This Week in Cardiology

The EXCEL debate, the NOBLE trial, alcohol and AF, cardiac devices, and hospital consolidation are the topics covered by John Mandrola, MD, in this week's podcast.

A risk score for device infection, conflicts of interest, the Fragility Index, rhythm vs rate control for AF in HFpEF, and year-end highlights are discussed by John Mandrola, MD, in this week's podcast.

The EXCEL trial controversy, and Dr John Mandrola's experience with vernakalant at FDA are the topics covered in this week's podcast.

Vernakalent, CV death in cancer patients, dapagliflozin, and sacubitril/valsartan are the topics Dr. John Mandrola discusses in this week's podcast.

Highlights from the 2019 AHA meeting are analyzed by Dr John Mandrola in this week's podcast.

Interruption of oral anticoagulation, marijuana and stroke, ORBITA substudy, ISCHEMIA medical therapy targets, and more on AHA are the topics discussed by Dr. John Mandrola in this week's podcast.

Words that harm, statins, thyroid replacement, and the ISCHEMIA trial are the topics discussed by Dr John Mandrola in this week's podcast.

Mortality after AF ablation, cardiac rehab programs, hypertrophic cardiomyopathy, and clinician wellness are the topics Dr. John Mandrola discusses in this week's podcast.

AF after TAVR, opioids after cardiac devices, hypertension in black adults, and post-cardiac surgery AF are the topics Dr John Mandrola discusses in this week's podcast.

The Nobel Prize, more on the EXCEL trial, the costs of cardiac tests, familial hypercholesterolemia, and burnout are the topics discussed by Dr John Mandrola in this week's podcast.

Left main PCI vs CABG trials and TAVR vs SAVR—in this week's podcast, Dr John Mandrola takes a deeper dive.

Social effects of medicine, SGLT2 inhibitors, CIED infections, equity in cardiology, and post-PCI anti-thrombotic therapy are the topics discussed by Dr John Mandrola in this week's podcast.

The polypill, dapagliflozin, TAVR, and video games are discussed by John Mandrola, MD, in this week's podcast.

More from ESC: Antiplatelets and NOACs, blood glucose control, high sensitivity troponin tests, and ICD trials are all covered by John Mandrola, MD, in this week's podcast.

Six major trials from the ESC meeting in Paris are reviewed by John Mandrola, MD, in this week's podcast.

Digital health, a new LDL-c lowering drug, PCSK9i outcomes in higher risk patients, and an ESC preview are discussed by John Mandrola in this week's podcast.

TAVR, baroreflex activation for heart failure, dapagliflozin for HF, and myocardial viability are the topics discussed by John Mandrola in this week's podcast.

AI for AF detection, syncope and PE, thoracentesis, fish oil, and why doctors should organize are the topics covered by John Mandrola in this week's podcast.

Digoxin, acupuncture and angina, heart failure with preserved ejection fraction, bariatric surgery, and cardiac device complications are the topics John Mandrola covers in this week's podcast.

CRT in patients with non-LBBB, ezetimibe, lifestyle diseases in the young, end of life care, and diabetes for the cardiologist are the topics John Mandrola, MD discusses in this week's podcast

Deprescribing beta bockers, interrupting oral anticoagulants, sudden death, quality measures, and acute stroke care are the topics John Mandrola, MD discusses in this week's podcast.

High-sensitivity troponin assays, nursing education, negative risk markers, valve-in-valve TAVRs, and the use of AI in medical practice are covered in this week's podcast.

Medical reversals, conflict of interest in the cardiac cath lab, cardiologist burnout, and changes in TAVR rules are discussed by John Mandrola, MD, in this week's podcast.

FDA hearings on paclitaxel devices in PAD, health news spin, myocarditis, difficult conversations, and TAVR in patients with end stage renal disease (ESRD) are discussed in this week's podcast.

Vitamin D, ICD in patients on dialysis, aspirin, type 2 diabetes, and paclitaxel in PAD are the topics covered by John Mandrola in this week's podcast.

