New Books in Biology and Evolution

Nicolas Rasmussen‘s new book maps the intersection of biotechnology and the business world in the last decades of the twentieth century. Gene Jockeys: Life Science and the Rise of Biotech Enterprise (Johns Hopkins University Press, 2014) takes readers into the fascinating world of entrepreneur-biologists as they developed five of the first products of genetic engineering. Based on a documentary archive that includes oral history interviews and corporate documents resulting from patent litigation, Rasmussen’s book emphasizes the agency of the biologists in in driving the development of first-generation recombinant DNA drugs like insulin, human growth hormone, and interferon. After an introduction to the development of basic molecular biology in a Cold War context – and paying special attention to the ways that Kuhn’s notion of “normal science” helped shape the discipline – the ensuing chapters each present a case study that illustrates an important aspect of the history of biotech’s rise as manifest in laboratories, courtrooms, universities, freezers, markets, and the public arena. Gene Jockeys closes with a chapter that considers the policy lessons that can be taken from this story. Learn more about your ad choices. Visit megaphone.fm/adchoices

Astrobiology: An Evolutionary Approach (CRC Press, 2014) is a new volume edited by Dr. Vera Kolb that brings together 37 authors from a variety of different research backgrounds to introduce this rapidly developing interdisciplinary field. Anyone coming to the book with questions about the origin or possible manifestations of life... Learn more about your ad choices. Visit megaphone.fm/adchoices

“In a sense, all life consists of the colonization of an electric world. But to see that, we have to go back to the very beginning.” William J. Turkel‘s new book traces the emergence and inhabiting of an electric world through the span of human history and beyond. Embracing a “big history” approach to the archive, Spark from the Deep: How Shocking Experiments with Strongly Electric Fish Powered Scientific Discovery (Johns Hopkins University Press, 2013) is a story of the human understanding and use of electricity through the study of strongly-electric catfish, rays, and eels. It’s a history of intimacy between life and the electric, humans and instruments, life and death, from the earliest history of human interaction with strongly electric fish through the modern world. Turkel collects a fascinating set of sources and stories on therapeutic, experimental, and conceptual encounters with fish as apparatus, and readers will find wonderful engagements with the work of Darwin, Volta, Galvani, von Humboldt, Faraday, Du Bois-Reymond, and many more writers and thinkers. Spark from the Deep is also the result of a very inventive and thoughtful approach to digital history, and we talk about Turkel’s research methodology and engagement with digital tools and sources in the course of the interview. As a result, this will be of interest to listeners who seek stories of the electric, as well as listeners interested more broadly in the craft of history. Enjoy! You can find Turkel’s introduction to doing research with digital sources on his website. Learn more about your ad choices. Visit megaphone.fm/adchoices

David Wright‘s 2011 book Downs: The History of a Disability (Oxford University Press, 2011), offers readers a history that stretches far beyond the strictly defined genetic disorder that is its namesake. Wright shows us how the condition that came to be known as Down’s syndrome has as much to do with the social history of what was called ‘idiocy’ in Early Modern times and reform movements to integrate the disabled beginning in the 1960s as it does with the rise of asylums or the disputed discovery of “trisomie vingt-et-un.” Even the legacy of the condition’s name is a telling narrative about the modernization of medicine, from the use of the term ‘mongoloid’ to justify the (progressive for the time) anthropological theory of racial reversion to debates over whether to rename the disease in honor of John Langdon Down or place it within a more rigid taxonomy of congenital mental disorders. On their own, all of these stories are compelling windows into different dimensions of medicine, and as a whole they comprise a book that shows readers just how contested the process of ‘medicalizing’ a condition has always been. The book’s chapters progress both chronologically and thematically. We begin with the legal definition of idiocy in the English Common Law as a way for the state to regulate the inheritance of property, and a glance at different contemporary philosophical understandings of mental handicap. Then, Wright discusses John Langdon Down’s work at the Earlswood Asylum and the influence of both education reforms and genetic studies on the definition of mental handicap. Proceeding through Jérôme Lejeune’s disputed discovery of trisomy 21 and the role of genetic screening in abortion debates, the book concludes by discussing how social movements in the late twentieth century have profoundly affected the ethical and political dimensions of Down’s syndrome. Winner of the British Society for the History of Science’s 2013 Dingle Prize, awarded biennially to a book exemplifying critical focus and a novel perspective while remaining accessible to the public, Downs is a great read for specialists and non-specialists alike. Learn more about your ad choices. Visit megaphone.fm/adchoices

The acclaimed Canadian author Silver Donald Cameron writes that the idea for his newly reissued book, The Living Beach: Life, Death and Politics where the Land Meets the Sea (Red Deer Press, 2014), occurred to him when he was interviewing a “lean, laconic, geologist,” named Bob Taylor who works at the Bedford Institute of Oceanography in Halifax, Nova Scotia. “A beach stores sand in dunes behind it,” Taylor said. “When it’s attacked, it draws material from the dunes for itself and for building a protective shoal or bar offshore. When it’s less stressed, it takes sand and gravel from offshore and stores it back on the beach and in the dunes.” “You talk as though the damn thing were alive,” Cameron said. “I think of it that way,” said Taylor. At the time, Silver Donald Cameron thought of it as a vivid metaphor. But, in his newly revised version of The Living Beach, he argues that it’s true: the beach is alive with the right to be protected. His book explores all aspects of beaches including the plants and animals that live there, the sciences of biology, oceanography and geology that help us understand them, the politics of flood control, and beaches in stories, poetry and song. In 2009, The Living Beach was voted one of Atlantic Canada’s 100 best books. In 2014, Red Deer Press published a new revised edition. In this interview for the New Books Network, Silver Donald Cameron visits a beach at Parrsboro, Nova Scotia on the shores of the Minas Basin, home of the world’s highest tides. Learn more about your ad choices. Visit megaphone.fm/adchoices

