JAMA Medical News

Hear the latest on PCSK9 inhibitors, cardiorenal benefits of GLP-1 drugs, and other clinical research in this interview with Katie Berlacher, MD, MS, chair of this year's annual ACC meeting. Related Content: PCSK9 Inhibitors in Diabetes, Tirzepatide's Cardiorenal Effects, Shingles Vaccine, and More From ACC

JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "How mRNA Vaccines Could Help Treat Cancer." Related Content: How mRNA Vaccines Could Help Treat Cancer

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "New Hope for Patients With Advanced Alcohol-Related Cirrhosis Who Stop Drinking." Related Content: New Hope for Patients With Advanced Alcohol-Related Cirrhosis Who Stop Drinking

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "What to Know About the New Lipid Guidelines." Related Content: What to Know About the New Lipid Guidelines

JAMA Medical News Associate Managing Editor Kate Schweitzer and Staff Writer Samantha Anderer discuss "Why the EPA's Reversal on Heavy Metal Air Pollution Is Cause for Concern." Related Content: Why the EPA's Reversal on Heavy Metal Air Pollution Is Cause for Concern

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "After a Decade of Progress Against HIV, PrEP Enters a Precarious Era." Related Content: After a Decade of Progress Against HIV, PrEP Enters a Precarious Era

JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "Are AI Tools Ready to Answer Patients' Questions About Their Medical Care?" Related Content: Are AI Tools Ready to Answer Patients' Questions About Their Medical Care?

JAMA Medical News Associate Managing Editor Kate Schweitzer and Staff Writer Samantha Anderer discuss "In the Low-Carb vs Low-Fat Debate, Study Suggests Food Quality Matters More for Heart Health." Related Content: In the Low-Carb vs Low-Fat Debate, Study Suggests Food Quality Matters More for Heart Health

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "What Nutrition Experts Say About the New Dietary Guidelines for Americans." Related Content: What Nutrition Experts Say About the New Dietary Guidelines for Americans

JAMA Medical News Associate Managing Editor Kate Schweitzer and Lead Senior Staff Writer Rita Rubin discuss "US Patients Getting ICE-d-Out of Health Care." Related Content: US Patients Getting ICEd-Out of Health Care

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Mechanisms Are Emerging for COVID-19 Vaccine−Associated Myocarditis." Related Content: Mechanisms Are Emerging for COVID-19 Vaccine−Associated Myocarditis

JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "Data on 3 New GLP-1 Drugs for Weight Loss That May Be Approved This Year." Related Content: Data on 3 New GLP-1 Drugs for Weight Loss That May Be Approved This Year

In this week's roundup, Associate Managing Editor Kate Schweitzer and Lead Senior Staff Writer Rita Rubin discuss "Stress May Link Depression and Anxiety to Cardiovascular Disease." Related Content: Stress May Link Depression and Anxiety to Cardiovascular Disease

In this week's roundup, JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "What to Know About the Wegovy Pill for Obesity" and more. Related Content: What to Know About the Wegovy Pill for Obesity

In this week's roundup, JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "What to Know About the WHO's New GLP-1 Guideline" and more. Related Content: What to Know About the WHO's New GLP-1 Drug Guideline

In this week's roundup, JAMA Medical News Director Jennifer Abbasi and staff writer Samantha Anderer discuss "Can Nicotine Pouches Help People Quit Smoking?" and more. Related Content: Can Nicotine Pouches Help People Quit Smoking?

In this week's roundup, JAMA Medical News Associate Managing Editor Kate Schweitzer and freelance writer and Harvard medical student Emily Harris discuss "A Growing Movement Aims to Prepare All Physicians to Care for Older Adults" and more. Related Content: A Growing Movement Aims to Prepare All Physicians to Care for Older Adults

In this episode, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Medical News Director Jennifer Abbasi discuss the journal's inaugural Research of the Year roundup. Related Content: Research of the Year 2025

Correction: an earlier version of this podcast misstated the phosphorylated tau analyte measured by the Roche blood biomarker test. It is p-tau181, not p-tau217. In this week's roundup, JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "Alzheimer Disease Blood Test Cleared for Primary Care, but Questions Remain About Its Use" and more. Related Content: Alzheimer Disease Blood Test Cleared for Primary Care, but Questions Remain About Its Use

Updates on coffee and AFib, a polypill approach for HFrEF, the first oral PCSK9 inhibitor, vitamin D supplementation for secondary prevention, and more: Joanna Chikwe, MD, chair of the American Heart Association's Scientific Sessions conference and of the Department of Cardiac Surgery in the Smidt Heart Institute at Cedars-Sinai Medical Center, shares clinical research highlights from the recent meeting. Related Content: Coffee and AFib, Oral PCSK9 Drugs, an HFrEF Polypill, and Vitamin D Post-MI—Highlights From AHA 2025

