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Neuro-Oncology: The Podcast

Neuro-Oncology: The Podcast

137 episodes — Page 3 of 3

PI3K signaling in IDH mutant gliomas

Dr. Evan Noch interviews Dr. Joanna Phillips about her and her team manuscript entitled: "PI3K/AKT/mTOR signaling pathway activity in IDH-mutant diffuse glioma and clinical implications", published online in Neuro-Oncology in March 2022.

May 6, 202224 min

Cell-free DNA from CSF in pediatric, adolescent and young adult patients

Dr. Iyad Alnahhas interviews Dr. Matthias Karajannis about his and his team's recent manuscript entitled: "Next-generation sequencing of cerebrospinal fluid for clinical molecular diagnostics in pediatric, adolescent and young adult (AYA) brain tumor patients", published in Neuro-Oncology in February 2022

Apr 22, 202210 min

Molecular determinants of neurocognitive deficits in glioma

Dr. Ankush Bhatia interviews Dr. Emma van Kessel about her and her team's recent manuscript entitled "Tumor-related molecular determinants of neurocognitive deficits in patients with diffuse glioma", published online in Neuro-Oncology in February 2022. Full Report

Apr 8, 202218 min

H3K27M cell-free tumor DNA tracking in response to ONC201 treatment for diffuse midline glioma

Dr. Iyad Alnahhas interviews Dr. Carl Koschmann about his and his team's recent manuscript entitled: "Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline glioma" published online in Neuro-Oncology in February 2022. Read the Study

Mar 25, 202222 min

Clinical trial accrual for women and minorities in neuro-oncology

Dr. Rachna Malani interviews Dr. Hervey-Jumper about his and his team's recent manuscript entitled "A population study of clinical trial accrual for women and minorities in neuro-oncology following the NIH revitalization act", published online in Neuro-Oncology in January 2022. See study here

Mar 11, 202228 min

The clinical utility of next generation sequencing for IDHwt glioblastoma

Dr. Evan Noch interviews Dr. Mary Jane Lim-Fat about her and her team's recent manuscript entitled: "Clinical utility of targeted next generation sequencing assay in IDH-wildtype glioblastoma for therapy decision-making", published online in Neuro-Oncology in December 2021.

Feb 11, 202222 min

Trabectedin for recurrent grade 2 or 3 meningiomas

Dr. Iyad Alnahhas interviews Dr. Matthias Preusser about the recent manuscript entitled: "Trabectedin for recurrent WHO grade 2 or 3 meningioma: a randomized phase 2 study of the EORTC Brain Tumor Group (EORTC-1320-BTG)", published online in Neuro-Oncology in October 2021.

Jan 28, 202217 min

Glioblastoma cell heterogeneity and plasticity

Dr. Iyad Alnahhas interviews Drs. Simone Niclou and Anna Golebiewska about their recent manuscript, entitled: 'Cancer Cell Heterogeneity and Plasticity: A Paradigm Shift in Glioblastoma', published online in Neuro-Oncology in December 2021.

Jan 14, 202213 min

Moleculary integrated grading for meningioma

Dr. Nicholas Butowski interviews Drs. Sandro Santagata and Wenya Linda Bi about their recent manuscript entitled: "A molecularly integrated grade for meningioma", published online in Neuro-Oncology in September 2021.

Dec 24, 202128 min

BOLD fMRI in IDH mutant gliomas

Dr. Ankush Bhatia interviews Dr. Jack Grinband about his recent manuscript entitled "BOLD Asynchrony Elucidates Tumor Burden in IDH-Mutated Gliomas", published online in Neuro-Oncology in July 2021

Dec 10, 202128 min

Glioblastoma subtypes and response to Dasatinib

Dr. Evan Noch interviews Drs. Emma Phillips and Violaine Goidts about their recent manuscript entitled "A Novel Patient Stratification Strategy to Enhance the Therapeutic Efficacy of Dasatinib in Glioblastoma", published online in Neuro-Oncology in July 2021.

Nov 26, 202122 min

Resection for recurrent brain metastases

Dr. Iyad Alnahhas interviews Dr. Alexander Hulsbergen about his and his team's recent manuscript entitled: "Neurosurgical resection for locally recurrent brain metastases", published online in Neuro-Oncology in July 2021.