Why do we study the history of science? Historians of science don’t just teach us about the past: along with philosophers of science, they also help us to understand the foundations and assumptions of scientific research, and guide us to reliable sources of information on which to base our policies and opinions. Jane Maienschein‘s new book is a model of the kind of careful, balanced, and beautifully written history of science that makes a significant contribution not just to the historiography of science, but also to the public understanding of science and its lived consequences. Embryos Under the Microscope: The Diverging Meanings of Life (Harvard University Press, 2014) traces the historical transformations in the observation and observability of the earliest stages of developing life. Maienschein’s account is a focused and thoughtfully organized book that gradually reveals aspects of the history of early stages of life, carefully curating the elements of her narrative such that they collectively inform broader debates over embryo-related policy in the contemporary United States. Readers follow animal and human embryos in their metamorphoses from hypothetical to observed entities, seeing them sequentially transform into experimental, computational, and engineered objects. The final chapter considers the implications of the story in light of recent debates on topics such as fetal pain, paying special attention to the distinction between making policy decisions based on metaphysics vs. science. Embryos Under the Microscope is equally well-suited to academic historians of science wanting a clear introduction to the history of developmental biology, general readers seeking an introduction to a crucial topic of social and political debate, and teachers interested in assigning one or more of the chapters in relevant undergraduate courses. Enjoy! You can find the related Embryo Project Encyclopedia, a wonderful digital and open access resource, here. Listeners might also be interested in this recent article on slate.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

The work of Charles Darwin, together with the writing of associated scholars of society and its organs and organisms, had a particularly global reach in the late nineteenth and early twentieth centuries. Marwa Elshakry‘s new book offers a fascinating window into the ways that this work was read and rendered in modern Arabic-language contexts. Reading Darwin in Arabic, 1860-1950 (University of Chicago Press, 2013) invites us into a late nineteenth-century moment when the notions of “science” and “civilization” mutually transformed one another, and offers a thoughtful and nuanced account of the ways that this played out for scholars working and writing in Syria and Egypt. The early chapters of Elshakry’s book focus on the central role played by popular science journals like Al-Muqtataf (The Digest) in translating and disseminating Darwin’s ideas. We meet Ya’qub Sarruf and Faris Nimr, young teachers at the Syrian Protestant College who were instrumental in translating scientific works into Arabic there and, later, in Egypt. An entire chapter looks closely at Isma’il Mazhar’s work producing the first verbatim translation of Darwin’s Origin of Species into Arabic, but the book also looks well beyond Darwin to consider broader Arabic discourses on the relationship between science and society, as those discourses were shaped by engagements with the work of Herbert Spencer, and many others. Elshakry pays special attention to the ways that this story is embedded in the histories of print culture, the politics of empire, and debates over educational reform, materialism, and socialism in the late nineteenth and early twentieth centuries, and concludes with a consideration of the continuing reverberations of these issues into late twentieth century Egypt and beyond. It is a must-read for anyone interested in the entanglements of science, translation, and empire in the modern world, and it will change the way we understand the place of Arabic interlocutors in the history of modern science. Learn more about your ad choices. Visit megaphone.fm/adchoices

Philosophy of science has come a very long way from its historically rooted focus on theories, explanations, and evidential relations in physics elaborated in terms of a rather mythical “theory T”. But even in philosophy of biology, attention has largely been on the concepts and abstract mathematics of evolutionary biology, not the in-the-trenches work of cell biology. Melinda B. Fagan, associate professor of philosophy at Rice University, stakes out new ground in Philosophy of Stem Cell Biology: Knowledge in Flesh and Blood (Palgrave Macmillan, 2013), which was recently selected as an outstanding academic title by Choice magazine. Fagan examines the interplay of experimental manipulation of cells and tissues with the mathematical modeling of cells and their developmental landscapes, and the interaction between the methods and goals of scientific knowledge production with the practical therapeutic goals of clinical medicine. She discusses the basic concepts of stem cell biology, its experimental and collaborative methods, and its models, and considers how these features alter our thinking about evidence, explanation, causality, unification, and the role of values in science. Learn more about your ad choices. Visit megaphone.fm/adchoices

