
🧬 The Mayan Negotiation Secret That Built A Biotech Company | Jake Glanville Re-Release (1/4)
"You don't always know at the time how something will be useful in the future, but if you keep following what fascinates you, those threads can re-synthesize into something powerful down the line." We’re revisiting some of our previous episodes over the holidays this year. Our next re-release is this episode of The Biotech Startups Podcast, where computational immuno-engineer and serial entrepreneur Jake Glanville shares how growing up in a Mayan Tzʼutujil village in Guatemala during a civil war shaped his path into biotech. He reflects on living amid limited access to medicine, navigating personal health challenges like asthma, and witnessing how simple interventions such as deworming transformed entire communities, inspiring his commitment to developing therapeutics and vaccines. Jake discusses the profound influence of his grandfather, a Rocketdyne engineer who worked on the engines that sent humans to the moon, and how that legacy lowered his sense of what is "impossible" in science. Watching his parents run a hotel and restaurant gave him an education in operations, resilience, and people management—skills that translated directly into building biotech companies. He also unpacks the negotiation lessons he absorbed from Mayan market culture, where the goal is sustainable, mutual value rather than one-time wins. The episode follows Jake's transition to the United States after his father's autoimmune disease diagnosis, his strategic decision to attend UC Berkeley, and how his self-taught programming background fused with population genetics to create a passion for computational immunology.
The Biotech Startups Podcast · Excedr
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Show Notes
- Growing Up in Guatemala: How limited healthcare and infectious disease exposure motivated Jake's focus on medicine and immunology
- Family Influences: The impact of a rocket engineer grandfather, entrepreneurial parents, and an artist mother on his scientific ambition
- Entrepreneurial Mindset: Lessons in operations, problem-solving, and people management from running a restaurant in volatile conditions
- Mayan Negotiation Principles: Market-born lessons in fair, relationship-focused deal-making and being "pushy smooth"
- Berkeley and Computational Immunology: Combining molecular biology, population genetics, and programming to analyze immune diversity
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