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University of California Audio Podcasts (Audio)

University of California Audio Podcasts (Audio)

277 episodes — Page 5 of 6

Overview: PSA Recurrent Prostate Cancer

Experts present new tools for managing PSA-recurrent prostate cancer. Dr. Steven Seyedin describes how PET/CT imaging enhances detection by reducing false positives and improving staging accuracy. Dr. Thomas Hope highlights PSMA PET imaging, now the standard approach, which identifies cancer more precisely by targeting tumor-specific proteins. Dr. Julian Hong discusses stereotactic body radiation therapy (SBRT) for patients with limited metastases, showing that it offers effective, low-toxicity treatment while preserving quality of life. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40867]

Sep 15, 202532 min

Cellular Reprogramming in Human Disease

Deepak Srivastava, MD, explores how cellular reprogramming offers new hope for treating heart disease. He highlights innovative strategies to regenerate damaged heart tissue by stimulating adult cardiomyocytes to divide and converting fibroblasts into heart-like cells. His team develops a nonviral delivery system using lipid nanoparticles and investigates the role of specific gene regulators in restoring heart function in animal models. Srivastava also discusses a potential oral therapy for aortic valve disease, driven by insights into cellular fate changes caused by NOTCH1 mutations and telomere shortening. Additionally, he reveals how trisomy 21 may trigger congenital heart defects by altering the identity of specialized heart cells. Through pioneering research in genetics and regenerative medicine, Srivastava demonstrates how understanding developmental biology can lead to transformative clinical advances. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40447]

Sep 13, 202558 min

Panic!: The Sound of Fury

Film historian Rebecca Prime joins moderator Ross Melnick (Film and Media Studies, UCSB) for a discussion of the classic Hollywood film The Sound of Fury. Prime outlines the film’s production history and how its political and social commentary was shaped by its director, Cy Endfield, who would go on to be blacklisted due to his association with the Communist Party. They further discuss Endfield’s subsequent work in London and how he struggled with the blacklist for the rest of his career. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40919]

Sep 13, 202534 min

Why Research Funding Matters: A Patient Perspective

Kimberly Peters, a stage four uterine cancer patient at UC San Diego Health, urges government leaders not to cut science funding. She warns that reduced federal support risks delaying vital research and life-saving cures. [Health and Medicine] [Show ID: 41071]

Sep 11, 20251 min

Earth Works: The Cultural Evolution of Farm Workers

Explore the evolving identities, histories, and rights of farmworkers across Mexico and the United States. Panelists—including scholars, organizers, and agricultural leaders—discuss cross-border migration, labor conditions, cultural heritage, and the impact of policies on communities. The conversation highlights the role of indigenous and Catholic traditions, the legacy of the Bracero Program, and the continuing struggles and resilience of agricultural workers. It also examines how economic and environmental pressures shape migration, labor organizing, and efforts to create sustainable, dignified livelihoods for future generations. Series: "Future Thought Leaders" [Public Affairs] [Agriculture] [Business] [Show ID: 40584]

Sep 9, 20251h 37m

Bach Lives!

Considered the godfather of A.I. music, UC Santa Cruz professor and composer David Cope, who died in May, 2025, developed the computer program EMI, or Experiments in Musical Intelligence, in the 1980s. It was one of the earliest computer algorithms used to generate classical music. This documentary film by UC Santa Cruz's Bob Giges looks at the impact of Cope's genius on the world of music. Series: "Arts Channel " [Science] [Arts and Music] [Show ID: 40968]

Sep 9, 202525 min

Treatment of Advanced Prostate Cancer

Experts from UCSF outline the latest treatments and research for advanced prostate cancer, highlighting improved outcomes and promising therapies. Dr. Kelly Fitzgerald reviews intensified androgen deprivation therapy (ADT) and the evolving role of imaging, triplet therapy, and local treatments. Dr. Ivan de Kouchkovsky shares how radioligand therapies like Lutetium-177 PSMA target cancer with precision and are now approved earlier in care. Dr. David Oh explains immunotherapy strategies, including cancer vaccines and checkpoint inhibitors, and explores new options like bispecific T-cell engagers. Dr. Terry Friedlander discusses bone health and the impact of hormone therapy, offering strategies to reduce fracture risk and improve quality of life. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40868]

