Neuro-Oncology: The Podcast

Dr. Iyad Alnahhas interviews Drs. Minyoung Oh and Hyungwoo Cho about their recent manuscript entitled: "Enhancing Prognostication and Treatment Response Evaluation in Primary CNS Lymphoma with 18F-FDG PET/CT", published online in Neuro-Oncology in August 2024. Link to manuscript

Dr. Jasmin Jo interviews Dr. Monika Hegi about her and her team's recent manuscript entitled: "No benefit from TMZ treatment in GB with truly unmethylated MGMT promoter: Reanalysis of the CE.6 and the pooled Nordic/NOA-08 trials in elderly GB patients", published online in Neuro-Oncology in (I will fill in through Libsyn)

Dr. Maya Graham interviews Dr. Martin van den Bent about his and his team's recent review article entitled "The biological significance of age, enhancement, extent of resection and tumor grade in IDH mutant gliomas: how should they inform treatment decision in the era of IDH inhibitors? Invited review", published online in Neuro-Oncology in

Dr. John Fortunato interviews Dr. Adrienne Boirre about her and her team's recent manuscript entitled "Leptomeningeal metastases from solid tumors: A SNO and ASCO consensus review on clinical management and future directions", published online in Neuro-Oncology on

Dr. Iyad Alnahhas interviews Drs. Justin Lathia and Marco Gallo about their recent manuscript entitled "Cancer stem cell hypothesis 2.0 in glioblastoma: where are we now and where are we going?", published online in Neuro-Oncology in May 2024.

Dr. Ankush Bhatia interviews Dr. Keaton Piper about his and his team's manuscript, entitled "Consensus Review on Strategies to Improve Delivery Across the BBB Including Focused Ultrasound", published online in Neuro-Oncology in May 2024 Read Paper

Dr. Evan Noch interviews Dr. Gunther Nussbaumer about his recent paper entitled: "Gliomatosis cerebri in children: a poor prognostic phenotype of diffuse gliomas with a distinct molecular profile" published online in Neuro-Oncology in May 2024.

Dr. Maya Graham interviews Drs. Josephine Hendriksen and Joachim Weischenfeldt about their recent manuscript, "Immunotherapy drives mesenchymal tumour cell state shift and TME immune response in glioblastoma patients," published online in Neuro-Oncology in May 2024.

Dr. Iyad Alnahhas interviews Drs. Alice Morin, Samuel Abbou and Brice Fresneau about their recent manuscript entitled "Very long-term outcomes of pediatric patients treated for optic pathway gliomas: a longitudinal cohort study" published online in Neuro-Oncology in March 2024. Read Paper

Dr. Rachna Malani interviews Dr. Hrishikesh Suresh about his and his team's recent manuscript entitled "Postoperative cerebellar mutism syndrome is an acquired Autism-like network disturbance", published online in Neuro-Oncology in December 2023. Read the paper

Dr. Evan Noch interviews Dr. Chunzhang Yang about his and his team's recent manuscript entitled "Abrogation of the G2/M checkpoint as a chemo sensitization approach for alkylating agents" published online in Neuro-Oncology in December 2023 Read Paper

Dr. Iyad Alnahhas interviews Dr. Ricardo Soffietti about the recent RANO review entitled "Liquid biopsy for improving diagnosis and monitoring of CNS lymphomas: a RANO review" published online in Neuro-Oncology in March 2024. Read the paper

Dr. John Fortunato interviews Dr. Antonio Chiocca about his and his team's recent manuscript entitled "Lessons learned from phase 3 trials of immunotherapy for glioblastoma: time for longitudinal sampling?" published online in Neuro-Oncology in February 2024. Get paper.

Dr. Maya Graham interviews Dr. Joseph Costello about his and his team's recent manuscript entitled "Whole tumor analysis reveals early origin of the TERT promoter mutation and intracellular heterogeneity in TERT expression", published online in Neuro-Oncology in December 2023.

Description: Dr. Maya Graham interviews Dr. Carl Koschmann about his and his team's recent manuscript entitled: "Liquid biopsy in H3K27M diffuse midline glioma", published online in Neuro-Oncology in December 2023. Download PDF

Dr. Iyad Alnahhas interviews Dr. Steven Tobochnik about his and his team's recent manuscript entitled "Glioma genetic profiles associated with electrophysiologic hyperexcitability", published online in Neuro-Oncology in Sep 2023. Read paper

Dr. Jasmin Jo interviews Dr. Harry Pinson about his and his team's recent manuscript entitled: "Epidemiology and survival of adult-type diffuse glioma in Belgium during the molecular era" Read Paper

