EB. 137: What REALLY Causes Glycation (Is Sugar Really the Problem?)
Audio is streamed directly from the publisher (mcdn.podbean.com) as published in their RSS feed. Play Podcasts does not host this file. Rights-holders can request removal through the copyright & takedown page.
Show Notes
-
Why glucose and fructose are not the primary drivers of AGE formation
-
Whether blood sugar spikes cause glycation
-
How fats and ketones can cause glycation
-
What’s really responsible for glycation in type 2 diabetes
-
Whether fructose causes more glycation than glucose
Check out the Energy Balance Mini-Course here: https://www.jayfeldmanwellness.com/energy/
Check out the Energy Balance Food guide here: https://www.jayfeldmanwellness.com/guide/
Check out the Energy Balance Solution Program here:
https://www.jayfeldmanwellness.com/energy-balance-solution/
Click here to check out the show notes:
https://www.jayfeldmanwellness.com/eb-137-what-really-causes-glycation-is-sugar-really-the-problem/
0:00 – intro
0:46 – common beliefs about carbohydrates and glycation
2:35 – what are glycation and advanced glycation end products?
6:57 – the process of glycation from glucose
9:30 – is sugar the only source of AGEs?
15:00 – primary drivers of glycation: dicarbonyls
19:30 – how fatty acids, amino acids, and ketones cause AGE formation
21:23 – how increased gluconeogenesis on low-carb diets increases AGE formation
22:53 – glucose metabolism produces very few glycation products in the context of a healthy metabolism
25:33 – omega-6s form AGEs more than 10x faster than glucose
28:24 – the role of ALEs (advanced lipoxidation end products) in glycation and chronic disease
30:36 – whether blood sugar spikes cause glycation
38:52 – whether fructose causes more glycation (or fructation) than glucose
47:05 – can glycation from fructose (fructation) be measured, and does this matter?
52:06 – problems with research looking at fructose’s AGE formation in animal models