Hypothyroidism and DCM in Doberman Pinschers | VETgirl Veterinary CE Podcasts

In today's VETgirl online veterinary continuing education podcast, we review whether or not there is an association between hypothyroidism and dilated cardiomyopathy (DCM). Doberman Pinschers are overrepresented among canine patients diagnosed with dilated cardiomyopathy (familial/genetic), as well as those diagnosed with hypothyroidism. So the question is, is there a link? This is a very controversial topic. After all, we know that thyroid hormone plays an important role in the systolic function of the myocardium and cardiac rate and rhythm via its effect on density of beta-adrenergic receptors and their sensitivity to catecholamines. A deficiency of thyroid hormone has been associated with reduced myocardial function and alterations in cardiac conduction and heart rate thus leading to the premise that the hypothyroid state may be a metabolic etiology for dilated cardiomyopathy. Studies to date have not supported that premise.