Triangulation (Audio)

In a wide-ranging conversation, Leo Laporte talks with Dr. George Church about the history and future of genome sequencing. Dr. Church explains why he is very excited about how they made an organism resistant to all viruses- both known and unknown. They also talk about: How Dr. Church made sequencing affordable (from $3BN to $600) Where are we on sequencing the entire human genome, and why would we even want to? How close are we to reversing aging? Should we use gene therapy to double the human lifespan? Why genetically engineering cold-resistant elephants could be important for climate change, and what about ultimately bringing back the Mammoth? He explains the difference between the hype and reality of CRISPR sequencing, synthesis, and delivery What are the privacy concerns about companies sharing your genome? They discuss the controversy and benefit of reconstructing old viruses like the 1918 flu and even inventing new viruses. Dr. Church is a professor of genetics at Harvard Medical School and a pioneer in personal genetics. He is credited with developing the first methods for sequencing the first genome and also the CRISPR technology. He created several companies, including Nebula Genomics and Veritas Genetics. Host: Leo Laporte Guest: Dr. George Church Download or subscribe to this show at https://twit.tv/shows/triangulation.

New York Times bestselling author Daniel Suarez returns to talk with Leo Laporte about the second book in his 'Delta-v' novel series, 'Critical Mass,' where a group of pioneering astropreneurs must overcome never-before-attempted engineering challenges to rescue colleagues stranded at a distant asteroid—kicking off a new space race in which Earth's climate crisis could well hang in the balance. Get 'Critical Mass': https://amzn.to/3Yjb9xu Host: Leo Laporte Guest: Daniel Suarez Download or subscribe to this show at https://twit.tv/shows/triangulation.

Writer/activist Cory Doctorow and scholar Rebecca Giblin join Leo Laporte to talk about their latest book Chokepoint Capitalism: How Big Tech and Big Content Captured Creative Labor Markets and How We'll Win Them Back. They argue that we're in a new era of "chokepoint capitalism," with exploitative businesses creating insurmountable barriers to competition that enable them to capture value that should rightfully go to others. Get "Chokepoint Capitalism": https://chokepointcapitalism.com Host: Leo Laporte Guests: Cory Doctorow and Rebecca Giblin Download or subscribe to this show at https://twit.tv/shows/triangulation.

Tripp Mickle joins Leo Laporte to discuss his new book, "After Steve: How Apple Became a Trillion-Dollar Company and Lost Its Soul". They discuss the shift in Apple's dynamic and approach to products after the passing of Steve Jobs from a company of innovation with Jony Ive, to a company of efficiency under Tim Cook. Host: Leo Laporte Guest: Tripp Mickle Download or subscribe to this show at https://twit.tv/shows/triangulation.

Amy Webb joins Leo Laporte to discuss her new book, "The Genesis Machine." Webb explains synthetic biology, tells the story of golden rice, and shares a glimpse of the future and the changes we can expect. Get "The Genesis Machine": https://amzn.to/3BC7K2t Host: Leo Laporte Guest: Amy Webb Download or subscribe to this show at https://twit.tv/shows/triangulation.

Leo Laporte interviews Andy Weir, author of "The Martian," about his new book, "Project Hail Mary." The discussion starts out spoiler-free with a chat about making the book into a film, how Andy Weir approached writing this book, and the time he confused Ryan Reynolds and Ryan Gosling. After a loud and apparent spoiler warning (at 32:04), the two continue their chat by discussing "Project Hail Mary" in depth. Weir shares a bit about the science behind the book, the characters he's created, and other stories he's working on. Project Hail Mary: https://amzn.to/3hLcStp The Martian: https://amzn.to/3v9LUiU Artemis: https://amzn.to/3vahYDf Host: Leo Laporte Guest: Andy Weir Download or subscribe to this show at https://twit.tv/shows/triangulation.

