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Science TLDR

Science TLDR

Raymond Ruff

83 episodesEN

Show overview

Science TLDR has been publishing since 2024, and across the 2 years since has built a catalogue of 83 episodes. That works out to roughly 25 hours of audio in total. Releases follow a fortnightly cadence.

Episodes typically run ten to twenty minutes — most land between 13 min and 21 min — though episode length varies meaningfully from one episode to the next. None of the episodes are flagged explicit by the publisher. It is catalogued as a EN-language Science show.

The show is actively publishing — the most recent episode landed 3 weeks ago, with 22 episodes already out so far this year. The busiest year was 2025, with 47 episodes published. Published by Raymond Ruff.

Episodes
83
Running
2024–2026 · 2y
Median length
17 min
Cadence
Fortnightly

From the publisher

Ten-minute paper summaries for scientists and experts.Two episodes a week: Mondays feature the top-scoring paper from a curated weekly digest of T cell engager, bispecific antibody, and protein engineering literature. Fridays cover the top trending paper on PubMed — any field, whatever's catching the research community's attention that week.Hosted by Raymond Ruff, a protein scientist working in translational immunotherapeutics. Audio is generated with NotebookLM; the host prompt aims for measured scientific skepticism rather than hype.Feedback and paper suggestions: [email protected]

Latest Episodes

View all 83 episodes

Episode 81: A blinded, prospective benchmark of in silico antibody discovery anchored to experimental affinity and developability

Aug 25, 202623 min

Episode 80: Trending — Educational expansion and the hidden reversal of the Flynn effect—Differential trends across socioeconomic strata

Jul 22, 202615 min

Episode 79: Trending — Probability of a timely vocal response in mother-infant interaction and later psychiatric diagnosis: A case-control study

Jul 16, 202621 min

Episode 78: Covalently PD‐L1 Anchoring Drives Bispecific Nanostructure Assembly for Spatial Control of T Cell Recruitment and Activation

Jul 6, 202621 min

Episode 77: Trending — People prefer to negotiate with women, even when outcomes are identical and gender is unknown

Jun 26, 202619 min

Episode 76: Combination therapy with a novel CD2-targeted costimulatory bispecific antibody overcomes limitations of CD3 T cell engager treatment for solid tumors

Jun 15, 202620 min

Episode 75: Trending — A 5.3-million-year-old deep-sea whale necropolis in the Diamantina Zone

Jun 12, 202618 min

Episode 74: Discovery of TCR-like antibodies to the KRAS G12D neoantigen via in silico-in vitro workflow

Jun 9, 202611 min

Episode 73: Trending — Work from Home and Disability Employment

Jun 5, 202622 min

Episode 72: From free speech advocates to critics: The Trump administration’s new rhetoric promotes support for censorship among Trump voters

Jun 2, 202619 min

Episode 71: MAGE-A4/MAGE-A8-targeted TCR-based bispecific T cell engager in recurrent and/or refractory solid tumors: a phase 1 trial

Jun 1, 202622 min

Episode 70: Language Modeling Materializes a World Model of Protein Biology

May 27, 202619 min

Episode 69: Novel bispecific T-cell engagers overcoming acquired EGFR resistance

May 25, 202621 min

Episode 68: The lived experience of rejection sensitivity in ADHD - A qualitative exploration

May 22, 202623 min

Episode 67: Deep peptide recognition profiling decodes TCR specificity and enables disease-associated antigen discovery

May 18, 202621 min

Episode 66: The political polarization of health outcomes in the USA

May 15, 202619 min

Episode 65: Enable CAR T cell immunotherapy in glioblastoma by modifying its microenvironment via oncolytic adenovirus encoding bispecific T cell engager

May 11, 202621 min

Episode 64: Climate-driven depopulation and adaptation realities in America’s coastal ground zero

May 8, 202623 min

Episode 63: Engineering of acidic pH-responsive anti-CD3 binding antibodies

May 4, 202621 min

Episode 62: Impact of high-power short-duration atrial fibrillation ablation technique on the incidence of silent cerebral embolism: a prospective randomized controlled study

May 1, 202623 min
Raymond Ruff 2023