Burning questions on coagulation, thromboprophylaxis and hyperfibrinolysis with Alex Lynch and Rob Goggs - Part 1

Alex Lynch and Rob Goggs answer questions on indications for thromboprophylaxis, knowledge gaps in the area, if or when we should be more pro-active and ATE in cats. This is part 1 of 2. A selection of studies referred to: CURATIVE guidelines https://onlinelibrary.wiley.com/doi/epdf/10.1111/vec.12801 FAT CAT https://www.sciencedirect.com/science/article/pii/S1760273415000958 SUPERCAT https://avmajournals.avma.org/view/journals/javma/263/4/javma.24.09.0584.xml Characterisation of changes in the haemostasis system in dogs with thrombosis https://onlinelibrary.wiley.com/doi/10.1111/jsap.12037 CRASH 2 Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(10)60835-5/fulltext CRASH 3 Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)32233-0/fulltext WOMAN trial Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)30638-4/fulltext Rapid resolution of hyperfibrinolysis in dogs with spontaneous hemoperitoneum following surgical control of hemorrhage https://onlinelibrary.wiley.com/doi/full/10.1111/vec.13300