In this week's roundup, JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "US Governors Are Forming a Public Health Alliance Amid Federal Funding Cuts and Shifting Guidance" and more. Related Content: US Governors Are Forming a Public Health Alliance Amid Federal Funding Cuts and Shifting Guidance

Updates on SGLT2 inhibitors, fish oil and hemodialysis, GLP-1 drugs, and more: Katherine R. Tuttle, MD, education committee co-chair of Kidney Week 2025 and a professor of medicine at the University of Washington, shares clinical research highlights from the recent meeting. Related Content: SGLT2 Inhibitors, Fish Oil in Hemodialysis, GLP-1 Drugs, and More—Highlights From Kidney Week

In this weekly roundup, JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "MASLD—The Chronic Liver Disease That Affects Tens of Millions of US Adults but Flies Under the Radar" and more. Related Content: Metabolic Dysfunction–Associated Steatotic Liver Disease in Adults MASLD—The Chronic Liver Disease That Affects Tens of Millions of US Adults but Flies Under the Radar ------------------------ jamamedicalnews.com

In this weekly roundup, JAMA Medical News Director Jennifer Abbasi and Staff Writer Samantha Anderer discuss "Peanut Allergies Appear to Be on the Decline Following Early Introduction Guidelines" and more. Related Content: Peanut Allergies Appear to Be on the Decline Following Early Introduction Guidelines

Dementia is still a highly stigmatized condition. Nancy Berlinger, PhD, a senior research scholar at The Hastings Center for Bioethics, discusses a new report about the cultural narratives of dementia and how they can affect the quality of life and the care of patients with the condition. Related Content: Living With Dementia Report Emphasizes That Even Those With Advanced Disease Have Stories to Share

State Laws Aim to Bring Internationally Trained Physicians to Underserved Areas, but Barriers Abound; Oral Microbiome Composition Linked to Pancreatic Cancer Risk Related Content: Oral Microbiome Composition Linked to Pancreatic Cancer Risk State Laws Aim to Bring Internationally Trained Physicians to Underserved Areas, but Barriers Abound

A new European Society of Cardiology clinical consensus statement deals with cardiovascular disease prevention and management in COVID-19, including cardiac long COVID. The report's lead author, Vassilios Vassiliou, MBBS, PhD, MA, discusses the guidance and key questions that remain about COVID-19 and the heart. Related Content: New Guidance on Cardiovascular Disease and COVID-19—From Infection to Long COVID to Vaccination

Epidemiologist Brian Lee, PhD, discusses his study on acetaminophen use during pregnancy and children's risk of autism and other neurodevelopmental disorders in this interview with JAMA Deputy Editor Linda Brubaker, MD. Related Content: Acetaminophen Use in Pregnancy—Study Author Explains the Data

Ultraprocessed Foods and Cardiometabolic Health—New Report on a "Growing Public Health Challenge"; New Analysis of Women's Health Initiative Data Aims to "Clear the Air" Over Menopausal Hormone Therapy Related Content: New Analysis of Women's Health Initiative Data Aims to "Clear the Air" Over Menopausal Hormone Therapy Ultraprocessed Foods and Cardiometabolic Health—New Report on a "Growing Public Health Challenge"

Updates on GLP-1 drugs in heart failure, β-blockers after myocardial infarction, the shingles vaccine, and more: Felix Mahfoud, MD, chair of the Department of Cardiology at University Hospital Basel, shares clinical research highlights from the recent European Society of Cardiology Congress. Related Content: GLP-1 Drugs in Heart Failure, β-Blockers After MI, the Shingles Vaccine, and More From ESC 2025

Pulmonologist Michael J. Welsh, MD, is the co-recipient of the 2025 Lasker-DeBakey Clinical Medical Research Award for his research on cystic fibrosis. In this interview, he discusses his early clinical encounters with the disease, the foundational work that led to the lifesaving drug Trikafta, and future directions for cystic fibrosis treatment. Related Content: How Cystic Fibrosis Went From Fatal to Treatable Rewriting the Chapter on Cystic Fibrosis

What Is 7-OH?; Real-World Experience With Antiamyloid Therapies for Alzheimer Disease; FDA Panel on SSRIs and Pregnancy Lacked Nuance, Experts Say Related Content: What to Know About 7-OH, the New Vape Shop Hazard Treating Alzheimer Disease With Antiamyloid Therapies—The Real-World Experience Grows FDA Panel Casts SSRIs During Pregnancy as Risky—Many Experts Disagree

The Effects of Newly Changed Guidance on COVID-19 Shots During Pregnancy; Heart Disease Deaths Have Changed; Progress Toward a Norovirus Vaccine Related Content: The CDC No Longer Recommends COVID-19 Shots During Pregnancy—Now What? New Research Finds Long-Term Shifts in Heart Disease Mortality Is There a Norovirus Vaccine on the Horizon?

