk about how to use it and all the things it can do including: Support Immunity Speed up healing of injuries Reduce Pain Support and improve gut health Target specific organs And much much more… Use this link https://bit.ly/FlexBEAM2 and discount code Longevity30 to save $30) Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment.Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.
S1 Ep 12Dr Amber Part 2 on Mitochondrial Energy: MotsC and NAD
Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your care provider. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition before you make any changes.
S1 Ep 11Sleep Crown: The Sleep Hack You've Never Heard of that will Supercharge Your Sleep
https://www.natniddam.com/ https://www.sleepcrown.com/ Longevity10 saves you 10% off Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

S1 Ep 10Why You Need to Optimize Your Hormones BEFORE anything else with Caleb Greer FNP-C - the best kept secret in functional medicine
In my opinion Caleb Greer is one of the best kept secrets in Functional Medicine. One of his many superpowers is his ability to take the best from the world of conventional medicine and marry it to Functional practice to get his patients the results that they seek. From hormone optimization to peptides, personalized nutrition to the judicious use of pharmaceutical compounds when they are called for - Caleb covers it all - which is why Caleb and I will often collaborate on optimizing clients' results…this podcast is just an intro - stay tuned for more episodes where we dive deep into various topics. For today, we start with hormone optimization. Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

S1 Ep 9Deep Dive into Molecular Hydrogen with Alex Tarnava
Alex Tarnava of HRW https://drinkhrw.com/ Promo Code: Longevity10 to get 10% off your purchase 0:11 Alex Tarnava and DrinkHRW 1:06 DrinkHRW aims to get messaging right and put forth an honest and accurate voice 02:52 How Alex Tarnava got into molecular hydrogen 04:09 From fit to sick 08:26 Hydrogen as a viable option to regulate inflammatory response 10:12 Hydrogen Testing 10:56 Getting the right amount of molecular hydrogen 11:15 Cautionary tale about molecular hydrogen products 12:34 What drove Alex to create HRW 15:44 Initial stages for hydrogen tablet 16:49 What it takes to scale production 21:27 Marketing the Hydrogen tablets 21:42 Alex's Ethical requirements: doing good rather than just making money 22:20 Clinical outreach program 22:38 The underlying issue on pharmaceutical and supplemental research 26:14 How much you need to use to dissolve your Hydrogen tablets and why... 28:42 Dissolution kinetics when mixing hydrogen tablets with 29:36 How to get the highest dose of hydrogen 29:59 Hydrogen is most effective during intermittent high dosing Molecular Hydrogen and…. 32:29 Metabolic syndrome 32:49 Multiple research and clinical trials about the benefits 34:12 Rodents, hydrogen treatments, and Parkinson's Disease 39:25 Traumatic Brain Injury 41:02 Oxidative stress, inflammation, insulin sensitivity 44:44 Molecular hydrogen as a selective antioxidant? 46:19 Restoring proper functions in the critical systems in our body and not as a pharmacological agent 47:12 Molecular Hydrogen and Fasting 48:48 The need for better evidence about Fasting in the Biohacking community 51:40 Panacea contributes to the reluctance of researchers to publish studies 52:25 The need for a cultural shift within biohacking and integrative medicine 53:08 There's no toxic dose of molecular hydrogen 55:11 Bath tablets: absorbing hydrogen through the skin 57:43 Why adding lemon to your hydrogen is a good idea beyond taste 58:23 Topical application for molecular hydrogen 59:47 Alex's new project: Myjourney. and biohacking 1:01:36 About wearable technologies 1:06:29 The goal of Myjourney. 1:09:18 Helping researchers explore the best benefits of various biohacks via myjourney. research grants 1:09:56 Data privacy and community collaboration Links: https://drinkhrw.com/ Save 10% off your with promo code: Longevity10 @drinkhrw (Instagram) Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Before changing your diet or using any new supplement make sure to consult with your care provider. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

S1 Ep 8Cellular Senescence, Why the Goldilocks Approach is the ONLY way to go and SELANK: more than just another brain peptide
Dr. Seeds is a board-certified orthopedic surgeon and physician specializing in all aspects of sports medicine and total joint treatments. With over 22 years of experience, Dr. Seeds is focused on providing the most innovative results to those seeking to maximize their performance, relieve injuries, and live a healthy lifestyle. Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.
