Mini Episode: Bridging the Gap- Bupropion's not your average wide QRS with Dr. Travis Olives
The Poison Lab · Clinical Toxicology LLC
February 15, 202318m 21sbonus
Audio is streamed directly from the publisher (pdcn.co) as published in their RSS feed. Play Podcasts does not host this file. Rights-holders can request removal through the copyright & takedown page.
Show Notes
- Rohr 2004- Gap junction blockade can cause a wide QRS
- Vink 2004 Connexin 43 is the most important protein for connexon formation and cardiac signal transmission
- Callier 2012- Bupropion does not block sodium channels, and does exhibit similar effects on the cardiac action potential as known gap junction
- Burnham 2014 Bupropion has an IC50 for connexin 43 >50 uMol, larger than other drugs such as fluoextine and lamotrigine
- Shaikh Quereshi 2014 Bupropion interferes with connexin43 production and localization in chicken cardiac myoctes at concentration >50 uMol
Support the show
Review the show where ever your listening
Get Messages from Toxo (Join the Newsletter!)
- Ad free episodes
- Bonus content and early access
- Discounts and give aways on GOTA PICCEM Mushroom card game
The GOTTA PICCEM Poisonous Mushroom Game!
The Poisonus Fungus Amongus Children's Book!
Tox trinkets (Rep the show at home!)
Reach the show
- Email: [email protected]
More Show Resources