Sep 8, 202553 min

One Doctor's Journey Through the AIDS Epidemic

On his very first day at San Francisco General Hospital, Dr. Paul Volberding met his first AIDS patient – a moment that shaped his career and left an indelible mark on the fight against an epidemic. Now, more than 40 years later, Volberding reflects on the creation of Ward 86, the nation’s first HIV clinics, and how UCSF’s compassionate, community-first approach redefined HIV/AIDS care worldwide. The work of Volberding and UCSF’s dedicated clinicians and scientists laid the foundation for advancements that continue to save lives today. [Health and Medicine] [Show ID: 40986]

Sep 8, 20257 min

Neuromodulation Pharmacogenetics and Imaging: Biological Approaches to Tailoring Therapy

As part of the 2025 Developmental Disabilities Conference, Dr. Elysa Marco talks about various biological approaches to therapy. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40623]

Sep 7, 202542 min

The Exploration of Space Asteroids: The Fossils of the Universe

Asteroids, often called “fossils of the solar system,” are remnants from its formation that offer clues about planetary origins and the potential beginnings of life. Dr. Neil Farber, Solar System Ambassador for NASA’s Jet Propulsion Laboratory, explains that some, known as near-Earth objects, pose impact risks—though large, dangerous collisions are rare—and NASA’s Near-Earth Object Surveyor mission aims to detect and track them to inform planetary defense strategies. Asteroids may also hold resources, such as metals or water, that could one day support space exploration, though current technology limits mining feasibility. Recent missions like OSIRIS-REx, Lucy, and Psyche are expanding our understanding of asteroid composition, history, and diversity, with findings including evidence of past water, amino acids, and nucleotide bases—key building blocks of life—raising intriguing questions about whether asteroids helped seed life on Earth. Series: "Osher UC San Diego Distinguished Lecture Series" [Science] [Show ID: 40964]

Sep 6, 202549 min

CWC Docs: American Homeboy

Documentary subject and Chicano activist Jerry Ramirez joins moderator Clint Terrell (English, UCSB) for a discussion of the documentary film American Homeboy. They discuss Ramirez’s involvement with the film, his relationship to his Chicano identity, and how his experience being incarcerated fueled his activism, particularly in relation to Chicano issues. Ramirez and Terrrell reflect on how the film portrays Chicano history, including how Chicana and Chicano identity has been shaped over time. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40921]

Sep 6, 202540 min

This Fungus Turns Food Waste Into Cuisine

Chef-turned-chemist Vayu Hill-Maini has a passion: to turn food waste into culinary treats using a fungus called Neurospora intermedia. Visit the postdoctoral researcher in the lab and in the kitchen to learn how this mold could make our food system more sustainable and delicious. Series: "UC Berkeley News" [Science] [Show ID: 40983]

Sep 5, 20253 min

Day in the Life of a Professional Photographer

Join Greg, UC Davis staff photographer, as he embarks on an 8 a.m. (or rather, 5 a.m.) photoshoot! Get a behind-the-scenes look at being a university photographer, capturing moments around campus and waking up at ungodly hours to get the perfect shot. With a whistle and a witty joke, Greg explains what it means to take professional photos. Series: "UC Davis News" [Arts and Music] [Show ID: 41051]

Sep 3, 20253 min

Sibling Support and Developmental Disabilities

As part of the 2025 Developmental Disabilities Conference, Emily Hill talks about how sibling support can be a catalyst for family empowerment. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40622]

Sep 1, 202541 min

Supported Healthcare Decision-Making for People with Developmental Disabilities

As part of the 2025 Developmental Disabilities Conference, Judy Mark, Vivian Do, Miguel Lugo, all from Disability Voices United, talk about supported decision-making in healthcare. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40611]