For many years now, historians have wondered whether Hitler had any sort of consistent ideology. His writings are rambling and confusing. His speeches are full of plain lies. His “table talk” reflects a wandering, impulsive mind distinguished by a remarkable disconnection from reality. There are obvious themes: strident German nationalism, radical racialism, vicious anti-semitism, and militarism. Do these themes add up to an internally consistent “worldview”? Richard Weikart argues that they do. In his excellent book Hitler’s Ethic: The Nazi Pursuit of Evolutionary Progress (Palgrave MacMillan, 2011), Weickart points out that Hitler, like so many of his generation, was powerfully influenced by a particular reading of Darwin’s theory of evolution. By this interpretation, human “races” were seen as species and, as such, deemed to be in eternal struggle for life itself. “Nature,” according to these theorists (usually called “Social Darwinists”), selected the most fit races and destroyed the less fit. Weikart shows that Hitler held very fast to this idea, as can be seen both in his pronouncements and actions. He also shows that Hitler–in contrast to many other Social Darwinists–had no trouble leaping over the distinction between “is” and “ought.” According to the Fuhrer, the “fact” that the “races” were subject to evolutionary process meant that they should struggle with all their might. Here, might was ethically right by what Hitler believed was irrefutable “natural law.” It was a recipe for madness and, of course, immense tragedy. Listen in. Learn more about your ad choices. Visit megaphone.fm/adchoices

Sarah Franklin‘s new book is an exceptionally rich, focused yet wide-ranging, insightful account of in vitro fertilization (IVF) and the worlds that it creates and inhabits. Biological Relatives: IVF, Stem Cells, and the Future of Kinship (Duke University Press, 2013) treats IVF as a looking-glass in which can see not only ourselves, but also transformations in modern notions of biology, technology, and kinship. In addition to a fascinating ethnography of the various kinds of work (by artists, by scientists, by patients and doctors) at IVF and stem cell research facilities, readers will find insightful explorations of the work of Marx and Engels, Haraway, Plato, Strathern, Derrida, Firestone, along with a wide range of authors of feminist texts from the 1980s and after. It is a book full of hands, socks, pipettes, eggs, screens, organisms, and arguments, it is fascinating, and it was a great pleasure to talk with Sarah about it. Learn more about your ad choices. Visit megaphone.fm/adchoices

John Hibbing, Kevin Smith, and John Alford are the authors of Predisposed: Liberals, Conservatives, and the Biology of Political Differences (Routledge, 2013). Hibbing is professor of political science and psychology at the University of Nebraska, Smith is professor of political science at the University of Nebraska, and Alford is associate professor of political science at Rice University. Predisposed approaches the difference between liberals and conservatives from the perspective of physiology. Are we predisposed to certain beliefs or to one ideology or another? They answer emphatically “yes”. Those that call themselves liberals and conservative are biologically different in a host of ways that are deeply embedded in our biology. Learn more about your ad choices. Visit megaphone.fm/adchoices

When you open Eduardo Kohn‘s How Forests Think: Toward an Anthropology beyond the Human (University of California Press, 2013), you are entering a forest of dreams: the dreams of dogs and men, dreams about policemen and peccaries, dreams prophetic and dreams instrumental. In this brilliant new ethnography of a village in Ecuador’s Upper Amazon, those dreams are woven into the lives and deaths of a bookful of selves (both human and non-human) to help readers reconsider what it means to be a thinking, living being and why it matters to anthropology, science studies, and beyond. In creating this “anthropology beyond the human,” Kohn calls into question our tendency to conflate representation with language, rethinking the relationship between human language and other forms of representation that humans share with other beings. Here, human lives are both emergent from and contiguous with a wider semiotic community of were-jaguars and sphinxes, barking dogs and falling pigs, men and women alive and dead, walking stick insects and tanagers, spirit masters and rubber trees. It is a transformative, inspiring, and critically meticulous book that deserves a wide readership and rewards close reading. Learn more about your ad choices. Visit megaphone.fm/adchoices

Hallam Stevens‘s new book is a rich and fascinating ethnographic and historical account of the transformations wrought by integrating statistical and computational methods and materials into the biological sciences. Life Out Of Sequence: A Data-Driven History of Bioinformatics (University of Chicago Press, 2013) follows the data through the physical and virtual spaces from which the “new epistemic things” of bioinformatics have emerged. As computers were introduced into biology, they changed the nature of biological questions. Hallam traces the resulting reshaping of the practices, problems, and objects of biology, guiding readers through the pipeline to watch the transformation from material to digital as biological samples move through computational programs, get translated into ontologies, and become data. The histories of biology, computing, database technology, and bioinformatic imaging all play a role in this wonderfully trans-disciplinary story. Learn more about your ad choices. Visit megaphone.fm/adchoices

In his new collection of wonderfully engaging and provocative set of essays on Darwin and Darwinians, Robert J. Richards explores the history of biology and so much more. The eight essays collected in Was Hitler a Darwinian?: Disputed Questions in the History of Evolutionary Theory (University of Chicago Press, 2013), include reflections on Darwin’s theories of natural selection and divergence, Ernst Haeckel’s life and work, the evolutionary ideas of Herbert Spencer, the linguistic theories of August Schleicher, and the historical tendency to relate Hitler’s Nazism to Darwinian evolutionary theory. Individually, the essays are models of close and careful reading of the documentary traces of the life and work of Darwin, Haeckel, and others, and include some exceptionally affecting and tragic moments. Many of them touch on evolutionary theory’s moral character, its roots in Romanticism, and its conception of mankind. In addition to offering a fascinating set of case studies in the history of biology, the essays and appendices also collectively raise some important questions about how historians understand the past and bring it into narrative existence. What kind of thing is the past? What sets the history of science apart from other historical disciplines? Is it reasonable to use contemporary science to help construe the past? What is a scientific theory and where is it located? What does it mean to ask (and what might it look like to carefully answer) a question like, Was Hitler a Darwinian? The essays in Richards’ collection are wonderfully reflective considerations that reward the time and attention of both specialists in the history of biology and thoughtful general readers alike. Learn more about your ad choices. Visit megaphone.fm/adchoices

