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The Long Run with Luke Timmerman

The Long Run with Luke Timmerman

200 episodes — Page 1 of 4

Ep202: Becky Pferdehirt on Reimagining Science for the AI Era

Jun 2, 20261h 8m

Ep201: Jeremy Levin on Biotech in the Balance

May 19, 20261h 8m

Ep200: Richard Pops on Orexin Drugs For Sleep Disorders & More

May 5, 20261h 13m

Ep199: Martin Burke on Making Small Molecule Medicines for the AI Era

Apr 21, 20261h 10m

Ep198: Abbas Kazimi on Computation and Culture for Drug Discovery

Abbas Kazimi, CEO of Boston-based Nimbus Therapeutics, on computation and culture for drug discovery.

Apr 7, 20261h 16m

Ep197: Viswa Colluru on Discovering Drugs Inspired by Mother Nature

Viswa Colluru, founder and CEO of Boulder, Colo.-based Enveda, on drug discovery with a chemistry platform inspired by natural products.

Mar 31, 20261h 16m

Ep196: Otello Stampacchia on Europe's Biotech Crisis

Otello Stampacchia, founder and managing director of Omega Funds, on attempting to reform Europe's biotech investment climate.

Mar 17, 20261h 3m

Ep195: Ken Song on T-cell Engagers for Autoimmune Diseases

Ken Song, CEO of San Diego-based Candid Therapeutics, on developing bispecific T-cell engaging antibodies for autoimmune disease.

Mar 3, 20261h 5m

Ep194: Ansu Satpathy on Cancer and Autoimmune Drug Discovery

Ep194: Ansu Satpathy on Cancer and Autoimmune Drug Discovery by Timmerman Report

Feb 17, 20261h 8m

Ep193: Ron Renaud on Helping People Lose Weight With GLP-1 Medicines

Ron Renaud, CEO of Waltham, Mass.-based Kailera Therapeutics, on developing GLP-1 based medicines to help people lose weight and live healthier lives.

Jan 22, 20261h 5m

Ep192: Kate Haviland on Following the Science to Precision Immunology

Kate Haviland, former CEO of Blueprint Medicines, on how the company transitioned to a precision immunology company and was acquired by Sanofi for $9.5 billion.

Jan 8, 20261h 26m

Ep191: Emily Conley on Small Molecules to Correct a Rare Kidney Disease

Emily Conley, CEO of Berkeley, CA-based Renasant Bio, on developing small molecule correctors and potentiators for autosomal dominant polycystic kidney disease (ADPKD).

Dec 15, 20251h 7m

Ep190: Neil Kumar on Building a Rare Disease Drug Company

Neil Kumar is founder and CEO of Palo Alto, Calif.-based BridgeBio Pharma, a rare disease drug developer.

Nov 20, 20251h 13m

Ep189: Marc Tessier-Lavigne on Reinventing Drug Discovery with AI

Marc Tessier-Lavigne, CEO of South San Francisco-based Xaira Therapeutics, on reinventing drug discovery with AI.

Nov 12, 20251h 12m

Ep188: Art Krieg on Innate Immune System Activators for Cancer

Art Krieg, founder and CEO of Zola Therapeutics, on developing innate immune system activators for cancer.

Oct 28, 20251h 9m

Ep187: Eric Fischer on Creating a New Class of Medicines

Eric Fischer, a professor at Dana-Farber Cancer Institute, on creating a new class medicines -- targeted protein degraders.

Oct 14, 20251h 5m

Ep186: Bruce Levine & Mags McCarthy on a Song About Science and Hope

Bruce Levine, a CAR-T cell therapy researcher at the University of Pennsylvania, and Mags McCarthy, a country music star, discuss their new song about science and hope for cancer patients.

Sep 29, 20251h 2m

Ep185: Dr. Lachelle Weeks on Predicting Leukemia Risk At Scale

Dr. Lachelle Weeks is a physician-scientist at Dana-Farber Cancer Institute working on a project to predict leukemia risk based on widely available blood samples.

