Genomics expert: does Covid mutation explain the Asia exception?
We spoke to David Engelthaler, co-director of the T-Gen Research Institute and former state epidemiologist of Arizona, about the 614G mutation
UnHerd with Freddie Sayers · Sebastian Giraud
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Show Notes
Freddie Sayers meets David Engelthaler, co-director of the T-Gen Research Institute and former state epidemiologist of Arizona.
Earlier this week, Freddie Sayers spoke to David Engelthaler, co-director of the T-Gen Research Institute and former state epidemiologist of Arizona, who has been investigating this idea. His view is that there is now “really compelling evidence” that this strain replicates faster than earlier strains, which "likely" came out of China and through to Europe. "It's really quickly dominated all of the other strains that were seen in Europe at the time, it became the predominant strain that came into the Americas, spread throughout the United States and is now spread to pretty much every corner of the planet".
In his own state, Engelthaler witnessed several of the early introductions to Arizona, coming from the Pacific coast straight from China, but fizzled out quickly, with less effective transmission. “And then all of a sudden we started having explosive outbreaks. When we go back and look genomically, the vast majority of those cases where we had very large outbreaks were being driven by the strains that were coming from the East Coast out of Europe, which all seemed to have this particular mutation in the spike protein.”
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