Aug 31, 202539 min

Active Surveillance for Early-Stage Prostate Cancer

Urologic oncologist Dr. Peter Carroll presents the latest research on active surveillance as a preferred approach for managing low-risk prostate cancer and selected cases of intermediate-risk disease. Drawing from two decades of UCSF data, he explains how long-term outcomes support the safety and effectiveness of delaying treatment for carefully monitored patients. Carroll emphasizes that surveillance decisions should be guided by MRI imaging, PSA density, cancer volume, histologic subtype, and genomic testing. He notes that while many men experience gradual changes over time, only a small percentage require immediate treatment. Carroll also discusses innovations such as AI-assisted pathology and risk profiling to reduce unnecessary procedures. His data-driven approach offers patients a personalized path that preserves quality of life without compromising outcomes. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40801]

Aug 30, 202514 min

Righting Wrong When Sorry Isn’t Enough: Constructing an Asian American Theology of Reparations with Grace Yia-Hei Kao

How should federal governments attempt to right, or at least remedy, past wrongs? Is it appropriate for victims of group-based harms or their descendants to press current generations to atone for the sins of their predecessors? Grace Kao, Professor of Ethics and the inaugural Sano Chair in Pacific and Asian American Theology at Claremont School of Theology, explores these questions by drawing upon the emerging human rights standard for reparations, theological resources from her Presbyterian faith tradition, and four case-studies of acknowledged wrongdoing against AAPI communities. Series: "Ethics, Religion and Public Life: Walter H. Capps Center Series" [Public Affairs] [Humanities] [Show ID: 40876]

Aug 30, 202549 min

Stem Cells and Next Generation Regenerative Medicine Therapies - Medicine Informing Novel Discoveries (MIND)

Hear about cutting-edge advances in regenerative medicine, from lab breakthroughs to patient impact. Catriona Jamieson, MD, PhD, introduces efforts at the Sanford Stem Cell Institute to develop therapies that enhance the body’s ability to heal itself. Dan Kaufman, MD, PhD, shares progress in cancer immunotherapy using engineered natural killer cells derived from pluripotent stem cells. Karen Christman, PhD, explains how her team creates injectable hydrogels from pig heart tissue to support heart repair and regeneration after a heart attack. Tiffani Manolis highlights industry support for making cell and gene therapies more accessible. Patient advocate Justin Graves describes his life-changing experience receiving a stem cell-based therapy for epilepsy, underscoring the real-world promise of these innovations. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40705]

Aug 26, 202559 min

Save Our Humanity

On this glorious evening flight captured by astronauts abroad the ISS, we see Earth in all her glory with clouds, night lights and shimmering Aurora. The music is composed and sung by Samantha Tauber, aka VNCCII, who shares her message of hope and love for Earth. Like the astronauts, we must learn to see Earth as a whole, and do the serious work to care for our home and for our future, with hope and love. Series: "Earth Serenade" [Arts and Music] [Show ID: 40990]

Aug 26, 20255 min

Reproductive Immunology

Ina Stelzer, Ph.D., explores how the maternal immune system adapts to support a healthy pregnancy and how disruptions can lead to complications like preterm birth. Her lab identifies early immune changes linked to spontaneous preterm birth and investigates the role of the maternal brain in regulating immune responses. Stelzer uses advanced technologies like mass cytometry and spatial proteomics to map immune and molecular changes in pregnancy, integrating these data with transcriptomics and mouse models. Her team studies how antidepressants affect immune signaling during pregnancy and examines the impact of social and behavioral factors. These insights may reveal biomarkers and therapeutic targets for improving maternal and fetal health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40773]

