TWiV 1242: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello re-address the dangers of drinking raw milk, the Legionnaire’s outbreak in Harlem and results of a vaccine knowledge survey done by emergency departments before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, reports of influenza-associated acute necrotizing encephalopathy or neuropsychiatric events in children, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the effectiveness of Pfizer and MODERNA vaccines against the JN.1 variant, risk of children developing severe disease from SARS-CoV-2 infection, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, the association of “virus rebound” and post-acute sequelae among hospitalized patients, effectiveness of COVID-19 vaccines against long COVID, predictors for distinct COVID-19 sequelae including immune disturbances and contacting your federal government representative to stop the assault on science and biomedical research.

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Links for this episode

• Florida Department of Health Provides Update on Raw Milk(Florida Health)
• Raw milk linked to 21 E coli, Campylobacter infections in Florida (CIDRAP)
• Legionnaires’ Disease: In Harlem (NYC Health)
• NYC health officials report Harlem Legionnaires’ outbreak(CIDRAP)
• Emergency Department Survey of Vaccination Knowledge, Vaccination Coverage, and Willingness to Receive Vaccines in an Emergency Department Among Underserved Populations  (CDC: MMWR)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola) Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Influenza-Associated Acute Necrotizing Encephalopathy in US Children (JAMA)
• Influenza With and Without Oseltamivir Treatment and Neuropsychiatric Events Among Children and Adolescents(JAMA Neurology)
• FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• ENFLONSIA: novel drug approvals 2025 (FDA)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Effectiveness of the BNT162b2 and mRNA-1273 JN.1-adapted vaccines against COVID-19-associated hospitalisation and death: a Danish, nationwide, register-based, cohort study (LANCET: Infectious Diseases)
• Hospitalization for COVID-19 and Risk Factors for Severe Disease Among Children: 2022–2024 (Pediatrics)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Metformin and Time to Sustained Recovery in Adults With COVID-19 (JAMA Internal Medicine)
• Drug interaction checker (University of Liverpool)
• Paxlovid (Pfizer)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• SARS-CoV-2 rebound and post-acute mortality and hospitalization among patients admitted with COVID-19(Nature Communications)
• Steroids,dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin’s evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Effectiveness of COVID-19 vaccines against post COVID-19 condition/long COVID (CMI: Clinical Microbiology and Infection)
• Precision Symptom Phenotyping Identifies Early Clinical and Proteomic Predictors of Distinct COVID-19 Sequelae (JID)
• Systemic and SARS-CoV-2 specific Immune Disturbances in Individuals With Post–COVID Syndrome (JID)
• Reaching out to US house representative
• Letters read on TWiV 1242
• Dr. Griffin’s COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

Content in this podcast should not be construed as medical advice.