Sep 17, 20251h 5m

Ep184: Jen Adair on Affordable, Accessible Gene & Cell Therapies

Jen Adair, professor and associate director of the Horae Gene Therapy Center at the University of Massachusetts Chan Medical School, on creating more affordable and accessible cell and gene therapies.

Aug 28, 20251h 50m

Ep183: Sabah Oney on CAR-T Cells Against Solid Tumors

Sabah Oney, CEO of Philadelphia and San Francisco-based Dispatch Biotherapeutics, on engineering CAR-T cells that can kill solid tumors.

Aug 6, 202556 min

Ep182: Andy Rachleff & Yung Lie on Creative Ways to Back Science

Andy Rachleff and Yung Lie, board chair and CEO of Damon Runyon Cancer Research Foundation, on creative ways to support science amid budget cuts.

Jul 23, 20251h 1m

Ep181: Claire Mazumdar on a Two-Pronged Attack Against Cancer

Claire Mazumdar, CEO of Boston-based Bicara Therapeutics, on developing a bifunctional antibody for head and neck cancer.

Jul 1, 202557 min

Ep180: John Rinn on Discovering Drugs Based on Long Non-Coding RNA

John Rinn, professor at the University of Colorado and co-founder of Lincswitch Therapeutics, on exploring long non-coding RNA.

Jun 11, 20251h 10m

Ep179: Ethan Weiss & Josh Lehrer on a New Idea for Cardiovascular Disease & Diabetes

Marea Therapeutics CEO Josh Lehrer and CSO Ethan Weiss on a new angle of attack against cardiovascular disease and diabetes.

May 28, 20251h 3m

Ep178: Peyton Greenside on ML-Guided Biologics Discovery

Peyton Greenside, co-founder and CEO of BigHat Biosciences, on machine-learning guided biologic drug discovery.

May 13, 20251h 2m

Ep177: Kevin Parker on Finding Cancer Drug Targets

Kevin Parker, CEO of Cartography Biosciences, on finding new cancer drug targets.

Apr 14, 202558 min

Ep176: David Roblin on Building a TechBio Company

David Roblin, CEO of London-based Relation Therapeutics, on building a techbio discovery company.

Mar 31, 20251h 19m

Ep175: Andy Scharenberg on in vivo CAR-T cell therapies

Andy Scharenberg, CEO of Seattle-based Umoja Biopharma, on developing in vivo CAR-T cell therapies.

Mar 16, 20251h 10m

Ep174: Najat Khan on the TechBio Movement

Najat Khan, chief R&D and chief commercial officer of Recursion, on using technology to improve drug discovery.

Mar 3, 20251h 7m

Ep173: Robert Blum on Building a Fully Integrated Biopharma For Muscle Disorders

Robert Blum, CEO of South San Francisco-based Cytokinetics, on building a fully integrated biopharma to treat muscle disorders.

Feb 11, 202557 min

Ep172: Mostafa Ronaghi on Studying Live Cells at Scale

Mostafa Ronaghi, co-founder and executive board member of Cellanome, on developing technology to look at live cells and cellular interactions at scale.

Jan 27, 20251h 20m

Ep171: Ram Aiyar on RNA Editing Medicines

Ram Aiyar, CEO of Cambridge, Mass.-based Korro Bio, on RNA editing medicines.

Jan 13, 20251h 1m

Ep170: David Schenkein on Investing in the Future of Biotech

David Schenkein, general partner at GV, on investing in the future of biotech.

Jan 2, 202559 min

Ep169: Kevin Fitzgerald on the Past & Future of RNAi Medicines

Alnylam Pharmaceuticals chief scientific officer Kevin Fitzgerald on the past, present & future of RNA interference medicines.