Aug 25, 20255 min

Introduction to Prostate Cancer

Prostate cancer remains the most commonly diagnosed cancer and second leading cause of cancer death among men in the U.S., with evolving screening and treatment practices reshaping care in 2025. Dr. Cornelia Ding explains how to read and understand a prostate cancer pathology report by breaking down its five key sections. Dr. Rahul Aggarwal explores how clinical trials improve prostate cancer care by advancing personalized treatment, increasing access, and correcting misconceptions about placebos. Dr. Jonathan Chou highlights the expanding role of precision medicine and how genetic insights guide individualized treatment based on each tumor’s molecular makeup. Dr. Eric Small explains how androgen deprivation therapy (ADT) targets the cancer’s dependence on testosterone and how newer therapies and combinations are improving outcomes, while also emphasizing the need to balance effectiveness with side effects through shared decision-making. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40865]

Aug 25, 20251h 7m

More on Localized Prostate Cancer

UCSF experts present four major approaches to managing prostate cancer, each tailored to disease risk and patient needs. Dr. Peter Carroll explains how active surveillance uses MRI, PSA, and genomic testing to safely delay treatment in low-risk cases while preserving quality of life. Dr. Samuel Washington details prostatectomy, highlighting robotic-assisted surgery’s precision and its impact on recovery, fertility, and sexual function. Dr. Julian Hong outlines radiation therapy options like SBRT and brachytherapy, emphasizing targeted delivery to limit side effects and the importance of ongoing follow-up. Dr. Hao Nguyen introduces focal therapy, which treats only the tumor using techniques like cryotherapy or high-intensity ultrasound, helping patients avoid surgery or radiation while maintaining function and quality of life. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40866]

Aug 25, 202557 min

Panic!: Hedwig and the Angry Inch

Over 20 years since its release, Hedwig and the Angry Inch remains as relevant as ever to the politics of the day. A child of division, Hedwig refuses to be caught between categories, instead evading gender description and embracing herself as lovingly as one can. Writer/director/actor John Cameron Mitchell joins moderator Patrice Petro, Dick Wolf Director of the Carsey-Wolf Center, to discuss a post-screening of Hedwig and the Angry Inch. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40922]

Aug 23, 202559 min

Glycobiology (GLOW)

Amanda Lewis, Ph.D. investigates how glycan-degrading enzymes contribute to bacterial vaginosis (BV), a common condition linked to infertility, preterm birth, pelvic inflammatory disease, and increased cancer risk. Her research shows that BV-associated bacteria strip protective sugar coatings—glycans—from vaginal epithelial cells, disrupting normal function and increasing vulnerability to infection. Lewis and her team study specific enzymes, such as sialidases, that remove sialic acid from glycoproteins and mucins. Using clinical samples and imaging techniques, they identify how these changes in glycan composition correlate with disease severity. Their work reveals how glycan degradation contributes to persistent or recurrent BV and opens new pathways for understanding the microbiome's role in women’s health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40678]

Aug 22, 202513 min

Intermittent Fasting: A Strategy To Prevent Cardiometabolic Diseases And Promote Healthy Aging

Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., explores the science and clinical evidence behind intermittent fasting and its role in promoting cardiometabolic health. He explains how aligning eating patterns with the body’s natural circadian rhythms can improve weight, blood pressure, glucose regulation, and other risk factors, especially in individuals with metabolic syndrome or type 2 diabetes. Wilkinson highlights promising results from time-restricted eating studies conducted in collaboration with UC San Diego and the Salk Institute, where narrowing the daily eating window led to improved metabolic markers and potential benefits beyond weight loss. He also outlines practical tips for safely adopting this lifestyle approach and stresses the importance of ongoing research. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40319]

Aug 22, 202554 min

Bach and Earth – Five Beautiful Movements

Organist Brian Hoffman performs Bach’s Canonic Variations (BWV 769), Vom Himmel hoch da komm' ich her (“From Heaven Above to Earth I Come”), in this masterful recording. To accompany the music, we revisit stunning Earth photography drawn from 50 Earth Serenade films featuring views of the Caribbean, the Sahara, the Aurora, the Pacific, and breathtaking sunsets. Together, the music and images celebrate both heavenly inspiration and earthly beauty. Series: "Earth Serenade" [Arts and Music] [Show ID: 40989]