When it comes to understanding why our planet’s biodiversity is declining so precipitously, no phrase has as much explanatory power as “shifting baselines” — as essayist Derrick Jensen put it, “[T]he process of becoming accustomed to, and accepting as normal, worsening conditions.” Every generation regards its own environment as natural and healthy, failing to recognize that the status quo is but a pale imitation of what previous generations enjoyed. The term was coined by Daniel Pauly, a fisheries biologist, and it’s most often applied to the collapse of global fisheries. Our oceans are plundered, but our lack of historical context prevents us from noticing. John Waldman is determined to wake us up to what we’ve lost. Waldman, a professor of biology at Queens College, is the author of Running Silver: Restoring Atlantic Rivers and Their Great Fish Migrations (Lyons Press, 2013), a book that not only elucidates the predicament of plummeting fisheries, but also provides a roadmap for escaping it. Waldman’s focus is diadromous fish — the migratory species, like salmon, sturgeon, eels, and shad, that once ran in great pulses up and down every East Coast river, providing sustenance for ecosystems and human communities. Centuries of dam construction, overfishing, and other deleterious forces have reduced these once-spectacular migrations to just a fraction of their historic abundance; yet thanks to our shifting baselines, we seem scarcely to have noticed, which only makes the problem worse. Waldman calls this phenomenon — in which species disappear from people’s awareness and so lose their advocates — “eco-social anomie.” Fortunately, the news for migratory fish is not all catastrophic. Waldman documents a number of heartening restoration efforts, especially dam removals, that are helping some species rebound, and proving that diadromous fish still have constituents. While the Atlantic Coast’s fish runs may never return to their former glory, there’s still time to restore their relevance to ecosystems and human lives. “Poor shad!” wrote Henry David Thoreau, to whom Waldman’s book is dedicated. “Where is thy redress?” Running Silver certainly isn’t complete redress for our troubled rivers, but it offers a guide to making amends. Learn more about your ad choices. Visit megaphone.fm/adchoices

Men and women are different, there’s no doubt about it. And you might well want to know what the root of that difference is. What makes a man a man and a woman a woman? Before the beginning of the twentieth century, most answers to this question were rather unsatisfying, unless of course you like your answers religio-mythical or pseudo-scientific. Then scientists discovered a genetic difference that seemed to correspond to sexual dimorphism: the 23rd pair of chromosomes was XX in (almost all) human females and XY in (almost all) human males. Thus was a research program born, one prefect for the age of molecular genetics: the search for “sex itself.” In her fascinating book Sex Itself: The Search for Male and Female in the Human Genome (University of Chicago Press, 2013), Sarah S. Richardson explores the ways in which molecular geneticists pursued this program and, just as importantly, the ways in which their “findings” were molded by contemporary attitudes toward sex and gender. The science we see in Sex Itself is not just about “the facts”; it’s about facts embedded in culture. She shows how the two–sexual science and culture–did a sort of dance, each leading the other about the floor of public discourse. Sometimes the dance is beautiful; other times the dancers stumble all over each other. Listen in to our lively discussion. Learn more about your ad choices. Visit megaphone.fm/adchoices

Is genetic testing a new national obsession? From reality TV shows to the wild proliferation of home testing kits, there’s ample evidence it might just be. And among the most popular tests of all is for so-called “Native American DNA.” All of this rests upon some uninterrogated (and potentially destructive) assumptions about race and human “origins,” however. In Native American DNA: Tribal Belonging and the False Promise of Genetic Science (University of Minnesota Press, 2013), Kim TallBear asks what’s at stake for Indigenous communities and First Nations when the premises of this ascendant science are put into practice. TallBear, an Associate Professor of Anthropology at the University of Texas-Austin and enrolled Sisseton-Wahpeton Oyate, conducted years of research on the politics of “human genome diversity,” decoding the rhetoric of scientists, for-profit companies, and public consumers. The result is a vital and provocative work, tracing lineages between racial science and genetic testing, “blood talk” and “DNA talk,” and the undemocratic culture of a field which claims it can deliver us from racism. Learn more about your ad choices. Visit megaphone.fm/adchoices

Between WWII and the 1970s, prominent researchers from various fields established and defended a view that emotions are integral to the self, and that a mother’s love determines an individual’s emotional development. In Marga Vicedo, The Nature and Nurture of Love: From Imprinting to Attachment in Cold War America (University of Chicago Press, 2013), Marga Vicedo explores the emergence of the science of children’s emotional needs in the twentieth century. Masterfully bringing together approaches from the history and philosophy of the biological sciences, Vicedo’s book focuses on British psychoanalyst and psychiatrist John Bowlby (1907-1990), whose ethological work became one of the most influential and controversial psychological theories of the 20th century. Vicedo uses the story of Bowlby’s science to explore a broader modern history of work on animal and human behavior that includes Konrad Lorenz, Anna Freud, Benjamin Spock, and Niko Tinbergen, among others. Along the way, The Nature & Nurture of Love chronicles the emergence of a kind of anthropomorphic material culture of the human sciences, inhabiting its story with a fascinating cast of robots, dolls, geese, monkeys, and stuffed animals, as well as humans. It is a fascinating and gripping trans-disciplinary story and an absolute pleasure to read. Learn more about your ad choices. Visit megaphone.fm/adchoices