Dec 11, 20241h 2m

Ep168: Jonathan Bricker on How to Quit Smoking & Prevent Cancer

Jonathan Bricker, professor in the cancer prevention program at Fred Hutchinson Cancer Center, on how to quit smoking with help from tech and biotech tools.

Nov 25, 20241h 0m

Ep167: Leslie Williams on transfer RNA therapies

Leslie Williams, CEO of Boston-based hC Bioscience, on developing transfer RNA therapies.

Nov 6, 20241h 11m

Ep166: Chris Garcia on Engineering Protein Drugs for Cancer, Autoimmunity

Chris Garcia, professor at Stanford University and co-founder of several biotech startups, on using protein engineering to advance new treatments for cancer and autoimmune diseases.

Oct 15, 20241h 3m

Ep165: Zach Hornby on Tackling Cancer Drug Resistance

Zach Hornby, CEO of San Diego-based Boundless Bio, on tackling cancer drug resistance.

Sep 26, 20241h 2m

Ep164: Ted Love and Alan Anderson on Raising the Bar for Sickle Cell Disease Patients

Ted Love, chairman of BIO, and Dr. Alan Anderson, executive director of Sickle Forward, on how to improve quality of life for sickle cell disease patients around the world.

Sep 5, 202456 min

Ep163: Sarah Boyce on RNA Medicines for Muscle Diseases

Sarah Boyce, CEO of San Diego-based Avidity Biosciences, on RNA medicines for rare muscle diseases.

Aug 14, 20241h 8m

Ep162: Sean McClain on AI for Biologic Drug Discovery

Sean McClain, CEO of Absci, on using AI to speed up biologic drug discovery.

Jul 16, 20241h 5m

Ep161: Jeff Stein on a Long-Lasting Flu Drug

Jeff Stein, CEO of San Diego-based Cidara Therapeutics, on a long-lasting drug against flu.

Jul 1, 20241h 8m

Ep160: Abe Ceesay on Precision Neuroscience

Abe Ceesay, CEO of Boston-based Rapport Therapeutics, on a precision medicine approach to neuroscience drug discovery.

Jun 17, 20241h 8m

Ep159: Jimi Olaghere on Being Functionally Cured of Sickle Cell Disease

Jimi Olaghere is one of the first patients to have been functionally cured of sickle cell disease with a CRISPR gene-edited cell therapy.

Jun 3, 20241h 7m

Ep158: David Younger and Randolph Lopez on SynBio & AI for Discovery

David Younger and Randolph Lopez, co-founders of A-Alpha Bio, on using synthetic biology and AI to discover new biologic drugs.

May 20, 20241h 0m

Ep157: Vineeta Agarwala of A16Z on Investing in AI for Drug Discovery

Vineeta Agarwala, general partner at A16Z's Bio & Health fund, on investing in AI for drug discovery.

May 1, 202456 min

Ep156: David Liu on New Tools and Techniques for Biology

David Liu, professor of chemistry at Harvard University and co-founder of multiple biotech companies, including Beam Therapeutics and Prime Medicine.

Apr 16, 20241h 52m

Ep155: Valerie Daggett on Early Detection, and Treatment, of Alzheimer's

Valerie Daggett, founder and CEO of Seattle-based AltPep, on early detection and treatment of Alzheimer's.

Mar 6, 20241h 2m

Ep154: Robert Ang on CRISPR to Protect Bone Marrow & Attack Cancer

Robert Ang, CEO of Cambridge, Mass.-based Vor Bio, on using CRISPR gene editing to alter bone marrow transplants and improve treatment of acute myeloid leukemia.

Feb 9, 20241h 3m

Ep153: Rick Young on Studying Gene Expression for Drug Discovery

Rick Young, professor at MIT and co-founder of Syros Pharmaceuticals, CAMP4 Therapeutics, Omega Therapeutics, and Dewpoint Therapeutics, on studying gene expression for drug discovery.

Jan 22, 20241h 1m