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Fear in Our Bones
Season 1 · Episode 77

Fear in Our Bones

Targeting Osteocalcin as a Potential New Therapy for Stress and Anxiety

The People's Scientist · Dr. Stephanie Caligiuri

October 11, 202018m 55s

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Show Notes

Today in Episode 77, I stay on topic with some October/Halloween themes and talk about some new research on how our fear/stress response originates from our skeleton. For many years we thought our fear/stress response originated from our adrenal glands, noradrenaline, and the locus coeruleus of our brain. In this study for the first time, scientists show that our bones respond to stress by releasing a protein called osteocalcin in order to facilitate the physiological response to stress. Why is this information important? Because now it gives us a brand new target, our skeleton, in order to develop new treatments for anxiety and stress related disorders. Tune in for the details!


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