UEG Podcast

In this episode, Pradeep Mundre speaks with Hannah Gordon about one of the most challenging areas in inflammatory bowel disease management: balancing effective treatment with cancer risk. As therapeutic options expand, clinicians increasingly face complex scenarios involving patients with prior malignancy in remission or those undergoing active cancer treatment. The discussion examines how cancer risk relates both to IBD itself and to immunosuppressive or biologic therapies. The episode highlights limitations in current evidence, differences across drug classes, and the importance of individualised decision-making. Emphasis is placed on multidisciplinary collaboration, patient communication, and navigating uncertainty in real-world clinical practice.

Cristian Costas, a leading dietitian in coeliac disease, shares insights on managing celiac disease through diet, setting up specialised services, and navigating dietary challenges. We explore diagnosis, implementation of a gluten-free diet, and strategies to improve patient outcomes.

In the second part of this in-depth conversation, host Egle Dieninyte continues her discussion with Professor Nageshwar Reddy, shifting the focus from technological innovation to ethics, responsibility and the human dimension of endoscopy. Professor Reddy shares how mobile endoscopy units have brought life-saving care to rural populations, and why cascade hygiene strategies are sometimes necessary when resources are limited. The conversation then turns to a topic rarely discussed openly: mistakes. What constitutes a true medical mistake? How do we distinguish adverse events from preventable errors? And why should ERCP only ever be performed with strict indication? Finally, Professor Reddy reflects on mentorship, generational change, work–home balance, and why compassion is not an innate trait — but a skill that can and must be cultivated. A powerful conclusion to a two-part conversation on what it really means to practise endoscopy.

What has truly transformed endoscopy over the past decades? In this first part of a two-part conversation, host Egle Dieninyte sits down with Professor Nageshwar Reddy, one of the most influential pioneers in modern therapeutic endoscopy, to reflect on how the field has evolved — and where it is heading next. From the transition from rigid to fibreoptic endoscopy, to the introduction of video systems that reshaped team dynamics in the endoscopy suite, Professor Reddy explains why some of the most powerful innovations were not necessarily the most glamorous ones. The discussion also explores: • Disposable scopes and environmental responsibility • Antibiotic resistance and global practice differences • The role of passion and compassion in medicine • Regenerative endoscopy and stem cell applications • The story behind the “Nagi stent” Beyond technology, this episode offers a personal perspective on success, mentorship, and what it truly means to be a good endoscopist. 🎧 Listen now to Part 1 — and stay tuned for Part 2, which will be released in a week from now on the 4th of March.

- What happens when optical diagnosis and histology don’t align? - Does better polyp detection always mean better outcomes? - And how should AI, quality metrics and surveillance intervals really shape daily endoscopy practice? In this special episode, we share an unfiltered round-table discussion recorded during the UEG Online Course on the impact of polyp detection in colonoscopy. Leading experts Raf Bisschops, Manuele Furnari, Veronique Van der Voort and Pieter Sinonquel debate real-world dilemmas around serrated lesions, pathology discordance, documentation, bowel preparation and the clinical consequences of rising ADRs. Also watch it as a video podcast on Spotify Listen now and explore the full course for free (login required) on gutflix.eu: [The impact of polyp detection in colonoscopy](https://gutflix.eu/r/i6GfsYAhus8u)

In this episode of the UEG Podcast, host Pradeep Mundre is joined by David Sanders, Professor of Gastroenterology at Sheffield and one of the world’s leading experts in coeliac disease. Timed with the recent update of the British Society of Gastroenterology coeliac guidelines, the discussion explores why coeliac disease remains frequently underdiagnosed, even in specialist care. Together, they unpack the latest evidence on serology-based diagnosis, optimal biopsy strategies, potential and seronegative coeliac disease, and when HLA testing is truly useful. The episode also covers long-term follow-up, the role of repeat biopsies, ultra-short coeliac disease, and emerging non-dietary therapies — including the realistic prospects of a future “pizza pill”. Check out the newest guidelines on coeliac disease here:https://doi.org/10.1002/ueg2.70119