Dr. Iyad Alnahhas interviews Dr. Amanda Saratsis about her recent manuscript entitled: "H3K27M Mutant Glioma: Disease Definition and Biological Underpinnings", published online in Neuro-Oncology in October 2023. Read Paper

Dr. Rachna Malani interviews Dr. Florian Scherer about his and his team's recent manuscript entitled: "Improved early outcome prediction by MRI-based 3D tumor volume assessment in patients with CNS lymphomas", published online in Neuro-Oncology in Sep 2023. Link: https://pubmed.ncbi.nlm.nih.gov/37713267/

Dr. John Fortunato interviews Drs. Edward Avila and Steven Tobochnik about their recent manuscript entitled: "Brain tumor-related epilepsy management: A society for neuro-oncology consensus review on current management", published online in Neuro-Oncology in June 2023. Read Paper

Description: Dr. Ankush Bhatia interviews Dr. Matthias Preusser about the recent letter in Neuro-Oncology, entitled: "What is an isocitrate dehydrogenase-mutated central nervous system World Health Organization grade 2 glioma, or who should receive vorasidenib?", published in July 2023.

Description: Dr. Maya Graham interviews Dr. Evan Noch about his and his team's recent manuscript entitled: "Insulin feedback is a targetable resistance mechanism of PI3K inhibition in glioblastoma", published online in Neuro-Oncology in July 2023. Read Paper

Dr. Evan Noch interviews Dr. David Solomon about his and his team's recent manuscript entitled: "Novel SOX10 indel mutations drive schwannomas through impaired transactivation of myelination gene programs", published online in Neuro-Oncology in July 2023. Read Paper

Dr. Iyad Alnahhas interviews Drs. Kelly Hotchkiss and Mustafa Khasraw about their recently published review entitled: "Dendritic cell vaccine trials in gliomas: untangling the lines", published online in Neuro-Oncology in June 2023. Read Paper

Dr. Iyad Alnahhas interviews Drs. Priya Kumthekar and Jeffrey Raizer about their recent manuscript entitled: A phase I/II study of intrathecal trastuzumab in human epidermal growth factor receptor 2-positive (HER2- positive) cancer with leptomeningeal metastases: Safety, efficacy, and cerebrospinal fluid pharmacokinetics", published online in Neuro-Oncology in March 2023.

Dr. Iyad Alnahhas interviews Drs. Maria Jose Contreras-Zarate and Diana Cittelly about their recent manuscript entitled: "Short-term topiramate treatment prevents radiation-induced cytotoxic edema in preclinical models of breast-cancer brain metastasis", published online in Neuro-Oncology in April 2023. Read Paper

Description: Dr. Maya Graham interviews Drs. Jasmin Jo, Craig Horbinski and David Schiff about their recent manuscript entitled: "Epidemiology, biology and management of venous thromboembolism in gliomas: an interdisciplinary review", published online in Neuro-Oncology in April 2023. Read Paper

Dr. Iyad Alnahhas interviews Dr. Philipp Karschnia about his and his team's recent manuscript entitled "Prognostic validation of a new classification system for extent of resection in glioblastoma: A report of the RANO resect group", published online in Neuro-Oncology in May 2023.

Dr. Evan Noch interviews Dr. David Kaul about his and his team's recent manuscript entitled: "Adult intracranial ependymoma—relevance of DNA methylation profiling for diagnosis, prognosis, and treatment", published online in Neuro-Oncology in February 2023. Read Paper

Dr. Ankush Bhatia interviews Dr.François Ducray about his and his team's recent manuscript entitled:"Incidence and characteristics of pseudoprogression in IDH-mutant high-grade gliomas: A POLA network study", published online in Neuro-Oncology in March 2023.

Dr. Iyad Alnahhas interviews Drs. Sherise Ferguson and Michael Davies about their recent manuscript entitled: "Changes in Outcomes and Factors Associated with Survival in Melanoma Patients with Brain Metastases", published online in Neuro-Oncology in December 2022. Read Paper

Dr. Evan Noch interviews Drs. Nikhil Rammohan and Kathleen Bandt about their recent manuscript entitled "Whole-brain radiotherapy associated with structural changes resembling aging as determined by anatomic surface-based deep learning", published online in Neuro-Oncology in February 2023. Read Paper

Dr. Maya Graham interviews Drs. Benjamin Ellingston and Timothy Cloughesy about their recently published manuscript entitled: "Objective response rate (ORR) targets for recurrent glioblastoma clinical trials based on the historic association between ORR and median overall survival", published online in Neuro-Oncology in January 2023. Read Paper

