Treatment of Refractory Coccidioidomycosis in Dogs | VETgirl Veterinary Continuing Education Podcasts

In this VETgirl online veterinary continuing education podcast, we discuss the treatment of refractory coccidioidomycosis in dogs. Coccidioidomycosis, also known as Valley Fever, is a common fungal infection in the southwestern United States that is caused by the organisms Coccidioides immitis and Coccidioides posadasii. Pulmonary infections leading to fungal pneumonia are the most common presentation, though roughly a quarter of dogs will suffer from a disseminated infection, such as infection of the central nervous system and/or skeletal system (Johnson). Itraconazole and fluconazole are common first-line treatment choices, and treatment can be quite prolonged depending on the case. Unfortunately, some patients with this disease are refractory to standard antifungal treatment, and these dogs may require amphotericin B or other antifungal regimens. Additional therapeutic strategies are urgently needed for these patients!

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