Jason Howell is joined by TWiT's studio engineer to talk about his time as the drummer and founder of the progressive rock band Cairo, creating the Virtual Live Show, and how the intersection of music and tech has evolved. Cairo on YouTube: https://www.youtube.com/JeffBrockmanDirector Virtual Live Show on Twitter: https://twitter.com/virtualliveshow Host: Jason Howell Guest: Jeff Brockman Download or subscribe to this show at https://twit.tv/shows/triangulation.

Flynn Coleman, writer, and international human rights attorney, joins Denise Howell to talk about her book A Human Algorithm: How Artificial Intelligence Is Redefining Who We Are. Flynn argues that we must instill values, ethics, and morals into our robots, algorithms, and other forms of AI by developing and implement laws, policies, and oversight mechanisms to protect us from tech's insidious threats. Get "A Human Algorithm": https://amzn.to/2rIqgH6 Host: Denise Howell Guest: Flynn Coleman Download or subscribe to this show at https://twit.tv/shows/triangulation.

Stephen Wolfram is a computer scientist who designed Mathematica, Wolfram Alpha, and the Wolfram Language. He talks to Mikah Sargent about translating between human language, mathematics, and programming languages, how computational language works, and how he has spent his life trying to build computational intelligence up. Host: Mikah Sargent Guest: Stephen Wolfram Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsors: capterra.com/triangulation LastPass.com/twit

Margaret O'Mara, Professor of History at the University of Washington, joins Mikah Sargent to talk about her book The Code: Silicon Valley and the Remaking of America. They dive into the behind-the-scenes history of Silicon Valley, including how the Cold War shaped what Stanford University is today, shine a light on some of the unsung heroes like Ann Hardy and David Morgenthaler, and the legacy of Steve Jobs. Get "The Code": https://amzn.to/32ozIwm Host: Mikah Sargent Guest: Margaret O'Mara Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: LastPass.com/twit

Scott Petry is the CEO of Authentic8. He talks to Leo Laporte about his work on the Newton, how he saved the world from spam, and his plan to make your browser safe. Host: Leo Laporte Guest: Scott Petry Download or subscribe to this show at https://twit.tv/shows/triangulation.

Brett Frischmann is the Charles Widger Endowed University Professor in Law, Business and Economics, Villanova University and joins Denise Howell to discuss his book, co-authored with Evan Selinger, "Re-Engineering Humanity." They talk about what's happening to our lives as society embraces big data, predictive analytics, and smart environments. Host: Denise Howell Guest: Brett Frischmann Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: capterra.com/triangulation

Famed writer, comedian, and actor John Hodgman (though not nearly as those two corgis from Instagram) returns to join Mikah Sargent to discuss his latest book Medallion Status: True Stories from Secret Rooms. They examine status, fame, and identity; and dive into how to make the perfect hard-boiled egg, how a nude scene with an oboe relates to vulnerability, and how celebrity has evolved. Get "Medallion Status": https://amzn.to/36picuc Host: Mikah Sargent Guest: John Hodgman Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: ZipRecruiter.com/triangulation

Yancey Strickler is the co-founder and former CEO of Kickstarter and joins Jason Howell to talk about his new book, This Could Be Our Future: A Manifesto for a More Generous World. They discuss the crowdfunding platform's transition into a public-benefit corporation, leading to Yancey's book, which details a philosophy and framework for building a society that looks beyond "financial maximization" and more towards other values like community, purpose, and sustainability. Buy "This Could Be Our Future": https://amzn.to/2JlMhkx Host: Jason Howell Guest: Yancey Strickler Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: LastPass.com/twit

Jeri Ellsworth returns to talk with Jason Howell about Tilt Five's holographic tabletop gaming system, what happened with her previous augmented reality startup castAR, and the how the AR/VR space has evolved and where it's going. Host: Jason Howell Guest: Jeri Ellsworth Download or subscribe to this show at https://twit.tv/shows/triangulation.