Complications of PCI, health hubs, AV block after TAVR, VTE prevention, and rivaroxaban use in patients with heart failure are the topics discussed by Dr John Mandrola in this week's podcast.

Tricuspid valve repair, aortic stenosis, His-bundle pacing, deprescribing loop diuretics, and 'leakage' are covered in this week's podcast.

Aspirin and ICH, late tPA for stroke, public reporting of outcomes, Impella, grapefruit juice and QT interval, and ICDs for primary prevention are discussed in this week's podcast.

Renal and AF ablation in combination, infection risk of devices, neuromodulation of AF, pulsed field ablation and stroke of unknown source are covered in a HRS-heavy podcast.

Spin in the cardiovascular literature, palliative care for cardiac patients, tPA for acute stroke, and whether institutional volume affects AF ablation complications are the topics discussed this week.

Bike commuting and obesity, CMR for NSTEMI, Niacin in secondary prevention, cardiologists' pay, and end-of-life conversations are in this week's podcast.

Anticoagulation for embolic stroke of unknown origin, added-sugar labels, AF-patient knowledge, LDL-C and hemorrhagic stroke, and genetic signals in cancer-care cardiomyopathy are discussed this week.

Super-saturated oxygen in STEMI, Medicaid expansion and CV mortality, pacemakers in patients with HFpEF, HF readmissions, and exercise vs diet for weight loss are discussed in this week's podcast.

ARB recalls, bystander compression-only CPR, renal denervation for hypertension, LDL cholesterol targets, and pre-op frailty are the topics discussed in this week's podcast.

Catheter ablation for atrial fibrillation, eggs, booze, and anti-thrombotic agents for double vs triple therapy in patients with ACS and AF are discussed in this week's podcast.

From ACC.19 and EHRA: The Apple Heart study, TAVR for low-surgical-risk AS, preventing cardiac device infections, COACT, VF arrest, and AF cardioversion are discussed in this week's podcast.

Obesity paradox studies and collider bias, the ISCHEMIA trial baseline findings, expanded indications for the MIitraClip, and an ACC preview are covered in this week's podcast.

N of 1 hypertension trials, heart failure readmissions and HRRP, insulin, CTA vs functional stress testing, and the ongoing paclitaxel PAD controversy are discussed in this week's podcast.

Lead extraction, AF triggers, cognitive decline and CV risk factors, low-value care, and secondary prevention in the real world are discussed in this week's podcast.

Factor Xa reversal agent Andexa, PTSD, gender transition hormones and CVD, primary care physician shortage, and a commentary from a young interventional cardiologist are discussed this week.

The cost of cardiac care, statin adherence and mortality, syncope, ultra-processed food, and heart failure survival are discussed in this week's podcast.

Statins in the elderly, donor hearts and the opioid crisis, Impella, coronary calcium in exercisers, and the plateau in heart disease deaths are discussed in this week's podcast.

New guidelines for atrial fibrillation, PFO closure for stroke prevention, fried chicken, skipping breakfast and e-cigarettes are discussed in this week's podcast.

Aspirin for primary prevention, alcohol and Afib, high-sensitivity troponin, and women in interventional cardiology are discussed in this week's podcast.

Burnout, aspiration thrombectomy, fish intake, insurance coverage, and the gout drug febuxostat are discussed in this week's podcast.

Appropriate use criteria for imaging, HRRP efficacy, medical marijuana, radiation exposure in the cath lab, and hormone therapy are the topics discussed this week's podcast.

The cost of treating high blood pressure, heart-failure readmission policies, abdominal fat, low flow/low gradient aortic stenosis and hypertensive disorders of pregnancy are discussed this week.

Dr John Mandrola discusses upcoding for PCI, hypertension, a pacing lead issue, a PAD trial discovery, and an FDA warning on fluoroquinolones in this week's podcast.

Carotid stents, more stem-cell retractions, AHA statement on statin safety, flu vaccine rules, medication errors, veterans care, and wasteful NIH research on golfing are discussed in this week's podcast.

Measures of hospital quality, statin under- or over-use, Botox for AF, smoking cessation and translating trial evidence to clinical practice are discussed in this week's podcast.