Guest:
Dr. Frances Lund is the Charles H. McCauley Professor and Chair of the Department of Microbiology at the University of Alabama at Birmingham. Her lab showed that B cells not only make antibodies, but also produce cytokines that modulate the microenvironment. She currently studies the many roles of B cells, how to target B cells gone bad, and nasal vaccines for respiratory illnesses.
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The Immunology Science Round Up
A COVID-19 Vaccine Targeting CD40 – Researchers fused a CD40 monoclonal antibody to a SARS-CoV-2 protein, which stimulated dendritic cells and boosted the immune response of monkeys already exposed to the virus.
A T Cell Cancer Vaccine – Scientists generated a therapeutic cancer vaccine by genetically modifying T cells to deliver antigens and adjuvant signals to lymphoid tissues.
Dendritic Cells in Intestinal Immunity – Intestinal dendritic cells have local specializations that depend on the microenvironment.
Stress and the Immune System – Psychological stress primes monocytes to an inflammatory state.
Image courtesy of Dr. Frances Lund