Aug 21, 202512 min

Immunotherapy and Prostate Cancer

Immunotherapy expert Dr. David Oh explains how the immune system can be trained to recognize and fight prostate cancer. He outlines key immune players—dendritic cells and T cells—and describes how immunotherapies target different stages of their interaction with tumors. Oh highlights FDA-approved treatments such as Provenge, a vaccine made from a patient’s own cells, and PD-1 checkpoint inhibitors for patients with specific genetic mutations like microsatellite instability. He also discusses potential autoimmune side effects and emphasizes the importance of genetic testing. Looking ahead, he introduces bispecific T-cell engagers, experimental therapies that physically link T cells to tumors, triggering an immune attack. These promising treatments offer new hope, especially for men with advanced, treatment-resistant prostate cancer. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40811]

Aug 21, 202511 min

A Closer Look at…Genetic Medicine and Artificial Intelligence

AI and genetic medicine are converging to transform how we diagnose, treat, and prevent disease. Gene Yeo, Ph.D., unites RNA biology with artificial intelligence to speed the path from genome sequencing to personalized RNA therapeutics. Advances in sequencing have reduced costs dramatically, making interpretation and translation into treatments the real challenge. Using deep learning and large datasets of RNA-binding proteins, Yeo predicts disease vulnerabilities and identifies therapeutic targets, including in neurodegeneration and muscular diseases. Alexis Komor, Ph.D., focuses on DNA, explaining human genetic variation—particularly single-nucleotide variants—and how genome editing technologies like CRISPR can target them. She highlights strategies to correct harmful mutations and explores precise, programmable interventions. Together, their research drives discovery and enables more effective, personalized therapies. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40459]

Aug 19, 202557 min

Radiation Therapy for Localized Prostate Cancer

Radiation oncologist Dr. Julian Hong explains how radiation therapy works and its central role in treating prostate cancer, both when the disease is localized and when it has spread to limited areas. He outlines major radiation options, including external beam radiation, stereotactic body radiation therapy (SBRT), and brachytherapy, and describes how treatment plans are carefully tailored using imaging, planning scans, and computer modeling to maximize precision and minimize side effects. Hong highlights advances in targeting and beam modulation, which allow for safer, more effective treatment. He also discusses typical timelines for treatment, short- and long-term side effects, and the importance of ongoing follow-up to manage late effects of therapy. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40803]

Aug 18, 202513 min

Supporting Immigrant Children with Special Health Care Needs

As part of the 2025 Developmental Disabilities Conference, Dr. Raul Gutierrez, Associate Professor of Pediatrics at San Francisco General Hospital, talks about supporting immigrant children. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40619]

Aug 18, 202539 min

Imaging in Gynecologic Disorders

Rebecca Rakow Penner, M.D., Ph.D., is a body and breast imaging radiologist and MRI physicist advancing how pelvic pain and gynecologic cancers are diagnosed through imaging. She highlights how MRI is improving the detection of endometriosis, pelvic adhesions, venous disorders, and pelvic floor dysfunction with enhanced resolution and motion-sensitive techniques. Rakow Penner also works on new MRI-based protocols that may reduce the need for contrast agents in evaluating breast and ovarian cancer. Through innovative modeling techniques like restriction spectrum imaging, she explores how to differentiate cancerous tissue from post-treatment effects, aiming to improve treatment assessment for cervical and ovarian cancer. Her collaborations span clinical, engineering, and pathology teams. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40673]

Aug 18, 202514 min

Archives of Anonymous Labor: From Farce to Liberation

Film curators Michelle Baroody and Maggie Hennefeld join moderator Patrice Petro for a discussion of their program “Archives of Anonymous Labor: From Farce to Liberation.” The program juxtaposes five films that about anonymity and labor, from silent films that show the invisible labor of housemaids and film editors to films that highlight the erased labor of decolonial struggle. This program is part of the Carsey-Wolf Center annual conference Anonymous Labor in Film and Media. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40920]

