Peptides, Hormones & Strength: What Actually Works in Midlife with Dr. Chris Asandra and Maria Chase
The Iconic Midlife with Roxy Manning · Roxy Manning
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Show Notes
What happens when the workouts that used to work… stop working?
So many women hit their 40s and feel like the rules suddenly changed.
Energy shifts. Sleep becomes unpredictable. Muscle feels harder to maintain. And despite doing all the “right” things, the results don’t always follow.
In this episode of The Iconic Midlife, we’re breaking down what’s actually happening in the body during midlife — and how women can rethink fitness, metabolism, and recovery in a way that actually works.
I’m joined by Dr. Chris Asandra, a physician specializing in regenerative and longevity medicine, and Maria Chase, founder of BURN LA, a fitness studio with a front-row seat to how women’s bodies and needs evolve over time.
Together, we explore the intersection of hormones, strength training, and metabolic health — and unpack one of the most talked-about (and misunderstood) topics in wellness right now: peptides.
This is a conversation about cutting through the noise — and understanding what truly matters if you want to feel strong, energized, and confident in midlife.
In This Episode, We Cover:
- What’s actually happening in the body during perimenopause and midlife
- Why workouts that once worked may stop delivering the same results
- The critical role of muscle in metabolism, energy, and long-term health
- How women should be thinking about strength training in their 40s and beyond
- The balance between pushing your body and prioritizing recovery
- Wellness trends vs. real science — what’s worth your time and what’s not
- Peptides explained: what they are, how they work, and whether they live up to the hype
- The biggest misconceptions women have about aging, fitness, and hormones
- Simple, actionable shifts to feel better in your body over the next six months
About the Guests:
Dr. Chris Asandra is a physician specializing in regenerative medicine, hormone optimization, and longevity-focused care. His work focuses on helping patients optimize performance, recovery, and long-term health through advanced medical and wellness strategies.
Maria Chase is the founder of BURN LA, a Los Angeles-based fitness studio known for its high-energy, results-driven approach to strength and conditioning across all stages of life.
If This Episode Resonated:
Share it with a friend who’s navigating midlife and trying to make sense of the changes happening in her body.
And if you’re enjoying the show, make sure you’re following The Iconic Midlife on your favorite podcast platform — it helps more women discover these conversations.
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Listen on:
Apple Podcasts: https://podcasts.apple.com/us/podcast/the-iconic-midlife-with-roxy-manning/id1817484587
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Let’s Connect
Social media: @theiconicmidlife (show) | @redcarpetroxy (host)
• YouTube: https://youtube.com/@theiconicmidlife
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