Mini Episode: The Saga of the Cardiac Action Potential
The Poison Lab · Clinical Toxicology LLC
August 26, 202020m 27sbonus
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Show Notes
- Action potential
- Sodium/Potassium ATPase pumps create more positively charged ions outside the cell than inside the cell, this creates a relative negative charge in the cell
- Phase 4- Resting (~ -90 mv)
- Phase 0- Sodium enters the cell (+10 mv)
- Phase 1- Potassium efflux from cell as now there is no negative charge holding it in (0 mv)
- Phase 2- Calcium channels open and allow calcium in, calcium triggers the ryandoine receptor and allows for calcium dependent calcium release from the sarcoplasmic reticulum occurs
- Phase 3- Potassium continues to leave the cell allowing return to -90 mv
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