If you think about it, pretty much everything has a history insofar as everything exists in time. Historians, however, usually limit themselves to the history of humans and the things humans make. Occasionally, of course, they make forays into the history of animals, the environment and even the universe (see “Big History”), but these excursions are exceptions to the all-human rule. In Virus Hunt: The Search for the Origin of HIV (Oxford UP, 2013), Dorothy H. Crawford–a biologist–breaks new historiographical ground by tracing the history of a virus, namely HIV. She is, naturally, interested in the tragic human story of HIV and AIDS. But her focus is on the virus itself. Where and when, she asks, was HIV born? In what populations did it live before it jumped to humans? And, most importantly, where and when did it jump to humans? Using an array of sophisticated tools, a group of biologists-cum-detectives were able to give credible answers to these historical questions. Crawford tells their story. Learn more about your ad choices. Visit megaphone.fm/adchoices

During the 1924-25 school year, John Scopes was filling in for the regular biology teacher at Rhea County Central High School in Dayton, Tennessee. The final exam was coming up, and he assigned reading from George W. Hunter’s 1914 textbook A Civic Biology to prepare students for the test. What followed has become one of the most well-known accounts in the history of science and one of the most famous trials of twentieth-century America. In Trying Biology: The Scopes Trial, Textbooks, and the Anti-Evolution Movement in American Schools (University of Chicago Press, 2013), Adam R. Shapiro urges us to look beyond the rubrics of “science” and “religion” to understand how the Scopes trial became such an important event in the histories of both. The story begins with a pair of Pinkerton detectives spying on a pair of textbook salesmen in the Edwards Hotel in Jackson, Mississippi. Shapiro brings us from that hotel room into a series of classrooms, boardrooms, and courtrooms while exploring the battle over textbook reform in the twentieth-century US. Based on a close reading of high school curricular materials around the discipline of botany, with special attention to the emergence of “civic botany” as a pedagogical field, Shapiro’s book uses the debates over pedagogy, evolution, and the textbook industry to explore a number of issues that are of central importance to the history of science: the construction of authorship, the histories of reading practices, the co-emergence of economies and technologies, and the ways that urban and rural localities shape the nature of sciences and their publics. It is a gripping, moving, and enlightening story. Enjoy! Learn more about your ad choices. Visit megaphone.fm/adchoices

On the day you were born, you arrived with your own unique biology and into your own unique social and cultural context. It would have been impossible to predict on that day how your life would unfold, or exactly the person you would become in the future. Why? Because there are so many complex and interrelated factors in the development of each and every human being. In his new book, The Human Spark: The Science of Human Development (Basic Books, 2013) world-renowned psychology professor Jerome Kagan tackles some of the most fascinating and important questions about what makes a human a human, and how we become who we are over the course of our lives. He draws from his decades of experience in developmental psychology, as well biology, neuroscience, and even literature and biographies, to inform his nuanced and big-picture view. And never one to shy away from critical thinking, Kagan also provides thoughtful remarks on the limitations of psychology as a field of research. If you want to listen to a person with an amazing mind and decades of experience talk about psychology, this is the interview for you! Learn more about your ad choices. Visit megaphone.fm/adchoices

Humans are quite a bit like chimpanzees, genetically speaking. Of course humans are quite a bit like fruit flies, genetically speaking. But when it comes to behavior, humans are much more like chimpanzees than fruit flies. And so the question arrises: what can we learn about ourselves from chimpanzees? According to the veteran ethologist Frans De Waal, the answer is this: we are not the only species that lives in a moral universe. De Waal should know, because he’s been studying humans and chimpanzees for decades. In his new book The Bonobo and the Atheist: In Search of Humanism Among Primates (Norton, 2013), De Waal points out that chimpanzees (and bonobos) show nearly the full range of “human” attachments, affects, and emotions. They love, feel loss, sulk, get angry, have fights, and make up. Just as important, they abide by conventional rules that give their groups order and assist cooperation. To De Waal, there is no doubt that all of these primate behavioral traits were evolved. Just so, he says, were they evolved in humans. In the interview we discuss the implications of this viewpoint for human life, and religious faith in particular. Learn more about your ad choices. Visit megaphone.fm/adchoices