Nov 12, 202116 min

Incidental Meningiomas

Dr. Jasmin Jo interviews Dr. Jason Sheehan about the recent manuscript entitled: "A Multicenter Matched Cohort Analysis of Incidental Meningioma Progression During Active Surveillance or After Active Stereotactic Radiosurgery: The IMPASSE Study", published online in Neuro-Oncology in June 2021.

Oct 29, 202119 min

Immunosuppression in IDH mutant gliomas

Dr. Maya Graham interviews Dr. Nduka Amankulor about the recent manuscript entitled: "Characterization of systemic immunosuppression by IDH mutant glioma small extracellular vesicles" published online in Neuro-Oncology in July 2021.

Oct 15, 202129 min

Immunotherapy for melanoma brain metastases

Dr. Ankush Bhatia interviews Dr. Hussein Tawbi about his and his team's recent manuscript entitled "Safety and efficacy of the combination of nivolumab plus ipilimumab in patients with melanoma and asymptomatic or symptomatic brain metastases: Checkmate-204", published online in Neuro-Oncology in April 2021.

Oct 1, 202132 min

DNA methylation profiles within the CATNON trial

Dr. Iyad Alnahhas interviews Dr. Pim French about his and his team recent manuscript entitled: "Prognostic significance of genome-wide DNA methylation profiles within the randomised, phase 3, EORTC CATNON trial on non-1p19q deleted anaplastic glioma", published online in Neuro-Oncology in April 2021

Sep 17, 202117 min

18F FET PET in childhood CNS tumors

Description: Dr. Maya Graham interviews Dr. Lisbeth Marner about her recent manuscript "" Diagnostic accuracy and clinical impact of 18F FET PET in childhood CNS tumors" " published online in April 2021 in Neuro-Oncology.

Sep 3, 202117 min

Checkpoint blockade in atypical meningiomas

Description: Dr. Nicholas Butowski interviews Dr. David Reardon about his recent manuscript "Activity of PD-1 blockade with nivolumab among patients with recurrent atypical/anaplastic meningioma: phase II trial results", published online in Neuro-Oncology in May 2021.

Aug 20, 202139 min

Molecular signatures of glioma causation

Dr. Evan Noch interviews Dr. Elizabeth Claus about her recent manuscript entitled: "Environmental and sex-specific molecular signatures of glioma causation" published online in Neuro-Oncology in May 2021.

Aug 6, 202122 min

Testing methods for MGMT promoter methylation

Dr. Iyad Alnahhas interviews Dr. Kathreena Kurian about her and her team's recent manuscript entitled: "MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a Cochrane Review", published online in Neuro-Oncology in April 2021.

Jul 23, 202113 min

Temozolomide-induced hypermutation in IDH-mutant low-grade gliomas

Dr. Maya Graham interviews Dr. Nancy Ann Oberheim Bush about her and her team's paper entitled " Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas" published online in Neuro-Oncology in April 2021

Jul 9, 202113 min

Posterior fossa syndrome

Dr. Iyad Alnahhas interviews Dr. Raja Khan about their recent manuscript entitled "Clinical features, neurologic recovery, and risk factors of post-operative posterior fossa syndrome and delayed recovery: a prospective study", published online in April 2021 in Neuro-Oncology.

Jun 18, 202121 min

Loss of H3K27me3 in meningiomas

Dr. Evan Noch interviews Drs. Farshad Nassiri and Justin Wang from the team of Dr. Gelareh Zadeh about their recently published paper entitled "Loss of H3K27me3 in meningiomas" published online in Neuro-Oncology in May 2021.

Jun 4, 202126 min

Loss of H3K27me3 in the Tübingen meningioma cohort

Dr. Maya Graham interviews Drs. Ghazaleh Tabatabai and Felix Behling about their paper entitled "H3K27me3 loss indicates an increased risk of recurrence in the Tübingen meningioma cohort" published online in Neuro-Oncology in December 2020.

May 21, 202118 min

A prospective phase II randomized trial of proton radiotherapy vs intensity modulated radiotherapy for patients with newly diagnosed GBM

Dr. Jasmin Jo interviews Dr. Caroline Chung about her paper: "A prospective phase II randomized trial of proton radiotherapy vs intensity modulated radiotherapy for patients with newly diagnosed GBM" published online in Neuro-Oncology in Feb 2021.