Aug 16, 202553 min

Managing Obesity with New Medications

Dr. Robert Baron explores current strategies for treating obesity, emphasizing evidence-based approaches to diagnosis, lifestyle change, medication, and long-term weight maintenance. He explains the limitations of body mass index (BMI) as a diagnostic tool and highlights the importance of assessing both excess fat and its health consequences. He reviews dietary principles, including calorie reduction, avoiding added sugars, and the importance of sustainable habits over specific diet types. He also discusses the role of physical activity—particularly strength training—for preserving muscle and improving long-term outcomes. Baron evaluates weight loss medications such as semaglutide and tirzepatide, noting their benefits, side effects, and the need for continued use to maintain weight loss. [Health and Medicine] [Show ID: 40757]

Aug 15, 202557 min

Glory of Lights

We travel abroad the ISS at with these images of Europe to the Red Sea at night. The music is the wonferfully joyous Sinfonia from Bach’s Cantata 29, performed by organist David von Behren at First Plymouth Church in Lincoln, Nebraska. Series: "Earth Serenade" [Arts and Music] [Show ID: 40988]

Aug 14, 20254 min

Enhancing the Health of Adults with Disabilities in Community Fitness Facilities

As part of the 2025 Developmental Disabilities Conference, Allen Friedland, Terri Hancharick and Jack Jadach talk about a collaborative approach to enhancing health in fitness centers. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40613]

Aug 13, 202534 min

Panic!: CBS and the 1950s Blacklist

Carol Stabile (Clark Honors College, University of Oregon) joins moderator Patrice Petro for a discussion of “CBS and the 1950s Blacklist,” a program that included an episode of the television sitcom The Goldbergs and William N. Robson’s radio broadcast titled “Open Letter on Race Hatred.” They discuss the history of anti-communist activism in the U.S. and how CBS capitulated to the FBI and its blacklisting campaign. Stabile also outlines how the FBI targeted public intellectuals and artists. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 40918]

Aug 9, 202544 min

Managing Diabetes

Dr. Robert Baron outlines major updates in type 2 diabetes care, emphasizing that blood sugar control alone does not significantly reduce cardiovascular risk, though it helps prevent microvascular complications. New guidelines now prioritize medications with proven cardiovascular and kidney benefits—GLP-1 receptor agonists and SGLT2 inhibitors—over traditional first-line therapy like metformin. Baron explains how these newer drugs not only lower blood sugar but also reduce the risk of heart attack, stroke, kidney disease, and heart failure, with added benefits such as weight loss. He also covers changes in screening, diagnosis, blood pressure goals, and individualized treatment strategies based on age, comorbidities, and patient preferences. [Health and Medicine] [Show ID: 40756]

Aug 8, 202557 min

Typhoon Mysteries

Nature's fury can be devastating on Earth. Typhoon Nepartak over the South China Sea in 2016 caused severe damage and deaths in China, Taiwan and the Phillipines. Yet seen from the International Space Station, the typhoon looks surprisingly serene. These artfully photographed images from astronauts aboard ISS 48 are set to the music of Catherine Brisset and her cristal Baschet, a unique glass keyboard with fanciful metal shapes to help the mysterious sounds resonate. Brisset plays a variation on Bach’s Sonata #2, the Grave movement, with such subtle and emotive touch. Series: "Arts Channel " [Arts and Music] [Show ID: 40977]

Aug 7, 20254 min

Alzheimer's Disease in Women: Why Sex Differences Matter

Sarah Banks, Ph.D. explores why Alzheimer's disease affects women differently than men, emphasizing distinct patterns in tau pathology, cognitive testing bias, and treatment response. She explains how women tend to show a rapid buildup of tau during early cognitive decline, which may contribute to their higher prevalence of Alzheimer's. Banks also highlights how common diagnostic tools may overlook symptoms in women and how approved treatments may offer less benefit for them. Her research at UC San Diego investigates key sex-based differences in risk factors, including sleep apnea, diabetes, and exercise. One study reveals that over 70% of participating women had undiagnosed sleep apnea. Another focuses on Black women, using blood biomarkers to identify overlooked risks and improve care. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40768]