S1 Ep 7Repair Peptides: TB500 vs Thymosin Beta 4, they are NOT the same
Thymosin Beta 4 and TB500 - are they one and the same? NO! We are BACK!!! In the peptide world these two peptides are often referred to interchangeably....as if they were one. And yet - they are most certainly not! In this short interview Jean-Francois Tremblay from CanLabs explains how they are related but quite different and how they may work together in certain scenarios. Remember - none of this information is to be used as medical advice ...there is a LOT we do not know about peptides hence peptides are still rated as "research chemicals" so before you even think of using these please consult with a medical professional to assess any risks. 5:00 Amino acids 17-23 6:30 Anti-fibrotic 7:00 Why people interchange TB500 and Thymosin Beta 4 9:00 If you want a tan just take melanotan2 9:10 For sensory effect take this peptide 9:30 If you want more take this peptide 9:50 "Moron proof" peptides 12:30 Neuro benefits of Thymosin Beta 4 14:15 Used for race horses 15:20 Number of peptides in Thymosin Beta 4 chain. 15:45 How to double names and peptides: the number 23:00 The of peptides 23:50 Cost effective 26:00 TB4 pills and the issue of digesting 27:30 How peptides digested work with leaky gut better in the beginning 31:40 BPC-157 is an orally available peptide 32:40 TB500 hones in on musculoskeletal system https://www.canlabresearch.com/ Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your care provider. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition before you make any changes.
S1 Ep 6Find Out How Fast (or Slowly) You're Aging with Épi-Age & Dr Moshe Szyf
Dr. Szyf is a pioneer in the field of epigenetics, he holds a PhD from the celebrated Hebrew University, a postdoctoral fellowship in Genetics at Harvard Medical School, a Professorship at McGill University and a Chair in Pharmacology at GlaxoSmithKline. 5:33 DNA as the operating system of our lives 6:14 Disease causes disruption in the DNA 6:41 DNA methylation gives us an insight into what's going on in our DNA 7:07 Epi Age testing can tell us how many years we've been living in this world, and may give insight into how many years we may have left 8:02 Chronological age and epigenetic age can be good indicators for life span 11:17 Epi Age is a lifestyle product 12:59 Identifying the markers for aging 14:23 How Epi Age is different 17:05 What are the most effective ways to slow down the clock? 17:29 Behaviours that can help slow down the clock 18:28 epiAging app 19:51 epiAge test results tell you what you're DNA thinks of what you're doing 22:21 The first step in slowing down the clock is to get to a state of balance 23:58 Using AI to derive some conclusions from an individual result against a general lifestyle model 24:30 The great revolution will come from mathematics and technology to capture the complexity of humans 26:24 The idea of sharing -- creating a "Waze" of health 27:08 Health data safety and privacy 28:06 Balancing privacy and sharing -- learning about diseases without consequences to the individual 29:00 Sharing public methylation data can help save millions of lives 31:19 Firewalled personal data and medical data -a solution to protect the individual 32:25 Goal: To get the best solutions to prevent anyone to hack the database 33:41 The collaboration between Epi-Age and users 36:41 The best way to use the Epi-Age test 40:25 Transferring the responsibility of health from your doctor to yourself 40:45 Experience as a teacher 41:10 Trial, error, and scientific truth 41:36 Self-empowerment and the biohacking movement 43:22 Technology empowers people about medicine 44:37 epiAge app as a source of information for lifestyle trends 48:11 Environmental influence on genetics 49:38 The impact of your mental environment on your health 50:02 Listen to your own clock Ordering tests: Epi-Age.com Use Promo code Longevity to get 10% off the cost of your test…. Link to Dr Szyf's Ted Talk: https://youtu.be/38OUCtzkT4Q Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

S1 Ep 5Dr Amber ND - Peptide Expert - Mitochondrial Peptides for Ultimate Cellular Energy
