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Show Notes
Dr. Matt Kaeberlein is one of the world’s most respected scientists in the field of aging biology. In this episode, we unpack the real science of longevity — from mTOR inhibition and rapamycin to calorie restriction, biomarkers of aging, and what most people get wrong about lifespan vs healthspan.
We go beyond the hype to ask: What actually works? What’s still theoretical? And where is the frontier of human aging research heading?
Topics we cover:
The biology of aging: mTOR, autophagy, senescence
Rapamycin in humans: What we know and don’t
Why extending healthspan matters more than living longer
Matt’s views on supplements, diet, and biomarkers
The most misunderstood concepts in anti-aging
Referenced studies include:
Dog Aging Project
Interventions Testing Program
Rapamycin human trial data
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