EB. 68: Oxidative Stress, Choline Deficiency, and Exporting Liver Fat (NAFLD Part 6)

In this episode we discuss:

• How excess oxidative stress causes fat to accumulate in the liver

• How a choline or methionine deficiency can contribute to fatty liver

• Another mechanism by which PUFA cause fatty liver disease

• How folate and vitamin B12 deficiencies can contribute to fatty liver

• How PUFA decrease LDL and why this is NOT beneficial for general metabolic health or liver health

 

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Click here to check out the show notes: https://jayfeldmanwellness.com/ep-68-oxidative-stress-choline-deficiency-and-exporting-liver-fat-nafld-part-6/

 

Timestamps:

3:48 – how fat gets exported from our livers and why it matters in NAFLD

8:40 – how a choline, methionine, folate, or B12 deficiency can inhibit the liver’s ability to export fat

19:05 – how oxidative stress caused by PUFA and other factors inhibits the liver’s ability to export fat

27:50 – research showing that PUFA causes oxidative stress that inhibits the liver’s ability to export fat

42:11 – why lowering LDL by eating PUFA is NOT beneficial, both for general metabolic health and liver health

59:57 – other factors that drive oxidative stress and inhibit the liver’s ability to export fat