“This is a history of promises.”So begins Nathaniel Comfort‘s gripping and beautifully written new book on the relationships between and entanglements of medical genetic and eugenics in the history of the twentieth century. Based on a rich documentary and oral history archive, The Science of Human Perfection: How Genes Became the Heart of American Medicine (Yale University Press, 2012) reframes the histories of early and contemporary human genetics. Rather than treating eugenics as “a contaminant of good, honest biomedicine,” the book shows that early human genetics had many of the same basic goals – human improvement and the relief of suffering – as genetic medicine today. At the same time, contemporary genetic medicine emerges as much less benign than it has often been depicted. All of this is accomplished through a sensitive historical tracing of two major approaches to understanding human heredity through the twentieth century: a Galtonian approach characterized by a concern with quantification, public health, and populations; and a Garrodian approach characterized by an interest in conceptualizing the human as individual, and in synthesizing heredity with other forms of knowledge. As we follow these threads along with Comfort, he introduces us to a bookful of colorful, vibrant characters from the history of medical genetics: the idealistic inventor of a “Gumption Reviver,” the sanitarium-operator who was fond of prescribing yogurt-enemas, and the medical geneticist with a talent for boogie-woogie piano, among others. These figures are embedded in an exceptionally carefully-wrought narrative of the spaces, practices, and events by which medicine became genetic, genetics became molecular, and molecules made the engineering of humanity possible in a new way. In the course of our discussion, we talked about the importance, for Comfort, of paying careful attention to elements of the writer’s craft when composing a historical work. The John McPhee essay on narrative structure that was mentioned in that part of the interview can be found here (A subscription to the New Yorker is required to read the full piece.) The Oral History of Human Genetics Project can be found here. Learn more about your ad choices. Visit megaphone.fm/adchoices

There are pigeons, cats, and Martians here. There are CT scanners, dentures, computers large enough to fill rooms, war games, and neural networks. In Biomedical Computing: Digitizing Life in the United States (Johns Hopkins University Press, 2012), Joe November mobilizes this ecology of instruments and objects, people and programs, in a story that maps out the early years of the introduction of computers to biology and medicine from 1955 to 1965. As computing technology was gradually integrated into different spaces of biomedicine that were characterized by agents with very different agendas (a set of processes not without significant contestation), biomedicine and computing transformed one another. Life itself was changed as a result, as the objects of biomedical computing were translated into the kinds of system-entities that computers could describe. The historian of technology who reads November’s book will find fascinating stories of machines like LINC, ENIAC, and UNIVAC. The historian of science will find accounts of the ways that military funding shaped the computerization of biomedicine, windows into the mid-century work supported by the NIH, stories of the transformation of diagnostic medicine in the US, and chapters from the history of crystallography and molecular biology. The historian of networks and computing will find analyses of the importance of operations research, expert systems, and transdisciplinary research practices to the work of some of the central figures in the history of the computational sciences. In addition to all of this, November’s book can also be read as a history of the modern personal computer. (There are also men in RNA-themed neckties sprinkled throughout the early part of the story.) Enjoy the interview, and imagine as you listen that you’re here with me at the National Humanities Center, Skyping with Joe as a thunderstorm booms overhead, rain falls loudly outside the window, and brilliant humanities scholars share excited conversation about their work outside the door. It was a special afternoon. Learn more about your ad choices. Visit megaphone.fm/adchoices

The Hebrews called it “Eden.” The Greeks and Romans called it the “Golden Age.” The philosophes–or Rousseau at least–called it the “State of Nature.” Marx and Engels called it “Primitive Communism.” The underlying notion, however, is the same: there was a time, long ago, when things were much better than they are today because we were then “in tune” with God, nature, or whatever. Thereafter we “fell,” usually due to our own stupidity, and landed in our present corrupted state. Today we are told by some that the paleolithic period (roughly 3 million to 10,000 years ago) was, similarly, a time in which we were “in tune” with nature. According to the paleofantasists, we were selected in the paleolithic environment and it is to the Paleolithic environment that we became most “fit.” After the paleolithic, they say, came the fall (domestication, cities, states, industrialization). Today, they continue, we are “out of tune” and, as a result, we are suffering all kinds of nasty consequences. Or so the story goes. But Marlene Zuk says it just ain’t so. In Paleofantasy: What Evolution Really Tells Us about Sex, Diet, and How We Live (W. W. Norton, 2013), she points out that we were always out of tune because evolution makes it impossible to be truly “in tune.” The environment was always changing and we were always changing;the environment is still changing and we are still changing. What is “natural” to us is a kind of moving target. One millenium something seems “natural”; the next millenium not so much. Evolution is a ceaseless and surprisingly rapid process. Learn more about your ad choices. Visit megaphone.fm/adchoices

Genentech: The Beginnings of Biotech (University of Chicago Press, 2011) tells many stories of many things. It is the story of a handful of people who figured out how to make recombinant DNA technology into a thriving business. It is the story of the emergence of a new hybrid organism, the entrepreneurial biologist, who lived with one leg in academia and one in corporate research. It is the story of a series of compounds that became big business in the American corporate world: human insulin, human growth hormone, and interferon among them. Drawing on a series of fascinating oral histories, Sally Smith Hughes recounts all of these tales as they unfolded in a volatile environment sparking with questions over the political and ethical implications of recombinant DNA technology: Could living organisms be patented? Did scientists own their research materials? When a team of scientists discovered something that was worth millions or billions of dollars, who should get credit and reap the rewards? Hughes’ story manages to address these major issues without sacrificing the human stories and colorful characters behind the rise of Genentech. For the Bancroft Library Program in Bioscience and Biotechnology Studies Regional Oral History Office, see this website. Learn more about your ad choices. Visit megaphone.fm/adchoices