Ruha Benjamin, Associate Professor of African American Studies at Princeton University, joins Mikah Sargent to talk about her new book "Race After Technology: Abolitionist Tools for the New Jim Code." They discuss how emerging technologies can reinforce and amplify racial biases and ways we could solve this problem. Buy "Race After Technology": https://amzn.to/2Bj8ICE Host: Mikah Sargent Guest: Ruha Benjamin Download or subscribe to this show at https://twit.tv/shows/triangulation.

Mikah Sargent talks with professor Kate O'Neill about her new book, "Waste" and what we can do about the ever-growing amount of trash each of us produces. They discuss what happens to much of our e-waste and how tech companies could work proactively, including the right-to-repair. One big issue is how China changed recycling world-wide, complicating the recycling industry and what happens next. Some solutions to this problem include finding alternatives to plastic and developing a global solution to our waste problem. Mikah and Kate also coin the term "Garbology." Buy "Waste": https://amzn.to/2luYrPt Host: Mikah Sargent Guest: Kate O'Neill ("Waste" author) Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: LastPass.com/twit

Best known for developing the sleep-aid app White Noise, Todd Moore is an app developer, founder and CEO of TMSOFT, and author of Tap, Move, Shake. Todd joins Ant Pruitt to discuss his advice for app devs, the differences in developing for iOS and Android, and working on new platforms like AR/VR and virtual assistants. Get White Noise: https://www.tmsoft.com/white-noise/ Buy "Tap, Move, Shake": https://amzn.to/2nPfyw4 Host: Ant Pruitt Guest: Todd Moore Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: capterra.com/triangulation

Shel Israel is a writer, consultant, and expert on how technology is shaping humanity. He talks with Denise Howell about how the development of Artificial Intelligence is affecting driving, education, and even dentistry. Host: Denise Howell Guest: Shel Israel Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: ZipRecruiter.com/triangulation

Jono Bacon is the author of "People Powered: How Communities can Supercharge your Business, Brand, and Teams." He talks with Leo Laporte about how to grow your community by facilitating safe, constructive feedback. Host: Leo Laporte Guest: Jono Bacon Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsors: ZipRecruiter.com/triangulation capterra.com/triangulation

Mikah Sargent speaks with David Weinberger, author of Everyday Chaos: Technology, Complexity, and How We're Thriving in a New World of Possibility about how AI, big data, and the internet are all revealing that the world is vastly more complex and unpredictable than we've allowed ourselves to see and how we're getting acculturated to these machines based on chaos. Buy "Everyday Chaos": https://amzn.to/2ZMPHSY Host: Mikah Sargent Guest: David Weinberger Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: ZipRecruiter.com/triangulation

Randall Munroe is the creator of the greatest comic strip on the internet: XKCD, and the author of the new book How To: Absurd Scientific Advice for Common Real-World Problems. He talks with Leo Laporte about how he got started making comic strips, the importance of not making fun of people for not knowing stuff, and the best way to generate letter pairs for kerning. Buy "How To": https://amzn.to/2ZzxGLM Host: Leo Laporte Guest: Randall Munroe Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: ZipRecruiter.com/triangulation

Yan Zhu, AKA bcrypt, is the Chief Security Officer at Brave. Yan joins Leo Laporte to talk about her past dropping out of high school and earning a B.S. at MIT; her work on Brave's security-focused browser and other open-source projects like HTTPS Everywhere, SecureDrop, and Privacy Badger on Firefox; DJing and creating electronic music; and more. Host: Leo Laporte Guest: Yan Zhu Download or subscribe to this show at https://twit.tv/shows/triangulation.

Bryan Walsh is the author of End Times: A Brief Guide to the End of the World. He talks with Mikah Sargent about the many, many ways Mother Earth may try to kill us all and the ways we might beat her to it. He also gives some hope for the future. Host: Mikah Sargent Guest: Bryan Walsh Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: capterra.com/triangulation

Ed Niedermeyer is the author of Ludicrous: The Unvarnished Story of Tesla Motors. He talks to Leo Laporte about how Tesla has succeeded, how it has failed, and what it needs to do to win. Host: Leo Laporte Guest: Ed Niedermeyer Download or subscribe to this show at https://twit.tv/shows/triangulation.