Aug 7, 20255 min

The Times of Possibility

Legal scholar Annabel Brett explores the idea of “moral possibility”—the boundary between what laws demand and what people can realistically or ethically be expected to do. Drawing from early modern thinkers like Aquinas, Suarez, and Hobbes, Brett shows how moral impossibility has long shaped debates about legal obligation, resistance, and political agency. Commentators Melissa Lane and David Dyzenhaus join the discussion, examining how this concept applies to everything from climate action and military conscription to unjust regimes and democratic norms. Together, they highlight how institutions, customs, and time shape the space between legal duty and human capacity—and why recognizing this gap is vital to both justice and legitimacy. Series: "UC Berkeley Graduate Lectures" [Public Affairs] [Humanities] [Show ID: 40431]

Aug 5, 20251h 43m

Radioligand Therapy for Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Dr. Ivan de Kouchkovsky explains how radioligand therapy delivers targeted radiation to prostate cancer cells using a radioactive isotope attached to a molecule that binds to PSMA, a protein commonly expressed in these tumors. He reviews key clinical trials showing how the therapy improves survival and quality of life for men with metastatic castration-resistant prostate cancer, both after and before chemotherapy. The FDA now approves this approach for patients who have progressed on hormone therapy, even if they haven’t yet received chemotherapy. De Kouchkovsky also highlights efforts to enhance effectiveness by combining therapies, increasing radiation dose, and targeting resistant or PSMA-negative cells. Diagnostic imaging plays a critical role in selecting patients most likely to benefit from treatment. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40810]

Aug 4, 202511 min

The MOM-Health Study and the Multi-Omics for Health and Disease (MOHD) Consortium

Marni Jacobs, Ph.D., M.P.H., presents the MOM Health Study, part of the NIH's Multi-Omics for Health and Disease (MOHD) Consortium, which investigates hypertensive disorders of pregnancy—such as preeclampsia—and their impact on postpartum health. The study aims to uncover the biological mechanisms linking these conditions to long-term maternal outcomes like stroke and heart disease. Unlike other disease sites, participants are enrolled before outcomes are known, allowing researchers to track 750 pregnancies through delivery and one year postpartum. Data collection includes surveys, biospecimens, placental tissue, and continuous blood pressure monitoring. By integrating clinical, environmental, and molecular data, the study supports early detection strategies and collaborative research to improve maternal health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40671]

Aug 4, 20259 min

Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP)

Louise Laurent, M.D., Ph.D., presents new insights into placental biology using cutting-edge molecular and imaging technologies. As part of the NIH-funded Human Biomolecular Atlas Program, her research focuses on mapping the structure and function of the placenta across gestation. By combining bulk RNA sequencing, single-cell analysis, spatial transcriptomics, and imaging mass cytometry, Laurent and collaborators identify key differences in cell types and gene expression associated with pregnancy stages and labor. Her team highlights how specific cells like syncytiotrophoblasts and extravillous trophoblasts evolve over time and interact with maternal tissue. This integrated approach offers an unprecedented view of placental development and lays the groundwork for understanding reproductive health and disease. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40670]

Aug 4, 202519 min

Eat Smart Move More: 5 Takeaways for Prostate Cancer Health

UCSF researchers June Chan and Stacey Kenfield share evidence-based strategies for improving prostate cancer outcomes through exercise and diet. They highlight studies showing that physical activity—including resistance and high-intensity interval training—is linked to lower risk of prostate cancer progression and death. They discuss plant-based diets, dietary indices, and specific foods like tomatoes, fish, and nuts, along with the benefits of substituting plant oils for butter. Their analysis includes findings on racial disparities and underscores the need for inclusive research. They also describe current clinical trials exploring lifestyle tools and offer guidance on navigating diet and exercise choices during cancer survivorship. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40808]

