TWiP 222: Balamuthia in the brain with Natasha Spottiswoode
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Show Notes
At the meeting of the American Society for Tropical Medicine and Hygeine in Chicago, Natasha joins TWiP to solve the case of the Man with a Generalized Seizure and Infectious Forms in the Brain.
Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula
Guest: Natasha Spottiswoode
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Links for this episode- Treatment of Balamuthia encephalitis with nitroxoline (Emerg Inf Dis)
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Case Study for TWiP 222
Haitian creole speaking, cachetic female in her 50s w/ hx HIV (noncompliant on medication), migrating from Haiti brought in by her daughter for dysphagia, cough x days, associated with NBNB vomiting, oral thrush extending to soft palate, concerning for oropharyngeal candidiasis. Weeks of nonresolving diarrhea. Admitted for failure to thrive and deconditioning, found to be Parainfluenza 3 positive), undergoing TB rule out. Diarrhea is voluminous, pt is dehydrated, there has been significant weight loss and lethargy over the last few weeks.
MHx:
HIV
Shx:
Lives in haiti
Remarried, Last sexual encounter 2 years ago.
Denies illicit drug use. Drinks alcohol
Allergies: No Active Allergies
Labs return with CD4 count in the 50s, elevated viral load. CD4 55/3%
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Music by Ronald Jenkees