Jason Howell speaks with Andrew Maynard, professor in the Arizona State University School for the Future of Innovation in Society, about his book Films from the Future: The Technology and Morality of Sci-Fi Movies. They dive into his book discussing whether sci-fi films like Jurassic Park, Limitless, Ghost in the Shell, and Ex Machina is predicting or creating our future, responsible innovation, what Andrew finds really disturbing about AI, the ethics of Elon Musk's Neuralink technology, and more. Buy "Films from the Future": https://amzn.to/2T3ORiT Host: Jason Howell Guest: Andrew Maynard Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: capterra.com/triangulation

Denise Howell speaks with independent writer, digital governance expert, and open government advocate Alex Howard. They discuss the 'Post-truth' era, the Honest Ads Act that he helped draft due to the lack of transparency for political ad spending online, how the ways politicians and governments use social media matters, the issues of content moderating, Facebook's $5 billion fine from the FTC over privacy breaches, and more. Host: Denise Howell Guest: Alex Howard Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: ZipRecruiter.com/triangulation

BitTorrent creator Bram Cohen returns to 'Triangulation' with Jason Howell to talk about Chia Network and how they are creating an open-source blockchain which is a more decentralized and energy-efficient cryptocurrency than Bitcoin. They also discuss Facebook's Libra, where President Trump is right and wrong on crypto and Bram's other hobby as a puzzle maker. Host: Jason Howell Guest: Bram Cohen Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsors: capterra.com/triangulation ZipRecruiter.com/triangulation

Trey Ratcliff, author of "Under the Influence," talks with Leo Laporte about the bane of Instagram "Influencers," how to turn criticism into creativity, and how to survive on social media without losing your soul. Buy "Under the Influence": https://amzn.to/2LDi3vu Host: Leo Laporte Guest: Trey Ratcliff Download or subscribe to this show at https://twit.tv/shows/triangulation.

Jason Howell speaks with journalist, researcher, and co-director of the Center for the Study of the Drone at Bard College Arthur Holland Michel about his new book "Eyes in the Sky: The Secret Rise of Gorgon Stare and How It Will Watch Us All." They dive into how the film "Enemy of the State" influenced the Pentagon to develop a high-tech aerial surveillance system for monitoring America's enemies overseas, how the Wide Angle Motion Imagery tech is now being used to watch US citizens, and more. Buy "Eyes in the Sky": https://amzn.to/2Y4g3jd Host: Jason Howell Guest: Arthur Holland Michel Download or subscribe to this show at https://twit.tv/shows/triangulation.

Leo Laporte speaks with Jigsaw's Chief Operating Officer Dan Keyserling. They discuss how the incubator, which began as Google Ideas, is working to make the world a better place by building technologies to help fight attacks on free speech, online harassment, violent extremism, and other injustices with projects like Project Shield, Password Alert, Conversation AI, Digital Attack Map, Outline, Share the Facts, and more. Host: Leo Laporte Guest: Dan Keyserling Download or subscribe to this show at https://twit.tv/shows/triangulation.

Megan Morrone speaks with journalist and author Julian Guthrie about her latest book, Alpha Girls: The Women Upstarts Who Took On Silicon Valley's Male Culture and Made the Deals of a Lifetime. They discuss why Julian decided to tell the stories of these four pioneering women in the male-dominated world of Silicon Valley (Theresia Guow, Magdalena Yeşil, MJ Elmore, and Sonja Perkins), some key lessons and regrets from these entrepreneurs, how sexist attitudes have evolved in tech and other industries where women are underrepresented, how the book is being adapted into a television series, and more. Buy "Alpha Girls": https://amzn.to/2WXeuqE​ Host: Megan Morrone Guest: Julian Guthrie Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: capterra.com/triangulation

Jason Howell speaks with investigative reporter and author Joseph Menn about his latest book, Cult of the Dead Cow: How the Original Hacking Supergroup Might Just Save the World. They discuss how the origins of the famous hacking group and its impact on society, how many of these hacktivists have become powerful public figures, how Joseph uncovered presidential candidate Beto O'Rourke as a member, and more. Buy "Cult of the Dead Cow": https://amzn.to/2WvaihA Host: Jason Howell Guest: Joseph Menn Download or subscribe to this show at https://twit.tv/shows/triangulation.

Denise Howell speaks with the driving force behind San Francisco's facial recognition ban and Executive Director of Secure Justice, Brian Hofer. They discuss the state of facial recognition technology, the reasoning behind the ban, how the mission creep of mass surveillance technologies affect civil liberties, and more. Host: Denise Howell Guest: Brian Hofer Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: The Intrazone

Megan Morrone speaks with Jessica Powell, Google's former VP of Communications and author of The Big Disruption: A Totally Fictional But Essentially True Silicon Valley Story. They discuss how she came about to writing this satirical novel about tech, becoming Medium's first print book, the impact of Silicon Valley's monoculture, and more. Buy 'The Big Disruption': https://amzn.to/2K4o1EW Host: Megan Morrone Guest: Jessica Powell Download or subscribe to this show at https://twit.tv/shows/triangulation.

NYT bestselling author Daniel Suarez returns to talk with Leo Laporte about his latest book Delta-v, a near-future technological thriller following the first deep space mining operation. Buy Delta-v: https://amzn.to/2VuqmuF Host: Leo Laporte Guest: Daniel Suarez Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsors: Behind the Tech ZipRecruiter.com/triangulation

Jason Howell speaks with Brianna Wu, video game developer and Candidate for US House of Representatives in MA District 8 for 2020. They discuss how she got started in tech, surviving the Gamergate harassment, why she's running for Congress, and more. Host: Jason Howell Guest: Brianna Wu Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: capterra.com/triangulation

Cory Doctorow's latest book is Radicalized. Megan Morrone talks to him about DRM toast, online radicalization and science fiction vs. futurism. Buy Radicalized: https://amzn.to/2VdUejR Host: Megan Morrone Guest: Cory Doctorow Download or subscribe to this show at https://twit.tv/shows/triangulation.

Celia Hodent is a cognitive scientist, game industry veteran, and author of The Gamer's Brain: How Neuroscience and UX can Impact Video Game Design. She talks with Denise Howell about common misconceptions on how the brain works, how games like Fornite use cognitive science to create an engaging experience, the problem with the term 'gaming addiction,' when loot boxes become gambling, and more. Buy 'The Gamer's Brain': https://amzn.to/2GAopsu Host: Denise Howell Guest: Celia Hodent Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: The Intrazone

Megan Morrone speaks with Leander Kahney, the editor and publisher of CultofMac.com and author of Inside Steve's Brain, Jony Ive: The Genius Behind Apple's Greatest Products, and Cult of Mac, about his latest book, Tim Cook: The Genius Who Took Apple to the Next Level. They discuss Tim's background and how he started at Apple, how Cook fixed Apple's supply chain with just-in-time manufacturing, and the clash between Apple and the FBI over iPhone encryption, and more. Host: Megan Morrone Guest: Leander Kahney Download or subscribe to this show at https://twit.tv/shows/triangulation.

Mark Richards is a photojournalist and photographer of "Core Memory: A Visual Survey of Vintage Computers." He talks with Leo Laporte about his career including photographing combat in Afghanistan, chronicling his cancer treatment and preserving computer history. Host: Leo Laporte Guest: Mark Richards Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsors: ZipRecruiter.com/triangulation capterra.com/triangulation

Denise Howell speaks with author Kate O'Neill, "The Tech Humanist", about her new book, "Tech Humanist: How You Can Make Technology Better for Business and Better for Humans." They discuss her background, she was one of the first 100 employees at Netflix, her viral Tweets and article on the Ten Year Challenge, as well as reports that IBM used photos from millions of Flickr users, without their consent or knowledge, to train its facial recognition tech, and more. Host: Denise Howell Guest: Kate O'Neill (Tech Humanist) Download or subscribe to this show at https://twit.tv/shows/triangulation.

Charlie Jane Anders is the author of The City in the Middle of the Night. She talks with Megan Morrone about starting the sci-fi blog iO9, the difference between futurism and science fiction, and writing believable characters who screw up. Host: Megan Morrone Guest: Charlie Jane Anders Download or subscribe to this show at https://twit.tv/shows/triangulation.

Denise Howell speaks with lawyer and MyCase Legal Technology Evangelist Nicole Black. They discuss the NYPD's demand that Waze removes user-submitted reports on speed traps and DWI checkpoints, whether biometric access to phones requires a warrant, false friends in law enforcement, sex offenders and the first amendment, AI in the legal profession, the darker side of Instagram, and more. Host: Denise Howell Guest: Nicole Black Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsors: capterra.com/triangulation ZipRecruiter.com/triangulation

Jason Howell speaks with returning guest Blake Harris, author of the bestseller Console Wars, about his latest book, The History of the Future: Oculus, Facebook, and the Revolution That Swept Virtual Reality. They discuss Harris' three-plus years chronicling the meteoric rise of Oculus, the VR company founded by Palmer Luckey in 2012 that was acquired for over $2 billion dollars only two years later; and how he, after being systematically lied to by Facebook executives, uncovered the true story that led to the controversial firing of Luckey. Host: Jason Howell Guest: Blake Harris Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: capterra.com/triangulation

Can we live without big tech? Is it even possible to avoid any influence when they dominate the internet today? Megan Morrone speaks with Gizmodo's investigative reporter Kashmir Hill about her six weeks blocking Google, Amazon, Facebook, Microsoft, and Apple from monetizing her in any way whether through surveillance capitalism or using any of their products. Host: Megan Morrone Guest: Kashmir Hill Download or subscribe to this show at https://twit.tv/shows/triangulation.

Amy Webb is the Author of The Big Nine: How the Tech Titans & Their Thinking Machines Could Warp Humanity. She talks with Leo Laporte about the coming age of artificial intelligence and the nine companies that will control it. Host: Leo Laporte Guest: Amy Webb Download or subscribe to this show at https://twit.tv/shows/triangulation.

Flickr Co-Founder and Yes VC Partner Caterina Fake joins the show for the third time to talk about her new podcast Should This Exist? which is about how technology is impacting our humanity. Jason Howell and Caterina discuss the struggle of ethics in the tech, the difficulty in foreseeing the minefield of unintended consequences, if government regulation has a role keeping tech companies in check, and more. Plus, Jason gives Caterina a 'should this exist?' lighting round with pet cloning, designer babes, and deep fakes. Host: Jason Howell Guest: Caterina Fake Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: ZipRecruiter.com/triangulation

Jason Howell is joined by Dr. Joel Sadler, founder of the education startup Piper. They discuss their latest DIY computer kit which teaches kids to build and program electronics; launching their first kit on Kickstarter, trojan horse-learning with Minecraft, STEM education in the classroom, and more. Host: Jason Howell Guest: Dr. Joel Sadler Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: capterra.com/triangulation

Denise Howell is joined by Tom W. Bell, who is a professor at Chapman University, Fowler School of Law, and author of Your Next Government?: From the Nation State to Stateless Nations. They discuss off-the-shelf government and open-source legal systems like Ulex, big tech stepping into roles traditionally occupied by government, seasteading, the future of cryptocurrency, and more. Host: Denise Howell Guest: Tom W. Bell Download or subscribe to this show at https://twit.tv/shows/triangulation. Sponsor: ZipRecruiter.com/triangulation