In Rereading the Fossil Record: The Growth of Paleobiology as an Evolutionary Discipline (University of Chicago Press, 1012), David Sepkoski tells a story that explains the many ways that paleontologists have interpreted the meaning and importance of fossils in the light of evolutionary theory. Starting with Darwin and his dilemma concerning the fossil record, Sepkoski tracks the relationships between paleontology and evolutionary theory over the course of the twentieth century. As it was formulated at mid-century the evolutionary synthesis did not really allow paleontology to contribute to evolutionary theory and it fell to a self-consciously revolutionary generation of paleontologists in the 1970s to argue that reading the fossil record could change the theory of evolution. Drawing on increasingly sophisticated ways of modeling and simulating evolutionary processes, as well as on increasingly available computational power, paleobiologists built institutions and articulated ideas, such as punctuated equilibrium, mass extinction, and macroevolution, that demonstrated how the history of life revealed by reading the fossil record can amend evolutionary theory. Learn more about your ad choices. Visit megaphone.fm/adchoices

Did Proust have it right? Does food, whether it’s a madeleine from an aristocratic childhood or the Velveeta mac-and-cheese my mom used to make, have a special significance for our memory, perhaps even our very being? In his new book, The Omnivorous Mind: Our Evolving Relationship to Food (Harvard University Press, 2012), neuroanthropologist John. S. Allen takes up this question by guiding us into the inner structures of the brain, into the hippocampus and amygdala, where memories and emotions mix and where food plays a surprising role. But Allen’s book doesn’t just journey into the brain. It travels back in time, to the origins of modern humanity, showing us how our evolutionary past shapes our eating present. Along the way, we learn about the eating habits of Neanderthals and chimpanzees; we discover the benefits of being omnivores and even superomnivores; and we investigate why a food quality as seemingly straightforward as crispiness makes our mouths water. Here’s a hint: the exoskeletons of insects might have something to do with our love of Colonel Sanders’ extra crispy recipe. Please join us for a discussion of how and why we eat that begins millions of years ago and ends every time we sit down at the table with our 1,400 cc of human brain. Learn more about your ad choices. Visit megaphone.fm/adchoices

The ability to figure out the mental lives of others – what they want, what they believe, what they know — is basic to our relationships. Sherlock Holmes exemplified this ability by accurately simulating the thought processes of suspects in order to solve mysterious crimes. But folk psychology is not restricted to genius detectives. We all use it: to predict what a friend will feel when we cancel a date, to explain why a child in a playground is crying, to deceive someone else by saying less than the whole story. Its very ubiquity explains why it is called folk psychology. But how in fact does folk psychology work? On standard views in philosophy and psychology, folk psychology just is the practice of ascribing or attributing beliefs and desires to people for explaining and predicting their behavior. A folk psychologist is someone who has this “theory of mind”. In her new book, Do Apes Read Minds?: Toward a New Folk Psychology (MIT Press, 2012), Kristin Andrews, associate professor of philosophy at York University in Toronto, argues that the standard view is far too narrow a construal of what’s going on. It leaves out a wide variety of other mechanisms we use to understand the mental lives of others, and a wide variety of other reasons we have for engaging in this social competence. Moreover, what’s necessary to be a folk psychologist is not a sophisticated metacognitive ability for ascribing beliefs, but an ability to sort the world into agents and non-agents – an ability that greatly expands the class of creatures that can be folk psychologists. Andrews draws on empirical work in psychology and ethology, including her own field work observing wild primates, to critique the standard view and ground her alternative pluralistic view. Learn more about your ad choices. Visit megaphone.fm/adchoices

Simply put: you should read Andrew F. Jones‘s new book, Developmental Fairytales: Evolutionary Thinking and Modern Chinese Culture (Harvard UP, 2011). It is both an immense pleasure to read, and a truly brilliant study of the ways that a discourse of development was taken up from evolutionary works of Lamarck,... Learn more about your ad choices. Visit megaphone.fm/adchoices

One of the most disturbing insights made by practitioners of “Big History” is that the distinction between geologic time and human time has collapsed in our era. The forces that drove geologic time–plate tectonics, the orientation of the Earth’s axis relative to the sun, volcanic activity–were distinct from the forces that drove human time–evolution, technological change, population growth. To be sure, they interacted. But the causal arrow always went from geologic change to human change. As Anthony Penna rightly points out in The Human Footprint: A Global Environmental History (Wiley-Blackwell, 2010), the causal arrow now goes in both directions. Not only do we adapt to the environment, but the environment is adapting to us, and mightily. We are ushering in a new geological period sometimes called the Anthropocene–the era defined by human activity. It’s important to point out that this is not the first time biology has shaped geology: we have good evidence, for example, that 2.4 billion years ago cyanobacteria radically altered the Earth’s atmosphere by releasing enormous quantities of free oxygen (“The Great Oxygenization Event“). This time, however, it’s different. Cyanobacteria are essentially dumb machines. They could not choose whether they would oxygenate the atmosphere or not. In contrast, we are smart machines. We can choose how we want to alter the environment. Penna tells the story of how we have been altering the environment–and choosing to alter the environment–for the past 50,000 years, and with particular vigor in the past several hundred. We are now masters not only of our own fate, but the fate of the Earth and all life on it. We need to wake up to that fact, and we should thank Anthony Penna for helping to stir us from our slumbers. Learn more about your ad choices. Visit megaphone.fm/adchoices

