Steroids and Insulin: The Hidden Trigger of Catastrophic Laminitis
Conversations in Equine Science
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Show Notes
In this episode Nancy McLean checks into recent equine herpes cases and focuses on new research linking corticosteroid (triamcinolone) joint injections to insulin spikes and severe laminitis. They review the case of Fiona, a competitive mare who developed fatal laminitis after sacroiliac injections, and summarize ongoing studies at NC State funded by the Chromatic Fund.
The researchers are comparing single high-dose versus repeated low-dose steroid protocols, finding undiagnosed insulin dysregulation in many sport horses and recommending insulin testing before steroid treatments. The clinical study is expected to conclude by spring 2026.