In this follow-up to a 2017 interview with JAMA Medical News, the University of Southern California's Maja Matarić, PhD, the computer scientist who pioneered the field of socially assistive robotics, discusses how artificial intelligence is advancing the field in areas ranging from autism to physical rehabilitation to anxiety and depression. Related Content: Social Robots That Help Support People's Health Are Getting a Boost From AI Socially Assistive Robots

Kimmie Ng, MD, MPH, a JAMA associate editor and associate chief of the Division of Gastrointestinal Oncology at the Dana-Farber Cancer Institute, shares highlights from the American Society of Clinical Oncology's annual meeting, including new research on diet, exercise, and cancer survival and the best time of day for treatment. Related Content: Lifestyle and Cancer Survival, the Best Time of Day for Treatment, and More—Highlights From ASCO

New NIH-FDA Partnership Targets Nutrition Research Gaps; First Blood Test for Alzheimer Biomarkers Receives FDA Clearance; A Growing Movement to Care for Caregivers Related Content: New Federal Program Seeks to Bridge Nutrition Research With Regulatory Policy What to Know About the First FDA-Cleared Blood Test for Alzheimer Biomarkers As the US Ages, a Growing Movement Aims to Care for Caregivers

Delaying diagnosis of parkinsonism can mean delaying care. In a study recently published in JAMA Neurology, David Vaillancourt, PhD, and colleagues tested the ability of an AI model to differentiate between Parkinson disease and other neurodegenerative disorders when paired with MRI. He joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH to discuss. Related Content: A Large Proportion of Parkinson Disease Diagnoses Are Wrong—Here's How AI Could Help Automated Imaging Differentiation for Parkinsonism

Federal Funds for Rural Health Care May Be Cut; Why the IV Fluid Shortage After Hurricane Helene Was Years in the Making; Surge in US Sports Betting Raises Public Health Concerns Related Content: Federal Funds for Rural Health Care Are on the Chopping Block—Here's What That Could Mean IV Fluid Shortages Persist Months After Hurricane Helene Hit a Supplier—Hospitals Have Had to Adapt The Hidden Health Costs Associated With Legalized Sports Gambling

Susan Athey, PhD, of Standford University joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss her research on machine learning to target behavioral nudges for college students and their potential implications for health care. Related Content: How an Economist's Application of Machine Learning to Target Nudges Applies to Precision Medicine

Ajay J. Kirtane, MD, SM, a professor of medicine at Columbia University Irving Medical Center, discusses late-breaking clinical research presented at the annual meeting of the American College of Cardiology in an interview with JAMA Medical News Director Jennifer Abbasi. Related Content: Heart Health Highlights From ACC—Marathon Runners and Mortality, Oral GLP-1 Drugs, and More

Axe Falls on Federal Health Workforce; Experts Say CDC Cuts Will Cost Lives Related Content: "Guaranteed Pandemonium" as HHS Secretary Slashes Federal Health Workforce Experts Say Abrupt and "Staggering" CDC Cuts Will Cost Lives

Diabetic retinopathy remains a leading cause of preventable blindness worldwide, and AI may facilitate screening, if such models continue to perform well when they are deployed in the real world. Coauthors Arthur Brant, MD, of Stanford University, and Sunny Virmani, MS, of Google join JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss a new study published in JAMA Network Open. Related Content: Diabetic Retinopathy Is Massively Underscreened—an AI System Could Help Performance of a Deep Learning Diabetic Retinopathy Algorithm in India

A recent study published in JAMA Health Forum suggests that institutions may be able to deploy custom open-source large language models (LLMs) that run locally without sacrificing data privacy or flexibility. Coauthors Thomas A. Buckley, BS, and Arjun K. Manrai, PhD, from the Department of Biomedical Informatics at Harvard Medical School join JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss. Related Content: Can Open-Source AI Models Diagnose Complex Cases as Well as GPT-4?

The US Is Suing Pharmacies for Aiding in the Opioid Crisis; Texas Measles Outbreak Spurs Call for Stronger Vaccine Advocacy; Study Finds Sleep-Related Infant Deaths Are on the Rise Related Content: US Government Sues Pharmacy Chains CVS and Walgreens for Their Alleged Role in the Opioid Epidemic Amid Texas Measles Outbreak, Clinicians Struggle to Offset Increasing Vaccine Hesitancy Amid Decreasing Infant Mortality, Sleep-Related Infant Deaths Are on the Rise

Correction: This podcast has been updated to add additional context on the frequency of false positives. Open neural tube defects affect approximately 1 in 1400 births. Daniel Herman, MD, PhD, of the University of Pennsylvania Perelman School of Medicine joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss a quality improvement study examining the need to continue to incorporate race in tests that screen for these defects. Related Content: Study Findings Question Value of Including Race in Prenatal Screening for Birth Defects Reassessing the Inclusion of Race in Prenatal Screening for Open Neural Tube Defects