In this episode we discuss:
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Why hypothyroidism is not the root cause of your issues
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Why TSH on its own is not a good marker of thyroid status
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The importance of thyroid hormones for sex hormone production, gut health, and immune function
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T3’s effects on autophagy, mitochondrial biogenesis, and uncoupling
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Whether low thyroid activity is beneficial for longevity and aging and when a high TSH may be a good sign
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Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-95-hypothyroidism-in-context-thyroid-hormone-basics-hypothyroidism-part-1/
Timestamps:
0:00 – intro
1:19 – an introduction to hypothyroidism and common symptoms of hypothyroidism
9:02 – the broader biological context of hypothyroidism and hypothyroidism as a low metabolic state
12:45 – why hypothyroidism is not the root cause
16:23 – the basics of the different thyroid hormones and their regulation
19:54 – the hypothalamic-pituitary-thyroid axis and the nuances within the negative feedback loops
24:45 – the basics of thyroid hormone production
29:37 – the basics of thyroid hormone conversion
35:17 – the larger context of thyroid hormone production and conversion
38:58 – the basics of thyroid hormone transport
41:44 – the basics of thyroid hormone uptake
46:23 – the nutrients involved in thyroid hormone production and conversion
50:26 – the cellular effects of T3 (metabolic stimulation, uncoupling, autophagy, mitochondrial biogenesis, steroidogenesis from cholesterol)
57:29 – the effects of T3 on gut health, immune function, and aging
1:03:08 – whether low thyroid activity is beneficial for longevity and aging and when a high TSH may be a good sign
1:08:41 – the relationship between vitamin A and thyroid hormones