Dr. Iyad Alnahhas interviews Dr. Max Kros about his and his team's recent manuscript entitled: "Mitotic count is prognostic in IDH-mutant astrocytoma without homozygous deletion of CDKN2A/B. Results of consensus panel review of EORTC trials 26053 and EORTC 22033-26033", published online in Neuro-Oncology in December 2022. Read Paper

Dr. Iyad Alnahhas interviews Drs. Tobias Walbert and Johan Koekkoek about their recent manuscript entitled "Palliative care and end-of-life care in adults with malignant brain tumors", published online in Neuro-Oncology in October 2022 Read Paper

Description: Dr. Jasmin Jo interviews Dr. Michael Lim about his and his team's recent manuscript entitled: "Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter", published online in Neuro-Oncology in November 2022.

Description: Dr. Ankush Bhatia interviews Drs. Julie Miller, Nicolas Gonzalez Castro, Samuel McBrayer and Patrick Wen about their recent manuscript, entitled: "Isocitrate dehydrogenase (IDH) mutant gliomas: A Society for Neuro-Oncology (SNO) consensus review on diagnosis, management, and future directions", published online in Neuro-Oncology in October 2022. Full Report

Dr. Evan Noch interviews Drs. Richard Drexler and Franz Ricklefs about their recent manuscript entitled: "DNA methylation subclasses predict the benefit from gross total tumor resection in IDH-wildtype glioblastoma patients", published online in Neuro-Oncology in July 2022. Full Report

Description: Dr. Maya Graham interviews Drs. Gaia Ninatti and Martina Sollini about their recent manuscript entitled: "Pre-operative [11C]methionine PET to personalize treatment decisions in patients with lower-grade gliomas", published online in Neuro-Oncology in September 2022. Full Report

Dr. Iyad Alnahhas interviews Dr. David Gutmann about the review entitled "T lymphocytes as dynamic regulators of glioma pathobiology", published online in Neuro-Oncology in March 2022. Read paper

Dr. Evan Noch interviews Drs. Shannon Fortin Ensign and Sani Kizilbash about their recent paper in Neuro-Oncology entitled: "Translational significance of CDKN2A/B homozygous deletion in IDH mutant astrocytoma", published online in Neuro-Oncology in August 2022 Full Report

Dr. Maya Graham interviews Drs. Benjamin Lin, David Nathanson, Frank Furnari and Ryan Miller about their recent manuscript entitled: "EGFR, the Lazarus target for precision oncology in glioblastoma", published online in Neuro-Oncology in September 2022.

In this second of two episodes, Dr. Iyad Alnahhas interviews Drs. Ross Camidge, Michael Davis, Nancy Lin and Ayal Aizer about the recent editorial review entitled: "Brain Metastases: A Society for Neuro-Oncology (SNO) consensus review on current management and future directions", published online in Neuro-Oncology in June 2022. Full Report

In this first of two episodes, Dr. Iyad Alnahhas interviews Drs. Ayal Aizer, Eudocia Lee and Veronica Chiang about the recent editorial review entitled: "Brain Metastases: A Society for Neuro-Oncology (SNO) consensus review on current management and future directions", published online in Neuro-Oncology in June 2022. Full Report

Dr. Iyad Alnahhas interviews Drs. Jennifer Cotter and Kee Kiat Yeo about their recent paper entitled: ""Multi-institutional study of the frequency, genomic landscape and outcome of IDH-mutant glioma in pediatrics", published online in Neuro-Oncology in May 2022. Full Article

Dr. Jasmin Jo interviews Dr. Leland Rogers about his and his team's recent manuscript entitled: "Low-risk meningioma: initial outcomes from NRG Oncology/RTOG 0539", published online in Neuro-Oncology in June 2022 Full Article

Dr.Iyad Alnahhas interviews Drs. Andrea Gross and Brigitte Widemann about their manuscript entitled "Selumetinib in Children with Neurofibromatosis Type 1 and Asymptomatic Inoperable Plexiform Neurofibroma at Risk for Developing Tumor-Related Morbidity", published online in Neuro-Oncology in April 2022. Full Article

Dr. Evan Noch interviews Drs. Kee Kiat Yeo and Matthias Karajannis about their recent manuscript entitled: "Upfront molecular targeted therapy for the treatment of BRAF-mutant pediatric high grade glioma", published online in Neuro-Oncology in April 2022. Link to article

Description: Dr. Maya Graham interviews Dr. David Solomon about his and his team's recent manuscript entitled: "Prospective genomically-guided identification of "early/evolving" and "undersampled" IDH-wildtype glioblastoma leads to improved clinical outcomes", published online in Neuro-Oncology in April 2022. Read Article