Aug 3, 202533 min

Times of Change: Possibility Virtue and a Democratic Politics of Time

Political theorist Annabel Brett of Cambridge University explores how the concept of “moral possibility” shapes law, politics, and public obligation. She explains that laws must be realistic for people to follow—what is morally possible varies by individual, culture, time, and circumstance. Drawing on early modern Catholic legal theory, Brett discusses how extreme demands (like enduring war or plague) may justify higher expectations, but only temporarily. She examines how colonial Spanish officials misused this framework to justify forced labor in Peru, wrongly claiming it aligned with indigenous customs. Brett contrasts this with more democratic approaches to law, like Domingo de Soto’s defense of beggars’ rights, which take individuals’ real conditions seriously. Ultimately, she shows how moral possibility is deeply tied to time, virtue, and justice. Commentary is provided by David Dyzenhaus of the University of Toronto. Series: "UC Berkeley Graduate Lectures" [Public Affairs] [Humanities] [Show ID: 40430]

Aug 2, 20251h 58m

Managing Lipid Disorders Like High Cholesterol

Dr. Robert Baron reviews best practices in lipid management for preventing cardiovascular disease, with a focus on statin use. He outlines the strong evidence for statins in reducing heart attack and stroke risk by 25–33%, particularly in patients with clinical atherosclerotic disease, diabetes, or high LDL. He explains why shared decision-making is key in primary prevention, where guidelines vary and risk thresholds are debated. Baron discusses the shift to the newer PREVENT risk calculator, which offers improved accuracy and removes race as a factor. He also explains when additional lipid-lowering medications may be appropriate and clarifies the impact of risk-enhancing factors like family history, coronary artery calcium, and LP(a). [Health and Medicine] [Show ID: 40755]

Aug 1, 202558 min

Managing ADT-Related Adverse Effects of Prostate Cancer

Dr. Michael Rabow, a palliative care physician, explores the wide-ranging side effects of androgen deprivation therapy (ADT) for prostate cancer and emphasizes strategies to reduce harm while improving quality of life. He outlines cardiovascular, hormonal, and emotional risks—including heart disease, osteoporosis, depression, and loss of vitality—and explains how early assessment and monitoring can help manage these effects. Dr. Rabow highlights evidence-based interventions such as physical activity and cognitive behavioral therapy (CBT), both of which improve symptoms like fatigue, sexual dysfunction, and emotional distress. He also reviews pharmacological options and stresses the importance of personalized, team-based care and shared decision-making over time. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40815]

Jul 31, 202518 min

River Journeys

Rivers shape the Earth, and music shapes our soul. In this lovely, serene flight aboard the ISS, we trace the sinuous paths of inter-playing rivers, from inland North America to the Gulf of Mexico. Sit back and enjoy the journey, with music by Nathan Gunn. Series: "Arts Channel " [Arts and Music] [Show ID: 40973]

Jul 31, 20254 min

Adaptive/Para Sports for Children and Adolescents with Physical and Developmental Disabilities

As part of the 2025 Developmental Disabilities Conference, Dr. Mary Dubon of Harvard Medical School talk about adaptive and para sports for youth with physical and developmental disabilities. Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 40617]

Jul 30, 202536 min

Human Milk Institute (HMI)

Lars Bode, Ph.D., presents the Human Milk Institute at UC San Diego, the world’s first research center dedicated entirely to human milk. Established in 2022, the institute connects molecular research with clinical practice, community outreach, and public health. It unites multiple programs under one umbrella, including a milk bank for preterm infants, a biorepository, lactation education, and a rapid response team that helped inform WHO breastfeeding guidelines during COVID-19. The institute promotes collaboration across disciplines such as biology, engineering, social science, and public health. Through initiatives like the Human Milk Analytics Core, it advances maternal and infant health while highlighting the broader public health importance of breastfeeding. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40770]

Jul 28, 20256 min