Dr. Amber is an A4M trained peptide expert and Naturopathic Doctor practicing out of beautiful California. In this episode we talk about two peptides that address mitochondria and why that's an amazing place to start with peptides. Dr. Amber uses the term "forgot" which you'll learn why towards the end of the show, and how to remind your body of proper signaling and why peptides are so amazing! Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes. 1:30 Why we start with MITOCHONDRIA 2:15 Theory of aging 3:15 A4M 5:25 The issue with the thought of "getting energy from energy drinks" you are an energy factory 6:45 Why issues show up in the brain and heart first 9:00 The link between Fibromyalgia and mitochondrial dysfunction 10:00 Inflammation, why it needs to be addressed first so that one can then add things like peptides to help with repair 11:00 How common analgesics (pain relief pills) negatively affect mitochondria 12:30 How blue light negatively affects melatonin production 13:10 Things that damage the mitochondria. 13:20 How to create new mitochondria 13:45 Why sleep is so important 15:00 Ways to mitigate damage, there are amazing things you can do :) 15:20 Computer software to reduce blue light and protect your eyes and mitochondria 16:30 Offset the positive ions with negative ions by going to a natural body of water or grounding 17:00 Red light can upregulate production of ATP and mitochondria 19:30 Cold water exposure 21:30 Why Nathalie likes cold lakes over a tub 😂 22:15 Our cells make waste naturally, not including environmental factors, that's normal. This is why we need to support detoxification 23:00 Leveraging hormetic stressors. LDN and adaptation principle to your benefit. 23:40 Molecular hydrogen, because we need oxidation, but this works almost like an adaptogen 24:45 HIIT workouts for the win! 25:00 Cell senescence 27:00 SS31 28:20 May be useful for - cardiac issues, insulin/pancreatic dysfunction, depression, fibromyalgia, chronic fatigue, anti-aging. 30:15 Amount needed of SS31. 33:00 Our bodies make these peptides, but often "need instructions" or a reminder... 34:30 How the wrong peptide at the wrong time can do more harm than good, and the right peptide at the right time can really do wonders and promote signaling that the body really needed and "forgot" about. 37:00 Melanotan 39:00 Nutrition is incredibly important, but here's why you often need help from peptides 40:10 5-Amino-1MQ (capsule, no needle use) 41:50 How 5-Amino-1MQ keeps your NAD around longer 42:50 L-carnitine 43:30 Dosing of 5-Amino-1MQ 44:00 How some people react very different, triggering more anxiety 46:00 Sublingual NAD powder that Nathalie loves 47:10 The placebo of peptides and supplements and the power of belief 48:45 The issue with digesting supplements 49:15 Leaky gut 50:30 NAD The patch versus IV, and why you can get more from the patch! 52:30 Kisspeptin peptide, for men vs. women, "kiss-54" "kiss-10" 55:45 Natural increase of testosterone 56:00 Why Dr. Amber uses the term "forgot"...and how to remind your body of proper signaling 57:00 And why you should avoid exogenous testosterone for as long as possible 57:45 Kiss-54 https://www.instagram.com/doctorambernd/ drambernd.com
S1 Ep 3Dr. Elizabeth Yurth Peptide Expert - DSIP Sleep Peptide, Hormones and The Shocking Truth about Melatonin
Dr. Yurth is on the cutting edge helping her clients prevent joint replacement with the use of peptides, hormones and preventative medicine. She's an expert on circadian rhythm and how to fix yours with peptides and other biohacks! Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes. http://boulderlongevity.com/ 3:13 Dr. Yurth Background 12:00 industry is about lifelong learning and questioning what we thought we knew 14:00 Take responsibility for your own 15:00 Why Nathalie and Dr. Yurth would rather spend money on their than a fancy 16:00 How you shouldn't expect a peptide to do ALL of the work for you 19:00 Peptides and your Circadian rhythm and deep and REM sleep. 20:54 The best time to have surgery 22:00 The Clock Gene 22:29 How do we fix the circadian rhythm in you 24:50 How this sleep tracker shows you the impact of your actions 25:50 How to increase deep sleep time "the brain cleanout time" 26:21 If you're frustrated that these biohacks aren't "helping you" 26:10 Sleep quality vs. quantity, and how too much sleep can be bad, and what really matters most 28:55 How DSIP could be better for some people in the morning for sleep that night, and great for some in the evening. 31:50 Muscle building 34:30 The other benefits of melatonin 37:33 Stacking and why you should give something a chance 38:30 Biohacking for night shift workers, must biohack 40:25 Why you should take melatonin, and if you're a slow metabolizer of melatonin listen to this! 46:15 How most disease can be linked back to circadian rhythm 50:39 How being breast fed vs. bottle fed and how timing of feeding affects children 54:30 Neuropathy 56:07 Kidney function 56:24 Fibromyalgia 59:32 Pulsing: turning on, turning off, turning on, turning off 59:55 How long to try a peptide for http://boulderlongevity.com/ https://www.instagram.com/dryurth/

S1 Ep 2Hack Light, Mitigate EMF's to Upgrade Your Health with PrimalHacker Thaddeus Owen