What should we study? The eighteenth-century luminary and poet Alexander Pope had this to say on the subject: “Know then thyself, presume not God to scan; The proper study of mankind is man ” (An Essay on Man, 1733). He was not alone in this opinion. The philosophers of the Enlightenment–of which we may count Pope–all believed that humans would benefit most from a proper comprehension of temporal things, and most particularly humanity itself. For them, understanding humanity meant, first and foremost, understanding the human body. Naturally, then, the philosophes and their successors paid close attention to the body. They cut it up, took it apart, measured it and attempted to see how it worked. They were most interested in one part in particular–the human head. It was the seat of the human characteristic the Enlightenment scientists admired most: intelligence. If one could get a handle on the human cranium, then one would understand what it meant to be human. Or at least so they thought. In her fascinating new book The Skull Collectors: Race, Science and America’s Unburied Dead (University of Chicago Press, 2010), Ann Fabian introduces us to a group of American philosophes who began to collect and study human crania in the first half of the nineteenth century. Not surprisingly, they took most of their cues from their European counterparts. They did, however, adapt craniology to a peculiar American context. Living in a social order in part built on supposed racial difference, the American skull collectors knew that what they said about Africans mattered. Their work could support the suppositions of slavery, or not. Moreover, living in a social order that was at the very time they were working involved in a quasi-genocidal campaign against indigenous peoples, the American skull collectors knew that what they said about Native Americans mattered as well. Their work might buttress the movement for Indian removal, or it might not. And being people of the “New World,” the American skull collectors knew that they were looked down upon by many of their European colleagues. They needed to collect skulls aggressively in order to establish craniology as an American science. As one might expect, the American skull collectors were, by our lights, a strange bunch. Racists, imperialists, and nationalists to be sure. But also scientists, curators, and founders of physical anthropology. Thanks to Ann for bringing them to us in all their contradictory richness. Please become a fan of “New Books in History” on Facebook if you haven’t already. Learn more about your ad choices. Visit megaphone.fm/adchoices

Long ago, historians more or less gave up on “theories of history.” They determined that human nature was too unpredictable, cultures too various, and developmental patterns too evanescent for any really scientific theory of history to be possible. Human history, they said, was chaos. The problem is that human history isn’t chaos at all. The “hard” human sciences–evolutionary biology and anthropology in particular–have shown that human nature is quite predictable, cultural variability is strictly constrained, and ongoing patterns of social development have ancient roots. Historians can ignore these facts all they like, but that doesn’t make them any the less true. It does, however, impoverish their discipline by ceding the search for a satisfying theory of history to scientists. Neither Paul Bingham nor Joanne Souza are historians. The former is a molecular biologist and the latter an evolutionary psychologist. But they have formulated an elegant theory of human history in Death From a Distance and the Birth of a Humane Universe (2009). Like any good theory, it explains a lot with a little. To put it briefly, human society has gone from simple/small to massive/complex because humans alone among animals were/are able to suppress intra-group conflicts of interest by means of low-cost coercion. Bingham and Souza point out that the big “jumps” in social size and complexity–the neolithic revolution, the growth of archaic states, the birth of the nation-state, the rise of globalization–have all been associated with the evolution/introduction of new, more powerful coercive abilities. Paradoxically, it was new weapons that created more and better lives over the course of the last several hundred thousand years. This brief summary cannot do justice to the richness of Bingham’s and Souza’s theory. You need to read it for yourself. When you do, I guarantee you will see the past and present in a new way. Please become a fan of “New Books in History” on Facebook if you haven’t already. Learn more about your ad choices. Visit megaphone.fm/adchoices

First, the conventional wisdom. Because Homo sapiens are a young species and haven’t had time to genetically differentiate, we modern humans are all basically genetically identical. Because Homo sapiens figured out ways to use culture to overcome natural selection, human genetic evolution ceased ages ago. Because Homo sapiens are genetically very similar and not subject to natural selection, the differences that we see today among modern human groups are the result of cultural processes, not genes. Not so say Gregory Cochran and Henry Harpending in their challenging and sure-to-be-controversial new book The 10,000 Year Explosion: How Civilization Accelerated Human Evolution (Basic Books, 2009). We are extraordinarily similar genetically, but the minor differences occasionally had very important consequences: a difference of one or two nucleotides–among billions–could mean life or death for entire populations.These minor differences, where advantageous, were selected for and spread in the ordinary natural selective way: if you developed resistance to malaria in the tropics, you survived and your genes were passed on; if not, then not. Finally, these genetic advantages accumulated: populations that had been put under more “pressure” were more robust than those living in relaxed environments.The more robust populations prospered; the less robust did not. Interesting for the historian will be the point that most of the enhanced “pressure” was due to historical factors. According to Cochran and Harpending, the transition to agriculture roughly 10,000 years ago in particular forced Homo sapiens to do things that they were not “programmed” (so to say) to do. Those who adapted genetically survived; those who did not, did not. Thus Homo sapiens 1.0 (the hunter-gatherer model) evolved into Homo sapiens 2.0 (the farming model). Cochran and Harpending submit that this process–natural selection due to cultural pressure–has been going on quite recently and may be going on today. For example, they propose that historical factors in the European Middle Ages favored the differential reproduction of brainy Ashkenazi Jews, the results of which can be seen in the differential success of their descendants in brainy occupations. Hackle-raising stuff to be sure. Is any of it true? Listen to the interview, read the book and decide for yourself. Please become a fan of “New Books in History” on Facebook if you haven’t already. Learn more about your ad choices. Visit megaphone.fm/adchoices