May 7, 202113 min

Brain radiotherapy and decline in fine motor skills

Dr. Iyad Alnahhas interviews Dr. Jona Hattangadi-Gluth and Ms. Mia Salans about their recently published manuscript entitled: "Longitudinal change in fine motor skills after brain radiotherapy and in vivo imaging biomarkers associated with decline" published online in February 2021 in Neuro-Oncology.

Apr 9, 202118 min

A serum based DNA methylation assay to detect gliomas

Dr. Iyad Alnahhas interviews Dr. Houton Noushmehr about his recent paper "A serum-based DNA methylation assay provides accurate detection of glioma", published online in Feb 2021 in Neuro-Oncology

Mar 26, 202133 min

Ep 9PTEN deficiency and proteosome addiction in glioblastoma

Dr. Evan Noch interviews Drs. Frank Furnari and Jorge Benitez about their recent paper: "PTEN deficiency leads to proteosome addiction, a novel vulnerability in glioblastoma" published online in Neuro-Oncology in January, 2021.

Mar 12, 202123 min

Ep 8Cold-Inducible RNA-Binding Protein expression and recurrence of brain metastases

Dr. Alireza Mansouri interviews Dr. Matthew Dankner about his recent paper "Invasive growth associated with Cold-Inducible RNA-Binding Protein expression drives recurrence of surgically resected brain metastases" published online in Neuro-Oncology in January, 2021.

Feb 26, 202111 min

Ep 7The incidence of brain metastases among patients with metastatic breast cancer

Dr. Iyad Alnahhas interviews Dr. Katarzyna Jerzak about her recent paper "The incidence of brain metastases among patients with metastatic breast cancer: a systematic review and meta-analysis", published online in Neuro-Oncology in December, 2020.

Feb 12, 202123 min

Ep 6Epidemiology of Brainstem High-Grade Gliomas in Children and Adolescents in the United States, 2000-2017

Dr. Evan Noch interviews Dr. Jill Barnholtz-Sloan about her recent paper "Epidemiology of Brainstem High-Grade Gliomas in Children and Adolescents in the United States, 2000-2017" published online in Neuro-Oncology in December 2020.

Jan 29, 202117 min

Ep 5A large longitudinal study of patients with Neurofibromatosis Type 2.

Dr. Iyad Alnahhas interviews Dr. Gareth Evans about his recent paper in Neuro-Oncology entitled: "Disease course of Neurofibromatosis Type 2; a 30-year follow-up study of 353 patients seen at a single institution

Jan 15, 202120 min

Ep 4Vorinostat and bevacizumab for recurrent glioblastoma

Dr. Iyad Alnahhas interviews Drs. Vinay Puduvalli and Ying Yuan about their paper "A Bayesian adaptive randomized phase II multicenter trial of bevacizumab with or without vorinostat in adults with recurrent glioblastoma" published in Neuro-Oncology in March 2020

Jan 1, 202132 min

Ep 3A subset of pediatric thalamic gliomas

Dr. Iyad Alnahhas talks with Dr. Felix Sahm about his recently published article in Neuro-Oncology entitled: "A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR," published online on November 1, 2020.

Dec 18, 202020 min

Ep 2Supratotal resection of lower-grade gliomas

Dr. Alireza Mansouri talks with Dr. Lorenzo Bello about his recently published article in Neuro-Oncology entitled: "Association of Supratotal Resection with Progression-Free Survival, Malignant Transformation, and Overall Survival in Lower-Grade Gliomas," published online on October 13, 2020.

Dec 4, 202019 min

Ep 1Friends of SNO

In this premiere episode, we will bring you some brief conversations with the current leaders of: The Society for Neuro-Oncology, the European Association of Neuro-Oncology, The Asian Society for Neuro-Oncology and the World Federation of Neuro-Oncology Societies

Nov 20, 202025 min

Announcing Neuro-Oncology: The Podcast

trailer

Dr. Iyad Alnahhas, producer, introduces the new podcast.

Nov 19, 20200 min