Thaddeus Owen the co founder and owner of PrimalHacker has been deep diving into how light and EMF's affect our health and physiology for almost as long as I've known him. He is a wealth of information on the topic and in this episode we deep dive into the many issues impacting our health and, more importantly what we can do about it. For the most part we stick to easy and free interventions you can apply starting today - and we even mention a peptide in our conversation! PrimalHacker sells a curated selection of items that can help you to live a healthier light life including Blue Blockers, Red Lights and more - all at incredibly affordable prices. PLUS you can use Promo Code NAT10 to get an extra 10% off your entire purchase! Please note that this video is for information purposes only and that none of the information in this video is intended as medical advice. Please consult with your health provider before starting any new intervention and especially if you have a medical condition. Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

S1 Ep 1Peptides for Fat Loss w/ CanLab: Setmelanotide, AOD 9604, FRAG17691, Tesamorelin, CJC 1295 NO Dac
In this Interview, Jean-Francois Tremblay, owner of CanLab and I dig in to one of the new darlings of the peptide world - Tesamorelin and a less known but possibly just as effective other option - Setmelanotide - an offshoot of the better known Melantonan 2. We also cover AOD 9604, FRAG 17691 and CJC1295 ...and why you probably want to avoid the version with DAC (drug affinity complex)... We start with a chat about how if you're after lasting results there's really no way to avoid optimizing your diet, moving more, optimizing sleep etc... but these peptides might just help to speed things along and ease some of the bumps along the way. Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes. Show Notes: Keto Calorie Peptides Help with Fat Loss Body Recomposition Growth Hormone unregulated by Fat Loss peptides like FRAG 17691 or AOD9604 (just one amino acid difference) help to mobilize fatty acids in the fat cell – but need to be in calorie/energy deficit for it to stay out Consistency and sticking to your plan is the ultimate secret sauce… Why Canlab combines Frag and AOD 9604 More about Frag and AOD….are they the same or different? AOD lacks one tyrosine…means that it lasts longer…whereas Frag uses more up front and gets metabolized faster….. Tesamorelin…..what it does…. The skinny on Tesamorelin….it's not about Tesa it's about the growth hormone release…. Re Muscle Gains attributed to Peptides….in studies re old people it's about bringing back muscle you once had…. Hormone replacement therapy is at the foundation of reclaiming muscle mass GH good for muscle sustaining (vs growth) and tissue repair (but doesn't hold a candle to BPC and TB4) Tesamorelin – origins – where it came from originally….very close to CJC 1295 (Mod IGRF 121 is actually CJC 1295 without dac). and other Growth Hormone Secretagogues. The difference between Tesa and CJC not really all that great….why some people may be promoting Tesa over CJC 1295 the magic is in the dose. Difference about with Dac and without Dac. With Dac too many peaks of growth hormone (similar to MK 677….increases risk of insulin resistance…..why is the Dac long lasting…binds to albumin in the blood ….which is problematic as there may have been relationship to blood cancer seen in certain studies….so better to use without DAC…just use multiple times a day if necessary Post workout (3) is a good time…but pre bed(1), pre workout and first thing in the morning (2) are all better Setmelanotide – another derivative of alpha MSH (Melanotan, melanotan 2, PT141) Basically prioritizes appetite suppression over tanning and sexual enhancement..they all create a tan just to varying degrees…. SM get appetite curbing (some sexual stim)…increases metabolic rate by about 6%, without increasing HR or BP…. On average can expect about 1 lb a week fat loss…. Many reports of people using it with good results – safe track record…..Clinical studies went for 12 months Do not start at full dose of 1.5mg a day….start at .5 1-2 days then 1.0mg for a couple of days and then increase to full dose to avoid possible /nausea In studies – they changed nothing else….and saw results but it's likely that as people lost weight they may have started to move more etc… At this point best method for most peptides is SubQ over oral….Intranasal may work but need to use higher dose (aka PT141 1 mg is SubQ and 2mg is IntraNasal) Tesofensine – not a peptide acts on dopamine and AC receptors in the brain so needs to be used with great caution Please note that this video is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your care provider. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition.