TWiV 796: The vary hungry spike with Paul and Theodora
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Show Notes
Paul and Theodora return to TWiV to explain their research on determining the number of neutralizing epitopes on the SARS-CoV-2 spike that are recognized by antibodies, and engineering of a polymutant spike with twenty amino acid changes that demonstrates the high genetic barrier to escape from convalescent serum.
Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker
Guests: Paul Bieniasz and Theodora Hatiziiouannou
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Links for this episode- High genetic barrier for SARS-CoV-2 antibody escape (bioRxiv)
- Enhanced antibody one year after COVID-19 (Nature)
- Letters read on TWiV 796
- Timestamps by Jolene. Thanks!
Dickson – NIF and Photon Science: fusion reaction generates 1.3 MJ Brianne – The PCR Song Rich – 1) How Boston Dynamics' Spot Robot Works! 2) Inside the lab: How does Atlas work?3) Atlas | Partners in Parkour Theodora – Kevin Parry turning into random objects Vincent – Lex Fridman
Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]