Guest:
Dr. Jeffrey Rathmell is the Cornelius Vanderbilt Professor of Immunobiology at the Vanderbilt Center for Immunobiology. His research focuses on T cell metabolism in cancer. He talks about what T cells use for fuel and his work on fatty acid synthesis. He also discusses the ‘obesity paradox’ in cancer immunotherapy and his favorite parts of being a scientist and professor.
Featured Products and Resources:
- The Immunology Podcast has been nominated for a People’s Choice Podcast Award!
- Differentiate human monocytes into macrophages with STEMCELL’s ImmunoCult-XF Macrophage Medium.
The Immunology Round Up
A Humanized Mouse Model – A new humanized mouse mounts specific and mature antibody and autoantibody responses.
IL-11 Signaling in Aging – Inhibiting IL-11 extends the healthspan and lifespan of mice.
Sphinganine Synthesis in Macrophages – Sphinganine biosynthesis is a checkpoint for macrophage pattern recognition in mouse models of sepsis and melanoma.
Brain-Muscle Signaling – Researchers identified a brain-to-muscle signaling axis in Drosophila that regulates muscle performance.
Image courtesy of Dr. Jeffrey Rathmell